Rattus norvegicus

107 known processes

Calr

calreticulin

Calr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein transport GO:0015031 132 0.247
Human
intracellular transport GO:0046907 185 0.207
Human
programmed cell death GO:0012501 392 0.201
regulation of apoptotic process GO:0042981 335 0.176
cellular macromolecule catabolic process GO:0044265 29 0.175
establishment of protein localization GO:0045184 141 0.175
Human
cellular component assembly GO:0022607 360 0.141
Mouse
catabolic process GO:0009056 351 0.126
regulation of programmed cell death GO:0043067 341 0.117
cellular macromolecule localization GO:0070727 122 0.109
Human Mouse
response to hypoxia GO:0001666 231 0.108
cellular protein localization GO:0034613 122 0.107
Human Mouse
macromolecule localization GO:0033036 252 0.101
Human Mouse
cellular response to topologically incorrect protein GO:0035967 3 0.078
macromolecule catabolic process GO:0009057 58 0.073
er associated ubiquitin dependent protein catabolic process GO:0030433 1 0.072
cellular catabolic process GO:0044248 295 0.071
macromolecular complex subunit organization GO:0043933 339 0.071
Mouse
regulation of anatomical structure morphogenesis GO:0022603 141 0.070
Human
anatomical structure morphogenesis GO:0009653 298 0.061
Human Fly
organic substance catabolic process GO:1901575 316 0.059
proteasomal protein catabolic process GO:0010498 8 0.058
regulation of anatomical structure size GO:0090066 135 0.058
cell cell signaling GO:0007267 335 0.058
single organism intracellular transport GO:1902582 166 0.056
Human
negative regulation of apoptotic process GO:0043066 181 0.055
cellular response to stress GO:0033554 269 0.055
Human Mouse
single organism organelle organization GO:1902589 180 0.055
Mouse
proteolysis GO:0006508 175 0.051
single organism membrane organization GO:0044802 74 0.050
localization of cell GO:0051674 202 0.050
Human
modification dependent macromolecule catabolic process GO:0043632 14 0.049
cellular protein catabolic process GO:0044257 19 0.049
response to cytokine GO:0034097 215 0.048
membrane organization GO:0061024 94 0.046
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.046
regulation of cellular protein metabolic process GO:0032268 267 0.045
negative regulation of programmed cell death GO:0043069 183 0.043
apoptotic process GO:0006915 381 0.042
macromolecular complex assembly GO:0065003 273 0.042
Mouse
protein localization GO:0008104 191 0.039
Human Mouse
synaptic transmission GO:0007268 235 0.038
neural crest cell development GO:0014032 2 0.038
dna metabolic process GO:0006259 96 0.038
Human
cellular metal ion homeostasis GO:0006875 172 0.038
response to purine containing compound GO:0014074 126 0.037
chemical homeostasis GO:0048878 292 0.037
regulation of behavior GO:0050795 61 0.036
Human
positive regulation of cellular component organization GO:0051130 200 0.036
Human Mouse
negative regulation of cell death GO:0060548 229 0.034
modification dependent protein catabolic process GO:0019941 14 0.033
cellular response to endogenous stimulus GO:0071495 377 0.031
cellular component biogenesis GO:0044085 368 0.031
Mouse
negative regulation of cell communication GO:0010648 158 0.030
Human
cellular component morphogenesis GO:0032989 155 0.030
Human
carbohydrate derivative metabolic process GO:1901135 346 0.030
heterocycle catabolic process GO:0046700 167 0.030
cellular response to unfolded protein GO:0034620 2 0.030
golgi vesicle transport GO:0048193 22 0.029
positive regulation of developmental process GO:0051094 283 0.029
Human
purine nucleoside catabolic process GO:0006152 124 0.029
regulation of cell morphogenesis GO:0022604 77 0.028
Human
cellular ion homeostasis GO:0006873 184 0.028
signal release GO:0023061 145 0.028
endoplasmic reticulum unfolded protein response GO:0030968 2 0.028
positive regulation of immunoglobulin production GO:0002639 4 0.028
regulation of secretion GO:0051046 224 0.027
response to decreased oxygen levels GO:0036293 237 0.026
protein targeting GO:0006605 61 0.026
cellular response to organonitrogen compound GO:0071417 197 0.026
response to other organism GO:0051707 220 0.026
secretion by cell GO:0032940 248 0.025
positive regulation of response to stimulus GO:0048584 285 0.025
Human
negative regulation of gene expression GO:0010629 199 0.025
organelle organization GO:0006996 266 0.025
Mouse
positive regulation of multicellular organismal process GO:0051240 387 0.025
response to endoplasmic reticulum stress GO:0034976 10 0.025
regulation of cell migration GO:0030334 128 0.024
Human
regulation of signal transduction GO:0009966 318 0.024
Human
regulation of actin nucleation GO:0051125 2 0.024
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.024
regulation of metal ion transport GO:0010959 118 0.024
protein catabolic process GO:0030163 30 0.024
regulation of cell development GO:0060284 263 0.024
Human
head development GO:0060322 247 0.023
Fly
nucleotide metabolic process GO:0009117 279 0.023
regulation of synaptic transmission GO:0050804 141 0.023
cellular amine metabolic process GO:0044106 38 0.023
central nervous system development GO:0007417 311 0.023
Fly
regulation of cell differentiation GO:0045595 320 0.023
Human
ras protein signal transduction GO:0007265 29 0.022
protein complex subunit organization GO:0071822 302 0.022
Mouse
neural crest cell migration GO:0001755 1 0.022
positive regulation of protein metabolic process GO:0051247 178 0.022
regulation of arp2 3 complex mediated actin nucleation GO:0034315 2 0.021
multicellular organism reproduction GO:0032504 233 0.021
protein localization to membrane GO:0072657 36 0.021
dephosphorylation GO:0016311 98 0.021
cytoskeleton dependent cytokinesis GO:0061640 2 0.021
multicellular organismal reproductive process GO:0048609 233 0.021
response to biotic stimulus GO:0009607 226 0.021
neurological system process GO:0050877 219 0.021
Fly
neural crest cell differentiation GO:0014033 2 0.020
regulation of cell motility GO:2000145 131 0.020
Human
regulation of locomotion GO:0040012 148 0.020
Human
regulation of cellular component organization GO:0051128 368 0.020
Human Mouse
ribose phosphate metabolic process GO:0019693 235 0.020
divalent inorganic cation transport GO:0072511 134 0.019
cation transport GO:0006812 382 0.019
calcium ion homeostasis GO:0055074 162 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.019
Human
lipid storage GO:0019915 1 0.019
carbohydrate derivative catabolic process GO:1901136 147 0.018
blood circulation GO:0008015 183 0.018
aging GO:0007568 241 0.018
Human Mouse
response to nutrient levels GO:0031667 370 0.018
protein oligomerization GO:0051259 191 0.018
protein complex assembly GO:0006461 263 0.018
Mouse
cellular cation homeostasis GO:0030003 180 0.018
cytosolic calcium ion homeostasis GO:0051480 140 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.017
posttranscriptional regulation of gene expression GO:0010608 37 0.017
protein localization to organelle GO:0033365 57 0.017
Human Mouse
regulation of canonical wnt signaling pathway GO:0060828 4 0.017
regulation of hydrolase activity GO:0051336 143 0.017
ubiquitin dependent protein catabolic process GO:0006511 14 0.017
positive regulation of cellular biosynthetic process GO:0031328 295 0.016
Human
transmembrane transport GO:0055085 412 0.016
dendritic spine organization GO:0097061 12 0.016
heart morphogenesis GO:0003007 3 0.016
synaptic growth at neuromuscular junction GO:0051124 1 0.016
cell cycle GO:0007049 101 0.016
Human Mouse
nucleoside triphosphate catabolic process GO:0009143 123 0.015
cellular response to nitrogen compound GO:1901699 210 0.015
single organism catabolic process GO:0044712 283 0.015
regulation of systemic arterial blood pressure GO:0003073 30 0.015
nucleoside phosphate metabolic process GO:0006753 283 0.015
cellular divalent inorganic cation homeostasis GO:0072503 162 0.015
cytoplasmic transport GO:0016482 115 0.015
Human
regulation of tube size GO:0035150 89 0.015
positive regulation of cell communication GO:0010647 271 0.015
response to growth factor GO:0070848 189 0.015
male gamete generation GO:0048232 99 0.015
chromosome condensation GO:0030261 3 0.015
negative regulation of signaling GO:0023057 157 0.015
Human
response to extracellular stimulus GO:0009991 380 0.015
positive regulation of cell death GO:0010942 184 0.015
regulation of nervous system development GO:0051960 264 0.014
Human
cellular chemical homeostasis GO:0055082 247 0.014
aromatic compound catabolic process GO:0019439 168 0.014
arp2 3 complex mediated actin nucleation GO:0034314 2 0.014
response to oxygen levels GO:0070482 265 0.014
muscle contraction GO:0006936 88 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.014
tube development GO:0035295 89 0.014
gastrulation GO:0007369 2 0.014
multicellular organismal signaling GO:0035637 44 0.014
neural tube formation GO:0001841 1 0.014
regulation of hormone levels GO:0010817 187 0.014
intracellular signal transduction GO:0035556 314 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
locomotion GO:0040011 237 0.013
Human Fly
regulation of cellular component size GO:0032535 51 0.013
response to wounding GO:0009611 254 0.013
muscle system process GO:0003012 115 0.013
nucleotide catabolic process GO:0009166 139 0.013
muscle structure development GO:0061061 87 0.013
angiogenesis GO:0001525 53 0.013
purine ribonucleoside metabolic process GO:0046128 168 0.013
ear development GO:0043583 21 0.013
cytokinetic process GO:0032506 1 0.013
regulation of cellular localization GO:0060341 263 0.013
endocytosis GO:0006897 84 0.013
Mouse
innate immune response GO:0045087 35 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
cell projection organization GO:0030030 302 0.013
organophosphate catabolic process GO:0046434 148 0.013
cell motility GO:0048870 202 0.013
Human
homeostatic process GO:0042592 331 0.013
tube formation GO:0035148 3 0.013
purine containing compound metabolic process GO:0072521 253 0.013
regulation of phosphate metabolic process GO:0019220 349 0.012
cellular modified amino acid metabolic process GO:0006575 61 0.012
intracellular protein transport GO:0006886 79 0.012
Human
positive regulation of molecular function GO:0044093 230 0.012
regulation of synaptic plasticity GO:0048167 70 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
Human
dendritic spine development GO:0060996 20 0.012
sexual reproduction GO:0019953 148 0.012
secretion GO:0046903 307 0.012
response to inorganic substance GO:0010035 377 0.012
positive regulation of organelle organization GO:0010638 48 0.012
regulation of cellular component biogenesis GO:0044087 86 0.012
protein complex biogenesis GO:0070271 263 0.012
Mouse
gamete generation GO:0007276 124 0.012
immune response GO:0006955 104 0.012
defense response to gram negative bacterium GO:0050829 3 0.012
spermatogenesis GO:0007283 99 0.012
regulation of protein metabolic process GO:0051246 289 0.012
hindbrain morphogenesis GO:0021575 2 0.012
multicellular organism growth GO:0035264 1 0.012
metal ion homeostasis GO:0055065 186 0.012
regulation of immunoglobulin production GO:0002637 4 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
peptide hormone secretion GO:0030072 84 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
neuronal action potential GO:0019228 35 0.012
cell projection morphogenesis GO:0048858 123 0.011
organelle inheritance GO:0048308 2 0.011
regulation of intracellular signal transduction GO:1902531 218 0.011
regulation of cell projection organization GO:0031344 175 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
reproductive process GO:0022414 372 0.011
hormone secretion GO:0046879 115 0.011
regulation of viral transcription GO:0046782 2 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
morphogenesis of embryonic epithelium GO:0016331 3 0.011
transcription dna templated GO:0006351 377 0.011
Human
chromosome segregation GO:0007059 2 0.011
actin nucleation GO:0045010 2 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.011
exocytosis GO:0006887 60 0.011
protein homooligomerization GO:0051260 91 0.011
neuron projection development GO:0031175 273 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
negative regulation of metabolic process GO:0009892 331 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.011
Human
small gtpase mediated signal transduction GO:0007264 36 0.010
negative regulation of synaptic transmission GO:0050805 29 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.010
chaperone mediated protein folding GO:0061077 6 0.010
regulation of organelle organization GO:0033043 80 0.010
Mouse
actin filament organization GO:0007015 42 0.010
positive regulation of signaling GO:0023056 270 0.010
nucleobase containing compound catabolic process GO:0034655 152 0.010

Calr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
sensory system disease DOID:0050155 0 0.030
nervous system disease DOID:863 0 0.030
musculoskeletal system disease DOID:17 0 0.027
muscle tissue disease DOID:66 0 0.022
muscular disease DOID:0080000 0 0.022
myopathy DOID:423 0 0.022