Rattus norvegicus

95 known processes

Camk2b

calcium/calmodulin-dependent protein kinase II beta

(Aliases: Ck2b)

Camk2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
macromolecular complex assembly GO:0065003 273 0.322
protein complex biogenesis GO:0070271 263 0.312
protein complex assembly GO:0006461 263 0.305
divalent inorganic cation transport GO:0072511 134 0.215
Mouse
protein complex subunit organization GO:0071822 302 0.165
neuron projection development GO:0031175 273 0.161
protein oligomerization GO:0051259 191 0.150
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.146
Fly
synaptic transmission GO:0007268 235 0.142
single organism behavior GO:0044708 130 0.137
Fly
cellular component assembly GO:0022607 360 0.130
Fly
cellular component biogenesis GO:0044085 368 0.128
Fly
vesicle mediated transport GO:0016192 181 0.128
synaptic growth at neuromuscular junction GO:0051124 1 0.114
Fly
positive regulation of multicellular organismal process GO:0051240 387 0.107
organic substance catabolic process GO:1901575 316 0.103
cation transport GO:0006812 382 0.102
Mouse
regulation of secretion GO:0051046 224 0.101
carbohydrate derivative metabolic process GO:1901135 346 0.099
macromolecular complex subunit organization GO:0043933 339 0.097
purine containing compound metabolic process GO:0072521 253 0.094
regulation of cellular localization GO:0060341 263 0.092
cell cell signaling GO:0007267 335 0.091
anatomical structure morphogenesis GO:0009653 298 0.090
central nervous system development GO:0007417 311 0.086
response to inorganic substance GO:0010035 377 0.081
Mouse
behavior GO:0007610 205 0.080
Fly
neuron development GO:0048666 286 0.078
reproductive process GO:0022414 372 0.078
Mouse Fly
regulation of cell development GO:0060284 263 0.077
glutamate receptor signaling pathway GO:0007215 43 0.071
cognition GO:0050890 92 0.069
Fly
regulation of vesicle mediated transport GO:0060627 81 0.068
transmembrane transport GO:0055085 412 0.064
regulation of phosphorus metabolic process GO:0051174 349 0.064
nucleobase containing small molecule metabolic process GO:0055086 316 0.064
positive regulation of rna biosynthetic process GO:1902680 197 0.063
neuron death GO:0070997 127 0.063
regulation of multicellular organismal development GO:2000026 376 0.063
positive regulation of developmental process GO:0051094 283 0.062
catabolic process GO:0009056 351 0.062
protein transport GO:0015031 132 0.060
neuron differentiation GO:0030182 368 0.059
macromolecule localization GO:0033036 252 0.059
regulation of neuron projection development GO:0010975 161 0.057
regulation of molecular function GO:0065009 398 0.057
neurological system process GO:0050877 219 0.056
Mouse Fly
positive regulation of cell communication GO:0010647 271 0.056
cellular response to stress GO:0033554 269 0.055
ionotropic glutamate receptor signaling pathway GO:0035235 34 0.053
positive regulation of phosphorus metabolic process GO:0010562 262 0.053
divalent metal ion transport GO:0070838 132 0.053
Mouse
cellular macromolecule localization GO:0070727 122 0.051
cell projection organization GO:0030030 302 0.051
regulation of neuron death GO:1901214 115 0.051
positive regulation of neurogenesis GO:0050769 165 0.049
reproduction GO:0000003 245 0.049
Mouse Fly
protein homooligomerization GO:0051260 91 0.049
negative regulation of cellular metabolic process GO:0031324 281 0.049
negative regulation of phosphorus metabolic process GO:0010563 80 0.049
positive regulation of transport GO:0051050 245 0.048
learning or memory GO:0007611 90 0.047
Fly
regulation of synaptic transmission GO:0050804 141 0.047
single organism catabolic process GO:0044712 283 0.046
regulation of neuron apoptotic process GO:0043523 83 0.045
regulation of neurogenesis GO:0050767 247 0.043
ion homeostasis GO:0050801 212 0.043
organelle localization GO:0051640 55 0.041
oxoacid metabolic process GO:0043436 290 0.040
protein heterooligomerization GO:0051291 89 0.040
head development GO:0060322 247 0.040
secretion GO:0046903 307 0.040
single organism cellular localization GO:1902580 102 0.039
establishment of protein localization GO:0045184 141 0.039
synaptic vesicle docking involved in exocytosis GO:0016081 2 0.039
inorganic cation transmembrane transport GO:0098662 202 0.038
programmed cell death GO:0012501 392 0.038
Mouse
secretion by cell GO:0032940 248 0.038
cellular response to oxygen containing compound GO:1901701 386 0.037
regulation of dendrite development GO:0050773 59 0.037
single organism intracellular transport GO:1902582 166 0.036
intracellular transport GO:0046907 185 0.035
regulation of cell differentiation GO:0045595 320 0.035
cellular homeostasis GO:0019725 252 0.035
nucleotide metabolic process GO:0009117 279 0.034
regulation of membrane potential GO:0042391 110 0.034
regulation of growth GO:0040008 105 0.034
Fly
homeostatic process GO:0042592 331 0.034
organic acid metabolic process GO:0006082 292 0.033
cellular catabolic process GO:0044248 295 0.033
positive regulation of molecular function GO:0044093 230 0.032
endocytosis GO:0006897 84 0.032
calcium ion homeostasis GO:0055074 162 0.032
cellular nitrogen compound catabolic process GO:0044270 163 0.031
regulation of cellular protein metabolic process GO:0032268 267 0.031
negative regulation of macromolecule metabolic process GO:0010605 260 0.031
positive regulation of signaling GO:0023056 270 0.031
carboxylic acid metabolic process GO:0019752 289 0.031
glycosyl compound metabolic process GO:1901657 182 0.030
anterior posterior pattern specification GO:0009952 1 0.030
cellular protein localization GO:0034613 122 0.030
regulation of system process GO:0044057 208 0.030
intracellular signal transduction GO:0035556 314 0.029
regulation of synapse maturation GO:0090128 2 0.029
organophosphate metabolic process GO:0019637 370 0.029
positive regulation of dendritic spine morphogenesis GO:0061003 3 0.029
positive regulation of response to stimulus GO:0048584 285 0.029
Mouse
brain development GO:0007420 247 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.028
positive regulation of neuron projection development GO:0010976 99 0.028
regulation of nervous system development GO:0051960 264 0.028
regulation of phosphate metabolic process GO:0019220 349 0.028
regulation of apoptotic process GO:0042981 335 0.028
Mouse
regulation of nucleotide metabolic process GO:0006140 117 0.028
regulation of purine nucleotide metabolic process GO:1900542 115 0.028
protein phosphorylation GO:0006468 345 0.028
Human Mouse Rat Worm Fly
regulation of cell projection organization GO:0031344 175 0.027
cellular divalent inorganic cation homeostasis GO:0072503 162 0.027
regulation of cellular amine metabolic process GO:0033238 8 0.027
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.027
regulation of anatomical structure morphogenesis GO:0022603 141 0.027
positive regulation of catalytic activity GO:0043085 184 0.027
regulation of programmed cell death GO:0043067 341 0.027
Mouse
regulation of ion transmembrane transport GO:0034765 121 0.027
cell cycle GO:0007049 101 0.027
Mouse Worm
cellular metal ion homeostasis GO:0006875 172 0.026
ribose phosphate metabolic process GO:0019693 235 0.026
chemical homeostasis GO:0048878 292 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.026
divalent inorganic cation homeostasis GO:0072507 165 0.026
cellular response to external stimulus GO:0071496 118 0.026
protein localization GO:0008104 191 0.026
negative regulation of signaling GO:0023057 157 0.026
Mouse
tissue development GO:0009888 252 0.026
microvillus assembly GO:0030033 2 0.026
response to axon injury GO:0048678 59 0.026
negative regulation of cell death GO:0060548 229 0.025
regulation of cell morphogenesis GO:0022604 77 0.025
multicellular organismal reproductive process GO:0048609 233 0.025
Fly
rna metabolic process GO:0016070 406 0.025
response to growth factor GO:0070848 189 0.025
metal ion homeostasis GO:0055065 186 0.024
nucleoside phosphate metabolic process GO:0006753 283 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.024
cellular amino acid metabolic process GO:0006520 107 0.024
apoptotic process GO:0006915 381 0.024
Mouse
calcium ion transport GO:0006816 131 0.024
Mouse
neuron apoptotic process GO:0051402 88 0.024
purine ribonucleotide catabolic process GO:0009154 136 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.023
amine metabolic process GO:0009308 38 0.023
purine containing compound catabolic process GO:0072523 138 0.023
response to hexose GO:0009746 144 0.023
ribonucleoside catabolic process GO:0042454 126 0.023
response to wounding GO:0009611 254 0.023
regulation of protein metabolic process GO:0051246 289 0.023
purine nucleoside catabolic process GO:0006152 124 0.022
organonitrogen compound catabolic process GO:1901565 179 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.022
dendritic spine morphogenesis GO:0060997 9 0.022
heterocycle catabolic process GO:0046700 167 0.022
calcium ion transmembrane transport GO:0070588 70 0.022
purine nucleoside monophosphate metabolic process GO:0009126 84 0.022
regulation of transcription dna templated GO:0006355 374 0.022
cellular response to peptide GO:1901653 133 0.022
signal release GO:0023061 145 0.022
nucleoside triphosphate metabolic process GO:0009141 144 0.022
g protein coupled receptor signaling pathway GO:0007186 242 0.022
aging GO:0007568 241 0.022
response to hydrogen peroxide GO:0042542 89 0.022
axis specification GO:0009798 4 0.022
metal ion transport GO:0030001 289 0.022
Mouse
locomotion GO:0040011 237 0.021
Worm
negative regulation of cell communication GO:0010648 158 0.021
Mouse
regulation of ion transport GO:0043269 245 0.021
developmental process involved in reproduction GO:0003006 159 0.021
purine nucleotide metabolic process GO:0006163 229 0.021
carbohydrate derivative catabolic process GO:1901136 147 0.021
response to oxygen levels GO:0070482 265 0.021
Rat
cellular ion homeostasis GO:0006873 184 0.021
regulation of signal transduction GO:0009966 318 0.021
Mouse
regulation of intracellular signal transduction GO:1902531 218 0.020
cellular response to hormone stimulus GO:0032870 247 0.020
rna biosynthetic process GO:0032774 380 0.020
positive regulation of nucleic acid templated transcription GO:1903508 197 0.020
glycosyl compound catabolic process GO:1901658 126 0.020
monovalent inorganic cation transport GO:0015672 172 0.020
memory GO:0007613 54 0.020
Fly
negative regulation of metabolic process GO:0009892 331 0.020
regulation of cellular component organization GO:0051128 368 0.020
regulation of synapse assembly GO:0051963 15 0.020
Fly
ribose phosphate biosynthetic process GO:0046390 87 0.019
multicellular organism growth GO:0035264 1 0.019
positive regulation of rna metabolic process GO:0051254 203 0.019
ribonucleotide metabolic process GO:0009259 231 0.019
enzyme linked receptor protein signaling pathway GO:0007167 116 0.019
positive regulation of signal transduction GO:0009967 175 0.019
Mouse
regulation of developmental growth GO:0048638 45 0.019
Fly
positive regulation of biosynthetic process GO:0009891 319 0.019
nucleoside phosphate catabolic process GO:1901292 140 0.019
regulation of transmembrane transport GO:0034762 122 0.019
nucleoside metabolic process GO:0009116 179 0.019
cellular calcium ion homeostasis GO:0006874 160 0.018
response to reactive oxygen species GO:0000302 120 0.018
nucleobase containing compound catabolic process GO:0034655 152 0.018
synaptic vesicle endocytosis GO:0048488 4 0.018
response to cytokine GO:0034097 215 0.018
cellular amine metabolic process GO:0044106 38 0.018
cell type specific apoptotic process GO:0097285 134 0.018
regulation of synaptic plasticity GO:0048167 70 0.018
ribonucleotide catabolic process GO:0009261 136 0.018
ribonucleoside metabolic process GO:0009119 174 0.018
response to acid chemical GO:0001101 222 0.018
inorganic ion transmembrane transport GO:0098660 229 0.018
positive regulation of apoptotic process GO:0043065 154 0.018
Mouse
cellular chemical homeostasis GO:0055082 247 0.018
actin filament based process GO:0030029 86 0.018
regulation of dendritic spine morphogenesis GO:0061001 6 0.018
response to nutrient GO:0007584 248 0.018
embryonic pattern specification GO:0009880 1 0.018
regulation of hydrolase activity GO:0051336 143 0.018
regeneration GO:0031099 163 0.018
nucleotide catabolic process GO:0009166 139 0.017
purine nucleoside metabolic process GO:0042278 169 0.017
response to corticosteroid GO:0031960 235 0.017
ribonucleoside triphosphate catabolic process GO:0009203 122 0.017
response to monosaccharide GO:0034284 159 0.017
nucleocytoplasmic transport GO:0006913 48 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
response to extracellular stimulus GO:0009991 380 0.017
cellular ketone metabolic process GO:0042180 51 0.017
transcription from rna polymerase ii promoter GO:0006366 252 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
translation GO:0006412 35 0.017
positive regulation of neuron differentiation GO:0045666 126 0.017
vesicle docking involved in exocytosis GO:0006904 4 0.017
protein autophosphorylation GO:0046777 66 0.017
Human Mouse Rat
single organism biosynthetic process GO:0044711 342 0.017
sensory perception GO:0007600 101 0.017
organic hydroxy compound metabolic process GO:1901615 115 0.016
cerebellar purkinje cell layer morphogenesis GO:0021692 1 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
nucleoside catabolic process GO:0009164 126 0.016
response to nutrient levels GO:0031667 370 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.016
transcription dna templated GO:0006351 377 0.016
proteolysis GO:0006508 175 0.016
regulation of endocytosis GO:0030100 42 0.016
establishment of vesicle localization GO:0051650 31 0.016
maintenance of location GO:0051235 17 0.016
cellular response to nitrogen compound GO:1901699 210 0.016
organophosphate catabolic process GO:0046434 148 0.016
cell part morphogenesis GO:0032990 123 0.016
nucleotide biosynthetic process GO:0009165 98 0.016
positive regulation of synapse maturation GO:0090129 2 0.016
positive regulation of cell death GO:0010942 184 0.015
Mouse
organic cyclic compound catabolic process GO:1901361 175 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
regulation of neuron differentiation GO:0045664 208 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
response to decreased oxygen levels GO:0036293 237 0.015
Rat
negative regulation of developmental process GO:0051093 125 0.015
positive regulation of transcription factor import into nucleus GO:0042993 4 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
regulation of catabolic process GO:0009894 113 0.015
regulation of phosphorylation GO:0042325 248 0.015
intracellular protein transport GO:0006886 79 0.015
eye morphogenesis GO:0048592 4 0.015
response to ketone GO:1901654 182 0.015
positive regulation of nervous system development GO:0051962 178 0.015
single organism reproductive process GO:0044702 297 0.015
Mouse Fly
response to oxidative stress GO:0006979 186 0.014
Rat
regulation of transferase activity GO:0051338 123 0.014
nitrogen compound transport GO:0071705 229 0.014
regulation of dendrite morphogenesis GO:0048814 33 0.014
oxidation reduction process GO:0055114 304 0.014
multi organism reproductive process GO:0044703 262 0.014
Mouse Fly
positive regulation of cell development GO:0010720 176 0.014
mitotic spindle organization GO:0007052 2 0.014
ribonucleoside monophosphate metabolic process GO:0009161 88 0.014
macromolecule catabolic process GO:0009057 58 0.014
cellular component movement GO:0006928 248 0.014
negative regulation of secretion by cell GO:1903531 72 0.014
cell cycle process GO:0022402 57 0.014
Mouse Worm
regulation of kinase activity GO:0043549 117 0.014
multicellular organism reproduction GO:0032504 233 0.013
Fly
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
development of primary sexual characteristics GO:0045137 107 0.013
regulation of calcium ion transport GO:0051924 77 0.013
purine ribonucleoside catabolic process GO:0046130 124 0.013
negative regulation of neuron death GO:1901215 69 0.013
cellular macromolecule catabolic process GO:0044265 29 0.013
aromatic compound catabolic process GO:0019439 168 0.013
purine nucleoside triphosphate catabolic process GO:0009146 122 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
cellular protein catabolic process GO:0044257 19 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
regulation of catalytic activity GO:0050790 304 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
growth GO:0040007 165 0.013
Fly
cation transmembrane transport GO:0098655 263 0.013
regulation of locomotion GO:0040012 148 0.013
embryonic axis specification GO:0000578 1 0.013
immune response GO:0006955 104 0.013
nucleoside phosphate biosynthetic process GO:1901293 102 0.013
cellular response to lipid GO:0071396 201 0.013
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.013
cyclic nucleotide metabolic process GO:0009187 80 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
regulation of mapk cascade GO:0043408 116 0.012
synapse assembly GO:0007416 29 0.012
Fly
cyclic purine nucleotide metabolic process GO:0052652 62 0.012
establishment of organelle localization GO:0051656 37 0.012
negative regulation of signal transduction GO:0009968 83 0.012
Mouse
negative regulation of molecular function GO:0044092 133 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
cellular response to endogenous stimulus GO:0071495 377 0.012
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.012
cell motility GO:0048870 202 0.012
positive regulation of endocytosis GO:0045807 28 0.012
gland development GO:0048732 155 0.012
cerebellar purkinje cell layer development GO:0021680 2 0.012
regulation of protein kinase activity GO:0045859 105 0.012
dephosphorylation GO:0016311 98 0.012
response to hypoxia GO:0001666 231 0.012
Rat
axon regeneration GO:0031103 28 0.012
regulation of synapse organization GO:0050807 19 0.012
synaptic vesicle localization GO:0097479 24 0.012
cellular component morphogenesis GO:0032989 155 0.012
response to glucose GO:0009749 136 0.012
ovulation cycle GO:0042698 67 0.012
response to activity GO:0014823 73 0.012
regulation of bmp signaling pathway GO:0030510 2 0.012
positive regulation of cell motility GO:2000147 97 0.012
regulation of ion transmembrane transporter activity GO:0032412 48 0.012
response to light stimulus GO:0009416 52 0.012
regulation of mrna splicing via spliceosome GO:0048024 3 0.012
blood circulation GO:0008015 183 0.012
mechanoreceptor differentiation GO:0042490 2 0.012
potassium ion homeostasis GO:0055075 2 0.012
sulfur compound metabolic process GO:0006790 70 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
calcineurin nfat signaling cascade GO:0033173 3 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
Fly
regulation of rna biosynthetic process GO:2001141 381 0.011
positive regulation of peptide hormone secretion GO:0090277 50 0.011
digestive system development GO:0055123 41 0.011
regulation of anatomical structure size GO:0090066 135 0.011
negative regulation of phosphate metabolic process GO:0045936 80 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
positive regulation of gene expression GO:0010628 244 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
rna localization GO:0006403 4 0.011
negative regulation of phosphorylation GO:0042326 57 0.011
cytoskeleton dependent cytokinesis GO:0061640 2 0.011
hormone secretion GO:0046879 115 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
spindle organization GO:0007051 2 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
regulation of rna metabolic process GO:0051252 391 0.011
modification dependent protein catabolic process GO:0019941 14 0.011
response to estrogen GO:0043627 232 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
reproductive system development GO:0061458 128 0.011
amide transport GO:0042886 105 0.011
dendrite development GO:0016358 72 0.011
response to ammonium ion GO:0060359 71 0.011
cellular response to extracellular stimulus GO:0031668 73 0.011
mapk cascade GO:0000165 140 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
nuclear transport GO:0051169 49 0.011
transmission of nerve impulse GO:0019226 42 0.011
ion transmembrane transport GO:0034220 365 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
regulation of cellular ketone metabolic process GO:0010565 27 0.010
regulation of secretion by cell GO:1903530 208 0.010
cellular response to biotic stimulus GO:0071216 59 0.010
regulation of cell proliferation GO:0042127 359 0.010
response to vitamin GO:0033273 131 0.010
bmp signaling pathway GO:0030509 4 0.010
positive regulation of transcription dna templated GO:0045893 197 0.010
negative regulation of cellular biosynthetic process GO:0031327 161 0.010
regulation of proteasomal protein catabolic process GO:0061136 4 0.010
negative regulation of transport GO:0051051 136 0.010
negative regulation of secretion GO:0051048 82 0.010
negative regulation of cellular component organization GO:0051129 83 0.010
regulation of immune response GO:0050776 55 0.010
carbohydrate derivative biosynthetic process GO:1901137 124 0.010
gamete generation GO:0007276 124 0.010
Fly
regulation of homeostatic process GO:0032844 101 0.010
organelle organization GO:0006996 266 0.010
Mouse Worm
protein modification by small protein conjugation GO:0032446 31 0.010
actin cytoskeleton organization GO:0030036 73 0.010

Camk2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.023
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023
synucleinopathy DOID:0050890 0 0.019
neurodegenerative disease DOID:1289 0 0.019
parkinson s disease DOID:14330 0 0.012