Rattus norvegicus

148 known processes

Casp1

caspase 1

(Aliases: Il1bc,Ice)

Casp1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
luteolysis GO:0001554 5 0.938
Rat
leukocyte activation GO:0045321 76 0.880
response to other organism GO:0051707 220 0.860
immune system process GO:0002376 204 0.823
immune response GO:0006955 104 0.791
Fly
defense response GO:0006952 194 0.756
Mouse Rat Fly
response to bacterium GO:0009617 200 0.721
cellular response to molecule of bacterial origin GO:0071219 56 0.669
cell activation GO:0001775 97 0.634
positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 0.626
regulation of interleukin 1 beta secretion GO:0050706 3 0.620
myeloid leukocyte activation GO:0002274 36 0.618
positive regulation of immune system process GO:0002684 90 0.618
Fly
response to biotic stimulus GO:0009607 226 0.599
regulation of lymphocyte migration GO:2000401 1 0.557
acute inflammatory response to non antigenic stimulus GO:0002525 2 0.536
Rat
positive regulation of interleukin 1 beta secretion GO:0050718 3 0.530
acute inflammatory response GO:0002526 58 0.517
Rat
response to external biotic stimulus GO:0043207 221 0.504
response to heat GO:0009408 60 0.489
Rat
regulation of cell activation GO:0050865 50 0.436
inflammatory response GO:0006954 150 0.390
Mouse Rat
chemical homeostasis GO:0048878 292 0.364
regulation of t cell migration GO:2000404 1 0.363
response to gamma radiation GO:0010332 24 0.344
Rat
regulation of immune system process GO:0002682 123 0.344
Fly
neurological system process GO:0050877 219 0.319
response to molecule of bacterial origin GO:0002237 194 0.307
response to amino acid GO:0043200 75 0.307
Rat
cellular response to lipopolysaccharide GO:0071222 55 0.306
response to wounding GO:0009611 254 0.304
Mouse Rat
positive regulation of response to stimulus GO:0048584 285 0.301
positive regulation of immune response GO:0050778 42 0.297
Fly
response to lipopolysaccharide GO:0032496 191 0.285
interleukin 1 beta secretion GO:0050702 3 0.283
response to transition metal nanoparticle GO:1990267 122 0.269
Rat
anatomical structure morphogenesis GO:0009653 298 0.263
positive regulation of retinal cell programmed cell death GO:0046670 1 0.248
Rat
cytokine production GO:0001816 61 0.246
metal ion homeostasis GO:0055065 186 0.239
regulation of cell proliferation GO:0042127 359 0.236
positive regulation of cell death GO:0010942 184 0.233
single organismal cell cell adhesion GO:0016337 42 0.228
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.224
positive regulation of interleukin 1 beta production GO:0032731 6 0.220
cation homeostasis GO:0055080 195 0.220
cellular metal ion homeostasis GO:0006875 172 0.215
regulation of apoptotic process GO:0042981 335 0.210
positive regulation of t cell migration GO:2000406 1 0.204
response to inorganic substance GO:0010035 377 0.201
Rat
secretion GO:0046903 307 0.195
wound healing GO:0042060 122 0.194
Rat
positive regulation of leukocyte activation GO:0002696 30 0.191
anatomical structure formation involved in morphogenesis GO:0048646 83 0.183
positive regulation of apoptotic process GO:0043065 154 0.180
cytosolic calcium ion homeostasis GO:0051480 140 0.179
homeostatic process GO:0042592 331 0.178
positive regulation of cell motility GO:2000147 97 0.177
positive regulation of t cell mediated cytotoxicity GO:0001916 4 0.174
response to temperature stimulus GO:0009266 94 0.167
Rat
positive regulation of lymphocyte proliferation GO:0050671 20 0.163
lymphocyte proliferation GO:0046651 29 0.163
calcium ion homeostasis GO:0055074 162 0.159
negative regulation of response to stimulus GO:0048585 155 0.159
microglial cell activation GO:0001774 14 0.159
regulation of immunoglobulin production GO:0002637 4 0.156
cellular response to organic cyclic compound GO:0071407 202 0.154
Rat
response to metal ion GO:0010038 253 0.153
Rat
positive regulation of isotype switching GO:0045830 1 0.152
macromolecular complex assembly GO:0065003 273 0.152
Rat
immune response regulating signaling pathway GO:0002764 19 0.151
b cell activation involved in immune response GO:0002312 1 0.147
regulation of adaptive immune response GO:0002819 8 0.146
response to estradiol GO:0032355 164 0.146
Rat
positive regulation of leukocyte mediated immunity GO:0002705 13 0.145
cellular response to external stimulus GO:0071496 118 0.144
Human
positive regulation of programmed cell death GO:0043068 157 0.140
intracellular signal transduction GO:0035556 314 0.137
Human Mouse Rat
innate immune response GO:0045087 35 0.136
Fly
positive regulation of humoral immune response GO:0002922 2 0.136
Fly
programmed cell death GO:0012501 392 0.135
regulation of leukocyte migration GO:0002685 24 0.134
inflammatory cell apoptotic process GO:0006925 5 0.132
lymphocyte activation GO:0046649 43 0.131
positive regulation of multicellular organismal process GO:0051240 387 0.127
carboxylic acid metabolic process GO:0019752 289 0.126
t cell activation GO:0042110 29 0.123
cell type specific apoptotic process GO:0097285 134 0.123
Rat
response to antibiotic GO:0046677 39 0.122
Rat
response to hypoxia GO:0001666 231 0.120
g protein coupled receptor signaling pathway GO:0007186 242 0.120
leukocyte proliferation GO:0070661 29 0.120
cytokine secretion GO:0050663 15 0.119
tube development GO:0035295 89 0.119
positive regulation of immunoglobulin production GO:0002639 4 0.117
icosanoid metabolic process GO:0006690 38 0.116
negative regulation of homeostatic process GO:0032845 47 0.116
response to oxidative stress GO:0006979 186 0.116
Rat
regulation of programmed cell death GO:0043067 341 0.115
cellular response to biotic stimulus GO:0071216 59 0.115
cellular calcium ion homeostasis GO:0006874 160 0.115
positive regulation of cell activation GO:0050867 34 0.114
hormone secretion GO:0046879 115 0.114
cellular response to lipid GO:0071396 201 0.113
positive regulation of cell migration GO:0030335 96 0.112
positive regulation of interleukin 1 secretion GO:0050716 3 0.109
neuron death GO:0070997 127 0.109
Rat
locomotion GO:0040011 237 0.108
negative regulation of chemotaxis GO:0050922 5 0.107
apoptotic process GO:0006915 381 0.106
response to toxic substance GO:0009636 133 0.105
regulation of phosphate metabolic process GO:0019220 349 0.104
regulation of system process GO:0044057 208 0.102
negative regulation of cell killing GO:0031342 5 0.101
immune response activating signal transduction GO:0002757 15 0.100
positive regulation of locomotion GO:0040017 102 0.100
cell cell signaling GO:0007267 335 0.099
regulation of retinal cell programmed cell death GO:0046668 1 0.097
Rat
regulation of immune effector process GO:0002697 32 0.096
Fly
regulation of signal transduction GO:0009966 318 0.096
Human Mouse
defense response to virus GO:0051607 9 0.094
Fly
regulation of cellular ketone metabolic process GO:0010565 27 0.090
positive regulation of leukocyte proliferation GO:0070665 20 0.090
multi organism reproductive process GO:0044703 262 0.090
Fly
positive regulation of lymphocyte migration GO:2000403 1 0.089
aging GO:0007568 241 0.089
Rat
divalent metal ion transport GO:0070838 132 0.088
positive regulation of response to external stimulus GO:0032103 51 0.088
Fly
positive regulation of b cell mediated immunity GO:0002714 2 0.087
protein transport GO:0015031 132 0.086
release of sequestered calcium ion into cytosol GO:0051209 25 0.086
regulation of release of sequestered calcium ion into cytosol GO:0051279 18 0.085
response to hydrogen peroxide GO:0042542 89 0.083
Rat
rna metabolic process GO:0016070 406 0.082
chemotaxis GO:0006935 66 0.081
activation of immune response GO:0002253 26 0.081
positive regulation of cell proliferation GO:0008284 249 0.081
positive regulation of smooth muscle cell migration GO:0014911 27 0.081
regulation of immune response GO:0050776 55 0.080
Fly
response to decreased oxygen levels GO:0036293 237 0.080
regulation of cellular localization GO:0060341 263 0.080
t cell tolerance induction GO:0002517 3 0.079
response to ionizing radiation GO:0010212 59 0.078
Rat
regulation of response to stress GO:0080134 126 0.078
Mouse Fly
regulation of immunoglobulin mediated immune response GO:0002889 2 0.075
positive regulation of transport GO:0051050 245 0.075
leukocyte activation involved in immune response GO:0002366 16 0.074
negative regulation of phosphorus metabolic process GO:0010563 80 0.074
protein complex biogenesis GO:0070271 263 0.074
Rat
cellular response to organonitrogen compound GO:0071417 197 0.074
leukocyte cell cell adhesion GO:0007159 4 0.072
macromolecule localization GO:0033036 252 0.071
cellular divalent inorganic cation homeostasis GO:0072503 162 0.070
regulation of b cell mediated immunity GO:0002712 2 0.070
positive regulation of immunoglobulin mediated immune response GO:0002891 2 0.070
biological adhesion GO:0022610 110 0.070
cell activation involved in immune response GO:0002263 16 0.069
tissue development GO:0009888 252 0.066
Rat
divalent inorganic cation homeostasis GO:0072507 165 0.066
leukocyte mediated immunity GO:0002443 28 0.066
regulation of secretion by cell GO:1903530 208 0.066
acute phase response GO:0006953 20 0.066
negative regulation of multicellular organismal process GO:0051241 203 0.065
protein complex subunit organization GO:0071822 302 0.065
Rat
protein complex assembly GO:0006461 263 0.065
Rat
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 3 0.064
positive regulation of secretion GO:0051047 140 0.063
regulation of leukocyte activation GO:0002694 45 0.063
histamine production involved in inflammatory response GO:0002349 3 0.063
cell projection organization GO:0030030 302 0.063
cellular ion homeostasis GO:0006873 184 0.062
positive regulation of protein metabolic process GO:0051247 178 0.062
Rat Fly
sequestering of calcium ion GO:0051208 8 0.061
positive regulation of protein phosphorylation GO:0001934 135 0.060
myoblast fusion GO:0007520 2 0.060
positive regulation of dna recombination GO:0045911 1 0.060
cellular response to stress GO:0033554 269 0.060
Rat
positive regulation of leukocyte migration GO:0002687 21 0.059
cellular response to nitrogen compound GO:1901699 210 0.059
neutrophil apoptotic process GO:0001781 4 0.059
positive regulation of secretion by cell GO:1903532 128 0.058
cation transport GO:0006812 382 0.058
cellular chemical homeostasis GO:0055082 247 0.058
ion homeostasis GO:0050801 212 0.058
positive regulation of signaling GO:0023056 270 0.057
Human Mouse
mononuclear cell proliferation GO:0032943 29 0.056
regulation of response to external stimulus GO:0032101 106 0.056
Mouse Fly
positive regulation of leukocyte chemotaxis GO:0002690 10 0.055
immune response regulating cell surface receptor signaling pathway GO:0002768 10 0.054
response to vitamin GO:0033273 131 0.054
catabolic process GO:0009056 351 0.054
Mouse
regulation of mononuclear cell proliferation GO:0032944 26 0.054
positive regulation of phosphorylation GO:0042327 177 0.054
secretion by cell GO:0032940 248 0.054
lymphocyte mediated immunity GO:0002449 14 0.054
cellular component biogenesis GO:0044085 368 0.054
Rat
establishment of protein localization GO:0045184 141 0.053
cellular response to endogenous stimulus GO:0071495 377 0.053
regulation of cell development GO:0060284 263 0.053
Rat
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 2 0.053
monocarboxylic acid metabolic process GO:0032787 152 0.052
regulation of phosphorylation GO:0042325 248 0.052
response to corticosteroid GO:0031960 235 0.052
Rat
cellular response to oxygen containing compound GO:1901701 386 0.052
calcium ion transport GO:0006816 131 0.052
tolerance induction dependent upon immune response GO:0002461 2 0.052
myeloid cell apoptotic process GO:0033028 6 0.051
nucleoside phosphate metabolic process GO:0006753 283 0.050
response to oxygen levels GO:0070482 265 0.050
forebrain development GO:0030900 98 0.050
Rat
positive regulation of molecular function GO:0044093 230 0.050
Rat Fly
antigen receptor mediated signaling pathway GO:0050851 1 0.049
immunoglobulin mediated immune response GO:0016064 4 0.049
muscle cell differentiation GO:0042692 52 0.049
regulation of cellular amino acid metabolic process GO:0006521 2 0.049
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.049
Fly
purine containing compound metabolic process GO:0072521 253 0.048
negative regulation of sequestering of calcium ion GO:0051283 25 0.048
cellular ketone metabolic process GO:0042180 51 0.048
regulation of leukocyte proliferation GO:0070663 26 0.048
regulation of cell motility GO:2000145 131 0.047
cellular homeostasis GO:0019725 252 0.047
response to vitamin d GO:0033280 34 0.047
response to cytokine GO:0034097 215 0.047
Rat
leukocyte migration GO:0050900 38 0.047
protein oligomerization GO:0051259 191 0.047
Rat
central nervous system development GO:0007417 311 0.046
Rat
midgut development GO:0007494 13 0.046
regulation of circadian sleep wake cycle GO:0042749 18 0.046
t cell proliferation GO:0042098 19 0.046
regulation of protein secretion GO:0050708 28 0.046
regulation of behavior GO:0050795 61 0.046
positive regulation of neuron apoptotic process GO:0043525 33 0.046
Rat
regulation of t cell activation GO:0050863 23 0.045
single organism biosynthetic process GO:0044711 342 0.045
single organism cell adhesion GO:0098602 46 0.045
reproductive system development GO:0061458 128 0.044
Rat
regulation of mapk cascade GO:0043408 116 0.044
cell cycle GO:0007049 101 0.044
b cell mediated immunity GO:0019724 4 0.044
regulation of tolerance induction dependent upon immune response GO:0002652 1 0.044
regulation of molecular function GO:0065009 398 0.043
Rat Fly
positive regulation of cell communication GO:0010647 271 0.043
Human Mouse
fatty acid derivative metabolic process GO:1901568 38 0.043
multicellular organismal reproductive process GO:0048609 233 0.043
Rat Fly
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.042
cellular cation homeostasis GO:0030003 180 0.042
positive regulation of behavior GO:0048520 38 0.042
positive regulation of cytokine secretion GO:0050715 9 0.041
regulation of t cell chemotaxis GO:0010819 1 0.041
lymphocyte migration GO:0072676 3 0.041
regulation of secretion GO:0051046 224 0.041
histamine secretion involved in inflammatory response GO:0002441 3 0.040
regulation of platelet activation GO:0010543 2 0.040
positive regulation of t cell proliferation GO:0042102 12 0.040
dna metabolic process GO:0006259 96 0.040
regulation of dna metabolic process GO:0051052 60 0.040
mast cell activation GO:0045576 15 0.040
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 1 0.040
regulation of transferase activity GO:0051338 123 0.040
blood vessel development GO:0001568 69 0.040
regulation of calcium ion transport into cytosol GO:0010522 25 0.039
reproduction GO:0000003 245 0.039
Rat Fly
muscle structure development GO:0061061 87 0.039
regulation of lymphocyte activation GO:0051249 34 0.039
response to nutrient levels GO:0031667 370 0.039
cytoplasmic transport GO:0016482 115 0.039
regulation of cytokine production GO:0001817 56 0.039
retinal cell programmed cell death GO:0046666 1 0.038
Rat
regulation of intracellular signal transduction GO:1902531 218 0.038
Human Mouse
immune effector process GO:0002252 53 0.038
Fly
response to radiation GO:0009314 137 0.038
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.038
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.038
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.038
cardiovascular system development GO:0072358 134 0.038
protein phosphorylation GO:0006468 345 0.038
smooth muscle cell migration GO:0014909 36 0.037
positive regulation of protein secretion GO:0050714 19 0.037
regulation of catalytic activity GO:0050790 304 0.037
Rat Fly
response to nutrient GO:0007584 248 0.037
neuron development GO:0048666 286 0.037
Fly
response to growth factor GO:0070848 189 0.037
regeneration GO:0031099 163 0.037
regulation of cell killing GO:0031341 12 0.036
positive regulation of protein kinase activity GO:0045860 73 0.036
regulation of sequestering of calcium ion GO:0051282 26 0.036
positive regulation of immune effector process GO:0002699 19 0.036
Fly
positive regulation of cellular biosynthetic process GO:0031328 295 0.036
Fly
positive regulation of mapk cascade GO:0043410 92 0.035
regulation of t cell proliferation GO:0042129 17 0.035
response to extracellular stimulus GO:0009991 380 0.034
single organism reproductive process GO:0044702 297 0.034
Rat Fly
cytosolic calcium ion transport GO:0060401 39 0.034
oxoacid metabolic process GO:0043436 290 0.034
blood coagulation GO:0007596 26 0.034
regulation of lymphocyte proliferation GO:0050670 26 0.034
sequestering of metal ion GO:0051238 9 0.034
regulation of defense response GO:0031347 68 0.034
Mouse Fly
positive regulation of tolerance induction dependent upon immune response GO:0002654 1 0.034
aromatic compound catabolic process GO:0019439 168 0.034
t cell migration GO:0072678 2 0.034
regulation of cellular extravasation GO:0002691 2 0.034
negative regulation of metabolic process GO:0009892 331 0.033
vesicle mediated transport GO:0016192 181 0.033
regulation of protein kinase activity GO:0045859 105 0.033
regulation of homeostatic process GO:0032844 101 0.033
regulation of kinase activity GO:0043549 117 0.033
nitrogen compound transport GO:0071705 229 0.033
somatic diversification of immunoglobulins GO:0016445 1 0.033
syncytium formation GO:0006949 4 0.033
defense response to gram positive bacterium GO:0050830 2 0.032
muscle cell migration GO:0014812 36 0.032
regulation of ion homeostasis GO:2000021 63 0.032
sex differentiation GO:0007548 113 0.032
Rat
cellular component movement GO:0006928 248 0.032
neutrophil homeostasis GO:0001780 4 0.032
response to electrical stimulus GO:0051602 56 0.032
proteolysis GO:0006508 175 0.032
Human Zebrafish Mouse Rat Fly
cellular component assembly GO:0022607 360 0.031
Rat
regulation of cell cycle GO:0051726 73 0.031
response to ethanol GO:0045471 162 0.031
Rat
regulation of protein modification process GO:0031399 194 0.031
organic acid metabolic process GO:0006082 292 0.031
somatic cell dna recombination GO:0016444 2 0.031
negative regulation of leukocyte mediated immunity GO:0002704 6 0.031
cellular response to steroid hormone stimulus GO:0071383 93 0.031
organonitrogen compound catabolic process GO:1901565 179 0.031
regulation of body fluid levels GO:0050878 90 0.030
positive regulation of phosphorus metabolic process GO:0010562 262 0.030
memory GO:0007613 54 0.030
reactive nitrogen species metabolic process GO:2001057 1 0.030
gliogenesis GO:0042063 93 0.030
negative regulation of signal transduction GO:0009968 83 0.030
taxis GO:0042330 67 0.030
cellular response to oxidative stress GO:0034599 76 0.030
single organism behavior GO:0044708 130 0.030
neuron differentiation GO:0030182 368 0.030
Rat Fly
regulation of cellular protein metabolic process GO:0032268 267 0.030
Rat Fly
positive regulation of lymphocyte activation GO:0051251 25 0.030
regulation of leukocyte differentiation GO:1902105 20 0.030
regulation of isotype switching GO:0045191 1 0.029
positive regulation of dna metabolic process GO:0051054 39 0.029
heterotypic cell cell adhesion GO:0034113 2 0.029
positive regulation of isotype switching to igg isotypes GO:0048304 1 0.029
olfactory learning GO:0008355 1 0.029
cell adhesion GO:0007155 110 0.029
gamete generation GO:0007276 124 0.029
Fly
positive regulation of cellular protein metabolic process GO:0032270 167 0.029
Rat Fly
positive regulation of map kinase activity GO:0043406 46 0.029
positive regulation of cytokine production GO:0001819 42 0.029
somatic diversification of immunoglobulins involved in immune response GO:0002208 1 0.029
carbohydrate derivative metabolic process GO:1901135 346 0.029
peptidyl tyrosine phosphorylation GO:0018108 72 0.029
multicellular organism reproduction GO:0032504 233 0.029
Rat Fly
cognition GO:0050890 92 0.029
positive regulation of biosynthetic process GO:0009891 319 0.029
Fly
cellular component morphogenesis GO:0032989 155 0.028
head development GO:0060322 247 0.028
Rat
regulation of b cell proliferation GO:0030888 6 0.028
response to ketone GO:1901654 182 0.028
Rat
calcium ion transport into cytosol GO:0060402 38 0.028
respiratory system development GO:0060541 45 0.028
negative regulation of innate immune response GO:0045824 4 0.028
regulation of response to wounding GO:1903034 69 0.028
Mouse
regulation of lymphocyte mediated immunity GO:0002706 11 0.028
defense response to other organism GO:0098542 17 0.028
Fly
cellular response to reactive oxygen species GO:0034614 55 0.027
negative regulation of immune system process GO:0002683 39 0.027
regulation of multicellular organismal development GO:2000026 376 0.027
Rat
signal release GO:0023061 145 0.027
somatic diversification of immune receptors GO:0002200 2 0.027
regulation of smooth muscle cell migration GO:0014910 36 0.027
positive regulation of alpha beta t cell activation GO:0046635 2 0.027
negative regulation of neutrophil apoptotic process GO:0033030 3 0.027
maintenance of location GO:0051235 17 0.027
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 1 0.027
brain development GO:0007420 247 0.027
Rat
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 8 0.027
regulation of protein metabolic process GO:0051246 289 0.027
Rat Fly
adaptive immune response GO:0002250 14 0.027
blood vessel morphogenesis GO:0048514 58 0.027
regulation of map kinase activity GO:0043405 53 0.027
positive regulation of biomineral tissue development GO:0070169 4 0.026
regulation of lymphocyte chemotaxis GO:1901623 1 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.026
regulation of cellular amine metabolic process GO:0033238 8 0.026
regulation of nucleocytoplasmic transport GO:0046822 28 0.026
nucleotide metabolic process GO:0009117 279 0.026
reactive oxygen species metabolic process GO:0072593 37 0.026
peptidyl tyrosine modification GO:0018212 72 0.026
nucleobase containing small molecule metabolic process GO:0055086 316 0.025
positive regulation of innate immune response GO:0045089 11 0.025
Fly
regulation of cytokine secretion GO:0050707 11 0.025
unsaturated fatty acid metabolic process GO:0033559 39 0.025
cellular response to peptide GO:1901653 133 0.025
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.025
leukocyte mediated cytotoxicity GO:0001909 10 0.025
response to peptide GO:1901652 292 0.025
regulation of isotype switching to igg isotypes GO:0048302 1 0.025
regulation of cellular component movement GO:0051270 150 0.025
amide transport GO:0042886 105 0.025
positive regulation of leukocyte degranulation GO:0043302 4 0.025
organophosphate metabolic process GO:0019637 370 0.025
neurotrophin trk receptor signaling pathway GO:0048011 10 0.025
ras protein signal transduction GO:0007265 29 0.025
negative regulation of lymphocyte mediated immunity GO:0002707 5 0.025
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.024
regulation of establishment of protein localization GO:0070201 69 0.024
activation of protein kinase b activity GO:0032148 3 0.024
single organism intracellular transport GO:1902582 166 0.024
regulation of tolerance induction to nonself antigen GO:0002655 1 0.024
cellular response to lipoteichoic acid GO:0071223 1 0.024
response to reactive oxygen species GO:0000302 120 0.024
Rat
regulation of peptide hormone secretion GO:0090276 80 0.024
reproductive process GO:0022414 372 0.024
Rat Fly
indolalkylamine catabolic process GO:0046218 5 0.024
negative regulation of cell communication GO:0010648 158 0.024
positive regulation of cell development GO:0010720 176 0.024
Rat
regulation of peptide secretion GO:0002791 82 0.024
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.024
regulation of cell migration GO:0030334 128 0.024
macrophage activation GO:0042116 15 0.024
cytokine mediated signaling pathway GO:0019221 43 0.024
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 13 0.024
cell adhesion mediated by integrin GO:0033627 1 0.024
granulocyte chemotaxis GO:0071621 15 0.023
regulation of lipid metabolic process GO:0019216 68 0.023
positive regulation of protein modification process GO:0031401 142 0.023
cellular response to cytokine stimulus GO:0071345 127 0.023
divalent inorganic cation transport GO:0072511 134 0.023
regulation of hormone levels GO:0010817 187 0.023
response to hyperoxia GO:0055093 45 0.023
regulation of tolerance induction GO:0002643 2 0.023
sequestering of triglyceride GO:0030730 1 0.023
cell cycle phase transition GO:0044770 21 0.022
muscle system process GO:0003012 115 0.022
response to peptide hormone GO:0043434 278 0.022
growth GO:0040007 165 0.022
positive regulation of nf kappab import into nucleus GO:0042346 2 0.022
fever generation GO:0001660 9 0.022
transcription dna templated GO:0006351 377 0.022
regulation of cell adhesion GO:0030155 52 0.022
cell cycle process GO:0022402 57 0.022
negative regulation of cell matrix adhesion GO:0001953 3 0.022
small gtpase mediated signal transduction GO:0007264 36 0.022
sleep GO:0030431 30 0.022
regulation of vasoconstriction GO:0019229 44 0.022
regulation of calcium ion transport GO:0051924 77 0.022
regulation of interleukin 1 secretion GO:0050704 3 0.022
cellular amino acid metabolic process GO:0006520 107 0.022
response to interferon gamma GO:0034341 20 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.022
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.022
response to iron iii ion GO:0010041 6 0.022
Rat
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.022
positive regulation of developmental process GO:0051094 283 0.021
Rat
tolerance induction to nonself antigen GO:0002462 2 0.021
motor neuron axon guidance GO:0008045 1 0.021
positive regulation of t cell mediated immunity GO:0002711 4 0.021
negative regulation of nucleic acid templated transcription GO:1903507 117 0.021
response to estrogen GO:0043627 232 0.021
Rat
inflammatory response to antigenic stimulus GO:0002437 18 0.021
female pregnancy GO:0007565 122 0.021
purine ribonucleotide metabolic process GO:0009150 227 0.021
platelet aggregation GO:0070527 4 0.021
positive regulation of intracellular signal transduction GO:1902533 138 0.021
Human Mouse
intracellular transport GO:0046907 185 0.021
cellular response to hormone stimulus GO:0032870 247 0.021
negative regulation of signal transduction in absence of ligand GO:1901099 3 0.020
regulation of protein phosphorylation GO:0001932 183 0.020
neuron apoptotic process GO:0051402 88 0.020
Rat
regulation of leukocyte mediated immunity GO:0002703 19 0.020
macromolecule catabolic process GO:0009057 58 0.020
hemostasis GO:0007599 26 0.020
regulation of protein transport GO:0051223 68 0.020
lymphocyte chemotaxis GO:0048247 3 0.020
cell motility GO:0048870 202 0.020
gland development GO:0048732 155 0.020
cellular amine metabolic process GO:0044106 38 0.020
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 6 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
peptidyl amino acid modification GO:0018193 126 0.020
multicellular organismal homeostasis GO:0048871 49 0.020
production of molecular mediator involved in inflammatory response GO:0002532 5 0.020
regulation of hydrolase activity GO:0051336 143 0.019
Rat Fly
cell cell signaling involved in cell fate commitment GO:0045168 2 0.019
regulation of fever generation GO:0031620 6 0.019
positive regulation of t cell chemotaxis GO:0010820 1 0.019
regulation of neutrophil apoptotic process GO:0033029 4 0.019
eosinophil chemotaxis GO:0048245 3 0.019
lipid biosynthetic process GO:0008610 128 0.019
cellular response to abiotic stimulus GO:0071214 85 0.019
Human
protein secretion GO:0009306 34 0.019
immune system development GO:0002520 41 0.019

Casp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
gastrointestinal system cancer DOID:3119 0 0.031
cancer DOID:162 0 0.031
disease of cellular proliferation DOID:14566 0 0.031
organ system cancer DOID:0050686 0 0.031