Rattus norvegicus

90 known processes

Casp12

caspase 12

Casp12 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to bacterium GO:0009617 200 0.548
Rat Fly
response to wounding GO:0009611 254 0.428
Rat
response to estradiol GO:0032355 164 0.382
Rat
response to other organism GO:0051707 220 0.379
Rat Fly
reproductive process GO:0022414 372 0.312
Rat Fly
head development GO:0060322 247 0.302
Rat
response to corticosteroid GO:0031960 235 0.265
Rat
macromolecule localization GO:0033036 252 0.265
Rat
response to biotic stimulus GO:0009607 226 0.254
Rat Fly
regulation of programmed cell death GO:0043067 341 0.224
protein complex subunit organization GO:0071822 302 0.218
Rat
positive regulation of apoptotic process GO:0043065 154 0.203
development of primary sexual characteristics GO:0045137 107 0.194
Rat
positive regulation of cell proliferation GO:0008284 249 0.187
response to external biotic stimulus GO:0043207 221 0.169
Rat Fly
positive regulation of multicellular organismal process GO:0051240 387 0.162
Rat
response to mechanical stimulus GO:0009612 134 0.157
central nervous system development GO:0007417 311 0.155
Rat
liver development GO:0001889 90 0.149
immune system process GO:0002376 204 0.146
Rat Fly
response to cytokine GO:0034097 215 0.144
Rat
positive regulation of interleukin 1 beta secretion GO:0050718 3 0.139
Rat
apoptotic process GO:0006915 381 0.131
cytokine production GO:0001816 61 0.130
Rat
regulation of immune system process GO:0002682 123 0.129
Fly
multi organism reproductive process GO:0044703 262 0.126
Fly
reproductive system development GO:0061458 128 0.126
Rat
regulation of cellular component organization GO:0051128 368 0.123
programmed cell death GO:0012501 392 0.123
protein localization GO:0008104 191 0.121
Rat
response to acid chemical GO:0001101 222 0.120
Rat
positive regulation of response to stimulus GO:0048584 285 0.120
Rat Fly
cellular response to endogenous stimulus GO:0071495 377 0.119
tissue development GO:0009888 252 0.118
Rat
positive regulation of interleukin 1 secretion GO:0050716 3 0.113
Rat
interleukin 6 production GO:0032635 12 0.112
defense response GO:0006952 194 0.108
Rat Fly
positive regulation of cell death GO:0010942 184 0.106
secretion GO:0046903 307 0.106
Rat
brain development GO:0007420 247 0.105
Rat
regulation of interleukin 1 beta secretion GO:0050706 3 0.104
Rat
locomotion GO:0040011 237 0.104
macromolecular complex subunit organization GO:0043933 339 0.102
Rat
regulation of signal transduction GO:0009966 318 0.102
regulation of response to stress GO:0080134 126 0.101
Fly
regulation of apoptotic process GO:0042981 335 0.100
response to lipopolysaccharide GO:0032496 191 0.098
Rat
cellular response to steroid hormone stimulus GO:0071383 93 0.097
cellular response to lipid GO:0071396 201 0.097
regulation of cytokine production GO:0001817 56 0.097
Rat
developmental process involved in reproduction GO:0003006 159 0.096
Rat Fly
establishment of protein localization GO:0045184 141 0.094
Rat
response to temperature stimulus GO:0009266 94 0.093
protein complex assembly GO:0006461 263 0.092
Rat
positive regulation of programmed cell death GO:0043068 157 0.092
regulation of interleukin 6 production GO:0032675 12 0.091
neuron development GO:0048666 286 0.090
Fly
forebrain development GO:0030900 98 0.088
Rat
response to estrogen GO:0043627 232 0.088
Rat
response to molecule of bacterial origin GO:0002237 194 0.087
Rat
gland development GO:0048732 155 0.086
regulation of response to wounding GO:1903034 69 0.083
innate immune response GO:0045087 35 0.083
Fly
regulation of rna biosynthetic process GO:2001141 381 0.082
regulation of intracellular signal transduction GO:1902531 218 0.082
cell type specific apoptotic process GO:0097285 134 0.081
Rat
secretion by cell GO:0032940 248 0.080
Rat
response to glucocorticoid GO:0051384 223 0.080
Rat
multicellular organism reproduction GO:0032504 233 0.079
Rat Fly
intracellular signal transduction GO:0035556 314 0.079
Rat
regulation of protein metabolic process GO:0051246 289 0.078
cell projection organization GO:0030030 302 0.077
cellular component assembly GO:0022607 360 0.076
Rat
cellular chemical homeostasis GO:0055082 247 0.076
regulation of cellular protein metabolic process GO:0032268 267 0.075
positive regulation of cell communication GO:0010647 271 0.075
cellular response to oxygen containing compound GO:1901701 386 0.072
leukocyte activation GO:0045321 76 0.072
Rat
response to amino acid GO:0043200 75 0.072
Rat
cellular component movement GO:0006928 248 0.071
regulation of multicellular organismal development GO:2000026 376 0.071
Rat
cellular response to cytokine stimulus GO:0071345 127 0.071
interleukin 1 secretion GO:0050701 3 0.071
Rat
cellular response to hormone stimulus GO:0032870 247 0.070
cellular response to organic cyclic compound GO:0071407 202 0.069
Rat
cellular catabolic process GO:0044248 295 0.069
positive regulation of cellular component organization GO:0051130 200 0.068
rna metabolic process GO:0016070 406 0.068
regulation of cell motility GO:2000145 131 0.067
transcription dna templated GO:0006351 377 0.067
macromolecular complex assembly GO:0065003 273 0.065
Rat
response to metal ion GO:0010038 253 0.065
tumor necrosis factor biosynthetic process GO:0042533 1 0.065
cell activation GO:0001775 97 0.065
Rat
hepaticobiliary system development GO:0061008 90 0.063
regulation of cell differentiation GO:0045595 320 0.063
Rat
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.063
reproductive structure development GO:0048608 128 0.063
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.063
female gonad development GO:0008585 53 0.062
Rat
regulation of cell proliferation GO:0042127 359 0.062
protein transport GO:0015031 132 0.062
Rat
female sex differentiation GO:0046660 59 0.061
Rat
single organism reproductive process GO:0044702 297 0.060
Rat Fly
protein oligomerization GO:0051259 191 0.060
Rat
response to decreased oxygen levels GO:0036293 237 0.059
cellular response to lipoteichoic acid GO:0071223 1 0.059
immune response GO:0006955 104 0.059
Fly
female pregnancy GO:0007565 122 0.059
cellular response to stress GO:0033554 269 0.059
positive regulation of retinal cell programmed cell death GO:0046670 1 0.059
Rat
cellular lipid metabolic process GO:0044255 208 0.059
regulation of protein transport GO:0051223 68 0.058
Rat
positive regulation of molecular function GO:0044093 230 0.057
rna biosynthetic process GO:0032774 380 0.057
negative regulation of multicellular organismal process GO:0051241 203 0.055
regulation of catalytic activity GO:0050790 304 0.054
neurological system process GO:0050877 219 0.054
Rat
response to interleukin 1 GO:0070555 55 0.054
signal transduction by phosphorylation GO:0023014 144 0.053
cellular response to biotic stimulus GO:0071216 59 0.053
intracellular transport GO:0046907 185 0.052
regulation of cell activation GO:0050865 50 0.051
cellular homeostasis GO:0019725 252 0.050
regulation of protein phosphorylation GO:0001932 183 0.050
regulation of cell development GO:0060284 263 0.050
Rat
cell cycle GO:0007049 101 0.049
transcription from rna polymerase ii promoter GO:0006366 252 0.049
acute inflammatory response to non antigenic stimulus GO:0002525 2 0.049
Rat
multicellular organismal reproductive process GO:0048609 233 0.049
Rat Fly
single organism intracellular transport GO:1902582 166 0.048
cellular response to molecule of bacterial origin GO:0071219 56 0.048
positive regulation of transport GO:0051050 245 0.048
Rat
regulation of defense response GO:0031347 68 0.047
Fly
luteolysis GO:0001554 5 0.047
Rat
positive regulation of signaling GO:0023056 270 0.047
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.045
positive regulation of catalytic activity GO:0043085 184 0.044
nucleoside phosphate metabolic process GO:0006753 283 0.044
cellular component biogenesis GO:0044085 368 0.043
Rat
nucleobase containing small molecule metabolic process GO:0055086 316 0.043
positive regulation of protein metabolic process GO:0051247 178 0.042
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.042
gonad development GO:0008406 104 0.042
Rat
regulation of locomotion GO:0040012 148 0.041
cell projection morphogenesis GO:0048858 123 0.041
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.040
Fly
protein phosphorylation GO:0006468 345 0.040
organophosphate metabolic process GO:0019637 370 0.040
regulation of protein localization GO:0032880 81 0.040
Rat
single organism cellular localization GO:1902580 102 0.040
organ morphogenesis GO:0009887 75 0.040
Rat
regulation of membrane potential GO:0042391 110 0.040
regulation of nucleic acid templated transcription GO:1903506 380 0.039
defense response to other organism GO:0098542 17 0.039
Fly
response to vitamin GO:0033273 131 0.038
regulation of molecular function GO:0065009 398 0.038
organ regeneration GO:0031100 101 0.038
positive regulation of response to external stimulus GO:0032103 51 0.038
Fly
microglial cell activation GO:0001774 14 0.037
Rat
eye morphogenesis GO:0048592 4 0.037
Rat
positive regulation of intracellular signal transduction GO:1902533 138 0.037
cellular response to organonitrogen compound GO:0071417 197 0.037
nucleic acid templated transcription GO:0097659 379 0.037
sequestering of calcium ion GO:0051208 8 0.037
positive regulation of gene expression GO:0010628 244 0.037
response to ketone GO:1901654 182 0.037
Rat
response to peptide GO:1901652 292 0.037
purine containing compound metabolic process GO:0072521 253 0.037
sexual reproduction GO:0019953 148 0.036
Fly
regulation of cellular localization GO:0060341 263 0.036
Rat
positive regulation of defense response GO:0031349 37 0.036
Fly
cell motility GO:0048870 202 0.036
positive regulation of nervous system development GO:0051962 178 0.036
sex differentiation GO:0007548 113 0.036
Rat
regulation of hydrolase activity GO:0051336 143 0.035
cellular protein localization GO:0034613 122 0.035
myeloid leukocyte activation GO:0002274 36 0.035
Rat
positive regulation of protein transport GO:0051222 41 0.034
Rat
multi multicellular organism process GO:0044706 138 0.034
regulation of transcription dna templated GO:0006355 374 0.034
blood vessel morphogenesis GO:0048514 58 0.034
telencephalon development GO:0021537 62 0.034
Rat
regulation of mapk cascade GO:0043408 116 0.034
positive regulation of protein modification process GO:0031401 142 0.034
response to cobalt ion GO:0032025 12 0.034
Rat
regulation of nervous system development GO:0051960 264 0.033
positive regulation of biosynthetic process GO:0009891 319 0.033
Fly
positive regulation of secretion GO:0051047 140 0.033
Rat
positive regulation of i kappab kinase nf kappab signaling GO:0043123 8 0.033
cellular response to lipopolysaccharide GO:0071222 55 0.033
cellular response to acid chemical GO:0071229 75 0.033
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.033
protein complex biogenesis GO:0070271 263 0.032
Rat
response to peptide hormone GO:0043434 278 0.032
response to oxygen levels GO:0070482 265 0.032
nucleotide metabolic process GO:0009117 279 0.032
nitrogen compound transport GO:0071705 229 0.032
positive regulation of phosphorus metabolic process GO:0010562 262 0.032
catabolic process GO:0009056 351 0.031
regulation of protein serine threonine kinase activity GO:0071900 64 0.031
regulation of transferase activity GO:0051338 123 0.031
regulation of establishment of protein localization GO:0070201 69 0.031
Rat
response to oxidative stress GO:0006979 186 0.031
Rat
neuron projection development GO:0031175 273 0.031
cellular response to growth factor stimulus GO:0071363 162 0.031
interleukin 1 production GO:0032612 11 0.031
Rat
regulation of anatomical structure morphogenesis GO:0022603 141 0.031
Rat
cytokine biosynthetic process GO:0042089 3 0.030
positive regulation of leukocyte activation GO:0002696 30 0.030
ribonucleotide metabolic process GO:0009259 231 0.030
positive regulation of signal transduction GO:0009967 175 0.030
synaptic transmission GO:0007268 235 0.030
positive regulation of homeostatic process GO:0032846 49 0.030
positive regulation of cytokine production GO:0001819 42 0.030
Rat
positive regulation of developmental process GO:0051094 283 0.030
Rat
interleukin 12 production GO:0032615 3 0.030
response to inorganic substance GO:0010035 377 0.030
organic acid metabolic process GO:0006082 292 0.030
blood coagulation GO:0007596 26 0.029
regulation of cell migration GO:0030334 128 0.029
immune effector process GO:0002252 53 0.029
Fly
homeostatic process GO:0042592 331 0.029
oxoacid metabolic process GO:0043436 290 0.029
localization of cell GO:0051674 202 0.029
regulation of inflammatory response GO:0050727 48 0.029
positive regulation of cell development GO:0010720 176 0.029
Rat
aging GO:0007568 241 0.029
regeneration GO:0031099 163 0.029
neuron differentiation GO:0030182 368 0.029
Rat Fly
positive regulation of transcription factor import into nucleus GO:0042993 4 0.029
regulation of protein modification process GO:0031399 194 0.029
negative regulation of cell death GO:0060548 229 0.029
Fly
organic substance catabolic process GO:1901575 316 0.028
positive regulation of phosphorylation GO:0042327 177 0.028
regulation of neurogenesis GO:0050767 247 0.028
ribonucleoside metabolic process GO:0009119 174 0.028
pallium development GO:0021543 42 0.028
Rat
coagulation GO:0050817 28 0.028
regulation of map kinase activity GO:0043405 53 0.028
mapk cascade GO:0000165 140 0.027
positive regulation of mapk cascade GO:0043410 92 0.027
positive regulation of neurogenesis GO:0050769 165 0.027
response to transition metal nanoparticle GO:1990267 122 0.027
cell adhesion GO:0007155 110 0.027
regulation of response to external stimulus GO:0032101 106 0.027
Fly
positive regulation of interleukin 6 production GO:0032755 8 0.027
muscle contraction GO:0006936 88 0.027
negative regulation of metabolic process GO:0009892 331 0.027
gamete generation GO:0007276 124 0.027
Fly
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.027
cation homeostasis GO:0055080 195 0.027
regulation of phosphate metabolic process GO:0019220 349 0.027
carboxylic acid metabolic process GO:0019752 289 0.026
organelle organization GO:0006996 266 0.026
regulation of secretion by cell GO:1903530 208 0.026
Rat
response to extracellular stimulus GO:0009991 380 0.026
purine nucleotide metabolic process GO:0006163 229 0.026
single organism organelle organization GO:1902589 180 0.026
single organismal cell cell adhesion GO:0016337 42 0.026
cytoplasmic transport GO:0016482 115 0.026
heterocycle catabolic process GO:0046700 167 0.026
limbic system development GO:0021761 38 0.025
Rat
purine nucleoside catabolic process GO:0006152 124 0.025
cellular response to abiotic stimulus GO:0071214 85 0.025
regulation of protein secretion GO:0050708 28 0.025
Rat
regulation of cellular component movement GO:0051270 150 0.025
positive regulation of interleukin 1 beta production GO:0032731 6 0.025
Rat
carbohydrate derivative metabolic process GO:1901135 346 0.024
cellular component morphogenesis GO:0032989 155 0.024
cellular amine metabolic process GO:0044106 38 0.024
anterior posterior pattern specification GO:0009952 1 0.024
response to ethanol GO:0045471 162 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.024
response to hydrogen peroxide GO:0042542 89 0.024
Rat
positive regulation of cell projection organization GO:0031346 111 0.024
cellular amino acid metabolic process GO:0006520 107 0.024
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.024
positive regulation of the force of heart contraction by norepinephrine GO:0003061 1 0.024
glycosyl compound metabolic process GO:1901657 182 0.024
regulation of retinal cell programmed cell death GO:0046668 1 0.023
Rat
multicellular organismal signaling GO:0035637 44 0.023
positive regulation of cellular component movement GO:0051272 102 0.023
sensory perception of pain GO:0019233 73 0.023
response to hypoxia GO:0001666 231 0.023
Rat
positive regulation of locomotion GO:0040017 102 0.023
positive regulation of protein phosphorylation GO:0001934 135 0.023
regulation of interleukin 8 production GO:0032677 2 0.023
neuronal action potential GO:0019228 35 0.022
response to growth factor GO:0070848 189 0.022
cellular response to external stimulus GO:0071496 118 0.022
regulation of leukocyte activation GO:0002694 45 0.022
reproduction GO:0000003 245 0.022
Rat Fly
negative regulation of cellular metabolic process GO:0031324 281 0.022
regulation of immune response GO:0050776 55 0.022
Fly
anatomical structure formation involved in morphogenesis GO:0048646 83 0.022
Rat Fly
regulation of secretion GO:0051046 224 0.022
Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.022
positive regulation of nucleic acid templated transcription GO:1903508 197 0.022
cation transport GO:0006812 382 0.022
b cell activation involved in immune response GO:0002312 1 0.022
chemical homeostasis GO:0048878 292 0.022
positive regulation of cellular biosynthetic process GO:0031328 295 0.021
Fly
cellular metal ion homeostasis GO:0006875 172 0.021
regulation of rna metabolic process GO:0051252 391 0.021
regulation of cell projection organization GO:0031344 175 0.020
regulation of phosphorylation GO:0042325 248 0.020
regulation of immune effector process GO:0002697 32 0.020
Fly
stress activated protein kinase signaling cascade GO:0031098 37 0.020
cellular ketone metabolic process GO:0042180 51 0.020
vesicle mediated transport GO:0016192 181 0.020
axon development GO:0061564 96 0.020
regulation of kinase activity GO:0043549 117 0.020
negative regulation of cell communication GO:0010648 158 0.020
action potential GO:0001508 54 0.020
cytokine secretion GO:0050663 15 0.020
Rat
regulation of protein kinase activity GO:0045859 105 0.020
positive regulation of neuron differentiation GO:0045666 126 0.020
anatomical structure morphogenesis GO:0009653 298 0.020
Rat Fly
ovulation GO:0030728 17 0.020
cellular macromolecule localization GO:0070727 122 0.019
proteolysis GO:0006508 175 0.019
transmission of nerve impulse GO:0019226 42 0.019
development of primary female sexual characteristics GO:0046545 56 0.019
Rat
sensory organ development GO:0007423 74 0.019
Rat
negative regulation of phosphorus metabolic process GO:0010563 80 0.019
defense response to gram negative bacterium GO:0050829 3 0.019
Fly
negative regulation of macromolecule metabolic process GO:0010605 260 0.019
response to activity GO:0014823 73 0.019
positive regulation of transcription dna templated GO:0045893 197 0.019
fatty acid derivative metabolic process GO:1901568 38 0.019
nucleoside metabolic process GO:0009116 179 0.019
positive regulation of rna metabolic process GO:0051254 203 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
positive regulation of response to wounding GO:1903036 34 0.018
respiratory system development GO:0060541 45 0.018
Rat
protein homooligomerization GO:0051260 91 0.018
response to mineralocorticoid GO:0051385 49 0.018
lymphocyte chemotaxis GO:0048247 3 0.018
regulation of coagulation GO:0050818 11 0.018
rhythmic process GO:0048511 156 0.018
Rat
negative regulation of cellular protein metabolic process GO:0032269 106 0.018
positive regulation of inflammatory response GO:0050729 24 0.018
neuron death GO:0070997 127 0.018
Rat
cellular calcium ion homeostasis GO:0006874 160 0.018
axis specification GO:0009798 4 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
carbohydrate derivative catabolic process GO:1901136 147 0.018
regulation of organ morphogenesis GO:2000027 22 0.018
Rat
nucleoside triphosphate metabolic process GO:0009141 144 0.018
regulation of organelle organization GO:0033043 80 0.018
aromatic compound catabolic process GO:0019439 168 0.018
response to retinoic acid GO:0032526 63 0.017
g protein coupled receptor signaling pathway GO:0007186 242 0.017
positive regulation of immune response GO:0050778 42 0.017
Fly
neuron projection morphogenesis GO:0048812 122 0.017
lung development GO:0030324 43 0.017
Rat
positive regulation of cellular component biogenesis GO:0044089 55 0.017
cell migration GO:0016477 197 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
cellular cation homeostasis GO:0030003 180 0.017
intracellular protein transport GO:0006886 79 0.017
positive regulation of nf kappab import into nucleus GO:0042346 2 0.017
regulation of cell cycle GO:0051726 73 0.016
regulation of neuron differentiation GO:0045664 208 0.016
response to radiation GO:0009314 137 0.016
Rat
organic cyclic compound catabolic process GO:1901361 175 0.016
artery smooth muscle contraction GO:0014824 4 0.016
cardiovascular system development GO:0072358 134 0.016
positive regulation of cell motility GO:2000147 97 0.016
regulation of interferon gamma production GO:0032649 3 0.016
protein heterooligomerization GO:0051291 89 0.016
Rat
leukocyte mediated immunity GO:0002443 28 0.016
monocarboxylic acid metabolic process GO:0032787 152 0.016
negative regulation of protein metabolic process GO:0051248 114 0.016
response to tumor necrosis factor GO:0034612 56 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
purine containing compound catabolic process GO:0072523 138 0.016
negative regulation of gene expression GO:0010629 199 0.016
embryonic pattern specification GO:0009880 1 0.016
regulation of system process GO:0044057 208 0.016
positive regulation of t cell migration GO:2000406 1 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
negative regulation of biosynthetic process GO:0009890 168 0.016
chemotaxis GO:0006935 66 0.016
cellular response to fluid shear stress GO:0071498 4 0.016
ovulation cycle process GO:0022602 50 0.016
Rat
positive regulation of map kinase activity GO:0043406 46 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
regulation of cytokine biosynthetic process GO:0042035 3 0.016
response to testosterone GO:0033574 55 0.016
Rat
response to cold GO:0009409 29 0.016
single organism behavior GO:0044708 130 0.015
Rat
regulation of cellular catabolic process GO:0031329 101 0.015
unsaturated fatty acid metabolic process GO:0033559 39 0.015
b cell mediated immunity GO:0019724 4 0.015
positive regulation of immune effector process GO:0002699 19 0.015
Fly
positive regulation of interferon gamma production GO:0032729 2 0.015
positive regulation of neuron death GO:1901216 43 0.015
Rat
response to alkaloid GO:0043279 132 0.015
purine nucleoside triphosphate metabolic process GO:0009144 141 0.015
negative regulation of osteoblast differentiation GO:0045668 2 0.015
regulation of body fluid levels GO:0050878 90 0.015
cellular response to corticosteroid stimulus GO:0071384 69 0.015
wound healing GO:0042060 122 0.015
Rat
urogenital system development GO:0001655 78 0.015
reactive oxygen species metabolic process GO:0072593 37 0.015
negative regulation of molecular function GO:0044092 133 0.015
cellular ion homeostasis GO:0006873 184 0.015
peptide biosynthetic process GO:0043043 3 0.015
Fly
metal ion transport GO:0030001 289 0.015
hippocampus development GO:0021766 30 0.015
Rat
blood circulation GO:0008015 183 0.015
muscle cell differentiation GO:0042692 52 0.015
Rat
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.015
ribonucleoside monophosphate metabolic process GO:0009161 88 0.015
regulation of vasculature development GO:1901342 44 0.015
ovulation cycle GO:0042698 67 0.015
Rat
cellular response to nitrogen compound GO:1901699 210 0.015
amine metabolic process GO:0009308 38 0.014
single organism biosynthetic process GO:0044711 342 0.014
negative regulation of cytokine production GO:0001818 16 0.014
oxidation reduction process GO:0055114 304 0.014
regulation of cellular component biogenesis GO:0044087 86 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.014
Fly
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.014
positive regulation of kinase activity GO:0033674 77 0.014
positive regulation of protein secretion GO:0050714 19 0.014
Rat
ras protein signal transduction GO:0007265 29 0.014
acute inflammatory response GO:0002526 58 0.014
Rat
fatty acid metabolic process GO:0006631 99 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
positive regulation of secretion by cell GO:1903532 128 0.014
Rat
negative regulation of response to external stimulus GO:0032102 37 0.014
cellular response to reactive oxygen species GO:0034614 55 0.014
positive regulation of cytokine biosynthetic process GO:0042108 1 0.014
regulation of interleukin 1 production GO:0032652 11 0.014
Rat
negative regulation of signaling GO:0023057 157 0.014
negative regulation of phosphate metabolic process GO:0045936 80 0.014
smooth muscle cell proliferation GO:0048659 77 0.014
nucleocytoplasmic transport GO:0006913 48 0.014
positive regulation of immunoglobulin production GO:0002639 4 0.014
nucleoside phosphate catabolic process GO:1901292 140 0.014
response to heat GO:0009408 60 0.014
Rat
response to hexose GO:0009746 144 0.014
Rat
sequestering of metal ion GO:0051238 9 0.014
cell part morphogenesis GO:0032990 123 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
Rat
negative regulation of response to stimulus GO:0048585 155 0.014
positive regulation of endothelial cell migration GO:0010595 4 0.014
cellular response to glucocorticoid stimulus GO:0071385 68 0.014
ribonucleotide catabolic process GO:0009261 136 0.014
response to glucose GO:0009749 136 0.014
Rat
muscle structure development GO:0061061 87 0.014
Rat
guanosine containing compound metabolic process GO:1901068 74 0.014
response to carbohydrate GO:0009743 183 0.014
Rat
regulation of neurological system process GO:0031644 43 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
circadian rhythm GO:0007623 88 0.013
Rat
axon ensheathment GO:0008366 40 0.013
muscle system process GO:0003012 115 0.013
response to anoxia GO:0034059 4 0.013
response to nutrient GO:0007584 248 0.013
regulation of leukocyte migration GO:0002685 24 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.013
cytokine mediated signaling pathway GO:0019221 43 0.013
phasic smooth muscle contraction GO:0014821 3 0.013
negative regulation of viral process GO:0048525 4 0.013
salivary gland development GO:0007431 3 0.013
response to insulin GO:0032868 133 0.013
nucleoside phosphate biosynthetic process GO:1901293 102 0.013
skeletal muscle contraction GO:0003009 17 0.013
response to fatty acid GO:0070542 65 0.013
axonogenesis GO:0007409 71 0.013
peptide transport GO:0015833 97 0.013
spermatogenesis GO:0007283 99 0.013
Fly
mononuclear cell proliferation GO:0032943 29 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.013
positive regulation of immune system process GO:0002684 90 0.013
Fly
response to ionizing radiation GO:0010212 59 0.013
Rat
ameboidal type cell migration GO:0001667 26 0.013
regulation of wound healing GO:0061041 14 0.013
regulation of homeostatic process GO:0032844 101 0.013

Casp12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
gastrointestinal system cancer DOID:3119 0 0.069
disease of cellular proliferation DOID:14566 0 0.069
organ system cancer DOID:0050686 0 0.069
cancer DOID:162 0 0.069
nervous system disease DOID:863 0 0.045
disease of anatomical entity DOID:7 0 0.045
intestinal cancer DOID:10155 0 0.036
sensory system disease DOID:0050155 0 0.024
large intestine cancer DOID:5672 0 0.023
colon cancer DOID:219 0 0.023
colorectal cancer DOID:9256 0 0.023
colon carcinoma DOID:1520 0 0.023
eye and adnexa disease DOID:1492 0 0.018
eye disease DOID:5614 0 0.018
retinal disease DOID:5679 0 0.017