Rattus norvegicus

59 known processes

Casp8

caspase 8

Casp8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of retinal cell programmed cell death GO:0046670 1 0.603
Rat
positive regulation of interleukin 1 secretion GO:0050716 3 0.408
Rat
regulation of interleukin 1 beta secretion GO:0050706 3 0.300
Rat
positive regulation of interleukin 1 beta secretion GO:0050718 3 0.232
Rat
regulation of apoptotic process GO:0042981 335 0.223
Rat
regulation of immune system process GO:0002682 123 0.206
Human
vesicle mediated transport GO:0016192 181 0.201
response to hypoxia GO:0001666 231 0.165
Rat
defense response GO:0006952 194 0.164
Rat
regulation of programmed cell death GO:0043067 341 0.157
Rat
macromolecule localization GO:0033036 252 0.151
Rat
regulation of retinal cell programmed cell death GO:0046668 1 0.139
Rat
positive regulation of programmed cell death GO:0043068 157 0.127
Rat
intracellular signal transduction GO:0035556 314 0.127
Human Rat
cellular response to stress GO:0033554 269 0.126
Rat
programmed cell death GO:0012501 392 0.122
myeloid leukocyte activation GO:0002274 36 0.121
Rat
positive regulation of cell communication GO:0010647 271 0.121
Human
inflammatory response GO:0006954 150 0.121
Rat
transcription dna templated GO:0006351 377 0.117
leukocyte activation GO:0045321 76 0.117
Rat
cell type specific apoptotic process GO:0097285 134 0.114
Rat
regulation of neuron death GO:1901214 115 0.112
Rat
immune effector process GO:0002252 53 0.110
apoptotic process GO:0006915 381 0.106
head development GO:0060322 247 0.106
Rat
protein localization GO:0008104 191 0.104
Rat
positive regulation of immune system process GO:0002684 90 0.104
Human
protein complex biogenesis GO:0070271 263 0.100
rna biosynthetic process GO:0032774 380 0.096
immune system process GO:0002376 204 0.094
Human Rat
response to decreased oxygen levels GO:0036293 237 0.092
Rat
macromolecular complex assembly GO:0065003 273 0.090
negative regulation of cell death GO:0060548 229 0.089
acute inflammatory response to non antigenic stimulus GO:0002525 2 0.088
Rat
positive regulation of apoptotic process GO:0043065 154 0.088
Rat
homeostatic process GO:0042592 331 0.088
cellular component assembly GO:0022607 360 0.083
cation transport GO:0006812 382 0.078
regulation of cellular component organization GO:0051128 368 0.077
response to acid chemical GO:0001101 222 0.077
Rat
positive regulation of response to stimulus GO:0048584 285 0.074
Human Rat
brain development GO:0007420 247 0.074
Rat
regulation of nucleic acid templated transcription GO:1903506 380 0.074
positive regulation of signaling GO:0023056 270 0.072
Human
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.071
positive regulation of biosynthetic process GO:0009891 319 0.070
protein complex assembly GO:0006461 263 0.070
regulation of protein metabolic process GO:0051246 289 0.068
Human Rat
positive regulation of catalytic activity GO:0043085 184 0.067
Human Rat
luteolysis GO:0001554 5 0.067
Rat
response to lipopolysaccharide GO:0032496 191 0.067
regulation of signal transduction GO:0009966 318 0.067
Human
positive regulation of signal transduction GO:0009967 175 0.065
Human
regulation of hydrolase activity GO:0051336 143 0.065
Human Rat
regulation of molecular function GO:0065009 398 0.064
Human Rat
response to estradiol GO:0032355 164 0.064
locomotion GO:0040011 237 0.064
reproductive process GO:0022414 372 0.063
Rat
regulation of secretion GO:0051046 224 0.063
Rat
regulation of neuron apoptotic process GO:0043523 83 0.063
Rat
response to inorganic substance GO:0010035 377 0.063
neuron death GO:0070997 127 0.062
Rat
regulation of rna metabolic process GO:0051252 391 0.062
multicellular organismal reproductive process GO:0048609 233 0.062
Rat
wound healing GO:0042060 122 0.062
Rat
positive regulation of secretion by cell GO:1903532 128 0.062
Rat
positive regulation of secretion GO:0051047 140 0.060
Rat
cation homeostasis GO:0055080 195 0.060
regulation of cellular protein metabolic process GO:0032268 267 0.059
Human Rat
cell migration GO:0016477 197 0.058
response to carbohydrate GO:0009743 183 0.057
Rat
positive regulation of molecular function GO:0044093 230 0.057
Human Rat
regulation of secretion by cell GO:1903530 208 0.056
Rat
female gonad development GO:0008585 53 0.055
Rat
macromolecular complex subunit organization GO:0043933 339 0.055
interleukin 1 beta secretion GO:0050702 3 0.054
Rat
sex differentiation GO:0007548 113 0.054
Rat
response to wounding GO:0009611 254 0.053
Rat
rna metabolic process GO:0016070 406 0.053
response to ethanol GO:0045471 162 0.052
protein complex subunit organization GO:0071822 302 0.052
central nervous system development GO:0007417 311 0.051
Rat
positive regulation of transport GO:0051050 245 0.051
Rat
reproduction GO:0000003 245 0.050
Rat
cellular component biogenesis GO:0044085 368 0.050
response to estrogen GO:0043627 232 0.049
multi organism reproductive process GO:0044703 262 0.049
nucleic acid templated transcription GO:0097659 379 0.049
cell activation GO:0001775 97 0.048
Rat
single organism reproductive process GO:0044702 297 0.048
Rat
response to oxidative stress GO:0006979 186 0.047
Rat
positive regulation of developmental process GO:0051094 283 0.046
Human Rat
regulation of rna biosynthetic process GO:2001141 381 0.046
positive regulation of humoral immune response GO:0002922 2 0.045
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.045
response to extracellular stimulus GO:0009991 380 0.045
response to anoxia GO:0034059 4 0.044
Rat
positive regulation of neuron apoptotic process GO:0043525 33 0.043
Rat
positive regulation of gene expression GO:0010628 244 0.043
proteolysis GO:0006508 175 0.043
regulation of interleukin 1 secretion GO:0050704 3 0.043
Rat
nucleoside phosphate metabolic process GO:0006753 283 0.043
cellular response to organic cyclic compound GO:0071407 202 0.043
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.043
positive regulation of protein metabolic process GO:0051247 178 0.042
Human Rat
chemical homeostasis GO:0048878 292 0.042
positive regulation of cell proliferation GO:0008284 249 0.042
neuron development GO:0048666 286 0.041
gland development GO:0048732 155 0.041
cellular homeostasis GO:0019725 252 0.041
positive regulation of cell death GO:0010942 184 0.041
Rat
response to cytokine GO:0034097 215 0.041
Human Rat
regulation of defense response GO:0031347 68 0.041
regulation of catalytic activity GO:0050790 304 0.040
Human Rat
metal ion homeostasis GO:0055065 186 0.040
development of primary sexual characteristics GO:0045137 107 0.040
Rat
regulation of behavior GO:0050795 61 0.039
Rat
regulation of immune response GO:0050776 55 0.039
immune response GO:0006955 104 0.038
metal ion transport GO:0030001 289 0.038
single organism biosynthetic process GO:0044711 342 0.038
response to ionizing radiation GO:0010212 59 0.038
Rat
response to nutrient levels GO:0031667 370 0.038
single organism behavior GO:0044708 130 0.038
Rat
cellular response to endogenous stimulus GO:0071495 377 0.038
microglial cell activation GO:0001774 14 0.037
Rat
response to oxygen levels GO:0070482 265 0.037
Rat
response to mechanical stimulus GO:0009612 134 0.037
Human
divalent inorganic cation homeostasis GO:0072507 165 0.036
regulation of cell migration GO:0030334 128 0.036
cellular ion homeostasis GO:0006873 184 0.036
regulation of transcription dna templated GO:0006355 374 0.035
developmental process involved in reproduction GO:0003006 159 0.035
Rat
ovulation cycle GO:0042698 67 0.035
Rat
regulation of multicellular organismal development GO:2000026 376 0.035
Human Rat
response to external biotic stimulus GO:0043207 221 0.034
cellular metal ion homeostasis GO:0006875 172 0.034
regulation of cell proliferation GO:0042127 359 0.034
learning or memory GO:0007611 90 0.034
Rat
nitrogen compound transport GO:0071705 229 0.034
neuron differentiation GO:0030182 368 0.034
Rat
protein oligomerization GO:0051259 191 0.033
negative regulation of metabolic process GO:0009892 331 0.033
rhythmic process GO:0048511 156 0.033
Rat
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.033
regulation of intracellular signal transduction GO:1902531 218 0.033
Human
cellular component movement GO:0006928 248 0.033
cellular cation homeostasis GO:0030003 180 0.033
regulation of cell differentiation GO:0045595 320 0.033
Human Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.033
circadian sleep wake cycle process GO:0022410 21 0.032
Rat
cellular amino acid metabolic process GO:0006520 107 0.032
negative regulation of programmed cell death GO:0043069 183 0.032
negative regulation of cellular metabolic process GO:0031324 281 0.032
tissue development GO:0009888 252 0.032
Rat
anatomical structure morphogenesis GO:0009653 298 0.032
Rat
positive regulation of rna biosynthetic process GO:1902680 197 0.032
cellular response to lipid GO:0071396 201 0.031
calcium ion homeostasis GO:0055074 162 0.031
localization of cell GO:0051674 202 0.031
regulation of system process GO:0044057 208 0.031
sequestering of calcium ion GO:0051208 8 0.031
regulation of locomotion GO:0040012 148 0.031
reproductive structure development GO:0048608 128 0.031
Rat
multicellular organism reproduction GO:0032504 233 0.030
Rat
regulation of circadian sleep wake cycle sleep GO:0045187 18 0.030
Rat
cellular catabolic process GO:0044248 295 0.030
Human
cellular response to oxygen containing compound GO:1901701 386 0.030
secretion GO:0046903 307 0.030
Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.029
positive regulation of cellular protein metabolic process GO:0032270 167 0.029
Human Rat
positive regulation of rna metabolic process GO:0051254 203 0.029
sensory organ development GO:0007423 74 0.029
Rat
response to transition metal nanoparticle GO:1990267 122 0.029
Rat
leukocyte mediated immunity GO:0002443 28 0.029
positive regulation of immune response GO:0050778 42 0.029
neuron apoptotic process GO:0051402 88 0.029
Rat
response to hydrogen peroxide GO:0042542 89 0.028
Rat
ion homeostasis GO:0050801 212 0.028
protein phosphorylation GO:0006468 345 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
regulation of phosphate metabolic process GO:0019220 349 0.027
response to other organism GO:0051707 220 0.027
positive regulation of transcription dna templated GO:0045893 197 0.027
response to metal ion GO:0010038 253 0.027
regulation of circadian sleep wake cycle GO:0042749 18 0.027
Rat
positive regulation of behavior GO:0048520 38 0.027
Rat
nucleoside monophosphate metabolic process GO:0009123 93 0.027
positive regulation of neuron death GO:1901216 43 0.027
Rat
peptide biosynthetic process GO:0043043 3 0.026
transcription from rna polymerase ii promoter GO:0006366 252 0.026
cellular divalent inorganic cation homeostasis GO:0072503 162 0.026
organophosphate metabolic process GO:0019637 370 0.026
cellular response to steroid hormone stimulus GO:0071383 93 0.026
cellular chemical homeostasis GO:0055082 247 0.026
response to ketone GO:1901654 182 0.026
Rat
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.026
intracellular transport GO:0046907 185 0.026
amide biosynthetic process GO:0043604 10 0.025
eye morphogenesis GO:0048592 4 0.025
Rat
positive regulation of immune effector process GO:0002699 19 0.025
cell projection organization GO:0030030 302 0.025
forebrain development GO:0030900 98 0.025
Rat
cellular amine metabolic process GO:0044106 38 0.025
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.025
gonad development GO:0008406 104 0.025
Rat
response to endoplasmic reticulum stress GO:0034976 10 0.025
Rat
secretion by cell GO:0032940 248 0.025
Rat
single organism catabolic process GO:0044712 283 0.024
response to molecule of bacterial origin GO:0002237 194 0.024
response to radiation GO:0009314 137 0.024
Rat
positive regulation of cell development GO:0010720 176 0.024
Rat
aging GO:0007568 241 0.024
Rat
muscle system process GO:0003012 115 0.024
axis specification GO:0009798 4 0.023
glial cell apoptotic process GO:0034349 8 0.023
Rat
response to cobalt ion GO:0032025 12 0.023
calcium ion transport into cytosol GO:0060402 38 0.023
nucleoside metabolic process GO:0009116 179 0.023
positive regulation of cytokine secretion GO:0050715 9 0.023
Rat
t cell tolerance induction GO:0002517 3 0.023
cell motility GO:0048870 202 0.023
regulation of cell motility GO:2000145 131 0.023
positive regulation of hydrolase activity GO:0051345 86 0.023
Human Rat
carboxylic acid metabolic process GO:0019752 289 0.022
catabolic process GO:0009056 351 0.022
Human
biological adhesion GO:0022610 110 0.022
response to bacterium GO:0009617 200 0.022
positive regulation of t cell mediated cytotoxicity GO:0001916 4 0.022
establishment of protein localization GO:0045184 141 0.022
Rat
cellular response to external stimulus GO:0071496 118 0.022
Human
positive regulation of nucleic acid templated transcription GO:1903508 197 0.021
cell cell signaling GO:0007267 335 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.021
response to glucose GO:0009749 136 0.021
Rat
organelle organization GO:0006996 266 0.021
retinal cell programmed cell death GO:0046666 1 0.021
Rat
behavior GO:0007610 205 0.021
Rat
response to gamma radiation GO:0010332 24 0.021
Rat
negative regulation of biosynthetic process GO:0009890 168 0.021
female sex differentiation GO:0046660 59 0.021
Rat
negative regulation of apoptotic process GO:0043066 181 0.021
protein maturation GO:0051604 68 0.021
Human Rat
cellular response to hormone stimulus GO:0032870 247 0.021
reproductive system development GO:0061458 128 0.020
Rat
acute inflammatory response GO:0002526 58 0.020
Rat
single organism intracellular transport GO:1902582 166 0.020
mapk cascade GO:0000165 140 0.020
amine metabolic process GO:0009308 38 0.020
positive regulation of defense response GO:0031349 37 0.020
cytokine production GO:0001816 61 0.020
Rat
sexual reproduction GO:0019953 148 0.020
organic substance catabolic process GO:1901575 316 0.020
Human
negative regulation of cellular component organization GO:0051129 83 0.020
cellular calcium ion homeostasis GO:0006874 160 0.019
sequestering of metal ion GO:0051238 9 0.019
negative regulation of multicellular organismal process GO:0051241 203 0.019
circadian rhythm GO:0007623 88 0.019
Rat
cytoplasmic transport GO:0016482 115 0.019
positive regulation of intracellular signal transduction GO:1902533 138 0.019
Human
positive regulation of cytokine production GO:0001819 42 0.019
Rat
response to biotic stimulus GO:0009607 226 0.019
regulation of response to stress GO:0080134 126 0.019
midgut development GO:0007494 13 0.019
Rat
carbohydrate derivative metabolic process GO:1901135 346 0.019
gamete generation GO:0007276 124 0.019
response to corticosteroid GO:0031960 235 0.019
Rat
positive regulation of cell differentiation GO:0045597 217 0.019
Human Rat
ion transmembrane transport GO:0034220 365 0.019
cell cycle checkpoint GO:0000075 2 0.019
purine containing compound metabolic process GO:0072521 253 0.019
transmembrane transport GO:0055085 412 0.019
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.019
regulation of response to external stimulus GO:0032101 106 0.019
neuron projection development GO:0031175 273 0.018
neuron projection morphogenesis GO:0048812 122 0.018
cellular response to organonitrogen compound GO:0071417 197 0.018
cell adhesion GO:0007155 110 0.018
regulation of ion transport GO:0043269 245 0.018
organic acid metabolic process GO:0006082 292 0.018
regulation of protein modification process GO:0031399 194 0.018
cytokine secretion GO:0050663 15 0.018
Rat
positive regulation of leukocyte degranulation GO:0043302 4 0.018
positive regulation of leukocyte activation GO:0002696 30 0.018
divalent inorganic cation transport GO:0072511 134 0.018
anatomical structure formation involved in morphogenesis GO:0048646 83 0.018
Rat
interleukin 1 secretion GO:0050701 3 0.018
Rat
response to reactive oxygen species GO:0000302 120 0.018
Rat
response to nutrient GO:0007584 248 0.017
cellular component morphogenesis GO:0032989 155 0.017
gliogenesis GO:0042063 93 0.017
regeneration GO:0031099 163 0.017
nucleoside phosphate catabolic process GO:1901292 140 0.017
negative regulation of macromolecule metabolic process GO:0010605 260 0.017
immune response regulating signaling pathway GO:0002764 19 0.017
neurological system process GO:0050877 219 0.017
Rat
response to amino acid GO:0043200 75 0.017
Rat
negative regulation of innate immune response GO:0045824 4 0.017
regulation of protein secretion GO:0050708 28 0.017
Rat
endocytosis GO:0006897 84 0.017
response to antibiotic GO:0046677 39 0.017
syncytium formation by plasma membrane fusion GO:0000768 3 0.017
Rat
positive regulation of tolerance induction GO:0002645 1 0.017
response to toxic substance GO:0009636 133 0.017
positive regulation of phosphate metabolic process GO:0045937 262 0.017
response to hexose GO:0009746 144 0.016
Rat
positive regulation of phosphorus metabolic process GO:0010562 262 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.016
response to monosaccharide GO:0034284 159 0.016
Rat
signal transduction by phosphorylation GO:0023014 144 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
calcium ion transport GO:0006816 131 0.016
positive regulation of immunoglobulin production GO:0002639 4 0.016
regulation of mapk cascade GO:0043408 116 0.016
regulation of homeostatic process GO:0032844 101 0.016
purine ribonucleoside metabolic process GO:0046128 168 0.016
regulation of peptidase activity GO:0052547 55 0.016
Human Rat
regulation of innate immune response GO:0045088 15 0.016
organ morphogenesis GO:0009887 75 0.016
Rat
activation of cysteine type endopeptidase activity GO:0097202 4 0.016
Human
oligopeptide transport GO:0006857 4 0.016
rhythmic behavior GO:0007622 24 0.016
Rat
leukocyte activation involved in immune response GO:0002366 16 0.015
phospholipid metabolic process GO:0006644 61 0.015
positive regulation of multicellular organismal process GO:0051240 387 0.015
Human Rat
regulation of membrane potential GO:0042391 110 0.015
regulation of cellular component movement GO:0051270 150 0.015
organ regeneration GO:0031100 101 0.015
spermatogenesis GO:0007283 99 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
development of primary female sexual characteristics GO:0046545 56 0.015
Rat
cell cycle GO:0007049 101 0.015
positive regulation of response to external stimulus GO:0032103 51 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
oxoacid metabolic process GO:0043436 290 0.014
hippocampus development GO:0021766 30 0.014
Rat
male gamete generation GO:0048232 99 0.014
response to insulin GO:0032868 133 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
regulation of cell projection organization GO:0031344 175 0.014
response to growth factor GO:0070848 189 0.014
signal release GO:0023061 145 0.014
regulation of neurogenesis GO:0050767 247 0.014
heterocycle catabolic process GO:0046700 167 0.014
regulation of protein kinase activity GO:0045859 105 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
regulation of hormone levels GO:0010817 187 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.014
positive regulation of cellular component movement GO:0051272 102 0.014
negative regulation of molecular function GO:0044092 133 0.014
negative regulation of cell cycle phase transition GO:1901988 4 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.014
limbic system development GO:0021761 38 0.014
Rat
mitotic spindle organization GO:0007052 2 0.014
organelle localization GO:0051640 55 0.014
myoblast fusion GO:0007520 2 0.014
Rat
cellular ketone metabolic process GO:0042180 51 0.014
nucleobase containing small molecule metabolic process GO:0055086 316 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
cellular response to biotic stimulus GO:0071216 59 0.013
lens development in camera type eye GO:0002088 13 0.013
Rat
erythrocyte differentiation GO:0030218 1 0.013
cell chemotaxis GO:0060326 31 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
female pregnancy GO:0007565 122 0.013
circulatory system process GO:0003013 183 0.013
circadian sleep wake cycle GO:0042745 23 0.013
Rat
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.013
b cell mediated immunity GO:0019724 4 0.013
meiotic cell cycle process GO:1903046 3 0.013
protein autophosphorylation GO:0046777 66 0.013
growth GO:0040007 165 0.013
positive regulation of protein phosphorylation GO:0001934 135 0.013
regulation of phosphorylation GO:0042325 248 0.013
positive regulation of circadian sleep wake cycle sleep GO:0045938 9 0.013
Rat
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
ras protein signal transduction GO:0007265 29 0.012
chemotaxis GO:0006935 66 0.012
cell morphogenesis GO:0000902 142 0.012
single organism cell adhesion GO:0098602 46 0.012
divalent metal ion transport GO:0070838 132 0.012
response to vitamin GO:0033273 131 0.012
hepaticobiliary system development GO:0061008 90 0.012
myeloid cell activation involved in immune response GO:0002275 13 0.012
muscle structure development GO:0061061 87 0.012
Rat
regulation of nervous system development GO:0051960 264 0.012
positive regulation of protein modification process GO:0031401 142 0.012
response to nicotine GO:0035094 51 0.012
Rat
response to iron iii ion GO:0010041 6 0.012
Rat
anion transport GO:0006820 178 0.012
regulation of cell development GO:0060284 263 0.012
Rat
defense response to gram negative bacterium GO:0050829 3 0.012
response to alkaloid GO:0043279 132 0.012
Rat
response to testosterone GO:0033574 55 0.012
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.012
regulation of anatomical structure size GO:0090066 135 0.012
regulation of cell adhesion GO:0030155 52 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
cytosolic calcium ion transport GO:0060401 39 0.012
cell activation involved in immune response GO:0002263 16 0.012
regulation of cellular localization GO:0060341 263 0.012
Rat
positive regulation of neurogenesis GO:0050769 165 0.012
single organism membrane organization GO:0044802 74 0.012
developmental programmed cell death GO:0010623 2 0.012
Rat
positive regulation of mapk cascade GO:0043410 92 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
regulation of immune effector process GO:0002697 32 0.012
cognition GO:0050890 92 0.012
Rat
cell morphogenesis involved in differentiation GO:0000904 119 0.012
circadian sleep wake cycle sleep GO:0050802 21 0.012
Rat
protein heterooligomerization GO:0051291 89 0.012
peptide metabolic process GO:0006518 32 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
single organism cellular localization GO:1902580 102 0.011
apoptotic signaling pathway GO:0097190 27 0.011
Human
regulation of proteolysis GO:0030162 66 0.011
Human Rat
spindle organization GO:0007051 2 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
respiratory system development GO:0060541 45 0.011
Rat
positive regulation of tolerance induction dependent upon immune response GO:0002654 1 0.011
regulation of kinase activity GO:0043549 117 0.011
cellular lipid metabolic process GO:0044255 208 0.011
innate immune response GO:0045087 35 0.011
regulation of leukocyte activation GO:0002694 45 0.011
cellular response to extracellular stimulus GO:0031668 73 0.011
regulation of transferase activity GO:0051338 123 0.011
dna metabolic process GO:0006259 96 0.011
camera type eye development GO:0043010 48 0.011
Rat
regulation of inflammatory response GO:0050727 48 0.011
embryonic pattern specification GO:0009880 1 0.011
regulation of ion homeostasis GO:2000021 63 0.011
regulation of establishment of protein localization GO:0070201 69 0.011
Rat
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.011
negative regulation of phosphate metabolic process GO:0045936 80 0.011
platelet aggregation GO:0070527 4 0.011
negative regulation of transport GO:0051051 136 0.011
antigen receptor mediated signaling pathway GO:0050851 1 0.011
hemopoiesis GO:0030097 34 0.011
Human
response to temperature stimulus GO:0009266 94 0.011
positive regulation of interleukin 1 beta production GO:0032731 6 0.011
Rat
inorganic ion transmembrane transport GO:0098660 229 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
anterior posterior pattern specification GO:0009952 1 0.011
membrane organization GO:0061024 94 0.011
embryonic axis specification GO:0000578 1 0.011
cell cycle process GO:0022402 57 0.011
carbohydrate metabolic process GO:0005975 130 0.011
cellular response to insulin stimulus GO:0032869 81 0.011
muscle contraction GO:0006936 88 0.011
amide transport GO:0042886 105 0.011
activation of protein kinase activity GO:0032147 47 0.011
single organism organelle organization GO:1902589 180 0.010
macrophage activation GO:0042116 15 0.010
Rat
regulation of organelle organization GO:0033043 80 0.010
cellular carbohydrate metabolic process GO:0044262 72 0.010
cation transmembrane transport GO:0098655 263 0.010
positive regulation of protein kinase activity GO:0045860 73 0.010
lymphocyte activation GO:0046649 43 0.010
release of sequestered calcium ion into cytosol GO:0051209 25 0.010
ribonucleoside monophosphate metabolic process GO:0009161 88 0.010
response to peptide hormone GO:0043434 278 0.010
olfactory behavior GO:0042048 2 0.010
regulation of neuron differentiation GO:0045664 208 0.010
peptide transport GO:0015833 97 0.010
regulation of body fluid levels GO:0050878 90 0.010
negative regulation of cellular biosynthetic process GO:0031327 161 0.010
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.010
cellular response to molecule of bacterial origin GO:0071219 56 0.010
erythrocyte homeostasis GO:0034101 2 0.010
negative regulation of signaling GO:0023057 157 0.010
Human
lymphocyte activation involved in immune response GO:0002285 3 0.010
chromosome segregation GO:0007059 2 0.010
regulation of protein phosphorylation GO:0001932 183 0.010

Casp8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
cancer DOID:162 0 0.017
Human
disease of cellular proliferation DOID:14566 0 0.017
Human
organ system cancer DOID:0050686 0 0.017
Human
sensory system disease DOID:0050155 0 0.016