Rattus norvegicus

99 known processes

Cast

calpastatin

(Aliases: MGC108997)

Cast biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein complex assembly GO:0006461 263 0.595
regulation of cellular component movement GO:0051270 150 0.572
macromolecular complex assembly GO:0065003 273 0.469
macromolecular complex subunit organization GO:0043933 339 0.431
protein complex subunit organization GO:0071822 302 0.418
locomotion GO:0040011 237 0.409
synaptic growth at neuromuscular junction GO:0051124 1 0.374
transcription dna templated GO:0006351 377 0.346
regulation of cellular protein metabolic process GO:0032268 267 0.345
response to decreased oxygen levels GO:0036293 237 0.335
neuron differentiation GO:0030182 368 0.331
enzyme linked receptor protein signaling pathway GO:0007167 116 0.327
protein phosphorylation GO:0006468 345 0.326
regulation of protein transport GO:0051223 68 0.325
cellular component biogenesis GO:0044085 368 0.324
programmed cell death GO:0012501 392 0.321
regulation of cellular component organization GO:0051128 368 0.316
cell morphogenesis GO:0000902 142 0.290
cellular response to endogenous stimulus GO:0071495 377 0.285
protein complex biogenesis GO:0070271 263 0.279
macromolecule localization GO:0033036 252 0.278
protein localization GO:0008104 191 0.254
tissue development GO:0009888 252 0.245
cellular response to stress GO:0033554 269 0.245
aging GO:0007568 241 0.223
regulation of protein localization GO:0032880 81 0.219
response to oxygen levels GO:0070482 265 0.219
cellular response to peptide hormone stimulus GO:0071375 120 0.207
cellular response to peptide GO:1901653 133 0.207
cellular component assembly GO:0022607 360 0.205
response to hypoxia GO:0001666 231 0.205
positive regulation of biosynthetic process GO:0009891 319 0.200
vesicle mediated transport GO:0016192 181 0.198
protein transport GO:0015031 132 0.198
response to glucocorticoid GO:0051384 223 0.196
cell motility GO:0048870 202 0.194
endocytosis GO:0006897 84 0.187
single organism organelle organization GO:1902589 180 0.186
response to insulin GO:0032868 133 0.184
positive regulation of molecular function GO:0044093 230 0.183
regulation of secretion by cell GO:1903530 208 0.180
cellular response to hormone stimulus GO:0032870 247 0.178
lens development in camera type eye GO:0002088 13 0.173
nucleoside triphosphate metabolic process GO:0009141 144 0.172
positive regulation of multicellular organismal process GO:0051240 387 0.168
response to cytokine GO:0034097 215 0.167
actin cytoskeleton organization GO:0030036 73 0.162
regulation of cell development GO:0060284 263 0.162
cytoskeleton organization GO:0007010 111 0.152
regulation of phosphate metabolic process GO:0019220 349 0.151
cellular catabolic process GO:0044248 295 0.151
multi organism reproductive process GO:0044703 262 0.150
regulation of cell differentiation GO:0045595 320 0.145
negative regulation of metabolic process GO:0009892 331 0.145
carbohydrate derivative metabolic process GO:1901135 346 0.144
secretion GO:0046903 307 0.143
positive regulation of cell development GO:0010720 176 0.142
organophosphate metabolic process GO:0019637 370 0.140
regulation of cellular localization GO:0060341 263 0.140
establishment of protein localization GO:0045184 141 0.137
positive regulation of catalytic activity GO:0043085 184 0.136
protein autophosphorylation GO:0046777 66 0.136
response to acid chemical GO:0001101 222 0.135
regulation of establishment of protein localization GO:0070201 69 0.135
positive regulation of cell communication GO:0010647 271 0.135
regulation of protein metabolic process GO:0051246 289 0.128
positive regulation of response to stimulus GO:0048584 285 0.127
organophosphate catabolic process GO:0046434 148 0.126
response to estradiol GO:0032355 164 0.126
positive regulation of protein metabolic process GO:0051247 178 0.126
purine nucleoside catabolic process GO:0006152 124 0.126
regulation of apoptotic process GO:0042981 335 0.125
positive regulation of transport GO:0051050 245 0.120
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.120
cellular component movement GO:0006928 248 0.119
actin filament based movement GO:0030048 16 0.119
regulation of protein modification process GO:0031399 194 0.117
positive regulation of cellular protein metabolic process GO:0032270 167 0.117
response to extracellular stimulus GO:0009991 380 0.117
neuron development GO:0048666 286 0.115
reproductive system development GO:0061458 128 0.115
positive regulation of phosphate metabolic process GO:0045937 262 0.114
neuron projection development GO:0031175 273 0.114
cell morphogenesis involved in differentiation GO:0000904 119 0.113
negative regulation of cell death GO:0060548 229 0.111
positive regulation of apoptotic process GO:0043065 154 0.109
peptidyl amino acid modification GO:0018193 126 0.108
regulation of cellular component biogenesis GO:0044087 86 0.108
response to nutrient levels GO:0031667 370 0.105
cell projection organization GO:0030030 302 0.105
cell migration GO:0016477 197 0.105
cellular protein catabolic process GO:0044257 19 0.101
regulation of phosphorus metabolic process GO:0051174 349 0.098
positive regulation of signaling GO:0023056 270 0.098
negative regulation of organ growth GO:0046621 3 0.096
response to estrogen GO:0043627 232 0.093
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.093
regulation of protein phosphorylation GO:0001932 183 0.093
single organism cellular localization GO:1902580 102 0.093
gland development GO:0048732 155 0.093
response to inorganic substance GO:0010035 377 0.092
cellular response to organonitrogen compound GO:0071417 197 0.092
regulation of molecular function GO:0065009 398 0.091
regulation of secretion GO:0051046 224 0.091
regulation of cell motility GO:2000145 131 0.090
regeneration GO:0031099 163 0.090
response to ethanol GO:0045471 162 0.090
actin filament based process GO:0030029 86 0.089
peptidyl tyrosine phosphorylation GO:0018108 72 0.089
regulation of mesenchymal cell proliferation GO:0010464 4 0.089
cellular response to oxygen containing compound GO:1901701 386 0.088
localization of cell GO:0051674 202 0.087
positive regulation of programmed cell death GO:0043068 157 0.087
multicellular organism reproduction GO:0032504 233 0.086
regulation of programmed cell death GO:0043067 341 0.086
nucleoside phosphate catabolic process GO:1901292 140 0.086
reproduction GO:0000003 245 0.085
nucleic acid templated transcription GO:0097659 379 0.084
regulation of kinase activity GO:0043549 117 0.083
response to hydrogen peroxide GO:0042542 89 0.081
cellular component morphogenesis GO:0032989 155 0.080
positive regulation of cell death GO:0010942 184 0.079
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.079
rna metabolic process GO:0016070 406 0.078
response to alkaloid GO:0043279 132 0.078
organelle organization GO:0006996 266 0.077
protein heterooligomerization GO:0051291 89 0.077
response to corticosteroid GO:0031960 235 0.076
organ regeneration GO:0031100 101 0.076
purine nucleoside monophosphate catabolic process GO:0009128 55 0.076
positive regulation of phosphorylation GO:0042327 177 0.075
regulation of cell migration GO:0030334 128 0.075
heart morphogenesis GO:0003007 3 0.075
negative regulation of macromolecule metabolic process GO:0010605 260 0.075
positive regulation of phosphorus metabolic process GO:0010562 262 0.075
atp catabolic process GO:0006200 54 0.075
activation of jak2 kinase activity GO:0042977 2 0.074
multi multicellular organism process GO:0044706 138 0.074
positive regulation of protein modification process GO:0031401 142 0.073
regulation of mapk cascade GO:0043408 116 0.073
regulation of endothelial cell differentiation GO:0045601 4 0.072
homeostatic process GO:0042592 331 0.071
reproductive process GO:0022414 372 0.071
positive regulation of gene expression GO:0010628 244 0.071
regulation of nervous system development GO:0051960 264 0.071
response to hexose GO:0009746 144 0.070
regulation of cell adhesion GO:0030155 52 0.069
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.069
cellular protein complex assembly GO:0043623 44 0.068
multicellular organismal reproductive process GO:0048609 233 0.068
regulation of rna metabolic process GO:0051252 391 0.068
regulation of lymphocyte migration GO:2000401 1 0.067
muscle structure development GO:0061061 87 0.067
regulation of phosphorylation GO:0042325 248 0.067
negative regulation of cellular response to insulin stimulus GO:1900077 11 0.066
transforming growth factor beta receptor complex assembly GO:0007181 2 0.066
single organism carbohydrate metabolic process GO:0044723 118 0.066
receptor mediated endocytosis GO:0006898 42 0.066
regulation of neuron death GO:1901214 115 0.066
negative regulation of programmed cell death GO:0043069 183 0.065
response to peptide hormone GO:0043434 278 0.065
response to peptide GO:1901652 292 0.064
regulation of locomotion GO:0040012 148 0.064
growth GO:0040007 165 0.064
negative regulation of transport GO:0051051 136 0.063
secretion by cell GO:0032940 248 0.062
positive regulation of cell differentiation GO:0045597 217 0.062
ion homeostasis GO:0050801 212 0.061
dendrite development GO:0016358 72 0.061
positive regulation of nervous system development GO:0051962 178 0.061
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.061
response to glucose GO:0009749 136 0.061
ribonucleoside monophosphate metabolic process GO:0009161 88 0.060
heterocycle catabolic process GO:0046700 167 0.060
regulation of cell proliferation GO:0042127 359 0.060
cellular homeostasis GO:0019725 252 0.060
nucleoside triphosphate catabolic process GO:0009143 123 0.060
vasculogenesis GO:0001570 3 0.060
single organism reproductive process GO:0044702 297 0.060
nucleotide metabolic process GO:0009117 279 0.060
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.059
organic acid metabolic process GO:0006082 292 0.059
positive regulation of cellular component organization GO:0051130 200 0.058
regulation of protein secretion GO:0050708 28 0.058
signal transduction by phosphorylation GO:0023014 144 0.058
cell junction assembly GO:0034329 18 0.057
response to monosaccharide GO:0034284 159 0.057
nucleobase containing small molecule metabolic process GO:0055086 316 0.056
purine ribonucleoside catabolic process GO:0046130 124 0.056
nucleoside metabolic process GO:0009116 179 0.055
positive regulation of developmental process GO:0051094 283 0.055
metal ion transport GO:0030001 289 0.055
neuron projection morphogenesis GO:0048812 122 0.055
common partner smad protein phosphorylation GO:0007182 1 0.055
purine nucleoside triphosphate metabolic process GO:0009144 141 0.055
wound healing GO:0042060 122 0.055
ribonucleoside catabolic process GO:0042454 126 0.055
regulation of actin cytoskeleton organization GO:0032956 30 0.054
activation of protein kinase activity GO:0032147 47 0.054
negative regulation of multicellular organismal process GO:0051241 203 0.054
regulation of cell morphogenesis GO:0022604 77 0.053
regulation of catalytic activity GO:0050790 304 0.052
carbohydrate metabolic process GO:0005975 130 0.052
development of primary sexual characteristics GO:0045137 107 0.052
heart development GO:0007507 72 0.052
positive regulation of secretion GO:0051047 140 0.051
positive regulation of cell projection organization GO:0031346 111 0.051
protein o linked glycosylation GO:0006493 2 0.051
anterior posterior pattern specification GO:0009952 1 0.051
response to nutrient GO:0007584 248 0.051
neurological system process GO:0050877 219 0.051
nucleoside monophosphate catabolic process GO:0009125 56 0.050
carboxylic acid metabolic process GO:0019752 289 0.050
receptor metabolic process GO:0043112 18 0.050
regulation of rna biosynthetic process GO:2001141 381 0.050
chemical homeostasis GO:0048878 292 0.050
regulation of cellular catabolic process GO:0031329 101 0.050
regulation of t cell chemotaxis GO:0010819 1 0.050
apoptotic process GO:0006915 381 0.049
regulation of neuron projection development GO:0010975 161 0.049
cellular metal ion homeostasis GO:0006875 172 0.049
purine ribonucleotide metabolic process GO:0009150 227 0.048
ribonucleotide metabolic process GO:0009259 231 0.048
cellular response to lipid GO:0071396 201 0.048
purine nucleoside metabolic process GO:0042278 169 0.048
response to oxidative stress GO:0006979 186 0.048
organic substance catabolic process GO:1901575 316 0.048
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.048
positive regulation of signal transduction GO:0009967 175 0.047
neuron death GO:0070997 127 0.047
purine nucleoside triphosphate catabolic process GO:0009146 122 0.047
cellular ion homeostasis GO:0006873 184 0.046
cell projection morphogenesis GO:0048858 123 0.046
positive regulation of cellular biosynthetic process GO:0031328 295 0.046
cellular response to insulin stimulus GO:0032869 81 0.046
anatomical structure morphogenesis GO:0009653 298 0.046
cellular amino acid metabolic process GO:0006520 107 0.046
response to temperature stimulus GO:0009266 94 0.046
anatomical structure formation involved in morphogenesis GO:0048646 83 0.046
positive regulation of skeletal muscle tissue regeneration GO:0043415 1 0.045
reproductive structure development GO:0048608 128 0.045
negative regulation of cardiac muscle tissue development GO:0055026 3 0.045
single organism biosynthetic process GO:0044711 342 0.045
response to carbohydrate GO:0009743 183 0.044
single organism catabolic process GO:0044712 283 0.044
purine ribonucleoside metabolic process GO:0046128 168 0.044
positive regulation of protein transport GO:0051222 41 0.044
cell cell signaling GO:0007267 335 0.044
cellular nitrogen compound catabolic process GO:0044270 163 0.043
regulation of catabolic process GO:0009894 113 0.043
cation transport GO:0006812 382 0.043
nucleobase containing compound catabolic process GO:0034655 152 0.043
neuron apoptotic process GO:0051402 88 0.042
cellular response to growth factor stimulus GO:0071363 162 0.042
regulation of multicellular organismal development GO:2000026 376 0.042
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.042
nucleoside catabolic process GO:0009164 126 0.042
dna metabolic process GO:0006259 96 0.042
negative regulation of cellular metabolic process GO:0031324 281 0.041
purine nucleotide metabolic process GO:0006163 229 0.041
positive regulation of secretion by cell GO:1903532 128 0.041
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.041
organic cyclic compound catabolic process GO:1901361 175 0.041
response to purine containing compound GO:0014074 126 0.041
regulation of neuron differentiation GO:0045664 208 0.041
multicellular organism growth GO:0035264 1 0.041
positive regulation of neurogenesis GO:0050769 165 0.040
cell adhesion GO:0007155 110 0.040
regulation of anatomical structure morphogenesis GO:0022603 141 0.040
development of primary female sexual characteristics GO:0046545 56 0.039
regulation of cellular ketone metabolic process GO:0010565 27 0.039
gonad development GO:0008406 104 0.039
positive regulation of nucleic acid templated transcription GO:1903508 197 0.039
epithelial cell differentiation GO:0030855 71 0.039
response to metal ion GO:0010038 253 0.039
locomotory exploration behavior GO:0035641 1 0.038
intracellular signal transduction GO:0035556 314 0.038
purine ribonucleotide catabolic process GO:0009154 136 0.038
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.038
transcription from rna polymerase ii promoter GO:0006366 252 0.038
positive regulation of cellular amine metabolic process GO:0033240 3 0.037
rna biosynthetic process GO:0032774 380 0.037
cellular macromolecular complex assembly GO:0034622 58 0.037
regulation of cell projection organization GO:0031344 175 0.037
ovulation cycle GO:0042698 67 0.037
head development GO:0060322 247 0.036
regulation of skeletal muscle tissue regeneration GO:0043416 2 0.036
response to lipopolysaccharide GO:0032496 191 0.036
positive regulation of protein phosphorylation GO:0001934 135 0.036
aromatic compound catabolic process GO:0019439 168 0.035
ribonucleotide catabolic process GO:0009261 136 0.035
cation homeostasis GO:0055080 195 0.035
intracellular transport GO:0046907 185 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.035
dendrite morphogenesis GO:0048813 43 0.035
cellular macromolecule localization GO:0070727 122 0.035
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.034
cognition GO:0050890 92 0.034
central nervous system development GO:0007417 311 0.034
glycosyl compound metabolic process GO:1901657 182 0.034
embryonic skeletal system development GO:0048706 3 0.034
biological adhesion GO:0022610 110 0.034
cellular response to steroid hormone stimulus GO:0071383 93 0.034
catabolic process GO:0009056 351 0.034
cellular protein localization GO:0034613 122 0.034
female gonad development GO:0008585 53 0.034
vasculature development GO:0001944 70 0.034
peptidyl serine phosphorylation GO:0018105 33 0.034
protein oligomerization GO:0051259 191 0.033
amine metabolic process GO:0009308 38 0.033
regulation of intracellular signal transduction GO:1902531 218 0.033
positive regulation of smooth muscle cell migration GO:0014911 27 0.033
response to amino acid GO:0043200 75 0.033
cellular chemical homeostasis GO:0055082 247 0.033
cellular response to organic cyclic compound GO:0071407 202 0.033
memory GO:0007613 54 0.033
intracellular protein transport GO:0006886 79 0.033
cellular amine metabolic process GO:0044106 38 0.032
negative regulation of gene expression GO:0010629 199 0.032
negative regulation of epithelial cell differentiation GO:0030857 5 0.032
cellular response to nitrogen compound GO:1901699 210 0.032
purine containing compound metabolic process GO:0072521 253 0.032
response to toxic substance GO:0009636 133 0.031
regulation of nucleic acid templated transcription GO:1903506 380 0.031
nucleoside phosphate metabolic process GO:0006753 283 0.031
maintenance of location GO:0051235 17 0.031
single organism intracellular transport GO:1902582 166 0.031
proteolysis GO:0006508 175 0.031
positive regulation of transcription dna templated GO:0045893 197 0.031
positive regulation of transferase activity GO:0051347 81 0.030
protein secretion GO:0009306 34 0.030
positive regulation of neuron projection development GO:0010976 99 0.030
gamete generation GO:0007276 124 0.030
female pregnancy GO:0007565 122 0.030
peptidyl serine modification GO:0018209 34 0.030
developmental process involved in reproduction GO:0003006 159 0.030
regulation of cellular amine metabolic process GO:0033238 8 0.030
carbohydrate derivative catabolic process GO:1901136 147 0.029
divalent inorganic cation homeostasis GO:0072507 165 0.029
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.029
single organism behavior GO:0044708 130 0.029
synapse assembly GO:0007416 29 0.029
epithelium development GO:0060429 96 0.029
cellular lipid metabolic process GO:0044255 208 0.029
nucleotide catabolic process GO:0009166 139 0.029
regulation of transcription dna templated GO:0006355 374 0.029
ribonucleoside triphosphate metabolic process GO:0009199 141 0.029
negative regulation of actin filament polymerization GO:0030837 4 0.029
response to transition metal nanoparticle GO:1990267 122 0.028
regulation of cell growth GO:0001558 85 0.028
palate development GO:0060021 2 0.028
purine containing compound catabolic process GO:0072523 138 0.028
protein processing GO:0016485 68 0.028
atp metabolic process GO:0046034 72 0.028
sex differentiation GO:0007548 113 0.028
cellular ketone metabolic process GO:0042180 51 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
blood vessel morphogenesis GO:0048514 58 0.027
negative regulation of cellular protein metabolic process GO:0032269 106 0.027
rhythmic process GO:0048511 156 0.027
positive regulation of growth GO:0045927 55 0.027
cell substrate adhesion GO:0031589 29 0.027
response to external biotic stimulus GO:0043207 221 0.027
axis specification GO:0009798 4 0.027
protein targeting GO:0006605 61 0.027
barbed end actin filament capping GO:0051016 1 0.026
negative regulation of secretion by cell GO:1903531 72 0.026
response to wounding GO:0009611 254 0.026
regulation of vesicle mediated transport GO:0060627 81 0.026
regulation of transferase activity GO:0051338 123 0.026
negative regulation of neuron death GO:1901215 69 0.026
response to fatty acid GO:0070542 65 0.026
positive regulation of cytoplasmic transport GO:1903651 32 0.026
cellular response to corticosteroid stimulus GO:0071384 69 0.026
endocardial cushion development GO:0003197 1 0.025
cell junction organization GO:0034330 21 0.025
brain development GO:0007420 247 0.025
developmental growth GO:0048589 100 0.025
actin filament organization GO:0007015 42 0.025
regulation of signal transduction GO:0009966 318 0.025
positive regulation of protein kinase activity GO:0045860 73 0.025
regulation of growth GO:0040008 105 0.025
protein maturation GO:0051604 68 0.025
nucleoside bisphosphate metabolic process GO:0033865 1 0.025
regulation of neurogenesis GO:0050767 247 0.025
response to reactive oxygen species GO:0000302 120 0.025
neural crest cell development GO:0014032 2 0.025
positive regulation of kinase activity GO:0033674 77 0.025
regulation of anatomical structure size GO:0090066 135 0.025
negative regulation of cardiac muscle tissue growth GO:0055022 3 0.024
response to ionizing radiation GO:0010212 59 0.024
regulation of protein kinase activity GO:0045859 105 0.024
purine nucleotide catabolic process GO:0006195 136 0.024
actin filament depolymerization GO:0030042 3 0.024
negative regulation of cell differentiation GO:0045596 99 0.024
oxoacid metabolic process GO:0043436 290 0.024
actin filament capping GO:0051693 2 0.024
positive regulation of neuron differentiation GO:0045666 126 0.024
response to tumor necrosis factor GO:0034612 56 0.024
regulation of smooth muscle cell proliferation GO:0048660 75 0.024
muscle cell proliferation GO:0033002 84 0.023
regulation of membrane potential GO:0042391 110 0.023
negative regulation of cell communication GO:0010648 158 0.023
organ morphogenesis GO:0009887 75 0.023
ovarian follicle development GO:0001541 31 0.023
regulation of apoptotic signaling pathway GO:2001233 13 0.023
cytoplasmic transport GO:0016482 115 0.023
forebrain development GO:0030900 98 0.023
smooth muscle cell proliferation GO:0048659 77 0.023
positive regulation of rna biosynthetic process GO:1902680 197 0.023
bone development GO:0060348 25 0.023
cell type specific apoptotic process GO:0097285 134 0.022
transforming growth factor beta receptor signaling pathway GO:0007179 18 0.022
circulatory system development GO:0072359 134 0.022
ribonucleoside triphosphate catabolic process GO:0009203 122 0.022
signal release GO:0023061 145 0.022
peptide biosynthetic process GO:0043043 3 0.022
ovulation cycle process GO:0022602 50 0.021
cell growth GO:0016049 104 0.021
protein polymerization GO:0051258 22 0.021
regulation of neuron apoptotic process GO:0043523 83 0.021
leukocyte activation GO:0045321 76 0.021
organonitrogen compound catabolic process GO:1901565 179 0.021
positive regulation of rna metabolic process GO:0051254 203 0.021
metal ion homeostasis GO:0055065 186 0.021
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.021
regulation of response to stress GO:0080134 126 0.021
regulation of lipid metabolic process GO:0019216 68 0.021
tissue regeneration GO:0042246 36 0.021
myoblast fusion GO:0007520 2 0.021
negative regulation of developmental process GO:0051093 125 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.020
positive regulation of developmental growth GO:0048639 29 0.020
regulation of cytoskeleton organization GO:0051493 49 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
ribonucleoside metabolic process GO:0009119 174 0.020
defense response GO:0006952 194 0.020
lipid metabolic process GO:0006629 283 0.020
skeletal muscle tissue regeneration GO:0043403 10 0.020
regulation of dendritic spine morphogenesis GO:0061001 6 0.020
circulatory system process GO:0003013 183 0.019
bmp signaling pathway GO:0030509 4 0.019
mapk cascade GO:0000165 140 0.019
dendritic spine morphogenesis GO:0060997 9 0.019
regulation of peptide hormone secretion GO:0090276 80 0.019
heart formation GO:0060914 1 0.019
regulation of proteolysis GO:0030162 66 0.019
insulin receptor signaling pathway GO:0008286 24 0.019
regulation of actin filament depolymerization GO:0030834 2 0.019
regulation of cardiac muscle tissue growth GO:0055021 12 0.019
calcium ion homeostasis GO:0055074 162 0.019
regulation of sequence specific dna binding transcription factor activity GO:0051090 35 0.019
positive regulation of cell proliferation GO:0008284 249 0.019
protein import GO:0017038 37 0.018
positive regulation of leukocyte degranulation GO:0043302 4 0.018
positive regulation of peptide secretion GO:0002793 52 0.018
cellular calcium ion homeostasis GO:0006874 160 0.018
response to growth factor GO:0070848 189 0.018
positive regulation of intracellular signal transduction GO:1902533 138 0.018
membrane organization GO:0061024 94 0.018
response to ketone GO:1901654 182 0.018
regulation of hormone levels GO:0010817 187 0.018
transmembrane transport GO:0055085 412 0.018
regulation of dna metabolic process GO:0051052 60 0.018
positive regulation of immune system process GO:0002684 90 0.018
urogenital system development GO:0001655 78 0.018
metaphase anaphase transition of cell cycle GO:0044784 1 0.018
negative regulation of signal transduction GO:0009968 83 0.018
regulation of cell cycle GO:0051726 73 0.017
leukocyte differentiation GO:0002521 30 0.017
negative regulation of growth GO:0045926 37 0.017
positive regulation of retinal cell programmed cell death GO:0046670 1 0.017
valine metabolic process GO:0006573 1 0.017
regulation of jak stat cascade GO:0046425 21 0.017
negative regulation of heart growth GO:0061117 3 0.017
negative regulation of actin filament depolymerization GO:0030835 2 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
ribonucleoside monophosphate catabolic process GO:0009158 55 0.017
pathway restricted smad protein phosphorylation GO:0060389 1 0.017
metanephric nephron tubule epithelial cell differentiation GO:0072257 1 0.017
cytokinetic process GO:0032506 1 0.017
reactive oxygen species biosynthetic process GO:1903409 8 0.017
cytokine production GO:0001816 61 0.017
blood circulation GO:0008015 183 0.017
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.017
cell part morphogenesis GO:0032990 123 0.017
positive regulation of interleukin 1 secretion GO:0050716 3 0.016
negative regulation of secretion GO:0051048 82 0.016

Cast disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.046
disease of cellular proliferation DOID:14566 0 0.046
central nervous system disease DOID:331 0 0.035
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.035
organ system cancer DOID:0050686 0 0.024