Rattus norvegicus

23 known processes

Cav2

caveolin 2

(Aliases: MGC72322)

Cav2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ventricular cardiac muscle cell action potential GO:0086005 2 0.998
Rat
negative regulation of heart growth GO:0061117 3 0.891
Rat
positive regulation of microtubule polymerization GO:0031116 5 0.818
Rat
cardiac muscle cell action potential GO:0086001 5 0.803
Rat
sterol transport GO:0015918 6 0.744
Rat
negative regulation of endothelial cell proliferation GO:0001937 5 0.709
negative regulation of cardiac muscle tissue growth GO:0055022 3 0.595
Rat
negative regulation of organ growth GO:0046621 3 0.574
Rat
cholesterol efflux GO:0033344 1 0.545
Rat
cardiac muscle cell action potential involved in contraction GO:0086002 2 0.526
Rat
positive regulation of caveolin mediated endocytosis GO:2001288 2 0.516
Rat
regulation of caveolin mediated endocytosis GO:2001286 2 0.482
Rat
negative regulation of cell growth involved in cardiac muscle cell development GO:0061052 1 0.443
Rat
cholesterol transport GO:0030301 5 0.426
Rat
vascular process in circulatory system GO:0003018 96 0.356
Rat
response to gamma radiation GO:0010332 24 0.251
Rat
negative regulation of potassium ion transmembrane transporter activity GO:1901017 3 0.233
Rat
negative regulation of smooth muscle cell proliferation GO:0048662 21 0.219
Rat
circulatory system process GO:0003013 183 0.207
Rat
regulation of system process GO:0044057 208 0.195
Rat
regulation of blood vessel size GO:0050880 89 0.190
Rat
negative regulation of epithelial cell proliferation GO:0050680 16 0.183
microtubule polymerization or depolymerization GO:0031109 13 0.174
Rat
regulation of cardiac muscle tissue development GO:0055024 12 0.172
Rat
regulation of potassium ion transport GO:0043266 29 0.166
Rat
regulation of striated muscle contraction GO:0006942 21 0.157
Rat
regulation of signal transduction GO:0009966 318 0.155
Rat
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.154
Rat
cation transmembrane transport GO:0098655 263 0.152
Rat
cellular response to stress GO:0033554 269 0.138
Rat
regulation of heart growth GO:0060420 12 0.134
Rat
cellular potassium ion transport GO:0071804 72 0.134
Rat
actin mediated cell contraction GO:0070252 12 0.128
regulation of blood circulation GO:1903522 110 0.125
Rat
cell cell signaling GO:0007267 335 0.124
inorganic ion transmembrane transport GO:0098660 229 0.121
Rat
actin filament based movement GO:0030048 16 0.118
response to mechanical stimulus GO:0009612 134 0.114
Rat
synaptic transmission GO:0007268 235 0.110
carboxylic acid metabolic process GO:0019752 289 0.108
negative regulation of potassium ion transmembrane transport GO:1901380 3 0.102
Rat
response to ionizing radiation GO:0010212 59 0.101
Rat
regulation of molecular function GO:0065009 398 0.099
Rat
negative regulation of muscle hypertrophy GO:0014741 3 0.096
Rat
regulation of cardiac muscle cell contraction GO:0086004 11 0.096
Rat
negative regulation of muscle organ development GO:0048635 8 0.095
Rat
response to wounding GO:0009611 254 0.094
Rat
cardiac cell development GO:0055006 16 0.091
Rat
negative regulation of potassium ion transport GO:0043267 11 0.091
Rat
chemical homeostasis GO:0048878 292 0.090
Rat
intracellular signal transduction GO:0035556 314 0.089
Rat
negative regulation of muscle cell apoptotic process GO:0010656 21 0.087
Rat
organ regeneration GO:0031100 101 0.085
Rat
regulation of microtubule cytoskeleton organization GO:0070507 14 0.085
Rat
negative regulation of nervous system development GO:0051961 79 0.085
Rat
regulation of mapk cascade GO:0043408 116 0.084
Rat
regulation of cell development GO:0060284 263 0.083
Rat
regulation of epithelial cell proliferation GO:0050678 49 0.083
regulation of neuron differentiation GO:0045664 208 0.082
Rat
positive regulation of cell proliferation GO:0008284 249 0.081
Rat
cardiac muscle tissue growth GO:0055017 20 0.081
Rat
cellular protein localization GO:0034613 122 0.080
Rat
positive regulation of signal transduction GO:0009967 175 0.080
Rat
cellular homeostasis GO:0019725 252 0.080
Rat
regulation of neurogenesis GO:0050767 247 0.078
Rat
muscle contraction GO:0006936 88 0.077
microtubule polymerization GO:0046785 9 0.076
Rat
response to extracellular stimulus GO:0009991 380 0.074
Rat
negative regulation of signaling GO:0023057 157 0.074
Rat
negative regulation of transporter activity GO:0032410 13 0.074
Rat
negative regulation of cation channel activity GO:2001258 6 0.073
Rat
maintenance of location GO:0051235 17 0.068
Rat
regulation of ion transport GO:0043269 245 0.068
Rat
muscle cell apoptotic process GO:0010657 30 0.067
Rat
calcium ion homeostasis GO:0055074 162 0.067
Rat
cellular response to mechanical stimulus GO:0071260 48 0.066
Rat
ion transmembrane transport GO:0034220 365 0.065
Rat
metal ion homeostasis GO:0055065 186 0.064
Rat
regulation of muscle system process GO:0090257 79 0.064
Rat
cytoskeleton organization GO:0007010 111 0.063
Rat
positive regulation of cellular component organization GO:0051130 200 0.062
Rat
potassium ion transport GO:0006813 97 0.060
Rat
endothelial cell proliferation GO:0001935 20 0.059
negative regulation of metabolic process GO:0009892 331 0.059
Rat
protein complex assembly GO:0006461 263 0.059
Rat
regulation of smooth muscle cell proliferation GO:0048660 75 0.059
Rat
cell type specific apoptotic process GO:0097285 134 0.058
Rat
aging GO:0007568 241 0.057
Rat
signal transduction by phosphorylation GO:0023014 144 0.057
Rat
regulation of receptor mediated endocytosis GO:0048259 17 0.057
Rat
regulation of multicellular organismal development GO:2000026 376 0.056
Rat
epithelial cell proliferation GO:0050673 54 0.055
negative regulation of cell proliferation GO:0008285 119 0.055
negative regulation of ion transmembrane transport GO:0034766 16 0.054
Rat
regulation of cell proliferation GO:0042127 359 0.054
heart growth GO:0060419 20 0.054
Rat
regulation of cell differentiation GO:0045595 320 0.054
Rat
cellular response to external stimulus GO:0071496 118 0.054
Rat
erk1 and erk2 cascade GO:0070371 48 0.053
Rat
inorganic cation transmembrane transport GO:0098662 202 0.053
Rat
metal ion transport GO:0030001 289 0.053
Rat
cellular calcium ion homeostasis GO:0006874 160 0.053
Rat
negative regulation of cellular metabolic process GO:0031324 281 0.052
Rat
positive regulation of response to stimulus GO:0048584 285 0.052
Rat
cellular metal ion homeostasis GO:0006875 172 0.050
Rat
divalent inorganic cation homeostasis GO:0072507 165 0.050
Rat
developmental growth GO:0048589 100 0.050
Rat
regulation of developmental growth GO:0048638 45 0.049
Rat
maintenance of protein location GO:0045185 7 0.049
Rat
heart contraction GO:0060047 57 0.048
Rat
cation homeostasis GO:0055080 195 0.048
Rat
cardiac muscle contraction GO:0060048 27 0.046
regulation of organelle organization GO:0033043 80 0.046
Rat
negative regulation of phosphorus metabolic process GO:0010563 80 0.045
Rat
negative regulation of mapk cascade GO:0043409 20 0.044
Rat
organic hydroxy compound transport GO:0015850 77 0.044
Rat
negative regulation of signal transduction GO:0009968 83 0.043
Rat
positive regulation of transport GO:0051050 245 0.043
Rat
cardiac muscle cell contraction GO:0086003 10 0.043
regulation of phosphorylation GO:0042325 248 0.043
Rat
regulation of cytoskeleton organization GO:0051493 49 0.042
Rat
cellular amine metabolic process GO:0044106 38 0.041
heart process GO:0003015 57 0.040
Rat
positive regulation of catabolic process GO:0009896 78 0.040
physiological muscle hypertrophy GO:0003298 13 0.039
Rat
negative regulation of ion transport GO:0043271 51 0.039
Rat
cellular ion homeostasis GO:0006873 184 0.037
Rat
regulation of transmembrane transport GO:0034762 122 0.037
Rat
cellular component movement GO:0006928 248 0.036
positive regulation of phosphorus metabolic process GO:0010562 262 0.036
negative regulation of ion transmembrane transporter activity GO:0032413 12 0.034
Rat
amine metabolic process GO:0009308 38 0.033
regulation of cellular ketone metabolic process GO:0010565 27 0.033
muscle system process GO:0003012 115 0.032
Rat
regulation of muscle contraction GO:0006937 53 0.032
Rat
vesicle mediated transport GO:0016192 181 0.032
Rat
positive regulation of epithelial cell proliferation GO:0050679 32 0.032
Rat
negative regulation of erk1 and erk2 cascade GO:0070373 9 0.032
Rat
negative regulation of cell communication GO:0010648 158 0.032
Rat
negative regulation of multicellular organismal process GO:0051241 203 0.031
Rat
regulation of vesicle mediated transport GO:0060627 81 0.031
Rat
regulation of erk1 and erk2 cascade GO:0070372 41 0.031
Rat
cardiac muscle cell development GO:0055013 16 0.030
Rat
negative regulation of neuron differentiation GO:0045665 62 0.030
Rat
positive regulation of endocytosis GO:0045807 28 0.030
Rat
wound healing GO:0042060 122 0.030
Rat
regulation of ion transmembrane transporter activity GO:0032412 48 0.029
Rat
lipid localization GO:0010876 62 0.029
Rat
cellular ketone metabolic process GO:0042180 51 0.029
response to acid chemical GO:0001101 222 0.029
positive regulation of molecular function GO:0044093 230 0.029
transcription dna templated GO:0006351 377 0.028
protein complex biogenesis GO:0070271 263 0.028
Rat
regulation of muscle cell differentiation GO:0051147 22 0.027
Rat
striated muscle contraction GO:0006941 44 0.027
positive regulation of microtubule polymerization or depolymerization GO:0031112 7 0.027
Rat
oxoacid metabolic process GO:0043436 290 0.027
regulation of transporter activity GO:0032409 50 0.027
Rat
negative regulation of growth GO:0045926 37 0.026
Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
organic acid metabolic process GO:0006082 292 0.026
regulation of purine nucleotide metabolic process GO:1900542 115 0.026
positive regulation of signaling GO:0023056 270 0.026
Rat
positive regulation of cell differentiation GO:0045597 217 0.025
smooth muscle cell proliferation GO:0048659 77 0.025
Rat
mapk cascade GO:0000165 140 0.025
Rat
blood circulation GO:0008015 183 0.025
Rat
transcription from rna polymerase ii promoter GO:0006366 252 0.025
action potential GO:0001508 54 0.025
Rat
cellular response to oxygen containing compound GO:1901701 386 0.025
growth GO:0040007 165 0.024
Rat
regulation of membrane potential GO:0042391 110 0.024
Rat
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.024
regulation of protein metabolic process GO:0051246 289 0.024
response to nutrient GO:0007584 248 0.023
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.023
Rat
negative regulation of macromolecule metabolic process GO:0010605 260 0.023
regulation of rna metabolic process GO:0051252 391 0.023
organonitrogen compound catabolic process GO:1901565 179 0.022
regulation of hydrolase activity GO:0051336 143 0.022
organophosphate metabolic process GO:0019637 370 0.022
regulation of cell growth involved in cardiac muscle cell development GO:0061050 6 0.022
Rat
cellular amino acid metabolic process GO:0006520 107 0.022
nucleoside phosphate metabolic process GO:0006753 283 0.021
negative regulation of molecular function GO:0044092 133 0.021
Rat
apoptotic process GO:0006915 381 0.021
Rat
regulation of cardiac muscle tissue growth GO:0055021 12 0.021
Rat
neuronal action potential GO:0019228 35 0.021
cellular macromolecule localization GO:0070727 122 0.021
Rat
homeostatic process GO:0042592 331 0.021
Rat
single organism catabolic process GO:0044712 283 0.021
negative regulation of striated muscle tissue development GO:0045843 7 0.021
Rat
positive regulation of catalytic activity GO:0043085 184 0.021
regulation of nervous system development GO:0051960 264 0.021
Rat
rna biosynthetic process GO:0032774 380 0.020
regulation of intracellular signal transduction GO:1902531 218 0.020
Rat
carbohydrate derivative metabolic process GO:1901135 346 0.020
receptor mediated endocytosis GO:0006898 42 0.020
Rat
ribose phosphate metabolic process GO:0019693 235 0.019
regulation of transcription dna templated GO:0006355 374 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.019
negative regulation of cardiac muscle hypertrophy GO:0010614 2 0.019
Rat
negative regulation of developmental growth GO:0048640 15 0.019
Rat
purine ribonucleotide metabolic process GO:0009150 227 0.019
cellular component assembly GO:0022607 360 0.019
Rat
nucleobase containing small molecule metabolic process GO:0055086 316 0.019
regulation of protein polymerization GO:0032271 19 0.019
Rat
regulation of protein complex assembly GO:0043254 33 0.018
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.018
regulation of endocytosis GO:0030100 42 0.018
Rat
regulation of nucleic acid templated transcription GO:1903506 380 0.018
nucleotide biosynthetic process GO:0009165 98 0.018
cellular response to abiotic stimulus GO:0071214 85 0.018
Rat
regulation of anatomical structure size GO:0090066 135 0.018
Rat
regulation of metal ion transport GO:0010959 118 0.017
Rat
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
negative regulation of gene expression GO:0010629 199 0.017
regulation of cation channel activity GO:2001257 23 0.017
Rat
organophosphate biosynthetic process GO:0090407 143 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.016
neuron projection development GO:0031175 273 0.016
regulation of neuron projection development GO:0010975 161 0.016
positive regulation of multicellular organismal process GO:0051240 387 0.016
Rat
regulation of ion transmembrane transport GO:0034765 121 0.016
Rat
carbohydrate derivative catabolic process GO:1901136 147 0.016
immune system process GO:0002376 204 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
cellular protein complex assembly GO:0043623 44 0.015
Rat
negative regulation of response to stimulus GO:0048585 155 0.015
Rat
endocytosis GO:0006897 84 0.015
Rat
neuron differentiation GO:0030182 368 0.015
Rat
regulation of microtubule based process GO:0032886 14 0.015
Rat
cell projection organization GO:0030030 302 0.015
single organism organelle organization GO:1902589 180 0.015
Rat
regulation of phosphate metabolic process GO:0019220 349 0.015
Rat
organic substance catabolic process GO:1901575 316 0.015
sensory perception of pain GO:0019233 73 0.015
cardiac muscle hypertrophy GO:0003300 23 0.015
Rat
positive regulation of cellular catabolic process GO:0031331 71 0.015
multicellular organism reproduction GO:0032504 233 0.014
ras protein signal transduction GO:0007265 29 0.014
cell migration GO:0016477 197 0.014
nucleic acid templated transcription GO:0097659 379 0.014
purine containing compound metabolic process GO:0072521 253 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.014
protein polymerization GO:0051258 22 0.014
Rat
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.014
regulation of rna biosynthetic process GO:2001141 381 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
negative regulation of cell death GO:0060548 229 0.014
Rat
sexual reproduction GO:0019953 148 0.014
nucleotide metabolic process GO:0009117 279 0.014
cellular chemical homeostasis GO:0055082 247 0.014
Rat
macromolecular complex assembly GO:0065003 273 0.014
Rat
regulation of body fluid levels GO:0050878 90 0.014
negative regulation of biosynthetic process GO:0009890 168 0.014
regulation of cellular component movement GO:0051270 150 0.013
Rat
regulation of striated muscle tissue development GO:0016202 25 0.013
Rat
head development GO:0060322 247 0.013
organelle organization GO:0006996 266 0.013
Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
cellular catabolic process GO:0044248 295 0.013
multi organism reproductive process GO:0044703 262 0.013
positive regulation of gtpase activity GO:0043547 47 0.013
regulation of purine nucleotide catabolic process GO:0033121 65 0.013
muscle structure development GO:0061061 87 0.013
Rat
anion transport GO:0006820 178 0.013
response to nutrient levels GO:0031667 370 0.013
Rat
cellular response to biotic stimulus GO:0071216 59 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
positive regulation of developmental process GO:0051094 283 0.012
programmed cell death GO:0012501 392 0.012
Rat
regulation of vasoconstriction GO:0019229 44 0.012
Rat
response to other organism GO:0051707 220 0.012
multicellular organismal reproductive process GO:0048609 233 0.012
protein phosphorylation GO:0006468 345 0.012
cation transport GO:0006812 382 0.012
Rat
catabolic process GO:0009056 351 0.012
response to external biotic stimulus GO:0043207 221 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
positive regulation of hydrolase activity GO:0051345 86 0.012
cell adhesion GO:0007155 110 0.012
muscle organ development GO:0007517 50 0.012
Rat
positive regulation of phosphorylation GO:0042327 177 0.012
negative regulation of cell growth GO:0030308 33 0.012
Rat
cellular macromolecular complex assembly GO:0034622 58 0.012
Rat
multicellular organismal signaling GO:0035637 44 0.012
single organism biosynthetic process GO:0044711 342 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
organophosphate catabolic process GO:0046434 148 0.011
regulation of cell projection organization GO:0031344 175 0.011
cellular response to molecule of bacterial origin GO:0071219 56 0.011
positive regulation of cell death GO:0010942 184 0.011
eye morphogenesis GO:0048592 4 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
rna metabolic process GO:0016070 406 0.011
single organism reproductive process GO:0044702 297 0.011
signal release GO:0023061 145 0.011
regulation of response to external stimulus GO:0032101 106 0.011
regulation of catabolic process GO:0009894 113 0.011
negative regulation of phosphate metabolic process GO:0045936 80 0.011
Rat
cell aging GO:0007569 14 0.011
Rat
positive regulation of cell communication GO:0010647 271 0.011
Rat
cell growth GO:0016049 104 0.011
Rat
cellular nitrogen compound catabolic process GO:0044270 163 0.011
purine ribonucleoside catabolic process GO:0046130 124 0.011
regulation of cellular protein metabolic process GO:0032268 267 0.011
regulation of nucleotide catabolic process GO:0030811 65 0.011
negative regulation of transcription dna templated GO:0045892 116 0.011
defense response GO:0006952 194 0.011
muscle tissue development GO:0060537 58 0.011
Rat
cardiocyte differentiation GO:0035051 22 0.011
Rat
physiological cardiac muscle hypertrophy GO:0003301 13 0.011
Rat
macromolecular complex subunit organization GO:0043933 339 0.011
Rat
axis specification GO:0009798 4 0.011
regulation of secretion GO:0051046 224 0.010
transmembrane transport GO:0055085 412 0.010
Rat
positive regulation of neuron differentiation GO:0045666 126 0.010
regulation of catalytic activity GO:0050790 304 0.010
anatomical structure morphogenesis GO:0009653 298 0.010
organic acid transport GO:0015849 116 0.010
positive regulation of mapk cascade GO:0043410 92 0.010
positive regulation of cell development GO:0010720 176 0.010
peptidyl amino acid modification GO:0018193 126 0.010
regulation of actin filament based process GO:0032970 42 0.010
Rat
aromatic compound catabolic process GO:0019439 168 0.010
response to transition metal nanoparticle GO:1990267 122 0.010
response to oxygen levels GO:0070482 265 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.010

Cav2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.040
nervous system disease DOID:863 0 0.040
disease of metabolism DOID:0014667 0 0.025
sensory system disease DOID:0050155 0 0.024
eye and adnexa disease DOID:1492 0 0.024
eye disease DOID:5614 0 0.024
retinal disease DOID:5679 0 0.014
retinal degeneration DOID:8466 0 0.013
central nervous system disease DOID:331 0 0.011