|
binding of sperm to zona pellucida
|
GO:0007339 |
1 |
0.862
|
Mouse |
|
cell cell recognition
|
GO:0009988 |
1 |
0.592
|
Mouse |
|
sperm egg recognition
|
GO:0035036 |
1 |
0.454
|
Mouse |
|
single fertilization
|
GO:0007338 |
3 |
0.404
|
Mouse |
|
protein folding
|
GO:0006457 |
12 |
0.397
|
Yeast |
|
mitotic spindle organization
|
GO:0007052 |
2 |
0.371
|
Fly |
|
cell recognition
|
GO:0008037 |
11 |
0.352
|
Mouse |
|
cellular amino acid metabolic process
|
GO:0006520 |
107 |
0.276
|
|
|
cellular component assembly
|
GO:0022607 |
360 |
0.245
|
Fly |
|
multi organism reproductive process
|
GO:0044703 |
262 |
0.240
|
Mouse |
|
negative regulation of apoptotic process
|
GO:0043066 |
181 |
0.189
|
|
|
toxin transport
|
GO:1901998 |
3 |
0.187
|
Mouse |
|
sexual reproduction
|
GO:0019953 |
148 |
0.180
|
Mouse |
|
protein complex assembly
|
GO:0006461 |
263 |
0.155
|
Fly |
|
cellular component biogenesis
|
GO:0044085 |
368 |
0.152
|
Fly |
|
macromolecular complex subunit organization
|
GO:0043933 |
339 |
0.149
|
Fly |
|
regulation of apoptotic process
|
GO:0042981 |
335 |
0.143
|
|
|
fertilization
|
GO:0009566 |
3 |
0.125
|
Mouse |
|
protein complex biogenesis
|
GO:0070271 |
263 |
0.120
|
Fly |
|
protein complex subunit organization
|
GO:0071822 |
302 |
0.117
|
Fly |
|
single organism reproductive process
|
GO:0044702 |
297 |
0.115
|
Mouse |
|
macromolecular complex assembly
|
GO:0065003 |
273 |
0.113
|
Fly |
|
negative regulation of programmed cell death
|
GO:0043069 |
183 |
0.096
|
|
|
cytoskeleton organization
|
GO:0007010 |
111 |
0.085
|
Fly |
|
programmed cell death
|
GO:0012501 |
392 |
0.082
|
|
|
regulation of transcription dna templated
|
GO:0006355 |
374 |
0.076
|
|
|
regulation of molecular function
|
GO:0065009 |
398 |
0.072
|
|
|
microtubule based process
|
GO:0007017 |
36 |
0.070
|
Fly |
|
copper ion transport
|
GO:0006825 |
6 |
0.069
|
|
|
spindle organization
|
GO:0007051 |
2 |
0.067
|
Fly |
|
organelle organization
|
GO:0006996 |
266 |
0.067
|
Fly |
|
single organism organelle organization
|
GO:1902589 |
180 |
0.066
|
Fly |
|
cellular catabolic process
|
GO:0044248 |
295 |
0.066
|
|
|
catabolic process
|
GO:0009056 |
351 |
0.065
|
|
|
regulation of rna metabolic process
|
GO:0051252 |
391 |
0.064
|
|
|
apoptotic process
|
GO:0006915 |
381 |
0.060
|
|
|
organic substance catabolic process
|
GO:1901575 |
316 |
0.059
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
281 |
0.059
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
334 |
0.051
|
|
|
multicellular organism reproduction
|
GO:0032504 |
233 |
0.051
|
|
|
protein targeting to membrane
|
GO:0006612 |
11 |
0.050
|
|
|
regulation of cellular component organization
|
GO:0051128 |
368 |
0.049
|
|
|
mitotic cell cycle process
|
GO:1903047 |
35 |
0.048
|
Fly |
|
macromolecule catabolic process
|
GO:0009057 |
58 |
0.045
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
2 |
0.045
|
|
|
reproductive process
|
GO:0022414 |
372 |
0.044
|
Mouse |
|
rna metabolic process
|
GO:0016070 |
406 |
0.043
|
|
|
reproduction
|
GO:0000003 |
245 |
0.043
|
Mouse |
|
regulation of programmed cell death
|
GO:0043067 |
341 |
0.042
|
|
|
mitotic cell cycle
|
GO:0000278 |
49 |
0.042
|
Fly |
|
centrosome organization
|
GO:0051297 |
1 |
0.039
|
|
|
negative regulation of cellular macromolecule biosynthetic process
|
GO:2000113 |
141 |
0.039
|
|
|
regulation of retinal cell programmed cell death
|
GO:0046668 |
1 |
0.037
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
289 |
0.034
|
|
|
negative regulation of metabolic process
|
GO:0009892 |
331 |
0.034
|
|
|
proteolysis
|
GO:0006508 |
175 |
0.033
|
|
|
sensory organ development
|
GO:0007423 |
74 |
0.033
|
|
|
response to oxygen levels
|
GO:0070482 |
265 |
0.033
|
|
|
regulation of neuron death
|
GO:1901214 |
115 |
0.032
|
|
|
negative regulation of cell death
|
GO:0060548 |
229 |
0.032
|
|
|
microtubule organizing center organization
|
GO:0031023 |
1 |
0.031
|
|
|
regulation of cell development
|
GO:0060284 |
263 |
0.031
|
|
|
regulation of catalytic activity
|
GO:0050790 |
304 |
0.030
|
|
|
transcription dna templated
|
GO:0006351 |
377 |
0.030
|
|
|
protein transport
|
GO:0015031 |
132 |
0.028
|
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
161 |
0.028
|
|
|
positive regulation of gene expression
|
GO:0010628 |
244 |
0.028
|
|
|
rna biosynthetic process
|
GO:0032774 |
380 |
0.028
|
|
|
oxoacid metabolic process
|
GO:0043436 |
290 |
0.027
|
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
380 |
0.027
|
|
|
organic acid metabolic process
|
GO:0006082 |
292 |
0.026
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
19 |
0.026
|
|
|
regulation of response to stress
|
GO:0080134 |
126 |
0.026
|
|
|
regulation of protein localization
|
GO:0032880 |
81 |
0.026
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
319 |
0.026
|
|
|
regulation of cell proliferation
|
GO:0042127 |
359 |
0.025
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
8 |
0.025
|
|
|
cell cycle process
|
GO:0022402 |
57 |
0.025
|
Fly |
|
gamete generation
|
GO:0007276 |
124 |
0.025
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
376 |
0.024
|
|
|
organelle assembly
|
GO:0070925 |
22 |
0.024
|
Fly |
|
transcription initiation from rna polymerase ii promoter
|
GO:0006367 |
3 |
0.024
|
|
|
ncrna processing
|
GO:0034470 |
3 |
0.024
|
|
|
cation transmembrane transport
|
GO:0098655 |
263 |
0.023
|
|
|
neurological system process
|
GO:0050877 |
219 |
0.023
|
|
|
regulation of insulin secretion involved in cellular response to glucose stimulus
|
GO:0061178 |
14 |
0.023
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
381 |
0.023
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
233 |
0.023
|
|
|
cellular amine metabolic process
|
GO:0044106 |
38 |
0.023
|
|
|
negative regulation of macromolecule biosynthetic process
|
GO:0010558 |
148 |
0.023
|
|
|
centrosome cycle
|
GO:0007098 |
1 |
0.022
|
|
|
immune system process
|
GO:0002376 |
204 |
0.022
|
|
|
amine metabolic process
|
GO:0009308 |
38 |
0.022
|
|
|
homeostatic process
|
GO:0042592 |
331 |
0.022
|
|
|
organelle fission
|
GO:0048285 |
25 |
0.022
|
Fly |
|
organophosphate metabolic process
|
GO:0019637 |
370 |
0.021
|
|
|
cellular response to peptide
|
GO:1901653 |
133 |
0.021
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
25 |
0.021
|
Fly |
|
cell type specific apoptotic process
|
GO:0097285 |
134 |
0.020
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
249 |
0.020
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
349 |
0.020
|
|
|
positive regulation of phosphate metabolic process
|
GO:0045937 |
262 |
0.020
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
316 |
0.019
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
289 |
0.019
|
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
123 |
0.019
|
|
|
locomotion
|
GO:0040011 |
237 |
0.019
|
|
|
positive regulation of cell death
|
GO:0010942 |
184 |
0.018
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
58 |
0.018
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
58 |
0.018
|
|
|
nucleotide metabolic process
|
GO:0009117 |
279 |
0.017
|
|
|
cardiac muscle cell apoptotic process
|
GO:0010659 |
13 |
0.017
|
|
|
aging
|
GO:0007568 |
241 |
0.017
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
159 |
0.017
|
|
|
negative regulation of cell communication
|
GO:0010648 |
158 |
0.017
|
|
|
response to radiation
|
GO:0009314 |
137 |
0.017
|
|
|
regulation of protein phosphorylation
|
GO:0001932 |
183 |
0.017
|
|
|
regulation of immune system process
|
GO:0002682 |
123 |
0.017
|
|
|
nucleic acid templated transcription
|
GO:0097659 |
379 |
0.017
|
|
|
regulation of transferase activity
|
GO:0051338 |
123 |
0.017
|
|
|
regulation of cell differentiation
|
GO:0045595 |
320 |
0.016
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
142 |
0.016
|
|
|
negative regulation of gene expression
|
GO:0010629 |
199 |
0.016
|
|
|
regulation of phosphorylation
|
GO:0042325 |
248 |
0.016
|
|
|
regulation of membrane potential
|
GO:0042391 |
110 |
0.016
|
|
|
blood circulation
|
GO:0008015 |
183 |
0.016
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
29 |
0.016
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
349 |
0.016
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
154 |
0.016
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
247 |
0.016
|
|
|
protein homooligomerization
|
GO:0051260 |
91 |
0.015
|
|
|
spermatid nucleus differentiation
|
GO:0007289 |
1 |
0.015
|
|
|
regulation of signal transduction
|
GO:0009966 |
318 |
0.015
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
229 |
0.015
|
|
|
triglyceride homeostasis
|
GO:0070328 |
2 |
0.015
|
|
|
macromolecule localization
|
GO:0033036 |
252 |
0.015
|
|
|
negative regulation of neuron death
|
GO:1901215 |
69 |
0.015
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
283 |
0.015
|
|
|
cell cycle
|
GO:0007049 |
101 |
0.015
|
Fly |
|
protein tetramerization
|
GO:0051262 |
38 |
0.014
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
260 |
0.014
|
|
|
male gamete generation
|
GO:0048232 |
99 |
0.014
|
|
|
anatomical structure morphogenesis
|
GO:0009653 |
298 |
0.014
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
168 |
0.014
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
106 |
0.014
|
|
|
cellular homeostasis
|
GO:0019725 |
252 |
0.014
|
|
|
organ morphogenesis
|
GO:0009887 |
75 |
0.014
|
|
|
negative regulation of autophagy
|
GO:0010507 |
1 |
0.014
|
|
|
defense response
|
GO:0006952 |
194 |
0.013
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
155 |
0.013
|
|
|
rna catabolic process
|
GO:0006401 |
3 |
0.013
|
|
|
cellular response to stress
|
GO:0033554 |
269 |
0.013
|
|
|
regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060260 |
3 |
0.013
|
|
|
neuron death
|
GO:0070997 |
127 |
0.013
|
|
|
cytoplasmic microtubule organization
|
GO:0031122 |
4 |
0.013
|
|
|
negative regulation of rna biosynthetic process
|
GO:1902679 |
118 |
0.013
|
|
|
positive regulation of molecular function
|
GO:0044093 |
230 |
0.013
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
237 |
0.013
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
252 |
0.013
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
227 |
0.012
|
|
|
de novo protein folding
|
GO:0006458 |
2 |
0.012
|
|
|
regulation of protein modification process
|
GO:0031399 |
194 |
0.012
|
|
|
response to uv c
|
GO:0010225 |
2 |
0.012
|
|
|
negative regulation of glycoprotein metabolic process
|
GO:1903019 |
2 |
0.012
|
|
|
negative regulation of molecular function
|
GO:0044092 |
133 |
0.012
|
|
|
immune effector process
|
GO:0002252 |
53 |
0.012
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
106 |
0.012
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
377 |
0.012
|
|
|
cardiac muscle adaptation
|
GO:0014887 |
1 |
0.012
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
103 |
0.012
|
|
|
cellular response to alcohol
|
GO:0097306 |
87 |
0.012
|
|
|
osteoblast differentiation
|
GO:0001649 |
26 |
0.012
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
119 |
0.011
|
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
197 |
0.011
|
|
|
positive regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060261 |
3 |
0.011
|
|
|
response to inorganic substance
|
GO:0010035 |
377 |
0.011
|
|
|
acylglycerol homeostasis
|
GO:0055090 |
2 |
0.011
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
135 |
0.011
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
253 |
0.011
|
|
|
regulation of neutrophil apoptotic process
|
GO:0033029 |
4 |
0.011
|
|
|
negative regulation of nucleic acid templated transcription
|
GO:1903507 |
117 |
0.011
|
|
|
magnesium ion homeostasis
|
GO:0010960 |
2 |
0.011
|
|
|
regulation of embryonic development
|
GO:0045995 |
2 |
0.011
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
295 |
0.011
|
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
262 |
0.011
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
319 |
0.011
|
|
|
negative regulation of glucose transport
|
GO:0010829 |
4 |
0.011
|
|
|
cardiovascular system development
|
GO:0072358 |
134 |
0.011
|
|
|
response to hypoxia
|
GO:0001666 |
231 |
0.011
|
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
203 |
0.010
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
267 |
0.010
|
|
|
histone ubiquitination
|
GO:0016574 |
1 |
0.010
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
175 |
0.010
|
|
|
positive regulation of peptidyl threonine phosphorylation
|
GO:0010800 |
1 |
0.010
|
|
|
protein autoubiquitination
|
GO:0051865 |
2 |
0.010
|
|
|
response to histamine
|
GO:0034776 |
3 |
0.010
|
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
197 |
0.010
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
4 |
0.010
|
|
|
negative regulation of signaling
|
GO:0023057 |
157 |
0.010
|
|