Rattus norvegicus

17 known processes

Cdc25a

cell division cycle 25 homolog A (S. pombe)

Cdc25a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of rna metabolic process GO:0051252 391 0.216
response to nutrient levels GO:0031667 370 0.205
oxoacid metabolic process GO:0043436 290 0.199
organic acid metabolic process GO:0006082 292 0.198
carboxylic acid metabolic process GO:0019752 289 0.190
programmed cell death GO:0012501 392 0.157
macromolecular complex assembly GO:0065003 273 0.153
protein complex assembly GO:0006461 263 0.135
reproductive system development GO:0061458 128 0.129
regulation of apoptotic process GO:0042981 335 0.127
reproductive structure development GO:0048608 128 0.125
developmental process involved in reproduction GO:0003006 159 0.122
motor neuron axon guidance GO:0008045 1 0.119
cell projection morphogenesis GO:0048858 123 0.116
cellular amino acid metabolic process GO:0006520 107 0.116
rna metabolic process GO:0016070 406 0.104
positive regulation of biosynthetic process GO:0009891 319 0.100
positive regulation of programmed cell death GO:0043068 157 0.100
transcription dna templated GO:0006351 377 0.098
anatomical structure morphogenesis GO:0009653 298 0.093
cell part morphogenesis GO:0032990 123 0.092
central nervous system development GO:0007417 311 0.091
nucleic acid templated transcription GO:0097659 379 0.090
positive regulation of nucleic acid templated transcription GO:1903508 197 0.083
response to nutrient GO:0007584 248 0.083
carbohydrate derivative metabolic process GO:1901135 346 0.081
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.079
rna biosynthetic process GO:0032774 380 0.078
regulation of programmed cell death GO:0043067 341 0.078
cell projection organization GO:0030030 302 0.073
cellular component morphogenesis GO:0032989 155 0.073
cell type specific apoptotic process GO:0097285 134 0.073
positive regulation of gene expression GO:0010628 244 0.072
positive regulation of transcription dna templated GO:0045893 197 0.072
heart morphogenesis GO:0003007 3 0.071
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.071
cell morphogenesis involved in differentiation GO:0000904 119 0.069
protein oligomerization GO:0051259 191 0.067
neuron projection development GO:0031175 273 0.064
cellular component assembly GO:0022607 360 0.062
axon development GO:0061564 96 0.061
cell motility GO:0048870 202 0.061
regulation of rna biosynthetic process GO:2001141 381 0.060
cell migration GO:0016477 197 0.060
amine metabolic process GO:0009308 38 0.060
protein complex biogenesis GO:0070271 263 0.058
apoptotic process GO:0006915 381 0.058
anion transport GO:0006820 178 0.057
organic substance catabolic process GO:1901575 316 0.056
protein autophosphorylation GO:0046777 66 0.054
wound healing GO:0042060 122 0.054
regulation of cellular ketone metabolic process GO:0010565 27 0.054
cellular component biogenesis GO:0044085 368 0.054
axonogenesis GO:0007409 71 0.053
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.053
regulation of transcription dna templated GO:0006355 374 0.051
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.051
cellular ketone metabolic process GO:0042180 51 0.051
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.051
regulation of cellular amino acid metabolic process GO:0006521 2 0.049
regulation of cell development GO:0060284 263 0.049
aging GO:0007568 241 0.049
cellular catabolic process GO:0044248 295 0.049
regulation of phagocytosis engulfment GO:0060099 4 0.048
cellular component movement GO:0006928 248 0.045
regulation of nucleic acid templated transcription GO:1903506 380 0.045
cation transmembrane transport GO:0098655 263 0.045
positive regulation of apoptotic process GO:0043065 154 0.044
response to extracellular stimulus GO:0009991 380 0.044
protein phosphorylation GO:0006468 345 0.043
organophosphate metabolic process GO:0019637 370 0.043
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.043
negative regulation of macromolecule metabolic process GO:0010605 260 0.042
cellular amide metabolic process GO:0043603 44 0.042
single organism carbohydrate metabolic process GO:0044723 118 0.042
glial cell differentiation GO:0010001 65 0.041
inorganic cation transmembrane transport GO:0098662 202 0.041
epithelium development GO:0060429 96 0.041
macromolecular complex subunit organization GO:0043933 339 0.041
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.039
regulation of cellular amine metabolic process GO:0033238 8 0.039
negative regulation of ion transmembrane transporter activity GO:0032413 12 0.038
regulation of nervous system development GO:0051960 264 0.038
positive regulation of cellular biosynthetic process GO:0031328 295 0.037
transcription from rna polymerase ii promoter GO:0006366 252 0.037
regulation of protein phosphorylation GO:0001932 183 0.037
cellular modified amino acid metabolic process GO:0006575 61 0.037
fatty acid metabolic process GO:0006631 99 0.036
neuron differentiation GO:0030182 368 0.036
regulation of phosphorus metabolic process GO:0051174 349 0.036
positive regulation of rna metabolic process GO:0051254 203 0.036
response to metal ion GO:0010038 253 0.036
neuron apoptotic process GO:0051402 88 0.036
organ morphogenesis GO:0009887 75 0.036
cellular amine metabolic process GO:0044106 38 0.035
regulation of neuron differentiation GO:0045664 208 0.035
regulation of signal transduction GO:0009966 318 0.035
regulation of phosphate metabolic process GO:0019220 349 0.034
regulation of neurogenesis GO:0050767 247 0.033
multicellular organism reproduction GO:0032504 233 0.033
vesicle mediated transport GO:0016192 181 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.033
peptide biosynthetic process GO:0043043 3 0.033
response to vitamin GO:0033273 131 0.032
negative regulation of neurogenesis GO:0050768 78 0.032
regulation of neuron projection development GO:0010975 161 0.032
positive regulation of cell death GO:0010942 184 0.032
single organism behavior GO:0044708 130 0.031
negative regulation of apoptotic process GO:0043066 181 0.031
cell morphogenesis GO:0000902 142 0.031
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.031
reproductive process GO:0022414 372 0.030
response to electrical stimulus involved in regulation of muscle adaptation GO:0014878 4 0.030
negative regulation of intracellular estrogen receptor signaling pathway GO:0033147 2 0.030
negative regulation of cellular biosynthetic process GO:0031327 161 0.030
locomotion GO:0040011 237 0.030
sensory organ development GO:0007423 74 0.030
positive regulation of neurogenesis GO:0050769 165 0.029
response to growth factor GO:0070848 189 0.029
cellular response to endogenous stimulus GO:0071495 377 0.029
macromolecule localization GO:0033036 252 0.029
endocytosis GO:0006897 84 0.028
positive regulation of epidermis development GO:0045684 1 0.028
enzyme linked receptor protein signaling pathway GO:0007167 116 0.028
inorganic ion transmembrane transport GO:0098660 229 0.028
regulation of catabolic process GO:0009894 113 0.027
carbohydrate metabolic process GO:0005975 130 0.027
regulation of cell morphogenesis GO:0022604 77 0.027
reproduction GO:0000003 245 0.027
catabolic process GO:0009056 351 0.026
regulation of cellular catabolic process GO:0031329 101 0.026
peptide metabolic process GO:0006518 32 0.025
homeostatic process GO:0042592 331 0.025
negative regulation of transcription dna templated GO:0045892 116 0.025
protein complex subunit organization GO:0071822 302 0.025
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.025
positive regulation of nervous system development GO:0051962 178 0.025
taxis GO:0042330 67 0.025
cellular response to oxygen containing compound GO:1901701 386 0.024
cellular response to oxidative stress GO:0034599 76 0.023
regulation of cell differentiation GO:0045595 320 0.023
regulation of neuron apoptotic process GO:0043523 83 0.023
multicellular organismal reproductive process GO:0048609 233 0.023
regulation of cell proliferation GO:0042127 359 0.023
neuron projection morphogenesis GO:0048812 122 0.023
response to decreased oxygen levels GO:0036293 237 0.022
regulation of neuron death GO:1901214 115 0.022
cellular response to stress GO:0033554 269 0.022
positive regulation of cell development GO:0010720 176 0.022
cellular response to hormone stimulus GO:0032870 247 0.022
cellular response to growth factor stimulus GO:0071363 162 0.022
single organism biosynthetic process GO:0044711 342 0.021
positive regulation of phosphate metabolic process GO:0045937 262 0.021
cellular macromolecular complex assembly GO:0034622 58 0.021
skeletal muscle satellite cell proliferation GO:0014841 1 0.021
positive regulation of cell differentiation GO:0045597 217 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
peptidyl serine phosphorylation GO:0018105 33 0.021
negative regulation of molecular function GO:0044092 133 0.021
positive regulation of cell communication GO:0010647 271 0.021
chemotaxis GO:0006935 66 0.021
protein homooligomerization GO:0051260 91 0.020
regulation of phosphorylation GO:0042325 248 0.020
monocarboxylic acid metabolic process GO:0032787 152 0.020
sex differentiation GO:0007548 113 0.020
gonad development GO:0008406 104 0.020
regulation of cellular component movement GO:0051270 150 0.020
negative regulation of rna biosynthetic process GO:1902679 118 0.020
development of primary sexual characteristics GO:0045137 107 0.020
response to acid chemical GO:0001101 222 0.020
regulation of cell projection organization GO:0031344 175 0.020
cell cell signaling GO:0007267 335 0.020
cellular response to acid chemical GO:0071229 75 0.020
regulation of ion transmembrane transport GO:0034765 121 0.020
negative regulation of signal transduction GO:0009968 83 0.020
regulation of protein modification process GO:0031399 194 0.020
calcium ion transmembrane transport GO:0070588 70 0.019
carboxylic acid transport GO:0046942 115 0.019
positive regulation of rna biosynthetic process GO:1902680 197 0.019
s shaped body morphogenesis GO:0072050 2 0.019
peptidyl amino acid modification GO:0018193 126 0.019
organonitrogen compound catabolic process GO:1901565 179 0.019
neuron death GO:0070997 127 0.019
male sex differentiation GO:0046661 64 0.019
regulation of body fluid levels GO:0050878 90 0.019
regulation of cation channel activity GO:2001257 23 0.019
ribose phosphate metabolic process GO:0019693 235 0.018
formation of primary germ layer GO:0001704 1 0.018
hair follicle development GO:0001942 2 0.018
organophosphate biosynthetic process GO:0090407 143 0.018
tube development GO:0035295 89 0.018
autonomic nervous system development GO:0048483 3 0.018
proteolysis GO:0006508 175 0.018
metanephric part of ureteric bud development GO:0035502 1 0.018
localization of cell GO:0051674 202 0.017
neuron development GO:0048666 286 0.017
behavioral response to ethanol GO:0048149 1 0.017
positive regulation of neuron differentiation GO:0045666 126 0.017
regulation of protein kinase activity GO:0045859 105 0.017
gliogenesis GO:0042063 93 0.017
negative regulation of neuron apoptotic process GO:0043524 45 0.017
cellular protein complex assembly GO:0043623 44 0.017
response to inorganic substance GO:0010035 377 0.016
negative regulation of developmental process GO:0051093 125 0.016
positive regulation of protein modification process GO:0031401 142 0.016
cellular response to retinoic acid GO:0071300 27 0.016
cellular response to vitamin e GO:0071306 3 0.016
negative regulation of cell death GO:0060548 229 0.016
negative regulation of neuron differentiation GO:0045665 62 0.016
ion transmembrane transport GO:0034220 365 0.015
positive regulation of cell projection organization GO:0031346 111 0.015
head development GO:0060322 247 0.015
response to carbohydrate GO:0009743 183 0.015
negative regulation of cell development GO:0010721 82 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
regulation of anatomical structure size GO:0090066 135 0.015
molting cycle GO:0042303 3 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
dendrite development GO:0016358 72 0.015
regulation of cellular localization GO:0060341 263 0.015
cellular response to abiotic stimulus GO:0071214 85 0.014
Human
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.014
ras protein signal transduction GO:0007265 29 0.014
negative regulation of metabolic process GO:0009892 331 0.014
negative regulation of rna metabolic process GO:0051253 123 0.014
response to wounding GO:0009611 254 0.014
peptidyl tyrosine modification GO:0018212 72 0.014
mesoderm development GO:0007498 2 0.014
molting cycle process GO:0022404 2 0.014
negative regulation of cell communication GO:0010648 158 0.014
metal ion transport GO:0030001 289 0.014
axis specification GO:0009798 4 0.014
tissue development GO:0009888 252 0.014
intracellular transport GO:0046907 185 0.014
negative regulation of nucleic acid templated transcription GO:1903507 117 0.014
glucose metabolic process GO:0006006 52 0.014
transmembrane transport GO:0055085 412 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
hair cycle process GO:0022405 2 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
cellular lipid metabolic process GO:0044255 208 0.013
urogenital system development GO:0001655 78 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
response to monosaccharide GO:0034284 159 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
cellular modified amino acid biosynthetic process GO:0042398 18 0.013
regulation of dendrite development GO:0050773 59 0.013
organic acid biosynthetic process GO:0016053 83 0.013
regulation of cell cycle GO:0051726 73 0.013
negative regulation of gene expression GO:0010629 199 0.013
cellular macromolecule localization GO:0070727 122 0.013
ribonucleoside catabolic process GO:0042454 126 0.013
circulatory system development GO:0072359 134 0.013
regulation of cellular protein metabolic process GO:0032268 267 0.013
regulation of molecular function GO:0065009 398 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
response to mechanical stimulus GO:0009612 134 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
single organism reproductive process GO:0044702 297 0.012
positive regulation of cellular component biogenesis GO:0044089 55 0.012
negative regulation of neuron death GO:1901215 69 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
neuromuscular synaptic transmission GO:0007274 2 0.012
secretion GO:0046903 307 0.012
response to oxygen levels GO:0070482 265 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
negative regulation of stress activated protein kinase signaling cascade GO:0070303 4 0.012
embryonic pattern specification GO:0009880 1 0.012
nucleoside phosphate biosynthetic process GO:1901293 102 0.012
striated muscle contraction GO:0006941 44 0.012
positive regulation of phosphorus metabolic process GO:0010562 262 0.011
regulation of mapk cascade GO:0043408 116 0.011
multi organism reproductive process GO:0044703 262 0.011
nitrogen compound transport GO:0071705 229 0.011
brain development GO:0007420 247 0.011
skin development GO:0043588 17 0.011
male mating behavior GO:0060179 3 0.011
positive regulation of response to stimulus GO:0048584 285 0.011
regulation of system process GO:0044057 208 0.011
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 3 0.011
cellular response to nitrogen compound GO:1901699 210 0.011
ovarian follicle development GO:0001541 31 0.011
protein localization GO:0008104 191 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
regulation of cell cycle arrest GO:0071156 2 0.011
astrocyte development GO:0014002 4 0.011
single organism intracellular transport GO:1902582 166 0.011
positive regulation of developmental process GO:0051094 283 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
histone h3 k9 modification GO:0061647 2 0.011
immune system process GO:0002376 204 0.011
response to glucose GO:0009749 136 0.011
neurotrophin production GO:0032898 2 0.011
regulation of axonogenesis GO:0050770 37 0.011
organ formation GO:0048645 3 0.011
positive regulation of humoral immune response GO:0002922 2 0.011
regulation of defense response GO:0031347 68 0.011
muscle structure development GO:0061061 87 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.010
embryo development GO:0009790 49 0.010
heterocycle catabolic process GO:0046700 167 0.010
endocardial cushion development GO:0003197 1 0.010
gastrulation GO:0007369 2 0.010
small gtpase mediated signal transduction GO:0007264 36 0.010
tissue morphogenesis GO:0048729 22 0.010
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.010
carbohydrate phosphorylation GO:0046835 16 0.010
cellular response to organic cyclic compound GO:0071407 202 0.010
neuron fate specification GO:0048665 3 0.010
negative regulation of signaling GO:0023057 157 0.010
establishment of neuroblast polarity GO:0045200 1 0.010
nucleotide metabolic process GO:0009117 279 0.010
developmental growth GO:0048589 100 0.010

Cdc25a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.091
urinary system disease DOID:18 0 0.091
long qt syndrome DOID:2843 0 0.030
nervous system disease DOID:863 0 0.030
kidney disease DOID:557 0 0.022
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
thyroid gland disease DOID:50 0 0.013
hypothyroidism DOID:1459 0 0.013
congenital hypothyroidism DOID:0050328 0 0.013
endocrine system disease DOID:28 0 0.013
sensory system disease DOID:0050155 0 0.011