Rattus norvegicus

44 known processes

Cdkn2b

cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)

(Aliases: p15)

Cdkn2b biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of response to stress GO:0080134 126 0.658
response to corticosteroid GO:0031960 235 0.602
response to lipopolysaccharide GO:0032496 191 0.593
response to external biotic stimulus GO:0043207 221 0.564
reproductive process GO:0022414 372 0.536
response to molecule of bacterial origin GO:0002237 194 0.519
positive regulation of response to stimulus GO:0048584 285 0.516
Human
immune system process GO:0002376 204 0.483
Human Mouse
tissue development GO:0009888 252 0.474
regulation of secretion by cell GO:1903530 208 0.461
response to glucocorticoid GO:0051384 223 0.452
regulation of nucleic acid templated transcription GO:1903506 380 0.437
negative regulation of metabolic process GO:0009892 331 0.422
Human
intracellular signal transduction GO:0035556 314 0.408
response to wounding GO:0009611 254 0.401
reproductive system development GO:0061458 128 0.386
coronary vasculature morphogenesis GO:0060977 3 0.381
response to biotic stimulus GO:0009607 226 0.374
positive regulation of cell communication GO:0010647 271 0.366
Human
organonitrogen compound biosynthetic process GO:1901566 167 0.358
response to estrogen GO:0043627 232 0.344
regulation of phosphorus metabolic process GO:0051174 349 0.320
Human
defense response GO:0006952 194 0.313
response to bacterium GO:0009617 200 0.312
response to estradiol GO:0032355 164 0.311
regulation of multicellular organismal development GO:2000026 376 0.308
negative regulation of developmental process GO:0051093 125 0.307
protein phosphorylation GO:0006468 345 0.296
Human
reproductive structure development GO:0048608 128 0.296
single organism reproductive process GO:0044702 297 0.295
positive regulation of signaling GO:0023056 270 0.295
Human
positive regulation of rna metabolic process GO:0051254 203 0.290
transcription dna templated GO:0006351 377 0.283
nucleic acid templated transcription GO:0097659 379 0.281
positive regulation of multicellular organismal process GO:0051240 387 0.280
single organism biosynthetic process GO:0044711 342 0.278
response to cytokine GO:0034097 215 0.276
cellular response to oxygen containing compound GO:1901701 386 0.274
positive regulation of developmental process GO:0051094 283 0.272
negative regulation of biosynthetic process GO:0009890 168 0.270
response to other organism GO:0051707 220 0.269
gland development GO:0048732 155 0.267
regulation of transcription dna templated GO:0006355 374 0.266
regulation of phosphorylation GO:0042325 248 0.262
Human
regulation of signal transduction GO:0009966 318 0.252
Human
positive regulation of cellular biosynthetic process GO:0031328 295 0.252
positive regulation of gene expression GO:0010628 244 0.250
regulation of mapk cascade GO:0043408 116 0.248
regulation of cell proliferation GO:0042127 359 0.234
multicellular organism reproduction GO:0032504 233 0.228
behavior GO:0007610 205 0.227
regulation of rna metabolic process GO:0051252 391 0.225
positive regulation of signal transduction GO:0009967 175 0.220
Human
regeneration GO:0031099 163 0.219
organ regeneration GO:0031100 101 0.213
positive regulation of phosphorus metabolic process GO:0010562 262 0.212
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.212
positive regulation of rna biosynthetic process GO:1902680 197 0.202
regulation of cell differentiation GO:0045595 320 0.202
regulation of protein kinase activity GO:0045859 105 0.200
Human
regulation of phosphate metabolic process GO:0019220 349 0.199
Human
rna biosynthetic process GO:0032774 380 0.197
purine ribonucleotide biosynthetic process GO:0009152 81 0.197
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.189
secretion by cell GO:0032940 248 0.189
head development GO:0060322 247 0.187
mapk cascade GO:0000165 140 0.184
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.182
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.181
developmental process involved in reproduction GO:0003006 159 0.178
regulation of rna biosynthetic process GO:2001141 381 0.176
homeostatic process GO:0042592 331 0.172
multi multicellular organism process GO:0044706 138 0.171
negative regulation of rna metabolic process GO:0051253 123 0.170
cellular response to endogenous stimulus GO:0071495 377 0.163
Human
negative regulation of nucleic acid templated transcription GO:1903507 117 0.162
positive regulation of cellular protein metabolic process GO:0032270 167 0.161
macromolecule localization GO:0033036 252 0.160
regulation of cell development GO:0060284 263 0.160
multicellular organismal reproductive process GO:0048609 233 0.160
development of primary sexual characteristics GO:0045137 107 0.156
regulation of protein metabolic process GO:0051246 289 0.154
Human
organophosphate biosynthetic process GO:0090407 143 0.153
positive regulation of cell motility GO:2000147 97 0.153
small molecule biosynthetic process GO:0044283 124 0.152
positive regulation of protein metabolic process GO:0051247 178 0.148
regulation of molecular function GO:0065009 398 0.147
Human
central nervous system development GO:0007417 311 0.147
cation homeostasis GO:0055080 195 0.146
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.141
rna metabolic process GO:0016070 406 0.139
cellular response to hormone stimulus GO:0032870 247 0.139
negative regulation of response to stimulus GO:0048585 155 0.139
sex differentiation GO:0007548 113 0.139
immune system development GO:0002520 41 0.138
Human Mouse
negative regulation of transport GO:0051051 136 0.137
negative regulation of cellular biosynthetic process GO:0031327 161 0.136
cellular response to stress GO:0033554 269 0.136
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.134
female gonad development GO:0008585 53 0.134
purine ribonucleotide metabolic process GO:0009150 227 0.129
regulation of secretion GO:0051046 224 0.128
organophosphate metabolic process GO:0019637 370 0.127
purine nucleotide biosynthetic process GO:0006164 83 0.125
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.124
inflammatory response GO:0006954 150 0.124
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.124
regulation of cellular protein metabolic process GO:0032268 267 0.123
Human
cell motility GO:0048870 202 0.123
forebrain development GO:0030900 98 0.120
ion homeostasis GO:0050801 212 0.118
response to oxygen levels GO:0070482 265 0.118
secretion GO:0046903 307 0.116
negative regulation of multicellular organismal process GO:0051241 203 0.115
vascular process in circulatory system GO:0003018 96 0.115
negative regulation of cell differentiation GO:0045596 99 0.114
sexual reproduction GO:0019953 148 0.112
positive regulation of phosphate metabolic process GO:0045937 262 0.112
wound healing GO:0042060 122 0.112
positive regulation of intracellular signal transduction GO:1902533 138 0.112
ribonucleotide biosynthetic process GO:0009260 85 0.111
signal transduction by phosphorylation GO:0023014 144 0.110
g protein coupled receptor signaling pathway GO:0007186 242 0.109
signal release GO:0023061 145 0.107
response to temperature stimulus GO:0009266 94 0.107
apoptotic process GO:0006915 381 0.104
muscle contraction GO:0006936 88 0.103
regulation of protein modification process GO:0031399 194 0.103
Human
neurological system process GO:0050877 219 0.102
regulation of intracellular signal transduction GO:1902531 218 0.101
programmed cell death GO:0012501 392 0.100
positive regulation of cell proliferation GO:0008284 249 0.100
phasic smooth muscle contraction GO:0014821 3 0.100
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.100
cellular response to cytokine stimulus GO:0071345 127 0.100
transcription from rna polymerase ii promoter GO:0006366 252 0.099
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.099
ribonucleotide metabolic process GO:0009259 231 0.098
telencephalon development GO:0021537 62 0.098
locomotion GO:0040011 237 0.098
regulation of protein phosphorylation GO:0001932 183 0.097
Human
regulation of cellular localization GO:0060341 263 0.096
muscle system process GO:0003012 115 0.096
neuron development GO:0048666 286 0.095
response to nutrient GO:0007584 248 0.094
Human
reproduction GO:0000003 245 0.093
positive regulation of secretion GO:0051047 140 0.093
regulation of cellular component organization GO:0051128 368 0.092
negative regulation of macromolecule metabolic process GO:0010605 260 0.090
Human
regulation of hormone levels GO:0010817 187 0.090
cell migration GO:0016477 197 0.089
regulation of nucleotide biosynthetic process GO:0030808 47 0.088
regulation of defense response GO:0031347 68 0.087
cellular component movement GO:0006928 248 0.087
regulation of camp metabolic process GO:0030814 43 0.087
erk1 and erk2 cascade GO:0070371 48 0.086
regulation of organ formation GO:0003156 2 0.085
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.085
positive regulation of biosynthetic process GO:0009891 319 0.085
multi organism reproductive process GO:0044703 262 0.085
sensory perception GO:0007600 101 0.084
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.084
cellular lipid metabolic process GO:0044255 208 0.084
negative regulation of programmed cell death GO:0043069 183 0.082
positive regulation of cell differentiation GO:0045597 217 0.082
negative regulation of gene expression GO:0010629 199 0.081
cell projection organization GO:0030030 302 0.081
gliogenesis GO:0042063 93 0.081
hematopoietic or lymphoid organ development GO:0048534 36 0.081
Human Mouse
positive regulation of phosphorylation GO:0042327 177 0.080
cytokine mediated signaling pathway GO:0019221 43 0.080
ribose phosphate metabolic process GO:0019693 235 0.077
response to toxic substance GO:0009636 133 0.077
negative regulation of cellular metabolic process GO:0031324 281 0.077
Human
oxoacid metabolic process GO:0043436 290 0.077
response to extracellular stimulus GO:0009991 380 0.077
Human
positive regulation of transcription dna templated GO:0045893 197 0.077
cellular response to glucocorticoid stimulus GO:0071385 68 0.076
response to oxidative stress GO:0006979 186 0.075
lipid metabolic process GO:0006629 283 0.074
purine containing compound biosynthetic process GO:0072522 85 0.074
renal system development GO:0072001 67 0.074
alcohol metabolic process GO:0006066 77 0.073
carboxylic acid metabolic process GO:0019752 289 0.073
regulation of apoptotic process GO:0042981 335 0.072
cellular component assembly GO:0022607 360 0.072
enzyme linked receptor protein signaling pathway GO:0007167 116 0.072
Human
positive regulation of secretion by cell GO:1903532 128 0.071
regulation of neurogenesis GO:0050767 247 0.071
cellular response to steroid hormone stimulus GO:0071383 93 0.070
cyclic nucleotide metabolic process GO:0009187 80 0.070
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.070
anatomical structure morphogenesis GO:0009653 298 0.070
kidney morphogenesis GO:0060993 13 0.070
positive regulation of nucleic acid templated transcription GO:1903508 197 0.069
heart development GO:0007507 72 0.068
positive regulation of kinase activity GO:0033674 77 0.068
regulation of nervous system development GO:0051960 264 0.067
regulation of ion transport GO:0043269 245 0.067
neuron differentiation GO:0030182 368 0.067
response to peptide hormone GO:0043434 278 0.067
response to mechanical stimulus GO:0009612 134 0.066
positive regulation of transport GO:0051050 245 0.066
cell cell signaling GO:0007267 335 0.066
aging GO:0007568 241 0.066
positive regulation of cell death GO:0010942 184 0.066
negative regulation of neuron differentiation GO:0045665 62 0.065
response to growth factor GO:0070848 189 0.065
Human
regulation of cell motility GO:2000145 131 0.064
response to food GO:0032094 27 0.064
cyclic purine nucleotide metabolic process GO:0052652 62 0.064
myeloid cell differentiation GO:0030099 22 0.064
Human
negative regulation of rna biosynthetic process GO:1902679 118 0.063
regulation of muscle system process GO:0090257 79 0.063
chemical homeostasis GO:0048878 292 0.062
regulation of immune system process GO:0002682 123 0.062
cellular metal ion homeostasis GO:0006875 172 0.062
female pregnancy GO:0007565 122 0.062
regulation of purine nucleotide metabolic process GO:1900542 115 0.061
localization of cell GO:0051674 202 0.061
regulation of catalytic activity GO:0050790 304 0.061
Human
positive regulation of mapk cascade GO:0043410 92 0.060
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 19 0.060
cellular response to corticosteroid stimulus GO:0071384 69 0.059
response to inorganic substance GO:0010035 377 0.059
negative regulation of cell development GO:0010721 82 0.058
camp metabolic process GO:0046058 63 0.058
single organism intracellular transport GO:1902582 166 0.058
liver development GO:0001889 90 0.058
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.058
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.057
glycerolipid metabolic process GO:0046486 67 0.057
positive regulation of protein modification process GO:0031401 142 0.057
leukocyte differentiation GO:0002521 30 0.057
response to nutrient levels GO:0031667 370 0.057
Human
regulation of cell migration GO:0030334 128 0.056
cyclic nucleotide biosynthetic process GO:0009190 63 0.056
regulation of blood vessel size GO:0050880 89 0.055
negative regulation of transcription dna templated GO:0045892 116 0.055
nucleoside phosphate biosynthetic process GO:1901293 102 0.055
developmental induction GO:0031128 2 0.055
gonad development GO:0008406 104 0.054
positive regulation of programmed cell death GO:0043068 157 0.054
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.054
response to carbohydrate GO:0009743 183 0.054
positive regulation of molecular function GO:0044093 230 0.053
single organism membrane organization GO:0044802 74 0.053
regulation of epithelial cell differentiation GO:0030856 12 0.053
cardiovascular system development GO:0072358 134 0.053
regulation of cellular amino acid metabolic process GO:0006521 2 0.052
cellular response to growth factor stimulus GO:0071363 162 0.052
Human
cellular response to lipid GO:0071396 201 0.052
neuron projection morphogenesis GO:0048812 122 0.052
regulation of stem cell proliferation GO:0072091 14 0.052
nucleotide metabolic process GO:0009117 279 0.051
cation transport GO:0006812 382 0.051
cellular ion homeostasis GO:0006873 184 0.051
regulation of system process GO:0044057 208 0.051
hemopoiesis GO:0030097 34 0.049
Human
positive regulation of protein phosphorylation GO:0001934 135 0.049
purine containing compound metabolic process GO:0072521 253 0.049
epithelium development GO:0060429 96 0.048
cellular response to insulin stimulus GO:0032869 81 0.048
positive regulation of immune system process GO:0002684 90 0.048
cellular protein localization GO:0034613 122 0.047
regulation of transferase activity GO:0051338 123 0.047
Human
sensory perception of pain GO:0019233 73 0.047
regulation of locomotion GO:0040012 148 0.047
digestive system development GO:0055123 41 0.046
leukocyte homeostasis GO:0001776 7 0.046
positive regulation of apoptotic process GO:0043065 154 0.046
response to hypoxia GO:0001666 231 0.046
negative regulation of immune system process GO:0002683 39 0.046
protein processing GO:0016485 68 0.046
nucleotide biosynthetic process GO:0009165 98 0.046
striated muscle contraction GO:0006941 44 0.045
organic acid metabolic process GO:0006082 292 0.045
blood vessel morphogenesis GO:0048514 58 0.045
positive regulation of tolerance induction dependent upon immune response GO:0002654 1 0.045
carbohydrate derivative metabolic process GO:1901135 346 0.045
cellular ketone metabolic process GO:0042180 51 0.044
regulation of camp biosynthetic process GO:0030817 38 0.044
regulation of systemic arterial blood pressure by norepinephrine epinephrine GO:0001993 2 0.044
negative regulation of apoptotic process GO:0043066 181 0.044
skeletal system development GO:0001501 41 0.044
response to peptide GO:1901652 292 0.044
cell type specific apoptotic process GO:0097285 134 0.044
striated muscle tissue development GO:0014706 58 0.044
negative regulation of neurogenesis GO:0050768 78 0.043
transmembrane transport GO:0055085 412 0.043
regulation of neuron differentiation GO:0045664 208 0.043
regulation of cell cycle GO:0051726 73 0.042
Human Mouse
regulation of cellular ketone metabolic process GO:0010565 27 0.042
cell activation GO:0001775 97 0.042
intracellular transport GO:0046907 185 0.042
positive regulation of vasodilation GO:0045909 29 0.042
positive regulation of brown fat cell proliferation GO:0070349 1 0.042
regulation of hormone secretion GO:0046883 106 0.042
negative regulation of secretion GO:0051048 82 0.041
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.041
Human
cellular homeostasis GO:0019725 252 0.041
organelle organization GO:0006996 266 0.041
organ induction GO:0001759 1 0.041
muscle tissue development GO:0060537 58 0.041
cellular amine metabolic process GO:0044106 38 0.041
vasculature development GO:0001944 70 0.040
negative regulation of molecular function GO:0044092 133 0.040
Human
positive regulation of cardiac muscle tissue growth GO:0055023 9 0.040
cellular catabolic process GO:0044248 295 0.039
angiogenesis involved in coronary vascular morphogenesis GO:0060978 3 0.039
regulation of nucleotide metabolic process GO:0006140 117 0.039
regulation of tolerance induction dependent upon immune response GO:0002652 1 0.039
regulation of monooxygenase activity GO:0032768 8 0.039
carbohydrate derivative biosynthetic process GO:1901137 124 0.038
organ formation GO:0048645 3 0.038
regulation of programmed cell death GO:0043067 341 0.038
bmp signaling pathway GO:0030509 4 0.038
response to reactive oxygen species GO:0000302 120 0.038
ribose phosphate biosynthetic process GO:0046390 87 0.038
regulation of catabolic process GO:0009894 113 0.037
development of primary female sexual characteristics GO:0046545 56 0.037
tube development GO:0035295 89 0.037
regulation of erk1 and erk2 cascade GO:0070372 41 0.037
neuron apoptotic process GO:0051402 88 0.037
hormone transport GO:0009914 121 0.037
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.037
nucleoside phosphate metabolic process GO:0006753 283 0.036
positive regulation of cellular component movement GO:0051272 102 0.036
response to testosterone GO:0033574 55 0.036
epithelial cell differentiation GO:0030855 71 0.036
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.036
regulation of metal ion transport GO:0010959 118 0.035
mesonephros development GO:0001823 14 0.035
cell growth GO:0016049 104 0.035
single organism behavior GO:0044708 130 0.035
hepaticobiliary system development GO:0061008 90 0.035
ovulation cycle process GO:0022602 50 0.035
specification of organ identity GO:0010092 2 0.035
amine metabolic process GO:0009308 38 0.034
regulation of kinase activity GO:0043549 117 0.034
Human
somatostatin receptor signaling pathway GO:0038169 4 0.034
memory GO:0007613 54 0.034
steroid metabolic process GO:0008202 73 0.034
dephosphorylation GO:0016311 98 0.034
brain development GO:0007420 247 0.034
leukocyte activation GO:0045321 76 0.034
positive regulation of tolerance induction to nonself antigen GO:0002657 1 0.034
regulation of anatomical structure size GO:0090066 135 0.034
cellular cation homeostasis GO:0030003 180 0.034
lipid biosynthetic process GO:0008610 128 0.034
male sex differentiation GO:0046661 64 0.033
membrane organization GO:0061024 94 0.033
angiogenesis GO:0001525 53 0.033
organ growth GO:0035265 24 0.033
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.033
positive regulation of cellular component organization GO:0051130 200 0.033
multicellular organismal homeostasis GO:0048871 49 0.033
purine nucleotide metabolic process GO:0006163 229 0.032
fatty acid metabolic process GO:0006631 99 0.032
kidney epithelium development GO:0072073 19 0.032
ureteric bud development GO:0001657 14 0.032
positive regulation of cell development GO:0010720 176 0.032
organic substance catabolic process GO:1901575 316 0.032
hair follicle development GO:0001942 2 0.032
learning or memory GO:0007611 90 0.032
cell morphogenesis GO:0000902 142 0.032
t cell tolerance induction GO:0002517 3 0.031
response to decreased oxygen levels GO:0036293 237 0.031
catabolic process GO:0009056 351 0.031
response to insulin GO:0032868 133 0.031
small gtpase mediated signal transduction GO:0007264 36 0.031
muscle structure development GO:0061061 87 0.031
vasodilation GO:0042311 44 0.031
neuron projection development GO:0031175 273 0.031
negative regulation of cell proliferation GO:0008285 119 0.031
negative regulation of nervous system development GO:0051961 79 0.030
blood vessel development GO:0001568 69 0.030
regulation of cellular component movement GO:0051270 150 0.030
regulation of bmp signaling pathway GO:0030510 2 0.030
phosphatidylcholine biosynthetic process GO:0006656 5 0.030
regulation of response to external stimulus GO:0032101 106 0.030
female sex differentiation GO:0046660 59 0.030
oxidation reduction process GO:0055114 304 0.030
protein localization GO:0008104 191 0.029
positive regulation of epithelial cell proliferation GO:0050679 32 0.029
positive regulation of transferase activity GO:0051347 81 0.029
jak stat cascade GO:0007259 26 0.029
urogenital system development GO:0001655 78 0.029
organic hydroxy compound metabolic process GO:1901615 115 0.029
acid secretion GO:0046717 48 0.029
acute inflammatory response GO:0002526 58 0.029
placenta development GO:0001890 22 0.029
protein maturation GO:0051604 68 0.028
sympathetic nervous system development GO:0048485 1 0.028
response to ethanol GO:0045471 162 0.028
cellular response to peptide GO:1901653 133 0.028
regulation of tolerance induction to nonself antigen GO:0002655 1 0.028
cellular response to organonitrogen compound GO:0071417 197 0.028
gastrulation GO:0007369 2 0.028
organic acid transport GO:0015849 116 0.028
regulation of renin secretion into blood stream GO:1900133 1 0.027
positive regulation of cell migration GO:0030335 96 0.027
positive regulation of long term synaptic potentiation GO:1900273 4 0.027
endothelium development GO:0003158 12 0.027
negative regulation of ion transport GO:0043271 51 0.027
response to dexamethasone GO:0071548 49 0.027
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.027
reactive oxygen species metabolic process GO:0072593 37 0.027
response to ionizing radiation GO:0010212 59 0.027
regulation of muscle organ development GO:0048634 26 0.027
sensory organ development GO:0007423 74 0.027
regulation of response to wounding GO:1903034 69 0.027
regulation of anatomical structure morphogenesis GO:0022603 141 0.027
circulatory system development GO:0072359 134 0.026
monocarboxylic acid metabolic process GO:0032787 152 0.026
response to ketone GO:1901654 182 0.026
cellular response to peptide hormone stimulus GO:0071375 120 0.026
negative regulation of signaling GO:0023057 157 0.026
regulation of protein serine threonine kinase activity GO:0071900 64 0.026
Human
protein complex assembly GO:0006461 263 0.026
regulation of calcium ion transport GO:0051924 77 0.026
positive regulation of neurogenesis GO:0050769 165 0.026
organic hydroxy compound biosynthetic process GO:1901617 51 0.026
cellular amino acid metabolic process GO:0006520 107 0.026
regulation of cell growth GO:0001558 85 0.026
single organism organelle organization GO:1902589 180 0.026
regulation of amine transport GO:0051952 54 0.026
metal ion homeostasis GO:0055065 186 0.026
negative regulation of cell death GO:0060548 229 0.025
renal filtration GO:0097205 10 0.025
positive regulation of locomotion GO:0040017 102 0.025
activation of protein kinase activity GO:0032147 47 0.025
positive regulation of the force of heart contraction by norepinephrine GO:0003061 1 0.025
response to gamma radiation GO:0010332 24 0.025
intracellular receptor signaling pathway GO:0030522 35 0.025
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure GO:0002025 1 0.025
ras protein signal transduction GO:0007265 29 0.025
response to radiation GO:0009314 137 0.025
muscle organ development GO:0007517 50 0.025
regulation of muscle tissue development GO:1901861 25 0.025
mesoderm development GO:0007498 2 0.024
monovalent inorganic cation transport GO:0015672 172 0.024
renal system process GO:0003014 40 0.024
regulation of growth GO:0040008 105 0.024
regulation of cellular amine metabolic process GO:0033238 8 0.024
positive regulation of blood pressure by epinephrine norepinephrine GO:0003321 2 0.024
mesenchymal cell proliferation GO:0010463 4 0.024
cellular macromolecule localization GO:0070727 122 0.024
dendrite morphogenesis GO:0048813 43 0.024
anatomical structure formation involved in morphogenesis GO:0048646 83 0.024
negative regulation of phosphate metabolic process GO:0045936 80 0.023
Human
macromolecular complex subunit organization GO:0043933 339 0.023
rhythmic process GO:0048511 156 0.023
regulation of membrane potential GO:0042391 110 0.023
regulation of body fluid levels GO:0050878 90 0.023
positive regulation of protein kinase activity GO:0045860 73 0.023
tissue regeneration GO:0042246 36 0.023
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.023
regulation of organ morphogenesis GO:2000027 22 0.023
cardiac muscle contraction GO:0060048 27 0.023
regulation of transmembrane transport GO:0034762 122 0.022
regulation of protein localization GO:0032880 81 0.022
negative regulation of innate immune response GO:0045824 4 0.022
negative regulation of amine transport GO:0051953 24 0.022
response to interleukin 1 GO:0070555 55 0.022
multicellular organism growth GO:0035264 1 0.022
cellular divalent inorganic cation homeostasis GO:0072503 162 0.022
cytoplasmic transport GO:0016482 115 0.021
hair cycle GO:0042633 3 0.021
response to heat GO:0009408 60 0.021
regulation of cardiac muscle tissue development GO:0055024 12 0.021
regulation of appetite GO:0032098 8 0.021
s shaped body morphogenesis GO:0072050 2 0.021
actin filament based process GO:0030029 86 0.021
hormone secretion GO:0046879 115 0.021
cation transmembrane transport GO:0098655 263 0.021
carbohydrate derivative catabolic process GO:1901136 147 0.021
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.021
muscle cell differentiation GO:0042692 52 0.021
regulation of cellular response to stress GO:0080135 49 0.021
multicellular organismal signaling GO:0035637 44 0.021
cellular response to lipopolysaccharide GO:0071222 55 0.021
regulation of dna metabolic process GO:0051052 60 0.021
blood circulation GO:0008015 183 0.021
vasoconstriction GO:0042310 54 0.021
establishment of protein localization GO:0045184 141 0.020
male gonad development GO:0008584 59 0.020
hair cycle process GO:0022405 2 0.020
single organism catabolic process GO:0044712 283 0.020
single organism cellular localization GO:1902580 102 0.020
regulation of epithelial cell proliferation GO:0050678 49 0.020
Human
anterior posterior pattern specification GO:0009952 1 0.020
cellular response to ketone GO:1901655 51 0.020
cell morphogenesis involved in differentiation GO:0000904 119 0.020
response to cold GO:0009409 29 0.020
circadian rhythm GO:0007623 88 0.020

Cdkn2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022