Rattus norvegicus

0 known processes

Cdkn3

cyclin-dependent kinase inhibitor 3

Cdkn3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cardiac muscle cell proliferation GO:0060038 6 0.524
meiosis i GO:0007127 2 0.468
cellular response to iron iii ion GO:0071283 3 0.445
positive regulation of cardiac muscle cell proliferation GO:0060045 4 0.331
regulation of cardiac muscle tissue development GO:0055024 12 0.292
response to ddt GO:0046680 1 0.225
cell cycle dna replication GO:0044786 1 0.221
cellular response to stress GO:0033554 269 0.177
response to inorganic substance GO:0010035 377 0.166
regulation of cell proliferation GO:0042127 359 0.165
positive regulation of multicellular organismal process GO:0051240 387 0.158
response to transition metal nanoparticle GO:1990267 122 0.143
regulation of heart growth GO:0060420 12 0.137
ventricular cardiac muscle cell development GO:0055015 2 0.134
regulation of mrna 3 end processing GO:0031440 1 0.132
single organism biosynthetic process GO:0044711 342 0.126
chromosome segregation GO:0007059 2 0.124
protein complex assembly GO:0006461 263 0.122
dna packaging GO:0006323 4 0.115
cellular response to oxygen containing compound GO:1901701 386 0.108
cell cycle checkpoint GO:0000075 2 0.103
chromosome condensation GO:0030261 3 0.103
macromolecular complex assembly GO:0065003 273 0.098
cardiac muscle cell development GO:0055013 16 0.096
organ growth GO:0035265 24 0.091
mitotic spindle organization GO:0007052 2 0.088
ventricular cardiac muscle cell differentiation GO:0055012 2 0.082
striated muscle cell proliferation GO:0014855 9 0.080
sister chromatid segregation GO:0000819 1 0.079
positive regulation of protein metabolic process GO:0051247 178 0.079
regulation of muscle tissue development GO:1901861 25 0.076
positive regulation of developmental process GO:0051094 283 0.076
regulation of organ growth GO:0046620 13 0.075
mitotic sister chromatid segregation GO:0000070 1 0.074
cellular protein localization GO:0034613 122 0.073
microtubule anchoring GO:0034453 1 0.073
regeneration GO:0031099 163 0.073
organelle organization GO:0006996 266 0.073
circulatory system development GO:0072359 134 0.073
negative regulation of metabolic process GO:0009892 331 0.072
regulation of molecular function GO:0065009 398 0.071
macromolecular complex subunit organization GO:0043933 339 0.071
regulation of multicellular organismal development GO:2000026 376 0.069
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.067
muscle cell proliferation GO:0033002 84 0.066
response to estrogen GO:0043627 232 0.066
metaphase anaphase transition of mitotic cell cycle GO:0007091 1 0.066
regulation of phosphorus metabolic process GO:0051174 349 0.064
spindle organization GO:0007051 2 0.064
response to metal ion GO:0010038 253 0.062
regulation of rna metabolic process GO:0051252 391 0.062
response to biotic stimulus GO:0009607 226 0.062
transcription dna templated GO:0006351 377 0.061
regulation of organelle organization GO:0033043 80 0.060
regulation of catalytic activity GO:0050790 304 0.059
regulation of cardiac muscle tissue growth GO:0055021 12 0.058
muscle tissue development GO:0060537 58 0.057
reproductive process GO:0022414 372 0.057
muscle structure development GO:0061061 87 0.057
cellular response to acid chemical GO:0071229 75 0.056
tissue development GO:0009888 252 0.056
regulation of cellular component organization GO:0051128 368 0.056
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.055
apoptotic process GO:0006915 381 0.055
positive regulation of heart growth GO:0060421 9 0.055
histone phosphorylation GO:0016572 6 0.054
negative regulation of phosphate metabolic process GO:0045936 80 0.054
mitotic cell cycle phase transition GO:0044772 20 0.054
regulation of muscle organ development GO:0048634 26 0.053
wound healing GO:0042060 122 0.051
regulation of transcription dna templated GO:0006355 374 0.051
cardiac cell development GO:0055006 16 0.051
regulation of phosphate metabolic process GO:0019220 349 0.050
negative regulation of cell death GO:0060548 229 0.050
response to insecticide GO:0017085 21 0.050
developmental growth GO:0048589 100 0.047
negative regulation of cell cycle phase transition GO:1901988 4 0.047
response to oxidative stress GO:0006979 186 0.047
regulation of striated muscle tissue development GO:0016202 25 0.045
regulation of chromosome segregation GO:0051983 1 0.045
dna metabolic process GO:0006259 96 0.045
multicellular organismal reproductive process GO:0048609 233 0.045
positive regulation of cellular protein metabolic process GO:0032270 167 0.044
response to toxic substance GO:0009636 133 0.043
protein complex biogenesis GO:0070271 263 0.043
growth GO:0040007 165 0.043
response to wounding GO:0009611 254 0.043
positive regulation of rna metabolic process GO:0051254 203 0.041
positive regulation of phosphorus metabolic process GO:0010562 262 0.041
response to peptide GO:1901652 292 0.041
heart growth GO:0060419 20 0.041
positive regulation of cell proliferation GO:0008284 249 0.040
cellular component assembly GO:0022607 360 0.040
rna metabolic process GO:0016070 406 0.039
positive regulation of protein modification process GO:0031401 142 0.039
protein complex subunit organization GO:0071822 302 0.039
mitotic sister chromatid separation GO:0051306 1 0.039
maintenance of location GO:0051235 17 0.038
response to mechanical stimulus GO:0009612 134 0.038
cardiovascular system development GO:0072358 134 0.038
cellular component biogenesis GO:0044085 368 0.038
negative regulation of cellular biosynthetic process GO:0031327 161 0.037
meiotic cell cycle process GO:1903046 3 0.037
cardiocyte differentiation GO:0035051 22 0.037
programmed cell death GO:0012501 392 0.037
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.036
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 1 0.034
epithelium development GO:0060429 96 0.034
positive regulation of histone phosphorylation GO:0033129 3 0.033
regulation of chromosome organization GO:0033044 9 0.033
negative regulation of apoptotic process GO:0043066 181 0.032
cellular response to metal ion GO:0071248 55 0.032
regulation of cell differentiation GO:0045595 320 0.032
multicellular organism reproduction GO:0032504 233 0.032
single organism reproductive process GO:0044702 297 0.032
metaphase anaphase transition of cell cycle GO:0044784 1 0.032
positive regulation of triglyceride metabolic process GO:0090208 4 0.031
protein localization to chromosome centromeric region GO:0071459 1 0.031
response to oxygen levels GO:0070482 265 0.031
single organism organelle organization GO:1902589 180 0.031
cellular component movement GO:0006928 248 0.031
regulation of protein metabolic process GO:0051246 289 0.030
cytoskeleton dependent cytokinesis GO:0061640 2 0.030
defense response GO:0006952 194 0.030
regulation of growth GO:0040008 105 0.030
brain development GO:0007420 247 0.030
positive regulation of biosynthetic process GO:0009891 319 0.029
mitotic cell cycle GO:0000278 49 0.029
macromolecule localization GO:0033036 252 0.029
rna biosynthetic process GO:0032774 380 0.029
single organism catabolic process GO:0044712 283 0.028
negative regulation of programmed cell death GO:0043069 183 0.028
protein phosphorylation GO:0006468 345 0.028
centrosome cycle GO:0007098 1 0.028
cellular catabolic process GO:0044248 295 0.028
organic cyclic compound catabolic process GO:1901361 175 0.028
regulation of programmed cell death GO:0043067 341 0.027
protein localization GO:0008104 191 0.027
regulation of nucleic acid templated transcription GO:1903506 380 0.027
response to organophosphorus GO:0046683 102 0.027
regulation of neuron projection development GO:0010975 161 0.027
negative regulation of macromolecule metabolic process GO:0010605 260 0.027
cellular response to organic cyclic compound GO:0071407 202 0.027
head development GO:0060322 247 0.027
regulation of nervous system development GO:0051960 264 0.026
cellular homeostasis GO:0019725 252 0.026
reproduction GO:0000003 245 0.026
anterior posterior pattern specification GO:0009952 1 0.026
cellular response to lipid GO:0071396 201 0.025
nucleic acid templated transcription GO:0097659 379 0.025
catabolic process GO:0009056 351 0.025
negative regulation of phosphorus metabolic process GO:0010563 80 0.025
regulation of catabolic process GO:0009894 113 0.025
response to decreased oxygen levels GO:0036293 237 0.025
cellular response to inorganic substance GO:0071241 65 0.025
regulation of developmental growth GO:0048638 45 0.025
regulation of apoptotic process GO:0042981 335 0.025
regulation of neuron differentiation GO:0045664 208 0.025
response to hypoxia GO:0001666 231 0.025
centrosome organization GO:0051297 1 0.025
sexual reproduction GO:0019953 148 0.025
positive regulation of rna biosynthetic process GO:1902680 197 0.024
response to amine GO:0014075 46 0.024
positive regulation of gene expression GO:0010628 244 0.024
response to acid chemical GO:0001101 222 0.024
striated muscle cell development GO:0055002 26 0.024
tube development GO:0035295 89 0.024
carbohydrate derivative metabolic process GO:1901135 346 0.024
cellular response to hormone stimulus GO:0032870 247 0.023
cardiac muscle tissue development GO:0048738 26 0.023
covalent chromatin modification GO:0016569 30 0.023
regulation of cellular protein metabolic process GO:0032268 267 0.023
positive regulation of molecular function GO:0044093 230 0.023
regulation of neurogenesis GO:0050767 247 0.023
positive regulation of cellular biosynthetic process GO:0031328 295 0.023
macromolecule catabolic process GO:0009057 58 0.023
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.022
cellular macromolecule localization GO:0070727 122 0.022
multi organism reproductive process GO:0044703 262 0.022
ras protein signal transduction GO:0007265 29 0.022
cellular amine metabolic process GO:0044106 38 0.022
developmental process involved in reproduction GO:0003006 159 0.022
g1 s transition of mitotic cell cycle GO:0000082 12 0.021
tissue regeneration GO:0042246 36 0.021
positive regulation of protein phosphorylation GO:0001934 135 0.021
positive regulation of growth GO:0045927 55 0.021
positive regulation of lipid catabolic process GO:0050996 4 0.021
positive regulation of muscle organ development GO:0048636 13 0.021
intracellular signal transduction GO:0035556 314 0.021
cell projection organization GO:0030030 302 0.021
neuron differentiation GO:0030182 368 0.021
reproductive structure development GO:0048608 128 0.021
striated muscle tissue development GO:0014706 58 0.021
response to other organism GO:0051707 220 0.021
mrna metabolic process GO:0016071 20 0.020
spermatogenesis GO:0007283 99 0.020
regulation of chromatin binding GO:0035561 3 0.020
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.020
positive regulation of cellular catabolic process GO:0031331 71 0.020
positive regulation of developmental growth GO:0048639 29 0.020
chromatin organization GO:0006325 34 0.020
regulation of cell development GO:0060284 263 0.020
positive regulation of nervous system development GO:0051962 178 0.020
positive regulation of cellular component organization GO:0051130 200 0.020
regulation of intracellular signal transduction GO:1902531 218 0.020
anatomical structure morphogenesis GO:0009653 298 0.019
aromatic compound catabolic process GO:0019439 168 0.019
chromatin modification GO:0016568 33 0.019
positive regulation of mrna metabolic process GO:1903313 4 0.019
positive regulation of cell development GO:0010720 176 0.019
nucleobase containing compound catabolic process GO:0034655 152 0.019
regulation of lipid metabolic process GO:0019216 68 0.019
transcription from rna polymerase ii promoter GO:0006366 252 0.018
regulation of signal transduction GO:0009966 318 0.018
cell morphogenesis GO:0000902 142 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
muscle cell differentiation GO:0042692 52 0.018
negative regulation of cellular protein metabolic process GO:0032269 106 0.018
nucleobase containing small molecule metabolic process GO:0055086 316 0.018
cytoskeleton organization GO:0007010 111 0.018
cellular response to endogenous stimulus GO:0071495 377 0.018
response to external biotic stimulus GO:0043207 221 0.017
vesicle mediated transport GO:0016192 181 0.017
negative regulation of protein metabolic process GO:0051248 114 0.017
heterocycle catabolic process GO:0046700 167 0.017
cellular response to nitrogen compound GO:1901699 210 0.017
regulation of protein phosphorylation GO:0001932 183 0.017
cellular component morphogenesis GO:0032989 155 0.017
cellular nitrogen compound catabolic process GO:0044270 163 0.017
muscle organ development GO:0007517 50 0.016
regulation of phosphorylation GO:0042325 248 0.016
regulation of protein modification process GO:0031399 194 0.016
response to fatty acid GO:0070542 65 0.016
negative regulation of phosphorylation GO:0042326 57 0.016
cardiac muscle tissue growth GO:0055017 20 0.016
cellular ketone metabolic process GO:0042180 51 0.016
regulation of protein kinase activity GO:0045859 105 0.016
organophosphate metabolic process GO:0019637 370 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
chromosome separation GO:0051304 1 0.016
organophosphate catabolic process GO:0046434 148 0.015
regulation of kinase activity GO:0043549 117 0.015
amine metabolic process GO:0009308 38 0.015
response to iron iii ion GO:0010041 6 0.015
regulation of cell maturation GO:1903429 3 0.015
cellular response to oxidative stress GO:0034599 76 0.015
organic substance catabolic process GO:1901575 316 0.015
regulation of cellular catabolic process GO:0031329 101 0.015
tube formation GO:0035148 3 0.015
negative regulation of gene expression GO:0010629 199 0.015
mitotic cell cycle checkpoint GO:0007093 1 0.015
cell growth GO:0016049 104 0.015
positive regulation of transcription dna templated GO:0045893 197 0.015
camera type eye development GO:0043010 48 0.015
dna replication GO:0006260 37 0.015
response to peptide hormone GO:0043434 278 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
dna integrity checkpoint GO:0031570 2 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
cell cycle g1 s phase transition GO:0044843 13 0.014
microtubule cytoskeleton organization GO:0000226 25 0.014
negative regulation of molecular function GO:0044092 133 0.014
negative regulation of cell proliferation GO:0008285 119 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
axis specification GO:0009798 4 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
reproductive system development GO:0061458 128 0.013
regulation of rna biosynthetic process GO:2001141 381 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
cellular chemical homeostasis GO:0055082 247 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
negative regulation of chromosome organization GO:2001251 1 0.013
single organism intracellular transport GO:1902582 166 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
chromosome organization GO:0051276 36 0.013
regulation of cell cycle GO:0051726 73 0.013
regulation of transferase activity GO:0051338 123 0.013
regulation of mitotic sister chromatid segregation GO:0033047 1 0.013
positive regulation of organelle organization GO:0010638 48 0.013
positive regulation of phosphate metabolic process GO:0045937 262 0.013
regulation of cellular amine metabolic process GO:0033238 8 0.013
carboxylic acid metabolic process GO:0019752 289 0.013
negative regulation of response to stimulus GO:0048585 155 0.013
heart development GO:0007507 72 0.013
establishment of protein localization GO:0045184 141 0.013
cell cycle phase transition GO:0044770 21 0.013
regulation of cellular amino acid metabolic process GO:0006521 2 0.013
regulation of cell projection organization GO:0031344 175 0.013
nucleotide metabolic process GO:0009117 279 0.013
male gamete generation GO:0048232 99 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
cellular response to iron ion GO:0071281 5 0.012
cell motility GO:0048870 202 0.012
purine containing compound metabolic process GO:0072521 253 0.012
cellular amino acid metabolic process GO:0006520 107 0.012
sex differentiation GO:0007548 113 0.012
response to camp GO:0051591 91 0.012
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 3 0.012
guanosine containing compound metabolic process GO:1901068 74 0.012
locomotion GO:0040011 237 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
gamete generation GO:0007276 124 0.012
positive regulation of cell differentiation GO:0045597 217 0.012
g2 m transition of mitotic cell cycle GO:0000086 6 0.012
single organism nuclear import GO:1902593 35 0.012
neuron development GO:0048666 286 0.012
response to nutrient levels GO:0031667 370 0.012
negative regulation of transcription dna templated GO:0045892 116 0.012
homeostatic process GO:0042592 331 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
protein localization to organelle GO:0033365 57 0.011
histone serine phosphorylation GO:0035404 1 0.011
chemical homeostasis GO:0048878 292 0.011
regulation of nuclear cell cycle dna replication GO:0033262 1 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
cell cycle GO:0007049 101 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
response to temperature stimulus GO:0009266 94 0.011
response to estradiol GO:0032355 164 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
male meiosis GO:0007140 1 0.011
cellular response to oxygen levels GO:0071453 60 0.011
protein dephosphorylation GO:0006470 38 0.011
response to axon injury GO:0048678 59 0.011
response to ethanol GO:0045471 162 0.011
intracellular protein transport GO:0006886 79 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.011
negative regulation of protein modification process GO:0031400 52 0.011
negative regulation of protein phosphorylation GO:0001933 44 0.011
regulation of meiotic cell cycle GO:0051445 3 0.011
regulation of response to stress GO:0080134 126 0.011
microtubule organizing center organization GO:0031023 1 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
lipid metabolic process GO:0006629 283 0.010
positive regulation of cytoskeleton organization GO:0051495 26 0.010
eye development GO:0001654 50 0.010
positive regulation of catabolic process GO:0009896 78 0.010
positive regulation of catalytic activity GO:0043085 184 0.010
oxoacid metabolic process GO:0043436 290 0.010
cellular response to biotic stimulus GO:0071216 59 0.010
negative regulation of cellular metabolic process GO:0031324 281 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.010
nuclear division GO:0000280 22 0.010
positive regulation of cell death GO:0010942 184 0.010
negative regulation of cell communication GO:0010648 158 0.010
digestive tract development GO:0048565 39 0.010
positive regulation of apoptotic process GO:0043065 154 0.010
neuronal stem cell division GO:0036445 1 0.010
positive regulation of neurogenesis GO:0050769 165 0.010

Cdkn3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.020