Rattus norvegicus

0 known processes

Ceacam3

carcinoembryonic antigen-related cell adhesion molecule 3

(Aliases: Cgm1,CGM4AA,Cgm4,Cea,MGC114355,RATCGM4AA,Ceacam5,Cear,RATCEAA)

Ceacam3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to estrogen GO:0043627 232 0.384
transmembrane transport GO:0055085 412 0.374
positive regulation of signaling GO:0023056 270 0.263
Rat
inorganic cation transmembrane transport GO:0098662 202 0.255
regulation of phosphorus metabolic process GO:0051174 349 0.238
Rat
positive regulation of signal transduction GO:0009967 175 0.210
Rat
reproductive process GO:0022414 372 0.207
Rat
central nervous system development GO:0007417 311 0.201
response to histamine GO:0034776 3 0.187
brain development GO:0007420 247 0.186
cellular response to organic cyclic compound GO:0071407 202 0.179
regulation of multicellular organismal development GO:2000026 376 0.174
ion transmembrane transport GO:0034220 365 0.171
protein phosphorylation GO:0006468 345 0.164
Rat
macromolecular complex subunit organization GO:0043933 339 0.162
Rat
regulation of phosphorylation GO:0042325 248 0.160
Rat
response to toxic substance GO:0009636 133 0.154
cation transport GO:0006812 382 0.153
mapk cascade GO:0000165 140 0.153
Rat
positive regulation of protein phosphorylation GO:0001934 135 0.136
Rat
regulation of cellular protein metabolic process GO:0032268 267 0.133
Rat
response to nutrient levels GO:0031667 370 0.129
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.126
blood circulation GO:0008015 183 0.125
response to other organism GO:0051707 220 0.125
response to hypoxia GO:0001666 231 0.124
regulation of phosphate metabolic process GO:0019220 349 0.112
Rat
regulation of molecular function GO:0065009 398 0.111
Rat
response to extracellular stimulus GO:0009991 380 0.108
head development GO:0060322 247 0.103
positive regulation of cell communication GO:0010647 271 0.103
Rat
response to decreased oxygen levels GO:0036293 237 0.103
regulation of cell proliferation GO:0042127 359 0.102
carboxylic acid metabolic process GO:0019752 289 0.096
gland development GO:0048732 155 0.096
response to estradiol GO:0032355 164 0.094
single organism reproductive process GO:0044702 297 0.089
response to lipopolysaccharide GO:0032496 191 0.086
regulation of intracellular signal transduction GO:1902531 218 0.084
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.078
anion transmembrane transport GO:0098656 77 0.078
cellular response to lipid GO:0071396 201 0.077
positive regulation of phosphate metabolic process GO:0045937 262 0.077
Rat
response to radiation GO:0009314 137 0.075
potassium ion transport GO:0006813 97 0.075
cellular response to endogenous stimulus GO:0071495 377 0.072
anion transport GO:0006820 178 0.071
regulation of cyclase activity GO:0031279 21 0.068
regulation of cell development GO:0060284 263 0.067
regulation of kinase activity GO:0043549 117 0.066
Rat
response to growth factor GO:0070848 189 0.066
cellular component biogenesis GO:0044085 368 0.065
Rat
regulation of ion transport GO:0043269 245 0.064
cellular response to histamine GO:0071420 3 0.064
positive regulation of phosphorus metabolic process GO:0010562 262 0.063
Rat
regulation of protein modification process GO:0031399 194 0.063
Rat
organic acid metabolic process GO:0006082 292 0.063
protein complex biogenesis GO:0070271 263 0.063
Rat
long term synaptic potentiation GO:0060291 21 0.062
response to nutrient GO:0007584 248 0.061
response to ketone GO:1901654 182 0.060
cellular component assembly GO:0022607 360 0.060
Rat
response to external biotic stimulus GO:0043207 221 0.059
response to glucocorticoid GO:0051384 223 0.058
establishment of protein localization GO:0045184 141 0.058
cellular amino acid metabolic process GO:0006520 107 0.056
amine metabolic process GO:0009308 38 0.055
response to camp GO:0051591 91 0.055
macromolecular complex assembly GO:0065003 273 0.055
Rat
circulatory system process GO:0003013 183 0.054
cellular ketone metabolic process GO:0042180 51 0.054
tissue development GO:0009888 252 0.053
protein transport GO:0015031 132 0.053
monovalent inorganic cation transport GO:0015672 172 0.052
multicellular organism reproduction GO:0032504 233 0.051
negative regulation of cell death GO:0060548 229 0.049
synaptic transmission glycinergic GO:0060012 2 0.048
metal ion transport GO:0030001 289 0.048
multicellular organismal reproductive process GO:0048609 233 0.048
fatty acid derivative metabolic process GO:1901568 38 0.047
positive regulation of cell proliferation GO:0008284 249 0.047
regulation of cellular amine metabolic process GO:0033238 8 0.046
negative regulation of chronic inflammatory response GO:0002677 2 0.046
cellular response to growth factor stimulus GO:0071363 162 0.046
apoptotic process GO:0006915 381 0.046
oxoacid metabolic process GO:0043436 290 0.045
cellular response to steroid hormone stimulus GO:0071383 93 0.045
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.044
response to mechanical stimulus GO:0009612 134 0.044
steroid biosynthetic process GO:0006694 48 0.044
regulation of homeostatic process GO:0032844 101 0.043
regulation of transferase activity GO:0051338 123 0.043
Rat
regulation of signal transduction GO:0009966 318 0.043
Rat
response to molecule of bacterial origin GO:0002237 194 0.043
regulation of cellular amino acid metabolic process GO:0006521 2 0.042
multi organism reproductive process GO:0044703 262 0.042
Rat
rna biosynthetic process GO:0032774 380 0.042
response to organophosphorus GO:0046683 102 0.042
positive regulation of protein transport GO:0051222 41 0.042
inorganic ion transmembrane transport GO:0098660 229 0.042
positive regulation of developmental process GO:0051094 283 0.041
regulation of mapk cascade GO:0043408 116 0.041
Rat
protein heterooligomerization GO:0051291 89 0.041
protein complex assembly GO:0006461 263 0.040
Rat
protein oligomerization GO:0051259 191 0.040
Rat
peptidyl amino acid modification GO:0018193 126 0.040
positive regulation of cellular amine metabolic process GO:0033240 3 0.040
response to biotic stimulus GO:0009607 226 0.039
response to oxygen levels GO:0070482 265 0.038
cell type specific apoptotic process GO:0097285 134 0.038
anatomical structure morphogenesis GO:0009653 298 0.038
cellular response to nitrogen compound GO:1901699 210 0.038
response to inorganic substance GO:0010035 377 0.037
regulation of protein metabolic process GO:0051246 289 0.037
Rat
single organism biosynthetic process GO:0044711 342 0.037
sex differentiation GO:0007548 113 0.036
cellular amine metabolic process GO:0044106 38 0.036
purine ribonucleotide metabolic process GO:0009150 227 0.036
regulation of ion transmembrane transport GO:0034765 121 0.036
male sex differentiation GO:0046661 64 0.036
cellular macromolecule localization GO:0070727 122 0.036
positive regulation of biosynthetic process GO:0009891 319 0.036
response to transition metal nanoparticle GO:1990267 122 0.035
reproductive structure development GO:0048608 128 0.035
development of primary sexual characteristics GO:0045137 107 0.034
choline transport GO:0015871 4 0.034
cellular response to hormone stimulus GO:0032870 247 0.034
regulation of protein kinase activity GO:0045859 105 0.034
Rat
response to antibiotic GO:0046677 39 0.033
cation transmembrane transport GO:0098655 263 0.033
regulation of protein secretion GO:0050708 28 0.033
regulation of nervous system development GO:0051960 264 0.033
positive regulation of nervous system development GO:0051962 178 0.033
response to ethanol GO:0045471 162 0.032
regulation of map kinase activity GO:0043405 53 0.032
Rat
regulation of establishment of protein localization GO:0070201 69 0.032
nucleobase containing small molecule metabolic process GO:0055086 316 0.032
intracellular signal transduction GO:0035556 314 0.032
Rat
forebrain development GO:0030900 98 0.031
kidney development GO:0001822 67 0.031
trichloroethylene metabolic process GO:0018979 1 0.031
regulation of cellular ketone metabolic process GO:0010565 27 0.031
regulation of epithelial cell proliferation GO:0050678 49 0.030
nucleic acid templated transcription GO:0097659 379 0.030
positive regulation of cellular protein metabolic process GO:0032270 167 0.030
Rat
multi multicellular organism process GO:0044706 138 0.030
Rat
lipid metabolic process GO:0006629 283 0.029
growth GO:0040007 165 0.029
synapse assembly GO:0007416 29 0.029
hepaticobiliary system development GO:0061008 90 0.029
response to acid chemical GO:0001101 222 0.029
cellular response to lipopolysaccharide GO:0071222 55 0.028
positive regulation of intracellular signal transduction GO:1902533 138 0.028
Rat
positive regulation of cell development GO:0010720 176 0.028
organonitrogen compound biosynthetic process GO:1901566 167 0.028
regulation of cell differentiation GO:0045595 320 0.028
sequestering of calcium ion GO:0051208 8 0.027
positive regulation of protein metabolic process GO:0051247 178 0.027
Rat
sexual reproduction GO:0019953 148 0.027
response to bacterium GO:0009617 200 0.027
rhythmic process GO:0048511 156 0.026
reproductive system development GO:0061458 128 0.026
regulation of ossification GO:0030278 32 0.026
renal system development GO:0072001 67 0.026
regulation of adenylate cyclase activity GO:0045761 18 0.026
negative regulation of signaling GO:0023057 157 0.026
developmental process involved in reproduction GO:0003006 159 0.026
regulation of protein phosphorylation GO:0001932 183 0.025
Rat
protein homooligomerization GO:0051260 91 0.025
Rat
negative regulation of alpha beta t cell activation GO:0046636 1 0.025
response to alkaloid GO:0043279 132 0.025
signal transduction by phosphorylation GO:0023014 144 0.025
Rat
regulation of apoptotic process GO:0042981 335 0.025
response to peptide hormone GO:0043434 278 0.025
maintenance of location GO:0051235 17 0.024
regulation of neuron death GO:1901214 115 0.024
cyclic nucleotide metabolic process GO:0009187 80 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.024
response to cytokine GO:0034097 215 0.024
reproduction GO:0000003 245 0.024
g protein coupled receptor signaling pathway GO:0007186 242 0.024
sodium ion transport GO:0006814 82 0.024
cytosolic calcium ion homeostasis GO:0051480 140 0.024
cellular chemical homeostasis GO:0055082 247 0.024
central nervous system neuron development GO:0021954 5 0.023
carbohydrate derivative biosynthetic process GO:1901137 124 0.023
response to purine containing compound GO:0014074 126 0.023
muscle system process GO:0003012 115 0.023
cellular ion homeostasis GO:0006873 184 0.023
ribose phosphate metabolic process GO:0019693 235 0.023
regulation of catalytic activity GO:0050790 304 0.023
Rat
limbic system development GO:0021761 38 0.023
purine containing compound metabolic process GO:0072521 253 0.022
negative regulation of cell communication GO:0010648 158 0.022
synaptic transmission GO:0007268 235 0.022
regulation of cellular component organization GO:0051128 368 0.022
vasculature development GO:0001944 70 0.022
positive regulation of cell differentiation GO:0045597 217 0.022
learning or memory GO:0007611 90 0.022
regulation of programmed cell death GO:0043067 341 0.022
nitrogen compound transport GO:0071705 229 0.022
release of sequestered calcium ion into cytosol GO:0051209 25 0.022
negative regulation of multicellular organismal process GO:0051241 203 0.022
positive regulation of phosphorylation GO:0042327 177 0.022
Rat
regulation of rna metabolic process GO:0051252 391 0.022
regulation of nucleotide metabolic process GO:0006140 117 0.022
organophosphate metabolic process GO:0019637 370 0.021
regulation of anatomical structure morphogenesis GO:0022603 141 0.021
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.021
negative regulation of phosphorus metabolic process GO:0010563 80 0.021
positive regulation of molecular function GO:0044093 230 0.021
Rat
telencephalon development GO:0021537 62 0.021
regulation of hormone levels GO:0010817 187 0.021
organelle organization GO:0006996 266 0.021
camp metabolic process GO:0046058 63 0.021
regulation of the force of heart contraction by chemical signal GO:0003057 2 0.021
protein localization GO:0008104 191 0.021
programmed cell death GO:0012501 392 0.020
negative regulation of molecular function GO:0044092 133 0.020
regulation of synaptic transmission GO:0050804 141 0.020
response to corticosteroid GO:0031960 235 0.020
positive regulation of cell death GO:0010942 184 0.020
rna metabolic process GO:0016070 406 0.020
carboxylic acid transport GO:0046942 115 0.020
ion homeostasis GO:0050801 212 0.020
gamete generation GO:0007276 124 0.020
urogenital system development GO:0001655 78 0.020
negative regulation of homeostatic process GO:0032845 47 0.019
regulation of protein localization GO:0032880 81 0.019
peptidyl tyrosine modification GO:0018212 72 0.019
regulation of secretion GO:0051046 224 0.019
cyclic nucleotide biosynthetic process GO:0009190 63 0.019
purine nucleotide catabolic process GO:0006195 136 0.019
secondary alcohol metabolic process GO:1902652 2 0.019
macromolecule localization GO:0033036 252 0.019
regulation of cellular component biogenesis GO:0044087 86 0.019
regulation of cellular localization GO:0060341 263 0.019
response to metal ion GO:0010038 253 0.019
positive regulation of transport GO:0051050 245 0.019
protein complex subunit organization GO:0071822 302 0.019
Rat
regulation of camp metabolic process GO:0030814 43 0.019
phenol containing compound metabolic process GO:0018958 30 0.019
sequestering of metal ion GO:0051238 9 0.018
aging GO:0007568 241 0.018
ossification GO:0001503 70 0.018
cellular response to stress GO:0033554 269 0.018
leukocyte cell cell adhesion GO:0007159 4 0.018
negative regulation of cellular protein metabolic process GO:0032269 106 0.018
positive regulation of circadian sleep wake cycle wakefulness GO:0010841 2 0.018
positive regulation of mast cell activation GO:0033005 4 0.018
jnk cascade GO:0007254 28 0.018
pallium development GO:0021543 42 0.018
positive regulation of long term synaptic potentiation GO:1900273 4 0.017
peptidyl tyrosine phosphorylation GO:0018108 72 0.017
reactive oxygen species metabolic process GO:0072593 37 0.017
positive regulation of neuron apoptotic process GO:0043525 33 0.017
negative regulation of luteinizing hormone secretion GO:0033685 4 0.017
calcium ion homeostasis GO:0055074 162 0.017
regulation of protein transport GO:0051223 68 0.017
regulation of hydrolase activity GO:0051336 143 0.017
chemosensory behavior GO:0007635 2 0.016
hormone metabolic process GO:0042445 69 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
cytokine production GO:0001816 61 0.016
negative regulation of cell proliferation GO:0008285 119 0.016
male gonad development GO:0008584 59 0.016
positive regulation of response to stimulus GO:0048584 285 0.016
Rat
organic hydroxy compound metabolic process GO:1901615 115 0.016
regulation of long term synaptic potentiation GO:1900271 5 0.016
positive regulation of protein modification process GO:0031401 142 0.016
Rat
negative regulation of signal transduction GO:0009968 83 0.016
single organism intracellular transport GO:1902582 166 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.016
regulation of angiogenesis GO:0045765 39 0.016
regulation of transcription dna templated GO:0006355 374 0.016
monocarboxylic acid transport GO:0015718 52 0.016
cellular cation homeostasis GO:0030003 180 0.016
regulation of neurogenesis GO:0050767 247 0.016
cellular response to molecule of bacterial origin GO:0071219 56 0.015
positive regulation of protein kinase activity GO:0045860 73 0.015
Rat
embryonic pattern specification GO:0009880 1 0.015
somatostatin receptor signaling pathway GO:0038169 4 0.015
cellular protein localization GO:0034613 122 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
regulation of blood vessel size GO:0050880 89 0.015
regulation of circadian sleep wake cycle wakefulness GO:0010840 2 0.015
ovulation cycle GO:0042698 67 0.015
sleep GO:0030431 30 0.015
tube development GO:0035295 89 0.015
negative regulation of metabolic process GO:0009892 331 0.015
salivary gland development GO:0007431 3 0.015
positive regulation of secretion GO:0051047 140 0.015
cellular response to external stimulus GO:0071496 118 0.015
negative regulation of apoptotic process GO:0043066 181 0.015
response to ammonium ion GO:0060359 71 0.015
regulation of ion transmembrane transporter activity GO:0032412 48 0.015
regulation of camp biosynthetic process GO:0030817 38 0.014
cytoskeleton organization GO:0007010 111 0.014
organic hydroxy compound transport GO:0015850 77 0.014
blood vessel development GO:0001568 69 0.014
gonad development GO:0008406 104 0.014
thyroid gland development GO:0030878 1 0.014
regulation of purine nucleotide metabolic process GO:1900542 115 0.014
response to mineralocorticoid GO:0051385 49 0.014
actin cytoskeleton organization GO:0030036 73 0.014
epithelium development GO:0060429 96 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
vasoconstriction GO:0042310 54 0.014
camp biosynthetic process GO:0006171 47 0.014
potassium ion transmembrane transport GO:0071805 71 0.014
regulation of blood circulation GO:1903522 110 0.014
positive regulation of the force of heart contraction by epinephrine GO:0003059 1 0.014
response to testosterone GO:0033574 55 0.014
jak stat cascade GO:0007259 26 0.014
development of primary male sexual characteristics GO:0046546 59 0.014
nucleoside phosphate biosynthetic process GO:1901293 102 0.014
cell cell signaling GO:0007267 335 0.013
actin filament based process GO:0030029 86 0.013
negative regulation of long term synaptic potentiation GO:1900272 1 0.013
purine nucleotide biosynthetic process GO:0006164 83 0.013
regulation of blood pressure GO:0008217 83 0.013
icosanoid metabolic process GO:0006690 38 0.013
regulation of cytoskeleton organization GO:0051493 49 0.013
negative regulation of ion transport GO:0043271 51 0.013
single organism cellular localization GO:1902580 102 0.013
ribonucleotide biosynthetic process GO:0009260 85 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
tumor necrosis factor biosynthetic process GO:0042533 1 0.013
modified amino acid transport GO:0072337 12 0.013
cellular homeostasis GO:0019725 252 0.013
negative regulation of phosphate metabolic process GO:0045936 80 0.013
eye development GO:0001654 50 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.013
cyclic purine nucleotide metabolic process GO:0052652 62 0.013
circadian sleep wake cycle wakefulness GO:0042746 2 0.013
homeostatic process GO:0042592 331 0.013
neuron death GO:0070997 127 0.013
steroid metabolic process GO:0008202 73 0.013
response to carbohydrate GO:0009743 183 0.013
succinate transport GO:0015744 3 0.013
male gamete generation GO:0048232 99 0.013
carbohydrate derivative metabolic process GO:1901135 346 0.013
organic cyclic compound catabolic process GO:1901361 175 0.013
angioblast cell migration GO:0035476 1 0.013
organic anion transport GO:0015711 132 0.013
sodium ion homeostasis GO:0055078 23 0.012
blood vessel morphogenesis GO:0048514 58 0.012
regulation of synaptic plasticity GO:0048167 70 0.012
purine containing compound biosynthetic process GO:0072522 85 0.012
response to progesterone GO:0032570 48 0.012
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 2 0.012
vascular process in circulatory system GO:0003018 96 0.012
regulation of sequestering of calcium ion GO:0051282 26 0.012
regulation of membrane potential GO:0042391 110 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
regulation of intracellular transport GO:0032386 65 0.012
protein localization to organelle GO:0033365 57 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
negative regulation of peptidase activity GO:0010466 38 0.012
angiogenesis GO:0001525 53 0.012
neurological system process GO:0050877 219 0.012
sterol catabolic process GO:0016127 1 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
negative regulation of nad p h oxidase activity GO:0033861 1 0.012
cellular response to glucocorticoid stimulus GO:0071385 68 0.012
nucleotide biosynthetic process GO:0009165 98 0.011
response to calcium ion GO:0051592 59 0.011
nucleotide metabolic process GO:0009117 279 0.011
triglyceride homeostasis GO:0070328 2 0.011
negative regulation of cellular metabolic process GO:0031324 281 0.011
regulation of lyase activity GO:0051339 22 0.011
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.011
positive regulation of gene expression GO:0010628 244 0.011
positive regulation of intracellular transport GO:0032388 39 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
organ regeneration GO:0031100 101 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
muscle organ development GO:0007517 50 0.011
regulation of nucleic acid templated transcription GO:1903506 380 0.011
oxidation reduction process GO:0055114 304 0.011
lipid biosynthetic process GO:0008610 128 0.011
cellular response to oxygen containing compound GO:1901701 386 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
calcitriol biosynthetic process from calciol GO:0036378 2 0.011
cytoplasmic transport GO:0016482 115 0.011
cellular component movement GO:0006928 248 0.011
regulation of tube size GO:0035150 89 0.011
cellular response to biotic stimulus GO:0071216 59 0.011
calcium mediated signaling GO:0019722 23 0.011
synapse organization GO:0050808 46 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
negative regulation of transport GO:0051051 136 0.011
regulation of transmembrane transporter activity GO:0022898 49 0.010
positive regulation of serotonin secretion GO:0014064 1 0.010
positive regulation of epithelial cell proliferation GO:0050679 32 0.010
antibiotic transport GO:0042891 2 0.010
negative regulation of follicle stimulating hormone secretion GO:0046882 3 0.010
insulin secretion GO:0030073 69 0.010
cellular divalent inorganic cation homeostasis GO:0072503 162 0.010
regulation of vasculature development GO:1901342 44 0.010
response to nicotine GO:0035094 51 0.010
positive regulation of neuron death GO:1901216 43 0.010
development of primary female sexual characteristics GO:0046545 56 0.010
inorganic anion transport GO:0015698 41 0.010
positive regulation of mapk cascade GO:0043410 92 0.010
Rat

Ceacam3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.026
obesity DOID:9970 0 0.023
nutrition disease DOID:374 0 0.023
overnutrition DOID:654 0 0.023
acquired metabolic disease DOID:0060158 0 0.023
retinal disease DOID:5679 0 0.015
blindness DOID:1432 0 0.015
sensory system disease DOID:0050155 0 0.015
color blindness DOID:13399 0 0.015
disease of anatomical entity DOID:7 0 0.015
eye and adnexa disease DOID:1492 0 0.015
nervous system disease DOID:863 0 0.015
eye disease DOID:5614 0 0.015
substance dependence DOID:9973 0 0.014
substance related disorder DOID:303 0 0.014
disease of mental health DOID:150 0 0.014
nicotine dependence DOID:0050742 0 0.014
kidney disease DOID:557 0 0.011
nephrogenic diabetes insipidus DOID:12387 0 0.011
impaired renal function disease DOID:11705 0 0.011
urinary system disease DOID:18 0 0.011