Rattus norvegicus

43 known processes

Cenpi

centromere protein I

(Aliases: LRPR1,RNALRP,Fshprh1)

Cenpi biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
programmed cell death GO:0012501 392 0.293
cell cycle GO:0007049 101 0.210
regulation of rna metabolic process GO:0051252 391 0.202
organonitrogen compound biosynthetic process GO:1901566 167 0.177
positive regulation of response to external stimulus GO:0032103 51 0.172
response to cytokine GO:0034097 215 0.171
regulation of phosphorylation GO:0042325 248 0.156
apoptotic process GO:0006915 381 0.147
neuron differentiation GO:0030182 368 0.139
regulation of nucleic acid templated transcription GO:1903506 380 0.135
regulation of programmed cell death GO:0043067 341 0.130
positive regulation of gene expression GO:0010628 244 0.128
response to nutrient GO:0007584 248 0.128
single organism biosynthetic process GO:0044711 342 0.121
cellular response to stress GO:0033554 269 0.116
tetrahydrofolate metabolic process GO:0046653 9 0.111
nucleic acid templated transcription GO:0097659 379 0.109
regulation of proteasomal protein catabolic process GO:0061136 4 0.106
neuron development GO:0048666 286 0.103
intracellular signal transduction GO:0035556 314 0.100
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.090
positive regulation of cellular protein metabolic process GO:0032270 167 0.089
transcription dna templated GO:0006351 377 0.088
ribonucleotide biosynthetic process GO:0009260 85 0.087
head development GO:0060322 247 0.085
positive regulation of multicellular organismal process GO:0051240 387 0.084
central nervous system development GO:0007417 311 0.082
response to extracellular stimulus GO:0009991 380 0.082
mitotic sister chromatid separation GO:0051306 1 0.079
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.079
regulation of molecular function GO:0065009 398 0.076
positive regulation of phosphorus metabolic process GO:0010562 262 0.076
response to nutrient levels GO:0031667 370 0.075
negative regulation of cell death GO:0060548 229 0.073
regulation of transcription dna templated GO:0006355 374 0.072
cellular amino acid metabolic process GO:0006520 107 0.069
anatomical structure morphogenesis GO:0009653 298 0.069
negative regulation of metabolic process GO:0009892 331 0.069
rhythmic process GO:0048511 156 0.068
protein phosphorylation GO:0006468 345 0.068
regulation of protein phosphorylation GO:0001932 183 0.067
regulation of phosphorus metabolic process GO:0051174 349 0.067
carbohydrate derivative biosynthetic process GO:1901137 124 0.066
negative regulation of programmed cell death GO:0043069 183 0.066
regulation of cellular protein metabolic process GO:0032268 267 0.064
macromolecule localization GO:0033036 252 0.063
negative regulation of macromolecule metabolic process GO:0010605 260 0.063
positive regulation of cell motility GO:2000147 97 0.063
carbohydrate derivative metabolic process GO:1901135 346 0.063
pteridine containing compound metabolic process GO:0042558 14 0.062
double strand break repair GO:0006302 1 0.062
regulation of cell development GO:0060284 263 0.061
centrosome organization GO:0051297 1 0.060
positive regulation of cellular biosynthetic process GO:0031328 295 0.059
metaphase anaphase transition of cell cycle GO:0044784 1 0.058
positive regulation of phosphorylation GO:0042327 177 0.058
rna biosynthetic process GO:0032774 380 0.057
cell cycle process GO:0022402 57 0.056
regulation of neurogenesis GO:0050767 247 0.056
positive regulation of phosphate metabolic process GO:0045937 262 0.056
regulation of cell differentiation GO:0045595 320 0.054
regulation of protein metabolic process GO:0051246 289 0.053
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.053
positive regulation of molecular function GO:0044093 230 0.052
single organism reproductive process GO:0044702 297 0.052
regulation of mapk cascade GO:0043408 116 0.051
reproductive process GO:0022414 372 0.051
positive regulation of response to stimulus GO:0048584 285 0.050
metaphase plate congression GO:0051310 1 0.050
positive regulation of developmental process GO:0051094 283 0.049
negative regulation of phosphate metabolic process GO:0045936 80 0.049
response to corticosteroid GO:0031960 235 0.049
regulation of response to stress GO:0080134 126 0.049
cell projection organization GO:0030030 302 0.049
positive regulation of cell migration GO:0030335 96 0.048
ovulation cycle GO:0042698 67 0.048
regulation of cell proliferation GO:0042127 359 0.048
cellular catabolic process GO:0044248 295 0.048
aging GO:0007568 241 0.048
multicellular organismal reproductive process GO:0048609 233 0.048
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.047
mapk cascade GO:0000165 140 0.046
negative regulation of apoptotic process GO:0043066 181 0.046
positive regulation of locomotion GO:0040017 102 0.046
regulation of cell cycle GO:0051726 73 0.045
response to peptide GO:1901652 292 0.044
regulation of rna biosynthetic process GO:2001141 381 0.044
positive regulation of protein kinase activity GO:0045860 73 0.043
negative regulation of rna biosynthetic process GO:1902679 118 0.043
positive regulation of mapk cascade GO:0043410 92 0.043
regulation of multicellular organismal development GO:2000026 376 0.043
nucleotide biosynthetic process GO:0009165 98 0.043
reproduction GO:0000003 245 0.042
regulation of phosphate metabolic process GO:0019220 349 0.042
negative regulation of cell proliferation GO:0008285 119 0.042
small gtpase mediated signal transduction GO:0007264 36 0.041
chromosome segregation GO:0007059 2 0.041
positive regulation of biosynthetic process GO:0009891 319 0.041
cyclic nucleotide metabolic process GO:0009187 80 0.041
negative regulation of cellular biosynthetic process GO:0031327 161 0.041
regulation of anatomical structure size GO:0090066 135 0.040
negative regulation of transcription dna templated GO:0045892 116 0.040
regeneration GO:0031099 163 0.040
positive regulation of cell differentiation GO:0045597 217 0.040
regulation of nervous system development GO:0051960 264 0.040
purine containing compound metabolic process GO:0072521 253 0.039
negative regulation of phosphorus metabolic process GO:0010563 80 0.039
oxoacid metabolic process GO:0043436 290 0.039
organophosphate metabolic process GO:0019637 370 0.039
positive regulation of cell proliferation GO:0008284 249 0.039
tube development GO:0035295 89 0.039
cellular amine metabolic process GO:0044106 38 0.039
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.038
negative regulation of cellular metabolic process GO:0031324 281 0.038
regulation of apoptotic process GO:0042981 335 0.038
regulation of signal transduction GO:0009966 318 0.038
response to glucocorticoid GO:0051384 223 0.037
nucleoside phosphate biosynthetic process GO:1901293 102 0.037
organelle organization GO:0006996 266 0.037
cellular component movement GO:0006928 248 0.037
neurological system process GO:0050877 219 0.037
negative regulation of nucleic acid templated transcription GO:1903507 117 0.037
regulation of transferase activity GO:0051338 123 0.036
ribose phosphate metabolic process GO:0019693 235 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.036
regulation of intracellular signal transduction GO:1902531 218 0.036
single organism organelle organization GO:1902589 180 0.035
regulation of cell projection organization GO:0031344 175 0.035
regulation of hormone secretion GO:0046883 106 0.034
regulation of cell morphogenesis GO:0022604 77 0.034
response to toxic substance GO:0009636 133 0.034
proteolysis GO:0006508 175 0.034
regulation of protein kinase activity GO:0045859 105 0.033
regulation of stress activated mapk cascade GO:0032872 23 0.033
reproductive structure development GO:0048608 128 0.033
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.033
organophosphate biosynthetic process GO:0090407 143 0.033
catabolic process GO:0009056 351 0.033
regulation of neuron projection development GO:0010975 161 0.033
neuron projection development GO:0031175 273 0.032
protein localization GO:0008104 191 0.032
reproductive system development GO:0061458 128 0.032
amine metabolic process GO:0009308 38 0.032
cellular response to endogenous stimulus GO:0071495 377 0.032
positive regulation of signaling GO:0023056 270 0.032
metaphase anaphase transition of mitotic cell cycle GO:0007091 1 0.031
reactive oxygen species metabolic process GO:0072593 37 0.031
microtubule organizing center organization GO:0031023 1 0.031
regulation of neuron differentiation GO:0045664 208 0.031
negative regulation of gene expression GO:0010629 199 0.031
positive regulation of protein metabolic process GO:0051247 178 0.031
regulation of map kinase activity GO:0043405 53 0.030
positive regulation of nucleic acid templated transcription GO:1903508 197 0.030
response to estrogen GO:0043627 232 0.030
regulation of body fluid levels GO:0050878 90 0.030
protein modification by small protein conjugation or removal GO:0070647 35 0.029
brain development GO:0007420 247 0.029
regulation of catalytic activity GO:0050790 304 0.029
negative regulation of cell differentiation GO:0045596 99 0.029
protein autophosphorylation GO:0046777 66 0.029
small molecule biosynthetic process GO:0044283 124 0.029
regulation of cellular amine metabolic process GO:0033238 8 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.029
signal transduction by phosphorylation GO:0023014 144 0.029
regulation of anatomical structure morphogenesis GO:0022603 141 0.028
regulation of behavior GO:0050795 61 0.028
localization of cell GO:0051674 202 0.028
leukocyte migration GO:0050900 38 0.028
transcription from rna polymerase ii promoter GO:0006366 252 0.028
response to amino acid GO:0043200 75 0.028
rna metabolic process GO:0016070 406 0.028
regulation of cellular response to stress GO:0080135 49 0.028
regulation of cell cycle arrest GO:0071156 2 0.028
glycerolipid metabolic process GO:0046486 67 0.028
developmental process involved in reproduction GO:0003006 159 0.027
positive regulation of cellular component organization GO:0051130 200 0.027
regulation of kinase activity GO:0043549 117 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.027
response to ethanol GO:0045471 162 0.027
cellular component assembly GO:0022607 360 0.027
single organism catabolic process GO:0044712 283 0.026
cellular response to oxygen containing compound GO:1901701 386 0.026
positive regulation of cell development GO:0010720 176 0.026
response to tumor necrosis factor GO:0034612 56 0.026
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.026
purine ribonucleotide metabolic process GO:0009150 227 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.025
mitotic spindle organization GO:0007052 2 0.025
cell morphogenesis GO:0000902 142 0.025
cellular component biogenesis GO:0044085 368 0.025
coenzyme metabolic process GO:0006732 86 0.025
positive regulation of apoptotic process GO:0043065 154 0.025
endoplasmic reticulum to cytosol transport GO:1903513 4 0.025
cellular ketone metabolic process GO:0042180 51 0.025
positive regulation of protein modification process GO:0031401 142 0.025
regulation of system process GO:0044057 208 0.025
positive regulation of catalytic activity GO:0043085 184 0.025
cellular protein catabolic process GO:0044257 19 0.024
ras protein signal transduction GO:0007265 29 0.024
negative regulation of transport GO:0051051 136 0.024
positive regulation of transferase activity GO:0051347 81 0.024
positive regulation of cell projection organization GO:0031346 111 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.024
regulation of mitotic sister chromatid separation GO:0010965 1 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.024
cell type specific apoptotic process GO:0097285 134 0.024
response to mineralocorticoid GO:0051385 49 0.024
regulation of sister chromatid segregation GO:0033045 1 0.023
cellular response to tumor necrosis factor GO:0071356 46 0.023
response to heat GO:0009408 60 0.023
mitotic cell cycle GO:0000278 49 0.023
cellular response to organic cyclic compound GO:0071407 202 0.023
lipid metabolic process GO:0006629 283 0.023
positive regulation of rna biosynthetic process GO:1902680 197 0.023
regulation of cellular component organization GO:0051128 368 0.023
centrosome cycle GO:0007098 1 0.023
dna metabolic process GO:0006259 96 0.023
purine ribonucleotide biosynthetic process GO:0009152 81 0.023
cell migration GO:0016477 197 0.023
positive regulation of protein phosphorylation GO:0001934 135 0.022
intracellular transport GO:0046907 185 0.022
regulation of camp metabolic process GO:0030814 43 0.022
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.022
muscle cell proliferation GO:0033002 84 0.022
proteasomal protein catabolic process GO:0010498 8 0.022
female sex differentiation GO:0046660 59 0.022
chemotaxis GO:0006935 66 0.022
positive regulation of cell communication GO:0010647 271 0.022
male meiosis GO:0007140 1 0.022
response to wounding GO:0009611 254 0.022
nucleotide metabolic process GO:0009117 279 0.022
nucleobase containing small molecule metabolic process GO:0055086 316 0.021
response to acid chemical GO:0001101 222 0.021
purine containing compound biosynthetic process GO:0072522 85 0.021
cell cell signaling GO:0007267 335 0.021
cellular component morphogenesis GO:0032989 155 0.021
negative regulation of signaling GO:0023057 157 0.021
secretion GO:0046903 307 0.021
mitotic cell cycle phase transition GO:0044772 20 0.021
positive regulation of kinase activity GO:0033674 77 0.021
stress activated protein kinase signaling cascade GO:0031098 37 0.021
purine nucleotide biosynthetic process GO:0006164 83 0.021
positive regulation of immune system process GO:0002684 90 0.021
response to vitamin GO:0033273 131 0.020
cell projection morphogenesis GO:0048858 123 0.020
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 1 0.020
positive regulation of nervous system development GO:0051962 178 0.020
neuron projection morphogenesis GO:0048812 122 0.020
positive regulation of cyclase activity GO:0031281 15 0.020
wound healing GO:0042060 122 0.020
cellular response to peptide hormone stimulus GO:0071375 120 0.020
regulation of cell motility GO:2000145 131 0.020
protein complex subunit organization GO:0071822 302 0.020
positive regulation of cell death GO:0010942 184 0.020
hepaticobiliary system development GO:0061008 90 0.020
positive regulation of cellular component movement GO:0051272 102 0.020
positive regulation of transcription dna templated GO:0045893 197 0.020
regulation of mitotic sister chromatid segregation GO:0033047 1 0.019
cytoskeleton organization GO:0007010 111 0.019
behavior GO:0007610 205 0.019
cellular response to extracellular stimulus GO:0031668 73 0.019
gliogenesis GO:0042063 93 0.019
glial cell differentiation GO:0010001 65 0.019
macromolecular complex subunit organization GO:0043933 339 0.019
nucleoside phosphate metabolic process GO:0006753 283 0.019
protein catabolic process GO:0030163 30 0.019
camp biosynthetic process GO:0006171 47 0.019
negative regulation of developmental process GO:0051093 125 0.018
cell motility GO:0048870 202 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
cellular modified amino acid biosynthetic process GO:0042398 18 0.018
multi organism reproductive process GO:0044703 262 0.018
growth GO:0040007 165 0.018
response to estradiol GO:0032355 164 0.018
negative regulation of stress activated mapk cascade GO:0032873 4 0.018
negative regulation of nuclear division GO:0051784 1 0.018
organ regeneration GO:0031100 101 0.018
cyclic purine nucleotide metabolic process GO:0052652 62 0.018
ribose phosphate biosynthetic process GO:0046390 87 0.017
negative regulation of protein maturation GO:1903318 47 0.017
protein complex assembly GO:0006461 263 0.017
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.017
carboxylic acid biosynthetic process GO:0046394 83 0.017
regulation of chemotaxis GO:0050920 29 0.017
cellular macromolecule localization GO:0070727 122 0.017
negative regulation of cellular protein metabolic process GO:0032269 106 0.017
negative regulation of stress activated protein kinase signaling cascade GO:0070303 4 0.017
positive regulation of neurogenesis GO:0050769 165 0.017
negative regulation of biosynthetic process GO:0009890 168 0.016
regulation of reactive oxygen species metabolic process GO:2000377 26 0.016
organelle localization GO:0051640 55 0.016
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.016
response to oxygen levels GO:0070482 265 0.016
cellular response to nitrogen compound GO:1901699 210 0.016
sister chromatid segregation GO:0000819 1 0.016
regulation of response to external stimulus GO:0032101 106 0.016
cardiovascular system development GO:0072358 134 0.016
anatomical structure formation involved in morphogenesis GO:0048646 83 0.016
embryo development GO:0009790 49 0.016
locomotion GO:0040011 237 0.016
protein complex biogenesis GO:0070271 263 0.016
negative regulation of rna metabolic process GO:0051253 123 0.016
multicellular organism reproduction GO:0032504 233 0.015
response to inorganic substance GO:0010035 377 0.015
regulation of leukocyte migration GO:0002685 24 0.015
biological adhesion GO:0022610 110 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
kidney development GO:0001822 67 0.015
circulatory system development GO:0072359 134 0.015
negative regulation of cell communication GO:0010648 158 0.015
response to monosaccharide GO:0034284 159 0.015
gland development GO:0048732 155 0.015
response to purine containing compound GO:0014074 126 0.015
positive regulation of neuron projection development GO:0010976 99 0.015
response to mechanical stimulus GO:0009612 134 0.015
cellular modified amino acid metabolic process GO:0006575 61 0.015
negative regulation of neuron differentiation GO:0045665 62 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
negative regulation of cellular component organization GO:0051129 83 0.014
cell cycle checkpoint GO:0000075 2 0.014
positive regulation of epithelial cell proliferation GO:0050679 32 0.014
response to growth factor GO:0070848 189 0.014
mitotic cell cycle process GO:1903047 35 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
negative regulation of protein modification process GO:0031400 52 0.014
regulation of protein serine threonine kinase activity GO:0071900 64 0.014
cellular response to nutrient GO:0031670 30 0.014
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.014
spindle organization GO:0007051 2 0.014
folic acid containing compound metabolic process GO:0006760 10 0.014
camp metabolic process GO:0046058 63 0.014
immune response GO:0006955 104 0.014
regulation of cellular localization GO:0060341 263 0.013
positive regulation of rna metabolic process GO:0051254 203 0.013
hormone secretion GO:0046879 115 0.013
gamete generation GO:0007276 124 0.013
response to peptide hormone GO:0043434 278 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
liver development GO:0001889 90 0.013
renal system development GO:0072001 67 0.013
lipid localization GO:0010876 62 0.013
epithelium development GO:0060429 96 0.013
protein modification by small protein conjugation GO:0032446 31 0.013
regulation of defense response GO:0031347 68 0.013
regulation of protein modification process GO:0031399 194 0.013
negative regulation of cell division GO:0051782 1 0.013
digestive system development GO:0055123 41 0.013
negative regulation of neurogenesis GO:0050768 78 0.013
response to fatty acid GO:0070542 65 0.013
cell part morphogenesis GO:0032990 123 0.013
neuron apoptotic process GO:0051402 88 0.013
lipid biosynthetic process GO:0008610 128 0.012
cellular response to peptide GO:1901653 133 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
macromolecule catabolic process GO:0009057 58 0.012
regulation of camp biosynthetic process GO:0030817 38 0.012
cellular response to nutrient levels GO:0031669 60 0.012
regulation of dendrite development GO:0050773 59 0.012
growth plate cartilage development GO:0003417 2 0.012
macromolecular complex assembly GO:0065003 273 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
regulation of hydrolase activity GO:0051336 143 0.012
gastrulation GO:0007369 2 0.012
response to radiation GO:0009314 137 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
protein processing GO:0016485 68 0.012
negative regulation of phosphorylation GO:0042326 57 0.012
cerebellar purkinje cell layer development GO:0021680 2 0.012
developmental growth GO:0048589 100 0.012
response to progesterone GO:0032570 48 0.012
sexual reproduction GO:0019953 148 0.012
response to axon injury GO:0048678 59 0.012
epithelial cell differentiation GO:0030855 71 0.012
chromosome separation GO:0051304 1 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
response to activity GO:0014823 73 0.012
regulation of cellular component movement GO:0051270 150 0.012
cellular protein localization GO:0034613 122 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
cyclic nucleotide biosynthetic process GO:0009190 63 0.011
activation of protein kinase activity GO:0032147 47 0.011
urogenital system development GO:0001655 78 0.011
histone h3 acetylation GO:0043966 2 0.011
myeloid leukocyte activation GO:0002274 36 0.011
mitotic sister chromatid segregation GO:0000070 1 0.011
neuron death GO:0070997 127 0.011
regulation of cell cycle process GO:0010564 31 0.011
cellular process involved in reproduction in multicellular organism GO:0022412 35 0.011
cytoplasmic transport GO:0016482 115 0.011
organic acid biosynthetic process GO:0016053 83 0.011
circadian rhythm GO:0007623 88 0.011
regulation of cell migration GO:0030334 128 0.011
negative regulation of chromosome organization GO:2001251 1 0.011
negative regulation of protein phosphorylation GO:0001933 44 0.011
regulation of locomotion GO:0040012 148 0.011
response to temperature stimulus GO:0009266 94 0.011
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 3 0.011
homeostatic process GO:0042592 331 0.011
response to vitamin d GO:0033280 34 0.011
positive regulation of synaptic transmission GO:0050806 62 0.011
carbohydrate metabolic process GO:0005975 130 0.011
negative regulation of signal transduction GO:0009968 83 0.011
male gamete generation GO:0048232 99 0.011
regulation of immune system process GO:0002682 123 0.011
meiotic cell cycle process GO:1903046 3 0.011
anion transport GO:0006820 178 0.010
response to ketone GO:1901654 182 0.010
carboxylic acid metabolic process GO:0019752 289 0.010
cellular response to cytokine stimulus GO:0071345 127 0.010
response to indole 3 methanol GO:0071680 2 0.010
peptidyl amino acid modification GO:0018193 126 0.010
ubiquitin dependent protein catabolic process GO:0006511 14 0.010
response to amine GO:0014075 46 0.010
negative regulation of molecular function GO:0044092 133 0.010
chromosome organization GO:0051276 36 0.010
dna recombination GO:0006310 3 0.010
regulation of cyclase activity GO:0031279 21 0.010
cellular response to hormone stimulus GO:0032870 247 0.010
antral ovarian follicle growth GO:0001547 3 0.010
multicellular organism growth GO:0035264 1 0.010
negative regulation of response to stimulus GO:0048585 155 0.010

Cenpi disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.022
disease of cellular proliferation DOID:14566 0 0.022
organ system cancer DOID:0050686 0 0.022
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020