Rattus norvegicus

73 known processes

Chd4

chromodomain helicase DNA binding protein 4

(Aliases: Mi-2)

Chd4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
histone h3 acetylation GO:0043966 2 0.215
organic substance catabolic process GO:1901575 316 0.202
regulation of transcription dna templated GO:0006355 374 0.134
regulation of rna metabolic process GO:0051252 391 0.130
rna metabolic process GO:0016070 406 0.127
rna biosynthetic process GO:0032774 380 0.118
transcription dna templated GO:0006351 377 0.116
cellular component movement GO:0006928 248 0.113
atp metabolic process GO:0046034 72 0.110
double strand break repair GO:0006302 1 0.099
nucleobase containing small molecule metabolic process GO:0055086 316 0.098
purine nucleotide metabolic process GO:0006163 229 0.093
nucleosome organization GO:0034728 1 0.092
nucleic acid templated transcription GO:0097659 379 0.092
nucleotide metabolic process GO:0009117 279 0.087
nucleoside triphosphate catabolic process GO:0009143 123 0.087
regulation of nervous system development GO:0051960 264 0.086
limb morphogenesis GO:0035108 4 0.085
purine ribonucleotide metabolic process GO:0009150 227 0.084
cardiac chamber development GO:0003205 1 0.084
organic cyclic compound catabolic process GO:1901361 175 0.081
homeostatic process GO:0042592 331 0.078
neuron differentiation GO:0030182 368 0.077
transcription from rna polymerase ii promoter GO:0006366 252 0.073
aromatic compound catabolic process GO:0019439 168 0.073
negative regulation of cell death GO:0060548 229 0.073
ribonucleotide metabolic process GO:0009259 231 0.072
regulation of nucleic acid templated transcription GO:1903506 380 0.071
nucleoside phosphate metabolic process GO:0006753 283 0.071
cell migration GO:0016477 197 0.071
ribose phosphate metabolic process GO:0019693 235 0.071
purine nucleoside triphosphate catabolic process GO:0009146 122 0.070
purine ribonucleoside metabolic process GO:0046128 168 0.069
ribonucleoside triphosphate metabolic process GO:0009199 141 0.069
purine containing compound metabolic process GO:0072521 253 0.068
regulation of multicellular organismal development GO:2000026 376 0.067
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.065
single organism catabolic process GO:0044712 283 0.065
vasculogenesis GO:0001570 3 0.065
negative regulation of multicellular organismal process GO:0051241 203 0.064
carbohydrate derivative catabolic process GO:1901136 147 0.063
carbohydrate derivative metabolic process GO:1901135 346 0.063
embryonic appendage morphogenesis GO:0035113 4 0.062
positive regulation of rna metabolic process GO:0051254 203 0.061
regulation of apoptotic process GO:0042981 335 0.061
positive regulation of rna biosynthetic process GO:1902680 197 0.060
cellular component biogenesis GO:0044085 368 0.060
organophosphate catabolic process GO:0046434 148 0.059
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.059
glycosyl compound catabolic process GO:1901658 126 0.059
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.058
purine nucleoside triphosphate metabolic process GO:0009144 141 0.057
positive regulation of nucleic acid templated transcription GO:1903508 197 0.056
protein dna complex disassembly GO:0032986 1 0.056
protein complex subunit organization GO:0071822 302 0.055
cellular nitrogen compound catabolic process GO:0044270 163 0.055
embryonic hindlimb morphogenesis GO:0035116 2 0.054
positive regulation of gene expression GO:0010628 244 0.054
heterocycle catabolic process GO:0046700 167 0.053
chromatin assembly or disassembly GO:0006333 1 0.053
positive regulation of transcription dna templated GO:0045893 197 0.053
cellular carbohydrate metabolic process GO:0044262 72 0.052
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.052
single organism organelle organization GO:1902589 180 0.052
cellular component assembly GO:0022607 360 0.052
regulation of rna biosynthetic process GO:2001141 381 0.051
negative regulation of metabolic process GO:0009892 331 0.051
negative regulation of neurogenesis GO:0050768 78 0.050
catabolic process GO:0009056 351 0.049
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.049
organophosphate metabolic process GO:0019637 370 0.048
negative regulation of biosynthetic process GO:0009890 168 0.048
positive regulation of multicellular organismal process GO:0051240 387 0.047
negative regulation of gene expression GO:0010629 199 0.047
purine nucleoside catabolic process GO:0006152 124 0.046
glycosyl compound metabolic process GO:1901657 182 0.046
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.046
nucleotide catabolic process GO:0009166 139 0.045
positive regulation of cellular biosynthetic process GO:0031328 295 0.045
negative regulation of rna metabolic process GO:0051253 123 0.044
single organism carbohydrate catabolic process GO:0044724 40 0.044
macromolecular complex subunit organization GO:0043933 339 0.043
regulation of programmed cell death GO:0043067 341 0.043
gastrulation GO:0007369 2 0.043
organonitrogen compound catabolic process GO:1901565 179 0.043
cell fate determination GO:0001709 2 0.043
chromosome segregation GO:0007059 2 0.043
response to other organism GO:0051707 220 0.042
regulation of neurogenesis GO:0050767 247 0.042
regulation of cell development GO:0060284 263 0.042
negative regulation of nervous system development GO:0051961 79 0.042
cellular homeostasis GO:0019725 252 0.042
skin morphogenesis GO:0043589 2 0.041
positive regulation of neurogenesis GO:0050769 165 0.041
regulation of cell differentiation GO:0045595 320 0.041
purine nucleoside metabolic process GO:0042278 169 0.040
positive regulation of biosynthetic process GO:0009891 319 0.040
appendage morphogenesis GO:0035107 4 0.040
gland development GO:0048732 155 0.039
positive regulation of cell differentiation GO:0045597 217 0.039
negative regulation of macromolecule metabolic process GO:0010605 260 0.039
ribonucleoside metabolic process GO:0009119 174 0.038
positive regulation of developmental process GO:0051094 283 0.038
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.037
anatomical structure morphogenesis GO:0009653 298 0.036
positive regulation of cell proliferation GO:0008284 249 0.036
central nervous system development GO:0007417 311 0.036
ribonucleoside catabolic process GO:0042454 126 0.036
nucleobase containing compound catabolic process GO:0034655 152 0.036
programmed cell death GO:0012501 392 0.036
negative regulation of cellular metabolic process GO:0031324 281 0.036
apoptotic process GO:0006915 381 0.035
cellular response to oxygen containing compound GO:1901701 386 0.035
small molecule catabolic process GO:0044282 59 0.035
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.035
artery development GO:0060840 3 0.035
negative regulation of developmental process GO:0051093 125 0.034
purine nucleoside monophosphate metabolic process GO:0009126 84 0.034
neuron projection development GO:0031175 273 0.034
negative regulation of transcription dna templated GO:0045892 116 0.034
ribonucleotide catabolic process GO:0009261 136 0.034
ribonucleoside triphosphate catabolic process GO:0009203 122 0.034
nucleoside monophosphate catabolic process GO:0009125 56 0.034
regulation of signal transduction GO:0009966 318 0.034
head development GO:0060322 247 0.034
dna methylation on cytosine GO:0032776 3 0.034
macromolecular complex assembly GO:0065003 273 0.033
regulation of phosphate metabolic process GO:0019220 349 0.033
nucleoside monophosphate metabolic process GO:0009123 93 0.032
regulation of gene expression epigenetic GO:0040029 10 0.032
organelle organization GO:0006996 266 0.032
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.032
purine nucleoside monophosphate catabolic process GO:0009128 55 0.032
regulation of cellular component organization GO:0051128 368 0.031
negative regulation of cell communication GO:0010648 158 0.031
muscle structure development GO:0061061 87 0.031
negative regulation of cell development GO:0010721 82 0.030
cellular component morphogenesis GO:0032989 155 0.030
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.029
neuron projection morphogenesis GO:0048812 122 0.029
heart morphogenesis GO:0003007 3 0.029
multicellular organism reproduction GO:0032504 233 0.028
blood vessel development GO:0001568 69 0.028
negative regulation of cell differentiation GO:0045596 99 0.028
positive regulation of signaling GO:0023056 270 0.028
nucleoside metabolic process GO:0009116 179 0.028
cell projection morphogenesis GO:0048858 123 0.028
neuron apoptotic process GO:0051402 88 0.028
intracellular signal transduction GO:0035556 314 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.027
positive regulation of nervous system development GO:0051962 178 0.027
neuron development GO:0048666 286 0.027
multi organism reproductive process GO:0044703 262 0.027
erythrocyte differentiation GO:0030218 1 0.027
regulation of phosphorylation GO:0042325 248 0.026
neurological system process GO:0050877 219 0.026
regulation of cell proliferation GO:0042127 359 0.026
vasculature development GO:0001944 70 0.025
atp catabolic process GO:0006200 54 0.025
lens fiber cell differentiation GO:0070306 3 0.025
embryonic limb morphogenesis GO:0030326 4 0.025
positive regulation of response to stimulus GO:0048584 285 0.025
nucleoside catabolic process GO:0009164 126 0.025
sensory organ development GO:0007423 74 0.025
response to nutrient levels GO:0031667 370 0.025
single organism carbohydrate metabolic process GO:0044723 118 0.024
chromatin disassembly GO:0031498 1 0.024
cell motility GO:0048870 202 0.024
regulation of cell motility GO:2000145 131 0.024
negative regulation of cell proliferation GO:0008285 119 0.023
chemical homeostasis GO:0048878 292 0.023
small gtpase mediated signal transduction GO:0007264 36 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.023
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.023
growth GO:0040007 165 0.022
cellular response to growth factor stimulus GO:0071363 162 0.022
chromatin remodeling GO:0006338 3 0.022
response to extracellular stimulus GO:0009991 380 0.022
regulation of phosphorus metabolic process GO:0051174 349 0.022
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.022
organic hydroxy compound metabolic process GO:1901615 115 0.022
cellular response to endogenous stimulus GO:0071495 377 0.022
cell projection organization GO:0030030 302 0.022
purine ribonucleoside catabolic process GO:0046130 124 0.022
single organism intracellular transport GO:1902582 166 0.022
cell adhesion GO:0007155 110 0.021
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.021
locomotion GO:0040011 237 0.021
anatomical structure formation involved in morphogenesis GO:0048646 83 0.021
sex determination GO:0007530 2 0.021
immune system process GO:0002376 204 0.021
lens development in camera type eye GO:0002088 13 0.021
circulatory system development GO:0072359 134 0.021
ion transmembrane transport GO:0034220 365 0.021
cellular divalent inorganic cation homeostasis GO:0072503 162 0.021
blood vessel morphogenesis GO:0048514 58 0.020
positive regulation of neuron differentiation GO:0045666 126 0.020
neuron fate commitment GO:0048663 4 0.020
localization of cell GO:0051674 202 0.020
ribonucleoside monophosphate catabolic process GO:0009158 55 0.020
ribonucleoside monophosphate metabolic process GO:0009161 88 0.020
chromatin modification GO:0016568 33 0.020
positive regulation of molecular function GO:0044093 230 0.020
positive regulation of signal transduction GO:0009967 175 0.020
negative regulation of cellular biosynthetic process GO:0031327 161 0.019
mechanoreceptor differentiation GO:0042490 2 0.019
dna metabolic process GO:0006259 96 0.019
positive regulation of cell development GO:0010720 176 0.019
cellular response to stress GO:0033554 269 0.019
regulation of neuron differentiation GO:0045664 208 0.019
axonogenesis GO:0007409 71 0.019
response to biotic stimulus GO:0009607 226 0.019
positive regulation of apoptotic process GO:0043065 154 0.019
regulation of locomotion GO:0040012 148 0.019
forebrain development GO:0030900 98 0.019
cellular calcium ion homeostasis GO:0006874 160 0.019
axon development GO:0061564 96 0.019
cellular response to organic cyclic compound GO:0071407 202 0.019
cardiovascular system development GO:0072358 134 0.019
regulation of organ formation GO:0003156 2 0.019
inner ear receptor cell differentiation GO:0060113 2 0.019
negative regulation of response to stimulus GO:0048585 155 0.019
viral transcription GO:0019083 2 0.019
developmental process involved in reproduction GO:0003006 159 0.019
negative regulation of nucleic acid templated transcription GO:1903507 117 0.019
dna methylation or demethylation GO:0044728 8 0.018
regulation of molecular function GO:0065009 398 0.018
tube development GO:0035295 89 0.018
cytosolic calcium ion homeostasis GO:0051480 140 0.018
gliogenesis GO:0042063 93 0.018
motor neuron axon guidance GO:0008045 1 0.018
regulation of stem cell proliferation GO:0072091 14 0.018
negative regulation of programmed cell death GO:0043069 183 0.018
single organism reproductive process GO:0044702 297 0.018
synaptic transmission GO:0007268 235 0.018
neuron projection guidance GO:0097485 24 0.018
regulation of cell fate commitment GO:0010453 1 0.018
reproduction GO:0000003 245 0.018
purine containing compound catabolic process GO:0072523 138 0.017
multicellular organismal signaling GO:0035637 44 0.017
alcohol metabolic process GO:0006066 77 0.017
dna modification GO:0006304 12 0.017
regulation of cell projection organization GO:0031344 175 0.017
tissue development GO:0009888 252 0.017
positive regulation of cell motility GO:2000147 97 0.017
purine nucleotide catabolic process GO:0006195 136 0.016
cellular amine metabolic process GO:0044106 38 0.016
chemotaxis GO:0006935 66 0.016
response to external biotic stimulus GO:0043207 221 0.016
divalent inorganic cation homeostasis GO:0072507 165 0.016
protein complex assembly GO:0006461 263 0.016
cellular response to hormone stimulus GO:0032870 247 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
macromolecule localization GO:0033036 252 0.016
cellular response to external stimulus GO:0071496 118 0.016
membrane organization GO:0061024 94 0.016
gamete generation GO:0007276 124 0.016
protein phosphorylation GO:0006468 345 0.016
negative regulation of cell cycle phase transition GO:1901988 4 0.016
ras protein signal transduction GO:0007265 29 0.016
sexual reproduction GO:0019953 148 0.016
response to oxygen levels GO:0070482 265 0.016
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 3 0.016
regulation of proteasomal protein catabolic process GO:0061136 4 0.016
spermatogenesis GO:0007283 99 0.016
hepaticobiliary system development GO:0061008 90 0.015
cellular catabolic process GO:0044248 295 0.015
stem cell maintenance GO:0019827 6 0.015
secretion GO:0046903 307 0.015
cell morphogenesis involved in differentiation GO:0000904 119 0.015
response to hypoxia GO:0001666 231 0.015
regulation of cellular catabolic process GO:0031329 101 0.015
regulation of mesenchymal cell proliferation GO:0010464 4 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
metal ion homeostasis GO:0055065 186 0.015
cellular response to extracellular stimulus GO:0031668 73 0.015
positive regulation of transport GO:0051050 245 0.014
secretion by cell GO:0032940 248 0.014
dna recombination GO:0006310 3 0.014
positive regulation of cell projection organization GO:0031346 111 0.014
atp dependent chromatin remodeling GO:0043044 1 0.014
positive regulation of phosphate metabolic process GO:0045937 262 0.014
response to carbohydrate GO:0009743 183 0.014
calcium ion homeostasis GO:0055074 162 0.014
regeneration GO:0031099 163 0.014
negative regulation of rna biosynthetic process GO:1902679 118 0.014
positive regulation of neuron projection development GO:0010976 99 0.014
brain development GO:0007420 247 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
carbohydrate catabolic process GO:0016052 40 0.014
vesicle mediated transport GO:0016192 181 0.014
protein complex biogenesis GO:0070271 263 0.014
embryo development GO:0009790 49 0.013
regulation of system process GO:0044057 208 0.013
embryonic pattern specification GO:0009880 1 0.013
taxis GO:0042330 67 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
negative regulation of signal transduction GO:0009968 83 0.013
positive regulation of cell communication GO:0010647 271 0.013
somatic stem cell maintenance GO:0035019 2 0.013
response to wounding GO:0009611 254 0.013
covalent chromatin modification GO:0016569 30 0.013
camera type eye development GO:0043010 48 0.013
hair cell differentiation GO:0035315 2 0.013
ion homeostasis GO:0050801 212 0.013
cell type specific apoptotic process GO:0097285 134 0.013
positive regulation of mapk cascade GO:0043410 92 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
rho protein signal transduction GO:0007266 11 0.013
cell cell signaling GO:0007267 335 0.013
negative regulation of cell cycle g1 s phase transition GO:1902807 2 0.013
regulation of catalytic activity GO:0050790 304 0.013
cellular ion homeostasis GO:0006873 184 0.013
keratinocyte differentiation GO:0030216 2 0.013
epithelium development GO:0060429 96 0.013
heart development GO:0007507 72 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
response to growth factor GO:0070848 189 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
response to nutrient GO:0007584 248 0.012
synaptic growth at neuromuscular junction GO:0051124 1 0.012
establishment of protein localization GO:0045184 141 0.012
regulation of synaptic transmission GO:0050804 141 0.012
chromosome organization GO:0051276 36 0.012
developmental growth GO:0048589 100 0.012
negative regulation of transport GO:0051051 136 0.012
reproductive structure development GO:0048608 128 0.012
sensory perception GO:0007600 101 0.012
sex differentiation GO:0007548 113 0.012
response to bacterium GO:0009617 200 0.012
regulation of response to stress GO:0080134 126 0.012
cellular chemical homeostasis GO:0055082 247 0.012
neuron death GO:0070997 127 0.012
single organism biosynthetic process GO:0044711 342 0.012
male gamete generation GO:0048232 99 0.012
carbohydrate metabolic process GO:0005975 130 0.012
dendrite morphogenesis GO:0048813 43 0.012
amine metabolic process GO:0009308 38 0.012
cation homeostasis GO:0055080 195 0.012
regulation of catabolic process GO:0009894 113 0.012
protein oligomerization GO:0051259 191 0.012
chromatin organization GO:0006325 34 0.012
regulation of neuron death GO:1901214 115 0.012
angiogenesis GO:0001525 53 0.012
cellular cation homeostasis GO:0030003 180 0.011
response to metal ion GO:0010038 253 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
response to glucose GO:0009749 136 0.011
positive regulation of neuron death GO:1901216 43 0.011
erythrocyte homeostasis GO:0034101 2 0.011
multicellular organism growth GO:0035264 1 0.011
histone modification GO:0016570 30 0.011
positive regulation of nucleoside metabolic process GO:0045979 55 0.011
positive regulation of cell death GO:0010942 184 0.011
neuron neuron synaptic transmission GO:0007270 60 0.011
response to alkaloid GO:0043279 132 0.011
regulation of neuron apoptotic process GO:0043523 83 0.011
response to corticosteroid GO:0031960 235 0.011
response to mechanical stimulus GO:0009612 134 0.011
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 2 0.011
regulation of embryonic development GO:0045995 2 0.011
regulation of angiogenesis GO:0045765 39 0.011
cellular response to lipid GO:0071396 201 0.011
positive regulation of cellular component movement GO:0051272 102 0.011
protein localization GO:0008104 191 0.011
regulation of membrane potential GO:0042391 110 0.010
regulation of growth GO:0040008 105 0.010
nucleoside phosphate catabolic process GO:1901292 140 0.010
muscle cell differentiation GO:0042692 52 0.010
regulation of neuron projection development GO:0010975 161 0.010
defense response GO:0006952 194 0.010
morphogenesis of embryonic epithelium GO:0016331 3 0.010
response to acid chemical GO:0001101 222 0.010
nucleoside triphosphate metabolic process GO:0009141 144 0.010
regulation of nucleoside metabolic process GO:0009118 66 0.010
response to hexose GO:0009746 144 0.010

Chd4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.024
disease of anatomical entity DOID:7 0 0.024
musculoskeletal system disease DOID:17 0 0.019
muscle tissue disease DOID:66 0 0.019
muscular disease DOID:0080000 0 0.019