Rattus norvegicus

14 known processes

Chrna10

cholinergic receptor, nicotinic, alpha 10

Chrna10 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neurological system process GO:0050877 219 0.180
Rat
cellular response to endogenous stimulus GO:0071495 377 0.162
response to estrogen GO:0043627 232 0.154
response to estradiol GO:0032355 164 0.125
multi multicellular organism process GO:0044706 138 0.122
positive regulation of multicellular organismal process GO:0051240 387 0.121
single organism reproductive process GO:0044702 297 0.113
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.109
secretion GO:0046903 307 0.105
Rat
central nervous system development GO:0007417 311 0.102
multi organism reproductive process GO:0044703 262 0.102
cellular response to nitrogen compound GO:1901699 210 0.099
regulation of hormone levels GO:0010817 187 0.093
transcription from rna polymerase ii promoter GO:0006366 252 0.090
positive regulation of cell communication GO:0010647 271 0.089
sexual reproduction GO:0019953 148 0.088
cellular response to lipid GO:0071396 201 0.084
lipid metabolic process GO:0006629 283 0.081
positive regulation of signaling GO:0023056 270 0.081
organophosphate metabolic process GO:0019637 370 0.080
positive regulation of cellular biosynthetic process GO:0031328 295 0.078
positive regulation of response to stimulus GO:0048584 285 0.077
response to carbohydrate GO:0009743 183 0.075
regulation of cellular component organization GO:0051128 368 0.074
blood circulation GO:0008015 183 0.070
positive regulation of biosynthetic process GO:0009891 319 0.069
reproductive process GO:0022414 372 0.068
negative regulation of transport GO:0051051 136 0.068
cellular chemical homeostasis GO:0055082 247 0.068
Human
rna metabolic process GO:0016070 406 0.067
positive regulation of cell proliferation GO:0008284 249 0.066
multicellular organismal reproductive process GO:0048609 233 0.064
cellular response to oxygen containing compound GO:1901701 386 0.062
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.061
negative regulation of metabolic process GO:0009892 331 0.059
positive regulation of secretion GO:0051047 140 0.059
Rat
positive regulation of signal transduction GO:0009967 175 0.059
regulation of programmed cell death GO:0043067 341 0.058
protein complex assembly GO:0006461 263 0.056
Rat
response to oxygen levels GO:0070482 265 0.054
single organism biosynthetic process GO:0044711 342 0.054
cellular response to organic cyclic compound GO:0071407 202 0.054
regulation of camp metabolic process GO:0030814 43 0.053
response to lipopolysaccharide GO:0032496 191 0.053
head development GO:0060322 247 0.052
non canonical wnt signaling pathway GO:0035567 3 0.051
positive regulation of developmental process GO:0051094 283 0.050
nucleotide biosynthetic process GO:0009165 98 0.049
positive regulation of mapk cascade GO:0043410 92 0.048
ribose phosphate biosynthetic process GO:0046390 87 0.048
positive regulation of transport GO:0051050 245 0.047
Rat
brain development GO:0007420 247 0.045
protein oligomerization GO:0051259 191 0.044
Rat
telencephalon development GO:0021537 62 0.043
negative regulation of rna metabolic process GO:0051253 123 0.042
transcription dna templated GO:0006351 377 0.042
nucleoside phosphate metabolic process GO:0006753 283 0.042
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.041
feeding behavior GO:0007631 53 0.041
protein complex subunit organization GO:0071822 302 0.040
Rat
reproduction GO:0000003 245 0.040
cellular ion homeostasis GO:0006873 184 0.040
Human
secretion by cell GO:0032940 248 0.040
Rat
cell cell signaling GO:0007267 335 0.039
Rat
programmed cell death GO:0012501 392 0.039
positive regulation of cell differentiation GO:0045597 217 0.039
regulation of protein metabolic process GO:0051246 289 0.038
nucleobase containing small molecule metabolic process GO:0055086 316 0.038
ribonucleotide metabolic process GO:0009259 231 0.037
regulation of phosphorus metabolic process GO:0051174 349 0.037
hormone secretion GO:0046879 115 0.037
positive regulation of rna biosynthetic process GO:1902680 197 0.037
regulation of catalytic activity GO:0050790 304 0.037
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.037
apoptotic process GO:0006915 381 0.036
ion homeostasis GO:0050801 212 0.036
Human
multicellular organism reproduction GO:0032504 233 0.036
developmental process involved in reproduction GO:0003006 159 0.036
peptide secretion GO:0002790 86 0.036
cell activation GO:0001775 97 0.035
organophosphate biosynthetic process GO:0090407 143 0.035
calcium ion homeostasis GO:0055074 162 0.035
Human
positive regulation of cellular protein metabolic process GO:0032270 167 0.035
regulation of hormone secretion GO:0046883 106 0.034
regulation of multicellular organismal development GO:2000026 376 0.033
response to hypoxia GO:0001666 231 0.033
macromolecular complex assembly GO:0065003 273 0.033
Rat
nucleic acid templated transcription GO:0097659 379 0.033
regulation of molecular function GO:0065009 398 0.033
cellular component assembly GO:0022607 360 0.033
Rat
cellular response to peptide GO:1901653 133 0.032
development of primary female sexual characteristics GO:0046545 56 0.032
purine containing compound biosynthetic process GO:0072522 85 0.032
positive regulation of catalytic activity GO:0043085 184 0.032
negative regulation of cellular metabolic process GO:0031324 281 0.032
negative regulation of biosynthetic process GO:0009890 168 0.031
intracellular signal transduction GO:0035556 314 0.031
response to monosaccharide GO:0034284 159 0.031
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.031
macromolecule localization GO:0033036 252 0.031
limb morphogenesis GO:0035108 4 0.031
rna biosynthetic process GO:0032774 380 0.031
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.030
cellular response to peptide hormone stimulus GO:0071375 120 0.030
positive regulation of secretion by cell GO:1903532 128 0.030
Rat
cellular calcium ion homeostasis GO:0006874 160 0.030
Human
gamete generation GO:0007276 124 0.029
monosaccharide metabolic process GO:0005996 61 0.029
regulation of cell proliferation GO:0042127 359 0.029
memory GO:0007613 54 0.029
cellular carbohydrate metabolic process GO:0044262 72 0.029
limbic system development GO:0021761 38 0.029
cellular component biogenesis GO:0044085 368 0.029
Rat
purine nucleotide metabolic process GO:0006163 229 0.028
cyclic nucleotide metabolic process GO:0009187 80 0.028
positive regulation of neurogenesis GO:0050769 165 0.028
synaptic transmission GO:0007268 235 0.028
Rat
cellular response to hormone stimulus GO:0032870 247 0.028
response to peptide hormone GO:0043434 278 0.028
cellular homeostasis GO:0019725 252 0.028
Human
neuron differentiation GO:0030182 368 0.027
positive regulation of gene expression GO:0010628 244 0.027
response to corticosteroid GO:0031960 235 0.027
response to decreased oxygen levels GO:0036293 237 0.026
cyclic nucleotide biosynthetic process GO:0009190 63 0.026
muscle system process GO:0003012 115 0.026
Rat
positive regulation of protein metabolic process GO:0051247 178 0.026
regulation of synaptic transmission GO:0050804 141 0.026
negative regulation of cell death GO:0060548 229 0.026
negative regulation of macromolecule metabolic process GO:0010605 260 0.026
negative regulation of secretion GO:0051048 82 0.026
regulation of intracellular signal transduction GO:1902531 218 0.025
regulation of phosphorylation GO:0042325 248 0.025
cellular response to organonitrogen compound GO:0071417 197 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.025
development of primary sexual characteristics GO:0045137 107 0.025
cellular ketone metabolic process GO:0042180 51 0.024
negative regulation of cellular biosynthetic process GO:0031327 161 0.024
cytosolic calcium ion homeostasis GO:0051480 140 0.024
Human
regulation of nucleic acid templated transcription GO:1903506 380 0.024
regulation of amine transport GO:0051952 54 0.024
Rat
single organism carbohydrate metabolic process GO:0044723 118 0.024
regulation of kinase activity GO:0043549 117 0.023
regulation of phosphate metabolic process GO:0019220 349 0.023
homeostatic process GO:0042592 331 0.023
Human
anatomical structure morphogenesis GO:0009653 298 0.023
tissue development GO:0009888 252 0.023
peptide hormone secretion GO:0030072 84 0.022
positive regulation of intracellular signal transduction GO:1902533 138 0.022
purine ribonucleotide biosynthetic process GO:0009152 81 0.022
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.022
regulation of cell differentiation GO:0045595 320 0.022
hormone metabolic process GO:0042445 69 0.022
purine containing compound metabolic process GO:0072521 253 0.022
ribose phosphate metabolic process GO:0019693 235 0.022
regulation of rna metabolic process GO:0051252 391 0.022
ribonucleotide biosynthetic process GO:0009260 85 0.022
embryonic appendage morphogenesis GO:0035113 4 0.022
regulation of lyase activity GO:0051339 22 0.021
regulation of cellular localization GO:0060341 263 0.021
Rat
regulation of camp biosynthetic process GO:0030817 38 0.021
lung development GO:0030324 43 0.021
alcohol metabolic process GO:0006066 77 0.021
positive regulation of rna metabolic process GO:0051254 203 0.021
oxoacid metabolic process GO:0043436 290 0.021
regulation of nucleotide metabolic process GO:0006140 117 0.021
proteolysis GO:0006508 175 0.021
negative regulation of secretion by cell GO:1903531 72 0.021
response to alkaloid GO:0043279 132 0.021
Rat
stress activated protein kinase signaling cascade GO:0031098 37 0.021
regulation of system process GO:0044057 208 0.020
regulation of anatomical structure morphogenesis GO:0022603 141 0.020
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.020
response to ammonium ion GO:0060359 71 0.020
Rat
response to amino acid GO:0043200 75 0.020
single organism organelle organization GO:1902589 180 0.020
negative regulation of gene expression GO:0010629 199 0.020
regulation of signal transduction GO:0009966 318 0.020
carbohydrate metabolic process GO:0005975 130 0.019
positive regulation of neuron differentiation GO:0045666 126 0.019
phospholipid metabolic process GO:0006644 61 0.019
positive regulation of transcription dna templated GO:0045893 197 0.019
cellular cation homeostasis GO:0030003 180 0.019
Human
divalent inorganic cation homeostasis GO:0072507 165 0.019
Human
regulation of apoptotic process GO:0042981 335 0.019
regulation of secretion GO:0051046 224 0.019
Rat
regulation of cellular protein metabolic process GO:0032268 267 0.019
organic acid metabolic process GO:0006082 292 0.019
positive regulation of cell development GO:0010720 176 0.019
cellular divalent inorganic cation homeostasis GO:0072503 162 0.019
Human
forebrain development GO:0030900 98 0.018
respiratory system development GO:0060541 45 0.018
positive regulation of nervous system development GO:0051962 178 0.018
negative regulation of apoptotic process GO:0043066 181 0.018
circulatory system process GO:0003013 183 0.018
carbohydrate derivative metabolic process GO:1901135 346 0.018
cellular amine metabolic process GO:0044106 38 0.018
regulation of membrane potential GO:0042391 110 0.018
response to molecule of bacterial origin GO:0002237 194 0.018
grooming behavior GO:0007625 4 0.018
positive regulation of molecular function GO:0044093 230 0.018
positive regulation of ion transport GO:0043270 94 0.018
Rat
inorganic cation transmembrane transport GO:0098662 202 0.018
Rat
cell adhesion GO:0007155 110 0.017
cellular response to stress GO:0033554 269 0.017
regulation of blood vessel size GO:0050880 89 0.017
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.017
negative regulation of transcription dna templated GO:0045892 116 0.017
camp metabolic process GO:0046058 63 0.017
positive regulation of protein modification process GO:0031401 142 0.017
metal ion transport GO:0030001 289 0.017
Rat
carboxylic acid metabolic process GO:0019752 289 0.017
protein phosphorylation GO:0006468 345 0.017
response to acid chemical GO:0001101 222 0.017
response to hexose GO:0009746 144 0.017
negative regulation of programmed cell death GO:0043069 183 0.016
neuron projection development GO:0031175 273 0.016
positive regulation of cell projection organization GO:0031346 111 0.016
progesterone biosynthetic process GO:0006701 3 0.016
muscle contraction GO:0006936 88 0.016
Rat
cation transmembrane transport GO:0098655 263 0.016
glucose homeostasis GO:0042593 75 0.016
female sex differentiation GO:0046660 59 0.016
response to transition metal nanoparticle GO:1990267 122 0.016
metal ion homeostasis GO:0055065 186 0.016
Human
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.016
Human
cell projection morphogenesis GO:0048858 123 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
embryonic limb morphogenesis GO:0030326 4 0.016
appendage morphogenesis GO:0035107 4 0.016
protein localization GO:0008104 191 0.016
carboxylic acid transport GO:0046942 115 0.016
epithelial cell proliferation GO:0050673 54 0.015
fractalkine metabolic process GO:0050756 3 0.015
female gonad development GO:0008585 53 0.015
female pregnancy GO:0007565 122 0.015
cyclic purine nucleotide metabolic process GO:0052652 62 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.015
regulation of cellular component movement GO:0051270 150 0.015
response to metal ion GO:0010038 253 0.015
camp biosynthetic process GO:0006171 47 0.015
regulation of cell development GO:0060284 263 0.015
positive regulation of calcium ion transport GO:0051928 36 0.015
regulation of catecholamine secretion GO:0050433 32 0.015
Rat
regulation of peptide transport GO:0090087 87 0.015
chemical homeostasis GO:0048878 292 0.015
Human
cellular lipid metabolic process GO:0044255 208 0.015
positive regulation of stress activated protein kinase signaling cascade GO:0070304 17 0.015
positive regulation of apoptotic process GO:0043065 154 0.015
purine nucleotide biosynthetic process GO:0006164 83 0.015
regulation of blood pressure GO:0008217 83 0.015
response to cytokine GO:0034097 215 0.015
rhythmic process GO:0048511 156 0.015
peptide transport GO:0015833 97 0.015
positive regulation of cyclase activity GO:0031281 15 0.014
respiratory tube development GO:0030323 43 0.014
protein complex biogenesis GO:0070271 263 0.014
Rat
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
sensory perception GO:0007600 101 0.014
Rat
nucleotide metabolic process GO:0009117 279 0.014
regulation of body fluid levels GO:0050878 90 0.014
cellular response to alcohol GO:0097306 87 0.014
cellular response to metal ion GO:0071248 55 0.014
tube development GO:0035295 89 0.014
regulation of protein transport GO:0051223 68 0.014
establishment of planar polarity GO:0001736 1 0.014
response to temperature stimulus GO:0009266 94 0.014
nucleoside phosphate biosynthetic process GO:1901293 102 0.014
regulation of transcription dna templated GO:0006355 374 0.014
regulation of mapk cascade GO:0043408 116 0.014
regulation of cellular component size GO:0032535 51 0.014
catecholamine secretion GO:0050432 33 0.014
Rat
negative regulation of rna biosynthetic process GO:1902679 118 0.014
transmembrane transport GO:0055085 412 0.014
response to radiation GO:0009314 137 0.014
divalent metal ion transport GO:0070838 132 0.014
regulation of cell projection organization GO:0031344 175 0.014
regulation of establishment of planar polarity GO:0090175 2 0.014
regulation of anatomical structure size GO:0090066 135 0.013
circadian rhythm GO:0007623 88 0.013
response to cocaine GO:0042220 39 0.013
Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.013
cation transport GO:0006812 382 0.013
regulation of nucleotide biosynthetic process GO:0030808 47 0.013
sex differentiation GO:0007548 113 0.013
positive regulation of saliva secretion GO:0046878 3 0.013
insulin secretion GO:0030073 69 0.013
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.013
steroid metabolic process GO:0008202 73 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.013
regulation of protein modification process GO:0031399 194 0.013
sensory perception of bitter taste GO:0050913 4 0.013
positive regulation of protein kinase activity GO:0045860 73 0.013
behavior GO:0007610 205 0.013
regulation of behavior GO:0050795 61 0.013
neuromuscular synaptic transmission GO:0007274 2 0.013
mesoderm development GO:0007498 2 0.013
regulation of phosphatidylinositol dephosphorylation GO:0060304 1 0.013
response to other organism GO:0051707 220 0.012
positive regulation of growth GO:0045927 55 0.012
vascular process in circulatory system GO:0003018 96 0.012
response to inorganic substance GO:0010035 377 0.012
Rat
mapk cascade GO:0000165 140 0.012
cell projection organization GO:0030030 302 0.012
macromolecular complex subunit organization GO:0043933 339 0.012
Rat
camera type eye development GO:0043010 48 0.012
divalent inorganic cation transport GO:0072511 134 0.012
aging GO:0007568 241 0.012
intracellular transport GO:0046907 185 0.012
regulation of excretion GO:0044062 21 0.012
localization of cell GO:0051674 202 0.012
response to biotic stimulus GO:0009607 226 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 39 0.012
response to glucocorticoid GO:0051384 223 0.012
single organism carbohydrate catabolic process GO:0044724 40 0.012
smooth muscle contraction GO:0006939 37 0.012
regulation of vasoconstriction GO:0019229 44 0.012
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.011
negative regulation of phosphate metabolic process GO:0045936 80 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
defense response GO:0006952 194 0.011
regulation of rna biosynthetic process GO:2001141 381 0.011
cellular response to inorganic substance GO:0071241 65 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
protein maturation GO:0051604 68 0.011
regulation of protein kinase activity GO:0045859 105 0.011
regulation of neuron death GO:1901214 115 0.011
positive regulation of phosphorus metabolic process GO:0010562 262 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
pallium development GO:0021543 42 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
regulation of locomotion GO:0040012 148 0.011
reproductive structure development GO:0048608 128 0.011
regulation of secretion by cell GO:1903530 208 0.011
Rat
response to external biotic stimulus GO:0043207 221 0.011
hexose metabolic process GO:0019318 58 0.011
regulation of tube size GO:0035150 89 0.011
glucose metabolic process GO:0006006 52 0.011
male gamete generation GO:0048232 99 0.011
organic substance catabolic process GO:1901575 316 0.011
cellular response to growth factor stimulus GO:0071363 162 0.011
Rat
negative regulation of signaling GO:0023057 157 0.011
growth GO:0040007 165 0.011
signal release GO:0023061 145 0.011
regulation of muscle contraction GO:0006937 53 0.011
response to vitamin GO:0033273 131 0.011
cellular response to acid chemical GO:0071229 75 0.011
heart contraction GO:0060047 57 0.011
dephosphorylation GO:0016311 98 0.011
muscle cell proliferation GO:0033002 84 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
Rat
urogenital system development GO:0001655 78 0.011
immune response GO:0006955 104 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
response to nutrient GO:0007584 248 0.011
amide transport GO:0042886 105 0.011
single organism intracellular transport GO:1902582 166 0.011
negative regulation of hormone secretion GO:0046888 46 0.011
maintenance of location GO:0051235 17 0.011
cellular response to carbohydrate stimulus GO:0071322 72 0.011
chromosome segregation GO:0007059 2 0.011
heart process GO:0003015 57 0.011
positive regulation of map kinase activity GO:0043406 46 0.010
response to glucose GO:0009749 136 0.010
regulation of cell growth GO:0001558 85 0.010
locomotion GO:0040011 237 0.010
gonad development GO:0008406 104 0.010
action potential GO:0001508 54 0.010
neuron apoptotic process GO:0051402 88 0.010
regulation of transferase activity GO:0051338 123 0.010
response to electrical stimulus GO:0051602 56 0.010
spermatogenesis GO:0007283 99 0.010
cellular metal ion homeostasis GO:0006875 172 0.010
Human
indole containing compound metabolic process GO:0042430 11 0.010
regulation of muscle system process GO:0090257 79 0.010
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.010
regulation of insulin secretion GO:0050796 65 0.010
chemokine metabolic process GO:0050755 3 0.010
response to nutrient levels GO:0031667 370 0.010
amine metabolic process GO:0009308 38 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
hair cell differentiation GO:0035315 2 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
male gonad development GO:0008584 59 0.010

Chrna10 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
congenital adrenal hyperplasia DOID:0050811 0 0.021
disease of metabolism DOID:0014667 0 0.021
lipid metabolism disorder DOID:3146 0 0.021
inherited metabolic disorder DOID:655 0 0.021
steroid inherited metabolic disorder DOID:1701 0 0.021
disease of anatomical entity DOID:7 0 0.014
urinary system disease DOID:18 0 0.014
nervous system disease DOID:863 0 0.012