Rattus norvegicus

65 known processes

Chrna4

cholinergic receptor, nicotinic, alpha 4

(Aliases: NARAC)

Chrna4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to alkaloid GO:0043279 132 0.612
Human Mouse Rat
phasic smooth muscle contraction GO:0014821 3 0.506
locomotion GO:0040011 237 0.490
Worm
neurological system process GO:0050877 219 0.434
Human Mouse Rat
cell cell signaling GO:0007267 335 0.426
single organism reproductive process GO:0044702 297 0.409
organelle organization GO:0006996 266 0.370
purine containing compound metabolic process GO:0072521 253 0.356
carbohydrate derivative metabolic process GO:1901135 346 0.346
ribonucleotide metabolic process GO:0009259 231 0.333
neuron development GO:0048666 286 0.313
secretion by cell GO:0032940 248 0.282
regulation of purine nucleotide metabolic process GO:1900542 115 0.268
heart morphogenesis GO:0003007 3 0.262
nucleobase containing small molecule metabolic process GO:0055086 316 0.258
actin filament based process GO:0030029 86 0.256
somatostatin receptor signaling pathway GO:0038169 4 0.246
synaptic transmission GO:0007268 235 0.243
cytoskeleton organization GO:0007010 111 0.236
nucleic acid templated transcription GO:0097659 379 0.236
positive regulation of secretion GO:0051047 140 0.235
cellular component biogenesis GO:0044085 368 0.234
ribose phosphate metabolic process GO:0019693 235 0.229
protein complex subunit organization GO:0071822 302 0.220
purine nucleotide metabolic process GO:0006163 229 0.211
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.201
regulation of secretion GO:0051046 224 0.189
brain development GO:0007420 247 0.182
regulation of secretion by cell GO:1903530 208 0.177
peristalsis GO:0030432 2 0.176
head development GO:0060322 247 0.175
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.173
ribose phosphate biosynthetic process GO:0046390 87 0.171
inorganic cation transmembrane transport GO:0098662 202 0.170
Rat
cation transport GO:0006812 382 0.164
cellular response to hormone stimulus GO:0032870 247 0.164
macromolecular complex subunit organization GO:0043933 339 0.161
regulation of transcription dna templated GO:0006355 374 0.160
signal release GO:0023061 145 0.159
regulation of cell development GO:0060284 263 0.158
actin cytoskeleton organization GO:0030036 73 0.155
regulation of cellular localization GO:0060341 263 0.154
adenylate cyclase inhibiting opioid receptor signaling pathway GO:0031635 2 0.154
organonitrogen compound biosynthetic process GO:1901566 167 0.153
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.148
cell projection morphogenesis GO:0048858 123 0.146
nucleotide metabolic process GO:0009117 279 0.141
neuron projection development GO:0031175 273 0.140
positive regulation of transport GO:0051050 245 0.139
negative regulation of cyclic nucleotide metabolic process GO:0030800 15 0.137
positive regulation of molecular function GO:0044093 230 0.137
cellular component assembly GO:0022607 360 0.136
single organism organelle organization GO:1902589 180 0.134
rna biosynthetic process GO:0032774 380 0.132
divalent inorganic cation transport GO:0072511 134 0.130
Mouse
secretion GO:0046903 307 0.130
purine nucleotide biosynthetic process GO:0006164 83 0.127
multicellular organismal movement GO:0050879 17 0.124
Rat
vesicle mediated transport GO:0016192 181 0.124
cell morphogenesis involved in differentiation GO:0000904 119 0.124
transcription dna templated GO:0006351 377 0.124
nucleoside phosphate metabolic process GO:0006753 283 0.123
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.122
cellular component movement GO:0006928 248 0.121
regulation of nucleotide metabolic process GO:0006140 117 0.120
purine ribonucleotide metabolic process GO:0009150 227 0.116
regulation of phosphate metabolic process GO:0019220 349 0.115
regulation of membrane potential GO:0042391 110 0.115
Mouse
cellular response to stress GO:0033554 269 0.115
Human
negative regulation of signaling GO:0023057 157 0.114
motor neuron axon guidance GO:0008045 1 0.113
organic hydroxy compound metabolic process GO:1901615 115 0.112
negative regulation of cellular biosynthetic process GO:0031327 161 0.111
regulation of multicellular organismal development GO:2000026 376 0.110
cation transmembrane transport GO:0098655 263 0.110
purine containing compound biosynthetic process GO:0072522 85 0.109
transcription from rna polymerase ii promoter GO:0006366 252 0.107
defecation GO:0030421 1 0.107
neuropeptide signaling pathway GO:0007218 29 0.107
central nervous system development GO:0007417 311 0.106
cyclic nucleotide metabolic process GO:0009187 80 0.105
regulation of signal transduction GO:0009966 318 0.103
neuron differentiation GO:0030182 368 0.102
purine ribonucleotide biosynthetic process GO:0009152 81 0.102
regulation of nucleic acid templated transcription GO:1903506 380 0.102
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.102
catabolic process GO:0009056 351 0.101
regulation of nervous system development GO:0051960 264 0.100
ribonucleoside metabolic process GO:0009119 174 0.099
reproductive process GO:0022414 372 0.099
Worm
regulation of intracellular signal transduction GO:1902531 218 0.094
dendrite development GO:0016358 72 0.094
regulation of cellular component organization GO:0051128 368 0.093
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.093
organophosphate metabolic process GO:0019637 370 0.091
growth GO:0040007 165 0.089
mapk cascade GO:0000165 140 0.089
chemical homeostasis GO:0048878 292 0.088
negative regulation of cell proliferation GO:0008285 119 0.087
organonitrogen compound catabolic process GO:1901565 179 0.087
intracellular signal transduction GO:0035556 314 0.087
purine nucleoside triphosphate catabolic process GO:0009146 122 0.086
aromatic compound catabolic process GO:0019439 168 0.085
cellular lipid metabolic process GO:0044255 208 0.085
positive regulation of synaptic transmission GO:0050806 62 0.084
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.083
inorganic ion transmembrane transport GO:0098660 229 0.083
Rat
cardiovascular system development GO:0072358 134 0.083
Rat
axonogenesis GO:0007409 71 0.080
hormone secretion GO:0046879 115 0.079
regulation of neurogenesis GO:0050767 247 0.076
nitrogen compound transport GO:0071705 229 0.075
negative regulation of lyase activity GO:0051350 8 0.074
regulation of rna biosynthetic process GO:2001141 381 0.074
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.074
positive regulation of gene expression GO:0010628 244 0.074
cellular response to endogenous stimulus GO:0071495 377 0.073
cell projection organization GO:0030030 302 0.073
ribonucleotide biosynthetic process GO:0009260 85 0.073
actin filament bundle organization GO:0061572 19 0.072
multi organism reproductive process GO:0044703 262 0.072
Worm
transmembrane transport GO:0055085 412 0.070
negative regulation of biosynthetic process GO:0009890 168 0.070
somatostatin signaling pathway GO:0038170 4 0.069
positive regulation of response to food GO:0032097 3 0.069
regulation of adenylate cyclase activity GO:0045761 18 0.069
macromolecule localization GO:0033036 252 0.069
glycosyl compound metabolic process GO:1901657 182 0.068
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.067
membrane organization GO:0061024 94 0.067
positive regulation of phosphorus metabolic process GO:0010562 262 0.066
regulation of cellular catabolic process GO:0031329 101 0.066
learning or memory GO:0007611 90 0.065
cellular component morphogenesis GO:0032989 155 0.065
response to cocaine GO:0042220 39 0.065
Rat
regulation of camp metabolic process GO:0030814 43 0.064
response to extracellular stimulus GO:0009991 380 0.064
purine ribonucleotide catabolic process GO:0009154 136 0.064
ribonucleoside catabolic process GO:0042454 126 0.063
organic substance catabolic process GO:1901575 316 0.063
multicellular organism reproduction GO:0032504 233 0.063
Worm
nucleoside triphosphate metabolic process GO:0009141 144 0.062
negative regulation of nucleotide metabolic process GO:0045980 23 0.062
synaptic transmission cholinergic GO:0007271 11 0.062
regulation of nucleotide biosynthetic process GO:0030808 47 0.061
regulation of catalytic activity GO:0050790 304 0.061
negative regulation of multicellular organismal process GO:0051241 203 0.061
protein complex biogenesis GO:0070271 263 0.061
regulation of peptide hormone secretion GO:0090276 80 0.061
regulation of rna metabolic process GO:0051252 391 0.060
g protein coupled receptor signaling pathway GO:0007186 242 0.059
Rat
positive regulation of cell differentiation GO:0045597 217 0.058
carbohydrate derivative catabolic process GO:1901136 147 0.058
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 24 0.058
response to food GO:0032094 27 0.058
dendrite morphogenesis GO:0048813 43 0.058
regulation of molecular function GO:0065009 398 0.058
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.057
negative regulation of cell communication GO:0010648 158 0.057
response to nutrient levels GO:0031667 370 0.057
nucleoside metabolic process GO:0009116 179 0.057
muscle contraction GO:0006936 88 0.056
Rat
lipid metabolic process GO:0006629 283 0.056
neuromuscular synaptic transmission GO:0007274 2 0.055
Worm
multicellular organismal reproductive process GO:0048609 233 0.055
Worm
nucleotide biosynthetic process GO:0009165 98 0.055
blood circulation GO:0008015 183 0.055
negative regulation of phosphorus metabolic process GO:0010563 80 0.055
ribonucleoside triphosphate catabolic process GO:0009203 122 0.055
regulation of neuron differentiation GO:0045664 208 0.054
positive regulation of transcription dna templated GO:0045893 197 0.054
nucleoside phosphate catabolic process GO:1901292 140 0.054
negative regulation of neuron differentiation GO:0045665 62 0.053
regulation of g protein coupled receptor protein signaling pathway GO:0008277 28 0.053
carbohydrate derivative biosynthetic process GO:1901137 124 0.053
organophosphate biosynthetic process GO:0090407 143 0.052
cellular nitrogen compound catabolic process GO:0044270 163 0.052
anatomical structure morphogenesis GO:0009653 298 0.051
rna metabolic process GO:0016070 406 0.051
circulatory system process GO:0003013 183 0.051
positive regulation of cell development GO:0010720 176 0.051
negative regulation of molecular function GO:0044092 133 0.050
cellular protein localization GO:0034613 122 0.050
heart development GO:0007507 72 0.050
Rat
heterocycle catabolic process GO:0046700 167 0.050
regulation of camp biosynthetic process GO:0030817 38 0.049
purine nucleoside metabolic process GO:0042278 169 0.049
cellular amino acid metabolic process GO:0006520 107 0.049
purine nucleotide catabolic process GO:0006195 136 0.049
negative regulation of metabolic process GO:0009892 331 0.049
regulation of neuron projection development GO:0010975 161 0.048
muscle system process GO:0003012 115 0.048
Rat
cardiac ventricle development GO:0003231 1 0.048
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.048
cell part morphogenesis GO:0032990 123 0.048
thyroid gland development GO:0030878 1 0.048
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.048
positive regulation of multicellular organismal process GO:0051240 387 0.047
negative regulation of cellular metabolic process GO:0031324 281 0.047
localization of cell GO:0051674 202 0.047
potassium ion transmembrane transport GO:0071805 71 0.047
Rat
behavior GO:0007610 205 0.047
Human Mouse Worm
regulation of cell differentiation GO:0045595 320 0.046
positive regulation of phosphate metabolic process GO:0045937 262 0.046
anterior posterior pattern specification GO:0009952 1 0.046
cyclic purine nucleotide metabolic process GO:0052652 62 0.046
purine nucleoside triphosphate metabolic process GO:0009144 141 0.046
camp metabolic process GO:0046058 63 0.046
response to nutrient GO:0007584 248 0.045
regulation of actin cytoskeleton organization GO:0032956 30 0.045
regulation of response to food GO:0032095 11 0.045
cellular macromolecule localization GO:0070727 122 0.045
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.045
saliva secretion GO:0046541 3 0.045
positive regulation of hydrolase activity GO:0051345 86 0.045
cellular amine metabolic process GO:0044106 38 0.044
exocytosis GO:0006887 60 0.044
sensory perception GO:0007600 101 0.044
Mouse Rat
negative regulation of camp metabolic process GO:0030815 14 0.044
negative regulation of response to stimulus GO:0048585 155 0.044
wound healing GO:0042060 122 0.044
nucleoside phosphate biosynthetic process GO:1901293 102 0.044
calcium ion transmembrane transport GO:0070588 70 0.044
regulation of cellular component biogenesis GO:0044087 86 0.043
positive regulation of nucleic acid templated transcription GO:1903508 197 0.043
nucleoside catabolic process GO:0009164 126 0.043
negative regulation of purine nucleotide metabolic process GO:1900543 23 0.043
regulation of phosphorus metabolic process GO:0051174 349 0.043
single organism cellular localization GO:1902580 102 0.042
response to ethanol GO:0045471 162 0.042
Rat
forebrain development GO:0030900 98 0.042
single organism catabolic process GO:0044712 283 0.042
regulation of behavior GO:0050795 61 0.042
Worm
organic cyclic compound catabolic process GO:1901361 175 0.041
organic acid metabolic process GO:0006082 292 0.041
negative regulation of cell differentiation GO:0045596 99 0.041
single organism biosynthetic process GO:0044711 342 0.040
cellular response to oxygen containing compound GO:1901701 386 0.040
establishment of vesicle localization GO:0051650 31 0.040
positive regulation of catalytic activity GO:0043085 184 0.040
regulation of phosphorylation GO:0042325 248 0.040
regulation of actin filament bundle assembly GO:0032231 13 0.040
negative regulation of camp biosynthetic process GO:0030818 12 0.040
metal ion transport GO:0030001 289 0.039
Mouse Rat
actin filament organization GO:0007015 42 0.039
response to ketone GO:1901654 182 0.039
positive regulation of secretion by cell GO:1903532 128 0.039
positive regulation of developmental process GO:0051094 283 0.039
regulation of purine nucleotide catabolic process GO:0033121 65 0.038
urinary bladder smooth muscle contraction GO:0014832 4 0.038
limbic system development GO:0021761 38 0.038
nucleotide catabolic process GO:0009166 139 0.038
response to estrogen GO:0043627 232 0.038
action potential GO:0001508 54 0.038
Mouse
mesoderm development GO:0007498 2 0.038
regulation of hormone levels GO:0010817 187 0.038
regulation of muscle contraction GO:0006937 53 0.037
positive regulation of signaling GO:0023056 270 0.037
negative regulation of phosphate metabolic process GO:0045936 80 0.036
response to calcium ion GO:0051592 59 0.036
glutamate receptor signaling pathway GO:0007215 43 0.036
ion transmembrane transport GO:0034220 365 0.036
regulation of protein metabolic process GO:0051246 289 0.036
glycosyl compound catabolic process GO:1901658 126 0.036
detection of visible light GO:0009584 3 0.036
embryonic pattern specification GO:0009880 1 0.036
positive regulation of hormone secretion GO:0046887 65 0.036
negative regulation of rna biosynthetic process GO:1902679 118 0.036
organic anion transport GO:0015711 132 0.035
neuron projection morphogenesis GO:0048812 122 0.035
peptide hormone secretion GO:0030072 84 0.035
positive regulation of nervous system development GO:0051962 178 0.035
potassium ion transport GO:0006813 97 0.035
Rat
cellular response to growth factor stimulus GO:0071363 162 0.035
Rat
positive regulation of neurogenesis GO:0050769 165 0.034
response to ammonium ion GO:0060359 71 0.034
Rat
cellular homeostasis GO:0019725 252 0.034
axon development GO:0061564 96 0.034
positive regulation of signal transduction GO:0009967 175 0.034
regulation of protein modification process GO:0031399 194 0.034
regulation of hydrolase activity GO:0051336 143 0.033
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 15 0.033
sexual reproduction GO:0019953 148 0.033
hormone transport GO:0009914 121 0.033
response to inorganic substance GO:0010035 377 0.033
Rat
ribonucleoside triphosphate metabolic process GO:0009199 141 0.033
excretion GO:0007588 24 0.032
actin filament bundle assembly GO:0051017 19 0.032
purine containing compound catabolic process GO:0072523 138 0.032
negative regulation of cyclase activity GO:0031280 7 0.032
positive regulation of cellular component biogenesis GO:0044089 55 0.032
response to wounding GO:0009611 254 0.032
cell type specific apoptotic process GO:0097285 134 0.032
regulation of actin filament based process GO:0032970 42 0.032
negative regulation of transcription dna templated GO:0045892 116 0.031
oxoacid metabolic process GO:0043436 290 0.031
cellular response to nitrogen compound GO:1901699 210 0.031
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.031
regulation of neuron apoptotic process GO:0043523 83 0.031
regulation of blood pressure GO:0008217 83 0.030
regulation of protein phosphorylation GO:0001932 183 0.030
purine ribonucleoside metabolic process GO:0046128 168 0.030
positive regulation of cellular component organization GO:0051130 200 0.030
circulatory system development GO:0072359 134 0.030
Rat
neurotransmitter secretion GO:0007269 33 0.030
ion homeostasis GO:0050801 212 0.029
positive regulation of cytoskeleton organization GO:0051495 26 0.029
cyclic nucleotide biosynthetic process GO:0009190 63 0.029
axon guidance GO:0007411 24 0.029
single organism intracellular transport GO:1902582 166 0.029
smooth muscle contraction GO:0006939 37 0.029
phototransduction visible light GO:0007603 2 0.028
regulation of cellular protein metabolic process GO:0032268 267 0.028
negative regulation of macromolecule metabolic process GO:0010605 260 0.028
regulation of the force of heart contraction by chemical signal GO:0003057 2 0.028
positive regulation of rna metabolic process GO:0051254 203 0.028
establishment of organelle localization GO:0051656 37 0.028
ribonucleotide catabolic process GO:0009261 136 0.028
cell motility GO:0048870 202 0.028
synaptic vesicle localization GO:0097479 24 0.028
nucleobase containing compound catabolic process GO:0034655 152 0.028
tissue development GO:0009888 252 0.028
regulation of nucleoside metabolic process GO:0009118 66 0.028
neuron projection guidance GO:0097485 24 0.028
positive regulation of protein metabolic process GO:0051247 178 0.027
reproduction GO:0000003 245 0.027
Worm
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.027
regulation of synaptic transmission GO:0050804 141 0.027
negative regulation of neurogenesis GO:0050768 78 0.027
synaptic transmission gabaergic GO:0051932 22 0.027
negative regulation of purine nucleotide biosynthetic process GO:1900372 12 0.027
positive regulation of neuron differentiation GO:0045666 126 0.027
hormone mediated signaling pathway GO:0009755 23 0.027
amine metabolic process GO:0009308 38 0.027
regulation of system process GO:0044057 208 0.027
cellular ion homeostasis GO:0006873 184 0.027
cellular potassium ion transport GO:0071804 72 0.026
Rat
small gtpase mediated signal transduction GO:0007264 36 0.026
regulation of cyclase activity GO:0031279 21 0.026
response to metal ion GO:0010038 253 0.026
negative regulation of nervous system development GO:0051961 79 0.026
purine ribonucleoside catabolic process GO:0046130 124 0.026
multi multicellular organism process GO:0044706 138 0.026
Worm
positive regulation of heart contraction GO:0045823 15 0.026
cation homeostasis GO:0055080 195 0.026
ribonucleoside monophosphate metabolic process GO:0009161 88 0.025
apoptotic process GO:0006915 381 0.025
regulation of cell projection organization GO:0031344 175 0.025
regulation of organelle organization GO:0033043 80 0.025
positive regulation of nucleoside metabolic process GO:0045979 55 0.025
regulation of programmed cell death GO:0043067 341 0.025
regulation of cellular amine metabolic process GO:0033238 8 0.025
organic acid transport GO:0015849 116 0.025
cell migration GO:0016477 197 0.025
regulation of blood circulation GO:1903522 110 0.025
sensory organ development GO:0007423 74 0.025
camera type eye development GO:0043010 48 0.025
cellular divalent inorganic cation homeostasis GO:0072503 162 0.025
peptide secretion GO:0002790 86 0.024
urinary tract smooth muscle contraction GO:0014848 4 0.024
regulation of mapk cascade GO:0043408 116 0.024
negative regulation of catalytic activity GO:0043086 103 0.024
positive regulation of biosynthetic process GO:0009891 319 0.024
male sex differentiation GO:0046661 64 0.024
response to insulin GO:0032868 133 0.024
negative regulation of apoptotic process GO:0043066 181 0.024
gtp metabolic process GO:0046039 72 0.024
regulation of erk1 and erk2 cascade GO:0070372 41 0.024
positive regulation of rna biosynthetic process GO:1902680 197 0.024
ras protein signal transduction GO:0007265 29 0.024
learning GO:0007612 33 0.024
cell morphogenesis GO:0000902 142 0.024
associative learning GO:0008306 19 0.023
positive regulation of response to extracellular stimulus GO:0032106 3 0.023
purine nucleoside catabolic process GO:0006152 124 0.023
regulation of lyase activity GO:0051339 22 0.023
regulation of catabolic process GO:0009894 113 0.023
neurotransmitter transport GO:0006836 42 0.023
negative regulation of calcium ion import GO:0090281 2 0.023
micturition GO:0060073 4 0.023
phenol containing compound metabolic process GO:0018958 30 0.023
positive regulation of cell communication GO:0010647 271 0.023
establishment of synaptic vesicle localization GO:0097480 23 0.023
cellular calcium ion homeostasis GO:0006874 160 0.023
protein phosphorylation GO:0006468 345 0.023
negative regulation of adenylate cyclase activity GO:0007194 7 0.023
regulation of excitatory postsynaptic membrane potential GO:0060079 18 0.023
regulation of insulin secretion GO:0050796 65 0.023
regulation of protein kinase activity GO:0045859 105 0.023
organelle localization GO:0051640 55 0.023
negative regulation of cell death GO:0060548 229 0.023
regulation of saliva secretion GO:0046877 3 0.022
regulation of developmental growth GO:0048638 45 0.022
regulation of ion transmembrane transport GO:0034765 121 0.022
Rat
cellular chemical homeostasis GO:0055082 247 0.022
metal ion homeostasis GO:0055065 186 0.022
regulation of defecation GO:2000292 1 0.022
carbohydrate homeostasis GO:0033500 75 0.022
negative regulation of follicle stimulating hormone secretion GO:0046882 3 0.022
organophosphate catabolic process GO:0046434 148 0.022
desensitization of g protein coupled receptor protein signaling pathway GO:0002029 10 0.022
regulation of neurotransmitter levels GO:0001505 42 0.021
programmed cell death GO:0012501 392 0.021
negative regulation of secretion by cell GO:1903531 72 0.021
alcohol metabolic process GO:0006066 77 0.021
negative regulation of signal transduction GO:0009968 83 0.021
response to acid chemical GO:0001101 222 0.021
regulation of body fluid levels GO:0050878 90 0.021
regulation of transferase activity GO:0051338 123 0.021
cellular cation homeostasis GO:0030003 180 0.021
regulation of hormone secretion GO:0046883 106 0.021
single organism membrane organization GO:0044802 74 0.021
signal transduction by phosphorylation GO:0023014 144 0.021
positive regulation of nucleotide catabolic process GO:0030813 53 0.021
detection of external stimulus GO:0009581 13 0.021
regulation of transmembrane transporter activity GO:0022898 49 0.020
cellular catabolic process GO:0044248 295 0.020
regulation of systemic arterial blood pressure GO:0003073 30 0.020
activation of protein kinase activity GO:0032147 47 0.020
negative regulation of cyclic nucleotide biosynthetic process GO:0030803 12 0.020
reproductive structure development GO:0048608 128 0.020
brain renin angiotensin system GO:0002035 3 0.020
single organism behavior GO:0044708 130 0.020
Human Mouse
positive regulation of protein kinase activity GO:0045860 73 0.020
macromolecular complex assembly GO:0065003 273 0.020
carboxylic acid transport GO:0046942 115 0.020
positive regulation of dopamine secretion GO:0033603 8 0.020
nucleoside triphosphate catabolic process GO:0009143 123 0.020
gamete generation GO:0007276 124 0.020
anion transport GO:0006820 178 0.019
negative regulation of cell development GO:0010721 82 0.019
cellular ketone metabolic process GO:0042180 51 0.019
regulation of peptide transport GO:0090087 87 0.019
sex differentiation GO:0007548 113 0.019
regulation of vasoconstriction GO:0019229 44 0.019
positive regulation of peptide hormone secretion GO:0090277 50 0.019
positive regulation of serotonin secretion GO:0014064 1 0.019
cardiac chamber development GO:0003205 1 0.019
response to morphine GO:0043278 27 0.019
response to growth factor GO:0070848 189 0.019
Rat
negative regulation of hormone secretion GO:0046888 46 0.019
positive regulation of synaptic vesicle transport GO:1902805 3 0.019
endocrine system development GO:0035270 30 0.019
positive regulation of nucleotide metabolic process GO:0045981 91 0.019
phospholipid metabolic process GO:0006644 61 0.018
digestive tract development GO:0048565 39 0.018
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.018
regulation of locomotion GO:0040012 148 0.018
Worm
axis specification GO:0009798 4 0.018
camp biosynthetic process GO:0006171 47 0.018
positive regulation of camp metabolic process GO:0030816 31 0.018
regulation of synaptic transmission gabaergic GO:0032228 17 0.018
homeostatic process GO:0042592 331 0.018
positive regulation of response to stimulus GO:0048584 285 0.018
regulation of cellular response to stress GO:0080135 49 0.017
protein localization GO:0008104 191 0.017
calcium ion homeostasis GO:0055074 162 0.017
drinking behavior GO:0042756 11 0.017
gliogenesis GO:0042063 93 0.017
adult locomotory behavior GO:0008344 4 0.017
calcium ion transport GO:0006816 131 0.017
Mouse
negative regulation of programmed cell death GO:0043069 183 0.017
heart process GO:0003015 57 0.017
epithelium development GO:0060429 96 0.017
actomyosin structure organization GO:0031032 22 0.017
multicellular organism growth GO:0035264 1 0.017
regulation of response to extracellular stimulus GO:0032104 11 0.017
guanosine containing compound metabolic process GO:1901068 74 0.017
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.016
serotonin receptor signaling pathway GO:0007210 10 0.016
Rat
gtp catabolic process GO:0006184 71 0.016
response to oxidative stress GO:0006979 186 0.016
Human
embryo development GO:0009790 49 0.016
locomotory exploration behavior GO:0035641 1 0.016
memory GO:0007613 54 0.016
positive regulation of appetite GO:0032100 2 0.016
muscle cell proliferation GO:0033002 84 0.016
second messenger mediated signaling GO:0019932 51 0.016
peptide transport GO:0015833 97 0.016
protein complex assembly GO:0006461 263 0.016
muscle tissue morphogenesis GO:0060415 1 0.016
regulation of ion transport GO:0043269 245 0.015
regulation of response to external stimulus GO:0032101 106 0.015
male gamete generation GO:0048232 99 0.015
synaptic vesicle transport GO:0048489 23 0.015
regulation of exocytosis GO:0017157 37 0.015
cell cycle GO:0007049 101 0.015
response to oxygen levels GO:0070482 265 0.015
Human

Chrna4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.062
disease of anatomical entity DOID:7 0 0.062
nervous system disease DOID:863 0 0.062
eye and adnexa disease DOID:1492 0 0.042
retinal disease DOID:5679 0 0.034
eye disease DOID:5614 0 0.034