Rattus norvegicus

38 known processes

Cit

citron

Cit biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid metabolic process GO:0019752 289 0.277
regulation of body fluid levels GO:0050878 90 0.193
regulation of secretion GO:0051046 224 0.184
lipid biosynthetic process GO:0008610 128 0.177
positive regulation of synaptic transmission GO:0050806 62 0.169
anion transport GO:0006820 178 0.161
regulation of cell proliferation GO:0042127 359 0.155
oxoacid metabolic process GO:0043436 290 0.133
chemical homeostasis GO:0048878 292 0.131
brain development GO:0007420 247 0.130
regulation of cellular component organization GO:0051128 368 0.122
positive regulation of transport GO:0051050 245 0.122
glutamate secretion GO:0014047 19 0.120
carboxylic acid transport GO:0046942 115 0.117
regulation of cellular localization GO:0060341 263 0.117
muscle contraction GO:0006936 88 0.115
regulation of secretion by cell GO:1903530 208 0.111
lipid metabolic process GO:0006629 283 0.105
reproductive process GO:0022414 372 0.101
regulation of anion transport GO:0044070 43 0.095
head development GO:0060322 247 0.094
cation transport GO:0006812 382 0.094
endocrine process GO:0050886 32 0.091
saliva secretion GO:0046541 3 0.089
organic acid metabolic process GO:0006082 292 0.089
secretion by cell GO:0032940 248 0.088
positive regulation of cellular biosynthetic process GO:0031328 295 0.088
neuron differentiation GO:0030182 368 0.085
catabolic process GO:0009056 351 0.085
cellular response to lipid GO:0071396 201 0.085
cell growth GO:0016049 104 0.084
ion transmembrane transport GO:0034220 365 0.076
cellular divalent inorganic cation homeostasis GO:0072503 162 0.075
cellular response to oxygen containing compound GO:1901701 386 0.075
single organism biosynthetic process GO:0044711 342 0.066
regulation of phosphorus metabolic process GO:0051174 349 0.063
response to nutrient levels GO:0031667 370 0.063
cell projection organization GO:0030030 302 0.063
metal ion homeostasis GO:0055065 186 0.063
organic acid transport GO:0015849 116 0.062
monocarboxylic acid transport GO:0015718 52 0.060
regulation of neuron differentiation GO:0045664 208 0.059
central nervous system development GO:0007417 311 0.059
organic anion transport GO:0015711 132 0.059
amine metabolic process GO:0009308 38 0.057
cellular amino acid metabolic process GO:0006520 107 0.056
response to extracellular stimulus GO:0009991 380 0.054
response to vitamin GO:0033273 131 0.054
regulation of cellular amine metabolic process GO:0033238 8 0.053
small molecule biosynthetic process GO:0044283 124 0.053
intracellular signal transduction GO:0035556 314 0.052
regulation of multicellular organismal development GO:2000026 376 0.052
response to inorganic substance GO:0010035 377 0.051
transmembrane transport GO:0055085 412 0.051
g protein coupled receptor signaling pathway GO:0007186 242 0.051
single organism catabolic process GO:0044712 283 0.050
nitrogen compound transport GO:0071705 229 0.050
regulation of synaptic transmission GO:0050804 141 0.050
signal release GO:0023061 145 0.049
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.049
response to corticosterone GO:0051412 40 0.049
phasic smooth muscle contraction GO:0014821 3 0.048
hormone transport GO:0009914 121 0.048
positive regulation of secretion GO:0051047 140 0.046
cellular ketone metabolic process GO:0042180 51 0.046
blood circulation GO:0008015 183 0.044
response to carbohydrate GO:0009743 183 0.044
cytosolic calcium ion homeostasis GO:0051480 140 0.044
regulation of cell development GO:0060284 263 0.044
positive regulation of cellular amine metabolic process GO:0033240 3 0.042
cell migration GO:0016477 197 0.042
positive regulation of nervous system development GO:0051962 178 0.041
tonic smooth muscle contraction GO:0014820 4 0.041
response to glucocorticoid GO:0051384 223 0.041
granulocyte migration GO:0097530 16 0.041
tissue development GO:0009888 252 0.040
regulation of cellular ketone metabolic process GO:0010565 27 0.040
cellular chemical homeostasis GO:0055082 247 0.040
cellular amine metabolic process GO:0044106 38 0.040
cellular response to organic cyclic compound GO:0071407 202 0.040
amide transport GO:0042886 105 0.040
homeostatic process GO:0042592 331 0.039
regulation of hormone levels GO:0010817 187 0.039
positive regulation of signal transduction GO:0009967 175 0.039
long term synaptic potentiation GO:0060291 21 0.039
regulation of membrane potential GO:0042391 110 0.039
cellular lipid metabolic process GO:0044255 208 0.038
regulation of postsynaptic membrane potential GO:0060078 25 0.038
regulation of rna metabolic process GO:0051252 391 0.038
purine nucleotide biosynthetic process GO:0006164 83 0.038
positive regulation of signaling GO:0023056 270 0.038
response to temperature stimulus GO:0009266 94 0.037
cell cell signaling GO:0007267 335 0.037
regulation of excitatory postsynaptic membrane potential GO:0060079 18 0.037
response to decreased oxygen levels GO:0036293 237 0.037
response to mechanical stimulus GO:0009612 134 0.037
regulation of signal transduction GO:0009966 318 0.037
cellular response to steroid hormone stimulus GO:0071383 93 0.036
smooth muscle contraction GO:0006939 37 0.036
organic substance catabolic process GO:1901575 316 0.035
positive regulation of glutamate secretion GO:0014049 8 0.035
cellular metal ion homeostasis GO:0006875 172 0.034
response to mineralocorticoid GO:0051385 49 0.034
prepulse inhibition GO:0060134 1 0.033
regulation of system process GO:0044057 208 0.033
positive regulation of cellular component organization GO:0051130 200 0.032
regulation of blood pressure GO:0008217 83 0.032
cellular response to stress GO:0033554 269 0.032
regulation of cellular amino acid metabolic process GO:0006521 2 0.032
response to nutrient GO:0007584 248 0.032
divalent inorganic cation transport GO:0072511 134 0.032
small gtpase mediated signal transduction GO:0007264 36 0.032
regulation of neurological system process GO:0031644 43 0.031
cellular component movement GO:0006928 248 0.031
organonitrogen compound biosynthetic process GO:1901566 167 0.031
positive regulation of developmental process GO:0051094 283 0.031
anion transmembrane transport GO:0098656 77 0.031
cyclic nucleotide metabolic process GO:0009187 80 0.031
nucleic acid templated transcription GO:0097659 379 0.031
response to camp GO:0051591 91 0.030
response to acid chemical GO:0001101 222 0.030
negative regulation of signaling GO:0023057 157 0.030
regulation of neuron projection development GO:0010975 161 0.030
cellular response to glucocorticoid stimulus GO:0071385 68 0.029
cellular response to insulin stimulus GO:0032869 81 0.029
lipid transport GO:0006869 61 0.029
cellular calcium ion homeostasis GO:0006874 160 0.029
response to heat GO:0009408 60 0.029
regulation of rna biosynthetic process GO:2001141 381 0.028
renin angiotensin regulation of aldosterone production GO:0002018 3 0.028
ras protein signal transduction GO:0007265 29 0.028
negative regulation of transport GO:0051051 136 0.027
response to ethanol GO:0045471 162 0.027
growth GO:0040007 165 0.027
cellular ion homeostasis GO:0006873 184 0.027
positive regulation of cell differentiation GO:0045597 217 0.027
cellular catabolic process GO:0044248 295 0.027
regulation of nervous system development GO:0051960 264 0.027
regulation of saliva secretion GO:0046877 3 0.027
carbohydrate derivative biosynthetic process GO:1901137 124 0.027
cellular response to hormone stimulus GO:0032870 247 0.026
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.026
positive regulation of organic acid transport GO:0032892 22 0.026
positive regulation of cell development GO:0010720 176 0.026
positive regulation of secretion by cell GO:1903532 128 0.026
forebrain development GO:0030900 98 0.026
organic hydroxy compound transport GO:0015850 77 0.026
angiotensin mediated drinking behavior GO:0003051 2 0.026
acid secretion GO:0046717 48 0.025
regulation of apoptotic process GO:0042981 335 0.025
regulation of glutamate secretion GO:0014048 17 0.025
neuron projection development GO:0031175 273 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.024
cation transmembrane transport GO:0098655 263 0.024
regulation of locomotion GO:0040012 148 0.024
taxis GO:0042330 67 0.024
negative regulation of secretion GO:0051048 82 0.024
positive regulation of cell migration GO:0030335 96 0.024
synaptic transmission GO:0007268 235 0.024
cellular response to external stimulus GO:0071496 118 0.024
artery smooth muscle contraction GO:0014824 4 0.024
tube development GO:0035295 89 0.024
response to ketone GO:1901654 182 0.024
carbohydrate derivative metabolic process GO:1901135 346 0.023
amine transport GO:0015837 57 0.023
macromolecule localization GO:0033036 252 0.023
regulation of organic acid transport GO:0032890 35 0.023
regulation of neurogenesis GO:0050767 247 0.023
regulation of response to external stimulus GO:0032101 106 0.023
positive regulation of leukocyte migration GO:0002687 21 0.023
muscle system process GO:0003012 115 0.023
organic hydroxy compound metabolic process GO:1901615 115 0.023
regulation of muscle system process GO:0090257 79 0.023
regulation of transferase activity GO:0051338 123 0.023
regulation of phosphate metabolic process GO:0019220 349 0.022
chemotaxis GO:0006935 66 0.022
carboxylic acid biosynthetic process GO:0046394 83 0.022
secretion GO:0046903 307 0.022
cellular response to acid chemical GO:0071229 75 0.022
circulatory system process GO:0003013 183 0.022
multi organism reproductive process GO:0044703 262 0.022
positive regulation of renin secretion into blood stream GO:1900135 1 0.022
membrane organization GO:0061024 94 0.022
sexual reproduction GO:0019953 148 0.022
biological adhesion GO:0022610 110 0.021
cellular response to organonitrogen compound GO:0071417 197 0.021
respiratory gaseous exchange GO:0007585 4 0.021
response to hypoxia GO:0001666 231 0.021
cardiovascular system development GO:0072358 134 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.021
ion homeostasis GO:0050801 212 0.021
positive regulation of phosphate metabolic process GO:0045937 262 0.021
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.021
cell cycle GO:0007049 101 0.020
cellular homeostasis GO:0019725 252 0.020
response to transition metal nanoparticle GO:1990267 122 0.020
negative regulation of ion transport GO:0043271 51 0.020
respiratory system process GO:0003016 3 0.020
response to peptide GO:1901652 292 0.020
cellular response to peptide hormone stimulus GO:0071375 120 0.020
positive regulation of cell death GO:0010942 184 0.020
peptidyl amino acid modification GO:0018193 126 0.020
response to oxygen levels GO:0070482 265 0.020
organ morphogenesis GO:0009887 75 0.020
regulation of ion transport GO:0043269 245 0.019
response to monoamine GO:0071867 17 0.019
cellular cation homeostasis GO:0030003 180 0.019
renal system process GO:0003014 40 0.019
regulation of cell differentiation GO:0045595 320 0.019
regulation of synaptic plasticity GO:0048167 70 0.019
antibiotic transport GO:0042891 2 0.019
regulation of molecular function GO:0065009 398 0.019
heart process GO:0003015 57 0.018
anterior posterior pattern specification GO:0009952 1 0.018
regulation of cell motility GO:2000145 131 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.018
phenol containing compound metabolic process GO:0018958 30 0.018
regulation of ion homeostasis GO:2000021 63 0.018
response to nicotine GO:0035094 51 0.018
regeneration GO:0031099 163 0.018
small molecule catabolic process GO:0044282 59 0.018
negative regulation of metabolic process GO:0009892 331 0.018
regulation of anatomical structure size GO:0090066 135 0.018
single organism cellular localization GO:1902580 102 0.018
regulation of peptide transport GO:0090087 87 0.018
single organism reproductive process GO:0044702 297 0.018
negative regulation of hormone secretion GO:0046888 46 0.018
regulation of catalytic activity GO:0050790 304 0.018
positive regulation of cell communication GO:0010647 271 0.018
multicellular organismal signaling GO:0035637 44 0.017
reactive nitrogen species metabolic process GO:2001057 1 0.017
negative regulation of cellular metabolic process GO:0031324 281 0.017
negative regulation of vasculature development GO:1901343 11 0.017
regulation of cell growth GO:0001558 85 0.017
muscle cell proliferation GO:0033002 84 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
regulation of peptide secretion GO:0002791 82 0.017
cellular response to growth factor stimulus GO:0071363 162 0.017
inner ear morphogenesis GO:0042472 1 0.017
limb morphogenesis GO:0035108 4 0.017
regulation of protein metabolic process GO:0051246 289 0.017
membrane depolarization GO:0051899 32 0.017
response to metal ion GO:0010038 253 0.016
regulation of nucleic acid templated transcription GO:1903506 380 0.016
regulation of transcription dna templated GO:0006355 374 0.016
cation homeostasis GO:0055080 195 0.016
cell motility GO:0048870 202 0.016
anatomical structure morphogenesis GO:0009653 298 0.016
inorganic ion transmembrane transport GO:0098660 229 0.016
regulation of synaptic transmission glutamatergic GO:0051966 26 0.016
divalent inorganic cation homeostasis GO:0072507 165 0.016
cellular response to mechanical stimulus GO:0071260 48 0.016
gamete generation GO:0007276 124 0.016
rna metabolic process GO:0016070 406 0.016
localization of cell GO:0051674 202 0.016
epithelium development GO:0060429 96 0.016
positive regulation of nucleic acid templated transcription GO:1903508 197 0.016
positive regulation of phosphorus metabolic process GO:0010562 262 0.016
negative regulation of macromolecule metabolic process GO:0010605 260 0.016
positive regulation of cellular component movement GO:0051272 102 0.016
positive regulation of transferase activity GO:0051347 81 0.015
endoplasmic reticulum to cytosol transport GO:1903513 4 0.015
sequestering of metal ion GO:0051238 9 0.015
chemosensory behavior GO:0007635 2 0.015
cardiac cell development GO:0055006 16 0.015
rho protein signal transduction GO:0007266 11 0.015
endomembrane system organization GO:0010256 48 0.015
positive regulation of amine transport GO:0051954 26 0.015
regulation of dendrite development GO:0050773 59 0.015
renal sodium excretion GO:0035812 20 0.015
protein phosphorylation GO:0006468 345 0.015
regulation of nucleotide metabolic process GO:0006140 117 0.015
regulation of protein modification process GO:0031399 194 0.015
locomotion GO:0040011 237 0.015
regulation of neurotransmitter levels GO:0001505 42 0.015
regulation of neuronal synaptic plasticity GO:0048168 31 0.015
vascular process in circulatory system GO:0003018 96 0.015
uterine smooth muscle contraction GO:0070471 10 0.015
regulation of cell adhesion GO:0030155 52 0.015
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.014
ribonucleotide biosynthetic process GO:0009260 85 0.014
regulation of phosphorylation GO:0042325 248 0.014
heterocycle catabolic process GO:0046700 167 0.014
organophosphate metabolic process GO:0019637 370 0.014
urinary bladder smooth muscle contraction GO:0014832 4 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
positive regulation of ion transport GO:0043270 94 0.014
metal ion transport GO:0030001 289 0.014
positive regulation of blood pressure GO:0045777 31 0.014
positive regulation of peptide secretion GO:0002793 52 0.014
response to cytokine GO:0034097 215 0.014
positive regulation of molecular function GO:0044093 230 0.014
response to oxidative stress GO:0006979 186 0.014
regulation of hormone secretion GO:0046883 106 0.014
organelle organization GO:0006996 266 0.014
hormone metabolic process GO:0042445 69 0.014
positive regulation of biosynthetic process GO:0009891 319 0.014
multicellular organism growth GO:0035264 1 0.014
response to insulin GO:0032868 133 0.014
response to reactive oxygen species GO:0000302 120 0.014
camp metabolic process GO:0046058 63 0.013
nucleotide metabolic process GO:0009117 279 0.013
neuron neuron synaptic transmission GO:0007270 60 0.013
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.013
positive regulation of amino acid transport GO:0051957 13 0.013
cellular response to alcohol GO:0097306 87 0.013
regulation of systemic arterial blood pressure GO:0003073 30 0.013
neuromuscular process GO:0050905 2 0.013
neuropeptide signaling pathway GO:0007218 29 0.013
brain renin angiotensin system GO:0002035 3 0.013
regulation of amine transport GO:0051952 54 0.013
second messenger mediated signaling GO:0019932 51 0.013
multicellular organism reproduction GO:0032504 233 0.013
positive regulation of long term synaptic potentiation GO:1900273 4 0.013
cellular response to nutrient levels GO:0031669 60 0.013
peptide transport GO:0015833 97 0.013
macromolecular complex subunit organization GO:0043933 339 0.013
n methyl d aspartate receptor clustering GO:0097114 2 0.013
single organism carbohydrate metabolic process GO:0044723 118 0.013
regulation of protein transport GO:0051223 68 0.013
axon development GO:0061564 96 0.013
glycosyl compound catabolic process GO:1901658 126 0.013
positive regulation of locomotion GO:0040017 102 0.013
single organismal cell cell adhesion GO:0016337 42 0.012
positive regulation of neurotransmitter transport GO:0051590 9 0.012
cell part morphogenesis GO:0032990 123 0.012
transcription from rna polymerase ii promoter GO:0006366 252 0.012
wound healing GO:0042060 122 0.012
regulation of long term neuronal synaptic plasticity GO:0048169 15 0.012
programmed cell death GO:0012501 392 0.012
regulation of small gtpase mediated signal transduction GO:0051056 48 0.012
nucleoside phosphate metabolic process GO:0006753 283 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
peptide hormone secretion GO:0030072 84 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
developmental growth GO:0048589 100 0.012
aging GO:0007568 241 0.012
cellular response to endogenous stimulus GO:0071495 377 0.012
negative regulation of protein maturation GO:1903318 47 0.012
regulation of programmed cell death GO:0043067 341 0.012
mapk cascade GO:0000165 140 0.012
positive regulation of gene expression GO:0010628 244 0.012
neuron development GO:0048666 286 0.012
sensory organ development GO:0007423 74 0.012
positive regulation of multicellular organismal process GO:0051240 387 0.012
purine containing compound catabolic process GO:0072523 138 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
endothelial cell proliferation GO:0001935 20 0.011
fatty acid transport GO:0015908 25 0.011
positive regulation of vasodilation GO:0045909 29 0.011
regulation of renin secretion into blood stream GO:1900133 1 0.011
multicellular organismal reproductive process GO:0048609 233 0.011
cellular response to oxygen levels GO:0071453 60 0.011
cardiac muscle hypertrophy GO:0003300 23 0.011
striated muscle tissue development GO:0014706 58 0.011
response to activity GO:0014823 73 0.011
single organism cell adhesion GO:0098602 46 0.011
monoamine transport GO:0015844 43 0.011
calcium ion homeostasis GO:0055074 162 0.011
regulation of cell cycle GO:0051726 73 0.011
endocytosis GO:0006897 84 0.011
cell communication involved in cardiac conduction GO:0086065 2 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
kidney development GO:0001822 67 0.011
adult locomotory behavior GO:0008344 4 0.011
pyruvate metabolic process GO:0006090 27 0.011
smooth muscle cell proliferation GO:0048659 77 0.011
oxidation reduction process GO:0055114 304 0.011
grooming behavior GO:0007625 4 0.011
cellular response to extracellular stimulus GO:0031668 73 0.011
male gamete generation GO:0048232 99 0.011
dna metabolic process GO:0006259 96 0.010
regulation of homeostatic process GO:0032844 101 0.010
regulation of endocrine process GO:0044060 21 0.010
positive regulation of protein kinase activity GO:0045860 73 0.010
spermatogenesis GO:0007283 99 0.010
regulation of inhibitory postsynaptic membrane potential GO:0060080 6 0.010
urinary tract smooth muscle contraction GO:0014848 4 0.010
icosanoid metabolic process GO:0006690 38 0.010
regulation of respiratory gaseous exchange GO:0043576 2 0.010
amino acid transport GO:0006865 70 0.010
regulation of intracellular signal transduction GO:1902531 218 0.010
circadian rhythm GO:0007623 88 0.010
glycerophospholipid metabolic process GO:0006650 47 0.010
cellular response to ketone GO:1901655 51 0.010
negative regulation of apoptotic process GO:0043066 181 0.010
cardiocyte differentiation GO:0035051 22 0.010
response to fatty acid GO:0070542 65 0.010
positive regulation of saliva secretion GO:0046878 3 0.010
muscle structure development GO:0061061 87 0.010
positive regulation of apoptotic process GO:0043065 154 0.010

Cit disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
substance dependence DOID:9973 0 0.029
substance related disorder DOID:303 0 0.029
disease of mental health DOID:150 0 0.029
sensory system disease DOID:0050155 0 0.014
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
eye and adnexa disease DOID:1492 0 0.013
organ system cancer DOID:0050686 0 0.011