Rattus norvegicus

69 known processes

Clock

clock homolog (mouse)

Clock biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
behavior GO:0007610 205 0.408
Fly
organic hydroxy compound metabolic process GO:1901615 115 0.305
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.252
Human Mouse Fly
positive regulation of signal transduction GO:0009967 175 0.207
regulation of molecular function GO:0065009 398 0.145
Mouse
cell cell signaling GO:0007267 335 0.139
Mouse
regulation of signal transduction GO:0009966 318 0.139
Mouse
rhythmic process GO:0048511 156 0.131
positive regulation of cell communication GO:0010647 271 0.130
neurological system process GO:0050877 219 0.124
regulation of phosphate metabolic process GO:0019220 349 0.097
regulation of mapk cascade GO:0043408 116 0.094
regulation of transcription dna templated GO:0006355 374 0.094
single organism behavior GO:0044708 130 0.093
Fly
intracellular signal transduction GO:0035556 314 0.081
regulation of phosphorus metabolic process GO:0051174 349 0.080
signal transduction by phosphorylation GO:0023014 144 0.079
multi organism reproductive process GO:0044703 262 0.078
Mouse
regulation of secretion by cell GO:1903530 208 0.074
Mouse
regulation of hormone levels GO:0010817 187 0.074
Mouse
protein complex biogenesis GO:0070271 263 0.072
negative regulation of cell death GO:0060548 229 0.072
cellular response to oxygen containing compound GO:1901701 386 0.070
transcription from rna polymerase ii promoter GO:0006366 252 0.070
Human Mouse Fly
positive regulation of phosphorus metabolic process GO:0010562 262 0.069
regulation of nucleic acid templated transcription GO:1903506 380 0.069
positive regulation of phosphate metabolic process GO:0045937 262 0.069
regulation of apoptotic process GO:0042981 335 0.066
regulation of phosphorylation GO:0042325 248 0.063
locomotion GO:0040011 237 0.062
homeostatic process GO:0042592 331 0.062
nucleic acid templated transcription GO:0097659 379 0.062
positive regulation of signaling GO:0023056 270 0.061
rna biosynthetic process GO:0032774 380 0.061
protein complex assembly GO:0006461 263 0.060
positive regulation of response to stimulus GO:0048584 285 0.059
Mouse
positive regulation of phosphorylation GO:0042327 177 0.059
circulatory system process GO:0003013 183 0.059
metal ion homeostasis GO:0055065 186 0.058
cellular response to stress GO:0033554 269 0.057
Human
protein phosphorylation GO:0006468 345 0.056
carbohydrate derivative metabolic process GO:1901135 346 0.055
smooth muscle cell proliferation GO:0048659 77 0.054
synaptic transmission GO:0007268 235 0.054
neuron development GO:0048666 286 0.054
ion homeostasis GO:0050801 212 0.054
mapk cascade GO:0000165 140 0.054
muscle cell proliferation GO:0033002 84 0.053
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.053
Human Mouse Fly
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.053
transcription dna templated GO:0006351 377 0.053
negative regulation of apoptotic process GO:0043066 181 0.052
regulation of protein modification process GO:0031399 194 0.052
rna metabolic process GO:0016070 406 0.051
learning or memory GO:0007611 90 0.051
organophosphate metabolic process GO:0019637 370 0.050
alcohol metabolic process GO:0006066 77 0.050
regulation of programmed cell death GO:0043067 341 0.050
reproductive process GO:0022414 372 0.050
Mouse
regulation of catalytic activity GO:0050790 304 0.049
sensory perception GO:0007600 101 0.049
regulation of anatomical structure size GO:0090066 135 0.049
circadian rhythm GO:0007623 88 0.049
aging GO:0007568 241 0.048
male mating behavior GO:0060179 3 0.048
amine metabolic process GO:0009308 38 0.048
stress activated protein kinase signaling cascade GO:0031098 37 0.048
positive regulation of cell proliferation GO:0008284 249 0.048
response to oxidative stress GO:0006979 186 0.047
response to acid chemical GO:0001101 222 0.046
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.046
response to hypoxia GO:0001666 231 0.045
catabolic process GO:0009056 351 0.045
Mouse
positive regulation of cellular biosynthetic process GO:0031328 295 0.045
cellular component assembly GO:0022607 360 0.045
cellular component movement GO:0006928 248 0.044
multicellular organism reproduction GO:0032504 233 0.044
Mouse
positive regulation of multicellular organismal process GO:0051240 387 0.044
regulation of cellular protein metabolic process GO:0032268 267 0.043
sensory perception of pain GO:0019233 73 0.043
multicellular organismal reproductive process GO:0048609 233 0.042
Mouse
regulation of protein metabolic process GO:0051246 289 0.042
response to light stimulus GO:0009416 52 0.042
Zebrafish
cell projection organization GO:0030030 302 0.042
negative regulation of transport GO:0051051 136 0.042
positive regulation of transcription dna templated GO:0045893 197 0.042
protein homooligomerization GO:0051260 91 0.042
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.042
Mouse
negative regulation of secretion by cell GO:1903531 72 0.041
positive regulation of mapk cascade GO:0043410 92 0.041
apoptotic process GO:0006915 381 0.041
regulation of smooth muscle cell proliferation GO:0048660 75 0.041
regulation of membrane potential GO:0042391 110 0.040
regulation of neuron apoptotic process GO:0043523 83 0.040
regulation of secretion GO:0051046 224 0.040
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 162 0.040
cellular amine metabolic process GO:0044106 38 0.040
brain development GO:0007420 247 0.039
reproduction GO:0000003 245 0.039
Mouse
regulation of rna biosynthetic process GO:2001141 381 0.038
regulation of nervous system development GO:0051960 264 0.038
regulation of protein phosphorylation GO:0001932 183 0.037
positive regulation of intracellular signal transduction GO:1902533 138 0.036
regulation of cell motility GO:2000145 131 0.036
ion transmembrane transport GO:0034220 365 0.036
protein complex subunit organization GO:0071822 302 0.036
cellular homeostasis GO:0019725 252 0.036
response to radiation GO:0009314 137 0.035
Human Zebrafish
signal release GO:0023061 145 0.035
Mouse
single organism biosynthetic process GO:0044711 342 0.035
macromolecular complex assembly GO:0065003 273 0.035
organic hydroxy compound biosynthetic process GO:1901617 51 0.035
programmed cell death GO:0012501 392 0.035
cellular component biogenesis GO:0044085 368 0.035
sexual reproduction GO:0019953 148 0.034
Mouse
secretion by cell GO:0032940 248 0.034
Mouse
feeding behavior GO:0007631 53 0.034
negative regulation of programmed cell death GO:0043069 183 0.033
single organism reproductive process GO:0044702 297 0.033
Mouse
single organism catabolic process GO:0044712 283 0.033
epithelium development GO:0060429 96 0.032
Mouse
blood circulation GO:0008015 183 0.032
positive regulation of developmental process GO:0051094 283 0.032
cellular amino acid metabolic process GO:0006520 107 0.031
cellular hormone metabolic process GO:0034754 49 0.031
vascular process in circulatory system GO:0003018 96 0.031
head development GO:0060322 247 0.031
anatomical structure morphogenesis GO:0009653 298 0.031
nucleobase containing small molecule metabolic process GO:0055086 316 0.031
neuron death GO:0070997 127 0.030
lipid metabolic process GO:0006629 283 0.030
divalent inorganic cation homeostasis GO:0072507 165 0.030
positive regulation of nucleic acid templated transcription GO:1903508 197 0.029
regulation of cellular amine metabolic process GO:0033238 8 0.029
cellular response to abiotic stimulus GO:0071214 85 0.028
Human
female sex differentiation GO:0046660 59 0.028
neuron differentiation GO:0030182 368 0.028
positive regulation of catalytic activity GO:0043085 184 0.027
regulation of tube size GO:0035150 89 0.027
negative regulation of metabolic process GO:0009892 331 0.027
Mouse
cation transport GO:0006812 382 0.027
positive regulation of rna biosynthetic process GO:1902680 197 0.027
protein heterooligomerization GO:0051291 89 0.026
regulation of cellular ketone metabolic process GO:0010565 27 0.026
small gtpase mediated signal transduction GO:0007264 36 0.026
regulation of neuron death GO:1901214 115 0.026
cation transmembrane transport GO:0098655 263 0.026
regulation of system process GO:0044057 208 0.026
positive regulation of phagocytosis engulfment GO:0060100 4 0.026
regulation of kinase activity GO:0043549 117 0.025
response to retinoic acid GO:0032526 63 0.025
regulation of cell projection organization GO:0031344 175 0.025
regulation of neurogenesis GO:0050767 247 0.025
locomotory behavior GO:0007626 15 0.025
Fly
tissue development GO:0009888 252 0.025
Mouse
isoprenoid metabolic process GO:0006720 45 0.025
inorganic ion transmembrane transport GO:0098660 229 0.024
response to hexose GO:0009746 144 0.024
regulation of synaptic transmission GO:0050804 141 0.024
carbohydrate metabolic process GO:0005975 130 0.024
cellular lipid metabolic process GO:0044255 208 0.024
response to monosaccharide GO:0034284 159 0.024
regulation of transferase activity GO:0051338 123 0.023
positive regulation of cellular protein metabolic process GO:0032270 167 0.023
peptidyl amino acid modification GO:0018193 126 0.023
Human Mouse
response to other organism GO:0051707 220 0.023
developmental process involved in reproduction GO:0003006 159 0.022
hormone secretion GO:0046879 115 0.022
Mouse
wound healing GO:0042060 122 0.022
negative regulation of cell communication GO:0010648 158 0.022
Mouse
reproductive structure development GO:0048608 128 0.022
regulation of peptide transport GO:0090087 87 0.022
Mouse
regulation of protein kinase activity GO:0045859 105 0.022
regulation of hormone secretion GO:0046883 106 0.021
Mouse
positive regulation of protein modification process GO:0031401 142 0.021
regulation of cellular response to stress GO:0080135 49 0.021
cellular ketone metabolic process GO:0042180 51 0.021
organonitrogen compound catabolic process GO:1901565 179 0.021
multi multicellular organism process GO:0044706 138 0.021
regulation of rna metabolic process GO:0051252 391 0.021
positive regulation of molecular function GO:0044093 230 0.021
Mouse
cation homeostasis GO:0055080 195 0.021
cellular ion homeostasis GO:0006873 184 0.021
cellular carbohydrate metabolic process GO:0044262 72 0.021
pancreatic stellate cell proliferation GO:0072343 2 0.020
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.020
exploration behavior GO:0035640 1 0.020
chemical homeostasis GO:0048878 292 0.020
oxoacid metabolic process GO:0043436 290 0.020
negative regulation of multicellular organismal process GO:0051241 203 0.020
response to estradiol GO:0032355 164 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
cellular chemical homeostasis GO:0055082 247 0.019
regulation of cell development GO:0060284 263 0.019
Mouse
regulation of intracellular signal transduction GO:1902531 218 0.019
response to reactive oxygen species GO:0000302 120 0.019
regulation of organ formation GO:0003156 2 0.019
cellular catabolic process GO:0044248 295 0.019
Mouse
monocarboxylic acid metabolic process GO:0032787 152 0.019
negative regulation of hormone secretion GO:0046888 46 0.018
regulation of cellular localization GO:0060341 263 0.018
Mouse
response to alkaloid GO:0043279 132 0.018
positive regulation of gene expression GO:0010628 244 0.018
positive regulation of protein metabolic process GO:0051247 178 0.018
rho protein signal transduction GO:0007266 11 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.018
cellular response to organic cyclic compound GO:0071407 202 0.018
circulatory system development GO:0072359 134 0.018
metal ion transport GO:0030001 289 0.018
vesicle mediated transport GO:0016192 181 0.018
nucleoside phosphate metabolic process GO:0006753 283 0.018
regulation of response to external stimulus GO:0032101 106 0.017
Mouse
aromatic compound catabolic process GO:0019439 168 0.017
sex differentiation GO:0007548 113 0.017
ribonucleotide metabolic process GO:0009259 231 0.017
response to nutrient levels GO:0031667 370 0.017
negative regulation of cellular metabolic process GO:0031324 281 0.017
Mouse
ras protein signal transduction GO:0007265 29 0.017
negative regulation of signaling GO:0023057 157 0.017
Mouse
phototransduction visible light GO:0007603 2 0.017
actin filament based process GO:0030029 86 0.017
development of primary female sexual characteristics GO:0046545 56 0.017
protein oligomerization GO:0051259 191 0.017
positive regulation of protein phosphorylation GO:0001934 135 0.017
cellular response to reactive oxygen species GO:0034614 55 0.017
ribonucleotide catabolic process GO:0009261 136 0.016
calcium ion homeostasis GO:0055074 162 0.016
neuron apoptotic process GO:0051402 88 0.016
positive regulation of kinase activity GO:0033674 77 0.016
purine containing compound metabolic process GO:0072521 253 0.016
cellular biogenic amine metabolic process GO:0006576 30 0.016
cell growth GO:0016049 104 0.016
cognition GO:0050890 92 0.016
organophosphate catabolic process GO:0046434 148 0.016
regulation of neuron projection development GO:0010975 161 0.015
regulation of cell differentiation GO:0045595 320 0.015
Mouse
response to glucose GO:0009749 136 0.015
maintenance of location GO:0051235 17 0.015
angiogenesis GO:0001525 53 0.015
response to decreased oxygen levels GO:0036293 237 0.015
positive regulation of transferase activity GO:0051347 81 0.015
negative regulation of molecular function GO:0044092 133 0.015
single organism carbohydrate metabolic process GO:0044723 118 0.015
response to oxygen levels GO:0070482 265 0.015
purine nucleotide metabolic process GO:0006163 229 0.014
regulation of purine nucleotide metabolic process GO:1900542 115 0.014
steroid metabolic process GO:0008202 73 0.014
forebrain development GO:0030900 98 0.014
response to external biotic stimulus GO:0043207 221 0.014
camp metabolic process GO:0046058 63 0.014
central nervous system development GO:0007417 311 0.014
positive regulation of nervous system development GO:0051962 178 0.014
response to electrical stimulus GO:0051602 56 0.014
regulation of blood pressure GO:0008217 83 0.014
regulation of peptide secretion GO:0002791 82 0.014
Mouse
nucleotide metabolic process GO:0009117 279 0.014
regulation of metal ion transport GO:0010959 118 0.014
nitrogen compound transport GO:0071705 229 0.014
Mouse
response to nutrient GO:0007584 248 0.014
response to carbohydrate GO:0009743 183 0.014
intracellular transport GO:0046907 185 0.014
divalent metal ion transport GO:0070838 132 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
glycosyl compound catabolic process GO:1901658 126 0.013
response to wounding GO:0009611 254 0.013
Mouse
protein tetramerization GO:0051262 38 0.013
regulation of cell proliferation GO:0042127 359 0.013
positive regulation of biosynthetic process GO:0009891 319 0.013
transmembrane transport GO:0055085 412 0.013
specification of organ identity GO:0010092 2 0.013
cellular response to lipid GO:0071396 201 0.013
phenol containing compound metabolic process GO:0018958 30 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
cellular cation homeostasis GO:0030003 180 0.013
organic cyclic compound catabolic process GO:1901361 175 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
positive regulation of nucleotide metabolic process GO:0045981 91 0.013
regulation of catabolic process GO:0009894 113 0.013
blood vessel morphogenesis GO:0048514 58 0.013
regulation of blood vessel size GO:0050880 89 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
macromolecular complex subunit organization GO:0043933 339 0.012
Human Mouse
cellular response to glucocorticoid stimulus GO:0071385 68 0.012
ribose phosphate biosynthetic process GO:0046390 87 0.012
nucleotide catabolic process GO:0009166 139 0.012
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.012
regulation of response to stress GO:0080134 126 0.012
Mouse
terpenoid metabolic process GO:0006721 37 0.012
small molecule biosynthetic process GO:0044283 124 0.012
organic substance catabolic process GO:1901575 316 0.012
Mouse
development of primary sexual characteristics GO:0045137 107 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
inflammatory response GO:0006954 150 0.012
Mouse
purine ribonucleoside metabolic process GO:0046128 168 0.012
carboxylic acid metabolic process GO:0019752 289 0.012
cell cell signaling involved in cell fate commitment GO:0045168 2 0.012
neuron neuron synaptic transmission GO:0007270 60 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
regulation of homeostatic process GO:0032844 101 0.012
locomotor rhythm GO:0045475 1 0.012
Fly
positive regulation of cell motility GO:2000147 97 0.012
response to ketone GO:1901654 182 0.012
purine ribonucleotide catabolic process GO:0009154 136 0.012
regulation of muscle system process GO:0090257 79 0.012
regulation of ion transport GO:0043269 245 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
lipid biosynthetic process GO:0008610 128 0.012
regulation of blood circulation GO:1903522 110 0.012
response to inorganic substance GO:0010035 377 0.012
negative regulation of smooth muscle cell proliferation GO:0048662 21 0.012
neuron projection development GO:0031175 273 0.012
organic acid metabolic process GO:0006082 292 0.012
detection of visible light GO:0009584 3 0.012
heart development GO:0007507 72 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 39 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.011
positive regulation of serotonin secretion GO:0014064 1 0.011
hormone metabolic process GO:0042445 69 0.011
cell motility GO:0048870 202 0.011
peptide hormone secretion GO:0030072 84 0.011
Mouse
detection of stimulus GO:0051606 24 0.011
vasodilation GO:0042311 44 0.011
regulation of g protein coupled receptor protein signaling pathway GO:0008277 28 0.011
regulation of cellular component organization GO:0051128 368 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
negative regulation of ion transport GO:0043271 51 0.011
locomotory exploration behavior GO:0035641 1 0.011
response to cytokine GO:0034097 215 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
organelle organization GO:0006996 266 0.011
Human Mouse
blood vessel development GO:0001568 69 0.011
response to metformin GO:1901558 1 0.011
jnk cascade GO:0007254 28 0.011
regulation of locomotion GO:0040012 148 0.011
adult locomotory behavior GO:0008344 4 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
localization of cell GO:0051674 202 0.011
growth GO:0040007 165 0.011
axis specification GO:0009798 4 0.011
negative regulation of secretion GO:0051048 82 0.011
adult behavior GO:0030534 16 0.011
positive regulation of gtp catabolic process GO:0033126 48 0.011
response to metal ion GO:0010038 253 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
negative regulation of gene expression GO:0010629 199 0.011
Mouse
purine nucleotide catabolic process GO:0006195 136 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
l glutamate import GO:0051938 2 0.011
amide transport GO:0042886 105 0.011
Mouse
negative regulation of response to stimulus GO:0048585 155 0.010
Mouse
spermatogenesis GO:0007283 99 0.010
Mouse
calcium ion transport GO:0006816 131 0.010
cellular response to oxygen levels GO:0071453 60 0.010
regulation of neuron differentiation GO:0045664 208 0.010
positive regulation of peptide secretion GO:0002793 52 0.010
negative regulation of luteinizing hormone secretion GO:0033685 4 0.010
negative regulation of neuron death GO:1901215 69 0.010
negative regulation of camp metabolic process GO:0030815 14 0.010
epiboly GO:0090504 2 0.010
cardiovascular system development GO:0072358 134 0.010
endocytosis GO:0006897 84 0.010
negative regulation of cellular biosynthetic process GO:0031327 161 0.010
Mouse
cytoplasmic transport GO:0016482 115 0.010
anion transport GO:0006820 178 0.010

Clock disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.040
nervous system disease DOID:863 0 0.040
central nervous system disease DOID:331 0 0.013
sensory system disease DOID:0050155 0 0.012