Rattus norvegicus

73 known processes

Cma1

chymase 1, mast cell

(Aliases: MCP3P,Mcpt5)

Cma1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of necroptotic process GO:0060545 2 0.552
hepatocyte proliferation GO:0072574 3 0.396
necroptotic process GO:0070266 2 0.319
positive regulation of necrotic cell death GO:0010940 4 0.300
programmed necrotic cell death GO:0097300 2 0.256
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.240
regulation of hemostasis GO:1900046 9 0.204
positive regulation of transport GO:0051050 245 0.179
epithelial cell proliferation involved in liver morphogenesis GO:0072575 3 0.174
positive regulation of multicellular organismal process GO:0051240 387 0.166
response to inorganic substance GO:0010035 377 0.149
neuron differentiation GO:0030182 368 0.139
response to hexose GO:0009746 144 0.126
negative regulation of wound healing GO:0061045 8 0.122
proteolysis GO:0006508 175 0.118
response to low density lipoprotein particle GO:0055098 4 0.112
cell adhesion GO:0007155 110 0.111
response to biotic stimulus GO:0009607 226 0.099
blood coagulation GO:0007596 26 0.096
regulation of blood coagulation GO:0030193 9 0.095
positive regulation of cell death GO:0010942 184 0.094
biological adhesion GO:0022610 110 0.089
single organism biosynthetic process GO:0044711 342 0.085
negative regulation of hemostasis GO:1900047 6 0.083
receptor metabolic process GO:0043112 18 0.082
regulation of extracellular matrix constituent secretion GO:0003330 2 0.081
ion transmembrane transport GO:0034220 365 0.081
blood circulation GO:0008015 183 0.081
regulation of coagulation GO:0050818 11 0.079
negative regulation of coagulation GO:0050819 7 0.079
macromolecular complex assembly GO:0065003 273 0.078
head development GO:0060322 247 0.077
carbohydrate metabolic process GO:0005975 130 0.075
extracellular matrix constituent secretion GO:0070278 4 0.073
chemical homeostasis GO:0048878 292 0.073
coagulation GO:0050817 28 0.071
regulation of multicellular organismal development GO:2000026 376 0.070
homeostatic process GO:0042592 331 0.068
fibrinolysis GO:0042730 2 0.067
macromolecule localization GO:0033036 252 0.067
regulation of cellular component movement GO:0051270 150 0.067
regulation of secretion GO:0051046 224 0.066
positive regulation of extracellular matrix organization GO:1903055 4 0.065
response to organophosphorus GO:0046683 102 0.064
positive regulation of cellular component organization GO:0051130 200 0.063
small molecule biosynthetic process GO:0044283 124 0.063
regulation of cell proliferation GO:0042127 359 0.062
behavior GO:0007610 205 0.062
cellular chemical homeostasis GO:0055082 247 0.059
hepaticobiliary system development GO:0061008 90 0.058
hemostasis GO:0007599 26 0.057
ion homeostasis GO:0050801 212 0.057
gland development GO:0048732 155 0.056
negative regulation of blood coagulation GO:0030195 6 0.056
cell activation GO:0001775 97 0.053
negative regulation of metabolic process GO:0009892 331 0.053
regulation of blood pressure GO:0008217 83 0.052
regulation of homotypic cell cell adhesion GO:0034110 4 0.052
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.050
organ morphogenesis GO:0009887 75 0.048
negative regulation of response to stimulus GO:0048585 155 0.048
regulation of necroptotic process GO:0060544 2 0.047
cellular response to low density lipoprotein particle stimulus GO:0071404 3 0.046
response to monosaccharide GO:0034284 159 0.045
organonitrogen compound catabolic process GO:1901565 179 0.045
sodium ion transport GO:0006814 82 0.045
circulatory system process GO:0003013 183 0.045
response to bacterium GO:0009617 200 0.045
response to purine containing compound GO:0014074 126 0.045
response to metal ion GO:0010038 253 0.044
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure GO:0002025 1 0.044
rna metabolic process GO:0016070 406 0.043
catabolic process GO:0009056 351 0.043
transmembrane transport GO:0055085 412 0.042
organic substance catabolic process GO:1901575 316 0.042
oxoacid metabolic process GO:0043436 290 0.041
carboxylic acid metabolic process GO:0019752 289 0.041
regulation of fibrinolysis GO:0051917 2 0.040
regulation of cell adhesion GO:0030155 52 0.040
cellular component biogenesis GO:0044085 368 0.040
positive regulation of secretion GO:0051047 140 0.040
positive regulation of wound healing GO:0090303 6 0.039
membrane hyperpolarization GO:0060081 11 0.038
urinary tract smooth muscle contraction GO:0014848 4 0.038
regulation of renin secretion into blood stream GO:1900133 1 0.038
regulation of anatomical structure morphogenesis GO:0022603 141 0.037
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 1 0.037
anion transport GO:0006820 178 0.035
response to toxic substance GO:0009636 133 0.035
embryonic hindlimb morphogenesis GO:0035116 2 0.035
liver morphogenesis GO:0072576 3 0.035
defense response GO:0006952 194 0.035
transcription dna templated GO:0006351 377 0.035
protein complex biogenesis GO:0070271 263 0.035
gland morphogenesis GO:0022612 12 0.035
regulation of response to wounding GO:1903034 69 0.034
organophosphate biosynthetic process GO:0090407 143 0.034
rna biosynthetic process GO:0032774 380 0.033
n methyl d aspartate receptor clustering GO:0097114 2 0.033
reproductive process GO:0022414 372 0.033
negative regulation of response to external stimulus GO:0032102 37 0.033
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 2 0.033
liver development GO:0001889 90 0.033
response to other organism GO:0051707 220 0.032
locomotion GO:0040011 237 0.032
negative regulation of fibrinolysis GO:0051918 2 0.032
regulation of cellular component organization GO:0051128 368 0.032
positive regulation of cell differentiation GO:0045597 217 0.032
monovalent inorganic cation transport GO:0015672 172 0.032
regeneration GO:0031099 163 0.031
regulation of nucleic acid templated transcription GO:1903506 380 0.031
cell motility GO:0048870 202 0.031
vesicle mediated transport GO:0016192 181 0.031
regulation of calcium ion transport GO:0051924 77 0.031
ras protein signal transduction GO:0007265 29 0.031
cellular component movement GO:0006928 248 0.031
positive regulation of immune system process GO:0002684 90 0.031
response to external biotic stimulus GO:0043207 221 0.030
response to wounding GO:0009611 254 0.030
regulation of platelet activation GO:0010543 2 0.030
positive regulation of blood coagulation GO:0030194 4 0.030
response to cytokine GO:0034097 215 0.030
cytosolic calcium ion homeostasis GO:0051480 140 0.030
positive regulation of the force of heart contraction by epinephrine GO:0003059 1 0.030
organonitrogen compound biosynthetic process GO:1901566 167 0.030
response to peptide hormone GO:0043434 278 0.029
positive regulation of programmed cell death GO:0043068 157 0.029
response to temperature stimulus GO:0009266 94 0.029
positive regulation of cell proliferation GO:0008284 249 0.028
nitrogen compound transport GO:0071705 229 0.028
small gtpase mediated signal transduction GO:0007264 36 0.027
positive regulation of the force of heart contraction by norepinephrine GO:0003061 1 0.027
response to carbohydrate GO:0009743 183 0.027
cation transmembrane transport GO:0098655 263 0.027
regulation of angiotensin metabolic process GO:0060177 3 0.027
regulation of the force of heart contraction by chemical signal GO:0003057 2 0.027
secretion GO:0046903 307 0.027
regulation of systemic arterial blood pressure GO:0003073 30 0.027
cellular homeostasis GO:0019725 252 0.027
cellular response to oxygen containing compound GO:1901701 386 0.026
respiratory gaseous exchange GO:0007585 4 0.026
organelle organization GO:0006996 266 0.026
single organism carbohydrate metabolic process GO:0044723 118 0.026
purine nucleotide metabolic process GO:0006163 229 0.026
carbohydrate homeostasis GO:0033500 75 0.026
multi organism reproductive process GO:0044703 262 0.026
cellular divalent inorganic cation homeostasis GO:0072503 162 0.025
cell projection organization GO:0030030 302 0.025
amine metabolic process GO:0009308 38 0.025
plasminogen activation GO:0031639 2 0.025
positive regulation of coagulation GO:0050820 5 0.025
regulation of protein metabolic process GO:0051246 289 0.025
morphogenesis of an epithelium GO:0002009 20 0.025
endocytosis GO:0006897 84 0.024
cellular polysaccharide metabolic process GO:0044264 23 0.024
neurotransmitter gated ion channel clustering GO:0072578 3 0.024
macromolecular complex subunit organization GO:0043933 339 0.024
programmed cell death GO:0012501 392 0.024
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.024
protein oligomerization GO:0051259 191 0.024
positive regulation of renin secretion into blood stream GO:1900135 1 0.024
prostate gland epithelium morphogenesis GO:0060740 2 0.023
divalent inorganic cation transport GO:0072511 134 0.023
synaptic transmission GO:0007268 235 0.023
regulation of response to external stimulus GO:0032101 106 0.023
cellular ion homeostasis GO:0006873 184 0.023
immune system process GO:0002376 204 0.023
regulation of system process GO:0044057 208 0.023
diaphragm contraction GO:0002086 2 0.023
positive regulation of molecular function GO:0044093 230 0.023
anatomical structure morphogenesis GO:0009653 298 0.023
negative regulation of multicellular organismal process GO:0051241 203 0.023
response to indole 3 methanol GO:0071680 2 0.023
multicellular organism reproduction GO:0032504 233 0.023
involuntary skeletal muscle contraction GO:0003011 2 0.023
cell migration GO:0016477 197 0.023
wound healing GO:0042060 122 0.022
regulation of organ morphogenesis GO:2000027 22 0.022
positive regulation of biosynthetic process GO:0009891 319 0.022
protein localization GO:0008104 191 0.022
cation homeostasis GO:0055080 195 0.022
regulation of molecular function GO:0065009 398 0.022
regulation of canonical wnt signaling pathway GO:0060828 4 0.022
cellular response to nitrogen compound GO:1901699 210 0.022
organ regeneration GO:0031100 101 0.022
cellular metal ion homeostasis GO:0006875 172 0.021
positive regulation of cellular biosynthetic process GO:0031328 295 0.021
regulation of wound healing GO:0061041 14 0.021
cellular cation homeostasis GO:0030003 180 0.021
positive regulation of microtubule polymerization or depolymerization GO:0031112 7 0.021
divalent metal ion transport GO:0070838 132 0.021
cellular amine metabolic process GO:0044106 38 0.021
regulation of ion transport GO:0043269 245 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
establishment of protein localization GO:0045184 141 0.021
protein transport GO:0015031 132 0.021
cell cell signaling GO:0007267 335 0.021
neuron development GO:0048666 286 0.020
renin secretion into blood stream GO:0002001 1 0.020
response to decreased oxygen levels GO:0036293 237 0.020
regulation of systemic arterial blood pressure by norepinephrine epinephrine GO:0001993 2 0.020
positive regulation of hemostasis GO:1900048 4 0.020
cellular response to growth factor stimulus GO:0071363 162 0.020
regulation of plasminogen activation GO:0010755 2 0.020
cation transport GO:0006812 382 0.020
regulation of hormone levels GO:0010817 187 0.020
organic hydroxy compound biosynthetic process GO:1901617 51 0.020
regulation of transcription dna templated GO:0006355 374 0.020
regulation of b cell mediated immunity GO:0002712 2 0.020
cellular response to biotic stimulus GO:0071216 59 0.019
regulation of immunoglobulin mediated immune response GO:0002889 2 0.019
cellular response to fluid shear stress GO:0071498 4 0.019
regulation of programmed cell death GO:0043067 341 0.019
alcohol biosynthetic process GO:0046165 38 0.019
positive regulation of developmental process GO:0051094 283 0.019
single organism catabolic process GO:0044712 283 0.019
erythrocyte aggregation GO:0034117 1 0.019
response to glucose GO:0009749 136 0.019
response to nutrient GO:0007584 248 0.019
reproduction GO:0000003 245 0.018
regulation of cell motility GO:2000145 131 0.018
g protein coupled receptor signaling pathway GO:0007186 242 0.018
epithelial cell proliferation GO:0050673 54 0.018
organophosphate metabolic process GO:0019637 370 0.018
saliva secretion GO:0046541 3 0.018
negative regulation of developmental process GO:0051093 125 0.018
lipid biosynthetic process GO:0008610 128 0.018
regulation of phosphate metabolic process GO:0019220 349 0.018
positive regulation of signal transduction GO:0009967 175 0.018
multicellular organismal catabolic process GO:0044243 2 0.018
positive regulation of long term synaptic potentiation GO:1900273 4 0.018
regulation of blood vessel size GO:0050880 89 0.018
regulation of protein secretion GO:0050708 28 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
monocarboxylic acid biosynthetic process GO:0072330 48 0.017
single organism reproductive process GO:0044702 297 0.017
hindlimb morphogenesis GO:0035137 2 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
secretion by cell GO:0032940 248 0.017
regulation of response to stress GO:0080134 126 0.017
regulation of signal transduction GO:0009966 318 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
oxidation reduction process GO:0055114 304 0.017
regulation of metal ion transport GO:0010959 118 0.017
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
nucleobase containing compound catabolic process GO:0034655 152 0.017
axis specification GO:0009798 4 0.017
response to extracellular stimulus GO:0009991 380 0.017
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.017
regulation of anatomical structure size GO:0090066 135 0.017
regulation of rna biosynthetic process GO:2001141 381 0.017
aging GO:0007568 241 0.016
heterocycle catabolic process GO:0046700 167 0.016
regulation of transmembrane transporter activity GO:0022898 49 0.016
response to corticosteroid GO:0031960 235 0.016
catecholamine transport GO:0051937 37 0.016
response to camp GO:0051591 91 0.016
urinary bladder smooth muscle contraction GO:0014832 4 0.016
neurological system process GO:0050877 219 0.016
single organism cell adhesion GO:0098602 46 0.016
energy derivation by oxidation of organic compounds GO:0015980 46 0.016
regulation of cell differentiation GO:0045595 320 0.016
prostate gland morphogenesis GO:0060512 2 0.016
positive regulation of response to stimulus GO:0048584 285 0.016
negative regulation of protein processing GO:0010955 47 0.016
regulation of membrane potential GO:0042391 110 0.016
protein processing GO:0016485 68 0.016
regulation of synaptic transmission GO:0050804 141 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.016
cytoplasmic transport GO:0016482 115 0.016
negative regulation of uterine smooth muscle contraction GO:0070473 2 0.016
cellular macromolecule localization GO:0070727 122 0.016
response to increased oxygen levels GO:0036296 45 0.016
canalicular bile acid transport GO:0015722 5 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
cellular component assembly GO:0022607 360 0.015
positive regulation of ion transport GO:0043270 94 0.015
cellular response to iron iii ion GO:0071283 3 0.015
organic hydroxy compound transport GO:0015850 77 0.015
nucleoside phosphate catabolic process GO:1901292 140 0.015
metal ion transport GO:0030001 289 0.015
response to high light intensity GO:0009644 1 0.015
monoamine transport GO:0015844 43 0.015
embryonic appendage morphogenesis GO:0035113 4 0.015
rho protein signal transduction GO:0007266 11 0.015
metal ion homeostasis GO:0055065 186 0.015
regulation of catalytic activity GO:0050790 304 0.015
cellular catabolic process GO:0044248 295 0.015
regulation of angiotensin levels in blood GO:0002002 2 0.015
positive regulation of secretion by cell GO:1903532 128 0.015
regulation of body fluid levels GO:0050878 90 0.014
regulation of protein maturation GO:1903317 50 0.014
response to oxygen levels GO:0070482 265 0.014
neuron projection development GO:0031175 273 0.014
regulation of phosphorus metabolic process GO:0051174 349 0.014
negative regulation of protein maturation GO:1903318 47 0.014
glycogen metabolic process GO:0005977 23 0.014
reactive oxygen species metabolic process GO:0072593 37 0.014
glycerol transport GO:0015793 2 0.014
female pregnancy GO:0007565 122 0.014
regulation of rna metabolic process GO:0051252 391 0.014
cytokine secretion GO:0050663 15 0.014
sexual reproduction GO:0019953 148 0.014
protein heterooligomerization GO:0051291 89 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.014
localization of cell GO:0051674 202 0.013
nucleic acid templated transcription GO:0097659 379 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
tonic smooth muscle contraction GO:0014820 4 0.013
calcium ion transport GO:0006816 131 0.013
phospholipase c activating serotonin receptor signaling pathway GO:0007208 2 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.013
single organism cellular localization GO:1902580 102 0.013
inflammatory response GO:0006954 150 0.013
central nervous system development GO:0007417 311 0.013
regulation of monooxygenase activity GO:0032768 8 0.013
regulation of establishment of protein localization GO:0070201 69 0.013
positive regulation of cell development GO:0010720 176 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
response to amino acid GO:0043200 75 0.013
gamete generation GO:0007276 124 0.013
actin filament based movement GO:0030048 16 0.013
receptor mediated endocytosis GO:0006898 42 0.013
platelet aggregation GO:0070527 4 0.013
steroid biosynthetic process GO:0006694 48 0.013
positive regulation of phosphate metabolic process GO:0045937 262 0.013
purine nucleotide catabolic process GO:0006195 136 0.013
regulation of transporter activity GO:0032409 50 0.013
regulation of platelet aggregation GO:0090330 1 0.012
protein phosphorylation GO:0006468 345 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.012
regulation of cellular amine metabolic process GO:0033238 8 0.012
limb morphogenesis GO:0035108 4 0.012
cellular response to hormone stimulus GO:0032870 247 0.012
nicotinamide nucleotide metabolic process GO:0046496 28 0.012
regulation of cellular amino acid metabolic process GO:0006521 2 0.012
cellular protein localization GO:0034613 122 0.012
regulation of skeletal muscle tissue growth GO:0048631 3 0.012
purine nucleoside triphosphate metabolic process GO:0009144 141 0.012
generation of precursor metabolites and energy GO:0006091 62 0.012
wound healing spreading of epidermal cells GO:0035313 2 0.012
response to lipopolysaccharide GO:0032496 191 0.012
ribonucleoside triphosphate catabolic process GO:0009203 122 0.012
positive regulation of ion transmembrane transport GO:0034767 24 0.012
ribose phosphate metabolic process GO:0019693 235 0.012
membrane organization GO:0061024 94 0.012
leukotriene biosynthetic process GO:0019370 3 0.012
cellular glucan metabolic process GO:0006073 23 0.012
protein complex assembly GO:0006461 263 0.012
purine containing compound biosynthetic process GO:0072522 85 0.012
regulation of tube size GO:0035150 89 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
negative regulation of molecular function GO:0044092 133 0.012
regulation of ion transmembrane transport GO:0034765 121 0.012
branching morphogenesis of an epithelial tube GO:0048754 14 0.012
energy reserve metabolic process GO:0006112 25 0.012
response to vitamin a GO:0033189 36 0.011
positive regulation of blood pressure by epinephrine norepinephrine GO:0003321 2 0.011
aromatic compound catabolic process GO:0019439 168 0.011
negative regulation of stress activated protein kinase signaling cascade GO:0070303 4 0.011
transformation of host cell by virus GO:0019087 4 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
cellular ketone metabolic process GO:0042180 51 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
positive regulation of cell communication GO:0010647 271 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
regulation of transmembrane transport GO:0034762 122 0.011
male gamete generation GO:0048232 99 0.011
positive regulation of response to wounding GO:1903036 34 0.011
positive regulation of cytoskeleton organization GO:0051495 26 0.011
nucleotide catabolic process GO:0009166 139 0.011
glucose homeostasis GO:0042593 75 0.011
organophosphate catabolic process GO:0046434 148 0.011
negative regulation of synaptic transmission glutamatergic GO:0051967 8 0.011
regulation of cytokine secretion GO:0050707 11 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
positive regulation of b cell mediated immunity GO:0002714 2 0.011
response to cold GO:0009409 29 0.011
lipid metabolic process GO:0006629 283 0.011
positive regulation of epidermis development GO:0045684 1 0.010
response to vitamin GO:0033273 131 0.010
anatomical structure formation involved in morphogenesis GO:0048646 83 0.010
positive regulation of saliva secretion GO:0046878 3 0.010
single organismal cell cell adhesion GO:0016337 42 0.010
synaptic transmission glutamatergic GO:0035249 33 0.010
neuron neuron synaptic transmission GO:0007270 60 0.010
positive regulation of isotype switching GO:0045830 1 0.010
response to insecticide GO:0017085 21 0.010
positive regulation of signaling GO:0023056 270 0.010
regulation of dopamine secretion GO:0014059 15 0.010
protein homooligomerization GO:0051260 91 0.010
cellular carbohydrate metabolic process GO:0044262 72 0.010
actin filament based process GO:0030029 86 0.010
positive regulation of skeletal muscle tissue growth GO:0048633 2 0.010
regulation of angiogenesis GO:0045765 39 0.010
nucleoside triphosphate catabolic process GO:0009143 123 0.010
positive regulation of transmembrane transport GO:0034764 25 0.010
response to hyperoxia GO:0055093 45 0.010
nucleobase containing small molecule metabolic process GO:0055086 316 0.010
regulation of cell projection organization GO:0031344 175 0.010
cellular response to glucose stimulus GO:0071333 65 0.010
positive regulation of smooth muscle cell migration GO:0014911 27 0.010
atp metabolic process GO:0046034 72 0.010
regulation of endocytosis GO:0030100 42 0.010
negative regulation of natural killer cell mediated immune response to tumor cell GO:0002856 1 0.010
tissue development GO:0009888 252 0.010

Cma1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.036
disease of anatomical entity DOID:7 0 0.036
respiratory system disease DOID:1579 0 0.015
lower respiratory tract disease DOID:0050161 0 0.015
central nervous system disease DOID:331 0 0.013
kidney disease DOID:557 0 0.012
urinary system disease DOID:18 0 0.012
musculoskeletal system disease DOID:17 0 0.011
connective tissue disease DOID:65 0 0.011
disease of metabolism DOID:0014667 0 0.011
acquired metabolic disease DOID:0060158 0 0.010