|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
387 |
0.471
|
Zebrafish |
|
|
head development
|
GO:0060322 |
247 |
0.469
|
Mouse Rat |
|
|
positive regulation of cell communication
|
GO:0010647 |
271 |
0.459
|
Mouse |
|
|
ion transmembrane transport
|
GO:0034220 |
365 |
0.406
|
|
|
|
muscle contraction
|
GO:0006936 |
88 |
0.404
|
|
|
|
cellular component movement
|
GO:0006928 |
248 |
0.358
|
Zebrafish Mouse |
|
|
locomotion
|
GO:0040011 |
237 |
0.357
|
Zebrafish Mouse |
|
|
central nervous system development
|
GO:0007417 |
311 |
0.322
|
Zebrafish Mouse Rat |
|
|
neurological system process
|
GO:0050877 |
219 |
0.310
|
Mouse Fly |
|
|
circulatory system process
|
GO:0003013 |
183 |
0.302
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
263 |
0.284
|
|
|
|
cell motility
|
GO:0048870 |
202 |
0.249
|
Zebrafish Mouse |
|
|
sensory perception
|
GO:0007600 |
101 |
0.232
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.232
|
|
|
|
potassium ion transport
|
GO:0006813 |
97 |
0.222
|
|
|
|
cation transport
|
GO:0006812 |
382 |
0.221
|
|
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
197 |
0.221
|
|
|
|
positive regulation of intracellular signal transduction
|
GO:1902533 |
138 |
0.204
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
172 |
0.202
|
|
|
|
behavior
|
GO:0007610 |
205 |
0.200
|
Mouse |
|
|
chemical homeostasis
|
GO:0048878 |
292 |
0.187
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
229 |
0.187
|
|
|
|
cell cell signaling
|
GO:0007267 |
335 |
0.184
|
Mouse |
|
|
positive regulation of response to stimulus
|
GO:0048584 |
285 |
0.182
|
Mouse |
|
|
response to hypoxia
|
GO:0001666 |
231 |
0.180
|
|
|
|
sensory organ development
|
GO:0007423 |
74 |
0.171
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
167 |
0.164
|
|
|
|
blood circulation
|
GO:0008015 |
183 |
0.162
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
202 |
0.161
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
359 |
0.155
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
229 |
0.153
|
|
|
|
growth
|
GO:0040007 |
165 |
0.149
|
Zebrafish |
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
295 |
0.147
|
|
|
|
brain development
|
GO:0007420 |
247 |
0.140
|
Mouse Rat |
|
|
regulation of membrane potential
|
GO:0042391 |
110 |
0.138
|
Mouse Fly |
|
|
positive regulation of transport
|
GO:0051050 |
245 |
0.137
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
314 |
0.137
|
|
|
|
immune system process
|
GO:0002376 |
204 |
0.136
|
|
|
|
striated muscle contraction
|
GO:0006941 |
44 |
0.133
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
202 |
0.133
|
|
|
|
response to bacterium
|
GO:0009617 |
200 |
0.133
|
|
|
|
learning or memory
|
GO:0007611 |
90 |
0.126
|
Mouse |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
377 |
0.126
|
|
|
|
sensory perception of pain
|
GO:0019233 |
73 |
0.126
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
208 |
0.125
|
Zebrafish Mouse |
|
|
regulation of ion transport
|
GO:0043269 |
245 |
0.124
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
125 |
0.119
|
Mouse |
|
|
chemotaxis
|
GO:0006935 |
66 |
0.116
|
Mouse |
|
|
regulation of cell development
|
GO:0060284 |
263 |
0.115
|
Zebrafish Mouse |
|
|
cognition
|
GO:0050890 |
92 |
0.113
|
Mouse |
|
|
homeostatic process
|
GO:0042592 |
331 |
0.111
|
|
|
|
anatomical structure morphogenesis
|
GO:0009653 |
298 |
0.108
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
165 |
0.106
|
Zebrafish |
|
|
response to inorganic substance
|
GO:0010035 |
377 |
0.104
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
319 |
0.104
|
|
|
|
response to oxidative stress
|
GO:0006979 |
186 |
0.100
|
|
|
|
regulation of system process
|
GO:0044057 |
208 |
0.099
|
|
|
|
regeneration
|
GO:0031099 |
163 |
0.099
|
Zebrafish |
|
|
regulation of multicellular organismal development
|
GO:2000026 |
376 |
0.099
|
Zebrafish Mouse |
|
|
positive regulation of locomotion
|
GO:0040017 |
102 |
0.098
|
|
|
|
cellular component biogenesis
|
GO:0044085 |
368 |
0.096
|
Fly |
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
334 |
0.094
|
|
|
|
positive regulation of long term synaptic potentiation
|
GO:1900273 |
4 |
0.093
|
|
|
|
rna biosynthetic process
|
GO:0032774 |
380 |
0.093
|
|
|
|
positive regulation of signaling
|
GO:0023056 |
270 |
0.093
|
Mouse |
|
|
response to metal ion
|
GO:0010038 |
253 |
0.093
|
|
|
|
single organism behavior
|
GO:0044708 |
130 |
0.092
|
Mouse |
|
|
positive regulation of gene expression
|
GO:0010628 |
244 |
0.092
|
Mouse |
|
|
metal ion homeostasis
|
GO:0055065 |
186 |
0.090
|
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
247 |
0.089
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
320 |
0.089
|
Zebrafish Mouse |
|
|
positive regulation of developmental process
|
GO:0051094 |
283 |
0.088
|
Zebrafish |
|
|
metal ion transport
|
GO:0030001 |
289 |
0.088
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
162 |
0.087
|
|
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
380 |
0.087
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
349 |
0.086
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
319 |
0.086
|
|
|
|
regulation of membrane repolarization
|
GO:0060306 |
1 |
0.086
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
89 |
0.085
|
|
|
|
heart process
|
GO:0003015 |
57 |
0.085
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
162 |
0.085
|
|
|
|
ion homeostasis
|
GO:0050801 |
212 |
0.084
|
|
|
|
serotonin receptor signaling pathway
|
GO:0007210 |
10 |
0.083
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
242 |
0.082
|
Mouse |
|
|
secretion
|
GO:0046903 |
307 |
0.082
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
247 |
0.082
|
|
|
|
amine transport
|
GO:0015837 |
57 |
0.079
|
|
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
262 |
0.078
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
210 |
0.076
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
184 |
0.076
|
|
|
|
tube development
|
GO:0035295 |
89 |
0.076
|
|
|
|
localization of cell
|
GO:0051674 |
202 |
0.076
|
Zebrafish Mouse |
|
|
regulation of rna metabolic process
|
GO:0051252 |
391 |
0.075
|
|
|
|
tissue development
|
GO:0009888 |
252 |
0.075
|
|
|
|
muscle system process
|
GO:0003012 |
115 |
0.074
|
|
|
|
regulation of molecular function
|
GO:0065009 |
398 |
0.074
|
|
|
|
nucleic acid templated transcription
|
GO:0097659 |
379 |
0.074
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
386 |
0.073
|
|
|
|
organophosphate metabolic process
|
GO:0019637 |
370 |
0.072
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
67 |
0.072
|
|
|
|
macromolecular complex assembly
|
GO:0065003 |
273 |
0.071
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
237 |
0.071
|
|
|
|
cellular response to peptide
|
GO:1901653 |
133 |
0.071
|
|
|
|
protein oligomerization
|
GO:0051259 |
191 |
0.071
|
|
|
|
regulation of phosphorylation
|
GO:0042325 |
248 |
0.069
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
316 |
0.068
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
197 |
0.068
|
|
|
|
circadian rhythm
|
GO:0007623 |
88 |
0.068
|
|
|
|
cellular response to stress
|
GO:0033554 |
269 |
0.068
|
Zebrafish |
|
|
reproduction
|
GO:0000003 |
245 |
0.068
|
|
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
197 |
0.067
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
247 |
0.067
|
Zebrafish Mouse |
|
|
organic hydroxy compound transport
|
GO:0015850 |
77 |
0.067
|
|
|
|
macromolecular complex subunit organization
|
GO:0043933 |
339 |
0.066
|
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
252 |
0.066
|
|
|
|
transcription dna templated
|
GO:0006351 |
377 |
0.065
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
187 |
0.065
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter
|
GO:0045944 |
148 |
0.064
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
247 |
0.064
|
|
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
93 |
0.064
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
120 |
0.063
|
|
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
203 |
0.063
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
233 |
0.063
|
|
|
|
cell migration
|
GO:0016477 |
197 |
0.062
|
Zebrafish Mouse |
|
|
cell projection organization
|
GO:0030030 |
302 |
0.062
|
|
|
|
catabolic process
|
GO:0009056 |
351 |
0.061
|
|
|
|
regulation of transcription dna templated
|
GO:0006355 |
374 |
0.061
|
|
|
|
camp metabolic process
|
GO:0046058 |
63 |
0.061
|
|
|
|
response to wounding
|
GO:0009611 |
254 |
0.061
|
Zebrafish |
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
165 |
0.061
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
71 |
0.060
|
|
|
|
single organism biosynthetic process
|
GO:0044711 |
342 |
0.060
|
|
|
|
regulation of cell migration
|
GO:0030334 |
128 |
0.059
|
|
|
|
protein phosphorylation
|
GO:0006468 |
345 |
0.058
|
|
|
|
lipid metabolic process
|
GO:0006629 |
283 |
0.058
|
|
|
|
cellular response to lipid
|
GO:0071396 |
201 |
0.058
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
231 |
0.058
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
150 |
0.056
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
89 |
0.056
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
120 |
0.055
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
51 |
0.055
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
122 |
0.055
|
|
|
|
negative regulation of metabolic process
|
GO:0009892 |
331 |
0.054
|
|
|
|
rhythmic process
|
GO:0048511 |
156 |
0.054
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
110 |
0.054
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
107 |
0.054
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
140 |
0.054
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
27 |
0.053
|
|
|
|
response to oxygen levels
|
GO:0070482 |
265 |
0.053
|
|
|
|
positive regulation of phosphate metabolic process
|
GO:0045937 |
262 |
0.053
|
|
|
|
response to alkaloid
|
GO:0043279 |
132 |
0.053
|
|
|
|
gland development
|
GO:0048732 |
155 |
0.052
|
|
|
|
protein complex biogenesis
|
GO:0070271 |
263 |
0.052
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
279 |
0.051
|
|
|
|
synaptic transmission
|
GO:0007268 |
235 |
0.050
|
Mouse |
|
|
heart contraction
|
GO:0060047 |
57 |
0.050
|
|
|
|
positive regulation of amine transport
|
GO:0051954 |
26 |
0.050
|
|
|
|
protein complex subunit organization
|
GO:0071822 |
302 |
0.050
|
|
|
|
renal system development
|
GO:0072001 |
67 |
0.050
|
|
|
|
taxis
|
GO:0042330 |
67 |
0.050
|
Mouse |
|
|
regulation of cellular localization
|
GO:0060341 |
263 |
0.049
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
140 |
0.049
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
217 |
0.049
|
Zebrafish |
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
218 |
0.049
|
|
|
|
cellular potassium ion transport
|
GO:0071804 |
72 |
0.049
|
|
|
|
prostate gland epithelium morphogenesis
|
GO:0060740 |
2 |
0.049
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
158 |
0.048
|
|
|
|
multicellular organism growth
|
GO:0035264 |
1 |
0.048
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
264 |
0.048
|
Zebrafish Mouse |
|
|
sexual reproduction
|
GO:0019953 |
148 |
0.048
|
|
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
61 |
0.047
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
124 |
0.046
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
53 |
0.046
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
13 |
0.045
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
46 |
0.045
|
|
|
|
action potential
|
GO:0001508 |
54 |
0.045
|
Mouse Fly |
|
|
urinary bladder smooth muscle contraction
|
GO:0014832 |
4 |
0.044
|
|
|
|
protein heterooligomerization
|
GO:0051291 |
89 |
0.044
|
|
|
|
cytoskeleton organization
|
GO:0007010 |
111 |
0.044
|
Mouse |
|
|
regulation of cell motility
|
GO:2000145 |
131 |
0.044
|
|
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
197 |
0.043
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.043
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
61 |
0.043
|
|
|
|
musculoskeletal movement
|
GO:0050881 |
17 |
0.043
|
|
|
|
mapk cascade
|
GO:0000165 |
140 |
0.043
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
99 |
0.043
|
Mouse |
|
|
regulation of tube size
|
GO:0035150 |
89 |
0.042
|
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
381 |
0.042
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
106 |
0.042
|
|
|
|
response to hexose
|
GO:0009746 |
144 |
0.042
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
118 |
0.042
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
128 |
0.042
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
121 |
0.042
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
208 |
0.042
|
|
|
|
sodium ion transport
|
GO:0006814 |
82 |
0.042
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
304 |
0.041
|
|
|
|
membrane organization
|
GO:0061024 |
94 |
0.041
|
Human Mouse |
|
|
cellular cation homeostasis
|
GO:0030003 |
180 |
0.041
|
|
|
|
protein complex assembly
|
GO:0006461 |
263 |
0.041
|
|
|
|
urogenital system development
|
GO:0001655 |
78 |
0.040
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
123 |
0.040
|
|
|
|
neuron development
|
GO:0048666 |
286 |
0.040
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
175 |
0.039
|
Mouse |
|
|
motor neuron axon guidance
|
GO:0008045 |
1 |
0.039
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
94 |
0.039
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
48 |
0.039
|
|
|
|
regulation of locomotion
|
GO:0040012 |
148 |
0.039
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
117 |
0.039
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
117 |
0.038
|
|
|
|
ossification
|
GO:0001503 |
70 |
0.038
|
|
|
|
reproductive process
|
GO:0022414 |
372 |
0.038
|
|
|
|
membrane repolarization
|
GO:0086009 |
1 |
0.038
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
96 |
0.038
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
51 |
0.038
|
|
|
|
neuron projection guidance
|
GO:0097485 |
24 |
0.038
|
Mouse |
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
160 |
0.038
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
24 |
0.038
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
135 |
0.037
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
135 |
0.037
|
Zebrafish Mouse |
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
349 |
0.037
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
162 |
0.037
|
|
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
167 |
0.037
|
|
|
|
regulation of behavior
|
GO:0050795 |
61 |
0.037
|
|
|
|
telencephalon development
|
GO:0021537 |
62 |
0.036
|
Mouse |
|
|
response to peptide hormone
|
GO:0043434 |
278 |
0.036
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
75 |
0.036
|
|
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
346 |
0.036
|
|
|
|
cellular homeostasis
|
GO:0019725 |
252 |
0.036
|
|
|
|
eye development
|
GO:0001654 |
50 |
0.035
|
|
|
|
response to peptide
|
GO:1901652 |
292 |
0.035
|
|
|
|
actin filament based process
|
GO:0030029 |
86 |
0.035
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
83 |
0.034
|
|
|
|
regulation of amine transport
|
GO:0051952 |
54 |
0.034
|
|
|
|
regulation of secretion
|
GO:0051046 |
224 |
0.034
|
|
|
|
positive regulation of action potential
|
GO:0045760 |
8 |
0.034
|
|
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
178 |
0.034
|
Mouse |
|
|
intracellular transport
|
GO:0046907 |
185 |
0.034
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
172 |
0.034
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
122 |
0.034
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
51 |
0.033
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
143 |
0.033
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
176 |
0.033
|
Zebrafish |
|
|
skeletal system development
|
GO:0001501 |
41 |
0.033
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
194 |
0.033
|
|
|
|
regulation of response to stress
|
GO:0080134 |
126 |
0.032
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
31 |
0.032
|
|
|
|
cell adhesion
|
GO:0007155 |
110 |
0.032
|
|
|
|
neuron differentiation
|
GO:0030182 |
368 |
0.032
|
|
|
|
developmental growth
|
GO:0048589 |
100 |
0.032
|
Zebrafish |
|
|
response to axon injury
|
GO:0048678 |
59 |
0.032
|
Zebrafish |
|
|
negative regulation of signaling
|
GO:0023057 |
157 |
0.032
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
83 |
0.032
|
|
|
|
regulation of signal transduction
|
GO:0009966 |
318 |
0.032
|
Mouse |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
42 |
0.031
|
|
|
|
regulation of immune system process
|
GO:0002682 |
123 |
0.031
|
|
|
|
regulation of neuron death
|
GO:1901214 |
115 |
0.031
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
380 |
0.031
|
|
|
|
response to estradiol
|
GO:0032355 |
164 |
0.031
|
|
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
234 |
0.031
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
102 |
0.031
|
|
|
|
organ morphogenesis
|
GO:0009887 |
75 |
0.031
|
Fly |
|
|
regulation of striated muscle contraction
|
GO:0006942 |
21 |
0.031
|
|
|
|
response to corticosteroid
|
GO:0031960 |
235 |
0.031
|
|
|
|
rna metabolic process
|
GO:0016070 |
406 |
0.031
|
|
|
|
urinary tract smooth muscle contraction
|
GO:0014848 |
4 |
0.031
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
148 |
0.031
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
58 |
0.031
|
|
|
|
positive regulation of blood pressure by epinephrine norepinephrine
|
GO:0003321 |
2 |
0.030
|
|
|
|
secretion by cell
|
GO:0032940 |
248 |
0.030
|
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
28 |
0.030
|
|
|
|
adenylate cyclase inhibiting g protein coupled receptor signaling pathway
|
GO:0007193 |
19 |
0.030
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
229 |
0.030
|
|
|
|
neuronal action potential
|
GO:0019228 |
35 |
0.030
|
Mouse Fly |
|
|
negative regulation of transcription dna templated
|
GO:0045892 |
116 |
0.030
|
|
|
|
response to calcium ion
|
GO:0051592 |
59 |
0.030
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
138 |
0.030
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
79 |
0.030
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
249 |
0.030
|
|
|
|
kidney development
|
GO:0001822 |
67 |
0.030
|
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
260 |
0.030
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
36 |
0.030
|
|
|
|
protein tetramerization
|
GO:0051262 |
38 |
0.029
|
|
|
|
mesoderm development
|
GO:0007498 |
2 |
0.029
|
|
|
|
response to nutrient levels
|
GO:0031667 |
370 |
0.029
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
88 |
0.029
|
|
|
|
signal release
|
GO:0023061 |
145 |
0.029
|
|
|
|
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
|
GO:0014808 |
4 |
0.029
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
179 |
0.029
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
143 |
0.029
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
126 |
0.029
|
|
|
|
cellular response to metal ion
|
GO:0071248 |
55 |
0.028
|
|
|
|
response to nutrient
|
GO:0007584 |
248 |
0.028
|
|
|
|
neuromuscular process
|
GO:0050905 |
2 |
0.028
|
|
|
|
single organism organelle organization
|
GO:1902589 |
180 |
0.028
|
Mouse |
|
|
organelle organization
|
GO:0006996 |
266 |
0.028
|
Mouse |
|
|
positive regulation of saliva secretion
|
GO:0046878 |
3 |
0.028
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
177 |
0.028
|
|
|
|
negative regulation of transport
|
GO:0051051 |
136 |
0.028
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
283 |
0.028
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
99 |
0.028
|
Zebrafish |
|
|
response to monosaccharide
|
GO:0034284 |
159 |
0.028
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
84 |
0.027
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
132 |
0.027
|
|
|
|
regulation of systemic arterial blood pressure by norepinephrine epinephrine
|
GO:0001993 |
2 |
0.027
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
17 |
0.027
|
|
|
|
single organism catabolic process
|
GO:0044712 |
283 |
0.027
|
|
|
|
aging
|
GO:0007568 |
241 |
0.026
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
115 |
0.026
|
|
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
37 |
0.026
|
|
|
|
hormone metabolic process
|
GO:0042445 |
69 |
0.026
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
203 |
0.026
|
Mouse |
|
|
response to mechanical stimulus
|
GO:0009612 |
134 |
0.026
|
|
|
|
response to fungicide
|
GO:0060992 |
20 |
0.025
|
|
|
|
choline transport
|
GO:0015871 |
4 |
0.025
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
49 |
0.025
|
|
|
|
negative regulation of uterine smooth muscle contraction
|
GO:0070473 |
2 |
0.025
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
235 |
0.025
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
155 |
0.025
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
262 |
0.025
|
|
|
|
regulation of protein phosphorylation
|
GO:0001932 |
183 |
0.025
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
116 |
0.025
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
107 |
0.025
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
253 |
0.025
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
70 |
0.025
|
Mouse |
|
|
synapse organization
|
GO:0050808 |
46 |
0.025
|
|
|
|
negative regulation of circadian sleep wake cycle sleep
|
GO:0042321 |
5 |
0.025
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
233 |
0.025
|
|
|
|
organic substance catabolic process
|
GO:1901575 |
316 |
0.025
|
|
|
|
regulation of phosphatidylinositol dephosphorylation
|
GO:0060304 |
1 |
0.024
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
229 |
0.024
|
|
|
|
metanephric s shaped body morphogenesis
|
GO:0072284 |
2 |
0.024
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
51 |
0.024
|
|
|
|
sex differentiation
|
GO:0007548 |
113 |
0.024
|
|
|
|
cellular protein localization
|
GO:0034613 |
122 |
0.024
|
Mouse |
|
|
wound healing
|
GO:0042060 |
122 |
0.024
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
29 |
0.024
|
|
|
|
heart development
|
GO:0007507 |
72 |
0.024
|
Fly |
|
|
multicellular organismal response to stress
|
GO:0033555 |
25 |
0.024
|
|
|
|
response to carbohydrate
|
GO:0009743 |
183 |
0.024
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
91 |
0.024
|
|
|
|
regulation of long term synaptic potentiation
|
GO:1900271 |
5 |
0.024
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
227 |
0.024
|
|
|
|
cell fate determination
|
GO:0001709 |
2 |
0.024
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
50 |
0.024
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
281 |
0.023
|
|
|
|
limb morphogenesis
|
GO:0035108 |
4 |
0.023
|
|
|
|
dopamine secretion
|
GO:0014046 |
15 |
0.023
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
134 |
0.023
|
|
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
123 |
0.023
|
|
|
|
cellular macromolecule localization
|
GO:0070727 |
122 |
0.023
|
Mouse |
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
55 |
0.023
|
|
|
|
programmed cell death
|
GO:0012501 |
392 |
0.023
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
83 |
0.023
|
|
|
|
cellular catabolic process
|
GO:0044248 |
295 |
0.023
|
|
|
|
gastrulation
|
GO:0007369 |
2 |
0.023
|
|
|
|
gonad development
|
GO:0008406 |
104 |
0.022
|
|
|
|
forebrain development
|
GO:0030900 |
98 |
0.022
|
Mouse |
|
|
appendage morphogenesis
|
GO:0035107 |
4 |
0.022
|
|
|
|
cell communication involved in cardiac conduction
|
GO:0086065 |
2 |
0.022
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
43 |
0.022
|
|
|
|
macromolecule localization
|
GO:0033036 |
252 |
0.022
|
Mouse |
|
|
cardiac chamber development
|
GO:0003205 |
1 |
0.022
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
96 |
0.022
|
|
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
17 |
0.022
|
|
|
|
limbic system development
|
GO:0021761 |
38 |
0.022
|
|
|
|
negative regulation of circadian rhythm
|
GO:0042754 |
5 |
0.022
|
|
|
|
eye morphogenesis
|
GO:0048592 |
4 |
0.022
|
|
|
|
response to toxic substance
|
GO:0009636 |
133 |
0.022
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
79 |
0.022
|
Mouse |
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
124 |
0.022
|
|
|
|
s shaped body morphogenesis
|
GO:0072050 |
2 |
0.021
|
|
|
|
neuron death
|
GO:0070997 |
127 |
0.021
|
|
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
161 |
0.021
|
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
168 |
0.021
|
|
|
|
response to transition metal nanoparticle
|
GO:1990267 |
122 |
0.021
|
|
|
|
response to ammonium ion
|
GO:0060359 |
71 |
0.021
|
|
|
|
locomotory behavior
|
GO:0007626 |
15 |
0.021
|
Mouse |
|
|
acid secretion
|
GO:0046717 |
48 |
0.021
|
|
|
|
response to glucose
|
GO:0009749 |
136 |
0.021
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
48 |
0.021
|
|
|
|
response to growth factor
|
GO:0070848 |
189 |
0.021
|
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
27 |
0.021
|
|
|
|
multicellular organismal movement
|
GO:0050879 |
17 |
0.020
|
|
|
|
response to light stimulus
|
GO:0009416 |
52 |
0.020
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
1 |
0.020
|
|
|
|
regulation of catecholamine secretion
|
GO:0050433 |
32 |
0.020
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
9 |
0.020
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
341 |
0.020
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
38 |
0.020
|
|
|
|
anion transport
|
GO:0006820 |
178 |
0.020
|
|
|
|
olfactory learning
|
GO:0008355 |
1 |
0.020
|
|
|
|
regulation of protein modification process
|
GO:0031399 |
194 |
0.020
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
35 |
0.020
|
|
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
161 |
0.020
|
|
|
|
neuron neuron synaptic transmission
|
GO:0007270 |
60 |
0.020
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
133 |
0.020
|
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
155 |
0.020
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
105 |
0.020
|
|
|
|
negative regulation of rna biosynthetic process
|
GO:1902679 |
118 |
0.020
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
85 |
0.020
|
|
|
|
coronary vasculature morphogenesis
|
GO:0060977 |
3 |
0.020
|
|
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
153 |
0.019
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
33 |
0.019
|
Zebrafish |
|
|
catecholamine transport
|
GO:0051937 |
37 |
0.019
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
85 |
0.019
|
|
|
|
response to acid chemical
|
GO:0001101 |
222 |
0.019
|
|
|
|
hormone transport
|
GO:0009914 |
121 |
0.019
|
|
|
|
leukocyte migration
|
GO:0050900 |
38 |
0.019
|
|
|
|
startle response
|
GO:0001964 |
2 |
0.019
|
|
|
|
olfactory behavior
|
GO:0042048 |
2 |
0.018
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
77 |
0.018
|
|
|
|
skeletal muscle contraction
|
GO:0003009 |
17 |
0.018
|
|
|
|
neurological system process involved in regulation of systemic arterial blood pressure
|
GO:0001976 |
3 |
0.018
|
|
|
|
negative regulation of macromolecule biosynthetic process
|
GO:0010558 |
148 |
0.018
|
|
|
|
neuromuscular synaptic transmission
|
GO:0007274 |
2 |
0.018
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
115 |
0.018
|
|
|
|
chemosensory behavior
|
GO:0007635 |
2 |
0.018
|
|
|
|
synaptic transmission gabaergic
|
GO:0051932 |
22 |
0.018
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
182 |
0.018
|
|
|
|
digestive system development
|
GO:0055123 |
41 |
0.018
|
|
|
|
fat cell proliferation
|
GO:0070341 |
2 |
0.018
|
|
|
|
negative regulation of nucleic acid templated transcription
|
GO:1903507 |
117 |
0.018
|
|
|
|
regulation of cation channel activity
|
GO:2001257 |
23 |
0.017
|
|
|
|
associative learning
|
GO:0008306 |
19 |
0.017
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
38 |
0.017
|
|
|
|
n methyl d aspartate receptor clustering
|
GO:0097114 |
2 |
0.017
|
|
|
|
reproductive system development
|
GO:0061458 |
128 |
0.017
|
|
|
|
regulation of smooth muscle contraction
|
GO:0006940 |
29 |
0.017
|
|
|
|
mechanoreceptor differentiation
|
GO:0042490 |
2 |
0.017
|
|
|
|
negative regulation of gene expression
|
GO:0010629 |
199 |
0.017
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
90 |
0.017
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
122 |
0.017
|
|
|
|
oxoacid metabolic process
|
GO:0043436 |
290 |
0.017
|
|
|
|
response to nicotine
|
GO:0035094 |
51 |
0.017
|
|
|
|
positive regulation of molecular function
|
GO:0044093 |
230 |
0.017
|
|
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
2 |
0.016
|
|
|
|
positive regulation of catalytic activity
|
GO:0043085 |
184 |
0.016
|
|
|
|
response to cgmp
|
GO:0070305 |
3 |
0.016
|
|
|
|
single organism reproductive process
|
GO:0044702 |
297 |
0.016
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
77 |
0.016
|
|
|
|
female sex differentiation
|
GO:0046660 |
59 |
0.016
|
|
|
|
sodium ion transmembrane transport
|
GO:0035725 |
67 |
0.016
|
|
|
|
regulation of saliva secretion
|
GO:0046877 |
3 |
0.016
|
|
|
|
neuron projection development
|
GO:0031175 |
273 |
0.016
|
|
|
|
developmental induction
|
GO:0031128 |
2 |
0.016
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
200 |
0.016
|
Zebrafish |
|
|
negative regulation of cellular macromolecule biosynthetic process
|
GO:2000113 |
141 |
0.016
|
|
|
|
calcium ion transport
|
GO:0006816 |
131 |
0.016
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
191 |
0.016
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
72 |
0.016
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
142 |
0.016
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
21 |
0.016
|
|
|
|
response to fatty acid
|
GO:0070542 |
65 |
0.016
|
|
|
|
positive regulation of dopamine secretion
|
GO:0033603 |
8 |
0.015
|
|
|
|
monoamine transport
|
GO:0015844 |
43 |
0.015
|
|
|
|
cartilage development
|
GO:0051216 |
22 |
0.015
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
335 |
0.015
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
45 |
0.015
|
|
|
|
cardiovascular system development
|
GO:0072358 |
134 |
0.015
|
Fly |
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
267 |
0.015
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
85 |
0.015
|
|
|
|
male sex differentiation
|
GO:0046661 |
64 |
0.015
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
47 |
0.015
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
81 |
0.015
|
|
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
75 |
0.015
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.015
|
|
|
|
cation homeostasis
|
GO:0055080 |
195 |
0.015
|
|
|
|
apoptotic process
|
GO:0006915 |
381 |
0.015
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
84 |
0.015
|
|
|
|
membrane depolarization during action potential
|
GO:0086010 |
1 |
0.015
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
181 |
0.015
|
Mouse |
|
|
respiratory gaseous exchange
|
GO:0007585 |
4 |
0.014
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
175 |
0.014
|
Zebrafish Mouse |
|
|
negative regulation of neurogenesis
|
GO:0050768 |
78 |
0.014
|
Mouse |
|
|
female pregnancy
|
GO:0007565 |
122 |
0.014
|
|
|
|
membrane depolarization
|
GO:0051899 |
32 |
0.014
|
|
|
|
intracellular protein transport
|
GO:0006886 |
79 |
0.014
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
140 |
0.014
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
123 |
0.014
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
114 |
0.014
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
90 |
0.014
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
208 |
0.014
|
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
289 |
0.014
|
Mouse |
|
|
cellular response to oxygen levels
|
GO:0071453 |
60 |
0.014
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
49 |
0.014
|
|
|
|
regulation of potassium ion transport
|
GO:0043266 |
29 |
0.014
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
10 |
0.014
|
|
|
|
catecholamine secretion
|
GO:0050432 |
33 |
0.014
|
|
|
|
positive regulation of growth
|
GO:0045927 |
55 |
0.014
|
Zebrafish |
|
|
regulation of defecation
|
GO:2000292 |
1 |
0.014
|
|
|
|
synaptic transmission cholinergic
|
GO:0007271 |
11 |
0.014
|
|
|
|
regulation of growth
|
GO:0040008 |
105 |
0.014
|
Zebrafish |
|
|
regulation of feeding behavior
|
GO:0060259 |
14 |
0.014
|
|
