Rattus norvegicus

0 known processes

Col4a2

collagen, type IV, alpha 2

Col4a2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to growth factor GO:0070848 189 0.421
cellular response to endogenous stimulus GO:0071495 377 0.303
response to extracellular stimulus GO:0009991 380 0.169
response to acid chemical GO:0001101 222 0.163
response to oxygen levels GO:0070482 265 0.160
response to fluoride GO:1902617 3 0.148
response to mechanical stimulus GO:0009612 134 0.145
cellular response to organic cyclic compound GO:0071407 202 0.139
tissue development GO:0009888 252 0.134
Rat Fly
positive regulation of transport GO:0051050 245 0.134
single organism biosynthetic process GO:0044711 342 0.119
response to ionizing radiation GO:0010212 59 0.117
cellular response to mechanical stimulus GO:0071260 48 0.114
response to hydrogen peroxide GO:0042542 89 0.111
cellular response to growth factor stimulus GO:0071363 162 0.111
macromolecule localization GO:0033036 252 0.107
cellular response to oxygen containing compound GO:1901701 386 0.103
protein complex assembly GO:0006461 263 0.099
response to nutrient levels GO:0031667 370 0.098
response to inorganic substance GO:0010035 377 0.091
cellular response to nicotine GO:0071316 7 0.089
response to tumor necrosis factor GO:0034612 56 0.085
response to carbohydrate GO:0009743 183 0.085
cellular component biogenesis GO:0044085 368 0.084
response to wounding GO:0009611 254 0.084
carboxylic acid metabolic process GO:0019752 289 0.079
regulation of cell motility GO:2000145 131 0.077
response to oxidative stress GO:0006979 186 0.073
protein localization GO:0008104 191 0.069
response to nutrient GO:0007584 248 0.067
programmed cell death GO:0012501 392 0.065
regulation of cellular protein metabolic process GO:0032268 267 0.065
intracellular signal transduction GO:0035556 314 0.063
regulation of cellular component organization GO:0051128 368 0.063
response to estradiol GO:0032355 164 0.062
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.058
regulation of anatomical structure morphogenesis GO:0022603 141 0.058
response to glucocorticoid GO:0051384 223 0.058
cellular response to abiotic stimulus GO:0071214 85 0.057
macromolecular complex assembly GO:0065003 273 0.056
response to amino acid GO:0043200 75 0.056
positive regulation of cell communication GO:0010647 271 0.056
membrane organization GO:0061024 94 0.055
forebrain development GO:0030900 98 0.053
oxoacid metabolic process GO:0043436 290 0.053
response to cytokine GO:0034097 215 0.052
positive regulation of stem cell differentiation GO:2000738 2 0.051
organophosphate metabolic process GO:0019637 370 0.051
epithelial cell differentiation GO:0030855 71 0.051
Rat
regulation of signal transduction GO:0009966 318 0.050
apoptotic process GO:0006915 381 0.050
response to temperature stimulus GO:0009266 94 0.048
multi multicellular organism process GO:0044706 138 0.048
protein heterooligomerization GO:0051291 89 0.047
muscle organ development GO:0007517 50 0.046
Fly
response to estrogen GO:0043627 232 0.045
positive regulation of response to stimulus GO:0048584 285 0.045
regulation of cellular component movement GO:0051270 150 0.044
response to corticosteroid GO:0031960 235 0.044
response to x ray GO:0010165 15 0.044
single organism membrane organization GO:0044802 74 0.043
negative regulation of multicellular organismal process GO:0051241 203 0.043
regulation of cell development GO:0060284 263 0.043
response to metal ion GO:0010038 253 0.043
cell junction organization GO:0034330 21 0.042
cellular macromolecule localization GO:0070727 122 0.042
cell matrix adhesion GO:0007160 19 0.041
organic acid metabolic process GO:0006082 292 0.041
amine metabolic process GO:0009308 38 0.040
wound healing GO:0042060 122 0.040
small gtpase mediated signal transduction GO:0007264 36 0.039
cellular response to hormone stimulus GO:0032870 247 0.039
response to reactive oxygen species GO:0000302 120 0.038
aging GO:0007568 241 0.037
response to camp GO:0051591 91 0.037
cellular response to corticosteroid stimulus GO:0071384 69 0.037
regulation of apoptotic process GO:0042981 335 0.036
cellular response to glucocorticoid stimulus GO:0071385 68 0.036
regulation of protein metabolic process GO:0051246 289 0.036
endomembrane system organization GO:0010256 48 0.036
positive regulation of signaling GO:0023056 270 0.035
nucleotide metabolic process GO:0009117 279 0.035
protein oligomerization GO:0051259 191 0.035
cellular component movement GO:0006928 248 0.035
response to alkaloid GO:0043279 132 0.035
cellular amine metabolic process GO:0044106 38 0.034
cell cell signaling GO:0007267 335 0.034
positive regulation of cellular component organization GO:0051130 200 0.033
response to transforming growth factor beta GO:0071559 46 0.033
striated muscle tissue development GO:0014706 58 0.033
Fly
protein complex subunit organization GO:0071822 302 0.032
positive regulation of signal transduction GO:0009967 175 0.032
head development GO:0060322 247 0.032
regulation of programmed cell death GO:0043067 341 0.032
neurological system process GO:0050877 219 0.032
response to peptide GO:1901652 292 0.031
response to monosaccharide GO:0034284 159 0.031
cellular response to organonitrogen compound GO:0071417 197 0.031
cellular ketone metabolic process GO:0042180 51 0.031
positive regulation of protein metabolic process GO:0051247 178 0.031
positive regulation of behavior GO:0048520 38 0.031
sensory perception GO:0007600 101 0.031
regulation of system process GO:0044057 208 0.030
regulation of secretion by cell GO:1903530 208 0.030
formation of primary germ layer GO:0001704 1 0.030
positive regulation of cellular amine metabolic process GO:0033240 3 0.030
transmembrane transport GO:0055085 412 0.029
cellular component assembly GO:0022607 360 0.029
endochondral bone growth GO:0003416 3 0.029
positive regulation of multicellular organismal process GO:0051240 387 0.029
skeletal muscle tissue development GO:0007519 31 0.028
Fly
anatomical structure formation involved in morphogenesis GO:0048646 83 0.028
regulation of phosphorylation GO:0042325 248 0.028
positive regulation of protein phosphorylation GO:0001934 135 0.027
brain development GO:0007420 247 0.027
gastrulation GO:0007369 2 0.027
regulation of cellular ketone metabolic process GO:0010565 27 0.027
blood vessel morphogenesis GO:0048514 58 0.027
bone development GO:0060348 25 0.027
ovulation cycle process GO:0022602 50 0.027
response to peptide hormone GO:0043434 278 0.026
positive regulation of apoptotic process GO:0043065 154 0.026
organic substance catabolic process GO:1901575 316 0.026
regulation of response to stress GO:0080134 126 0.026
reproductive process GO:0022414 372 0.026
negative regulation of cell development GO:0010721 82 0.026
chemical homeostasis GO:0048878 292 0.026
ras protein signal transduction GO:0007265 29 0.026
endochondral bone morphogenesis GO:0060350 7 0.025
multicellular organismal macromolecule metabolic process GO:0044259 21 0.025
cellular response to vitamin e GO:0071306 3 0.025
response to organophosphorus GO:0046683 102 0.025
divalent inorganic cation transport GO:0072511 134 0.024
regulation of synaptic transmission GO:0050804 141 0.024
growth plate cartilage development GO:0003417 2 0.024
cation transport GO:0006812 382 0.024
response to ketone GO:1901654 182 0.024
behavior GO:0007610 205 0.024
regulation of response to external stimulus GO:0032101 106 0.024
positive regulation of cell proliferation GO:0008284 249 0.024
cellular response to lipid GO:0071396 201 0.024
response to nicotine GO:0035094 51 0.024
positive regulation of biosynthetic process GO:0009891 319 0.023
muscle structure development GO:0061061 87 0.023
Fly
cellular amino acid metabolic process GO:0006520 107 0.023
regeneration GO:0031099 163 0.023
positive regulation of rna biosynthetic process GO:1902680 197 0.023
regulation of protein modification process GO:0031399 194 0.023
positive regulation of developmental process GO:0051094 283 0.023
regulation of cellular localization GO:0060341 263 0.023
cellular response to cytokine stimulus GO:0071345 127 0.023
response to vitamin GO:0033273 131 0.023
chylomicron remodeling GO:0034371 1 0.023
cellular response to nutrient GO:0031670 30 0.022
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.022
central nervous system development GO:0007417 311 0.022
defense response GO:0006952 194 0.022
isopeptide cross linking GO:0018262 1 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
protein complex biogenesis GO:0070271 263 0.022
single organism intracellular transport GO:1902582 166 0.022
response to calcium ion GO:0051592 59 0.021
ossification GO:0001503 70 0.021
macromolecular complex subunit organization GO:0043933 339 0.020
response to monoamine GO:0071867 17 0.020
developmental growth GO:0048589 100 0.020
growth GO:0040007 165 0.020
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
cellular protein localization GO:0034613 122 0.020
synaptic transmission GO:0007268 235 0.019
regulation of secretion GO:0051046 224 0.019
cellular response to extracellular stimulus GO:0031668 73 0.019
epiboly involved in wound healing GO:0090505 2 0.019
regulation of multicellular organismal development GO:2000026 376 0.019
divalent metal ion transport GO:0070838 132 0.019
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.019
response to lipopolysaccharide GO:0032496 191 0.019
lipid metabolic process GO:0006629 283 0.019
regulation of blood vessel size GO:0050880 89 0.019
divalent inorganic cation homeostasis GO:0072507 165 0.019
cation homeostasis GO:0055080 195 0.018
reproduction GO:0000003 245 0.018
vascular process in circulatory system GO:0003018 96 0.018
single organism catabolic process GO:0044712 283 0.018
positive regulation of angiogenesis GO:0045766 28 0.018
regulation of intracellular signal transduction GO:1902531 218 0.018
negative regulation of endothelial cell proliferation GO:0001937 5 0.018
regulation of cell morphogenesis GO:0022604 77 0.018
carbohydrate derivative metabolic process GO:1901135 346 0.018
cellular response to peptide hormone stimulus GO:0071375 120 0.018
dna metabolic process GO:0006259 96 0.018
negative regulation of cardiac muscle tissue development GO:0055026 3 0.018
ion transmembrane transport GO:0034220 365 0.018
positive regulation of cell motility GO:2000147 97 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.017
regulation of cell differentiation GO:0045595 320 0.017
salivary gland development GO:0007431 3 0.017
response to decreased oxygen levels GO:0036293 237 0.017
response to epidermal growth factor GO:0070849 18 0.017
female pregnancy GO:0007565 122 0.017
regulation of blood pressure GO:0008217 83 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
metal ion homeostasis GO:0055065 186 0.016
skeletal muscle tissue regeneration GO:0043403 10 0.016
positive regulation of cell death GO:0010942 184 0.016
cytosolic calcium ion homeostasis GO:0051480 140 0.016
immune system process GO:0002376 204 0.016
epithelium development GO:0060429 96 0.016
Rat Fly
regulation of behavior GO:0050795 61 0.016
cell adhesion GO:0007155 110 0.016
hormone secretion GO:0046879 115 0.016
response to dexamethasone GO:0071548 49 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
cellular homeostasis GO:0019725 252 0.016
catabolic process GO:0009056 351 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
sensory organ development GO:0007423 74 0.015
immune response GO:0006955 104 0.015
oxidation reduction process GO:0055114 304 0.015
regulation of epithelial to mesenchymal transition GO:0010717 2 0.015
single organism cellular localization GO:1902580 102 0.015
regulation of tight junction assembly GO:2000810 2 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
regulation of phosphate metabolic process GO:0019220 349 0.015
positive regulation of cell development GO:0010720 176 0.015
digestive tract development GO:0048565 39 0.015
Fly
skeletal system morphogenesis GO:0048705 12 0.015
protein transport GO:0015031 132 0.015
positive regulation of locomotion GO:0040017 102 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
regulation of peptide secretion GO:0002791 82 0.015
cellular response to steroid hormone stimulus GO:0071383 93 0.015
digestive system development GO:0055123 41 0.014
Fly
response to transition metal nanoparticle GO:1990267 122 0.014
rhythmic process GO:0048511 156 0.014
leukocyte activation GO:0045321 76 0.014
circulatory system process GO:0003013 183 0.014
localization of cell GO:0051674 202 0.014
icosanoid metabolic process GO:0006690 38 0.014
gap junction assembly GO:0016264 2 0.014
wound healing spreading of epidermal cells GO:0035313 2 0.014
positive regulation of phosphate metabolic process GO:0045937 262 0.014
regulation of membrane potential GO:0042391 110 0.014
response to purine containing compound GO:0014074 126 0.014
ion homeostasis GO:0050801 212 0.014
regulation of cell proliferation GO:0042127 359 0.014
response to l ascorbic acid GO:0033591 15 0.013
positive regulation of gene expression GO:0010628 244 0.013
intracellular transport GO:0046907 185 0.013
epiboly GO:0090504 2 0.013
response to glucose GO:0009749 136 0.013
regulation of dna metabolic process GO:0051052 60 0.013
defense response to gram negative bacterium GO:0050829 3 0.013
response to bacterium GO:0009617 200 0.013
regulation of hormone levels GO:0010817 187 0.013
peptide cross linking GO:0018149 1 0.013
positive regulation of protein modification process GO:0031401 142 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
mrna transcription from rna polymerase ii promoter GO:0042789 1 0.013
cellular response to stress GO:0033554 269 0.013
response to radiation GO:0009314 137 0.012
protein lipid complex remodeling GO:0034368 1 0.012
response to heat GO:0009408 60 0.012
response to other organism GO:0051707 220 0.012
muscle cell proliferation GO:0033002 84 0.012
developmental growth involved in morphogenesis GO:0060560 33 0.012
regulation of cell migration GO:0030334 128 0.012
positive regulation of endothelial cell migration GO:0010595 4 0.012
regulation of nervous system development GO:0051960 264 0.012
positive regulation of cellular component movement GO:0051272 102 0.012
positive regulation of mapk cascade GO:0043410 92 0.012
secretion by cell GO:0032940 248 0.012
regulation of endocytosis GO:0030100 42 0.012
syncytium formation by plasma membrane fusion GO:0000768 3 0.012
positive regulation of cell migration GO:0030335 96 0.012
cellular response to external stimulus GO:0071496 118 0.012
ribose phosphate metabolic process GO:0019693 235 0.012
rho protein signal transduction GO:0007266 11 0.012
anatomical structure morphogenesis GO:0009653 298 0.012
Fly
cellular response to peptide GO:1901653 133 0.012
positive regulation of nucleic acid templated transcription GO:1903508 197 0.012
wound healing spreading of cells GO:0044319 2 0.011
cation transmembrane transport GO:0098655 263 0.011
positive regulation of dna metabolic process GO:0051054 39 0.011
establishment of protein localization GO:0045184 141 0.011
skin morphogenesis GO:0043589 2 0.011
spindle organization GO:0007051 2 0.011
secretion GO:0046903 307 0.011
regulation of anatomical structure size GO:0090066 135 0.011
transforming growth factor beta receptor signaling pathway GO:0007179 18 0.011
glycolipid biosynthetic process GO:0009247 6 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
sensory perception of light stimulus GO:0050953 3 0.011
multicellular organism reproduction GO:0032504 233 0.011
organelle organization GO:0006996 266 0.011
muscle cell migration GO:0014812 36 0.011
regulation of embryonic development GO:0045995 2 0.011
bone morphogenesis GO:0060349 11 0.011
regulation of tube size GO:0035150 89 0.011
cell morphogenesis GO:0000902 142 0.011
regulation of cellular response to growth factor stimulus GO:0090287 15 0.011
cellular response to alkaloid GO:0071312 25 0.011
cellular response to nutrient levels GO:0031669 60 0.010
syncytium formation GO:0006949 4 0.010
response to hyperoxia GO:0055093 45 0.010
negative regulation of innate immune response GO:0045824 4 0.010
regulation of peptide hormone secretion GO:0090276 80 0.010
actin crosslink formation GO:0051764 3 0.010
cell communication involved in cardiac conduction GO:0086065 2 0.010
neuron projection development GO:0031175 273 0.010
response to fatty acid GO:0070542 65 0.010
activation of cysteine type endopeptidase activity GO:0097202 4 0.010
positive regulation of kinase activity GO:0033674 77 0.010

Col4a2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 0 0.163
disease of anatomical entity DOID:7 0 0.163
myopathy DOID:423 0 0.076
muscle tissue disease DOID:66 0 0.076
muscular dystrophy DOID:9884 0 0.076
muscular disease DOID:0080000 0 0.076
connective tissue disease DOID:65 0 0.049
nervous system disease DOID:863 0 0.018
sensory system disease DOID:0050155 0 0.018
bone disease DOID:0080001 0 0.011
kidney disease DOID:557 0 0.010
urinary system disease DOID:18 0 0.010