Rattus norvegicus

0 known processes

Col5a1

collagen, type V, alpha 1

Col5a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to fluoride GO:1902617 3 0.951
Rat
cellular response to nicotine GO:0071316 7 0.936
Rat
embryonic skeletal system development GO:0048706 3 0.935
cartilage development involved in endochondral bone morphogenesis GO:0060351 3 0.925
Rat
endochondral bone morphogenesis GO:0060350 7 0.883
Rat
artery development GO:0060840 3 0.806
tissue development GO:0009888 252 0.690
Human Rat
aorta development GO:0035904 2 0.632
connective tissue development GO:0061448 33 0.620
Rat
collagen fibril organization GO:0030199 1 0.617
Human
response to vitamin e GO:0033197 24 0.537
Rat
cellular response to fluoride GO:1902618 1 0.502
Rat
skeletal system development GO:0001501 41 0.460
Rat
cellular response to vitamin e GO:0071306 3 0.456
Rat
protein heterotrimerization GO:0070208 2 0.449
response to hyperoxia GO:0055093 45 0.390
Rat
growth plate cartilage development GO:0003417 2 0.368
Rat
cellular response to tumor necrosis factor GO:0071356 46 0.368
Rat
response to tumor necrosis factor GO:0034612 56 0.360
Rat
tooth eruption GO:0044691 1 0.340
Rat
bone development GO:0060348 25 0.316
Rat
response to transforming growth factor beta GO:0071559 46 0.309
Rat
cellular response to thyroid hormone stimulus GO:0097067 5 0.249
Rat
cartilage development GO:0051216 22 0.246
Rat
skeletal system morphogenesis GO:0048705 12 0.229
Rat
regulation of epithelial to mesenchymal transition GO:0010717 2 0.222
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.197
Rat
bone morphogenesis GO:0060349 11 0.195
Rat
ossification GO:0001503 70 0.192
Rat
positive regulation of stem cell differentiation GO:2000738 2 0.184
response to acid chemical GO:0001101 222 0.183
Rat
vasculature development GO:0001944 70 0.183
cellular response to cytokine stimulus GO:0071345 127 0.182
Rat
cellular response to retinoic acid GO:0071300 27 0.179
Rat
cellular component assembly GO:0022607 360 0.179
establishment of protein localization GO:0045184 141 0.173
cellular response to oxygen containing compound GO:1901701 386 0.166
Rat
response to growth factor GO:0070848 189 0.165
Rat
cellular response to vitamin GO:0071295 21 0.154
Rat
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.154
positive regulation of intracellular protein transport GO:0090316 20 0.153
response to alkaloid GO:0043279 132 0.151
Rat
cellular response to nutrient GO:0031670 30 0.151
Rat
endochondral bone growth GO:0003416 3 0.148
Rat
response to organophosphorus GO:0046683 102 0.148
Rat
peptide cross linking GO:0018149 1 0.145
metanephric s shaped body morphogenesis GO:0072284 2 0.143
formation of primary germ layer GO:0001704 1 0.141
Human
response to retinoic acid GO:0032526 63 0.135
Rat
response to fibroblast growth factor GO:0071774 29 0.134
Rat
cellular response to acid chemical GO:0071229 75 0.132
Rat
response to nutrient levels GO:0031667 370 0.131
Rat
response to increased oxygen levels GO:0036296 45 0.128
Rat
response to catecholamine GO:0071869 16 0.127
Rat
cellular response to alkaloid GO:0071312 25 0.125
Rat
blood vessel development GO:0001568 69 0.124
embryonic skeletal system morphogenesis GO:0048704 3 0.124
transcription dna templated GO:0006351 377 0.123
extracellular fibril organization GO:0043206 1 0.121
Human
regulation of stem cell differentiation GO:2000736 2 0.119
odontogenesis GO:0042476 32 0.117
Rat
macromolecular complex subunit organization GO:0043933 339 0.115
Human
response to purine containing compound GO:0014074 126 0.114
Rat
embryonic cranial skeleton morphogenesis GO:0048701 2 0.114
regulation of cellular component organization GO:0051128 368 0.110
protein heterooligomerization GO:0051291 89 0.109
response to extracellular stimulus GO:0009991 380 0.109
Rat
cellular response to external stimulus GO:0071496 118 0.105
Rat
cellular response to organic cyclic compound GO:0071407 202 0.102
Rat
response to norepinephrine GO:0071873 5 0.102
Rat
extracellular matrix organization GO:0030198 13 0.101
Human
nucleic acid templated transcription GO:0097659 379 0.098
extracellular structure organization GO:0043062 13 0.097
Human
response to monoamine GO:0071867 17 0.096
Rat
gastrulation GO:0007369 2 0.095
Human
response to inorganic substance GO:0010035 377 0.090
Rat
cellular response to hormone stimulus GO:0032870 247 0.090
Rat
regulation of signal transduction GO:0009966 318 0.088
positive regulation of multicellular organismal process GO:0051240 387 0.086
positive regulation of transcription dna templated GO:0045893 197 0.085
salivary gland morphogenesis GO:0007435 1 0.085
circulatory system development GO:0072359 134 0.082
aging GO:0007568 241 0.082
Rat
positive regulation of developmental process GO:0051094 283 0.081
protein localization GO:0008104 191 0.078
positive regulation of locomotion GO:0040017 102 0.078
protein complex subunit organization GO:0071822 302 0.076
Human
biomineral tissue development GO:0031214 12 0.075
anatomical structure formation involved in morphogenesis GO:0048646 83 0.075
Human
response to vitamin GO:0033273 131 0.074
Rat
skin morphogenesis GO:0043589 2 0.072
intramembranous ossification GO:0001957 1 0.069
cellular response to mechanical stimulus GO:0071260 48 0.068
Rat
protein oligomerization GO:0051259 191 0.067
macromolecule localization GO:0033036 252 0.066
cellular response to epidermal growth factor stimulus GO:0071364 12 0.066
Rat
positive regulation of gene expression GO:0010628 244 0.065
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.065
biological adhesion GO:0022610 110 0.064
Human
cellular response to growth factor stimulus GO:0071363 162 0.063
Rat
protein trimerization GO:0070206 16 0.063
tube development GO:0035295 89 0.063
Human
cell morphogenesis GO:0000902 142 0.062
cellular component biogenesis GO:0044085 368 0.062
organ morphogenesis GO:0009887 75 0.061
Human Rat
salivary gland development GO:0007431 3 0.061
regulation of neuron death GO:1901214 115 0.061
response to reactive oxygen species GO:0000302 120 0.060
Rat
cellular response to nitrogen compound GO:1901699 210 0.060
Rat
positive regulation of rna metabolic process GO:0051254 203 0.060
regulation of ossification GO:0030278 32 0.058
neuron apoptotic process GO:0051402 88 0.058
response to wounding GO:0009611 254 0.057
Human Rat
response to oxygen levels GO:0070482 265 0.056
Rat
positive regulation of cell differentiation GO:0045597 217 0.055
locomotion GO:0040011 237 0.054
Human
rna metabolic process GO:0016070 406 0.054
positive regulation of nucleic acid templated transcription GO:1903508 197 0.054
regulation of transcription dna templated GO:0006355 374 0.053
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.052
cell projection organization GO:0030030 302 0.052
response to corticosteroid GO:0031960 235 0.052
Rat
response to amino acid GO:0043200 75 0.051
response to estrogen GO:0043627 232 0.050
Rat
pro t cell differentiation GO:0002572 1 0.050
intracellular signal transduction GO:0035556 314 0.050
elastic fiber assembly GO:0048251 1 0.049
transcription from rna polymerase ii promoter GO:0006366 252 0.049
response to oxidative stress GO:0006979 186 0.049
Rat
organ growth GO:0035265 24 0.047
Rat
immune system process GO:0002376 204 0.047
cardiovascular system development GO:0072358 134 0.046
multicellular organismal catabolic process GO:0044243 2 0.045
macromolecular complex assembly GO:0065003 273 0.044
anatomical structure morphogenesis GO:0009653 298 0.044
Human Rat
positive regulation of rna biosynthetic process GO:1902680 197 0.044
regulation of cellular localization GO:0060341 263 0.043
developmental growth involved in morphogenesis GO:0060560 33 0.043
Rat
s shaped body morphogenesis GO:0072050 2 0.043
response to nutrient GO:0007584 248 0.043
Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.043
small gtpase mediated signal transduction GO:0007264 36 0.043
digestive tract morphogenesis GO:0048546 8 0.043
Human
appendage morphogenesis GO:0035107 4 0.042
cellular response to endogenous stimulus GO:0071495 377 0.042
Rat
regulation of apoptotic process GO:0042981 335 0.041
regulation of anatomical structure morphogenesis GO:0022603 141 0.041
Human
blood vessel morphogenesis GO:0048514 58 0.041
cellular response to extracellular stimulus GO:0031668 73 0.041
Rat
tissue remodeling GO:0048771 40 0.040
regulation of nucleic acid templated transcription GO:1903506 380 0.040
cellular response to peptide hormone stimulus GO:0071375 120 0.040
Rat
cellular response to nutrient levels GO:0031669 60 0.040
Rat
cellular response to peptide GO:1901653 133 0.039
Rat
prostate gland epithelium morphogenesis GO:0060740 2 0.039
cellular response to fibroblast growth factor stimulus GO:0044344 24 0.039
Rat
endochondral ossification GO:0001958 2 0.039
intracellular transport GO:0046907 185 0.038
sensory organ development GO:0007423 74 0.038
Human
regulation of cell motility GO:2000145 131 0.037
central nervous system development GO:0007417 311 0.037
regulation of canonical wnt signaling pathway GO:0060828 4 0.037
regulation of cell proliferation GO:0042127 359 0.037
response to mechanical stimulus GO:0009612 134 0.037
Rat
cellular response to organonitrogen compound GO:0071417 197 0.037
Rat
response to camp GO:0051591 91 0.036
Rat
regulation of multicellular organismal development GO:2000026 376 0.036
Human
rna biosynthetic process GO:0032774 380 0.034
protein complex assembly GO:0006461 263 0.034
positive regulation of cellular component movement GO:0051272 102 0.033
cellular response to lipid GO:0071396 201 0.033
Rat
cell migration GO:0016477 197 0.032
Human
protein complex biogenesis GO:0070271 263 0.032
negative regulation of cellular biosynthetic process GO:0031327 161 0.032
response to nicotine GO:0035094 51 0.032
Rat
positive regulation of biosynthetic process GO:0009891 319 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.031
muscle organ development GO:0007517 50 0.031
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.031
regulation of vasculature development GO:1901342 44 0.031
protein transport GO:0015031 132 0.030
cell adhesion GO:0007155 110 0.030
Human
response to x ray GO:0010165 15 0.030
Rat
inner ear morphogenesis GO:0042472 1 0.030
ras protein signal transduction GO:0007265 29 0.029
cellular macromolecule localization GO:0070727 122 0.029
regulation of rna biosynthetic process GO:2001141 381 0.029
regulation of blood pressure GO:0008217 83 0.029
cellular component movement GO:0006928 248 0.028
Human
proteolysis GO:0006508 175 0.028
peptidyl lysine hydroxylation GO:0017185 1 0.028
embryonic neurocranium morphogenesis GO:0048702 2 0.027
tissue morphogenesis GO:0048729 22 0.027
Human
negative regulation of biosynthetic process GO:0009890 168 0.027
multicellular organismal reproductive process GO:0048609 233 0.026
regulation of secretion GO:0051046 224 0.026
positive regulation of metanephros development GO:0072216 2 0.026
epithelial cell differentiation GO:0030855 71 0.026
positive regulation of signal transduction GO:0009967 175 0.026
response to hydrogen peroxide GO:0042542 89 0.026
Rat
muscle organ morphogenesis GO:0048644 1 0.026
metanephric comma shaped body morphogenesis GO:0072278 2 0.025
positive regulation of response to stimulus GO:0048584 285 0.025
cell motility GO:0048870 202 0.024
Human
mast cell chemotaxis GO:0002551 4 0.024
negative regulation of gene expression GO:0010629 199 0.024
heart morphogenesis GO:0003007 3 0.024
sexual reproduction GO:0019953 148 0.024
cellular response to metal ion GO:0071248 55 0.024
limb morphogenesis GO:0035108 4 0.023
regulation of b cell differentiation GO:0045577 1 0.023
positive regulation of cellular biosynthetic process GO:0031328 295 0.023
cellular response to abiotic stimulus GO:0071214 85 0.023
Rat
blood circulation GO:0008015 183 0.023
enzyme linked receptor protein signaling pathway GO:0007167 116 0.023
response to carbohydrate GO:0009743 183 0.022
forebrain development GO:0030900 98 0.022
negative regulation of macromolecule metabolic process GO:0010605 260 0.022
regulation of phosphorus metabolic process GO:0051174 349 0.022
coronary vasculature morphogenesis GO:0060977 3 0.022
cellular response to iron iii ion GO:0071283 3 0.021
positive regulation of protein phosphorylation GO:0001934 135 0.021
response to epidermal growth factor GO:0070849 18 0.021
Rat
positive regulation of protein transport GO:0051222 41 0.021
response to hypoxia GO:0001666 231 0.021
comma shaped body morphogenesis GO:0072049 2 0.021
transforming growth factor beta receptor signaling pathway GO:0007179 18 0.021
multicellular organismal macromolecule metabolic process GO:0044259 21 0.021
Human
cellular protein localization GO:0034613 122 0.021
response to transition metal nanoparticle GO:1990267 122 0.020
apoptotic process GO:0006915 381 0.020
multi organism reproductive process GO:0044703 262 0.020
regulation of establishment of protein localization GO:0070201 69 0.020
positive regulation of angiogenesis GO:0045766 28 0.020
hindlimb morphogenesis GO:0035137 2 0.020
regulation of rna metabolic process GO:0051252 391 0.020
positive regulation of cell death GO:0010942 184 0.020
organelle organization GO:0006996 266 0.020
single organism catabolic process GO:0044712 283 0.019
insulin like growth factor receptor signaling pathway GO:0048009 3 0.019
negative regulation of metabolic process GO:0009892 331 0.019
muscle tissue morphogenesis GO:0060415 1 0.019
response to monosaccharide GO:0034284 159 0.019
localization of cell GO:0051674 202 0.019
Human
homeostatic process GO:0042592 331 0.019
multicellular organismal metabolic process GO:0044236 22 0.019
Human
single organism intracellular transport GO:1902582 166 0.019
embryonic hindlimb morphogenesis GO:0035116 2 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
cytoplasmic transport GO:0016482 115 0.018
response to thyroid hormone GO:0097066 17 0.018
Rat
protein localization to organelle GO:0033365 57 0.018
positive regulation of epithelial cell proliferation GO:0050679 32 0.018
camera type eye morphogenesis GO:0048593 2 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
growth GO:0040007 165 0.017
Rat
nuclear transport GO:0051169 49 0.017
eye morphogenesis GO:0048592 4 0.017
Human
angiogenesis involved in coronary vascular morphogenesis GO:0060978 3 0.017
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.017
cell type specific apoptotic process GO:0097285 134 0.017
neuronal stem cell maintenance GO:0097150 2 0.017
negative regulation of neuron death GO:1901215 69 0.017
regulation of cell differentiation GO:0045595 320 0.017
Human
chondrocyte differentiation GO:0002062 10 0.017
Rat
positive regulation of endothelial cell migration GO:0010595 4 0.017
regulation of protein metabolic process GO:0051246 289 0.017
metanephric glomerulus morphogenesis GO:0072275 1 0.017
digestive tract development GO:0048565 39 0.017
Human
synaptic growth at neuromuscular junction GO:0051124 1 0.017
positive regulation of synaptic plasticity GO:0031915 3 0.017
kidney vasculature development GO:0061440 6 0.016
positive regulation of cell communication GO:0010647 271 0.016
response to ionizing radiation GO:0010212 59 0.016
Rat
muscle tissue development GO:0060537 58 0.016
oxoacid metabolic process GO:0043436 290 0.016
response to estradiol GO:0032355 164 0.016
Rat
angiogenesis GO:0001525 53 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
multicellular organism growth GO:0035264 1 0.016
regulation of growth GO:0040008 105 0.016
metanephric glomerulus development GO:0072224 3 0.016
cellular ketone metabolic process GO:0042180 51 0.015
reproductive system development GO:0061458 128 0.015
regulation of cell migration GO:0030334 128 0.015
positive regulation of epithelial to mesenchymal transition GO:0010718 2 0.015
heart development GO:0007507 72 0.015
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.015
regulation of metanephros development GO:0072215 4 0.014
positive regulation of molecular function GO:0044093 230 0.014
positive regulation of intracellular transport GO:0032388 39 0.014
embryo development GO:0009790 49 0.014
Human
rho protein signal transduction GO:0007266 11 0.014
regulation of bmp signaling pathway GO:0030510 2 0.014
cell migration involved in kidney development GO:0035787 2 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
reproduction GO:0000003 245 0.014
positive regulation of cell motility GO:2000147 97 0.014
organic acid metabolic process GO:0006082 292 0.014
response to radiation GO:0009314 137 0.014
Rat
response to glucocorticoid GO:0051384 223 0.014
cation transmembrane transport GO:0098655 263 0.014
steroid metabolic process GO:0008202 73 0.014
cellular response to inorganic substance GO:0071241 65 0.014
single organism biosynthetic process GO:0044711 342 0.014
Human
osteoblast differentiation GO:0001649 26 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
female pregnancy GO:0007565 122 0.014
multicellular organismal homeostasis GO:0048871 49 0.014
regulation of programmed cell death GO:0043067 341 0.014
angioblast cell migration GO:0035476 1 0.014
regulation of reactive oxygen species metabolic process GO:2000377 26 0.013
circulatory system process GO:0003013 183 0.013
regulation of intracellular protein transport GO:0033157 34 0.013
cellular amine metabolic process GO:0044106 38 0.013
response to metal ion GO:0010038 253 0.013
embryonic pattern specification GO:0009880 1 0.013
developmental growth GO:0048589 100 0.013
Rat
cellular response to oxygen levels GO:0071453 60 0.013
renal system development GO:0072001 67 0.013
kidney development GO:0001822 67 0.013
camera type eye development GO:0043010 48 0.013
regulation of cytokine production GO:0001817 56 0.013
response to peptide GO:1901652 292 0.013
Rat
regulation of synapse assembly GO:0051963 15 0.013
negative regulation of cellular metabolic process GO:0031324 281 0.013
brain development GO:0007420 247 0.013
secretion by cell GO:0032940 248 0.013
epithelium development GO:0060429 96 0.013
Human
carbohydrate derivative metabolic process GO:1901135 346 0.013
regulation of cell development GO:0060284 263 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
response to glucose GO:0009749 136 0.012
eye development GO:0001654 50 0.012
Human
negative regulation of immune system process GO:0002683 39 0.012
tube formation GO:0035148 3 0.012
inner ear development GO:0048839 21 0.012
regulation of protein modification process GO:0031399 194 0.012
respiratory tube development GO:0030323 43 0.012
regulation of blood vessel endothelial cell migration GO:0043535 4 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
positive regulation of growth GO:0045927 55 0.012
response to peptide hormone GO:0043434 278 0.012
Rat
positive regulation of apoptotic process GO:0043065 154 0.012
positive regulation of cell migration GO:0030335 96 0.012
spindle organization GO:0007051 2 0.012
cellular response to alcohol GO:0097306 87 0.012
regulation of molecular function GO:0065009 398 0.012
regulation of protein secretion GO:0050708 28 0.012
response to cytokine GO:0034097 215 0.012
Rat
negative regulation of apoptotic process GO:0043066 181 0.012
organophosphate metabolic process GO:0019637 370 0.012
regulation of cellular amino acid metabolic process GO:0006521 2 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.011
sensory perception of light stimulus GO:0050953 3 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
metanephric mesenchymal cell migration GO:0035789 2 0.011
glycosaminoglycan biosynthetic process GO:0006024 4 0.011
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 5 0.011
cellular amino acid metabolic process GO:0006520 107 0.011
positive regulation of cell development GO:0010720 176 0.011
neuron death GO:0070997 127 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 10 0.011
regulation of secretion by cell GO:1903530 208 0.011
renin secretion into blood stream GO:0002001 1 0.011
myeloid progenitor cell differentiation GO:0002318 1 0.011
cellular response to stress GO:0033554 269 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
cellular component morphogenesis GO:0032989 155 0.011
male gonad development GO:0008584 59 0.011
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 2 0.011
bone mineralization GO:0030282 11 0.011
response to other organism GO:0051707 220 0.011
positive regulation of secretion GO:0051047 140 0.011
reproductive structure development GO:0048608 128 0.011
head development GO:0060322 247 0.011
vascular process in circulatory system GO:0003018 96 0.011
regulation of cellular amine metabolic process GO:0033238 8 0.011
regulation of protein transport GO:0051223 68 0.011
negative regulation of cell proliferation GO:0008285 119 0.010
palate development GO:0060021 2 0.010
ion transmembrane transport GO:0034220 365 0.010
tube morphogenesis GO:0035239 23 0.010
Human
purine nucleoside catabolic process GO:0006152 124 0.010
digestive system development GO:0055123 41 0.010
Human
regulation of intracellular transport GO:0032386 65 0.010
cell projection morphogenesis GO:0048858 123 0.010
regulation of metanephric mesenchymal cell migration GO:2000589 1 0.010
regulation of proteolysis GO:0030162 66 0.010
organic substance catabolic process GO:1901575 316 0.010
motor neuron axon guidance GO:0008045 1 0.010
replacement ossification GO:0036075 2 0.010
actin cytoskeleton organization GO:0030036 73 0.010
triglyceride homeostasis GO:0070328 2 0.010
regulation of synapse organization GO:0050807 19 0.010
immune response GO:0006955 104 0.010
multicellular organism reproduction GO:0032504 233 0.010

Col5a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.960
Human
musculoskeletal system disease DOID:17 0 0.960
Human
osteochondrodysplasia DOID:2256 0 0.937
bone development disease DOID:0080006 0 0.937
bone disease DOID:0080001 0 0.937
connective tissue disease DOID:65 0 0.937
Human
osteogenesis imperfecta DOID:12347 0 0.406
muscular disease DOID:0080000 0 0.185
myopathy DOID:423 0 0.126
muscular dystrophy DOID:9884 0 0.126
muscle tissue disease DOID:66 0 0.126
heart disease DOID:114 0 0.024
cardiomyopathy DOID:0050700 0 0.024
intrinsic cardiomyopathy DOID:0060036 0 0.024
cardiovascular system disease DOID:1287 0 0.024
arrhythmogenic right ventricular cardiomyopathy DOID:0050431 0 0.024
collagen disease DOID:854 0 0.023
Human
ehlers danlos syndrome DOID:13359 0 0.020
Human
nervous system disease DOID:863 0 0.016
hypertension DOID:10763 0 0.011
artery disease DOID:0050828 0 0.011
vascular disease DOID:178 0 0.011