Rattus norvegicus

0 known processes

Col5a3

collagen, type V, alpha 3

Col5a3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
vasculature development GO:0001944 70 0.186
locomotion GO:0040011 237 0.123
regulation of multicellular organismal development GO:2000026 376 0.122
response to inorganic substance GO:0010035 377 0.101
Rat
programmed cell death GO:0012501 392 0.090
tissue development GO:0009888 252 0.085
Rat
cellular component movement GO:0006928 248 0.079
catabolic process GO:0009056 351 0.077
anatomical structure morphogenesis GO:0009653 298 0.074
Rat
cell projection organization GO:0030030 302 0.068
localization of cell GO:0051674 202 0.066
circulatory system development GO:0072359 134 0.066
cell motility GO:0048870 202 0.065
cellular response to oxygen containing compound GO:1901701 386 0.062
Rat
monovalent inorganic cation transport GO:0015672 172 0.059
response to oxygen levels GO:0070482 265 0.059
Rat
organic substance catabolic process GO:1901575 316 0.059
cellular catabolic process GO:0044248 295 0.059
regulation of cellular component organization GO:0051128 368 0.058
behavior GO:0007610 205 0.056
response to wounding GO:0009611 254 0.056
Rat
transcription dna templated GO:0006351 377 0.054
blood vessel development GO:0001568 69 0.054
cation transport GO:0006812 382 0.052
positive regulation of biosynthetic process GO:0009891 319 0.051
cell migration GO:0016477 197 0.050
nucleic acid templated transcription GO:0097659 379 0.048
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.046
positive regulation of cell proliferation GO:0008284 249 0.046
cellular ion homeostasis GO:0006873 184 0.046
rna metabolic process GO:0016070 406 0.044
multicellular organismal reproductive process GO:0048609 233 0.044
ribonucleoside catabolic process GO:0042454 126 0.043
reproductive process GO:0022414 372 0.042
organophosphate metabolic process GO:0019637 370 0.041
regulation of cell development GO:0060284 263 0.041
regulation of cell proliferation GO:0042127 359 0.040
macromolecule localization GO:0033036 252 0.040
ras protein signal transduction GO:0007265 29 0.039
chemical homeostasis GO:0048878 292 0.039
epithelial cell proliferation GO:0050673 54 0.039
ribose phosphate metabolic process GO:0019693 235 0.038
cardiovascular system development GO:0072358 134 0.038
regulation of apoptotic process GO:0042981 335 0.037
macromolecular complex subunit organization GO:0043933 339 0.037
response to nutrient levels GO:0031667 370 0.037
Rat
regulation of signal transduction GO:0009966 318 0.036
regulation of rna biosynthetic process GO:2001141 381 0.035
response to metal ion GO:0010038 253 0.035
cellular divalent inorganic cation homeostasis GO:0072503 162 0.035
cytosolic calcium ion homeostasis GO:0051480 140 0.034
response to alkaloid GO:0043279 132 0.034
Rat
regulation of immune system process GO:0002682 123 0.034
limb morphogenesis GO:0035108 4 0.034
multicellular organism reproduction GO:0032504 233 0.034
homeostatic process GO:0042592 331 0.034
purine ribonucleoside catabolic process GO:0046130 124 0.033
regulation of transcription dna templated GO:0006355 374 0.033
small gtpase mediated signal transduction GO:0007264 36 0.033
apoptotic process GO:0006915 381 0.033
protein localization GO:0008104 191 0.032
regulation of cell migration GO:0030334 128 0.032
transmembrane transport GO:0055085 412 0.032
purine nucleoside metabolic process GO:0042278 169 0.032
neurological system process GO:0050877 219 0.032
cellular homeostasis GO:0019725 252 0.031
regulation of protein metabolic process GO:0051246 289 0.031
single organism catabolic process GO:0044712 283 0.031
positive regulation of cellular biosynthetic process GO:0031328 295 0.031
response to estrogen GO:0043627 232 0.031
Rat
intracellular signal transduction GO:0035556 314 0.031
muscle tissue development GO:0060537 58 0.031
organonitrogen compound catabolic process GO:1901565 179 0.031
regulation of phosphorus metabolic process GO:0051174 349 0.031
immune system process GO:0002376 204 0.031
regulation of phosphate metabolic process GO:0019220 349 0.030
cellular response to hormone stimulus GO:0032870 247 0.030
Rat
regulation of anatomical structure morphogenesis GO:0022603 141 0.030
regulation of cell differentiation GO:0045595 320 0.030
response to retinoic acid GO:0032526 63 0.030
Rat
cell morphogenesis GO:0000902 142 0.030
cellular calcium ion homeostasis GO:0006874 160 0.029
organic cyclic compound catabolic process GO:1901361 175 0.029
cellular response to external stimulus GO:0071496 118 0.029
Rat
calcium ion homeostasis GO:0055074 162 0.029
neuron differentiation GO:0030182 368 0.029
regulation of programmed cell death GO:0043067 341 0.029
response to purine containing compound GO:0014074 126 0.029
Rat
nucleotide metabolic process GO:0009117 279 0.029
cellular response to mechanical stimulus GO:0071260 48 0.029
Rat
nucleobase containing small molecule metabolic process GO:0055086 316 0.028
negative regulation of cell differentiation GO:0045596 99 0.028
response to increased oxygen levels GO:0036296 45 0.028
Rat
neuron development GO:0048666 286 0.028
purine ribonucleoside metabolic process GO:0046128 168 0.028
carbohydrate derivative metabolic process GO:1901135 346 0.028
amine metabolic process GO:0009308 38 0.028
cellular amine metabolic process GO:0044106 38 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.027
positive regulation of cell communication GO:0010647 271 0.027
anatomical structure formation involved in morphogenesis GO:0048646 83 0.027
central nervous system development GO:0007417 311 0.027
reproduction GO:0000003 245 0.026
cellular response to endogenous stimulus GO:0071495 377 0.026
Rat
positive regulation of phosphorylation GO:0042327 177 0.026
single organism cell adhesion GO:0098602 46 0.026
cellular component biogenesis GO:0044085 368 0.026
response to organophosphorus GO:0046683 102 0.026
Rat
muscle structure development GO:0061061 87 0.025
head development GO:0060322 247 0.025
rna biosynthetic process GO:0032774 380 0.025
cellular cation homeostasis GO:0030003 180 0.025
cellular response to growth factor stimulus GO:0071363 162 0.025
Rat
response to decreased oxygen levels GO:0036293 237 0.025
endochondral bone growth GO:0003416 3 0.025
Rat
ion transmembrane transport GO:0034220 365 0.025
ribonucleotide catabolic process GO:0009261 136 0.025
purine nucleoside catabolic process GO:0006152 124 0.025
nucleoside metabolic process GO:0009116 179 0.025
ion homeostasis GO:0050801 212 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.024
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.024
blood circulation GO:0008015 183 0.024
sexual reproduction GO:0019953 148 0.024
response to oxidative stress GO:0006979 186 0.024
Rat
cellular metal ion homeostasis GO:0006875 172 0.024
positive regulation of cell motility GO:2000147 97 0.024
cellular amino acid metabolic process GO:0006520 107 0.024
oxoacid metabolic process GO:0043436 290 0.023
protein complex subunit organization GO:0071822 302 0.023
organophosphate catabolic process GO:0046434 148 0.023
negative regulation of cell proliferation GO:0008285 119 0.023
neuron projection development GO:0031175 273 0.023
positive regulation of phosphate metabolic process GO:0045937 262 0.023
cellular response to stress GO:0033554 269 0.023
response to cytokine GO:0034097 215 0.023
Rat
nucleoside catabolic process GO:0009164 126 0.023
gamete generation GO:0007276 124 0.022
regulation of neurogenesis GO:0050767 247 0.022
single organism reproductive process GO:0044702 297 0.022
negative regulation of developmental process GO:0051093 125 0.022
response to fluid shear stress GO:0034405 16 0.022
ribonucleotide metabolic process GO:0009259 231 0.022
purine nucleotide catabolic process GO:0006195 136 0.022
positive regulation of cell differentiation GO:0045597 217 0.022
response to nutrient GO:0007584 248 0.022
Rat
proteolysis GO:0006508 175 0.022
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.022
eye morphogenesis GO:0048592 4 0.022
negative regulation of multicellular organismal process GO:0051241 203 0.022
regulation of neuron projection development GO:0010975 161 0.022
regulation of neuron differentiation GO:0045664 208 0.022
positive regulation of gene expression GO:0010628 244 0.021
regulation of phosphorylation GO:0042325 248 0.021
negative regulation of cell communication GO:0010648 158 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.021
response to extracellular stimulus GO:0009991 380 0.021
Rat
cellular component assembly GO:0022607 360 0.021
response to hypoxia GO:0001666 231 0.021
response to low density lipoprotein particle GO:0055098 4 0.021
gtp metabolic process GO:0046039 72 0.021
purine nucleoside triphosphate metabolic process GO:0009144 141 0.021
s shaped body morphogenesis GO:0072050 2 0.020
ribonucleoside triphosphate metabolic process GO:0009199 141 0.020
tube development GO:0035295 89 0.020
positive regulation of multicellular organismal process GO:0051240 387 0.020
organophosphate biosynthetic process GO:0090407 143 0.020
positive regulation of developmental process GO:0051094 283 0.020
cellular chemical homeostasis GO:0055082 247 0.020
response to carbohydrate GO:0009743 183 0.019
aromatic compound catabolic process GO:0019439 168 0.019
positive regulation of response to stimulus GO:0048584 285 0.019
embryonic appendage morphogenesis GO:0035113 4 0.019
blood vessel morphogenesis GO:0048514 58 0.019
regulation of cellular component movement GO:0051270 150 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
response to monosaccharide GO:0034284 159 0.019
regulation of cell projection organization GO:0031344 175 0.019
response to molecule of bacterial origin GO:0002237 194 0.019
cellular response to organic cyclic compound GO:0071407 202 0.019
Rat
regulation of nervous system development GO:0051960 264 0.019
small molecule biosynthetic process GO:0044283 124 0.019
cellular response to low density lipoprotein particle stimulus GO:0071404 3 0.019
regulation of molecular function GO:0065009 398 0.019
metal ion transport GO:0030001 289 0.019
response to growth factor GO:0070848 189 0.019
Rat
positive regulation of molecular function GO:0044093 230 0.019
nucleoside phosphate catabolic process GO:1901292 140 0.019
oxidation reduction process GO:0055114 304 0.018
regulation of small gtpase mediated signal transduction GO:0051056 48 0.018
heterocycle catabolic process GO:0046700 167 0.018
single organism biosynthetic process GO:0044711 342 0.018
brain development GO:0007420 247 0.018
regulation of response to external stimulus GO:0032101 106 0.018
positive regulation of signaling GO:0023056 270 0.018
protein phosphorylation GO:0006468 345 0.018
aging GO:0007568 241 0.018
Rat
embryonic skeletal system morphogenesis GO:0048704 3 0.018
negative regulation of biosynthetic process GO:0009890 168 0.018
cellular response to peptide GO:1901653 133 0.018
Rat
positive regulation of nervous system development GO:0051962 178 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
response to acid chemical GO:0001101 222 0.017
Rat
ribonucleoside metabolic process GO:0009119 174 0.017
regulation of synaptic transmission GO:0050804 141 0.017
organelle organization GO:0006996 266 0.017
ribonucleoside triphosphate catabolic process GO:0009203 122 0.017
regulation of anatomical structure size GO:0090066 135 0.017
rho protein signal transduction GO:0007266 11 0.017
positive regulation of apoptotic process GO:0043065 154 0.017
reproductive structure development GO:0048608 128 0.017
purine ribonucleotide catabolic process GO:0009154 136 0.017
regulation of growth GO:0040008 105 0.017
nucleoside triphosphate catabolic process GO:0009143 123 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
cation transmembrane transport GO:0098655 263 0.017
energy derivation by oxidation of organic compounds GO:0015980 46 0.017
cellular response to retinoic acid GO:0071300 27 0.017
Rat
response to hyperoxia GO:0055093 45 0.017
Rat
cellular nitrogen compound catabolic process GO:0044270 163 0.017
purine containing compound catabolic process GO:0072523 138 0.017
carboxylic acid metabolic process GO:0019752 289 0.017
angiogenesis GO:0001525 53 0.017
glycosyl compound catabolic process GO:1901658 126 0.016
growth GO:0040007 165 0.016
Rat
regulation of ion transmembrane transport GO:0034765 121 0.016
regulation of epithelial cell proliferation GO:0050678 49 0.016
positive regulation of epithelial cell proliferation GO:0050679 32 0.016
choline transport GO:0015871 4 0.016
vesicle mediated transport GO:0016192 181 0.016
regulation of rna metabolic process GO:0051252 391 0.016
carbohydrate derivative catabolic process GO:1901136 147 0.016
nucleobase containing compound catabolic process GO:0034655 152 0.016
development of primary female sexual characteristics GO:0046545 56 0.016
response to glucose GO:0009749 136 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
response to tumor necrosis factor GO:0034612 56 0.016
Rat
skeletal system development GO:0001501 41 0.016
Rat
gonad development GO:0008406 104 0.016
nucleoside phosphate metabolic process GO:0006753 283 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
response to ionizing radiation GO:0010212 59 0.016
Rat
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
respiratory gaseous exchange GO:0007585 4 0.016
digestive system development GO:0055123 41 0.016
inorganic cation transmembrane transport GO:0098662 202 0.015
potassium ion transport GO:0006813 97 0.015
positive regulation of catabolic process GO:0009896 78 0.015
regulation of cell motility GO:2000145 131 0.015
response to lipopolysaccharide GO:0032496 191 0.015
glycosyl compound metabolic process GO:1901657 182 0.015
heart morphogenesis GO:0003007 3 0.015
purine containing compound metabolic process GO:0072521 253 0.015
cellular ketone metabolic process GO:0042180 51 0.015
development of primary sexual characteristics GO:0045137 107 0.015
organic acid metabolic process GO:0006082 292 0.015
appendage morphogenesis GO:0035107 4 0.015
aorta development GO:0035904 2 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
cellular carbohydrate metabolic process GO:0044262 72 0.015
regulation of response to wounding GO:1903034 69 0.015
guanosine containing compound catabolic process GO:1901069 71 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
negative regulation of transport GO:0051051 136 0.015
lipid biosynthetic process GO:0008610 128 0.015
transformation of host cell by virus GO:0019087 4 0.015
b cell differentiation GO:0030183 2 0.014
regulation of catabolic process GO:0009894 113 0.014
divalent inorganic cation homeostasis GO:0072507 165 0.014
protein complex assembly GO:0006461 263 0.014
regulation of nucleic acid templated transcription GO:1903506 380 0.014
multicellular organismal homeostasis GO:0048871 49 0.014
positive regulation of transport GO:0051050 245 0.014
cell type specific apoptotic process GO:0097285 134 0.014
action potential GO:0001508 54 0.014
regulation of g0 to g1 transition GO:0070316 3 0.014
cell adhesion GO:0007155 110 0.014
cellular component morphogenesis GO:0032989 155 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
axis specification GO:0009798 4 0.014
positive regulation of transcription dna templated GO:0045893 197 0.014
purine nucleoside triphosphate catabolic process GO:0009146 122 0.014
organic hydroxy compound metabolic process GO:1901615 115 0.014
regulation of protein modification process GO:0031399 194 0.014
response to biotic stimulus GO:0009607 226 0.014
positive regulation of rna metabolic process GO:0051254 203 0.014
divalent inorganic cation transport GO:0072511 134 0.014
divalent metal ion transport GO:0070838 132 0.014
positive regulation of signal transduction GO:0009967 175 0.014
vascular process in circulatory system GO:0003018 96 0.014
formation of primary germ layer GO:0001704 1 0.014
dna metabolic process GO:0006259 96 0.014
secretion GO:0046903 307 0.014
spermatogenesis GO:0007283 99 0.014
cation homeostasis GO:0055080 195 0.013
positive regulation of cell death GO:0010942 184 0.013
regulation of proteasomal protein catabolic process GO:0061136 4 0.013
neuronal action potential GO:0019228 35 0.013
regulation of membrane potential GO:0042391 110 0.013
positive regulation of rna biosynthetic process GO:1902680 197 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
muscle organ development GO:0007517 50 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
skeletal muscle organ development GO:0060538 33 0.013
regulation of cellular amine metabolic process GO:0033238 8 0.013
neuron apoptotic process GO:0051402 88 0.013
anterior posterior pattern specification GO:0009952 1 0.013
response to corticosteroid GO:0031960 235 0.013
Rat
nucleotide catabolic process GO:0009166 139 0.013
gastrulation GO:0007369 2 0.013
rhythmic process GO:0048511 156 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
response to bacterium GO:0009617 200 0.013
negative regulation of metabolic process GO:0009892 331 0.013
regeneration GO:0031099 163 0.013
cellular macromolecule localization GO:0070727 122 0.013
response to peptide hormone GO:0043434 278 0.013
Rat
calcium ion transport GO:0006816 131 0.013
myelination GO:0042552 39 0.012
defense response GO:0006952 194 0.012
regulation of system process GO:0044057 208 0.012
circulatory system process GO:0003013 183 0.012
bmp signaling pathway GO:0030509 4 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
reproductive system development GO:0061458 128 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
macromolecular complex assembly GO:0065003 273 0.012
spindle organization GO:0007051 2 0.012
metal ion homeostasis GO:0055065 186 0.012
positive regulation of fatty acid beta oxidation GO:0032000 4 0.012
regulation of homeostatic process GO:0032844 101 0.012
regulation of transmembrane transport GO:0034762 122 0.012
protein complex biogenesis GO:0070271 263 0.012
cell cell signaling GO:0007267 335 0.012
multicellular organismal signaling GO:0035637 44 0.012
regulation of hydrolase activity GO:0051336 143 0.012
cellular response to fluid shear stress GO:0071498 4 0.012
chemosensory behavior GO:0007635 2 0.012
male gamete generation GO:0048232 99 0.012
membrane organization GO:0061024 94 0.012
regulation of secretion GO:0051046 224 0.012
cartilage development GO:0051216 22 0.012
Rat
gtp catabolic process GO:0006184 71 0.011
regulation of fat cell differentiation GO:0045598 3 0.011
transmission of nerve impulse GO:0019226 42 0.011
negative regulation of cell development GO:0010721 82 0.011
biological adhesion GO:0022610 110 0.011
palate development GO:0060021 2 0.011
salivary gland morphogenesis GO:0007435 1 0.011
regulation of bmp signaling pathway GO:0030510 2 0.011
negative regulation of nervous system development GO:0051961 79 0.011
coronary vasculature morphogenesis GO:0060977 3 0.011
endomembrane system organization GO:0010256 48 0.011
sex differentiation GO:0007548 113 0.011
intracellular transport GO:0046907 185 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
cellular response to alcohol GO:0097306 87 0.011
inflammatory response GO:0006954 150 0.011
positive regulation of fat cell differentiation GO:0045600 2 0.011
regulation of ion transport GO:0043269 245 0.011
response to mechanical stimulus GO:0009612 134 0.011
Rat
single organism behavior GO:0044708 130 0.011
sequestering of calcium ion GO:0051208 8 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
camera type eye morphogenesis GO:0048593 2 0.011
hindlimb morphogenesis GO:0035137 2 0.011
regulation of respiratory gaseous exchange GO:0043576 2 0.011
regulation of metal ion transport GO:0010959 118 0.011
regulation of muscle organ development GO:0048634 26 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
synaptic transmission GO:0007268 235 0.011
monocarboxylic acid metabolic process GO:0032787 152 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
developmental process involved in reproduction GO:0003006 159 0.011
cell projection morphogenesis GO:0048858 123 0.011
embryonic pattern specification GO:0009880 1 0.011
positive regulation of cell development GO:0010720 176 0.011
regulation of cellular localization GO:0060341 263 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
cell growth GO:0016049 104 0.011
protein autophosphorylation GO:0046777 66 0.011
mechanoreceptor differentiation GO:0042490 2 0.011
cellular response to nitrogen compound GO:1901699 210 0.010
Rat
response to activity GO:0014823 73 0.010
regulation of mapk cascade GO:0043408 116 0.010
positive regulation of phosphorus metabolic process GO:0010562 262 0.010
regulation of catalytic activity GO:0050790 304 0.010
negative regulation of cell death GO:0060548 229 0.010
adult locomotory behavior GO:0008344 4 0.010
negative regulation of signaling GO:0023057 157 0.010
positive regulation of intracellular signal transduction GO:1902533 138 0.010
regulation of embryonic development GO:0045995 2 0.010
sodium ion transport GO:0006814 82 0.010
cellular response to iron iii ion GO:0071283 3 0.010
salivary gland development GO:0007431 3 0.010
cellular response to corticosteroid stimulus GO:0071384 69 0.010

Col5a3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.048
sensory system disease DOID:0050155 0 0.048
eye disease DOID:5614 0 0.048
eye and adnexa disease DOID:1492 0 0.048
disease of anatomical entity DOID:7 0 0.048
musculoskeletal system disease DOID:17 0 0.042
retinal degeneration DOID:8466 0 0.028
retinal disease DOID:5679 0 0.028
connective tissue disease DOID:65 0 0.021
bone disease DOID:0080001 0 0.021
bone development disease DOID:0080006 0 0.019
muscular disease DOID:0080000 0 0.014
muscle tissue disease DOID:66 0 0.014
retinitis pigmentosa DOID:10584 0 0.013
osteochondrodysplasia DOID:2256 0 0.012