Rattus norvegicus

14 known processes

Crispld2

cysteine-rich secretory protein LCCL domain containing 2

(Aliases: Lcrisp2,Lgl1)

Crispld2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein complex subunit organization GO:0071822 302 0.123
tissue development GO:0009888 252 0.122
reproductive process GO:0022414 372 0.118
Fly
anatomical structure morphogenesis GO:0009653 298 0.113
Human
cellular response to endogenous stimulus GO:0071495 377 0.107
circulatory system development GO:0072359 134 0.106
response to peptide GO:1901652 292 0.100
cell migration GO:0016477 197 0.094
cardiovascular system development GO:0072358 134 0.093
response to nutrient levels GO:0031667 370 0.090
regulation of phosphorus metabolic process GO:0051174 349 0.085
cellular response to growth factor stimulus GO:0071363 162 0.085
response to cytokine GO:0034097 215 0.084
organic acid metabolic process GO:0006082 292 0.083
single organism reproductive process GO:0044702 297 0.081
intracellular signal transduction GO:0035556 314 0.080
positive regulation of phosphorus metabolic process GO:0010562 262 0.076
cellular response to cytokine stimulus GO:0071345 127 0.073
protein complex assembly GO:0006461 263 0.073
response to inorganic substance GO:0010035 377 0.072
positive regulation of response to stimulus GO:0048584 285 0.071
macromolecular complex assembly GO:0065003 273 0.070
carboxylic acid metabolic process GO:0019752 289 0.069
response to biotic stimulus GO:0009607 226 0.068
response to growth factor GO:0070848 189 0.067
regulation of phosphorylation GO:0042325 248 0.067
cellular response to oxygen containing compound GO:1901701 386 0.065
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.064
negative regulation of metabolic process GO:0009892 331 0.064
cellular response to peptide hormone stimulus GO:0071375 120 0.063
cellular response to hormone stimulus GO:0032870 247 0.062
positive regulation of signal transduction GO:0009967 175 0.059
cellular component movement GO:0006928 248 0.057
positive regulation of transport GO:0051050 245 0.056
macromolecular complex subunit organization GO:0043933 339 0.054
blood vessel morphogenesis GO:0048514 58 0.052
regulation of signal transduction GO:0009966 318 0.052
small gtpase mediated signal transduction GO:0007264 36 0.051
response to estrogen GO:0043627 232 0.051
nucleic acid templated transcription GO:0097659 379 0.051
positive regulation of cellular biosynthetic process GO:0031328 295 0.050
vasculature development GO:0001944 70 0.049
regulation of rna metabolic process GO:0051252 391 0.048
oxoacid metabolic process GO:0043436 290 0.048
multicellular organismal reproductive process GO:0048609 233 0.047
Fly
multicellular organism reproduction GO:0032504 233 0.046
Fly
mapk cascade GO:0000165 140 0.046
cell motility GO:0048870 202 0.045
rhythmic process GO:0048511 156 0.044
response to decreased oxygen levels GO:0036293 237 0.044
response to oxygen levels GO:0070482 265 0.043
response to hypoxia GO:0001666 231 0.042
response to peptide hormone GO:0043434 278 0.042
rna metabolic process GO:0016070 406 0.040
cellular catabolic process GO:0044248 295 0.039
protein phosphorylation GO:0006468 345 0.039
cellular amino acid metabolic process GO:0006520 107 0.039
cation transmembrane transport GO:0098655 263 0.038
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.038
regulation of multicellular organismal development GO:2000026 376 0.038
positive regulation of cell motility GO:2000147 97 0.037
response to lipopolysaccharide GO:0032496 191 0.037
ras protein signal transduction GO:0007265 29 0.037
positive regulation of phosphate metabolic process GO:0045937 262 0.037
regulation of phosphate metabolic process GO:0019220 349 0.037
cellular response to organonitrogen compound GO:0071417 197 0.037
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.037
vesicle mediated transport GO:0016192 181 0.037
catabolic process GO:0009056 351 0.036
cellular component biogenesis GO:0044085 368 0.036
multi multicellular organism process GO:0044706 138 0.036
Fly
cellular response to stress GO:0033554 269 0.035
multi organism reproductive process GO:0044703 262 0.035
Fly
protein oligomerization GO:0051259 191 0.035
positive regulation of phosphorylation GO:0042327 177 0.035
cell projection organization GO:0030030 302 0.035
positive regulation of apoptotic process GO:0043065 154 0.035
negative regulation of multicellular organismal process GO:0051241 203 0.034
cellular component assembly GO:0022607 360 0.034
response to glucocorticoid GO:0051384 223 0.034
regulation of cell differentiation GO:0045595 320 0.034
reproduction GO:0000003 245 0.033
Fly
organophosphate metabolic process GO:0019637 370 0.033
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.033
amine metabolic process GO:0009308 38 0.032
response to corticosteroid GO:0031960 235 0.031
regulation of nucleic acid templated transcription GO:1903506 380 0.031
localization of cell GO:0051674 202 0.031
organic substance catabolic process GO:1901575 316 0.031
positive regulation of gene expression GO:0010628 244 0.031
response to nutrient GO:0007584 248 0.031
positive regulation of cell communication GO:0010647 271 0.030
intracellular transport GO:0046907 185 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.030
rna biosynthetic process GO:0032774 380 0.030
cellular response to lipid GO:0071396 201 0.030
regulation of cell proliferation GO:0042127 359 0.030
neuron projection development GO:0031175 273 0.030
female pregnancy GO:0007565 122 0.029
negative regulation of cellular metabolic process GO:0031324 281 0.029
endocytosis GO:0006897 84 0.029
response to metal ion GO:0010038 253 0.029
positive regulation of signaling GO:0023056 270 0.029
protein complex biogenesis GO:0070271 263 0.029
anion transport GO:0006820 178 0.029
response to extracellular stimulus GO:0009991 380 0.028
transmembrane transport GO:0055085 412 0.028
neuron differentiation GO:0030182 368 0.028
homeostatic process GO:0042592 331 0.028
regulation of intracellular signal transduction GO:1902531 218 0.028
regulation of cellular ketone metabolic process GO:0010565 27 0.028
response to interleukin 2 GO:0070669 1 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
regulation of cellular amine metabolic process GO:0033238 8 0.028
response to interleukin 1 GO:0070555 55 0.027
nucleobase containing small molecule metabolic process GO:0055086 316 0.027
negative regulation of protein metabolic process GO:0051248 114 0.027
mast cell migration GO:0097531 4 0.027
single organism intracellular transport GO:1902582 166 0.027
cellular response to organic cyclic compound GO:0071407 202 0.027
regulation of catalytic activity GO:0050790 304 0.027
positive regulation of intracellular signal transduction GO:1902533 138 0.027
tissue remodeling GO:0048771 40 0.027
taxis GO:0042330 67 0.026
cell cell signaling GO:0007267 335 0.026
regulation of molecular function GO:0065009 398 0.026
protein homooligomerization GO:0051260 91 0.026
protein transport GO:0015031 132 0.025
organ morphogenesis GO:0009887 75 0.025
reproductive system development GO:0061458 128 0.025
negative regulation of cell proliferation GO:0008285 119 0.025
secretion GO:0046903 307 0.025
cation transport GO:0006812 382 0.025
anatomical structure formation involved in morphogenesis GO:0048646 83 0.025
regulation of system process GO:0044057 208 0.024
growth GO:0040007 165 0.024
positive regulation of cellular component organization GO:0051130 200 0.024
positive regulation of cell death GO:0010942 184 0.024
protein localization GO:0008104 191 0.024
ion transmembrane transport GO:0034220 365 0.023
cellular response to external stimulus GO:0071496 118 0.023
aging GO:0007568 241 0.023
regulation of cellular protein metabolic process GO:0032268 267 0.023
reproductive structure development GO:0048608 128 0.023
regulation of jnk cascade GO:0046328 19 0.023
positive regulation of intracellular transport GO:0032388 39 0.022
cardiac chamber development GO:0003205 1 0.022
single organism biosynthetic process GO:0044711 342 0.022
macromolecule localization GO:0033036 252 0.022
cellular amine metabolic process GO:0044106 38 0.022
response to glucose GO:0009749 136 0.022
response to estradiol GO:0032355 164 0.022
kidney development GO:0001822 67 0.022
cellular response to interleukin 2 GO:0071352 1 0.022
salivary gland development GO:0007431 3 0.022
negative regulation of cell communication GO:0010648 158 0.022
regulation of cellular component organization GO:0051128 368 0.022
cellular ketone metabolic process GO:0042180 51 0.022
response to hexose GO:0009746 144 0.022
respiratory system development GO:0060541 45 0.022
locomotion GO:0040011 237 0.022
positive regulation of developmental process GO:0051094 283 0.022
neuron apoptotic process GO:0051402 88 0.022
regulation of rna biosynthetic process GO:2001141 381 0.021
negative regulation of developmental process GO:0051093 125 0.021
blood vessel development GO:0001568 69 0.021
regulation of mapk cascade GO:0043408 116 0.021
regulation of cell migration GO:0030334 128 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.021
response to carbohydrate GO:0009743 183 0.021
regulation of programmed cell death GO:0043067 341 0.021
ossification GO:0001503 70 0.021
regulation of protein metabolic process GO:0051246 289 0.021
hindlimb morphogenesis GO:0035137 2 0.021
positive regulation of biosynthetic process GO:0009891 319 0.021
ribonucleotide metabolic process GO:0009259 231 0.021
regulation of respiratory gaseous exchange GO:0043576 2 0.021
carbohydrate derivative metabolic process GO:1901135 346 0.020
immune system process GO:0002376 204 0.020
proteolysis GO:0006508 175 0.020
neuron death GO:0070997 127 0.020
apoptotic process GO:0006915 381 0.020
regulation of neurogenesis GO:0050767 247 0.020
response to other organism GO:0051707 220 0.020
regulation of transcription dna templated GO:0006355 374 0.020
rho protein signal transduction GO:0007266 11 0.020
response to vitamin GO:0033273 131 0.020
negative regulation of signaling GO:0023057 157 0.019
chemical homeostasis GO:0048878 292 0.019
negative regulation of transcription dna templated GO:0045892 116 0.019
positive regulation of blood coagulation GO:0030194 4 0.019
cellular response to alcohol GO:0097306 87 0.019
single organism catabolic process GO:0044712 283 0.019
cytosolic calcium ion homeostasis GO:0051480 140 0.019
gland development GO:0048732 155 0.019
response to purine containing compound GO:0014074 126 0.018
gastrulation GO:0007369 2 0.018
regulation of response to stress GO:0080134 126 0.018
cellular response to nitrogen compound GO:1901699 210 0.018
regeneration GO:0031099 163 0.018
mast cell chemotaxis GO:0002551 4 0.018
sexual reproduction GO:0019953 148 0.018
Fly
response to monosaccharide GO:0034284 159 0.018
response to mechanical stimulus GO:0009612 134 0.018
enzyme linked receptor protein signaling pathway GO:0007167 116 0.018
negative regulation of macromolecule metabolic process GO:0010605 260 0.018
response to acid chemical GO:0001101 222 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
positive regulation of secretion GO:0051047 140 0.018
programmed cell death GO:0012501 392 0.018
neural crest cell differentiation GO:0014033 2 0.017
developmental process involved in reproduction GO:0003006 159 0.017
development of primary sexual characteristics GO:0045137 107 0.017
regulation of establishment of protein localization GO:0070201 69 0.017
regulation of metanephros development GO:0072215 4 0.017
nucleotide metabolic process GO:0009117 279 0.017
blood circulation GO:0008015 183 0.017
regulation of neuron projection development GO:0010975 161 0.017
neuron development GO:0048666 286 0.017
transcription from rna polymerase ii promoter GO:0006366 252 0.017
angiogenesis GO:0001525 53 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
response to ketone GO:1901654 182 0.017
regulation of anatomical structure size GO:0090066 135 0.017
inorganic ion transmembrane transport GO:0098660 229 0.016
positive regulation of molecular function GO:0044093 230 0.016
axis specification GO:0009798 4 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
protein maturation GO:0051604 68 0.016
positive regulation of multicellular organismal process GO:0051240 387 0.016
lipid metabolic process GO:0006629 283 0.016
negative regulation of gene expression GO:0010629 199 0.016
regulation of metalloenzyme activity GO:0048552 1 0.016
negative regulation of cell differentiation GO:0045596 99 0.016
embryonic skeletal system development GO:0048706 3 0.016
l glutamate import GO:0051938 2 0.016
regulation of cellular response to stress GO:0080135 49 0.016
positive regulation of cell migration GO:0030335 96 0.016
response to oxidative stress GO:0006979 186 0.016
intracellular protein transport GO:0006886 79 0.016
secretion by cell GO:0032940 248 0.016
regulation of cellular component movement GO:0051270 150 0.016
nitrogen compound transport GO:0071705 229 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
positive regulation of cell proliferation GO:0008284 249 0.015
regulation of hormone levels GO:0010817 187 0.015
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.015
coronary vasculature morphogenesis GO:0060977 3 0.015
organelle organization GO:0006996 266 0.015
defense response GO:0006952 194 0.015
regulation of canonical wnt signaling pathway GO:0060828 4 0.015
carboxylic acid transport GO:0046942 115 0.015
cellular macromolecule localization GO:0070727 122 0.015
growth plate cartilage development GO:0003417 2 0.015
nucleoside phosphate metabolic process GO:0006753 283 0.015
cellular response to peptide GO:1901653 133 0.015
negative regulation of response to stimulus GO:0048585 155 0.015
gland morphogenesis GO:0022612 12 0.015
sex differentiation GO:0007548 113 0.015
lipid transport GO:0006869 61 0.015
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.015
response to hydrogen peroxide GO:0042542 89 0.015
positive regulation of intracellular protein transport GO:0090316 20 0.015
negative regulation of molecular function GO:0044092 133 0.015
wound healing GO:0042060 122 0.015
ovulation cycle GO:0042698 67 0.015
regulation of anatomical structure morphogenesis GO:0022603 141 0.015
gtp catabolic process GO:0006184 71 0.014
regulation of g0 to g1 transition GO:0070316 3 0.014
regulation of cell motility GO:2000145 131 0.014
chemotaxis GO:0006935 66 0.014
gamete generation GO:0007276 124 0.014
positive regulation of cell projection organization GO:0031346 111 0.014
organic anion transport GO:0015711 132 0.014
regulation of nervous system development GO:0051960 264 0.014
positive regulation of rna metabolic process GO:0051254 203 0.014
circulatory system process GO:0003013 183 0.014
response to amino acid GO:0043200 75 0.014
positive regulation of locomotion GO:0040017 102 0.014
epithelial cell differentiation GO:0030855 71 0.014
regulation of ion transmembrane transport GO:0034765 121 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.014
positive regulation of neuron projection development GO:0010976 99 0.014
salivary gland morphogenesis GO:0007435 1 0.014
negative regulation of rna biosynthetic process GO:1902679 118 0.014
regulation of bmp signaling pathway GO:0030510 2 0.014
inflammatory response GO:0006954 150 0.013
development of primary female sexual characteristics GO:0046545 56 0.013
regulation of vesicle mediated transport GO:0060627 81 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
response to bacterium GO:0009617 200 0.013
guanosine containing compound metabolic process GO:1901068 74 0.013
ion homeostasis GO:0050801 212 0.013
regulation of stress activated mapk cascade GO:0032872 23 0.013
cell part morphogenesis GO:0032990 123 0.013
skeletal system development GO:0001501 41 0.013
cation homeostasis GO:0055080 195 0.013
regulation of growth GO:0040008 105 0.013
metal ion transport GO:0030001 289 0.013
transcription dna templated GO:0006351 377 0.013
multicellular organismal signaling GO:0035637 44 0.013
tube development GO:0035295 89 0.013
regulation of vasculature development GO:1901342 44 0.013
non canonical wnt signaling pathway GO:0035567 3 0.013
regulation of cell development GO:0060284 263 0.013
positive regulation of neuron death GO:1901216 43 0.013
response to wounding GO:0009611 254 0.013
heart morphogenesis GO:0003007 3 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
developmental growth GO:0048589 100 0.013
cellular response to abiotic stimulus GO:0071214 85 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
cell type specific apoptotic process GO:0097285 134 0.013
eye development GO:0001654 50 0.013
hormone metabolic process GO:0042445 69 0.013
response to transition metal nanoparticle GO:1990267 122 0.013
positive regulation of programmed cell death GO:0043068 157 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.012
purine containing compound metabolic process GO:0072521 253 0.012
regulation of secretion by cell GO:1903530 208 0.012
lipid biosynthetic process GO:0008610 128 0.012
limb morphogenesis GO:0035108 4 0.012
regulation of apoptotic process GO:0042981 335 0.012
metal ion homeostasis GO:0055065 186 0.012
establishment of protein localization GO:0045184 141 0.012
positive regulation of nucleic acid templated transcription GO:1903508 197 0.012
peptidyl amino acid modification GO:0018193 126 0.012
regulation of transmembrane transport GO:0034762 122 0.012
ribose phosphate metabolic process GO:0019693 235 0.012
negative regulation of cell death GO:0060548 229 0.012
positive regulation of transcription dna templated GO:0045893 197 0.012
positive regulation of cell differentiation GO:0045597 217 0.012
plasminogen activation GO:0031639 2 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
regulation of membrane potential GO:0042391 110 0.012
muscle organ development GO:0007517 50 0.012
actin cytoskeleton organization GO:0030036 73 0.012
s shaped body morphogenesis GO:0072050 2 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
response to activity GO:0014823 73 0.012
organic hydroxy compound transport GO:0015850 77 0.012
synaptic transmission GO:0007268 235 0.012
response to organophosphorus GO:0046683 102 0.012
stress activated mapk cascade GO:0051403 35 0.012
epithelium development GO:0060429 96 0.012
regulation of neuron death GO:1901214 115 0.011
organophosphate catabolic process GO:0046434 148 0.011
regulation of epithelial cell differentiation GO:0030856 12 0.011
regulation of synaptic transmission GO:0050804 141 0.011
guanosine containing compound catabolic process GO:1901069 71 0.011
response to alkaloid GO:0043279 132 0.011
response to insulin GO:0032868 133 0.011
cellular ion homeostasis GO:0006873 184 0.011
muscle cell migration GO:0014812 36 0.011
heart valve morphogenesis GO:0003179 1 0.011
regulation of intracellular transport GO:0032386 65 0.011
cell morphogenesis GO:0000902 142 0.011
cytoplasmic transport GO:0016482 115 0.011
gonad development GO:0008406 104 0.011
lung development GO:0030324 43 0.011
regulation of neuron apoptotic process GO:0043523 83 0.011
cellular homeostasis GO:0019725 252 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
response to external biotic stimulus GO:0043207 221 0.011
steroid metabolic process GO:0008202 73 0.011
neural crest cell development GO:0014032 2 0.011
neuronal action potential GO:0019228 35 0.011
muscle structure development GO:0061061 87 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
signal transduction by phosphorylation GO:0023014 144 0.010
regulation of peptide transport GO:0090087 87 0.010
negative regulation of programmed cell death GO:0043069 183 0.010
regulation of p38mapk cascade GO:1900744 1 0.010
regulation of blood pressure GO:0008217 83 0.010
positive regulation of hemostasis GO:1900048 4 0.010
regulation of response to wounding GO:1903034 69 0.010
purine containing compound biosynthetic process GO:0072522 85 0.010
endomembrane system organization GO:0010256 48 0.010
cardiac ventricle development GO:0003231 1 0.010
eye morphogenesis GO:0048592 4 0.010
regulation of endothelial cell differentiation GO:0045601 4 0.010
negative regulation of nucleic acid templated transcription GO:1903507 117 0.010
organonitrogen compound catabolic process GO:1901565 179 0.010
dendrite development GO:0016358 72 0.010
inorganic cation transmembrane transport GO:0098662 202 0.010
regulation of cell morphogenesis GO:0022604 77 0.010
cardiac cell development GO:0055006 16 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.010
cytoskeleton organization GO:0007010 111 0.010
multicellular organismal homeostasis GO:0048871 49 0.010
negative regulation of signal transduction GO:0009968 83 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.010

Crispld2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.012
vascular disease DOID:178 0 0.011
cardiovascular system disease DOID:1287 0 0.011
artery disease DOID:0050828 0 0.011
central nervous system disease DOID:331 0 0.010