Rattus norvegicus

14 known processes

Crygb

crystallin, gamma B

(Aliases: Cryg2,Len)

Crygb biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of rna metabolic process GO:0051252 391 0.309
regulation of rna biosynthetic process GO:2001141 381 0.200
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.179
aging GO:0007568 241 0.173
rna metabolic process GO:0016070 406 0.157
positive regulation of developmental process GO:0051094 283 0.155
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.154
organic acid metabolic process GO:0006082 292 0.151
positive regulation of transcription dna templated GO:0045893 197 0.144
regulation of transcription dna templated GO:0006355 374 0.142
nucleic acid templated transcription GO:0097659 379 0.141
negative regulation of nucleic acid templated transcription GO:1903507 117 0.134
anatomical structure morphogenesis GO:0009653 298 0.132
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.131
rna biosynthetic process GO:0032774 380 0.130
carboxylic acid metabolic process GO:0019752 289 0.125
transcription from rna polymerase ii promoter GO:0006366 252 0.121
eye development GO:0001654 50 0.121
negative regulation of cellular metabolic process GO:0031324 281 0.117
positive regulation of biosynthetic process GO:0009891 319 0.116
lens development in camera type eye GO:0002088 13 0.113
negative regulation of macromolecule metabolic process GO:0010605 260 0.108
cellular catabolic process GO:0044248 295 0.106
positive regulation of cell differentiation GO:0045597 217 0.105
negative regulation of transcription dna templated GO:0045892 116 0.103
oxoacid metabolic process GO:0043436 290 0.094
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.090
tissue development GO:0009888 252 0.086
Rat
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.086
developmental growth GO:0048589 100 0.084
regulation of nucleic acid templated transcription GO:1903506 380 0.084
transcription dna templated GO:0006351 377 0.082
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.081
renal system development GO:0072001 67 0.080
endocytosis GO:0006897 84 0.080
response to corticosteroid GO:0031960 235 0.076
muscle system process GO:0003012 115 0.075
brain development GO:0007420 247 0.072
negative regulation of rna metabolic process GO:0051253 123 0.070
negative regulation of rna biosynthetic process GO:1902679 118 0.068
negative regulation of cellular biosynthetic process GO:0031327 161 0.066
positive regulation of rna metabolic process GO:0051254 203 0.065
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.064
regulation of multicellular organismal development GO:2000026 376 0.064
vasculature development GO:0001944 70 0.064
catabolic process GO:0009056 351 0.062
cell migration GO:0016477 197 0.061
response to glucocorticoid GO:0051384 223 0.061
kidney development GO:0001822 67 0.061
regulation of cell differentiation GO:0045595 320 0.060
positive regulation of cellular biosynthetic process GO:0031328 295 0.060
anterior posterior pattern specification GO:0009952 1 0.060
positive regulation of cell development GO:0010720 176 0.059
positive regulation of cell proliferation GO:0008284 249 0.059
regulation of cell development GO:0060284 263 0.059
positive regulation of neurogenesis GO:0050769 165 0.057
oxidation reduction process GO:0055114 304 0.057
reproductive process GO:0022414 372 0.056
purine ribonucleoside metabolic process GO:0046128 168 0.055
sensory organ development GO:0007423 74 0.054
cell projection organization GO:0030030 302 0.054
response to nutrient levels GO:0031667 370 0.054
ion transmembrane transport GO:0034220 365 0.054
response to mineralocorticoid GO:0051385 49 0.054
homeostatic process GO:0042592 331 0.051
chemical homeostasis GO:0048878 292 0.051
negative regulation of metabolic process GO:0009892 331 0.050
anion transport GO:0006820 178 0.050
vesicle mediated transport GO:0016192 181 0.050
organelle organization GO:0006996 266 0.049
positive regulation of transport GO:0051050 245 0.049
regulation of mesenchymal cell proliferation GO:0010464 4 0.049
organic substance catabolic process GO:1901575 316 0.049
response to extracellular stimulus GO:0009991 380 0.048
positive regulation of multicellular organismal process GO:0051240 387 0.047
nucleoside triphosphate catabolic process GO:0009143 123 0.046
response to cytokine GO:0034097 215 0.045
urogenital system development GO:0001655 78 0.044
tube formation GO:0035148 3 0.043
response to hypoxia GO:0001666 231 0.043
single organism catabolic process GO:0044712 283 0.043
multicellular organismal reproductive process GO:0048609 233 0.041
heart growth GO:0060419 20 0.041
regulation of neuron differentiation GO:0045664 208 0.041
response to inorganic substance GO:0010035 377 0.041
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.041
positive regulation of gene expression GO:0010628 244 0.040
positive regulation of ion transport GO:0043270 94 0.040
blood vessel morphogenesis GO:0048514 58 0.040
striated muscle contraction GO:0006941 44 0.039
positive regulation of cell death GO:0010942 184 0.039
response to oxygen levels GO:0070482 265 0.039
regulation of system process GO:0044057 208 0.038
negative regulation of signal transduction GO:0009968 83 0.038
response to oxidative stress GO:0006979 186 0.038
cellular response to glucocorticoid stimulus GO:0071385 68 0.038
cellular amino acid metabolic process GO:0006520 107 0.038
purine ribonucleoside catabolic process GO:0046130 124 0.038
muscle tissue development GO:0060537 58 0.034
apoptotic process GO:0006915 381 0.034
response to decreased oxygen levels GO:0036293 237 0.034
cellular response to lipid GO:0071396 201 0.034
alpha amino acid metabolic process GO:1901605 71 0.034
axis specification GO:0009798 4 0.034
positive regulation of nucleic acid templated transcription GO:1903508 197 0.034
cellular component morphogenesis GO:0032989 155 0.034
regulation of neurogenesis GO:0050767 247 0.034
muscle structure development GO:0061061 87 0.033
positive regulation of signaling GO:0023056 270 0.033
secretion GO:0046903 307 0.033
regulation of cell proliferation GO:0042127 359 0.033
regulation of programmed cell death GO:0043067 341 0.033
cellular chemical homeostasis GO:0055082 247 0.033
small molecule catabolic process GO:0044282 59 0.032
negative regulation of multicellular organismal process GO:0051241 203 0.032
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.031
response to other organism GO:0051707 220 0.031
positive regulation of rna biosynthetic process GO:1902680 197 0.031
negative regulation of biosynthetic process GO:0009890 168 0.031
regulation of anatomical structure morphogenesis GO:0022603 141 0.030
blood circulation GO:0008015 183 0.030
formation of primary germ layer GO:0001704 1 0.030
positive regulation of nervous system development GO:0051962 178 0.030
negative regulation of apoptotic process GO:0043066 181 0.030
negative regulation of cell death GO:0060548 229 0.030
organ morphogenesis GO:0009887 75 0.029
cellular response to stress GO:0033554 269 0.029
embryonic pattern specification GO:0009880 1 0.029
camera type eye development GO:0043010 48 0.029
single organism biosynthetic process GO:0044711 342 0.029
heart morphogenesis GO:0003007 3 0.028
regulation of phosphorylation GO:0042325 248 0.028
cellular response to endogenous stimulus GO:0071495 377 0.028
morphogenesis of embryonic epithelium GO:0016331 3 0.028
negative regulation of cell communication GO:0010648 158 0.028
cellular response to external stimulus GO:0071496 118 0.028
negative regulation of gene expression GO:0010629 199 0.028
neuron differentiation GO:0030182 368 0.028
regulation of molecular function GO:0065009 398 0.027
muscle organ development GO:0007517 50 0.027
neurological system process GO:0050877 219 0.027
response to ketone GO:1901654 182 0.027
blood vessel development GO:0001568 69 0.027
metal ion transport GO:0030001 289 0.026
regulation of cellular component biogenesis GO:0044087 86 0.026
regulation of cellular component organization GO:0051128 368 0.026
cellular response to growth factor stimulus GO:0071363 162 0.026
regulation of secretion by cell GO:1903530 208 0.026
positive regulation of secretion GO:0051047 140 0.026
single organism reproductive process GO:0044702 297 0.026
calcium ion transport GO:0006816 131 0.025
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.025
purine nucleotide catabolic process GO:0006195 136 0.025
carbohydrate derivative metabolic process GO:1901135 346 0.025
mesoderm development GO:0007498 2 0.025
regulation of hormone levels GO:0010817 187 0.025
response to nutrient GO:0007584 248 0.025
response to hexose GO:0009746 144 0.025
multicellular organismal homeostasis GO:0048871 49 0.025
dendrite development GO:0016358 72 0.025
cell morphogenesis involved in differentiation GO:0000904 119 0.025
bmp signaling pathway GO:0030509 4 0.025
regulation of catabolic process GO:0009894 113 0.024
programmed cell death GO:0012501 392 0.024
ribonucleotide catabolic process GO:0009261 136 0.024
connective tissue development GO:0061448 33 0.024
cell cell signaling GO:0007267 335 0.024
cellular response to organic cyclic compound GO:0071407 202 0.024
cell fate determination GO:0001709 2 0.024
response to lipopolysaccharide GO:0032496 191 0.024
reproduction GO:0000003 245 0.024
head development GO:0060322 247 0.024
kidney morphogenesis GO:0060993 13 0.024
central nervous system development GO:0007417 311 0.023
cellular response to oxygen containing compound GO:1901701 386 0.023
cellular macromolecule localization GO:0070727 122 0.023
striated muscle cell development GO:0055002 26 0.023
cellular component biogenesis GO:0044085 368 0.023
regulation of neural precursor cell proliferation GO:2000177 16 0.023
protein complex assembly GO:0006461 263 0.023
respiratory system process GO:0003016 3 0.023
response to wounding GO:0009611 254 0.023
macromolecular complex subunit organization GO:0043933 339 0.023
positive regulation of cellular component organization GO:0051130 200 0.023
response to acid chemical GO:0001101 222 0.023
embryonic axis specification GO:0000578 1 0.023
positive regulation of programmed cell death GO:0043068 157 0.023
hormone secretion GO:0046879 115 0.023
multi multicellular organism process GO:0044706 138 0.023
ribonucleoside metabolic process GO:0009119 174 0.023
purine nucleoside metabolic process GO:0042278 169 0.022
cation transmembrane transport GO:0098655 263 0.022
single organism organelle organization GO:1902589 180 0.022
response to radiation GO:0009314 137 0.022
regulation of ion transport GO:0043269 245 0.022
metal ion homeostasis GO:0055065 186 0.022
response to molecule of bacterial origin GO:0002237 194 0.022
organic acid catabolic process GO:0016054 49 0.022
regulation of cellular catabolic process GO:0031329 101 0.022
embryonic skeletal system morphogenesis GO:0048704 3 0.021
response to light stimulus GO:0009416 52 0.021
embryonic cranial skeleton morphogenesis GO:0048701 2 0.021
organic cyclic compound catabolic process GO:1901361 175 0.021
cellular lipid metabolic process GO:0044255 208 0.021
embryonic skeletal system development GO:0048706 3 0.021
development of primary sexual characteristics GO:0045137 107 0.021
response to toxic substance GO:0009636 133 0.021
aromatic compound catabolic process GO:0019439 168 0.021
cellular ketone metabolic process GO:0042180 51 0.021
reproductive structure development GO:0048608 128 0.021
regulation of cellular component movement GO:0051270 150 0.020
response to growth factor GO:0070848 189 0.020
membrane organization GO:0061024 94 0.020
nucleobase containing compound catabolic process GO:0034655 152 0.020
gastrulation GO:0007369 2 0.020
inorganic ion transmembrane transport GO:0098660 229 0.020
single organism intracellular transport GO:1902582 166 0.020
regulation of body fluid levels GO:0050878 90 0.020
cellular metal ion homeostasis GO:0006875 172 0.020
cellular amine metabolic process GO:0044106 38 0.020
organic hydroxy compound metabolic process GO:1901615 115 0.019
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.019
regulation of cell projection organization GO:0031344 175 0.019
purine nucleoside triphosphate metabolic process GO:0009144 141 0.019
cellular nitrogen compound catabolic process GO:0044270 163 0.019
protein transport GO:0015031 132 0.019
cognition GO:0050890 92 0.019
cellular response to abiotic stimulus GO:0071214 85 0.019
cardiovascular system development GO:0072358 134 0.019
positive regulation of blood circulation GO:1903524 65 0.019
circulatory system process GO:0003013 183 0.019
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.019
ureteric bud development GO:0001657 14 0.019
female pregnancy GO:0007565 122 0.018
neuron projection development GO:0031175 273 0.018
protein complex biogenesis GO:0070271 263 0.018
cell morphogenesis GO:0000902 142 0.018
cellular protein localization GO:0034613 122 0.018
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.018
tube development GO:0035295 89 0.018
cardiac muscle tissue development GO:0048738 26 0.018
spermatogenesis GO:0007283 99 0.018
behavioral response to nicotine GO:0035095 2 0.018
response to fluid shear stress GO:0034405 16 0.018
response to metal ion GO:0010038 253 0.018
positive regulation of cell projection organization GO:0031346 111 0.018
regulation of ion transmembrane transport GO:0034765 121 0.018
response to peptide hormone GO:0043434 278 0.018
Rat
monocarboxylic acid metabolic process GO:0032787 152 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
regulation of vasculature development GO:1901342 44 0.017
cellular modified amino acid metabolic process GO:0006575 61 0.017
heterocycle catabolic process GO:0046700 167 0.017
regulation of stem cell proliferation GO:0072091 14 0.017
regulation of transmembrane transport GO:0034762 122 0.017
neuron development GO:0048666 286 0.016
macromolecular complex assembly GO:0065003 273 0.016
negative regulation of developmental process GO:0051093 125 0.016
regulation of growth GO:0040008 105 0.016
negative regulation of molecular function GO:0044092 133 0.016
response to external biotic stimulus GO:0043207 221 0.016
response to camp GO:0051591 91 0.016
single organism cellular localization GO:1902580 102 0.016
hormone transport GO:0009914 121 0.016
positive regulation of cellular component movement GO:0051272 102 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
cation homeostasis GO:0055080 195 0.016
heart development GO:0007507 72 0.016
regulation of cellular ketone metabolic process GO:0010565 27 0.016
circulatory system development GO:0072359 134 0.016
amine metabolic process GO:0009308 38 0.016
regulation of neuron projection development GO:0010975 161 0.016
protein phosphorylation GO:0006468 345 0.015
anatomical structure formation involved in morphogenesis GO:0048646 83 0.015
regulation of cellular protein metabolic process GO:0032268 267 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
response to mechanical stimulus GO:0009612 134 0.015
nucleoside triphosphate metabolic process GO:0009141 144 0.015
carbohydrate derivative catabolic process GO:1901136 147 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
heart contraction GO:0060047 57 0.015
mesonephric tubule development GO:0072164 14 0.015
muscle cell differentiation GO:0042692 52 0.015
ossification GO:0001503 70 0.015
odontogenesis GO:0042476 32 0.015
regulation of signal transduction GO:0009966 318 0.015
response to dexamethasone GO:0071548 49 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
ribonucleoside triphosphate catabolic process GO:0009203 122 0.014
cellular protein complex assembly GO:0043623 44 0.014
regulation of endocytosis GO:0030100 42 0.014
dendrite morphogenesis GO:0048813 43 0.014
regulation of heart contraction GO:0008016 48 0.014
epithelial tube formation GO:0072175 3 0.014
cellular response to acid chemical GO:0071229 75 0.014
epithelial cell proliferation GO:0050673 54 0.014
adult locomotory behavior GO:0008344 4 0.014
regulation of angiogenesis GO:0045765 39 0.014
grooming behavior GO:0007625 4 0.014
growth GO:0040007 165 0.014
neurotransmitter gated ion channel clustering GO:0072578 3 0.014
nucleotide metabolic process GO:0009117 279 0.014
cellular divalent inorganic cation homeostasis GO:0072503 162 0.014
gamete generation GO:0007276 124 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
organonitrogen compound catabolic process GO:1901565 179 0.013
divalent inorganic cation transport GO:0072511 134 0.013
positive regulation of phosphate metabolic process GO:0045937 262 0.013
metanephric comma shaped body morphogenesis GO:0072278 2 0.013
protein complex subunit organization GO:0071822 302 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
response to biotic stimulus GO:0009607 226 0.013
regulation of dendrite development GO:0050773 59 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
synaptic growth at neuromuscular junction GO:0051124 1 0.013
protein targeting GO:0006605 61 0.013
secretion by cell GO:0032940 248 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.013
positive regulation of secretion by cell GO:1903532 128 0.013
mammary gland epithelium development GO:0061180 1 0.013
regulation of smoothened signaling pathway GO:0008589 2 0.013
regulation of homeostatic process GO:0032844 101 0.013
purine containing compound catabolic process GO:0072523 138 0.013
regulation of nervous system development GO:0051960 264 0.013
regulation of protein kinase activity GO:0045859 105 0.013
regulation of cell growth GO:0001558 85 0.013
sexual reproduction GO:0019953 148 0.013
epithelium development GO:0060429 96 0.013
Rat
proteolysis GO:0006508 175 0.013
regulation of apoptotic process GO:0042981 335 0.013
cell motility GO:0048870 202 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
cellular homeostasis GO:0019725 252 0.013
cellular macromolecular complex assembly GO:0034622 58 0.013
smooth muscle contraction GO:0006939 37 0.013
male gamete generation GO:0048232 99 0.013
regulation of metal ion transport GO:0010959 118 0.013
steroid biosynthetic process GO:0006694 48 0.013
leukocyte cell cell adhesion GO:0007159 4 0.012
cation transport GO:0006812 382 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
ras protein signal transduction GO:0007265 29 0.012
regulation of muscle organ development GO:0048634 26 0.012
regulation of protein metabolic process GO:0051246 289 0.012
appendage morphogenesis GO:0035107 4 0.012
multi organism reproductive process GO:0044703 262 0.012
organic hydroxy compound transport GO:0015850 77 0.012
amide transport GO:0042886 105 0.012
positive regulation of heart contraction GO:0045823 15 0.012
negative regulation of signaling GO:0023057 157 0.012
tonic smooth muscle contraction GO:0014820 4 0.012
regulation of kinase activity GO:0043549 117 0.012
potassium ion transport GO:0006813 97 0.012
regulation of blood circulation GO:1903522 110 0.012
regulation of heart growth GO:0060420 12 0.012
regulation of amine transport GO:0051952 54 0.012
purine ribonucleotide catabolic process GO:0009154 136 0.012
positive regulation of the force of heart contraction by norepinephrine GO:0003061 1 0.012
cardiac muscle tissue growth GO:0055017 20 0.012
gland development GO:0048732 155 0.012
response to reactive oxygen species GO:0000302 120 0.012
mapk cascade GO:0000165 140 0.012
regulation of vesicle mediated transport GO:0060627 81 0.012
regulation of muscle tissue development GO:1901861 25 0.012
nucleotide catabolic process GO:0009166 139 0.012
multicellular organism reproduction GO:0032504 233 0.012
regulation of bmp signaling pathway GO:0030510 2 0.012
sensory perception GO:0007600 101 0.012
organ formation GO:0048645 3 0.012
adenylate cyclase inhibiting serotonin receptor signaling pathway GO:0007198 1 0.011
embryonic epithelial tube formation GO:0001838 3 0.011
cellular cation homeostasis GO:0030003 180 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
negative regulation of transport GO:0051051 136 0.011
regulation of secretion GO:0051046 224 0.011
intracellular transport GO:0046907 185 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.011
cell part morphogenesis GO:0032990 123 0.011
carboxylic acid catabolic process GO:0046395 49 0.011
epithelium migration GO:0090132 19 0.011
cardiac chamber development GO:0003205 1 0.011
inner ear morphogenesis GO:0042472 1 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
cellular response to corticosteroid stimulus GO:0071384 69 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
regulation of organelle organization GO:0033043 80 0.011
sensory perception of pain GO:0019233 73 0.011
regulation of cellular amine metabolic process GO:0033238 8 0.011
response to estrogen GO:0043627 232 0.011
tube morphogenesis GO:0035239 23 0.011
hepaticobiliary system development GO:0061008 90 0.011
heart process GO:0003015 57 0.011
response to interleukin 1 GO:0070555 55 0.011
positive regulation of phosphorus metabolic process GO:0010562 262 0.011
dendritic spine development GO:0060996 20 0.011
divalent metal ion transport GO:0070838 132 0.011
response to bacterium GO:0009617 200 0.011
multicellular organism growth GO:0035264 1 0.011
protein oligomerization GO:0051259 191 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
limb morphogenesis GO:0035108 4 0.011
purine containing compound metabolic process GO:0072521 253 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.010
calcium ion homeostasis GO:0055074 162 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.010
ribonucleoside triphosphate metabolic process GO:0009199 141 0.010
cellular response to carbohydrate stimulus GO:0071322 72 0.010
regulation of striated muscle tissue development GO:0016202 25 0.010
cytoskeleton organization GO:0007010 111 0.010
sex differentiation GO:0007548 113 0.010
single organism behavior GO:0044708 130 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.010
guanosine containing compound catabolic process GO:1901069 71 0.010
organ regeneration GO:0031100 101 0.010
metanephric s shaped body morphogenesis GO:0072284 2 0.010
peptide hormone secretion GO:0030072 84 0.010
memory GO:0007613 54 0.010
organ growth GO:0035265 24 0.010

Crygb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.100
disease of anatomical entity DOID:7 0 0.100
eye disease DOID:5614 0 0.057
eye and adnexa disease DOID:1492 0 0.057
retinal disease DOID:5679 0 0.057
sensory system disease DOID:0050155 0 0.057
retinal degeneration DOID:8466 0 0.057
retinitis pigmentosa DOID:10584 0 0.057
musculoskeletal system disease DOID:17 0 0.032
muscular disease DOID:0080000 0 0.032
muscle tissue disease DOID:66 0 0.032
central nervous system disease DOID:331 0 0.020