Rattus norvegicus

0 known processes

Ctla2a

cytotoxic T lymphocyte-associated protein 2 alpha

(Aliases: RGD1565540)

Ctla2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular component assembly GO:0022607 360 0.216
immune response regulating signaling pathway GO:0002764 19 0.172
cation transport GO:0006812 382 0.166
protein oligomerization GO:0051259 191 0.158
regulation of programmed cell death GO:0043067 341 0.134
immune response GO:0006955 104 0.132
positive regulation of response to stimulus GO:0048584 285 0.124
regulation of immune response GO:0050776 55 0.113
organic acid metabolic process GO:0006082 292 0.100
immune effector process GO:0002252 53 0.100
macromolecular complex subunit organization GO:0043933 339 0.095
cellular metal ion homeostasis GO:0006875 172 0.093
positive regulation of developmental process GO:0051094 283 0.092
lipid metabolic process GO:0006629 283 0.084
regulation of cell proliferation GO:0042127 359 0.081
regulation of apoptotic process GO:0042981 335 0.081
carboxylic acid metabolic process GO:0019752 289 0.078
immune system process GO:0002376 204 0.076
response to nutrient GO:0007584 248 0.074
unsaturated fatty acid metabolic process GO:0033559 39 0.073
positive regulation of immune response GO:0050778 42 0.071
organic acid biosynthetic process GO:0016053 83 0.071
response to inorganic substance GO:0010035 377 0.070
metal ion transport GO:0030001 289 0.069
oxoacid metabolic process GO:0043436 290 0.068
defense response GO:0006952 194 0.067
macromolecular complex assembly GO:0065003 273 0.062
protein complex biogenesis GO:0070271 263 0.061
organ regeneration GO:0031100 101 0.061
regulation of response to stress GO:0080134 126 0.060
cell activation GO:0001775 97 0.060
negative regulation of innate immune response GO:0045824 4 0.058
protein complex subunit organization GO:0071822 302 0.058
cellular amine metabolic process GO:0044106 38 0.057
regulation of cellular localization GO:0060341 263 0.057
protein homooligomerization GO:0051260 91 0.057
programmed cell death GO:0012501 392 0.056
regulation of response to wounding GO:1903034 69 0.054
response to wounding GO:0009611 254 0.052
icosanoid biosynthetic process GO:0046456 18 0.052
wound healing GO:0042060 122 0.051
regulation of immune system process GO:0002682 123 0.051
protein phosphorylation GO:0006468 345 0.049
leukocyte activation GO:0045321 76 0.048
regulation of membrane potential GO:0042391 110 0.048
regulation of ion transport GO:0043269 245 0.048
cellular cation homeostasis GO:0030003 180 0.047
positive regulation of cell proliferation GO:0008284 249 0.046
response to biotic stimulus GO:0009607 226 0.045
natural killer cell mediated immune response to tumor cell GO:0002423 1 0.045
protein complex assembly GO:0006461 263 0.044
lymphocyte activation GO:0046649 43 0.044
central nervous system development GO:0007417 311 0.043
monocarboxylic acid metabolic process GO:0032787 152 0.043
regulation of secretion by cell GO:1903530 208 0.041
response to nutrient levels GO:0031667 370 0.040
response to estrogen GO:0043627 232 0.039
brain development GO:0007420 247 0.039
response to extracellular stimulus GO:0009991 380 0.039
positive regulation of transport GO:0051050 245 0.039
response to reactive oxygen species GO:0000302 120 0.038
amine metabolic process GO:0009308 38 0.038
regulation of metal ion transport GO:0010959 118 0.038
head development GO:0060322 247 0.037
regulation of mast cell activation GO:0033003 9 0.037
icosanoid metabolic process GO:0006690 38 0.037
response to hydrogen peroxide GO:0042542 89 0.037
metal ion homeostasis GO:0055065 186 0.037
fatty acid metabolic process GO:0006631 99 0.036
cardiovascular system development GO:0072358 134 0.035
positive regulation of signaling GO:0023056 270 0.035
carbohydrate derivative metabolic process GO:1901135 346 0.035
cellular divalent inorganic cation homeostasis GO:0072503 162 0.035
nucleobase containing small molecule metabolic process GO:0055086 316 0.034
cellular response to stress GO:0033554 269 0.034
negative regulation of apoptotic process GO:0043066 181 0.033
regulation of signal transduction GO:0009966 318 0.033
vesicle mediated transport GO:0016192 181 0.032
g protein coupled receptor signaling pathway GO:0007186 242 0.032
oxidation reduction process GO:0055114 304 0.032
regulation of hormone levels GO:0010817 187 0.032
response to external biotic stimulus GO:0043207 221 0.031
regulation of cellular ketone metabolic process GO:0010565 27 0.031
apoptotic process GO:0006915 381 0.031
positive regulation of cell communication GO:0010647 271 0.031
calcium ion transport GO:0006816 131 0.031
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.030
regulation of defense response GO:0031347 68 0.030
positive regulation of protein metabolic process GO:0051247 178 0.030
response to vitamin GO:0033273 131 0.030
regulation of cellular protein metabolic process GO:0032268 267 0.030
response to acid chemical GO:0001101 222 0.029
urogenital system development GO:0001655 78 0.029
activation of immune response GO:0002253 26 0.029
positive regulation of programmed cell death GO:0043068 157 0.029
regulation of phosphorylation GO:0042325 248 0.029
leukocyte mediated immunity GO:0002443 28 0.028
carboxylic acid biosynthetic process GO:0046394 83 0.028
regulation of molecular function GO:0065009 398 0.028
cellular chemical homeostasis GO:0055082 247 0.028
cation homeostasis GO:0055080 195 0.028
cellular component biogenesis GO:0044085 368 0.027
positive regulation of immunoglobulin mediated immune response GO:0002891 2 0.027
cellular amino acid metabolic process GO:0006520 107 0.027
positive regulation of multicellular organismal process GO:0051240 387 0.027
single organism biosynthetic process GO:0044711 342 0.026
cellular response to lipid GO:0071396 201 0.026
organophosphate metabolic process GO:0019637 370 0.026
divalent inorganic cation transport GO:0072511 134 0.026
nucleoside phosphate metabolic process GO:0006753 283 0.025
nucleotide metabolic process GO:0009117 279 0.025
positive regulation of defense response GO:0031349 37 0.025
cellular ketone metabolic process GO:0042180 51 0.025
intracellular signal transduction GO:0035556 314 0.024
cellular calcium ion homeostasis GO:0006874 160 0.024
response to cytokine GO:0034097 215 0.024
synaptic transmission GO:0007268 235 0.024
regeneration GO:0031099 163 0.024
divalent metal ion transport GO:0070838 132 0.023
regulation of multicellular organismal development GO:2000026 376 0.023
regulation of rna biosynthetic process GO:2001141 381 0.023
calcium ion homeostasis GO:0055074 162 0.023
response to growth factor GO:0070848 189 0.023
single organism intracellular transport GO:1902582 166 0.023
positive regulation of apoptotic process GO:0043065 154 0.023
proteolysis GO:0006508 175 0.023
cellular response to oxygen containing compound GO:1901701 386 0.022
intracellular transport GO:0046907 185 0.022
positive regulation of immune system process GO:0002684 90 0.022
single organism catabolic process GO:0044712 283 0.022
unsaturated fatty acid biosynthetic process GO:0006636 21 0.022
response to ketone GO:1901654 182 0.022
response to oxygen levels GO:0070482 265 0.022
positive regulation of molecular function GO:0044093 230 0.022
mast cell activation GO:0045576 15 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
monocarboxylic acid biosynthetic process GO:0072330 48 0.021
regulation of calcium ion transport GO:0051924 77 0.021
immune response activating signal transduction GO:0002757 15 0.021
positive regulation of protein modification process GO:0031401 142 0.021
tissue development GO:0009888 252 0.021
regulation of catalytic activity GO:0050790 304 0.021
small molecule biosynthetic process GO:0044283 124 0.020
response to decreased oxygen levels GO:0036293 237 0.020
positive regulation of cell death GO:0010942 184 0.020
response to glucose GO:0009749 136 0.020
purine ribonucleotide metabolic process GO:0009150 227 0.020
purine nucleoside catabolic process GO:0006152 124 0.020
regulation of body fluid levels GO:0050878 90 0.020
heterocycle catabolic process GO:0046700 167 0.019
cellular homeostasis GO:0019725 252 0.019
catabolic process GO:0009056 351 0.019
regulation of cell differentiation GO:0045595 320 0.019
regulation of release of sequestered calcium ion into cytosol GO:0051279 18 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
positive regulation of biosynthetic process GO:0009891 319 0.019
cellular response to extracellular stimulus GO:0031668 73 0.019
lipid biosynthetic process GO:0008610 128 0.019
response to peptide hormone GO:0043434 278 0.019
positive regulation of intracellular signal transduction GO:1902533 138 0.019
cell cell signaling GO:0007267 335 0.019
secretion by cell GO:0032940 248 0.018
reproductive process GO:0022414 372 0.018
single organism organelle organization GO:1902589 180 0.018
response to mechanical stimulus GO:0009612 134 0.018
natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002420 1 0.018
cellular response to hormone stimulus GO:0032870 247 0.018
negative regulation of programmed cell death GO:0043069 183 0.018
anatomical structure formation involved in morphogenesis GO:0048646 83 0.018
anatomical structure morphogenesis GO:0009653 298 0.018
ribonucleoside metabolic process GO:0009119 174 0.018
regulation of protein metabolic process GO:0051246 289 0.018
cellular lipid metabolic process GO:0044255 208 0.018
blood vessel development GO:0001568 69 0.018
fatty acid biosynthetic process GO:0006633 33 0.017
cellular response to nutrient levels GO:0031669 60 0.017
hepaticobiliary system development GO:0061008 90 0.017
cytosolic calcium ion homeostasis GO:0051480 140 0.017
response to hypoxia GO:0001666 231 0.017
ribonucleoside triphosphate metabolic process GO:0009199 141 0.017
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.017
inflammatory response GO:0006954 150 0.017
regulation of secretion GO:0051046 224 0.017
secretion GO:0046903 307 0.017
neurological system process GO:0050877 219 0.017
protein homotrimerization GO:0070207 15 0.017
peptidyl amino acid modification GO:0018193 126 0.017
response to tumor cell GO:0002347 4 0.017
positive regulation of cellular component organization GO:0051130 200 0.016
response to corticosteroid GO:0031960 235 0.016
cellular catabolic process GO:0044248 295 0.016
calcium ion transport into cytosol GO:0060402 38 0.016
rna metabolic process GO:0016070 406 0.016
negative regulation of response to stimulus GO:0048585 155 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
regulation of natural killer cell mediated immunity GO:0002715 6 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.016
aging GO:0007568 241 0.016
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.016
organonitrogen compound catabolic process GO:1901565 179 0.015
b cell mediated immunity GO:0019724 4 0.015
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.015
ribose phosphate metabolic process GO:0019693 235 0.015
myeloid leukocyte activation GO:0002274 36 0.015
response to carbohydrate GO:0009743 183 0.015
regulation of response to external stimulus GO:0032101 106 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
purine ribonucleotide catabolic process GO:0009154 136 0.015
negative regulation of molecular function GO:0044092 133 0.015
ion homeostasis GO:0050801 212 0.015
regulation of smooth muscle cell proliferation GO:0048660 75 0.015
regulation of cellular component organization GO:0051128 368 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
hemostasis GO:0007599 26 0.015
response to calcium ion GO:0051592 59 0.015
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
natural killer cell mediated immunity GO:0002228 6 0.014
response to glucocorticoid GO:0051384 223 0.014
positive regulation of leukocyte degranulation GO:0043302 4 0.014
regulation of homeostatic process GO:0032844 101 0.014
vasculogenesis GO:0001570 3 0.014
smooth muscle cell proliferation GO:0048659 77 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
regulated secretory pathway GO:0045055 17 0.014
ribonucleotide metabolic process GO:0009259 231 0.014
purine ribonucleoside catabolic process GO:0046130 124 0.014
purine containing compound metabolic process GO:0072521 253 0.014
innate immune response GO:0045087 35 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
positive regulation of secretion by cell GO:1903532 128 0.014
nucleotide catabolic process GO:0009166 139 0.014
gland development GO:0048732 155 0.014
organophosphate catabolic process GO:0046434 148 0.014
regulation of cell activation GO:0050865 50 0.013
alpha beta t cell differentiation GO:0046632 2 0.013
peptidyl tyrosine modification GO:0018212 72 0.013
endocytosis GO:0006897 84 0.013
amide transport GO:0042886 105 0.013
regulation of transferase activity GO:0051338 123 0.013
membrane organization GO:0061024 94 0.013
regulation of innate immune response GO:0045088 15 0.013
epithelium development GO:0060429 96 0.013
receptor mediated endocytosis GO:0006898 42 0.013
rna biosynthetic process GO:0032774 380 0.013
reactive nitrogen species metabolic process GO:2001057 1 0.013
homeostatic process GO:0042592 331 0.013
regulation of alpha beta t cell activation GO:0046634 2 0.013
tube development GO:0035295 89 0.013
regulation of leukocyte activation GO:0002694 45 0.013
cellular response to biotic stimulus GO:0071216 59 0.013
negative regulation of metabolic process GO:0009892 331 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
glycosyl compound catabolic process GO:1901658 126 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
peptidyl tyrosine phosphorylation GO:0018108 72 0.013
ribonucleoside catabolic process GO:0042454 126 0.013
cytoplasmic transport GO:0016482 115 0.012
gliogenesis GO:0042063 93 0.012
cellular component movement GO:0006928 248 0.012
establishment of protein localization GO:0045184 141 0.012
alpha beta t cell activation GO:0046631 3 0.012
growth GO:0040007 165 0.012
protein heterooligomerization GO:0051291 89 0.012
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002859 1 0.012
response to estradiol GO:0032355 164 0.012
response to ethanol GO:0045471 162 0.012
organonitrogen compound biosynthetic process GO:1901566 167 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
regulation of protein modification process GO:0031399 194 0.012
negative regulation of cell death GO:0060548 229 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
cellular component morphogenesis GO:0032989 155 0.012
nucleoside metabolic process GO:0009116 179 0.012
sequestering of calcium ion GO:0051208 8 0.012
response to hexose GO:0009746 144 0.012
response to peptide GO:1901652 292 0.012
positive regulation of signal transduction GO:0009967 175 0.011
biological adhesion GO:0022610 110 0.011
response to monosaccharide GO:0034284 159 0.011
cellular ion homeostasis GO:0006873 184 0.011
transmembrane transport GO:0055085 412 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.011
kidney development GO:0001822 67 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
nitrogen compound transport GO:0071705 229 0.011
sensory perception of pain GO:0019233 73 0.011
response to lipopolysaccharide GO:0032496 191 0.011
cellular response to endogenous stimulus GO:0071495 377 0.011
cellular response to reactive oxygen species GO:0034614 55 0.011
positive regulation of secretion GO:0051047 140 0.011
regulation of stress activated mapk cascade GO:0032872 23 0.011
organic substance catabolic process GO:1901575 316 0.011
regulation of catabolic process GO:0009894 113 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
response to oxidative stress GO:0006979 186 0.011
coagulation GO:0050817 28 0.011
localization of cell GO:0051674 202 0.011
lymphocyte mediated immunity GO:0002449 14 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
peptide transport GO:0015833 97 0.011
purine nucleoside triphosphate catabolic process GO:0009146 122 0.011
reproductive structure development GO:0048608 128 0.011
positive regulation of phosphorus metabolic process GO:0010562 262 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
locomotion GO:0040011 237 0.011
fc epsilon receptor signaling pathway GO:0038095 1 0.011
blood coagulation GO:0007596 26 0.010
response to transition metal nanoparticle GO:1990267 122 0.010
cellular nitrogen compound catabolic process GO:0044270 163 0.010
cytolysis GO:0019835 4 0.010
regulation of transcription dna templated GO:0006355 374 0.010
reactive oxygen species metabolic process GO:0072593 37 0.010
macromolecule localization GO:0033036 252 0.010
positive regulation of phosphorylation GO:0042327 177 0.010

Ctla2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.016
disease of anatomical entity DOID:7 0 0.016
hematopoietic system disease DOID:74 0 0.016