Rattus norvegicus

7 known processes

Ctrl

chymotrypsin-like

Ctrl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
programmed cell death GO:0012501 392 0.432
Rat
regulation of programmed cell death GO:0043067 341 0.235
Rat
metal ion transport GO:0030001 289 0.232
regulation of cell projection organization GO:0031344 175 0.219
regulation of neurogenesis GO:0050767 247 0.217
positive regulation of neurogenesis GO:0050769 165 0.182
response to cytokine GO:0034097 215 0.171
Rat
apoptotic process GO:0006915 381 0.166
Rat
tissue development GO:0009888 252 0.154
regulation of cellular component organization GO:0051128 368 0.150
regulation of cell differentiation GO:0045595 320 0.145
regulation of neuron differentiation GO:0045664 208 0.144
regulation of nervous system development GO:0051960 264 0.144
nucleic acid templated transcription GO:0097659 379 0.138
positive regulation of multicellular organismal process GO:0051240 387 0.128
regulation of multicellular organismal development GO:2000026 376 0.128
regulation of apoptotic process GO:0042981 335 0.127
Rat
locomotion GO:0040011 237 0.127
positive regulation of nervous system development GO:0051962 178 0.126
regulation of neuron projection development GO:0010975 161 0.116
regulation of membrane potential GO:0042391 110 0.109
negative regulation of cell death GO:0060548 229 0.108
regulation of rna metabolic process GO:0051252 391 0.106
neuron differentiation GO:0030182 368 0.098
regulation of locomotion GO:0040012 148 0.096
transmembrane transport GO:0055085 412 0.095
negative regulation of signaling GO:0023057 157 0.095
response to extracellular stimulus GO:0009991 380 0.093
Rat
central nervous system development GO:0007417 311 0.093
brain development GO:0007420 247 0.092
organic substance catabolic process GO:1901575 316 0.091
Rat
cellular response to endogenous stimulus GO:0071495 377 0.090
ion transmembrane transport GO:0034220 365 0.084
regulation of system process GO:0044057 208 0.084
positive regulation of neuron projection development GO:0010976 99 0.084
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.082
macromolecular complex assembly GO:0065003 273 0.082
response to nutrient GO:0007584 248 0.081
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.081
neurological system process GO:0050877 219 0.077
transcription dna templated GO:0006351 377 0.077
cell projection organization GO:0030030 302 0.077
cation transmembrane transport GO:0098655 263 0.076
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.076
positive regulation of cell death GO:0010942 184 0.075
Rat
organic acid metabolic process GO:0006082 292 0.073
regulation of cell development GO:0060284 263 0.070
head development GO:0060322 247 0.069
secretion GO:0046903 307 0.068
response to hypoxia GO:0001666 231 0.068
response to acid chemical GO:0001101 222 0.068
regulation of transcription dna templated GO:0006355 374 0.066
neuron projection development GO:0031175 273 0.066
neuron death GO:0070997 127 0.066
cellular amine metabolic process GO:0044106 38 0.066
response to peptide hormone GO:0043434 278 0.066
Rat
neuron development GO:0048666 286 0.065
regulation of signal transduction GO:0009966 318 0.065
cellular amino acid metabolic process GO:0006520 107 0.062
rna metabolic process GO:0016070 406 0.061
positive regulation of cellular component organization GO:0051130 200 0.061
negative regulation of programmed cell death GO:0043069 183 0.060
protein complex biogenesis GO:0070271 263 0.060
cell type specific apoptotic process GO:0097285 134 0.059
oxoacid metabolic process GO:0043436 290 0.057
cellular response to stress GO:0033554 269 0.057
positive regulation of nucleic acid templated transcription GO:1903508 197 0.055
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.055
rhythmic process GO:0048511 156 0.055
regulation of molecular function GO:0065009 398 0.055
cation transport GO:0006812 382 0.054
positive regulation of apoptotic process GO:0043065 154 0.054
Rat
response to glucocorticoid GO:0051384 223 0.052
response to nutrient levels GO:0031667 370 0.052
Rat
response to purine containing compound GO:0014074 126 0.052
negative regulation of apoptotic process GO:0043066 181 0.052
cellular response to oxygen containing compound GO:1901701 386 0.051
positive regulation of cell projection organization GO:0031346 111 0.051
homeostatic process GO:0042592 331 0.050
positive regulation of gene expression GO:0010628 244 0.050
regulation of rna biosynthetic process GO:2001141 381 0.049
negative regulation of multicellular organismal process GO:0051241 203 0.049
carboxylic acid metabolic process GO:0019752 289 0.048
synaptic transmission GO:0007268 235 0.047
cellular component assembly GO:0022607 360 0.047
response to decreased oxygen levels GO:0036293 237 0.047
cell projection morphogenesis GO:0048858 123 0.046
amine metabolic process GO:0009308 38 0.046
neuron apoptotic process GO:0051402 88 0.045
positive regulation of rna metabolic process GO:0051254 203 0.045
behavior GO:0007610 205 0.045
protein phosphorylation GO:0006468 345 0.045
intracellular transport GO:0046907 185 0.045
regulation of nucleic acid templated transcription GO:1903506 380 0.045
catabolic process GO:0009056 351 0.044
Rat
regulation of secretion by cell GO:1903530 208 0.044
positive regulation of cell proliferation GO:0008284 249 0.044
response to growth factor GO:0070848 189 0.043
regulation of cell proliferation GO:0042127 359 0.043
regulation of ion transport GO:0043269 245 0.042
protein localization GO:0008104 191 0.042
positive regulation of transport GO:0051050 245 0.042
negative regulation of cell communication GO:0010648 158 0.041
regulation of cell motility GO:2000145 131 0.041
negative regulation of cellular metabolic process GO:0031324 281 0.040
reproduction GO:0000003 245 0.040
vesicle mediated transport GO:0016192 181 0.040
localization of cell GO:0051674 202 0.040
neuron neuron synaptic transmission GO:0007270 60 0.040
response to inorganic substance GO:0010035 377 0.039
regulation of phosphate metabolic process GO:0019220 349 0.039
response to peptide GO:1901652 292 0.039
Rat
protein complex assembly GO:0006461 263 0.039
transcription from rna polymerase ii promoter GO:0006366 252 0.039
cellular ketone metabolic process GO:0042180 51 0.038
calcium ion transport GO:0006816 131 0.038
cellular response to hormone stimulus GO:0032870 247 0.038
response to alkaloid GO:0043279 132 0.038
positive regulation of programmed cell death GO:0043068 157 0.037
Rat
anatomical structure morphogenesis GO:0009653 298 0.036
response to camp GO:0051591 91 0.035
positive regulation of cell migration GO:0030335 96 0.035
negative regulation of response to stimulus GO:0048585 155 0.035
cellular response to tumor necrosis factor GO:0071356 46 0.034
cell cell signaling GO:0007267 335 0.034
organic acid transport GO:0015849 116 0.034
intracellular signal transduction GO:0035556 314 0.033
cellular chemical homeostasis GO:0055082 247 0.033
single organism intracellular transport GO:1902582 166 0.033
regulation of cellular amine metabolic process GO:0033238 8 0.033
positive regulation of cellular biosynthetic process GO:0031328 295 0.032
positive regulation of biosynthetic process GO:0009891 319 0.032
response to wounding GO:0009611 254 0.032
carbohydrate derivative metabolic process GO:1901135 346 0.032
negative regulation of biosynthetic process GO:0009890 168 0.031
monovalent inorganic cation transport GO:0015672 172 0.031
positive regulation of cell development GO:0010720 176 0.031
response to mechanical stimulus GO:0009612 134 0.031
secretion by cell GO:0032940 248 0.031
cellular response to cytokine stimulus GO:0071345 127 0.031
response to toxic substance GO:0009636 133 0.031
Rat
cellular homeostasis GO:0019725 252 0.031
calcium ion transport into cytosol GO:0060402 38 0.030
sensory organ development GO:0007423 74 0.030
negative regulation of neurogenesis GO:0050768 78 0.030
anion transport GO:0006820 178 0.030
response to ketone GO:1901654 182 0.029
negative regulation of macromolecule metabolic process GO:0010605 260 0.029
regulation of cell migration GO:0030334 128 0.029
immune system process GO:0002376 204 0.029
response to nicotine GO:0035094 51 0.028
growth GO:0040007 165 0.028
cell morphogenesis GO:0000902 142 0.028
inorganic cation transmembrane transport GO:0098662 202 0.028
positive regulation of secretion by cell GO:1903532 128 0.027
macromolecular complex subunit organization GO:0043933 339 0.027
positive regulation of cellular amine metabolic process GO:0033240 3 0.027
cellular response to organonitrogen compound GO:0071417 197 0.027
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.027
response to oxidative stress GO:0006979 186 0.027
positive regulation of rna biosynthetic process GO:1902680 197 0.026
negative regulation of cell development GO:0010721 82 0.026
protein complex subunit organization GO:0071822 302 0.026
regeneration GO:0031099 163 0.026
divalent inorganic cation homeostasis GO:0072507 165 0.026
circadian rhythm GO:0007623 88 0.026
negative regulation of metabolic process GO:0009892 331 0.026
chemical homeostasis GO:0048878 292 0.026
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.026
cellular component movement GO:0006928 248 0.025
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.025
neuron projection morphogenesis GO:0048812 122 0.025
muscle contraction GO:0006936 88 0.025
single organism reproductive process GO:0044702 297 0.025
protein maturation GO:0051604 68 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
signal release GO:0023061 145 0.025
cellular catabolic process GO:0044248 295 0.024
cellular calcium ion homeostasis GO:0006874 160 0.024
single organism biosynthetic process GO:0044711 342 0.024
response to metal ion GO:0010038 253 0.023
cellular response to organic cyclic compound GO:0071407 202 0.023
organelle organization GO:0006996 266 0.023
regulation of secretion GO:0051046 224 0.023
positive regulation of developmental process GO:0051094 283 0.022
positive regulation of catalytic activity GO:0043085 184 0.022
rna biosynthetic process GO:0032774 380 0.022
regulation of response to stress GO:0080134 126 0.022
macromolecule localization GO:0033036 252 0.022
positive regulation of cell differentiation GO:0045597 217 0.022
negative regulation of gene expression GO:0010629 199 0.022
negative regulation of cellular biosynthetic process GO:0031327 161 0.022
cell migration GO:0016477 197 0.021
cellular cation homeostasis GO:0030003 180 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.021
ras protein signal transduction GO:0007265 29 0.021
cellular response to nitrogen compound GO:1901699 210 0.021
eye development GO:0001654 50 0.021
multicellular organismal reproductive process GO:0048609 233 0.021
positive regulation of neuron differentiation GO:0045666 126 0.021
cellular response to lipid GO:0071396 201 0.021
regulation of cellular protein metabolic process GO:0032268 267 0.021
cytoplasmic transport GO:0016482 115 0.021
regulation of protein modification process GO:0031399 194 0.021
positive regulation of ion transport GO:0043270 94 0.021
regulation of metal ion transport GO:0010959 118 0.020
positive regulation of cytoskeleton organization GO:0051495 26 0.020
neuron fate commitment GO:0048663 4 0.020
synapse organization GO:0050808 46 0.020
camera type eye development GO:0043010 48 0.020
ion homeostasis GO:0050801 212 0.020
negative regulation of protein metabolic process GO:0051248 114 0.019
regulation of protein metabolic process GO:0051246 289 0.019
cellular divalent inorganic cation homeostasis GO:0072503 162 0.019
cellular response to insulin stimulus GO:0032869 81 0.019
positive regulation of secretion GO:0051047 140 0.019
response to food GO:0032094 27 0.019
Rat
proteolysis GO:0006508 175 0.019
regulation of cellular localization GO:0060341 263 0.019
response to other organism GO:0051707 220 0.018
response to tumor necrosis factor GO:0034612 56 0.018
nucleobase containing small molecule metabolic process GO:0055086 316 0.018
positive regulation of molecular function GO:0044093 230 0.018
calcium ion homeostasis GO:0055074 162 0.018
cellular component morphogenesis GO:0032989 155 0.018
response to transition metal nanoparticle GO:1990267 122 0.018
cell part morphogenesis GO:0032990 123 0.018
amino acid transport GO:0006865 70 0.018
negative regulation of rna biosynthetic process GO:1902679 118 0.018
ribose phosphate metabolic process GO:0019693 235 0.017
cation homeostasis GO:0055080 195 0.017
learning or memory GO:0007611 90 0.017
response to electrical stimulus GO:0051602 56 0.017
regulation of catalytic activity GO:0050790 304 0.017
divalent inorganic cation transport GO:0072511 134 0.017
positive regulation of cell communication GO:0010647 271 0.017
inorganic ion transmembrane transport GO:0098660 229 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
regulation of transmembrane transport GO:0034762 122 0.017
cellular protein localization GO:0034613 122 0.017
regulation of cellular component biogenesis GO:0044087 86 0.017
synaptic growth at neuromuscular junction GO:0051124 1 0.017
myeloid leukocyte activation GO:0002274 36 0.017
regulation of reactive oxygen species metabolic process GO:2000377 26 0.016
cellular component biogenesis GO:0044085 368 0.016
reproductive process GO:0022414 372 0.016
negative regulation of nervous system development GO:0051961 79 0.016
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.016
regulation of dna metabolic process GO:0051052 60 0.016
regulation of cell morphogenesis GO:0022604 77 0.016
cell growth GO:0016049 104 0.016
response to organophosphorus GO:0046683 102 0.016
regulation of neuron apoptotic process GO:0043523 83 0.016
negative regulation of developmental process GO:0051093 125 0.016
action potential GO:0001508 54 0.016
negative regulation of cell differentiation GO:0045596 99 0.016
positive regulation of transcription dna templated GO:0045893 197 0.016
calcium ion transmembrane transport GO:0070588 70 0.016
cell motility GO:0048870 202 0.015
cellular ion homeostasis GO:0006873 184 0.015
epithelium development GO:0060429 96 0.015
muscle system process GO:0003012 115 0.015
multicellular organism reproduction GO:0032504 233 0.015
positive regulation of protein modification process GO:0031401 142 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
regulation of phosphorylation GO:0042325 248 0.015
response to oxygen levels GO:0070482 265 0.015
response to lipopolysaccharide GO:0032496 191 0.015
regulation of neuron death GO:1901214 115 0.015
sequestering of metal ion GO:0051238 9 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
response to corticosterone GO:0051412 40 0.015
urogenital system development GO:0001655 78 0.014
leukocyte activation GO:0045321 76 0.014
single organism behavior GO:0044708 130 0.014
palate development GO:0060021 2 0.014
regulation of anatomical structure morphogenesis GO:0022603 141 0.014
single organism organelle organization GO:1902589 180 0.014
response to radiation GO:0009314 137 0.014
negative regulation of transport GO:0051051 136 0.014
response to osmotic stress GO:0006970 42 0.014
nucleotide metabolic process GO:0009117 279 0.014
mononuclear cell proliferation GO:0032943 29 0.014
cellular macromolecular complex assembly GO:0034622 58 0.014
response to carbohydrate GO:0009743 183 0.014
spinal cord development GO:0021510 27 0.014
negative regulation of hormone secretion GO:0046888 46 0.014
negative regulation of transcription dna templated GO:0045892 116 0.014
single organism catabolic process GO:0044712 283 0.014
ribonucleotide metabolic process GO:0009259 231 0.014
negative regulation of rna metabolic process GO:0051253 123 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
aging GO:0007568 241 0.014
regulation of synaptic plasticity GO:0048167 70 0.014
forebrain development GO:0030900 98 0.014
cytosolic calcium ion transport GO:0060401 39 0.014
aromatic compound catabolic process GO:0019439 168 0.014
sensory perception GO:0007600 101 0.013
gliogenesis GO:0042063 93 0.013
positive regulation of response to stimulus GO:0048584 285 0.013
cytoskeleton organization GO:0007010 111 0.013
regulation of cell growth GO:0001558 85 0.013
dendrite development GO:0016358 72 0.013
lymphocyte proliferation GO:0046651 29 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
reactive nitrogen species metabolic process GO:2001057 1 0.013
memory GO:0007613 54 0.013
protein autophosphorylation GO:0046777 66 0.013
divalent metal ion transport GO:0070838 132 0.013
regulation of ion transmembrane transport GO:0034765 121 0.013
regulation of anatomical structure size GO:0090066 135 0.013
purine ribonucleoside metabolic process GO:0046128 168 0.013
regulation of cellular component size GO:0032535 51 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
response to activity GO:0014823 73 0.013
negative regulation of cellular component organization GO:0051129 83 0.012
positive regulation of cell motility GO:2000147 97 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
establishment of protein localization GO:0045184 141 0.012
nitrogen compound transport GO:0071705 229 0.012
axon development GO:0061564 96 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
response to monosaccharide GO:0034284 159 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
plasma lipoprotein particle clearance GO:0034381 3 0.012
acid secretion GO:0046717 48 0.012
organ morphogenesis GO:0009887 75 0.012
adult locomotory behavior GO:0008344 4 0.012
cellular response to monosaccharide stimulus GO:0071326 67 0.012
mapk cascade GO:0000165 140 0.012
circulatory system process GO:0003013 183 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
cellular protein complex assembly GO:0043623 44 0.012
endocytosis GO:0006897 84 0.012
cellular response to oxygen levels GO:0071453 60 0.012
sex differentiation GO:0007548 113 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
cyclic nucleotide metabolic process GO:0009187 80 0.011
single organism cellular localization GO:1902580 102 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
carboxylic acid biosynthetic process GO:0046394 83 0.011
regulation of intracellular signal transduction GO:1902531 218 0.011
protein transport GO:0015031 132 0.011
blood circulation GO:0008015 183 0.011
kidney development GO:0001822 67 0.011
neuromuscular process GO:0050905 2 0.011
negative regulation of cell projection organization GO:0031345 50 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
biological adhesion GO:0022610 110 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
cellular response to external stimulus GO:0071496 118 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
organ regeneration GO:0031100 101 0.011
amide transport GO:0042886 105 0.011
response to temperature stimulus GO:0009266 94 0.011
protein catabolic process GO:0030163 30 0.011
Rat
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
negative regulation of molecular function GO:0044092 133 0.011
cellular response to growth factor stimulus GO:0071363 162 0.011
organophosphate catabolic process GO:0046434 148 0.011
regulation of cytoskeleton organization GO:0051493 49 0.011
protein oligomerization GO:0051259 191 0.010
heterocycle catabolic process GO:0046700 167 0.010
defense response GO:0006952 194 0.010
carbohydrate derivative catabolic process GO:1901136 147 0.010
regulation of protein processing GO:0070613 50 0.010
positive regulation of intracellular signal transduction GO:1902533 138 0.010
ovulation cycle GO:0042698 67 0.010
axis specification GO:0009798 4 0.010
response to molecule of bacterial origin GO:0002237 194 0.010
peptidyl amino acid modification GO:0018193 126 0.010
regulation of response to external stimulus GO:0032101 106 0.010
regulation of phosphorus metabolic process GO:0051174 349 0.010
regulation of canonical wnt signaling pathway GO:0060828 4 0.010

Ctrl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.078
nervous system disease DOID:863 0 0.078
central nervous system disease DOID:331 0 0.022
musculoskeletal system disease DOID:17 0 0.011
connective tissue disease DOID:65 0 0.011
bone disease DOID:0080001 0 0.011