Rattus norvegicus

0 known processes

Ctsa

cathepsin A

(Aliases: Ppgb)

Ctsa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.347
proteolysis GO:0006508 175 0.135
phenylpropanoid catabolic process GO:0046271 3 0.130
autophagic cell death GO:0048102 4 0.108
regulation of programmed cell death GO:0043067 341 0.107
single organism reproductive process GO:0044702 297 0.087
reproductive process GO:0022414 372 0.084
catabolic process GO:0009056 351 0.078
organic acid metabolic process GO:0006082 292 0.065
apoptotic process GO:0006915 381 0.061
monocarboxylic acid metabolic process GO:0032787 152 0.059
programmed cell death GO:0012501 392 0.059
regulation of tolerance induction to nonself antigen GO:0002655 1 0.054
cellular lipid metabolic process GO:0044255 208 0.053
multi organism reproductive process GO:0044703 262 0.046
response to nutrient levels GO:0031667 370 0.045
negative regulation of cell death GO:0060548 229 0.043
cellular catabolic process GO:0044248 295 0.043
peptide metabolic process GO:0006518 32 0.042
aging GO:0007568 241 0.041
regulation of hormone levels GO:0010817 187 0.041
head development GO:0060322 247 0.040
lipid metabolic process GO:0006629 283 0.039
multicellular organismal reproductive process GO:0048609 233 0.039
multi multicellular organism process GO:0044706 138 0.036
response to other organism GO:0051707 220 0.035
hormone metabolic process GO:0042445 69 0.035
response to estrogen GO:0043627 232 0.035
carboxylic acid metabolic process GO:0019752 289 0.034
cellular amide metabolic process GO:0043603 44 0.033
positive regulation of cellular component organization GO:0051130 200 0.032
positive regulation of signaling GO:0023056 270 0.031
peptide catabolic process GO:0043171 5 0.030
cellular response to endogenous stimulus GO:0071495 377 0.029
neuron projection development GO:0031175 273 0.029
positive regulation of nervous system development GO:0051962 178 0.029
response to cytokine GO:0034097 215 0.028
cellular hormone metabolic process GO:0034754 49 0.028
positive regulation of multicellular organismal process GO:0051240 387 0.027
keratan sulfate metabolic process GO:0042339 1 0.026
regulation of apoptotic process GO:0042981 335 0.026
female pregnancy GO:0007565 122 0.026
regulation of bmp signaling pathway GO:0030510 2 0.025
peptidyl glutamic acid modification GO:0018200 1 0.025
amine metabolic process GO:0009308 38 0.025
positive regulation of apoptotic process GO:0043065 154 0.025
terpenoid metabolic process GO:0006721 37 0.024
positive regulation of developmental process GO:0051094 283 0.024
sexual reproduction GO:0019953 148 0.023
sulfur compound catabolic process GO:0044273 3 0.023
chemical homeostasis GO:0048878 292 0.023
immune system process GO:0002376 204 0.023
regulation of multicellular organismal development GO:2000026 376 0.022
macromolecule catabolic process GO:0009057 58 0.021
secretion GO:0046903 307 0.020
cell cell signaling GO:0007267 335 0.020
defense response GO:0006952 194 0.020
regulation of neuron differentiation GO:0045664 208 0.020
antigen processing and presentation of peptide antigen GO:0048002 2 0.020
positive regulation of signal transduction GO:0009967 175 0.020
positive regulation of cell differentiation GO:0045597 217 0.020
positive regulation of cell development GO:0010720 176 0.019
tetrapyrrole metabolic process GO:0033013 11 0.019
carbohydrate derivative metabolic process GO:1901135 346 0.019
multicellular organism reproduction GO:0032504 233 0.019
isoprenoid metabolic process GO:0006720 45 0.019
cellular amino acid metabolic process GO:0006520 107 0.019
response to peptide hormone GO:0043434 278 0.018
regeneration GO:0031099 163 0.018
response to biotic stimulus GO:0009607 226 0.018
negative regulation of striated muscle cell differentiation GO:0051154 2 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.018
response to external biotic stimulus GO:0043207 221 0.017
regulation of peptidase activity GO:0052547 55 0.017
response to nutrient GO:0007584 248 0.017
regulation of blood pressure GO:0008217 83 0.017
regulation of neurogenesis GO:0050767 247 0.017
diterpenoid metabolic process GO:0016101 33 0.017
multicellular organismal catabolic process GO:0044243 2 0.016
positive regulation of neuron projection development GO:0010976 99 0.016
regulation of molecular function GO:0065009 398 0.016
neuron development GO:0048666 286 0.016
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.016
positive regulation of programmed cell death GO:0043068 157 0.016
protein phosphorylation GO:0006468 345 0.016
cellular response to hormone stimulus GO:0032870 247 0.016
response to extracellular stimulus GO:0009991 380 0.015
positive regulation of cell projection organization GO:0031346 111 0.015
axonogenesis GO:0007409 71 0.015
gland development GO:0048732 155 0.015
regulation of cell differentiation GO:0045595 320 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
vesicle mediated transport GO:0016192 181 0.014
regulation of anatomical structure size GO:0090066 135 0.014
response to carbohydrate GO:0009743 183 0.014
response to acid chemical GO:0001101 222 0.014
response to glucocorticoid GO:0051384 223 0.014
organic substance catabolic process GO:1901575 316 0.014
synaptic vesicle endocytosis GO:0048488 4 0.014
positive regulation of neurogenesis GO:0050769 165 0.014
cellular response to stress GO:0033554 269 0.014
developmental growth GO:0048589 100 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
reproduction GO:0000003 245 0.013
regulation of cell development GO:0060284 263 0.013
response to purine containing compound GO:0014074 126 0.013
regulation of angiotensin levels in blood GO:0002002 2 0.013
carbohydrate metabolic process GO:0005975 130 0.013
regulation of neuron projection development GO:0010975 161 0.013
response to amine GO:0014075 46 0.013
gamete generation GO:0007276 124 0.012
response to monosaccharide GO:0034284 159 0.012
response to estradiol GO:0032355 164 0.012
regulation of signal transduction GO:0009966 318 0.012
cell projection organization GO:0030030 302 0.012
endocytosis GO:0006897 84 0.012
response to testosterone GO:0033574 55 0.012
amino sugar metabolic process GO:0006040 12 0.012
hexose catabolic process GO:0019320 10 0.012
cell cell signaling involved in cell fate commitment GO:0045168 2 0.012
regulation of protein metabolic process GO:0051246 289 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
bmp signaling pathway GO:0030509 4 0.011
response to ketone GO:1901654 182 0.011
regulation of body fluid levels GO:0050878 90 0.011
response to peptide GO:1901652 292 0.011
monosaccharide metabolic process GO:0005996 61 0.011
developmental process involved in reproduction GO:0003006 159 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
proximal distal pattern formation GO:0009954 1 0.011
innate immune response GO:0045087 35 0.011
reproductive system development GO:0061458 128 0.010
response to cgmp GO:0070305 3 0.010
cellular response to oxygen containing compound GO:1901701 386 0.010
response to toxic substance GO:0009636 133 0.010
respiratory system development GO:0060541 45 0.010
anatomical structure morphogenesis GO:0009653 298 0.010
regulation of endopeptidase activity GO:0052548 51 0.010
synaptic transmission GO:0007268 235 0.010

Ctsa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
inherited metabolic disorder DOID:655 0 0.925
lysosomal storage disease DOID:3211 0 0.925
disease of metabolism DOID:0014667 0 0.925
lipid storage disease DOID:9455 0 0.813
sphingolipidosis DOID:1927 0 0.268
nervous system disease DOID:863 0 0.224
disease of anatomical entity DOID:7 0 0.224
central nervous system disease DOID:331 0 0.077
brain disease DOID:936 0 0.074
cerebral degeneration DOID:1443 0 0.074
age related macular degeneration DOID:10871 0 0.020
eye disease DOID:5614 0 0.020
degeneration of macula and posterior pole DOID:2007 0 0.020
macular degeneration DOID:4448 0 0.020
eye and adnexa disease DOID:1492 0 0.020
sensory system disease DOID:0050155 0 0.020
retinal disease DOID:5679 0 0.020
retinal degeneration DOID:8466 0 0.020
hematopoietic system disease DOID:74 0 0.013
immune system disease DOID:2914 0 0.013
blood protein disease DOID:620 0 0.013