Rattus norvegicus

16 known processes

Cyp24a1

cytochrome P450, family 24, subfamily a, polypeptide 1

(Aliases: 25-hydroxyvitaminD324-hydroxylase,VITD12,Cyp24)

Cyp24a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.182
Rat
organic acid metabolic process GO:0006082 292 0.126
Rat
cellular response to hormone stimulus GO:0032870 247 0.100
Rat
lipid metabolic process GO:0006629 283 0.098
cellular response to endogenous stimulus GO:0071495 377 0.080
Rat
carboxylic acid metabolic process GO:0019752 289 0.074
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.063
central nervous system development GO:0007417 311 0.062
Rat
rna biosynthetic process GO:0032774 380 0.060
regulation of signal transduction GO:0009966 318 0.060
cellular amino acid metabolic process GO:0006520 107 0.058
negative regulation of metabolic process GO:0009892 331 0.057
regulation of rna biosynthetic process GO:2001141 381 0.057
alpha amino acid metabolic process GO:1901605 71 0.056
monocarboxylic acid metabolic process GO:0032787 152 0.055
regulation of molecular function GO:0065009 398 0.055
tissue development GO:0009888 252 0.055
Rat
single organism catabolic process GO:0044712 283 0.054
nucleic acid templated transcription GO:0097659 379 0.052
programmed cell death GO:0012501 392 0.052
single organism reproductive process GO:0044702 297 0.052
Rat
response to oxygen levels GO:0070482 265 0.051
regulation of nucleic acid templated transcription GO:1903506 380 0.051
heart morphogenesis GO:0003007 3 0.051
catabolic process GO:0009056 351 0.050
amine metabolic process GO:0009308 38 0.048
positive regulation of biosynthetic process GO:0009891 319 0.048
cellular response to oxygen containing compound GO:1901701 386 0.047
Rat
positive regulation of signaling GO:0023056 270 0.047
response to peptide GO:1901652 292 0.046
Rat
response to peptide hormone GO:0043434 278 0.046
Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.046
response to extracellular stimulus GO:0009991 380 0.046
Human Rat
regulation of multicellular organismal development GO:2000026 376 0.046
negative regulation of macromolecule metabolic process GO:0010605 260 0.045
positive regulation of cell proliferation GO:0008284 249 0.044
positive regulation of multicellular organismal process GO:0051240 387 0.044
negative regulation of cellular metabolic process GO:0031324 281 0.044
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.043
cellular amine metabolic process GO:0044106 38 0.043
regulation of apoptotic process GO:0042981 335 0.043
regulation of phosphate metabolic process GO:0019220 349 0.043
response to inorganic substance GO:0010035 377 0.042
Rat
organic acid biosynthetic process GO:0016053 83 0.042
regulation of rna metabolic process GO:0051252 391 0.041
cellular ketone metabolic process GO:0042180 51 0.041
Rat
organic substance catabolic process GO:1901575 316 0.041
negative regulation of gene expression GO:0010629 199 0.040
response to nutrient GO:0007584 248 0.040
Human Rat
regulation of cell proliferation GO:0042127 359 0.039
carboxylic acid biosynthetic process GO:0046394 83 0.039
cardiac ventricle development GO:0003231 1 0.039
organophosphate metabolic process GO:0019637 370 0.038
regulation of nervous system development GO:0051960 264 0.038
regulation of cellular amine metabolic process GO:0033238 8 0.037
cellular response to lipid GO:0071396 201 0.037
Rat
organonitrogen compound biosynthetic process GO:1901566 167 0.037
cellular response to nitrogen compound GO:1901699 210 0.037
Rat
cellular catabolic process GO:0044248 295 0.037
apoptotic process GO:0006915 381 0.036
regulation of neurogenesis GO:0050767 247 0.036
rna metabolic process GO:0016070 406 0.036
negative regulation of rna metabolic process GO:0051253 123 0.035
gland development GO:0048732 155 0.035
Rat
regulation of programmed cell death GO:0043067 341 0.035
multicellular organism reproduction GO:0032504 233 0.035
Rat
positive regulation of phosphorus metabolic process GO:0010562 262 0.035
regulation of transcription dna templated GO:0006355 374 0.035
protein phosphorylation GO:0006468 345 0.034
transcription from rna polymerase ii promoter GO:0006366 252 0.034
cardiac chamber development GO:0003205 1 0.034
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.033
reproductive process GO:0022414 372 0.033
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.033
eye morphogenesis GO:0048592 4 0.033
regulation of cellular amino acid metabolic process GO:0006521 2 0.033
response to nutrient levels GO:0031667 370 0.033
Human Rat
homeostatic process GO:0042592 331 0.033
positive regulation of cell communication GO:0010647 271 0.033
cellular response to peptide GO:1901653 133 0.033
Rat
regulation of cellular protein metabolic process GO:0032268 267 0.032
regulation of cellular ketone metabolic process GO:0010565 27 0.032
small molecule biosynthetic process GO:0044283 124 0.032
Rat
tube development GO:0035295 89 0.031
transcription dna templated GO:0006351 377 0.031
intracellular signal transduction GO:0035556 314 0.031
response to acid chemical GO:0001101 222 0.031
Rat
positive regulation of developmental process GO:0051094 283 0.030
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.030
negative regulation of rna biosynthetic process GO:1902679 118 0.030
response to decreased oxygen levels GO:0036293 237 0.030
regulation of cell development GO:0060284 263 0.029
ribonucleotide metabolic process GO:0009259 231 0.029
response to oxidative stress GO:0006979 186 0.029
Rat
negative regulation of cellular biosynthetic process GO:0031327 161 0.028
regulation of cellular localization GO:0060341 263 0.028
regulation of protein metabolic process GO:0051246 289 0.028
response to hypoxia GO:0001666 231 0.028
cellular response to stress GO:0033554 269 0.028
Rat
positive regulation of cell development GO:0010720 176 0.027
cellular component movement GO:0006928 248 0.027
rhythmic process GO:0048511 156 0.027
positive regulation of response to stimulus GO:0048584 285 0.027
response to ketone GO:1901654 182 0.027
Rat
regulation of phosphorylation GO:0042325 248 0.027
nucleotide metabolic process GO:0009117 279 0.027
neurological system process GO:0050877 219 0.027
negative regulation of programmed cell death GO:0043069 183 0.027
cellular lipid metabolic process GO:0044255 208 0.026
head development GO:0060322 247 0.026
Rat
positive regulation of gene expression GO:0010628 244 0.026
vesicle mediated transport GO:0016192 181 0.026
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.025
anion transport GO:0006820 178 0.025
multi multicellular organism process GO:0044706 138 0.025
Rat
positive regulation of rna biosynthetic process GO:1902680 197 0.025
single organism biosynthetic process GO:0044711 342 0.025
Rat
glomerular mesangial cell proliferation GO:0072110 4 0.025
locomotion GO:0040011 237 0.025
brain development GO:0007420 247 0.025
Rat
nucleobase containing small molecule metabolic process GO:0055086 316 0.025
Rat
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.025
regulation of phosphorus metabolic process GO:0051174 349 0.024
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.024
cellular ion homeostasis GO:0006873 184 0.024
regulation of system process GO:0044057 208 0.024
ion homeostasis GO:0050801 212 0.024
neuron development GO:0048666 286 0.024
bmp signaling pathway GO:0030509 4 0.024
negative regulation of transcription dna templated GO:0045892 116 0.024
cellular response to peptide hormone stimulus GO:0071375 120 0.024
Rat
behavior GO:0007610 205 0.023
Rat
cell projection organization GO:0030030 302 0.023
muscle organ morphogenesis GO:0048644 1 0.023
defense response GO:0006952 194 0.023
Rat
positive regulation of nervous system development GO:0051962 178 0.023
carbohydrate derivative metabolic process GO:1901135 346 0.023
Rat
negative regulation of nucleic acid templated transcription GO:1903507 117 0.023
purine containing compound metabolic process GO:0072521 253 0.022
Rat
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.022
response to external biotic stimulus GO:0043207 221 0.022
Rat
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.022
response to cytokine GO:0034097 215 0.022
Rat
positive regulation of signal transduction GO:0009967 175 0.022
urogenital system development GO:0001655 78 0.022
cell cell signaling GO:0007267 335 0.022
fatty acid metabolic process GO:0006631 99 0.021
negative regulation of cellular protein metabolic process GO:0032269 106 0.021
regulation of neuron differentiation GO:0045664 208 0.021
immune system process GO:0002376 204 0.021
Rat
response to estrogen GO:0043627 232 0.021
Rat
epithelium development GO:0060429 96 0.021
Rat
positive regulation of transcription dna templated GO:0045893 197 0.021
negative regulation of apoptotic process GO:0043066 181 0.021
carbohydrate derivative catabolic process GO:1901136 147 0.021
positive regulation of transport GO:0051050 245 0.021
neuron projection development GO:0031175 273 0.021
organic hydroxy compound metabolic process GO:1901615 115 0.021
renal system development GO:0072001 67 0.021
neuron differentiation GO:0030182 368 0.021
circulatory system development GO:0072359 134 0.021
regulation of catalytic activity GO:0050790 304 0.021
regulation of protein phosphorylation GO:0001932 183 0.021
chemical homeostasis GO:0048878 292 0.020
glycosyl compound metabolic process GO:1901657 182 0.020
Rat
cellular component biogenesis GO:0044085 368 0.020
regulation of cell differentiation GO:0045595 320 0.020
cardiovascular system development GO:0072358 134 0.020
purine nucleotide metabolic process GO:0006163 229 0.020
multi organism reproductive process GO:0044703 262 0.020
Rat
forebrain development GO:0030900 98 0.020
Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.020
glomerular mesangium development GO:0072109 4 0.020
positive regulation of phosphorylation GO:0042327 177 0.020
cellular divalent inorganic cation homeostasis GO:0072503 162 0.020
cardiac muscle tissue morphogenesis GO:0055008 1 0.019
proteolysis GO:0006508 175 0.019
response to glucocorticoid GO:0051384 223 0.019
Rat
cellular cation homeostasis GO:0030003 180 0.019
negative regulation of multicellular organismal process GO:0051241 203 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
cellular chemical homeostasis GO:0055082 247 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
Rat
coenzyme metabolic process GO:0006732 86 0.019
cellular homeostasis GO:0019725 252 0.019
hepaticobiliary system development GO:0061008 90 0.019
regulation of protein modification process GO:0031399 194 0.019
regulation of hormone levels GO:0010817 187 0.019
Rat
divalent inorganic cation homeostasis GO:0072507 165 0.019
cation transmembrane transport GO:0098655 263 0.018
signal transduction by phosphorylation GO:0023014 144 0.018
kidney development GO:0001822 67 0.018
muscle structure development GO:0061061 87 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
reproduction GO:0000003 245 0.018
Rat
response to molecule of bacterial origin GO:0002237 194 0.018
Rat
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
sensory perception GO:0007600 101 0.018
liver development GO:0001889 90 0.018
metal ion homeostasis GO:0055065 186 0.018
gastrulation GO:0007369 2 0.018
response to monosaccharide GO:0034284 159 0.018
Rat
secretion GO:0046903 307 0.018
positive regulation of nucleic acid templated transcription GO:1903508 197 0.018
cation transport GO:0006812 382 0.018
negative regulation of cell death GO:0060548 229 0.018
divalent metal ion transport GO:0070838 132 0.018
cellular modified amino acid metabolic process GO:0006575 61 0.018
negative regulation of protein metabolic process GO:0051248 114 0.018
cellular component morphogenesis GO:0032989 155 0.017
negative regulation of signaling GO:0023057 157 0.017
localization of cell GO:0051674 202 0.017
regeneration GO:0031099 163 0.017
anatomical structure morphogenesis GO:0009653 298 0.017
ribonucleoside metabolic process GO:0009119 174 0.017
Rat
positive regulation of protein modification process GO:0031401 142 0.017
response to bacterium GO:0009617 200 0.017
Rat
positive regulation of cellular component organization GO:0051130 200 0.017
positive regulation of neurogenesis GO:0050769 165 0.017
negative regulation of nervous system development GO:0051961 79 0.017
heart development GO:0007507 72 0.017
positive regulation of cell differentiation GO:0045597 217 0.017
monocarboxylic acid biosynthetic process GO:0072330 48 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.017
cellular response to organic cyclic compound GO:0071407 202 0.017
Rat
response to carbohydrate GO:0009743 183 0.016
Rat
ribonucleotide catabolic process GO:0009261 136 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
peptide hormone secretion GO:0030072 84 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
Rat
aging GO:0007568 241 0.016
organophosphate catabolic process GO:0046434 148 0.016
peptidyl amino acid modification GO:0018193 126 0.016
peptide secretion GO:0002790 86 0.016
regulation of growth GO:0040008 105 0.016
negative regulation of cell proliferation GO:0008285 119 0.016
macromolecular complex subunit organization GO:0043933 339 0.016
transmission of nerve impulse GO:0019226 42 0.016
hormone metabolic process GO:0042445 69 0.016
Rat
limb morphogenesis GO:0035108 4 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
connective tissue development GO:0061448 33 0.015
cofactor metabolic process GO:0051186 95 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
organonitrogen compound catabolic process GO:1901565 179 0.015
development of primary sexual characteristics GO:0045137 107 0.015
Rat
purine ribonucleotide catabolic process GO:0009154 136 0.015
aromatic compound catabolic process GO:0019439 168 0.015
regulation of hormone secretion GO:0046883 106 0.015
calcium ion homeostasis GO:0055074 162 0.015
positive regulation of phosphate metabolic process GO:0045937 262 0.015
response to glucose GO:0009749 136 0.015
negative regulation of molecular function GO:0044092 133 0.015
vascular process in circulatory system GO:0003018 96 0.015
synaptic transmission GO:0007268 235 0.015
cell motility GO:0048870 202 0.015
regulation of cellular component organization GO:0051128 368 0.015
muscle tissue morphogenesis GO:0060415 1 0.015
response to wounding GO:0009611 254 0.014
negative regulation of cell communication GO:0010648 158 0.014
response to amine GO:0014075 46 0.014
icosanoid metabolic process GO:0006690 38 0.014
circulatory system process GO:0003013 183 0.014
Rat
response to reactive oxygen species GO:0000302 120 0.014
Rat
regulation of body fluid levels GO:0050878 90 0.014
oxidation reduction process GO:0055114 304 0.014
positive regulation of transferase activity GO:0051347 81 0.014
signal release GO:0023061 145 0.014
glomerulus vasculature development GO:0072012 6 0.014
sexual reproduction GO:0019953 148 0.014
Rat
regulation of kinase activity GO:0043549 117 0.014
regulation of transferase activity GO:0051338 123 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
response to insulin GO:0032868 133 0.014
Rat
response to biotic stimulus GO:0009607 226 0.014
Rat
response to estradiol GO:0032355 164 0.013
calcium ion transport GO:0006816 131 0.013
inflammatory response GO:0006954 150 0.013
organ regeneration GO:0031100 101 0.013
response to purine containing compound GO:0014074 126 0.013
Rat
response to hexose GO:0009746 144 0.013
nucleoside metabolic process GO:0009116 179 0.013
Rat
gamete generation GO:0007276 124 0.013
cellular component assembly GO:0022607 360 0.013
female pregnancy GO:0007565 122 0.013
Rat
positive regulation of glomerulus development GO:0090193 4 0.013
neuronal action potential GO:0019228 35 0.013
establishment of tissue polarity GO:0007164 2 0.013
muscle organ development GO:0007517 50 0.013
regulation of cell growth GO:0001558 85 0.013
sex differentiation GO:0007548 113 0.013
Rat
hormone transport GO:0009914 121 0.013
regulation of locomotion GO:0040012 148 0.013
organelle organization GO:0006996 266 0.013
leukocyte cell cell adhesion GO:0007159 4 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.013
protein complex subunit organization GO:0071822 302 0.013
cellular response to cytokine stimulus GO:0071345 127 0.013
Rat
organic acid transport GO:0015849 116 0.013
regulation of blood pressure GO:0008217 83 0.013
Rat
regulation of blood vessel size GO:0050880 89 0.013
nucleotide catabolic process GO:0009166 139 0.012
divalent inorganic cation transport GO:0072511 134 0.012
positive regulation of rna metabolic process GO:0051254 203 0.012
embryonic skeletal system development GO:0048706 3 0.012
cellular response to acid chemical GO:0071229 75 0.012
regulation of membrane potential GO:0042391 110 0.012
cell morphogenesis GO:0000902 142 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
regulation of heart contraction GO:0008016 48 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
Rat
hormone secretion GO:0046879 115 0.012
glomerulus development GO:0032835 10 0.012
heart process GO:0003015 57 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
response to growth factor GO:0070848 189 0.012
Rat
regulation of glomerulus development GO:0090192 4 0.012
dendrite development GO:0016358 72 0.012
ras protein signal transduction GO:0007265 29 0.012
mesoderm development GO:0007498 2 0.012
cell growth GO:0016049 104 0.012
male gamete generation GO:0048232 99 0.012
response to lipopolysaccharide GO:0032496 191 0.012
Rat
camera type eye morphogenesis GO:0048593 2 0.012
steroid metabolic process GO:0008202 73 0.012
positive regulation of ion transport GO:0043270 94 0.012
macromolecular complex assembly GO:0065003 273 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
endocytosis GO:0006897 84 0.012
phasic smooth muscle contraction GO:0014821 3 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.012
regulation of peptide transport GO:0090087 87 0.012
renal system vasculature development GO:0061437 6 0.012
negative regulation of signal transduction GO:0009968 83 0.012
regulation of cellular component movement GO:0051270 150 0.012
cellular response to oxidative stress GO:0034599 76 0.012
blood circulation GO:0008015 183 0.012
Rat
cell type specific apoptotic process GO:0097285 134 0.012
gliogenesis GO:0042063 93 0.012
Rat
peptide biosynthetic process GO:0043043 3 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
regulation of immune system process GO:0002682 123 0.012
response to ethanol GO:0045471 162 0.012
axis specification GO:0009798 4 0.011
heterocycle catabolic process GO:0046700 167 0.011
peptide transport GO:0015833 97 0.011
positive regulation of molecular function GO:0044093 230 0.011
positive regulation of immune system process GO:0002684 90 0.011
regulation of peptide hormone secretion GO:0090276 80 0.011
skeletal muscle tissue development GO:0007519 31 0.011
response to corticosteroid GO:0031960 235 0.011
Rat
regulation of ion transport GO:0043269 245 0.011
positive regulation of hormone secretion GO:0046887 65 0.011
response to retinoic acid GO:0032526 63 0.011
growth GO:0040007 165 0.011
regulation of anatomical structure size GO:0090066 135 0.011
positive regulation of glomerular mesangial cell proliferation GO:0072126 4 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
phenol containing compound metabolic process GO:0018958 30 0.011
Rat
regulation of transmembrane transport GO:0034762 122 0.011
maintenance of location GO:0051235 17 0.011
smooth muscle cell proliferation GO:0048659 77 0.011
multicellular organismal signaling GO:0035637 44 0.011
transmembrane transport GO:0055085 412 0.011
multicellular organism growth GO:0035264 1 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
regulation of lipid metabolic process GO:0019216 68 0.011
protein complex biogenesis GO:0070271 263 0.011
intracellular transport GO:0046907 185 0.011
single organism organelle organization GO:1902589 180 0.011
regulation of peptide secretion GO:0002791 82 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
embryonic pattern specification GO:0009880 1 0.011
cellular response to corticosteroid stimulus GO:0071384 69 0.011
cell projection morphogenesis GO:0048858 123 0.011
ribonucleoside monophosphate metabolic process GO:0009161 88 0.011
mapk cascade GO:0000165 140 0.011
purine nucleoside monophosphate metabolic process GO:0009126 84 0.011
sequestering of metal ion GO:0051238 9 0.011
regulation of secretion GO:0051046 224 0.011
regulation of stem cell differentiation GO:2000736 2 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
Rat
heart contraction GO:0060047 57 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
regulation of secretion by cell GO:1903530 208 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
ion transmembrane transport GO:0034220 365 0.010
digestive system development GO:0055123 41 0.010
cation homeostasis GO:0055080 195 0.010
ribonucleotide biosynthetic process GO:0009260 85 0.010
jak stat cascade GO:0007259 26 0.010
ossification GO:0001503 70 0.010
Human
anterior posterior pattern specification GO:0009952 1 0.010
developmental process involved in reproduction GO:0003006 159 0.010
Rat
regulation of tube size GO:0035150 89 0.010
fatty acid derivative metabolic process GO:1901568 38 0.010
amide transport GO:0042886 105 0.010
negative regulation of secretion GO:0051048 82 0.010
carbohydrate metabolic process GO:0005975 130 0.010
regulation of response to stress GO:0080134 126 0.010
purine ribonucleotide metabolic process GO:0009150 227 0.010
cellular response to steroid hormone stimulus GO:0071383 93 0.010
negative regulation of phosphate metabolic process GO:0045936 80 0.010
positive regulation of cell death GO:0010942 184 0.010
sensory perception of pain GO:0019233 73 0.010

Cyp24a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
disease of metabolism DOID:0014667 0 0.020
musculoskeletal system disease DOID:17 0 0.018
muscular disease DOID:0080000 0 0.013
muscle tissue disease DOID:66 0 0.013
sensory system disease DOID:0050155 0 0.013
heart disease DOID:114 0 0.012
cardiovascular system disease DOID:1287 0 0.012
inherited metabolic disorder DOID:655 0 0.012