Rattus norvegicus

27 known processes

Cyp2b2

cytochrome P450, family 2, subfamily b, polypeptide 2

(Aliases: CYPIIB2,Cype)

Cyp2b2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
halogenated hydrocarbon metabolic process GO:0042197 4 0.886
Rat
chlorinated hydrocarbon metabolic process GO:0042196 4 0.851
Rat
naphthalene metabolic process GO:0018931 2 0.744
Rat
epoxygenase p450 pathway GO:0019373 1 0.666
Rat
response to cesium ion GO:0010164 2 0.658
Rat
response to xenobiotic stimulus GO:0009410 23 0.589
Human Rat
arachidonic acid metabolic process GO:0019369 20 0.509
Rat
carboxylic acid metabolic process GO:0019752 289 0.500
Rat
cellular response to xenobiotic stimulus GO:0071466 19 0.478
Human Rat
oxidation reduction process GO:0055114 304 0.457
hepaticobiliary system development GO:0061008 90 0.457
Rat
phenylpropanoid metabolic process GO:0009698 5 0.386
Rat
response to peptide hormone GO:0043434 278 0.376
Rat
cellular response to peptide hormone stimulus GO:0071375 120 0.367
naphthalene containing compound metabolic process GO:0090420 2 0.354
Rat
neutral lipid metabolic process GO:0006638 21 0.338
Rat
fatty acid metabolic process GO:0006631 99 0.331
Rat
response to oxidative stress GO:0006979 186 0.311
Rat
alkaloid metabolic process GO:0009820 3 0.310
organic acid metabolic process GO:0006082 292 0.298
Rat
cellular ketone metabolic process GO:0042180 51 0.277
Human
4 chlorobiphenyl metabolic process GO:0018880 1 0.276
cellular catabolic process GO:0044248 295 0.267
Human
phenylpropanoid catabolic process GO:0046271 3 0.263
lipid metabolic process GO:0006629 283 0.255
Human Rat
single organism catabolic process GO:0044712 283 0.232
unsaturated fatty acid metabolic process GO:0033559 39 0.231
Rat
biphenyl catabolic process GO:0070980 2 0.229
trichloroethylene metabolic process GO:0018979 1 0.208
Rat
multi multicellular organism process GO:0044706 138 0.205
Rat
multi organism reproductive process GO:0044703 262 0.203
Rat
monocarboxylic acid metabolic process GO:0032787 152 0.197
Rat
female pregnancy GO:0007565 122 0.196
Rat
small molecule catabolic process GO:0044282 59 0.191
lipid catabolic process GO:0016042 46 0.190
gland development GO:0048732 155 0.182
Rat
acylglycerol metabolic process GO:0006639 21 0.182
Rat
linoleic acid metabolic process GO:0043651 4 0.179
cellular response to lipid GO:0071396 201 0.166
liver development GO:0001889 90 0.165
Rat
drug catabolic process GO:0042737 1 0.160
Human
response to inorganic substance GO:0010035 377 0.158
cellular response to peptide GO:1901653 133 0.157
catabolic process GO:0009056 351 0.156
Human
coumarin catabolic process GO:0046226 3 0.154
nicotine metabolic process GO:0018933 1 0.152
xenobiotic metabolic process GO:0006805 19 0.146
Human Rat
response to nutrient GO:0007584 248 0.143
oxoacid metabolic process GO:0043436 290 0.141
Rat
long chain fatty acid metabolic process GO:0001676 32 0.127
Rat
response to ketone GO:1901654 182 0.120
Rat
icosanoid metabolic process GO:0006690 38 0.119
Rat
response to acid chemical GO:0001101 222 0.112
Rat
regulation of cellular localization GO:0060341 263 0.111
apoptotic process GO:0006915 381 0.108
response to corticosteroid GO:0031960 235 0.106
response to calcium ion GO:0051592 59 0.105
cellular lipid metabolic process GO:0044255 208 0.101
Rat
exogenous drug catabolic process GO:0042738 1 0.101
Human
fatty acid derivative metabolic process GO:1901568 38 0.098
Rat
secondary metabolic process GO:0019748 15 0.096
Rat
cellular amino acid metabolic process GO:0006520 107 0.096
response to sulfur dioxide GO:0010477 3 0.095
Rat
response to peptide GO:1901652 292 0.093
Rat
response to molecule of bacterial origin GO:0002237 194 0.091
steroid catabolic process GO:0006706 5 0.090
response to ethanol GO:0045471 162 0.090
Rat
cellular response to hormone stimulus GO:0032870 247 0.084
cellular response to ethanol GO:0071361 13 0.083
positive regulation of cellular biosynthetic process GO:0031328 295 0.082
drug metabolic process GO:0017144 11 0.081
response to insulin GO:0032868 133 0.080
Rat
response to lipopolysaccharide GO:0032496 191 0.078
cellular response to corticosteroid stimulus GO:0071384 69 0.078
neurological system process GO:0050877 219 0.075
carboxylic acid catabolic process GO:0046395 49 0.075
steroid metabolic process GO:0008202 73 0.074
Human
coumarin metabolic process GO:0009804 5 0.073
Rat
organonitrogen compound biosynthetic process GO:1901566 167 0.067
Rat
sensory perception GO:0007600 101 0.064
cellular response to nitrogen compound GO:1901699 210 0.064
cellular response to organic cyclic compound GO:0071407 202 0.064
response to glucocorticoid GO:0051384 223 0.061
response to organophosphorus GO:0046683 102 0.060
estrogen catabolic process GO:0006711 1 0.060
cellular response to insulin stimulus GO:0032869 81 0.058
cellular response to organonitrogen compound GO:0071417 197 0.058
cellular response to steroid hormone stimulus GO:0071383 93 0.056
programmed cell death GO:0012501 392 0.054
cellular response to glucocorticoid stimulus GO:0071385 68 0.053
response to nutrient levels GO:0031667 370 0.053
response to extracellular stimulus GO:0009991 380 0.052
organic substance catabolic process GO:1901575 316 0.050
organic hydroxy compound metabolic process GO:1901615 115 0.049
Rat
hormone catabolic process GO:0042447 2 0.047
response to carbohydrate GO:0009743 183 0.047
regulation of cellular ketone metabolic process GO:0010565 27 0.046
response to bacterium GO:0009617 200 0.046
reproductive process GO:0022414 372 0.045
Rat
cellular response to alcohol GO:0097306 87 0.045
aging GO:0007568 241 0.045
pyridine containing compound metabolic process GO:0072524 32 0.044
cellular lipid catabolic process GO:0044242 37 0.044
response to metal ion GO:0010038 253 0.044
ribose phosphate metabolic process GO:0019693 235 0.043
glycerolipid metabolic process GO:0046486 67 0.043
Rat
regulation of cellular amine metabolic process GO:0033238 8 0.042
nucleotide metabolic process GO:0009117 279 0.042
intracellular signal transduction GO:0035556 314 0.042
reproductive system development GO:0061458 128 0.042
regulation of apoptotic process GO:0042981 335 0.041
regulation of cellular amino acid metabolic process GO:0006521 2 0.040
response to external biotic stimulus GO:0043207 221 0.040
cellular response to oxygen containing compound GO:1901701 386 0.038
nitrogen compound transport GO:0071705 229 0.038
cellular response to ketone GO:1901655 51 0.038
blood circulation GO:0008015 183 0.037
response to testosterone GO:0033574 55 0.037
Rat
behavior GO:0007610 205 0.037
reproductive structure development GO:0048608 128 0.037
fatty acid catabolic process GO:0009062 26 0.037
negative regulation of macromolecule metabolic process GO:0010605 260 0.036
g protein coupled receptor signaling pathway GO:0007186 242 0.035
negative regulation of cellular metabolic process GO:0031324 281 0.035
single organism biosynthetic process GO:0044711 342 0.035
neuron neuron synaptic transmission GO:0007270 60 0.035
positive regulation of biosynthetic process GO:0009891 319 0.034
positive regulation of signaling GO:0023056 270 0.034
dopamine metabolic process GO:0042417 12 0.034
Rat
cellular response to testosterone stimulus GO:0071394 5 0.034
cellular amine metabolic process GO:0044106 38 0.034
single organism carbohydrate metabolic process GO:0044723 118 0.034
acute inflammatory response GO:0002526 58 0.033
response to monosaccharide GO:0034284 159 0.033
response to wounding GO:0009611 254 0.033
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.032
anion transport GO:0006820 178 0.032
organic hydroxy compound biosynthetic process GO:1901617 51 0.032
Rat
ras protein signal transduction GO:0007265 29 0.031
organic cyclic compound catabolic process GO:1901361 175 0.031
regulation of protein metabolic process GO:0051246 289 0.031
negative regulation of multicellular organismal process GO:0051241 203 0.031
heterocycle catabolic process GO:0046700 167 0.031
response to reactive oxygen species GO:0000302 120 0.031
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.031
inflammatory response GO:0006954 150 0.031
nucleoside phosphate metabolic process GO:0006753 283 0.031
cellular response to stress GO:0033554 269 0.030
amine metabolic process GO:0009308 38 0.030
response to fatty acid GO:0070542 65 0.030
negative regulation of metabolic process GO:0009892 331 0.030
single organism reproductive process GO:0044702 297 0.030
terpenoid metabolic process GO:0006721 37 0.030
Rat
transmembrane transport GO:0055085 412 0.030
positive regulation of cell motility GO:2000147 97 0.029
phenol containing compound metabolic process GO:0018958 30 0.029
Rat
organ regeneration GO:0031100 101 0.029
regulation of intracellular signal transduction GO:1902531 218 0.029
regulation of hormone levels GO:0010817 187 0.029
regulation of cellular protein metabolic process GO:0032268 267 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.028
catechol containing compound biosynthetic process GO:0009713 9 0.028
Rat
catecholamine biosynthetic process GO:0042423 9 0.028
Rat
lipid oxidation GO:0034440 30 0.027
triglyceride metabolic process GO:0006641 21 0.027
Rat
regulation of system process GO:0044057 208 0.027
cellular response to oxidative stress GO:0034599 76 0.027
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.026
regulation of signal transduction GO:0009966 318 0.026
aromatic compound catabolic process GO:0019439 168 0.025
response to camp GO:0051591 91 0.025
metal ion homeostasis GO:0055065 186 0.025
negative regulation of apoptotic process GO:0043066 181 0.025
sensory perception of pain GO:0019233 73 0.025
organophosphate metabolic process GO:0019637 370 0.025
regulation of molecular function GO:0065009 398 0.025
secretion GO:0046903 307 0.025
purine nucleoside catabolic process GO:0006152 124 0.024
positive regulation of intracellular signal transduction GO:1902533 138 0.024
purine ribonucleotide metabolic process GO:0009150 227 0.024
negative regulation of cell proliferation GO:0008285 119 0.024
positive regulation of cellular amine metabolic process GO:0033240 3 0.024
response to estradiol GO:0032355 164 0.024
regulation of phosphate metabolic process GO:0019220 349 0.024
divalent inorganic cation transport GO:0072511 134 0.023
regulation of secretion by cell GO:1903530 208 0.023
anterior posterior pattern specification GO:0009952 1 0.023
xenobiotic catabolic process GO:0042178 7 0.023
defense response GO:0006952 194 0.023
regulation of behavior GO:0050795 61 0.022
muscle system process GO:0003012 115 0.022
response to oxygen levels GO:0070482 265 0.022
positive regulation of phosphorus metabolic process GO:0010562 262 0.022
benzene containing compound metabolic process GO:0042537 22 0.022
lipid storage GO:0019915 1 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.022
purine nucleotide metabolic process GO:0006163 229 0.022
catechol containing compound metabolic process GO:0009712 19 0.021
Rat
biphenyl metabolic process GO:0018879 10 0.021
regulation of programmed cell death GO:0043067 341 0.021
positive regulation of signal transduction GO:0009967 175 0.021
positive regulation of transport GO:0051050 245 0.021
carbohydrate derivative metabolic process GO:1901135 346 0.021
regulation of hormone secretion GO:0046883 106 0.021
single organism cellular localization GO:1902580 102 0.021
regeneration GO:0031099 163 0.021
organic acid transport GO:0015849 116 0.021
ion homeostasis GO:0050801 212 0.021
transcription dna templated GO:0006351 377 0.021
acute phase response GO:0006953 20 0.021
positive regulation of nucleotide metabolic process GO:0045981 91 0.020
response to cytokine GO:0034097 215 0.020
carbohydrate metabolic process GO:0005975 130 0.020
multicellular organism reproduction GO:0032504 233 0.020
regulation of secretion GO:0051046 224 0.020
response to hypoxia GO:0001666 231 0.020
response to decreased oxygen levels GO:0036293 237 0.020
cyclic nucleotide biosynthetic process GO:0009190 63 0.019
regulation of mapk cascade GO:0043408 116 0.019
circulatory system process GO:0003013 183 0.019
negative regulation of programmed cell death GO:0043069 183 0.019
cellular response to endogenous stimulus GO:0071495 377 0.019
response to transition metal nanoparticle GO:1990267 122 0.019
response to biotic stimulus GO:0009607 226 0.019
response to growth factor GO:0070848 189 0.019
response to ionizing radiation GO:0010212 59 0.019
Rat
positive regulation of cell communication GO:0010647 271 0.019
secretion by cell GO:0032940 248 0.019
organic acid catabolic process GO:0016054 49 0.019
cellular response to external stimulus GO:0071496 118 0.019
ion transmembrane transport GO:0034220 365 0.019
regulation of hydrolase activity GO:0051336 143 0.019
response to alkaloid GO:0043279 132 0.018
ribonucleotide biosynthetic process GO:0009260 85 0.018
negative regulation of protein metabolic process GO:0051248 114 0.018
small molecule biosynthetic process GO:0044283 124 0.018
head development GO:0060322 247 0.018
calcium ion transport GO:0006816 131 0.018
positive regulation of cellular protein metabolic process GO:0032270 167 0.018
isoprenoid metabolic process GO:0006720 45 0.018
Rat
nucleobase containing small molecule metabolic process GO:0055086 316 0.018
positive regulation of protein metabolic process GO:0051247 178 0.018
response to purine containing compound GO:0014074 126 0.018
divalent metal ion transport GO:0070838 132 0.018
anatomical structure morphogenesis GO:0009653 298 0.018
response to vitamin GO:0033273 131 0.018
glycosyl compound metabolic process GO:1901657 182 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.017
regulation of protein modification process GO:0031399 194 0.017
response to hexose GO:0009746 144 0.017
response to hydrogen peroxide GO:0042542 89 0.017
ribonucleotide metabolic process GO:0009259 231 0.017
vascular process in circulatory system GO:0003018 96 0.017
monocarboxylic acid catabolic process GO:0072329 28 0.017
carboxylic acid biosynthetic process GO:0046394 83 0.017
chemical homeostasis GO:0048878 292 0.017
regulation of phosphorylation GO:0042325 248 0.016
response to estrogen GO:0043627 232 0.016
response to radiation GO:0009314 137 0.016
Rat
small gtpase mediated signal transduction GO:0007264 36 0.016
positive regulation of phosphate metabolic process GO:0045937 262 0.016
insecticide metabolic process GO:0017143 4 0.016
hexose metabolic process GO:0019318 58 0.016
regulation of anatomical structure size GO:0090066 135 0.016
negative regulation of cell death GO:0060548 229 0.016
carboxylic acid transport GO:0046942 115 0.016
negative regulation of response to stimulus GO:0048585 155 0.016
positive regulation of response to stimulus GO:0048584 285 0.016
response to mechanical stimulus GO:0009612 134 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.016
cellular response to cytokine stimulus GO:0071345 127 0.015
regulation of peptide transport GO:0090087 87 0.015
regulation of protein phosphorylation GO:0001932 183 0.015
purine ribonucleotide biosynthetic process GO:0009152 81 0.015
cellular divalent inorganic cation homeostasis GO:0072503 162 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
response to amino acid GO:0043200 75 0.015
dna metabolic process GO:0006259 96 0.015
sexual reproduction GO:0019953 148 0.015
establishment of protein localization GO:0045184 141 0.015
regulation of multicellular organismal development GO:2000026 376 0.015
regulation of neuron projection development GO:0010975 161 0.015
proteolysis GO:0006508 175 0.015
ribonucleoside catabolic process GO:0042454 126 0.014
vasoconstriction GO:0042310 54 0.014
regulation of peptide hormone secretion GO:0090276 80 0.014
positive regulation of locomotion GO:0040017 102 0.014
amide transport GO:0042886 105 0.014
regulation of membrane potential GO:0042391 110 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
homeostatic process GO:0042592 331 0.014
heart morphogenesis GO:0003007 3 0.014
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 34 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
amino acid transport GO:0006865 70 0.014
cyclic nucleotide metabolic process GO:0009187 80 0.014
neuron differentiation GO:0030182 368 0.014
leukocyte differentiation GO:0002521 30 0.013
gamete generation GO:0007276 124 0.013
positive regulation of multicellular organismal process GO:0051240 387 0.013
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.013
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.013
fatty acid oxidation GO:0019395 29 0.013
metal ion transport GO:0030001 289 0.013
axis specification GO:0009798 4 0.013
maintenance of location GO:0051235 17 0.013
tissue development GO:0009888 252 0.013
hormone transport GO:0009914 121 0.013
regulation of body fluid levels GO:0050878 90 0.013
nucleoside triphosphate metabolic process GO:0009141 144 0.013
developmental process involved in reproduction GO:0003006 159 0.013
neuron projection development GO:0031175 273 0.013
negative regulation of transport GO:0051051 136 0.013
regulation of lipid biosynthetic process GO:0046890 38 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
macromolecule localization GO:0033036 252 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.013
cellular hormone metabolic process GO:0034754 49 0.013
regulation of peptide secretion GO:0002791 82 0.013
positive regulation of molecular function GO:0044093 230 0.013
purine containing compound metabolic process GO:0072521 253 0.013
single organism intracellular transport GO:1902582 166 0.013
embryonic pattern specification GO:0009880 1 0.013
cellular homeostasis GO:0019725 252 0.012
retinoid metabolic process GO:0001523 24 0.012
Rat
regulation of cell differentiation GO:0045595 320 0.012
negative regulation of secretion GO:0051048 82 0.012
positive regulation of cell death GO:0010942 184 0.012
response to glucose GO:0009749 136 0.012
diterpenoid metabolic process GO:0016101 33 0.012
Rat
peptidyl tyrosine modification GO:0018212 72 0.012
cellular ion homeostasis GO:0006873 184 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
c21 steroid hormone metabolic process GO:0008207 14 0.012
cellular response to growth hormone stimulus GO:0071378 6 0.012
ribonucleoside monophosphate metabolic process GO:0009161 88 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
lipid localization GO:0010876 62 0.012
response to vitamin d GO:0033280 34 0.012
cyclic purine nucleotide metabolic process GO:0052652 62 0.012
protein complex assembly GO:0006461 263 0.012
monosaccharide metabolic process GO:0005996 61 0.012
neuromuscular synaptic transmission GO:0007274 2 0.012
cellular response to metal ion GO:0071248 55 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
intracellular transport GO:0046907 185 0.012
cation transport GO:0006812 382 0.012
sex differentiation GO:0007548 113 0.012
purine containing compound biosynthetic process GO:0072522 85 0.012
vesicle mediated transport GO:0016192 181 0.012
sensory perception of light stimulus GO:0050953 3 0.012
cytokine biosynthetic process GO:0042089 3 0.012
positive regulation of mapk cascade GO:0043410 92 0.012
single organism membrane organization GO:0044802 74 0.012
regulation of nucleotide biosynthetic process GO:0030808 47 0.011
regulation of response to stress GO:0080134 126 0.011
regulation of catalytic activity GO:0050790 304 0.011
cellular response to reactive oxygen species GO:0034614 55 0.011
cellular response to acid chemical GO:0071229 75 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.011
cell activation GO:0001775 97 0.011
growth GO:0040007 165 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
development of primary sexual characteristics GO:0045137 107 0.011
male gonad development GO:0008584 59 0.011
organic anion transport GO:0015711 132 0.011
single organism behavior GO:0044708 130 0.011
eosinophil migration GO:0072677 3 0.011
regulation of rna biosynthetic process GO:2001141 381 0.011
regulation of cellular component organization GO:0051128 368 0.011
negative regulation of molecular function GO:0044092 133 0.011
alpha amino acid biosynthetic process GO:1901607 23 0.011
regulation of muscle system process GO:0090257 79 0.011
cell cell signaling GO:0007267 335 0.011
detection of stimulus GO:0051606 24 0.011
reproduction GO:0000003 245 0.011
c21 steroid hormone biosynthetic process GO:0006700 10 0.011
positive regulation of cell development GO:0010720 176 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
cofactor metabolic process GO:0051186 95 0.011
regulation of rna metabolic process GO:0051252 391 0.011
vasculature development GO:0001944 70 0.011
neuronal action potential GO:0019228 35 0.011
nucleotide catabolic process GO:0009166 139 0.011
response to dexamethasone GO:0071548 49 0.010
vitamin biosynthetic process GO:0009110 3 0.010
muscle structure development GO:0061061 87 0.010
reactive oxygen species metabolic process GO:0072593 37 0.010
response to activity GO:0014823 73 0.010
membrane organization GO:0061024 94 0.010
protein processing GO:0016485 68 0.010
negative regulation of gene expression GO:0010629 199 0.010
regulation of homeostatic process GO:0032844 101 0.010
monocarboxylic acid biosynthetic process GO:0072330 48 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.010
regulation of cytokine biosynthetic process GO:0042035 3 0.010
carbohydrate derivative biosynthetic process GO:1901137 124 0.010
male gamete generation GO:0048232 99 0.010
male sex differentiation GO:0046661 64 0.010
gonad development GO:0008406 104 0.010
spermatogenesis GO:0007283 99 0.010
visual perception GO:0007601 3 0.010
fertilization GO:0009566 3 0.010
enzyme linked receptor protein signaling pathway GO:0007167 116 0.010

Cyp2b2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
cardiovascular system disease DOID:1287 0 0.018
disease of metabolism DOID:0014667 0 0.017
inherited metabolic disorder DOID:655 0 0.017