Rattus norvegicus

175 known processes

Daxx

death-domain associated protein

(Aliases: MGC156601)

Daxx biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna metabolic process GO:0016070 406 0.150
regulation of rna metabolic process GO:0051252 391 0.136
regulation of transcription dna templated GO:0006355 374 0.125
positive regulation of molecular function GO:0044093 230 0.115
Human
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.111
nucleic acid templated transcription GO:0097659 379 0.110
regulation of nucleic acid templated transcription GO:1903506 380 0.101
transcription from rna polymerase ii promoter GO:0006366 252 0.094
macromolecular complex subunit organization GO:0043933 339 0.086
regulation of phosphate metabolic process GO:0019220 349 0.085
transcription dna templated GO:0006351 377 0.078
rna biosynthetic process GO:0032774 380 0.073
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.069
organelle organization GO:0006996 266 0.068
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.066
positive regulation of phosphate metabolic process GO:0045937 262 0.065
negative regulation of biosynthetic process GO:0009890 168 0.064
negative regulation of macromolecule metabolic process GO:0010605 260 0.062
negative regulation of nucleic acid templated transcription GO:1903507 117 0.060
negative regulation of metabolic process GO:0009892 331 0.057
positive regulation of rna metabolic process GO:0051254 203 0.056
negative regulation of cellular biosynthetic process GO:0031327 161 0.056
positive regulation of signaling GO:0023056 270 0.052
negative regulation of rna biosynthetic process GO:1902679 118 0.051
positive regulation of rna biosynthetic process GO:1902680 197 0.051
positive regulation of cellular protein metabolic process GO:0032270 167 0.051
regulation of cellular component organization GO:0051128 368 0.051
positive regulation of gene expression GO:0010628 244 0.051
positive regulation of biosynthetic process GO:0009891 319 0.050
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.050
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.049
protein complex subunit organization GO:0071822 302 0.047
Human
programmed cell death GO:0012501 392 0.047
regulation of rna biosynthetic process GO:2001141 381 0.046
chromatin assembly or disassembly GO:0006333 1 0.046
Human
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.045
apoptotic process GO:0006915 381 0.045
positive regulation of cellular biosynthetic process GO:0031328 295 0.044
regulation of programmed cell death GO:0043067 341 0.044
positive regulation of transcription dna templated GO:0045893 197 0.044
protein complex biogenesis GO:0070271 263 0.044
Human
intracellular signal transduction GO:0035556 314 0.043
regulation of apoptotic process GO:0042981 335 0.043
positive regulation of nucleic acid templated transcription GO:1903508 197 0.043
regulation of protein modification process GO:0031399 194 0.042
single organism organelle organization GO:1902589 180 0.041
regulation of phosphorus metabolic process GO:0051174 349 0.041
nucleobase containing small molecule metabolic process GO:0055086 316 0.041
positive regulation of phosphorus metabolic process GO:0010562 262 0.040
positive regulation of programmed cell death GO:0043068 157 0.040
response to decreased oxygen levels GO:0036293 237 0.040
positive regulation of cell death GO:0010942 184 0.040
macromolecular complex assembly GO:0065003 273 0.038
Human
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.037
regulation of molecular function GO:0065009 398 0.036
Human
cellular component assembly GO:0022607 360 0.035
Human
cell cycle checkpoint GO:0000075 2 0.034
small gtpase mediated signal transduction GO:0007264 36 0.034
cellular response to stress GO:0033554 269 0.034
regulation of intracellular signal transduction GO:1902531 218 0.034
cellular response to oxygen containing compound GO:1901701 386 0.034
regulation of cell differentiation GO:0045595 320 0.033
regulation of catalytic activity GO:0050790 304 0.033
Human
response to hypoxia GO:0001666 231 0.033
reproductive process GO:0022414 372 0.032
ras protein signal transduction GO:0007265 29 0.032
neuron differentiation GO:0030182 368 0.032
positive regulation of protein metabolic process GO:0051247 178 0.032
regulation of cell development GO:0060284 263 0.031
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.031
positive regulation of developmental process GO:0051094 283 0.031
positive regulation of response to stimulus GO:0048584 285 0.031
regulation of phosphorylation GO:0042325 248 0.030
positive regulation of cell communication GO:0010647 271 0.030
chromosome organization GO:0051276 36 0.030
nucleoside phosphate metabolic process GO:0006753 283 0.030
ribose phosphate metabolic process GO:0019693 235 0.029
cellular component biogenesis GO:0044085 368 0.029
Human
ribonucleotide metabolic process GO:0009259 231 0.029
response to radiation GO:0009314 137 0.029
purine ribonucleotide metabolic process GO:0009150 227 0.029
organonitrogen compound catabolic process GO:1901565 179 0.029
positive regulation of multicellular organismal process GO:0051240 387 0.029
cellular macromolecule localization GO:0070727 122 0.028
regulation of purine nucleotide metabolic process GO:1900542 115 0.028
negative regulation of cellular metabolic process GO:0031324 281 0.028
positive regulation of catalytic activity GO:0043085 184 0.028
Human
positive regulation of nucleotide metabolic process GO:0045981 91 0.028
regulation of signal transduction GO:0009966 318 0.028
multi organism reproductive process GO:0044703 262 0.028
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.027
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.027
purine containing compound metabolic process GO:0072521 253 0.026
urogenital system development GO:0001655 78 0.026
protein oligomerization GO:0051259 191 0.026
homeostatic process GO:0042592 331 0.026
negative regulation of transcription dna templated GO:0045892 116 0.026
anatomical structure morphogenesis GO:0009653 298 0.026
dna integrity checkpoint GO:0031570 2 0.026
dna metabolic process GO:0006259 96 0.026
Human
regulation of cellular protein metabolic process GO:0032268 267 0.026
oxoacid metabolic process GO:0043436 290 0.025
negative regulation of cell cycle phase transition GO:1901988 4 0.025
regulation of cell proliferation GO:0042127 359 0.025
response to extracellular stimulus GO:0009991 380 0.025
response to nutrient levels GO:0031667 370 0.025
positive regulation of hydrolase activity GO:0051345 86 0.025
multicellular organismal reproductive process GO:0048609 233 0.025
regulation of multicellular organismal development GO:2000026 376 0.025
response to oxygen levels GO:0070482 265 0.024
chromatin organization GO:0006325 34 0.024
catabolic process GO:0009056 351 0.024
nucleotide metabolic process GO:0009117 279 0.024
reproduction GO:0000003 245 0.023
positive regulation of mitochondrion organization GO:0010822 4 0.023
macromolecule localization GO:0033036 252 0.023
positive regulation of cellular component organization GO:0051130 200 0.023
neuron projection development GO:0031175 273 0.023
cellular chemical homeostasis GO:0055082 247 0.023
locomotion GO:0040011 237 0.022
positive regulation of nervous system development GO:0051962 178 0.022
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.022
positive regulation of apoptotic process GO:0043065 154 0.022
single organism reproductive process GO:0044702 297 0.022
central nervous system development GO:0007417 311 0.022
sexual reproduction GO:0019953 148 0.022
purine nucleotide metabolic process GO:0006163 229 0.021
negative regulation of rna metabolic process GO:0051253 123 0.021
cellular response to endogenous stimulus GO:0071495 377 0.021
response to oxidative stress GO:0006979 186 0.021
cell migration GO:0016477 197 0.021
ribonucleoside triphosphate catabolic process GO:0009203 122 0.021
carbohydrate derivative metabolic process GO:1901135 346 0.020
positive regulation of signal transduction GO:0009967 175 0.020
regulation of system process GO:0044057 208 0.020
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.020
nucleoside metabolic process GO:0009116 179 0.020
protein phosphorylation GO:0006468 345 0.020
purine nucleoside triphosphate metabolic process GO:0009144 141 0.020
cellular amine metabolic process GO:0044106 38 0.020
positive regulation of intracellular signal transduction GO:1902533 138 0.020
cellular protein localization GO:0034613 122 0.020
regulation of protein phosphorylation GO:0001932 183 0.020
mapk cascade GO:0000165 140 0.020
regulation of nucleotide metabolic process GO:0006140 117 0.020
response to cytokine GO:0034097 215 0.019
negative regulation of cell proliferation GO:0008285 119 0.019
negative regulation of cell death GO:0060548 229 0.019
ribonucleoside catabolic process GO:0042454 126 0.019
cell projection organization GO:0030030 302 0.019
glycosyl compound metabolic process GO:1901657 182 0.019
nucleoside triphosphate metabolic process GO:0009141 144 0.019
regulation of transferase activity GO:0051338 123 0.019
Human
ribonucleoside metabolic process GO:0009119 174 0.019
regulation of protein kinase activity GO:0045859 105 0.019
Human
kidney development GO:0001822 67 0.019
growth GO:0040007 165 0.019
negative regulation of gene expression GO:0010629 199 0.018
purine ribonucleotide catabolic process GO:0009154 136 0.018
negative regulation of programmed cell death GO:0043069 183 0.018
response to acid chemical GO:0001101 222 0.018
regulation of protein metabolic process GO:0051246 289 0.018
regulation of cellular amino acid metabolic process GO:0006521 2 0.018
transmembrane transport GO:0055085 412 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.018
regulation of nervous system development GO:0051960 264 0.018
positive regulation of transferase activity GO:0051347 81 0.017
Human
cellular component movement GO:0006928 248 0.017
chemical homeostasis GO:0048878 292 0.017
organic substance catabolic process GO:1901575 316 0.017
purine nucleoside catabolic process GO:0006152 124 0.017
cellular response to oxidative stress GO:0034599 76 0.017
positive regulation of cell differentiation GO:0045597 217 0.017
multicellular organism reproduction GO:0032504 233 0.017
cell type specific apoptotic process GO:0097285 134 0.017
response to inorganic substance GO:0010035 377 0.017
regulation of growth GO:0040008 105 0.017
cell morphogenesis GO:0000902 142 0.017
mitotic spindle organization GO:0007052 2 0.017
positive regulation of neurogenesis GO:0050769 165 0.017
cellular cation homeostasis GO:0030003 180 0.017
g protein coupled receptor signaling pathway GO:0007186 242 0.017
nucleoside catabolic process GO:0009164 126 0.016
cellular ketone metabolic process GO:0042180 51 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
response to starvation GO:0042594 59 0.016
signal transduction by phosphorylation GO:0023014 144 0.016
ribonucleoside triphosphate metabolic process GO:0009199 141 0.016
cellular homeostasis GO:0019725 252 0.016
purine ribonucleoside catabolic process GO:0046130 124 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.016
amine metabolic process GO:0009308 38 0.016
intracellular transport GO:0046907 185 0.016
cellular response to cytokine stimulus GO:0071345 127 0.016
brain development GO:0007420 247 0.016
protein localization GO:0008104 191 0.016
cell cell signaling GO:0007267 335 0.016
positive regulation of kinase activity GO:0033674 77 0.016
Human
neuron development GO:0048666 286 0.015
response to biotic stimulus GO:0009607 226 0.015
regulation of cell migration GO:0030334 128 0.015
heterocycle catabolic process GO:0046700 167 0.015
positive regulation of protein modification process GO:0031401 142 0.015
response to ionizing radiation GO:0010212 59 0.015
aging GO:0007568 241 0.015
aromatic compound catabolic process GO:0019439 168 0.015
regulation of mapk cascade GO:0043408 116 0.015
purine nucleoside triphosphate catabolic process GO:0009146 122 0.015
cellular response to organic cyclic compound GO:0071407 202 0.015
positive regulation of mapk cascade GO:0043410 92 0.015
histone h3 acetylation GO:0043966 2 0.015
single organism catabolic process GO:0044712 283 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
cation homeostasis GO:0055080 195 0.015
regulation of neurogenesis GO:0050767 247 0.015
positive regulation of cell proliferation GO:0008284 249 0.015
proteolysis GO:0006508 175 0.014
regulation of neuron differentiation GO:0045664 208 0.014
mitotic cell cycle checkpoint GO:0007093 1 0.014
cellular response to oxygen levels GO:0071453 60 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
carboxylic acid metabolic process GO:0019752 289 0.014
spermatogenesis GO:0007283 99 0.014
regulation of cellular component movement GO:0051270 150 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
cation transport GO:0006812 382 0.014
ribonucleotide catabolic process GO:0009261 136 0.014
regulation of cell cycle arrest GO:0071156 2 0.014
cellular amino acid metabolic process GO:0006520 107 0.014
gamete generation GO:0007276 124 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
gastrulation GO:0007369 2 0.014
regulation of mrna splicing via spliceosome GO:0048024 3 0.014
metal ion transport GO:0030001 289 0.013
glycosyl compound catabolic process GO:1901658 126 0.013
synaptic transmission GO:0007268 235 0.013
cellular ion homeostasis GO:0006873 184 0.013
regulation of purine nucleotide catabolic process GO:0033121 65 0.013
protein complex assembly GO:0006461 263 0.013
Human
response to other organism GO:0051707 220 0.013
regulation of catabolic process GO:0009894 113 0.013
purine nucleotide catabolic process GO:0006195 136 0.013
cell motility GO:0048870 202 0.013
organic anion transport GO:0015711 132 0.013
positive regulation of transport GO:0051050 245 0.013
cellular response to hormone stimulus GO:0032870 247 0.013
organophosphate metabolic process GO:0019637 370 0.013
axis specification GO:0009798 4 0.013
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 1 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
anion transport GO:0006820 178 0.012
regulation of nucleotide catabolic process GO:0030811 65 0.012
positive regulation of cellular component biogenesis GO:0044089 55 0.012
spindle organization GO:0007051 2 0.012
ion transmembrane transport GO:0034220 365 0.012
male gamete generation GO:0048232 99 0.012
single organism intracellular transport GO:1902582 166 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
response to monosaccharide GO:0034284 159 0.012
regulation of hydrolase activity GO:0051336 143 0.012
multicellular organism growth GO:0035264 1 0.012
gliogenesis GO:0042063 93 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.012
negative regulation of developmental process GO:0051093 125 0.011
response to estradiol GO:0032355 164 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
regulation of organelle organization GO:0033043 80 0.011
response to peptide hormone GO:0043434 278 0.011
organic acid metabolic process GO:0006082 292 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
cellular response to lipid GO:0071396 201 0.011
positive regulation of gtpase activity GO:0043547 47 0.011
positive regulation of nucleoside metabolic process GO:0045979 55 0.011
activation of protein kinase activity GO:0032147 47 0.011
response to carbohydrate GO:0009743 183 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
positive regulation of catabolic process GO:0009896 78 0.011
cell growth GO:0016049 104 0.011
cellular response to hypoxia GO:0071456 51 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
negative regulation of neurogenesis GO:0050768 78 0.011
positive regulation of cell development GO:0010720 176 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
response to purine containing compound GO:0014074 126 0.011
response to light stimulus GO:0009416 52 0.011
circadian regulation of gene expression GO:0032922 3 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
renal system development GO:0072001 67 0.011
single organism biosynthetic process GO:0044711 342 0.011
negative regulation of molecular function GO:0044092 133 0.011
positive regulation of nucleotide catabolic process GO:0030813 53 0.010
nucleosome organization GO:0034728 1 0.010
Human
regulation of ion transport GO:0043269 245 0.010
purine containing compound biosynthetic process GO:0072522 85 0.010
regulation of cell projection organization GO:0031344 175 0.010
organic acid transport GO:0015849 116 0.010
purine containing compound catabolic process GO:0072523 138 0.010
cellular response to nutrient levels GO:0031669 60 0.010
cytoskeleton organization GO:0007010 111 0.010
muscle system process GO:0003012 115 0.010
embryonic pattern specification GO:0009880 1 0.010

Daxx disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.041
nervous system disease DOID:863 0 0.029
disease of anatomical entity DOID:7 0 0.029
sensory system disease DOID:0050155 0 0.026
cancer DOID:162 0 0.024
eye and adnexa disease DOID:1492 0 0.019
eye disease DOID:5614 0 0.019
liver cancer DOID:3571 0 0.017
organ system cancer DOID:0050686 0 0.017
gastrointestinal system cancer DOID:3119 0 0.017
retinal disease DOID:5679 0 0.014
central nervous system disease DOID:331 0 0.014
colorectal cancer DOID:9256 0 0.013
large intestine cancer DOID:5672 0 0.013
intestinal cancer DOID:10155 0 0.013
colon cancer DOID:219 0 0.013
benign neoplasm DOID:0060072 0 0.013
colon carcinoma DOID:1520 0 0.012
hepatocellular carcinoma DOID:684 0 0.012
liver carcinoma DOID:686 0 0.012