Rattus norvegicus

22 known processes

Dctn2

dynactin 2

(Aliases: MGC93976)

Dctn2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular component organization GO:0051128 368 0.112
cellular response to stress GO:0033554 269 0.093
protein localization GO:0008104 191 0.092
neuron development GO:0048666 286 0.088
cellular component movement GO:0006928 248 0.087
neuron projection development GO:0031175 273 0.078
cell cycle GO:0007049 101 0.077
regulation of rna metabolic process GO:0051252 391 0.075
positive regulation of cell projection organization GO:0031346 111 0.072
positive regulation of multicellular organismal process GO:0051240 387 0.069
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.069
macromolecular complex assembly GO:0065003 273 0.069
organelle organization GO:0006996 266 0.065
positive regulation of nervous system development GO:0051962 178 0.064
positive regulation of cell communication GO:0010647 271 0.063
response to oxidative stress GO:0006979 186 0.063
negative regulation of macromolecule metabolic process GO:0010605 260 0.060
protein phosphorylation GO:0006468 345 0.059
programmed cell death GO:0012501 392 0.059
intracellular signal transduction GO:0035556 314 0.058
catabolic process GO:0009056 351 0.058
neuron differentiation GO:0030182 368 0.058
nucleic acid templated transcription GO:0097659 379 0.057
cellular response to endogenous stimulus GO:0071495 377 0.057
cell morphogenesis GO:0000902 142 0.056
response to hypoxia GO:0001666 231 0.056
organonitrogen compound catabolic process GO:1901565 179 0.055
cell part morphogenesis GO:0032990 123 0.055
dendrite morphogenesis GO:0048813 43 0.053
positive regulation of developmental process GO:0051094 283 0.052
carbohydrate derivative metabolic process GO:1901135 346 0.051
positive regulation of cell differentiation GO:0045597 217 0.051
regulation of catabolic process GO:0009894 113 0.051
anatomical structure morphogenesis GO:0009653 298 0.050
cation transport GO:0006812 382 0.048
cellular catabolic process GO:0044248 295 0.047
regulation of phosphorylation GO:0042325 248 0.047
positive regulation of cell development GO:0010720 176 0.047
regulation of transcription dna templated GO:0006355 374 0.044
regulation of phosphorus metabolic process GO:0051174 349 0.044
regulation of phosphate metabolic process GO:0019220 349 0.044
positive regulation of rna metabolic process GO:0051254 203 0.043
positive regulation of response to stimulus GO:0048584 285 0.043
positive regulation of phosphate metabolic process GO:0045937 262 0.043
cellular protein localization GO:0034613 122 0.043
positive regulation of neuron differentiation GO:0045666 126 0.042
positive regulation of molecular function GO:0044093 230 0.042
locomotion GO:0040011 237 0.042
response to nutrient levels GO:0031667 370 0.042
chemotaxis GO:0006935 66 0.041
cell cycle process GO:0022402 57 0.041
organic substance catabolic process GO:1901575 316 0.041
transcription dna templated GO:0006351 377 0.041
regulation of molecular function GO:0065009 398 0.041
regulation of cellular catabolic process GO:0031329 101 0.041
purine nucleoside catabolic process GO:0006152 124 0.039
regulation of neuron death GO:1901214 115 0.039
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.039
regulation of hydrolase activity GO:0051336 143 0.039
regulation of purine nucleotide catabolic process GO:0033121 65 0.039
negative regulation of cell death GO:0060548 229 0.039
regulation of neurogenesis GO:0050767 247 0.037
reproduction GO:0000003 245 0.037
response to oxygen levels GO:0070482 265 0.036
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.036
oxoacid metabolic process GO:0043436 290 0.036
regulation of neuron projection development GO:0010975 161 0.035
regulation of cellular amino acid metabolic process GO:0006521 2 0.035
positive regulation of cellular component organization GO:0051130 200 0.035
positive regulation of nucleic acid templated transcription GO:1903508 197 0.035
dna metabolic process GO:0006259 96 0.035
response to inorganic substance GO:0010035 377 0.035
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.034
rna biosynthetic process GO:0032774 380 0.034
regulation of protein modification process GO:0031399 194 0.034
regulation of nucleic acid templated transcription GO:1903506 380 0.034
response to extracellular stimulus GO:0009991 380 0.033
positive regulation of gene expression GO:0010628 244 0.033
neuron death GO:0070997 127 0.033
cellular amine metabolic process GO:0044106 38 0.033
cell migration GO:0016477 197 0.033
positive regulation of rna biosynthetic process GO:1902680 197 0.032
eye morphogenesis GO:0048592 4 0.032
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.032
neuron projection morphogenesis GO:0048812 122 0.032
positive regulation of transcription dna templated GO:0045893 197 0.032
localization of cell GO:0051674 202 0.032
positive regulation of signaling GO:0023056 270 0.032
response to estradiol GO:0032355 164 0.031
protein transport GO:0015031 132 0.031
guanosine containing compound catabolic process GO:1901069 71 0.031
cell morphogenesis involved in differentiation GO:0000904 119 0.031
response to corticosteroid GO:0031960 235 0.031
regulation of signal transduction GO:0009966 318 0.030
cell growth GO:0016049 104 0.030
regulation of cellular protein metabolic process GO:0032268 267 0.029
cell motility GO:0048870 202 0.028
single organism organelle organization GO:1902589 180 0.028
defense response GO:0006952 194 0.028
cellular response to growth factor stimulus GO:0071363 162 0.027
protein complex subunit organization GO:0071822 302 0.027
cell type specific apoptotic process GO:0097285 134 0.027
negative regulation of cellular metabolic process GO:0031324 281 0.026
regulation of catalytic activity GO:0050790 304 0.026
purine ribonucleotide catabolic process GO:0009154 136 0.026
homeostatic process GO:0042592 331 0.026
positive regulation of neurogenesis GO:0050769 165 0.026
positive regulation of hydrolase activity GO:0051345 86 0.025
regulation of cellular amine metabolic process GO:0033238 8 0.025
metal ion transport GO:0030001 289 0.025
organic cyclic compound catabolic process GO:1901361 175 0.025
double strand break repair GO:0006302 1 0.025
regulation of intracellular signal transduction GO:1902531 218 0.025
cellular component biogenesis GO:0044085 368 0.025
regulation of cellular ketone metabolic process GO:0010565 27 0.025
regulation of cell projection organization GO:0031344 175 0.025
cellular ketone metabolic process GO:0042180 51 0.024
action potential GO:0001508 54 0.024
guanosine containing compound metabolic process GO:1901068 74 0.024
purine nucleoside metabolic process GO:0042278 169 0.024
protein complex assembly GO:0006461 263 0.024
carbohydrate derivative catabolic process GO:1901136 147 0.024
response to decreased oxygen levels GO:0036293 237 0.024
regulation of cell proliferation GO:0042127 359 0.024
macromolecular complex subunit organization GO:0043933 339 0.024
amine metabolic process GO:0009308 38 0.024
negative regulation of metabolic process GO:0009892 331 0.024
central nervous system development GO:0007417 311 0.024
positive regulation of signal transduction GO:0009967 175 0.024
negative regulation of neuron death GO:1901215 69 0.023
positive regulation of apoptotic process GO:0043065 154 0.023
positive regulation of catalytic activity GO:0043085 184 0.023
regulation of programmed cell death GO:0043067 341 0.023
aromatic compound catabolic process GO:0019439 168 0.023
positive regulation of neuron projection development GO:0010976 99 0.023
regulation of proteasomal protein catabolic process GO:0061136 4 0.023
nucleoside metabolic process GO:0009116 179 0.022
intracellular transport GO:0046907 185 0.022
regulation of protein metabolic process GO:0051246 289 0.022
gonad development GO:0008406 104 0.022
purine containing compound metabolic process GO:0072521 253 0.022
glycosyl compound metabolic process GO:1901657 182 0.022
rna metabolic process GO:0016070 406 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.022
cellular response to oxygen containing compound GO:1901701 386 0.021
axon development GO:0061564 96 0.021
negative regulation of molecular function GO:0044092 133 0.021
cellular component morphogenesis GO:0032989 155 0.021
growth GO:0040007 165 0.021
transcription from rna polymerase ii promoter GO:0006366 252 0.021
positive regulation of catabolic process GO:0009896 78 0.021
response to other organism GO:0051707 220 0.021
protein complex biogenesis GO:0070271 263 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.021
nucleotide metabolic process GO:0009117 279 0.021
cell fate determination GO:0001709 2 0.020
regulation of rna biosynthetic process GO:2001141 381 0.020
response to metal ion GO:0010038 253 0.020
cellular macromolecular complex assembly GO:0034622 58 0.020
positive regulation of cell death GO:0010942 184 0.019
positive regulation of cellular catabolic process GO:0031331 71 0.019
cell projection morphogenesis GO:0048858 123 0.019
regulation of response to external stimulus GO:0032101 106 0.019
protein heterooligomerization GO:0051291 89 0.019
purine ribonucleoside catabolic process GO:0046130 124 0.019
regulation of purine nucleotide metabolic process GO:1900542 115 0.019
enzyme linked receptor protein signaling pathway GO:0007167 116 0.019
axon cargo transport GO:0008088 1 0.019
ribonucleoside triphosphate catabolic process GO:0009203 122 0.019
ribonucleotide catabolic process GO:0009261 136 0.019
response to growth factor GO:0070848 189 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
regulation of anatomical structure morphogenesis GO:0022603 141 0.018
immune system process GO:0002376 204 0.018
response to glucocorticoid GO:0051384 223 0.018
single organism reproductive process GO:0044702 297 0.018
organelle localization GO:0051640 55 0.018
cellular macromolecule localization GO:0070727 122 0.018
regulation of nervous system development GO:0051960 264 0.018
positive regulation of programmed cell death GO:0043068 157 0.018
cell cell signaling GO:0007267 335 0.018
ion transmembrane transport GO:0034220 365 0.018
regulation of anatomical structure size GO:0090066 135 0.018
protein localization to organelle GO:0033365 57 0.018
negative regulation of phosphorus metabolic process GO:0010563 80 0.018
positive regulation of cellular biosynthetic process GO:0031328 295 0.018
multi multicellular organism process GO:0044706 138 0.018
negative regulation of cell cycle phase transition GO:1901988 4 0.018
regulation of gtpase activity GO:0043087 57 0.018
single organism catabolic process GO:0044712 283 0.018
cellular component assembly GO:0022607 360 0.017
transmembrane transport GO:0055085 412 0.017
regulation of cell development GO:0060284 263 0.017
carboxylic acid metabolic process GO:0019752 289 0.017
regulation of protein localization GO:0032880 81 0.017
ribonucleotide metabolic process GO:0009259 231 0.017
developmental growth GO:0048589 100 0.017
negative regulation of cellular protein metabolic process GO:0032269 106 0.017
regulation of protein phosphorylation GO:0001932 183 0.017
positive regulation of nucleoside metabolic process GO:0045979 55 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.017
proteolysis GO:0006508 175 0.017
cellular response to external stimulus GO:0071496 118 0.017
gtp catabolic process GO:0006184 71 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.017
cellular nitrogen compound catabolic process GO:0044270 163 0.017
cellular amino acid metabolic process GO:0006520 107 0.017
asymmetric protein localization GO:0008105 2 0.016
cellular response to oxidative stress GO:0034599 76 0.016
regulation of neuron differentiation GO:0045664 208 0.016
ribonucleoside triphosphate metabolic process GO:0009199 141 0.016
negative regulation of protein metabolic process GO:0051248 114 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
cell cycle checkpoint GO:0000075 2 0.016
purine containing compound catabolic process GO:0072523 138 0.016
response to nutrient GO:0007584 248 0.016
regulation of cell differentiation GO:0045595 320 0.016
regulation of protein kinase activity GO:0045859 105 0.016
mapk cascade GO:0000165 140 0.016
response to transition metal nanoparticle GO:1990267 122 0.016
nucleoside catabolic process GO:0009164 126 0.016
macromolecule localization GO:0033036 252 0.016
apoptotic process GO:0006915 381 0.016
regulation of kinase activity GO:0043549 117 0.016
regulation of axonogenesis GO:0050770 37 0.016
taxis GO:0042330 67 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
positive regulation of phosphorylation GO:0042327 177 0.015
reproductive process GO:0022414 372 0.015
synaptic transmission GO:0007268 235 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
negative regulation of phosphate metabolic process GO:0045936 80 0.015
regulation of meiotic cell cycle GO:0051445 3 0.015
single organism cellular localization GO:1902580 102 0.015
organic acid metabolic process GO:0006082 292 0.015
regulation of transferase activity GO:0051338 123 0.015
regulation of mapk cascade GO:0043408 116 0.015
aging GO:0007568 241 0.015
regulation of nucleoside metabolic process GO:0009118 66 0.015
regulation of apoptotic process GO:0042981 335 0.015
protein autophosphorylation GO:0046777 66 0.015
regulation of cell morphogenesis GO:0022604 77 0.015
regulation of nucleotide metabolic process GO:0006140 117 0.015
nucleobase containing small molecule metabolic process GO:0055086 316 0.015
regulation of membrane potential GO:0042391 110 0.015
response to ketone GO:1901654 182 0.015
organophosphate catabolic process GO:0046434 148 0.015
ribose phosphate metabolic process GO:0019693 235 0.015
heterocycle catabolic process GO:0046700 167 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
signal transduction by phosphorylation GO:0023014 144 0.014
multicellular organism reproduction GO:0032504 233 0.014
immune response GO:0006955 104 0.014
regulation of cell growth GO:0001558 85 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
intracellular protein transport GO:0006886 79 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.014
actin cytoskeleton organization GO:0030036 73 0.014
nucleoside phosphate catabolic process GO:1901292 140 0.014
response to peptide GO:1901652 292 0.014
cell projection organization GO:0030030 302 0.014
regulation of organelle organization GO:0033043 80 0.014
response to radiation GO:0009314 137 0.014
gtp metabolic process GO:0046039 72 0.014
vesicle mediated transport GO:0016192 181 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.014
chromosome organization GO:0051276 36 0.014
regulation of multicellular organismal development GO:2000026 376 0.013
reproductive system development GO:0061458 128 0.013
establishment of protein localization GO:0045184 141 0.013
negative regulation of innate immune response GO:0045824 4 0.013
axis specification GO:0009798 4 0.013
regulation of phosphatidylinositol dephosphorylation GO:0060304 1 0.013
regulation of locomotion GO:0040012 148 0.013
regulation of dendrite morphogenesis GO:0048814 33 0.013
negative regulation of protein phosphorylation GO:0001933 44 0.013
response to hydrogen peroxide GO:0042542 89 0.013
erk1 and erk2 cascade GO:0070371 48 0.013
macromolecule catabolic process GO:0009057 58 0.013
multicellular organism growth GO:0035264 1 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
regulation of dna metabolic process GO:0051052 60 0.013
positive regulation of phosphorus metabolic process GO:0010562 262 0.013
cellular response to extracellular stimulus GO:0031668 73 0.013
nucleoside triphosphate catabolic process GO:0009143 123 0.013
purine ribonucleoside metabolic process GO:0046128 168 0.013
cellular response to oxygen levels GO:0071453 60 0.013
response to peptide hormone GO:0043434 278 0.013
negative regulation of proteolysis GO:0045861 41 0.013
response to chromate GO:0046687 3 0.013
regulation of cytoskeleton organization GO:0051493 49 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.012
nucleoside triphosphate metabolic process GO:0009141 144 0.012
regulation of nucleotide catabolic process GO:0030811 65 0.012
purine nucleoside triphosphate metabolic process GO:0009144 141 0.012
neuron apoptotic process GO:0051402 88 0.012
gastrulation GO:0007369 2 0.012
regulation of response to stress GO:0080134 126 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
regulation of map kinase activity GO:0043405 53 0.012
protein processing GO:0016485 68 0.012
oxidation reduction process GO:0055114 304 0.012
nucleotide catabolic process GO:0009166 139 0.012
brain development GO:0007420 247 0.012
apoptotic signaling pathway GO:0097190 27 0.012
response to external biotic stimulus GO:0043207 221 0.012
nitrogen compound transport GO:0071705 229 0.012
regulation of growth GO:0040008 105 0.012
protein localization to nucleus GO:0034504 39 0.012
negative regulation of catalytic activity GO:0043086 103 0.011
neuronal action potential GO:0019228 35 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
positive regulation of dendrite morphogenesis GO:0050775 21 0.011
positive regulation of map kinase activity GO:0043406 46 0.011
cellular response to steroid hormone stimulus GO:0071383 93 0.011
development of primary sexual characteristics GO:0045137 107 0.011
developmental process involved in reproduction GO:0003006 159 0.011
sex differentiation GO:0007548 113 0.011
multicellular organismal reproductive process GO:0048609 233 0.011
positive regulation of protein modification process GO:0031401 142 0.011
negative regulation of cell communication GO:0010648 158 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
multicellular organismal signaling GO:0035637 44 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
axonogenesis GO:0007409 71 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
ras protein signal transduction GO:0007265 29 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
peptide biosynthetic process GO:0043043 3 0.011
cytoskeleton organization GO:0007010 111 0.011
cellular homeostasis GO:0019725 252 0.011
negative regulation of gene expression GO:0010629 199 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
actin filament based process GO:0030029 86 0.011
negative regulation of neuron apoptotic process GO:0043524 45 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.010
cellular response to alcohol GO:0097306 87 0.010
wound healing GO:0042060 122 0.010
morphogenesis of a polarized epithelium GO:0001738 1 0.010
eye development GO:0001654 50 0.010
positive regulation of mapk cascade GO:0043410 92 0.010
mitotic cell cycle checkpoint GO:0007093 1 0.010
gliogenesis GO:0042063 93 0.010
response to vitamin GO:0033273 131 0.010
regulation of neuron apoptotic process GO:0043523 83 0.010
regulation of developmental growth GO:0048638 45 0.010
organelle fission GO:0048285 25 0.010
cytoplasmic transport GO:0016482 115 0.010
mitotic cell cycle phase transition GO:0044772 20 0.010
positive regulation of biosynthetic process GO:0009891 319 0.010
biological adhesion GO:0022610 110 0.010

Dctn2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
disease of cellular proliferation DOID:14566 0 0.017
cancer DOID:162 0 0.016
organ system cancer DOID:0050686 0 0.016