Rattus norvegicus

13 known processes

Ddr1

discoidin domain receptor tyrosine kinase 1

(Aliases: Cak,PTK3D,Drd1)

Ddr1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell proliferation GO:0042127 359 0.820
Mouse
cell motility GO:0048870 202 0.633
Human Mouse
localization of cell GO:0051674 202 0.629
Human Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.607
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.553
regulation of programmed cell death GO:0043067 341 0.550
cellular component movement GO:0006928 248 0.542
Human Mouse
regulation of nucleic acid templated transcription GO:1903506 380 0.502
positive regulation of cell proliferation GO:0008284 249 0.500
transcription dna templated GO:0006351 377 0.470
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.468
regulation of transcription dna templated GO:0006355 374 0.463
reproductive process GO:0022414 372 0.448
Mouse
negative regulation of cell communication GO:0010648 158 0.438
positive regulation of signaling GO:0023056 270 0.432
regulation of rna metabolic process GO:0051252 391 0.394
negative regulation of signaling GO:0023057 157 0.393
positive regulation of signal transduction GO:0009967 175 0.376
regulation of signal transduction GO:0009966 318 0.374
negative regulation of cell death GO:0060548 229 0.368
negative regulation of cell proliferation GO:0008285 119 0.362
Mouse
response to oxygen levels GO:0070482 265 0.357
regulation of rna biosynthetic process GO:2001141 381 0.354
positive regulation of transcription dna templated GO:0045893 197 0.347
cell cell signaling GO:0007267 335 0.334
positive regulation of rna biosynthetic process GO:1902680 197 0.332
nucleic acid templated transcription GO:0097659 379 0.320
negative regulation of response to stimulus GO:0048585 155 0.314
positive regulation of phosphorus metabolic process GO:0010562 262 0.300
rna metabolic process GO:0016070 406 0.297
protein complex subunit organization GO:0071822 302 0.292
response to nutrient GO:0007584 248 0.281
regulation of phosphorus metabolic process GO:0051174 349 0.273
lipid metabolic process GO:0006629 283 0.270
positive regulation of multicellular organismal process GO:0051240 387 0.268
negative regulation of programmed cell death GO:0043069 183 0.264
regulation of catalytic activity GO:0050790 304 0.256
head development GO:0060322 247 0.249
development of primary sexual characteristics GO:0045137 107 0.248
protein complex assembly GO:0006461 263 0.248
regulation of neural precursor cell proliferation GO:2000177 16 0.242
positive regulation of rna metabolic process GO:0051254 203 0.229
negative regulation of developmental process GO:0051093 125 0.226
myelination GO:0042552 39 0.225
response to molecule of bacterial origin GO:0002237 194 0.224
multi organism reproductive process GO:0044703 262 0.222
Mouse
positive regulation of response to stimulus GO:0048584 285 0.221
locomotion GO:0040011 237 0.221
Human Mouse
axon guidance GO:0007411 24 0.220
transcription from rna polymerase ii promoter GO:0006366 252 0.217
regulation of nervous system development GO:0051960 264 0.213
regulation of intracellular signal transduction GO:1902531 218 0.212
signal transduction by phosphorylation GO:0023014 144 0.211
positive regulation of intracellular signal transduction GO:1902533 138 0.207
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.206
ensheathment of neurons GO:0007272 40 0.200
response to estrogen GO:0043627 232 0.196
immune effector process GO:0002252 53 0.196
single organism reproductive process GO:0044702 297 0.195
Mouse
central nervous system development GO:0007417 311 0.194
positive regulation of neurogenesis GO:0050769 165 0.188
neuron death GO:0070997 127 0.185
negative regulation of cellular metabolic process GO:0031324 281 0.182
regulation of phosphate metabolic process GO:0019220 349 0.180
forebrain development GO:0030900 98 0.177
immune response GO:0006955 104 0.171
intracellular signal transduction GO:0035556 314 0.169
endocytosis GO:0006897 84 0.167
regulation of lipid metabolic process GO:0019216 68 0.167
negative regulation of multicellular organismal process GO:0051241 203 0.166
regulation of neuron death GO:1901214 115 0.165
negative regulation of apoptotic process GO:0043066 181 0.165
cell projection organization GO:0030030 302 0.161
negative regulation of molecular function GO:0044092 133 0.159
negative regulation of kidney development GO:0090185 2 0.157
cell type specific apoptotic process GO:0097285 134 0.157
positive regulation of gene expression GO:0010628 244 0.155
aging GO:0007568 241 0.155
chemical homeostasis GO:0048878 292 0.153
multicellular organismal signaling GO:0035637 44 0.151
aromatic compound catabolic process GO:0019439 168 0.149
regulation of molecular function GO:0065009 398 0.149
response to peptide hormone GO:0043434 278 0.148
response to corticosteroid GO:0031960 235 0.148
synaptic transmission GO:0007268 235 0.148
actin filament bundle organization GO:0061572 19 0.147
regulation of apoptotic process GO:0042981 335 0.147
organophosphate metabolic process GO:0019637 370 0.146
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.142
positive regulation of cellular biosynthetic process GO:0031328 295 0.142
positive regulation of cell communication GO:0010647 271 0.141
cell activation GO:0001775 97 0.138
purine nucleotide catabolic process GO:0006195 136 0.137
programmed cell death GO:0012501 392 0.135
cellular response to oxygen containing compound GO:1901701 386 0.134
regulation of synaptic transmission GO:0050804 141 0.133
nucleotide metabolic process GO:0009117 279 0.133
secretion GO:0046903 307 0.130
gliogenesis GO:0042063 93 0.130
response to external biotic stimulus GO:0043207 221 0.130
regulation of cell migration GO:0030334 128 0.128
purine containing compound metabolic process GO:0072521 253 0.127
organophosphate catabolic process GO:0046434 148 0.125
response to biotic stimulus GO:0009607 226 0.125
positive regulation of cell differentiation GO:0045597 217 0.124
cell migration GO:0016477 197 0.124
Human Mouse
positive regulation of catalytic activity GO:0043085 184 0.123
axonogenesis GO:0007409 71 0.122
positive regulation of nucleic acid templated transcription GO:1903508 197 0.122
regulation of cell differentiation GO:0045595 320 0.121
carbohydrate derivative catabolic process GO:1901136 147 0.120
cell projection morphogenesis GO:0048858 123 0.120
purine ribonucleotide metabolic process GO:0009150 227 0.120
phosphatidylinositol 3 kinase signaling GO:0014065 14 0.119
response to decreased oxygen levels GO:0036293 237 0.118
gland development GO:0048732 155 0.117
Mouse
positive regulation of phosphate metabolic process GO:0045937 262 0.116
nucleobase containing small molecule metabolic process GO:0055086 316 0.116
nucleoside phosphate metabolic process GO:0006753 283 0.116
carbohydrate derivative metabolic process GO:1901135 346 0.115
rhythmic process GO:0048511 156 0.115
ribonucleotide metabolic process GO:0009259 231 0.115
ribonucleoside metabolic process GO:0009119 174 0.114
response to hypoxia GO:0001666 231 0.113
positive regulation of nucleoside metabolic process GO:0045979 55 0.113
regulation of cell motility GO:2000145 131 0.112
vesicle mediated transport GO:0016192 181 0.109
organelle organization GO:0006996 266 0.108
neuron apoptotic process GO:0051402 88 0.107
purine nucleoside catabolic process GO:0006152 124 0.106
glial cell differentiation GO:0010001 65 0.106
response to cytokine GO:0034097 215 0.105
negative regulation of neuron apoptotic process GO:0043524 45 0.105
regulation of cell development GO:0060284 263 0.104
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.104
reproductive system development GO:0061458 128 0.104
ribonucleotide catabolic process GO:0009261 136 0.103
regulation of kinase activity GO:0043549 117 0.102
negative regulation of metabolic process GO:0009892 331 0.102
gonad development GO:0008406 104 0.102
cellular response to hormone stimulus GO:0032870 247 0.102
regeneration GO:0031099 163 0.102
cellular component assembly GO:0022607 360 0.101
phototransduction visible light GO:0007603 2 0.100
telencephalon development GO:0021537 62 0.099
response to acid chemical GO:0001101 222 0.099
mesonephric tubule development GO:0072164 14 0.099
enzyme linked receptor protein signaling pathway GO:0007167 116 0.096
Human Mouse
rna biosynthetic process GO:0032774 380 0.096
negative regulation of nervous system development GO:0051961 79 0.095
axon development GO:0061564 96 0.095
catabolic process GO:0009056 351 0.095
regulation of secretion by cell GO:1903530 208 0.095
negative regulation of cell differentiation GO:0045596 99 0.094
purine nucleoside triphosphate metabolic process GO:0009144 141 0.094
regulation of vesicle mediated transport GO:0060627 81 0.094
regulation of multicellular organismal development GO:2000026 376 0.093
ribonucleoside triphosphate catabolic process GO:0009203 122 0.093
organ morphogenesis GO:0009887 75 0.091
Mouse
multicellular organismal homeostasis GO:0048871 49 0.091
cellular response to organonitrogen compound GO:0071417 197 0.091
positive regulation of developmental process GO:0051094 283 0.091
ribose phosphate metabolic process GO:0019693 235 0.091
regulation of cellular protein metabolic process GO:0032268 267 0.091
peptidyl tyrosine phosphorylation GO:0018108 72 0.090
Human Mouse
positive regulation of nervous system development GO:0051962 178 0.090
purine nucleotide metabolic process GO:0006163 229 0.089
homeostatic process GO:0042592 331 0.089
cellular component biogenesis GO:0044085 368 0.088
brain development GO:0007420 247 0.088
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 5 0.087
response to peptide GO:1901652 292 0.087
alpha beta t cell differentiation GO:0046632 2 0.086
regulation of cellular localization GO:0060341 263 0.086
purine containing compound catabolic process GO:0072523 138 0.085
nucleoside triphosphate catabolic process GO:0009143 123 0.085
macromolecular complex subunit organization GO:0043933 339 0.084
ribonucleoside catabolic process GO:0042454 126 0.084
cell adhesion GO:0007155 110 0.084
Human Mouse
negative regulation of muscle cell apoptotic process GO:0010656 21 0.083
single organism organelle organization GO:1902589 180 0.083
response to bacterium GO:0009617 200 0.083
regulation of cellular component organization GO:0051128 368 0.083
Human Mouse
negative regulation of signal transduction GO:0009968 83 0.082
glycosyl compound catabolic process GO:1901658 126 0.082
regulation of membrane potential GO:0042391 110 0.082
response to mechanical stimulus GO:0009612 134 0.082
response to inorganic substance GO:0010035 377 0.082
cellular homeostasis GO:0019725 252 0.081
reproductive structure development GO:0048608 128 0.081
regulation of neuron differentiation GO:0045664 208 0.081
positive regulation of cell development GO:0010720 176 0.080
cellular ketone metabolic process GO:0042180 51 0.080
positive regulation of nucleotide metabolic process GO:0045981 91 0.080
positive regulation of cell motility GO:2000147 97 0.080
neuron development GO:0048666 286 0.079
regulation of neurogenesis GO:0050767 247 0.079
cellular response to nitrogen compound GO:1901699 210 0.078
anatomical structure formation involved in morphogenesis GO:0048646 83 0.078
regulation of protein metabolic process GO:0051246 289 0.077
immune system process GO:0002376 204 0.076
ribonucleoside triphosphate metabolic process GO:0009199 141 0.076
neuron differentiation GO:0030182 368 0.076
anatomical structure morphogenesis GO:0009653 298 0.076
Human Mouse
axon ensheathment GO:0008366 40 0.075
hormone secretion GO:0046879 115 0.075
positive regulation of biosynthetic process GO:0009891 319 0.074
regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003339 2 0.074
mammary gland involution GO:0060056 5 0.073
purine nucleoside metabolic process GO:0042278 169 0.072
cellular amino acid metabolic process GO:0006520 107 0.072
multi multicellular organism process GO:0044706 138 0.072
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.072
signal transduction in absence of ligand GO:0038034 5 0.071
developmental process involved in reproduction GO:0003006 159 0.071
regulation of nucleotide metabolic process GO:0006140 117 0.071
membrane organization GO:0061024 94 0.071
glial cell development GO:0021782 19 0.070
renal system development GO:0072001 67 0.070
leukocyte activation GO:0045321 76 0.070
positive regulation of cellular component organization GO:0051130 200 0.069
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.068
mesenchymal to epithelial transition GO:0060231 3 0.068
regulation of epithelial cell differentiation GO:0030856 12 0.068
hepaticobiliary system development GO:0061008 90 0.067
negative regulation of neuron death GO:1901215 69 0.066
response to extracellular stimulus GO:0009991 380 0.066
response to ethanol GO:0045471 162 0.066
neuron projection guidance GO:0097485 24 0.065
liver development GO:0001889 90 0.065
single organism intracellular transport GO:1902582 166 0.064
cytokine production GO:0001816 61 0.064
negative regulation of endopeptidase activity GO:0010951 36 0.064
regulation of hydrolase activity GO:0051336 143 0.063
negative regulation of transport GO:0051051 136 0.063
regulation of cellular amino acid metabolic process GO:0006521 2 0.063
cellular response to peptide hormone stimulus GO:0071375 120 0.063
neuron projection development GO:0031175 273 0.062
cytoskeleton organization GO:0007010 111 0.062
apoptotic process GO:0006915 381 0.062
regulation of cell cycle GO:0051726 73 0.062
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.061
nucleoside metabolic process GO:0009116 179 0.061
cellular response to endogenous stimulus GO:0071495 377 0.061
muscle system process GO:0003012 115 0.061
response to wounding GO:0009611 254 0.061
Human Mouse
response to reactive oxygen species GO:0000302 120 0.061
sex differentiation GO:0007548 113 0.060
hormone transport GO:0009914 121 0.060
response to lipopolysaccharide GO:0032496 191 0.060
positive regulation of cellular amine metabolic process GO:0033240 3 0.060
nucleobase containing compound catabolic process GO:0034655 152 0.060
positive regulation of cellular component movement GO:0051272 102 0.059
circulatory system development GO:0072359 134 0.059
small gtpase mediated signal transduction GO:0007264 36 0.059
regulation of hormone levels GO:0010817 187 0.059
macromolecule localization GO:0033036 252 0.059
t cell activation GO:0042110 29 0.059
regulation of catabolic process GO:0009894 113 0.059
response to retinoic acid GO:0032526 63 0.058
positive regulation of molecular function GO:0044093 230 0.058
nucleotide catabolic process GO:0009166 139 0.058
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.057
circadian rhythm GO:0007623 88 0.057
regulation of establishment of protein localization GO:0070201 69 0.056
purine ribonucleoside catabolic process GO:0046130 124 0.056
response to estradiol GO:0032355 164 0.056
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.055
cognition GO:0050890 92 0.055
positive regulation of protein metabolic process GO:0051247 178 0.055
g protein coupled receptor signaling pathway GO:0007186 242 0.055
positive regulation of secretion by cell GO:1903532 128 0.055
female pregnancy GO:0007565 122 0.054
Mouse
calcium ion homeostasis GO:0055074 162 0.054
behavior GO:0007610 205 0.054
kidney epithelium development GO:0072073 19 0.054
nitrogen compound transport GO:0071705 229 0.053
regulation of transferase activity GO:0051338 123 0.053
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.053
ureteric bud development GO:0001657 14 0.053
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.053
positive regulation of cell migration GO:0030335 96 0.051
neuron projection morphogenesis GO:0048812 122 0.050
cellular response to peptide GO:1901653 133 0.050
cell cycle GO:0007049 101 0.050
urogenital system development GO:0001655 78 0.050
cellular component morphogenesis GO:0032989 155 0.050
digestive system development GO:0055123 41 0.049
actomyosin structure organization GO:0031032 22 0.049
negative regulation of gene expression GO:0010629 199 0.049
negative regulation of macromolecule metabolic process GO:0010605 260 0.049
cytokine mediated signaling pathway GO:0019221 43 0.048
nucleoside monophosphate metabolic process GO:0009123 93 0.048
ribonucleotide biosynthetic process GO:0009260 85 0.048
regulation of phosphorylation GO:0042325 248 0.048
growth GO:0040007 165 0.048
Mouse
regulation of cellular amine metabolic process GO:0033238 8 0.047
mammary gland development GO:0030879 38 0.047
Mouse
transmission of nerve impulse GO:0019226 42 0.047
nucleoside catabolic process GO:0009164 126 0.047
purine nucleoside triphosphate catabolic process GO:0009146 122 0.047
positive regulation of mitochondrion organization GO:0010822 4 0.046
negative regulation of cell development GO:0010721 82 0.046
response to oxidative stress GO:0006979 186 0.046
signal release GO:0023061 145 0.045
regulation of peptide hormone secretion GO:0090276 80 0.045
protein transport GO:0015031 132 0.045
cellular response to stress GO:0033554 269 0.045
regulation of hormone secretion GO:0046883 106 0.045
cell morphogenesis GO:0000902 142 0.044
negative regulation of cellular biosynthetic process GO:0031327 161 0.044
neural crest cell differentiation GO:0014033 2 0.043
positive regulation of immune system process GO:0002684 90 0.043
regulation of synaptic plasticity GO:0048167 70 0.043
neuronal action potential GO:0019228 35 0.043
regulation of metal ion transport GO:0010959 118 0.043
action potential GO:0001508 54 0.043
response to hexose GO:0009746 144 0.043
cellular nitrogen compound catabolic process GO:0044270 163 0.042
mammary gland morphogenesis GO:0060443 6 0.042
Mouse
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.042
nucleoside phosphate catabolic process GO:1901292 140 0.042
regulation of neuron apoptotic process GO:0043523 83 0.041
regulation of purine nucleotide metabolic process GO:1900542 115 0.041
choline transport GO:0015871 4 0.041
response to insulin GO:0032868 133 0.040
positive regulation of hydrolase activity GO:0051345 86 0.040
positive regulation of protein kinase b signaling GO:0051897 10 0.040
response to hydrogen peroxide GO:0042542 89 0.040
regulation of cellular ketone metabolic process GO:0010565 27 0.040
response to axon injury GO:0048678 59 0.040
defense response GO:0006952 194 0.039
cellular response to lipid GO:0071396 201 0.039
regulation of cellular catabolic process GO:0031329 101 0.039
negative regulation of protein metabolic process GO:0051248 114 0.039
retinal ganglion cell axon guidance GO:0031290 1 0.039
lipid localization GO:0010876 62 0.038
odontogenesis GO:0042476 32 0.038
cardiovascular system development GO:0072358 134 0.038
glycosyl compound metabolic process GO:1901657 182 0.038
intracellular transport GO:0046907 185 0.038
kidney development GO:0001822 67 0.038
tissue development GO:0009888 252 0.038
Human Mouse
cellular chemical homeostasis GO:0055082 247 0.038
negative regulation of transcription dna templated GO:0045892 116 0.038
response to metal ion GO:0010038 253 0.037
regulation of platelet derived growth factor receptor signaling pathway GO:0010640 2 0.037
regulation of system process GO:0044057 208 0.037
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.037
single organism catabolic process GO:0044712 283 0.037
morphogenesis of an epithelium GO:0002009 20 0.036
Human Mouse
positive regulation of phosphorylation GO:0042327 177 0.036
protein processing GO:0016485 68 0.036
guanosine containing compound metabolic process GO:1901068 74 0.036
positive regulation of cytokine production GO:0001819 42 0.035
response to tumor necrosis factor GO:0034612 56 0.035
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.035
actin filament based process GO:0030029 86 0.035
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 14 0.035
organonitrogen compound catabolic process GO:1901565 179 0.035
response to other organism GO:0051707 220 0.035
neurological system process GO:0050877 219 0.034
cellular response to insulin stimulus GO:0032869 81 0.034
atp metabolic process GO:0046034 72 0.034
metal ion homeostasis GO:0055065 186 0.034
ras protein signal transduction GO:0007265 29 0.034
negative regulation of rna biosynthetic process GO:1902679 118 0.034
positive regulation of kinase activity GO:0033674 77 0.034
secretion by cell GO:0032940 248 0.033
reproduction GO:0000003 245 0.033
establishment of protein localization GO:0045184 141 0.033
ribonucleoside monophosphate metabolic process GO:0009161 88 0.033
potassium ion transport GO:0006813 97 0.033
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.033
cellular response to growth factor stimulus GO:0071363 162 0.033
developmental growth GO:0048589 100 0.033
regulation of cholesterol metabolic process GO:0090181 5 0.033
cellular amine metabolic process GO:0044106 38 0.033
regulation of cellular component movement GO:0051270 150 0.033
negative regulation of biosynthetic process GO:0009890 168 0.032
protein complex biogenesis GO:0070271 263 0.032
heterocycle catabolic process GO:0046700 167 0.032
nucleoside triphosphate metabolic process GO:0009141 144 0.032
actin filament bundle assembly GO:0051017 19 0.032
retinoic acid receptor signaling pathway GO:0048384 7 0.032
actin filament organization GO:0007015 42 0.032
macromolecular complex assembly GO:0065003 273 0.032
response to carbohydrate GO:0009743 183 0.031
lymphocyte activation GO:0046649 43 0.031
regulation of apoptotic signaling pathway GO:2001233 13 0.031
salivary gland development GO:0007431 3 0.031
organic acid transport GO:0015849 116 0.031
response to growth factor GO:0070848 189 0.031
ossification GO:0001503 70 0.031
neural crest cell development GO:0014032 2 0.030
chemotaxis GO:0006935 66 0.030
muscle contraction GO:0006936 88 0.030
cellular cation homeostasis GO:0030003 180 0.030
multicellular organismal reproductive process GO:0048609 233 0.030
regulation of muscle cell apoptotic process GO:0010660 26 0.030
ion homeostasis GO:0050801 212 0.029
positive regulation of mapk cascade GO:0043410 92 0.029
proteolysis GO:0006508 175 0.029
actin cytoskeleton organization GO:0030036 73 0.029
regulation of metanephros development GO:0072215 4 0.029
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.029
cellular calcium ion homeostasis GO:0006874 160 0.029
positive regulation of cellular protein metabolic process GO:0032270 167 0.029
regulation of endocytosis GO:0030100 42 0.029
mapk cascade GO:0000165 140 0.029
regulation of secretion GO:0051046 224 0.029
divalent inorganic cation homeostasis GO:0072507 165 0.029
renal vesicle morphogenesis GO:0072077 4 0.029
muscle cell migration GO:0014812 36 0.028
Human Mouse
metanephros morphogenesis GO:0003338 6 0.028
astrocyte development GO:0014002 4 0.028
spinal cord development GO:0021510 27 0.028
synaptic growth at neuromuscular junction GO:0051124 1 0.028
response to monosaccharide GO:0034284 159 0.028
negative regulation of catalytic activity GO:0043086 103 0.028
neural crest cell migration GO:0001755 1 0.028
cation homeostasis GO:0055080 195 0.028
positive regulation of neuron differentiation GO:0045666 126 0.028
oxidation reduction process GO:0055114 304 0.028
positive regulation of immune response GO:0050778 42 0.027
intracellular receptor signaling pathway GO:0030522 35 0.027
multicellular organism reproduction GO:0032504 233 0.027
negative regulation of secretion GO:0051048 82 0.027
positive regulation of fc receptor mediated stimulatory signaling pathway GO:0060369 1 0.027
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 1 0.027
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.027
cation transmembrane transport GO:0098655 263 0.027
gland morphogenesis GO:0022612 12 0.027
Mouse
cellular lipid metabolic process GO:0044255 208 0.027
cell morphogenesis involved in differentiation GO:0000904 119 0.027
l alpha amino acid transmembrane transport GO:1902475 15 0.027
regulation of homeostatic process GO:0032844 101 0.026
mesonephros development GO:0001823 14 0.026
purine ribonucleotide catabolic process GO:0009154 136 0.026
regulation of body fluid levels GO:0050878 90 0.026
glucose homeostasis GO:0042593 75 0.026
carboxylic acid metabolic process GO:0019752 289 0.026
regulation of protein maturation GO:1903317 50 0.026
regulation of extrinsic apoptotic signaling pathway GO:2001236 7 0.026
heart morphogenesis GO:0003007 3 0.026
regulation of protein transport GO:0051223 68 0.025
response to nutrient levels GO:0031667 370 0.025
regulation of anatomical structure morphogenesis GO:0022603 141 0.025
negative regulation of phosphate metabolic process GO:0045936 80 0.025
single organism behavior GO:0044708 130 0.025
cell matrix adhesion GO:0007160 19 0.025
Human Mouse
negative regulation of rna metabolic process GO:0051253 123 0.025
immune response regulating signaling pathway GO:0002764 19 0.025
actin filament based movement GO:0030048 16 0.025
cation transport GO:0006812 382 0.025
renal vesicle development GO:0072087 4 0.025
regulation of mapk cascade GO:0043408 116 0.025
hematopoietic progenitor cell differentiation GO:0002244 2 0.025
protein maturation GO:0051604 68 0.024
response to light stimulus GO:0009416 52 0.024
vitamin d receptor signaling pathway GO:0070561 1 0.024
macromolecule catabolic process GO:0009057 58 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.024
Human Mouse
neuron fate commitment GO:0048663 4 0.024
positive regulation of neural precursor cell proliferation GO:2000179 10 0.023
negative regulation of nucleic acid templated transcription GO:1903507 117 0.023
negative regulation of pancreatic stellate cell proliferation GO:2000230 1 0.023
regulation of peptidase activity GO:0052547 55 0.023
cellular response to tumor necrosis factor GO:0071356 46 0.023
purine ribonucleoside metabolic process GO:0046128 168 0.023
amine metabolic process GO:0009308 38 0.023
negative regulation of neurogenesis GO:0050768 78 0.023
heart valve morphogenesis GO:0003179 1 0.023
inositol lipid mediated signaling GO:0048017 18 0.022
dendrite morphogenesis GO:0048813 43 0.022
exocytosis GO:0006887 60 0.022
response to amino acid GO:0043200 75 0.022
organic substance catabolic process GO:1901575 316 0.022
cell part morphogenesis GO:0032990 123 0.022
purine ribonucleotide biosynthetic process GO:0009152 81 0.022
positive regulation of catabolic process GO:0009896 78 0.022
amide transport GO:0042886 105 0.022
phosphatidylinositol mediated signaling GO:0048015 18 0.022
sympathetic nervous system development GO:0048485 1 0.022
purine nucleoside monophosphate metabolic process GO:0009126 84 0.022
monovalent inorganic cation transport GO:0015672 172 0.022
peptidyl tyrosine autophosphorylation GO:0038083 1 0.022
Human
cellular catabolic process GO:0044248 295 0.022
purine nucleoside monophosphate catabolic process GO:0009128 55 0.022
nucleoside phosphate biosynthetic process GO:1901293 102 0.022
activation of protein kinase b activity GO:0032148 3 0.022
response to glucose GO:0009749 136 0.021
cellular response to hexose stimulus GO:0071331 65 0.021

Ddr1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.066
gastrointestinal system disease DOID:77 0 0.066
sensory system disease DOID:0050155 0 0.026
nervous system disease DOID:863 0 0.026