Rattus norvegicus

0 known processes

Ddx46

DEAD (Asp-Glu-Ala-Asp) box polypeptide 46

Ddx46 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
macromolecule localization GO:0033036 252 0.277
negative regulation of metabolic process GO:0009892 331 0.239
synaptic vesicle docking involved in exocytosis GO:0016081 2 0.186
response to nutrient levels GO:0031667 370 0.168
reproductive process GO:0022414 372 0.166
multi multicellular organism process GO:0044706 138 0.165
regulation of cellular protein metabolic process GO:0032268 267 0.139
neuron differentiation GO:0030182 368 0.137
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.130
response to peptide GO:1901652 292 0.130
regulation of molecular function GO:0065009 398 0.128
macromolecular complex subunit organization GO:0043933 339 0.125
reproduction GO:0000003 245 0.122
cellular component biogenesis GO:0044085 368 0.120
cellular component assembly GO:0022607 360 0.120
single organism organelle organization GO:1902589 180 0.112
cellular response to oxygen containing compound GO:1901701 386 0.104
cell cycle GO:0007049 101 0.103
positive regulation of response to stimulus GO:0048584 285 0.099
developmental process involved in reproduction GO:0003006 159 0.097
multicellular organismal reproductive process GO:0048609 233 0.096
negative regulation of cellular metabolic process GO:0031324 281 0.096
regulation of catalytic activity GO:0050790 304 0.096
protein localization GO:0008104 191 0.095
regulation of protein metabolic process GO:0051246 289 0.095
response to peptide hormone GO:0043434 278 0.091
multicellular organism reproduction GO:0032504 233 0.089
catabolic process GO:0009056 351 0.089
Yeast
negative regulation of gene expression GO:0010629 199 0.086
regulation of signal transduction GO:0009966 318 0.084
cellular response to stress GO:0033554 269 0.083
regulation of cell motility GO:2000145 131 0.083
single organism catabolic process GO:0044712 283 0.081
Yeast
organelle organization GO:0006996 266 0.081
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.080
cellular response to external stimulus GO:0071496 118 0.080
single organism reproductive process GO:0044702 297 0.080
response to starvation GO:0042594 59 0.078
protein complex biogenesis GO:0070271 263 0.077
response to oxygen levels GO:0070482 265 0.077
negative regulation of macromolecule metabolic process GO:0010605 260 0.075
rna biosynthetic process GO:0032774 380 0.075
rna metabolic process GO:0016070 406 0.074
Fly
regulation of cellular catabolic process GO:0031329 101 0.073
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.071
positive regulation of multicellular organismal process GO:0051240 387 0.071
peptidyl amino acid modification GO:0018193 126 0.071
head development GO:0060322 247 0.070
chromatin assembly or disassembly GO:0006333 1 0.070
cellular catabolic process GO:0044248 295 0.069
Yeast
regulation of cell proliferation GO:0042127 359 0.066
cellular response to nitrogen compound GO:1901699 210 0.065
response to nutrient GO:0007584 248 0.064
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.064
Fly
multi organism reproductive process GO:0044703 262 0.063
neuron development GO:0048666 286 0.063
anatomical structure morphogenesis GO:0009653 298 0.062
cellular response to endogenous stimulus GO:0071495 377 0.061
regulation of cellular component organization GO:0051128 368 0.061
response to extracellular stimulus GO:0009991 380 0.059
proteolysis GO:0006508 175 0.057
cellular chemical homeostasis GO:0055082 247 0.055
cell projection organization GO:0030030 302 0.054
cellular component movement GO:0006928 248 0.054
regulation of hydrolase activity GO:0051336 143 0.051
response to hypoxia GO:0001666 231 0.050
apoptotic process GO:0006915 381 0.050
protein complex subunit organization GO:0071822 302 0.049
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.048
negative regulation of apoptotic process GO:0043066 181 0.047
response to growth factor GO:0070848 189 0.046
intracellular signal transduction GO:0035556 314 0.046
cell migration GO:0016477 197 0.045
positive regulation of cellular protein metabolic process GO:0032270 167 0.045
transcription dna templated GO:0006351 377 0.045
mitotic cell cycle process GO:1903047 35 0.044
positive regulation of cell proliferation GO:0008284 249 0.044
regulation of locomotion GO:0040012 148 0.044
gonad development GO:0008406 104 0.043
response to biotic stimulus GO:0009607 226 0.041
positive regulation of cellular biosynthetic process GO:0031328 295 0.041
dna metabolic process GO:0006259 96 0.041
regulation of cellular amine metabolic process GO:0033238 8 0.040
response to glucose GO:0009749 136 0.040
protein complex assembly GO:0006461 263 0.040
negative regulation of programmed cell death GO:0043069 183 0.040
cell cell signaling GO:0007267 335 0.039
positive regulation of gene expression GO:0010628 244 0.038
cellular response to peptide GO:1901653 133 0.038
regulation of cellular amino acid metabolic process GO:0006521 2 0.037
regulation of response to stress GO:0080134 126 0.037
negative regulation of developmental process GO:0051093 125 0.037
nucleic acid templated transcription GO:0097659 379 0.037
regulation of cellular ketone metabolic process GO:0010565 27 0.036
aging GO:0007568 241 0.036
sexual reproduction GO:0019953 148 0.036
macroautophagy GO:0016236 4 0.036
neuron projection development GO:0031175 273 0.036
response to decreased oxygen levels GO:0036293 237 0.035
positive regulation of biosynthetic process GO:0009891 319 0.035
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.035
regulation of programmed cell death GO:0043067 341 0.035
nucleosome organization GO:0034728 1 0.035
regulation of intracellular signal transduction GO:1902531 218 0.034
single organism intracellular transport GO:1902582 166 0.034
cellular amino acid metabolic process GO:0006520 107 0.034
positive regulation of transport GO:0051050 245 0.034
establishment of organelle localization GO:0051656 37 0.033
macromolecular complex assembly GO:0065003 273 0.033
gamete generation GO:0007276 124 0.033
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.033
programmed cell death GO:0012501 392 0.033
regulation of response to external stimulus GO:0032101 106 0.032
vesicle mediated transport GO:0016192 181 0.032
regulation of nucleic acid templated transcription GO:1903506 380 0.032
translation GO:0006412 35 0.032
cellular response to organonitrogen compound GO:0071417 197 0.032
organic acid metabolic process GO:0006082 292 0.031
locomotion GO:0040011 237 0.031
spermatogenesis GO:0007283 99 0.031
dna packaging GO:0006323 4 0.031
response to ammonium ion GO:0060359 71 0.031
regulation of cell differentiation GO:0045595 320 0.031
homeostatic process GO:0042592 331 0.030
cellular homeostasis GO:0019725 252 0.030
regulation of cellular localization GO:0060341 263 0.030
cellular response to extracellular stimulus GO:0031668 73 0.030
positive regulation of phosphate metabolic process GO:0045937 262 0.029
response to alkaloid GO:0043279 132 0.029
positive regulation of response to external stimulus GO:0032103 51 0.029
cellular response to hormone stimulus GO:0032870 247 0.029
chemical homeostasis GO:0048878 292 0.028
transcription from rna polymerase ii promoter GO:0006366 252 0.028
regulation of phosphorus metabolic process GO:0051174 349 0.028
response to insulin GO:0032868 133 0.028
positive regulation of cell migration GO:0030335 96 0.028
regulation of multicellular organismal development GO:2000026 376 0.028
negative regulation of rna splicing GO:0033119 3 0.027
regulation of catabolic process GO:0009894 113 0.027
positive regulation of developmental process GO:0051094 283 0.027
histone methylation GO:0016571 3 0.027
positive regulation of protein metabolic process GO:0051247 178 0.026
response to acid chemical GO:0001101 222 0.026
small gtpase mediated signal transduction GO:0007264 36 0.026
male gamete generation GO:0048232 99 0.026
negative regulation of protein metabolic process GO:0051248 114 0.026
positive regulation of molecular function GO:0044093 230 0.026
double strand break repair GO:0006302 1 0.026
response to monosaccharide GO:0034284 159 0.025
amine metabolic process GO:0009308 38 0.025
positive regulation of nervous system development GO:0051962 178 0.025
negative regulation of rna metabolic process GO:0051253 123 0.025
response to carbohydrate GO:0009743 183 0.025
response to vitamin GO:0033273 131 0.025
response to radiation GO:0009314 137 0.025
negative regulation of molecular function GO:0044092 133 0.025
endocytosis GO:0006897 84 0.024
regulation of immune system process GO:0002682 123 0.024
cytoskeleton organization GO:0007010 111 0.024
response to hexose GO:0009746 144 0.024
negative regulation of cellular protein metabolic process GO:0032269 106 0.023
muscle structure development GO:0061061 87 0.023
cellular ketone metabolic process GO:0042180 51 0.023
cell motility GO:0048870 202 0.023
cellular amine metabolic process GO:0044106 38 0.023
response to estradiol GO:0032355 164 0.023
regulation of mrna splicing via spliceosome GO:0048024 3 0.023
Fly
regulation of apoptotic process GO:0042981 335 0.023
negative regulation of nucleic acid templated transcription GO:1903507 117 0.022
receptor mediated endocytosis GO:0006898 42 0.022
protein oligomerization GO:0051259 191 0.022
divalent inorganic cation homeostasis GO:0072507 165 0.022
ribose phosphate metabolic process GO:0019693 235 0.022
Yeast
development of primary sexual characteristics GO:0045137 107 0.022
cation homeostasis GO:0055080 195 0.022
establishment of protein localization GO:0045184 141 0.022
negative regulation of cellular response to insulin stimulus GO:1900077 11 0.021
tissue development GO:0009888 252 0.021
transmembrane transport GO:0055085 412 0.021
growth GO:0040007 165 0.021
reproductive structure development GO:0048608 128 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.021
positive regulation of nucleic acid templated transcription GO:1903508 197 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
protein processing GO:0016485 68 0.021
monovalent inorganic cation transport GO:0015672 172 0.021
cellular response to starvation GO:0009267 27 0.021
positive regulation of rna metabolic process GO:0051254 203 0.021
cellular response to acid chemical GO:0071229 75 0.021
eye morphogenesis GO:0048592 4 0.021
embryo development GO:0009790 49 0.021
regulation of rna biosynthetic process GO:2001141 381 0.020
negative regulation of response to stimulus GO:0048585 155 0.020
carbohydrate derivative metabolic process GO:1901135 346 0.020
Yeast
response to wounding GO:0009611 254 0.020
sex differentiation GO:0007548 113 0.020
ribonucleoside triphosphate metabolic process GO:0009199 141 0.020
Yeast
cellular response to peptide hormone stimulus GO:0071375 120 0.020
regulation of cell migration GO:0030334 128 0.020
insulin receptor signaling pathway GO:0008286 24 0.020
regulation of phosphate metabolic process GO:0019220 349 0.019
cytoplasmic transport GO:0016482 115 0.019
regulation of rna metabolic process GO:0051252 391 0.019
Fly
central nervous system development GO:0007417 311 0.019
cellular process involved in reproduction in multicellular organism GO:0022412 35 0.019
regulation of cell growth GO:0001558 85 0.019
cellular response to abiotic stimulus GO:0071214 85 0.019
regulation of protein modification process GO:0031399 194 0.019
negative regulation of biosynthetic process GO:0009890 168 0.019
alternative mrna splicing via spliceosome GO:0000380 4 0.019
Fly
positive regulation of cellular component movement GO:0051272 102 0.019
enzyme linked receptor protein signaling pathway GO:0007167 116 0.019
regulation of sister chromatid segregation GO:0033045 1 0.019
negative regulation of cellular biosynthetic process GO:0031327 161 0.019
cellular macromolecule localization GO:0070727 122 0.019
peptidyl tyrosine phosphorylation GO:0018108 72 0.019
protein phosphorylation GO:0006468 345 0.018
axon development GO:0061564 96 0.018
carboxylic acid metabolic process GO:0019752 289 0.018
negative regulation of cell differentiation GO:0045596 99 0.018
regulation of neurogenesis GO:0050767 247 0.018
regulation of cellular response to stress GO:0080135 49 0.018
negative regulation of catalytic activity GO:0043086 103 0.018
regulation of dendrite development GO:0050773 59 0.018
cellular response to growth factor stimulus GO:0071363 162 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
response to cytokine GO:0034097 215 0.018
negative regulation of cell cycle phase transition GO:1901988 4 0.018
response to temperature stimulus GO:0009266 94 0.018
synaptic growth at neuromuscular junction GO:0051124 1 0.017
regulation of nervous system development GO:0051960 264 0.017
purine containing compound metabolic process GO:0072521 253 0.017
Yeast
regulation of immune response GO:0050776 55 0.017
response to uv GO:0009411 8 0.017
peptide transport GO:0015833 97 0.017
dna conformation change GO:0071103 10 0.017
protein maturation GO:0051604 68 0.017
positive regulation of hydrolase activity GO:0051345 86 0.016
positive regulation of intracellular signal transduction GO:1902533 138 0.016
cellular response to nutrient levels GO:0031669 60 0.016
signal transduction by phosphorylation GO:0023014 144 0.016
ion homeostasis GO:0050801 212 0.016
behavior GO:0007610 205 0.016
purine nucleotide metabolic process GO:0006163 229 0.016
Yeast
nitrogen compound transport GO:0071705 229 0.016
positive regulation of phosphorus metabolic process GO:0010562 262 0.016
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
cellular metal ion homeostasis GO:0006875 172 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
regulation of cell development GO:0060284 263 0.016
response to heat GO:0009408 60 0.016
calcium ion homeostasis GO:0055074 162 0.016
gliogenesis GO:0042063 93 0.016
cellular cation homeostasis GO:0030003 180 0.016
metal ion transport GO:0030001 289 0.016
ribonucleotide catabolic process GO:0009261 136 0.016
Yeast
protein localization to chromosome centromeric region GO:0071459 1 0.016
positive regulation of immune system process GO:0002684 90 0.015
epithelial cell differentiation GO:0030855 71 0.015
cytokine production GO:0001816 61 0.015
regeneration GO:0031099 163 0.015
positive regulation of cell development GO:0010720 176 0.015
ras protein signal transduction GO:0007265 29 0.015
synaptic transmission GO:0007268 235 0.015
response to inorganic substance GO:0010035 377 0.015
organelle localization GO:0051640 55 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
single organism biosynthetic process GO:0044711 342 0.015
nucleoside triphosphate catabolic process GO:0009143 123 0.015
Yeast
mitotic cell cycle GO:0000278 49 0.015
negative regulation of rna biosynthetic process GO:1902679 118 0.015
regulation of cytoskeleton organization GO:0051493 49 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.015
multicellular organism growth GO:0035264 1 0.014
cellular ion homeostasis GO:0006873 184 0.014
maintenance of location GO:0051235 17 0.014
regulation of mapk cascade GO:0043408 116 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
positive regulation of neurogenesis GO:0050769 165 0.014
purine nucleoside triphosphate catabolic process GO:0009146 122 0.014
Yeast
purine nucleotide catabolic process GO:0006195 136 0.014
Yeast
nucleoside catabolic process GO:0009164 126 0.014
Yeast
chromatin organization GO:0006325 34 0.014
developmental growth GO:0048589 100 0.014
localization of cell GO:0051674 202 0.013
positive regulation of protein modification process GO:0031401 142 0.013
microtubule based process GO:0007017 36 0.013
jak stat cascade GO:0007259 26 0.013
intracellular transport GO:0046907 185 0.013
organophosphate metabolic process GO:0019637 370 0.013
Yeast
purine ribonucleotide metabolic process GO:0009150 227 0.013
Yeast
regulation of defense response GO:0031347 68 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
hemidesmosome assembly GO:0031581 1 0.013
organ morphogenesis GO:0009887 75 0.013
immune response GO:0006955 104 0.013
regulation of smooth muscle cell proliferation GO:0048660 75 0.013
cellular protein localization GO:0034613 122 0.013
positive regulation of neurotransmitter secretion GO:0001956 9 0.013
protein localization to organelle GO:0033365 57 0.012
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 2 0.012
syncytium formation by plasma membrane fusion GO:0000768 3 0.012
neurotransmitter transport GO:0006836 42 0.012
embryonic axis specification GO:0000578 1 0.012
positive regulation of cell motility GO:2000147 97 0.012
response to amino acid GO:0043200 75 0.012
response to metal ion GO:0010038 253 0.012
positive regulation of transcription dna templated GO:0045893 197 0.012
microtubule cytoskeleton organization GO:0000226 25 0.012
positive regulation of behavior GO:0048520 38 0.012
dna recombination GO:0006310 3 0.012
purine nucleoside triphosphate metabolic process GO:0009144 141 0.012
Yeast
ribonucleotide metabolic process GO:0009259 231 0.012
Yeast
digestive tract development GO:0048565 39 0.012
oxoacid metabolic process GO:0043436 290 0.012
regulation of peptide hormone secretion GO:0090276 80 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.012
Yeast
nucleoside phosphate catabolic process GO:1901292 140 0.012
Yeast
negative regulation of signal transduction GO:0009968 83 0.012
chemosensory behavior GO:0007635 2 0.011
chromosome organization GO:0051276 36 0.011
cell cycle checkpoint GO:0000075 2 0.011
axis specification GO:0009798 4 0.011
rho protein signal transduction GO:0007266 11 0.011
single organism behavior GO:0044708 130 0.011
reproductive system development GO:0061458 128 0.011
rna localization GO:0006403 4 0.011
regulation of transcription dna templated GO:0006355 374 0.011
regulation of cell cycle g2 m phase transition GO:1902749 4 0.011
dendrite development GO:0016358 72 0.011
regulation of growth GO:0040008 105 0.011
regulation of dna metabolic process GO:0051052 60 0.011
ion transmembrane transport GO:0034220 365 0.011
blood vessel morphogenesis GO:0048514 58 0.011
organic anion transport GO:0015711 132 0.011
male sex differentiation GO:0046661 64 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
response to activity GO:0014823 73 0.011
rna processing GO:0006396 22 0.011
Fly
regulation of cell adhesion GO:0030155 52 0.011
dna integrity checkpoint GO:0031570 2 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
Yeast
female pregnancy GO:0007565 122 0.011
regulation of ion homeostasis GO:2000021 63 0.011
mrna metabolic process GO:0016071 20 0.011
Fly
cellular calcium ion homeostasis GO:0006874 160 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.011
negative regulation of protein processing GO:0010955 47 0.011
olfactory behavior GO:0042048 2 0.011
cellular response to lipid GO:0071396 201 0.011
regulation of cell projection organization GO:0031344 175 0.010
ribonucleoside metabolic process GO:0009119 174 0.010
Yeast
regulation of vesicle mediated transport GO:0060627 81 0.010
inorganic ion transmembrane transport GO:0098660 229 0.010
female sex differentiation GO:0046660 59 0.010
regulation of organelle organization GO:0033043 80 0.010
sensory organ development GO:0007423 74 0.010
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 1 0.010
regulation of vasculature development GO:1901342 44 0.010
myoblast fusion GO:0007520 2 0.010
positive regulation of signaling GO:0023056 270 0.010
chemotaxis GO:0006935 66 0.010
positive regulation of cell communication GO:0010647 271 0.010
regulation of protein processing GO:0070613 50 0.010
single organism cellular localization GO:1902580 102 0.010
single organism carbohydrate metabolic process GO:0044723 118 0.010
purine containing compound catabolic process GO:0072523 138 0.010
Yeast

Ddx46 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.061
muscular disease DOID:0080000 0 0.061
myopathy DOID:423 0 0.061
muscle tissue disease DOID:66 0 0.061
musculoskeletal system disease DOID:17 0 0.061
muscular dystrophy DOID:9884 0 0.061
central nervous system disease DOID:331 0 0.012
nervous system disease DOID:863 0 0.012