Rattus norvegicus

0 known processes

Dhdpsl

dihydrodipicolinate synthase-like, mitochondrial

(Aliases: Npl2,RGD1310475)

Dhdpsl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to purine containing compound GO:0014074 126 0.297
neuron projection development GO:0031175 273 0.253
positive regulation of programmed cell death GO:0043068 157 0.206
response to camp GO:0051591 91 0.204
carboxylic acid metabolic process GO:0019752 289 0.173
carboxylic acid biosynthetic process GO:0046394 83 0.162
oxoacid metabolic process GO:0043436 290 0.150
regulation of multicellular organismal development GO:2000026 376 0.140
organic acid biosynthetic process GO:0016053 83 0.137
response to hexose GO:0009746 144 0.135
negative regulation of pancreatic stellate cell proliferation GO:2000230 1 0.134
gland development GO:0048732 155 0.130
regulation of programmed cell death GO:0043067 341 0.128
positive regulation of cell death GO:0010942 184 0.121
transcription dna templated GO:0006351 377 0.114
transcription from rna polymerase ii promoter GO:0006366 252 0.113
response to nutrient GO:0007584 248 0.111
cell activation GO:0001775 97 0.109
regulation of cellular ketone metabolic process GO:0010565 27 0.105
programmed cell death GO:0012501 392 0.105
positive regulation of apoptotic process GO:0043065 154 0.100
macromolecular complex assembly GO:0065003 273 0.093
cell projection organization GO:0030030 302 0.092
vitamin d receptor signaling pathway GO:0070561 1 0.091
cellular component assembly GO:0022607 360 0.090
response to carbohydrate GO:0009743 183 0.089
regulation of neurogenesis GO:0050767 247 0.087
single organism biosynthetic process GO:0044711 342 0.084
response to metal ion GO:0010038 253 0.082
positive regulation of biosynthetic process GO:0009891 319 0.080
negative regulation of multicellular organismal process GO:0051241 203 0.079
regulation of protein phosphorylation GO:0001932 183 0.077
neuron differentiation GO:0030182 368 0.076
negative regulation of transcription dna templated GO:0045892 116 0.074
catabolic process GO:0009056 351 0.074
glutathione transport GO:0034635 2 0.073
apoptotic process GO:0006915 381 0.072
positive regulation of phagocytosis engulfment GO:0060100 4 0.072
response to cytokine GO:0034097 215 0.070
protein complex assembly GO:0006461 263 0.070
response to monosaccharide GO:0034284 159 0.067
response to organophosphorus GO:0046683 102 0.065
rna metabolic process GO:0016070 406 0.063
immune system process GO:0002376 204 0.062
neuron development GO:0048666 286 0.061
regulation of phagocytosis engulfment GO:0060099 4 0.061
organic acid metabolic process GO:0006082 292 0.059
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.059
cellular amino acid metabolic process GO:0006520 107 0.058
response to interleukin 1 GO:0070555 55 0.058
negative regulation of rna metabolic process GO:0051253 123 0.057
regulation of neuron projection development GO:0010975 161 0.057
protein complex subunit organization GO:0071822 302 0.056
response to glucose GO:0009749 136 0.056
reproductive structure development GO:0048608 128 0.055
response to reactive oxygen species GO:0000302 120 0.054
regulation of rna biosynthetic process GO:2001141 381 0.054
response to oxidative stress GO:0006979 186 0.054
central nervous system development GO:0007417 311 0.053
protein complex biogenesis GO:0070271 263 0.053
positive regulation of multicellular organismal process GO:0051240 387 0.053
vitamin a metabolic process GO:0006776 2 0.053
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.052
regulation of cellular protein metabolic process GO:0032268 267 0.052
regulation of rna metabolic process GO:0051252 391 0.051
regulation of cell development GO:0060284 263 0.051
pancreatic stellate cell proliferation GO:0072343 2 0.051
negative regulation of cellular metabolic process GO:0031324 281 0.050
monocarboxylic acid metabolic process GO:0032787 152 0.050
response to biotic stimulus GO:0009607 226 0.050
rna biosynthetic process GO:0032774 380 0.050
developmental process involved in reproduction GO:0003006 159 0.049
regulation of apoptotic process GO:0042981 335 0.048
response to nutrient levels GO:0031667 370 0.048
regulation of endocytosis GO:0030100 42 0.047
cellular component movement GO:0006928 248 0.047
regulation of nervous system development GO:0051960 264 0.046
axon development GO:0061564 96 0.046
negative regulation of cell proliferation GO:0008285 119 0.046
head development GO:0060322 247 0.046
negative regulation of response to stimulus GO:0048585 155 0.046
response to wounding GO:0009611 254 0.045
negative regulation of macromolecule metabolic process GO:0010605 260 0.044
response to retinoic acid GO:0032526 63 0.044
reproductive system development GO:0061458 128 0.044
negative regulation of metabolic process GO:0009892 331 0.044
regulation of cellular amino acid metabolic process GO:0006521 2 0.043
response to estrogen GO:0043627 232 0.043
cellular response to oxygen containing compound GO:1901701 386 0.042
regulation of cell differentiation GO:0045595 320 0.041
carbohydrate metabolic process GO:0005975 130 0.041
nucleic acid templated transcription GO:0097659 379 0.041
cellular response to cytokine stimulus GO:0071345 127 0.041
organic substance catabolic process GO:1901575 316 0.040
regulation of molecular function GO:0065009 398 0.039
protein oligomerization GO:0051259 191 0.039
regeneration GO:0031099 163 0.039
reproductive process GO:0022414 372 0.039
locomotion GO:0040011 237 0.038
positive regulation of rna metabolic process GO:0051254 203 0.038
response to peptide GO:1901652 292 0.038
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.038
placenta development GO:0001890 22 0.038
nucleoside phosphate metabolic process GO:0006753 283 0.037
regulation of catalytic activity GO:0050790 304 0.037
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.037
regulation of nucleic acid templated transcription GO:1903506 380 0.036
positive regulation of cellular component organization GO:0051130 200 0.036
cellular ketone metabolic process GO:0042180 51 0.036
multi multicellular organism process GO:0044706 138 0.036
regulation of protein metabolic process GO:0051246 289 0.035
regulation of neuron differentiation GO:0045664 208 0.035
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.035
tissue development GO:0009888 252 0.035
negative regulation of gene expression GO:0010629 199 0.034
mrna transcription GO:0009299 2 0.034
vesicle mediated transport GO:0016192 181 0.034
reproduction GO:0000003 245 0.033
regulation of cellular amine metabolic process GO:0033238 8 0.033
female pregnancy GO:0007565 122 0.033
positive regulation of protein phosphorylation GO:0001934 135 0.032
organelle organization GO:0006996 266 0.032
neuron projection morphogenesis GO:0048812 122 0.032
positive regulation of transcription dna templated GO:0045893 197 0.032
response to acid chemical GO:0001101 222 0.032
regulation of pancreatic stellate cell proliferation GO:2000229 2 0.032
cellular response to stress GO:0033554 269 0.031
single organism carbohydrate metabolic process GO:0044723 118 0.031
negative regulation of nucleic acid templated transcription GO:1903507 117 0.031
multicellular organism reproduction GO:0032504 233 0.031
negative regulation of cellular protein metabolic process GO:0032269 106 0.031
hexose metabolic process GO:0019318 58 0.031
response to hypoxia GO:0001666 231 0.030
regulation of cell proliferation GO:0042127 359 0.030
ribonucleoside metabolic process GO:0009119 174 0.030
response to metformin GO:1901558 1 0.030
regulation of cell projection organization GO:0031344 175 0.030
regulation of response to wounding GO:1903034 69 0.030
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.029
protein phosphorylation GO:0006468 345 0.029
regulation of cellular component organization GO:0051128 368 0.029
regulation of protein modification process GO:0031399 194 0.029
regulation of signal transduction GO:0009966 318 0.029
fatty acid metabolic process GO:0006631 99 0.029
cellular response to hormone stimulus GO:0032870 247 0.029
axonogenesis GO:0007409 71 0.029
response to estradiol GO:0032355 164 0.028
behavior GO:0007610 205 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.028
negative regulation of rna biosynthetic process GO:1902679 118 0.028
response to bacterium GO:0009617 200 0.028
response to external biotic stimulus GO:0043207 221 0.027
cellular component morphogenesis GO:0032989 155 0.027
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.027
proteolysis GO:0006508 175 0.027
macromolecular complex subunit organization GO:0043933 339 0.027
positive regulation of cell communication GO:0010647 271 0.027
cellular amine metabolic process GO:0044106 38 0.027
cellular response to interleukin 1 GO:0071347 37 0.026
positive regulation of nucleic acid templated transcription GO:1903508 197 0.026
dna metabolic process GO:0006259 96 0.026
organophosphate metabolic process GO:0019637 370 0.026
response to temperature stimulus GO:0009266 94 0.026
cellular component biogenesis GO:0044085 368 0.025
regulation of defense response GO:0031347 68 0.025
organonitrogen compound biosynthetic process GO:1901566 167 0.025
nitrogen compound transport GO:0071705 229 0.025
response to extracellular stimulus GO:0009991 380 0.025
limb morphogenesis GO:0035108 4 0.025
cell morphogenesis involved in differentiation GO:0000904 119 0.025
response to other organism GO:0051707 220 0.025
bmp signaling pathway GO:0030509 4 0.024
negative regulation of transcription regulatory region dna binding GO:2000678 2 0.024
response to transition metal nanoparticle GO:1990267 122 0.024
cell part morphogenesis GO:0032990 123 0.023
regulation of body fluid levels GO:0050878 90 0.023
response to osmotic stress GO:0006970 42 0.023
response to vitamin a GO:0033189 36 0.023
regulation of transcription dna templated GO:0006355 374 0.023
response to molecule of bacterial origin GO:0002237 194 0.023
positive regulation of gene expression GO:0010628 244 0.023
monocarboxylic acid biosynthetic process GO:0072330 48 0.023
organophosphate biosynthetic process GO:0090407 143 0.022
positive regulation of neuron projection development GO:0010976 99 0.022
negative regulation of developmental process GO:0051093 125 0.022
protein homooligomerization GO:0051260 91 0.022
regulation of response to stress GO:0080134 126 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
positive regulation of nervous system development GO:0051962 178 0.021
brain development GO:0007420 247 0.021
cell morphogenesis GO:0000902 142 0.021
negative regulation of signaling GO:0023057 157 0.021
positive regulation of cell development GO:0010720 176 0.021
response to decreased oxygen levels GO:0036293 237 0.020
cardiac chamber development GO:0003205 1 0.020
negative regulation of protein metabolic process GO:0051248 114 0.020
localization of cell GO:0051674 202 0.020
oxidation reduction process GO:0055114 304 0.020
regulation of transcription regulatory region dna binding GO:2000677 4 0.020
amine metabolic process GO:0009308 38 0.020
cellular response to organonitrogen compound GO:0071417 197 0.020
regulation of tube size GO:0035150 89 0.020
negative regulation of innate immune response GO:0045824 4 0.020
regulation of anatomical structure size GO:0090066 135 0.019
multi organism reproductive process GO:0044703 262 0.019
reactive oxygen species metabolic process GO:0072593 37 0.019
cellular catabolic process GO:0044248 295 0.019
anion transport GO:0006820 178 0.019
negative regulation of collagen biosynthetic process GO:0032966 4 0.019
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.019
nucleotide catabolic process GO:0009166 139 0.019
regulation of telomerase activity GO:0051972 2 0.019
positive regulation of signaling GO:0023056 270 0.019
endocrine system development GO:0035270 30 0.019
ribonucleotide metabolic process GO:0009259 231 0.019
circadian behavior GO:0048512 24 0.019
antibiotic transport GO:0042891 2 0.019
lipid metabolic process GO:0006629 283 0.019
response to vitamin GO:0033273 131 0.019
monosaccharide metabolic process GO:0005996 61 0.019
appendage morphogenesis GO:0035107 4 0.019
single organism carbohydrate catabolic process GO:0044724 40 0.018
response to lipopolysaccharide GO:0032496 191 0.018
negative regulation of catalytic activity GO:0043086 103 0.018
cell cycle checkpoint GO:0000075 2 0.018
cellular response to camp GO:0071320 26 0.018
rhythmic behavior GO:0007622 24 0.018
positive regulation of transport GO:0051050 245 0.018
regulation of fat cell differentiation GO:0045598 3 0.018
epithelial cell differentiation GO:0030855 71 0.018
nucleobase containing small molecule metabolic process GO:0055086 316 0.018
cellular amide metabolic process GO:0043603 44 0.018
reactive nitrogen species metabolic process GO:2001057 1 0.017
cellular response to vitamin e GO:0071306 3 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.017
intracellular signal transduction GO:0035556 314 0.017
positive regulation of endocytosis GO:0045807 28 0.017
carboxylic acid transport GO:0046942 115 0.017
regulation of cell migration GO:0030334 128 0.017
chemotaxis GO:0006935 66 0.017
peptide transport GO:0015833 97 0.017
cellular response to abiotic stimulus GO:0071214 85 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
positive regulation of epidermis development GO:0045684 1 0.016
cellular response to inorganic substance GO:0071241 65 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
microvillus assembly GO:0030033 2 0.016
leukocyte activation GO:0045321 76 0.016
cellular lipid metabolic process GO:0044255 208 0.016
positive regulation of cellular biosynthetic process GO:0031328 295 0.016
regulation of neuron death GO:1901214 115 0.016
sleep GO:0030431 30 0.016
homeostatic process GO:0042592 331 0.016
single organism catabolic process GO:0044712 283 0.016
nucleobase containing compound catabolic process GO:0034655 152 0.016
defense response to gram positive bacterium GO:0050830 2 0.016
negative regulation of viral process GO:0048525 4 0.016
cell migration GO:0016477 197 0.016
response to corticosteroid GO:0031960 235 0.015
regulation of phosphate metabolic process GO:0019220 349 0.015
protein maturation GO:0051604 68 0.015
metal ion transport GO:0030001 289 0.015
single organism reproductive process GO:0044702 297 0.015
response to activity GO:0014823 73 0.015
response to molecule of fungal origin GO:0002238 3 0.015
anterior posterior pattern specification GO:0009952 1 0.015
sex differentiation GO:0007548 113 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
glycolytic process GO:0006096 17 0.014
negative regulation of cell differentiation GO:0045596 99 0.014
gonad development GO:0008406 104 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
lipid biosynthetic process GO:0008610 128 0.014
circadian sleep wake cycle GO:0042745 23 0.014
single organism organelle organization GO:1902589 180 0.014
peptidyl amino acid modification GO:0018193 126 0.014
small molecule biosynthetic process GO:0044283 124 0.014
regulation of intracellular signal transduction GO:1902531 218 0.014
negative regulation of telomerase activity GO:0051974 1 0.014
endocytosis GO:0006897 84 0.014
cell projection morphogenesis GO:0048858 123 0.014
cellular response to endogenous stimulus GO:0071495 377 0.014
chromosome segregation GO:0007059 2 0.014
cellular homeostasis GO:0019725 252 0.014
cellular response to alcohol GO:0097306 87 0.014
purine nucleotide metabolic process GO:0006163 229 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
cell adhesion GO:0007155 110 0.013
response to oxygen levels GO:0070482 265 0.013
defense response GO:0006952 194 0.013
organic acid transport GO:0015849 116 0.013
axis specification GO:0009798 4 0.013
c21 steroid hormone biosynthetic process GO:0006700 10 0.013
olfactory behavior GO:0042048 2 0.013
positive regulation of signal transduction GO:0009967 175 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
cellular response to organic cyclic compound GO:0071407 202 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
regulation of locomotion GO:0040012 148 0.013
peptidyl tyrosine modification GO:0018212 72 0.013
alpha amino acid metabolic process GO:1901605 71 0.013
cell cell signaling GO:0007267 335 0.013
organic hydroxy compound transport GO:0015850 77 0.013
regulation of transferase activity GO:0051338 123 0.013
regulation of ion transport GO:0043269 245 0.013
response to mechanical stimulus GO:0009612 134 0.013
isoprenoid metabolic process GO:0006720 45 0.013
nucleoside triphosphate metabolic process GO:0009141 144 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.012
response to axon injury GO:0048678 59 0.012
negative regulation of cell communication GO:0010648 158 0.012
response to peptide hormone GO:0043434 278 0.012
fibroblast proliferation GO:0048144 22 0.012
cellular response to external stimulus GO:0071496 118 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
circadian rhythm GO:0007623 88 0.012
carbohydrate catabolic process GO:0016052 40 0.012
embryonic limb morphogenesis GO:0030326 4 0.012
regulation of lipid biosynthetic process GO:0046890 38 0.012
neuron death GO:0070997 127 0.012
microtubule cytoskeleton organization GO:0000226 25 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
lipid storage GO:0019915 1 0.012
negative regulation of molecular function GO:0044092 133 0.012
response to testosterone GO:0033574 55 0.012
actin filament depolymerization GO:0030042 3 0.012
cell growth GO:0016049 104 0.012
embryonic pattern specification GO:0009880 1 0.012
positive regulation of neuron death GO:1901216 43 0.012
carbohydrate derivative metabolic process GO:1901135 346 0.012
cellular response to reactive oxygen species GO:0034614 55 0.012
negative regulation of nuclear division GO:0051784 1 0.012
cellular response to lipid GO:0071396 201 0.012
tube development GO:0035295 89 0.012
defense response to gram negative bacterium GO:0050829 3 0.011
heart morphogenesis GO:0003007 3 0.011
response to radiation GO:0009314 137 0.011
excretion GO:0007588 24 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
posttranscriptional regulation of gene expression GO:0010608 37 0.011
positive regulation of long term synaptic potentiation GO:1900273 4 0.011
heterocycle catabolic process GO:0046700 167 0.011
response to hydrogen peroxide GO:0042542 89 0.011
regulation of secretion GO:0051046 224 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
embryonic axis specification GO:0000578 1 0.011
multicellular organismal signaling GO:0035637 44 0.011
ribonucleoside monophosphate metabolic process GO:0009161 88 0.011
cardiac muscle tissue morphogenesis GO:0055008 1 0.011
cellular response to extracellular stimulus GO:0031668 73 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
regulation of phosphorus metabolic process GO:0051174 349 0.011
vasodilation GO:0042311 44 0.011
chemosensory behavior GO:0007635 2 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
regulation of blood vessel size GO:0050880 89 0.011
negative regulation of secretion GO:0051048 82 0.011
response to vitamin e GO:0033197 24 0.011
centrosome organization GO:0051297 1 0.011
negative regulation of cell death GO:0060548 229 0.011
retinoid metabolic process GO:0001523 24 0.010
amide transport GO:0042886 105 0.010
meiotic cell cycle process GO:1903046 3 0.010
neuromuscular process GO:0050905 2 0.010
neuron projection regeneration GO:0031102 35 0.010
wound healing GO:0042060 122 0.010
cellular cation homeostasis GO:0030003 180 0.010
fertilization GO:0009566 3 0.010
purine nucleoside monophosphate metabolic process GO:0009126 84 0.010
programmed necrotic cell death GO:0097300 2 0.010
regulation of kinase activity GO:0043549 117 0.010
cellular amino acid biosynthetic process GO:0008652 32 0.010
regulation of cell growth GO:0001558 85 0.010
nucleoside monophosphate metabolic process GO:0009123 93 0.010
aging GO:0007568 241 0.010
heart development GO:0007507 72 0.010
circulatory system development GO:0072359 134 0.010
cellular chemical homeostasis GO:0055082 247 0.010
inflammatory response GO:0006954 150 0.010
spindle organization GO:0007051 2 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010
regulation of reactive oxygen species metabolic process GO:2000377 26 0.010
response to ketone GO:1901654 182 0.010

Dhdpsl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.043
inherited metabolic disorder DOID:655 0 0.043
disease of cellular proliferation DOID:14566 0 0.023
disease of anatomical entity DOID:7 0 0.020
bone disease DOID:0080001 0 0.020
musculoskeletal system disease DOID:17 0 0.020
connective tissue disease DOID:65 0 0.020
organ system cancer DOID:0050686 0 0.015
cancer DOID:162 0 0.015
cardiovascular system disease DOID:1287 0 0.013
heart disease DOID:114 0 0.013
congenital heart disease DOID:1682 0 0.013
heart septal defect DOID:1681 0 0.013
nervous system disease DOID:863 0 0.011