Rattus norvegicus

0 known processes

Diras1

DIRAS family, GTP-binding RAS-like 1

Diras1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
single organism biosynthetic process GO:0044711 342 0.103
regulation of cellular ketone metabolic process GO:0010565 27 0.099
development of primary sexual characteristics GO:0045137 107 0.095
cation transport GO:0006812 382 0.091
regulation of molecular function GO:0065009 398 0.089
Rat
homeostatic process GO:0042592 331 0.085
organic acid metabolic process GO:0006082 292 0.080
positive regulation of signaling GO:0023056 270 0.080
Rat
secretion by cell GO:0032940 248 0.071
oxoacid metabolic process GO:0043436 290 0.071
ion transmembrane transport GO:0034220 365 0.069
cellular amino acid metabolic process GO:0006520 107 0.066
lipid metabolic process GO:0006629 283 0.066
rna metabolic process GO:0016070 406 0.063
cellular lipid metabolic process GO:0044255 208 0.062
response to metal ion GO:0010038 253 0.061
carboxylic acid metabolic process GO:0019752 289 0.059
response to acid chemical GO:0001101 222 0.058
head development GO:0060322 247 0.058
protein phosphorylation GO:0006468 345 0.057
Rat
regulation of rna metabolic process GO:0051252 391 0.055
gonad development GO:0008406 104 0.055
positive regulation of multicellular organismal process GO:0051240 387 0.055
Rat
cation transmembrane transport GO:0098655 263 0.054
cellular ketone metabolic process GO:0042180 51 0.053
inorganic cation transmembrane transport GO:0098662 202 0.053
regulation of cellular amino acid metabolic process GO:0006521 2 0.052
positive regulation of secretion GO:0051047 140 0.052
rna biosynthetic process GO:0032774 380 0.050
negative regulation of cellular metabolic process GO:0031324 281 0.049
sex differentiation GO:0007548 113 0.048
regulation of phosphate metabolic process GO:0019220 349 0.047
Rat
response to inorganic substance GO:0010035 377 0.047
regulation of cellular amine metabolic process GO:0033238 8 0.046
regulation of protein phosphorylation GO:0001932 183 0.046
Rat
negative regulation of metabolic process GO:0009892 331 0.046
regulation of nucleic acid templated transcription GO:1903506 380 0.045
positive regulation of phosphorus metabolic process GO:0010562 262 0.045
Rat
response to alkaloid GO:0043279 132 0.045
neuron differentiation GO:0030182 368 0.044
Rat
response to biotic stimulus GO:0009607 226 0.043
cellular response to oxygen containing compound GO:1901701 386 0.042
positive regulation of protein modification process GO:0031401 142 0.041
Rat
apoptotic process GO:0006915 381 0.041
inorganic ion transmembrane transport GO:0098660 229 0.040
positive regulation of protein metabolic process GO:0051247 178 0.040
Rat
regulation of protein metabolic process GO:0051246 289 0.040
Rat
cell projection organization GO:0030030 302 0.040
Rat
vesicle mediated transport GO:0016192 181 0.039
regulation of intracellular signal transduction GO:1902531 218 0.039
Rat
heart morphogenesis GO:0003007 3 0.038
response to other organism GO:0051707 220 0.037
exocytosis GO:0006887 60 0.037
cellular amine metabolic process GO:0044106 38 0.037
regulation of phosphorus metabolic process GO:0051174 349 0.036
Rat
nucleic acid templated transcription GO:0097659 379 0.036
regulation of catalytic activity GO:0050790 304 0.036
Rat
regulation of secretion by cell GO:1903530 208 0.036
organ morphogenesis GO:0009887 75 0.036
regulation of cellular component organization GO:0051128 368 0.035
Rat
positive regulation of cellular amine metabolic process GO:0033240 3 0.035
neuron projection development GO:0031175 273 0.034
Rat
response to corticosteroid GO:0031960 235 0.034
cellular component biogenesis GO:0044085 368 0.034
regulation of neurogenesis GO:0050767 247 0.033
Rat
negative regulation of programmed cell death GO:0043069 183 0.033
central nervous system development GO:0007417 311 0.033
response to glucocorticoid GO:0051384 223 0.033
mesoderm development GO:0007498 2 0.033
transmission of nerve impulse GO:0019226 42 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.032
Rat
positive regulation of gene expression GO:0010628 244 0.032
positive regulation of developmental process GO:0051094 283 0.031
Rat
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.031
positive regulation of phosphorylation GO:0042327 177 0.031
Rat
regulation of transcription dna templated GO:0006355 374 0.031
nucleobase containing small molecule metabolic process GO:0055086 316 0.030
Human Rat
transmembrane transport GO:0055085 412 0.030
positive regulation of cellular biosynthetic process GO:0031328 295 0.029
positive regulation of calcium ion transport GO:0051928 36 0.029
negative regulation of biosynthetic process GO:0009890 168 0.029
transcription dna templated GO:0006351 377 0.029
positive regulation of transport GO:0051050 245 0.028
sodium ion transport GO:0006814 82 0.028
brain development GO:0007420 247 0.028
neuronal action potential GO:0019228 35 0.028
response to carbohydrate GO:0009743 183 0.028
ensheathment of neurons GO:0007272 40 0.028
regulation of rna biosynthetic process GO:2001141 381 0.028
positive regulation of cell proliferation GO:0008284 249 0.028
amine metabolic process GO:0009308 38 0.027
regulation of system process GO:0044057 208 0.027
dephosphorylation GO:0016311 98 0.026
carbohydrate derivative metabolic process GO:1901135 346 0.026
Human Rat
lipid biosynthetic process GO:0008610 128 0.026
positive regulation of protein phosphorylation GO:0001934 135 0.026
Rat
multicellular organism reproduction GO:0032504 233 0.026
behavior GO:0007610 205 0.026
response to monosaccharide GO:0034284 159 0.025
programmed cell death GO:0012501 392 0.025
regulation of protein modification process GO:0031399 194 0.025
Rat
signal release GO:0023061 145 0.025
regulation of cell differentiation GO:0045595 320 0.025
Rat
cellular response to nitrogen compound GO:1901699 210 0.025
regulation of organelle organization GO:0033043 80 0.024
regulation of cellular localization GO:0060341 263 0.024
regulation of secretion GO:0051046 224 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.024
Rat
negative regulation of macromolecule metabolic process GO:0010605 260 0.023
reproductive process GO:0022414 372 0.023
axon development GO:0061564 96 0.023
regulation of cellular protein metabolic process GO:0032268 267 0.023
Rat
reproductive system development GO:0061458 128 0.023
regulation of protein kinase activity GO:0045859 105 0.023
Rat
intracellular transport GO:0046907 185 0.023
negative regulation of phosphorus metabolic process GO:0010563 80 0.023
positive regulation of response to stimulus GO:0048584 285 0.023
Rat
reproduction GO:0000003 245 0.022
multicellular organismal reproductive process GO:0048609 233 0.022
negative regulation of protein metabolic process GO:0051248 114 0.022
purine containing compound metabolic process GO:0072521 253 0.022
Human Rat
regulation of multicellular organismal development GO:2000026 376 0.022
Rat
locomotion GO:0040011 237 0.022
positive regulation of biosynthetic process GO:0009891 319 0.022
positive regulation of phosphate metabolic process GO:0045937 262 0.022
Rat
negative regulation of cellular protein metabolic process GO:0032269 106 0.022
spermatogenesis GO:0007283 99 0.021
negative regulation of apoptotic process GO:0043066 181 0.021
negative regulation of cell death GO:0060548 229 0.021
negative regulation of molecular function GO:0044092 133 0.020
alcohol metabolic process GO:0006066 77 0.020
regulation of neuron differentiation GO:0045664 208 0.020
Rat
sodium ion transmembrane transport GO:0035725 67 0.020
secretion GO:0046903 307 0.020
organophosphate metabolic process GO:0019637 370 0.019
Human Rat
positive regulation of cellular protein metabolic process GO:0032270 167 0.019
Rat
proteolysis GO:0006508 175 0.019
cell type specific apoptotic process GO:0097285 134 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
Rat
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
anatomical structure morphogenesis GO:0009653 298 0.018
hematopoietic progenitor cell differentiation GO:0002244 2 0.018
positive regulation of molecular function GO:0044093 230 0.018
Rat
reproductive structure development GO:0048608 128 0.018
enzyme linked receptor protein signaling pathway GO:0007167 116 0.018
response to extracellular stimulus GO:0009991 380 0.018
carboxylic acid transport GO:0046942 115 0.018
ras protein signal transduction GO:0007265 29 0.018
regulation of homotypic cell cell adhesion GO:0034110 4 0.017
carbohydrate metabolic process GO:0005975 130 0.017
regulation of programmed cell death GO:0043067 341 0.017
divalent inorganic cation transport GO:0072511 134 0.017
amino acid transport GO:0006865 70 0.017
tube development GO:0035295 89 0.017
response to transition metal nanoparticle GO:1990267 122 0.017
regulation of vesicle mediated transport GO:0060627 81 0.017
nitrogen compound transport GO:0071705 229 0.017
negative regulation of gene expression GO:0010629 199 0.017
negative regulation of transport GO:0051051 136 0.017
negative regulation of cell communication GO:0010648 158 0.017
positive regulation of intracellular signal transduction GO:1902533 138 0.017
Rat
single organism carbohydrate metabolic process GO:0044723 118 0.017
regulation of locomotion GO:0040012 148 0.017
regulation of ion transport GO:0043269 245 0.017
regulation of immune system process GO:0002682 123 0.017
male gonad development GO:0008584 59 0.016
regulation of kinase activity GO:0043549 117 0.016
Rat
heart development GO:0007507 72 0.016
response to testosterone GO:0033574 55 0.016
cation homeostasis GO:0055080 195 0.016
anatomical structure homeostasis GO:0060249 29 0.016
small molecule biosynthetic process GO:0044283 124 0.016
multi organism reproductive process GO:0044703 262 0.016
multicellular organismal homeostasis GO:0048871 49 0.016
cellular response to lipid GO:0071396 201 0.016
cellular response to organic cyclic compound GO:0071407 202 0.016
regulation of phosphorylation GO:0042325 248 0.016
Rat
gamete generation GO:0007276 124 0.016
male sex differentiation GO:0046661 64 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
Rat
localization of cell GO:0051674 202 0.015
male gamete generation GO:0048232 99 0.015
developmental process involved in reproduction GO:0003006 159 0.015
aging GO:0007568 241 0.015
circulatory system development GO:0072359 134 0.015
cardiovascular system development GO:0072358 134 0.015
sensory perception of pain GO:0019233 73 0.015
leukocyte activation GO:0045321 76 0.015
response to calcium ion GO:0051592 59 0.015
immune response GO:0006955 104 0.015
response to external biotic stimulus GO:0043207 221 0.015
positive regulation of cell projection organization GO:0031346 111 0.015
Rat
chemotaxis GO:0006935 66 0.015
protein complex subunit organization GO:0071822 302 0.015
response to lipopolysaccharide GO:0032496 191 0.014
cellular response to external stimulus GO:0071496 118 0.014
regulation of transferase activity GO:0051338 123 0.014
Rat
response to molecule of bacterial origin GO:0002237 194 0.014
cell motility GO:0048870 202 0.014
cytoplasmic transport GO:0016482 115 0.014
negative regulation of cell proliferation GO:0008285 119 0.014
cyclic nucleotide metabolic process GO:0009187 80 0.014
positive regulation of cell death GO:0010942 184 0.014
response to peptide hormone GO:0043434 278 0.014
cellular component movement GO:0006928 248 0.014
ovulation cycle process GO:0022602 50 0.014
regulation of hormone secretion GO:0046883 106 0.014
divalent metal ion transport GO:0070838 132 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
Rat
negative regulation of phosphate metabolic process GO:0045936 80 0.014
organelle organization GO:0006996 266 0.014
protein tetramerization GO:0051262 38 0.013
positive regulation of transferase activity GO:0051347 81 0.013
Rat
cellular chemical homeostasis GO:0055082 247 0.013
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.013
metal ion transport GO:0030001 289 0.013
regulation of nervous system development GO:0051960 264 0.013
Rat
cell morphogenesis involved in differentiation GO:0000904 119 0.013
female sex differentiation GO:0046660 59 0.013
organic anion transport GO:0015711 132 0.013
response to radiation GO:0009314 137 0.013
neurotransmitter transport GO:0006836 42 0.013
chromosome segregation GO:0007059 2 0.013
peptidyl amino acid modification GO:0018193 126 0.013
intestinal absorption GO:0050892 3 0.013
salivary gland development GO:0007431 3 0.013
multicellular organism growth GO:0035264 1 0.013
cellular response to organonitrogen compound GO:0071417 197 0.012
organic acid transport GO:0015849 116 0.012
carbohydrate homeostasis GO:0033500 75 0.012
defense response GO:0006952 194 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
phospholipid metabolic process GO:0006644 61 0.012
negative regulation of neuron differentiation GO:0045665 62 0.012
regulation of protein serine threonine kinase activity GO:0071900 64 0.012
response to cytokine GO:0034097 215 0.012
regulation of ion transmembrane transporter activity GO:0032412 48 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
organic hydroxy compound transport GO:0015850 77 0.012
endomembrane system organization GO:0010256 48 0.012
macromolecule localization GO:0033036 252 0.012
response to oxidative stress GO:0006979 186 0.012
positive regulation of cell migration GO:0030335 96 0.012
regulation of cell projection organization GO:0031344 175 0.012
Rat
negative regulation of secretion GO:0051048 82 0.012
vitamin d metabolic process GO:0042359 4 0.012
positive regulation of kinase activity GO:0033674 77 0.012
Rat
regulation of lipid metabolic process GO:0019216 68 0.012
positive regulation of protein kinase activity GO:0045860 73 0.012
Rat
lipid modification GO:0030258 52 0.012
neurological system process GO:0050877 219 0.012
cellular response to peptide GO:1901653 133 0.012
lipid transport GO:0006869 61 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
single organism intracellular transport GO:1902582 166 0.011
ribonucleotide biosynthetic process GO:0009260 85 0.011
response to glucose GO:0009749 136 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
cellular response to hormone stimulus GO:0032870 247 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
Rat
intracellular signal transduction GO:0035556 314 0.011
Rat
rhythmic process GO:0048511 156 0.011
development of primary male sexual characteristics GO:0046546 59 0.011
lipid localization GO:0010876 62 0.011
positive regulation of rna biosynthetic process GO:1902680 197 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
Rat
sensory perception GO:0007600 101 0.011
single organism cellular localization GO:1902580 102 0.011
regulation of peptide transport GO:0090087 87 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
Rat
eye development GO:0001654 50 0.011
nucleotide metabolic process GO:0009117 279 0.011
Human Rat
regulation of signal transduction GO:0009966 318 0.011
Rat
organic hydroxy compound biosynthetic process GO:1901617 51 0.011
positive regulation of immune system process GO:0002684 90 0.011
tissue development GO:0009888 252 0.011
eye morphogenesis GO:0048592 4 0.011
response to ketone GO:1901654 182 0.011
detection of stimulus GO:0051606 24 0.011
cellular homeostasis GO:0019725 252 0.010
neuron development GO:0048666 286 0.010
Rat
anatomical structure formation involved in morphogenesis GO:0048646 83 0.010
calcium ion transmembrane transport GO:0070588 70 0.010
amide transport GO:0042886 105 0.010
positive regulation of growth GO:0045927 55 0.010
single organism reproductive process GO:0044702 297 0.010
response to hexose GO:0009746 144 0.010
cellular response to acid chemical GO:0071229 75 0.010
regulation of apoptotic process GO:0042981 335 0.010
hormone secretion GO:0046879 115 0.010
carbohydrate derivative biosynthetic process GO:1901137 124 0.010

Diras1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.087
disease of anatomical entity DOID:7 0 0.087
nervous system disease DOID:863 0 0.087
eye and adnexa disease DOID:1492 0 0.071
retinal disease DOID:5679 0 0.036
eye disease DOID:5614 0 0.036
retinal degeneration DOID:8466 0 0.016
central nervous system disease DOID:331 0 0.011