Rattus norvegicus

35 known processes

Dlat

dihydrolipoamide S-acetyltransferase

Dlat biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
acetyl coa biosynthetic process from pyruvate GO:0006086 5 0.528
carboxylic acid metabolic process GO:0019752 289 0.510
energy derivation by oxidation of organic compounds GO:0015980 46 0.494
dicarboxylic acid metabolic process GO:0043648 42 0.330
monocarboxylic acid metabolic process GO:0032787 152 0.322
oxoacid metabolic process GO:0043436 290 0.322
cofactor biosynthetic process GO:0051188 28 0.313
pyruvate metabolic process GO:0006090 27 0.287
organophosphate metabolic process GO:0019637 370 0.274
acyl coa metabolic process GO:0006637 28 0.251
acetyl coa metabolic process GO:0006084 17 0.251
coenzyme metabolic process GO:0006732 86 0.215
oxidation reduction process GO:0055114 304 0.214
organic acid metabolic process GO:0006082 292 0.190
nucleobase containing small molecule metabolic process GO:0055086 316 0.186
cellular respiration GO:0045333 21 0.179
generation of precursor metabolites and energy GO:0006091 62 0.152
nucleotide metabolic process GO:0009117 279 0.141
nucleoside phosphate metabolic process GO:0006753 283 0.127
purine ribonucleotide metabolic process GO:0009150 227 0.122
purine nucleoside metabolic process GO:0042278 169 0.120
regulation of cell proliferation GO:0042127 359 0.113
cofactor metabolic process GO:0051186 95 0.111
purine nucleoside triphosphate metabolic process GO:0009144 141 0.110
hydrogen peroxide metabolic process GO:0042743 13 0.100
sulfur compound biosynthetic process GO:0044272 19 0.099
apoptotic process GO:0006915 381 0.094
ribonucleoside triphosphate metabolic process GO:0009199 141 0.094
purine nucleotide metabolic process GO:0006163 229 0.092
programmed cell death GO:0012501 392 0.088
ribonucleoside metabolic process GO:0009119 174 0.087
carbohydrate derivative metabolic process GO:1901135 346 0.075
ribose phosphate metabolic process GO:0019693 235 0.073
ribonucleotide metabolic process GO:0009259 231 0.073
organelle organization GO:0006996 266 0.072
reactive oxygen species metabolic process GO:0072593 37 0.072
apoptotic mitochondrial changes GO:0008637 10 0.066
response to extracellular stimulus GO:0009991 380 0.065
ion transmembrane transport GO:0034220 365 0.063
purine ribonucleoside metabolic process GO:0046128 168 0.061
organophosphate catabolic process GO:0046434 148 0.059
acyl coa biosynthetic process GO:0071616 7 0.058
single organism biosynthetic process GO:0044711 342 0.057
regulation of protein metabolic process GO:0051246 289 0.056
thioester biosynthetic process GO:0035384 7 0.053
response to oxygen levels GO:0070482 265 0.053
response to decreased oxygen levels GO:0036293 237 0.052
regulation of catalytic activity GO:0050790 304 0.052
regulation of apoptotic process GO:0042981 335 0.048
g protein coupled receptor signaling pathway GO:0007186 242 0.048
pyridine containing compound metabolic process GO:0072524 32 0.047
purine nucleoside monophosphate metabolic process GO:0009126 84 0.046
mitochondrion organization GO:0007005 35 0.045
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.042
nitrogen compound transport GO:0071705 229 0.042
transmembrane transport GO:0055085 412 0.041
response to acid chemical GO:0001101 222 0.040
regulation of hydrolase activity GO:0051336 143 0.039
macromolecular complex subunit organization GO:0043933 339 0.039
regulation of molecular function GO:0065009 398 0.038
nucleoside triphosphate metabolic process GO:0009141 144 0.037
dephosphorylation GO:0016311 98 0.037
glycosyl compound metabolic process GO:1901657 182 0.037
alpha amino acid metabolic process GO:1901605 71 0.037
response to inorganic substance GO:0010035 377 0.036
response to nutrient GO:0007584 248 0.034
organonitrogen compound catabolic process GO:1901565 179 0.034
response to hypoxia GO:0001666 231 0.034
thioester metabolic process GO:0035383 28 0.034
response to oxidative stress GO:0006979 186 0.034
positive regulation of programmed cell death GO:0043068 157 0.034
cellular response to stress GO:0033554 269 0.034
inorganic ion transmembrane transport GO:0098660 229 0.033
atp metabolic process GO:0046034 72 0.033
acetyl coa biosynthetic process GO:0006085 6 0.032
cell type specific apoptotic process GO:0097285 134 0.031
nicotinamide nucleotide metabolic process GO:0046496 28 0.030
positive regulation of cellular protein metabolic process GO:0032270 167 0.030
homeostatic process GO:0042592 331 0.030
response to bacterium GO:0009617 200 0.029
oxidative phosphorylation GO:0006119 4 0.029
positive regulation of developmental process GO:0051094 283 0.029
single organism catabolic process GO:0044712 283 0.029
sulfur compound metabolic process GO:0006790 70 0.028
rhythmic process GO:0048511 156 0.028
aging GO:0007568 241 0.028
nucleoside metabolic process GO:0009116 179 0.027
cellular response to endogenous stimulus GO:0071495 377 0.027
purine containing compound metabolic process GO:0072521 253 0.027
regulation of multicellular organismal development GO:2000026 376 0.027
cellular amino acid metabolic process GO:0006520 107 0.027
organic substance catabolic process GO:1901575 316 0.027
response to peptide hormone GO:0043434 278 0.027
oxidoreduction coenzyme metabolic process GO:0006733 31 0.026
regulation of anatomical structure morphogenesis GO:0022603 141 0.026
response to nutrient levels GO:0031667 370 0.026
carbohydrate derivative catabolic process GO:1901136 147 0.026
regulation of cell differentiation GO:0045595 320 0.026
rna metabolic process GO:0016070 406 0.026
negative regulation of apoptotic process GO:0043066 181 0.025
small gtpase mediated signal transduction GO:0007264 36 0.025
cellular homeostasis GO:0019725 252 0.025
positive regulation of response to stimulus GO:0048584 285 0.025
regulation of ion transport GO:0043269 245 0.024
regulation of gtpase activity GO:0043087 57 0.024
ras protein signal transduction GO:0007265 29 0.024
response to carbohydrate GO:0009743 183 0.024
cation transmembrane transport GO:0098655 263 0.024
atp synthesis coupled electron transport GO:0042773 2 0.024
regulation of programmed cell death GO:0043067 341 0.024
protein localization GO:0008104 191 0.023
purine nucleoside triphosphate catabolic process GO:0009146 122 0.023
regulation of cellular component organization GO:0051128 368 0.023
cellular nitrogen compound catabolic process GO:0044270 163 0.023
positive regulation of cell differentiation GO:0045597 217 0.023
positive regulation of protein metabolic process GO:0051247 178 0.022
response to peptide GO:1901652 292 0.022
single organism carbohydrate metabolic process GO:0044723 118 0.022
defense response GO:0006952 194 0.021
aromatic compound catabolic process GO:0019439 168 0.021
protein dephosphorylation GO:0006470 38 0.021
cardiac chamber development GO:0003205 1 0.021
heterocycle catabolic process GO:0046700 167 0.021
negative regulation of metabolic process GO:0009892 331 0.021
intracellular signal transduction GO:0035556 314 0.021
coenzyme biosynthetic process GO:0009108 22 0.021
response to toxic substance GO:0009636 133 0.020
single organism organelle organization GO:1902589 180 0.020
nucleocytoplasmic transport GO:0006913 48 0.020
regulation of purine nucleotide catabolic process GO:0033121 65 0.020
amine metabolic process GO:0009308 38 0.020
cellular response to oxygen containing compound GO:1901701 386 0.019
mitotic sister chromatid separation GO:0051306 1 0.019
negative regulation of macromolecule metabolic process GO:0010605 260 0.019
cellular amine metabolic process GO:0044106 38 0.019
organic cyclic compound catabolic process GO:1901361 175 0.019
chemical homeostasis GO:0048878 292 0.019
nucleobase containing compound catabolic process GO:0034655 152 0.019
positive regulation of cellular component organization GO:0051130 200 0.019
carbohydrate metabolic process GO:0005975 130 0.019
purine containing compound catabolic process GO:0072523 138 0.019
purine nucleoside catabolic process GO:0006152 124 0.019
regulation of cellular protein metabolic process GO:0032268 267 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.018
response to estrogen GO:0043627 232 0.018
regulation of cellular localization GO:0060341 263 0.018
regulation of cellular amino acid metabolic process GO:0006521 2 0.018
negative regulation of cell death GO:0060548 229 0.018
negative regulation of reactive oxygen species metabolic process GO:2000378 7 0.018
protein complex subunit organization GO:0071822 302 0.018
oxaloacetate metabolic process GO:0006107 6 0.017
regulation of purine nucleotide metabolic process GO:1900542 115 0.017
cellular catabolic process GO:0044248 295 0.017
proteolysis GO:0006508 175 0.017
negative regulation of signaling GO:0023057 157 0.017
negative regulation of cellular metabolic process GO:0031324 281 0.017
ribonucleoside triphosphate catabolic process GO:0009203 122 0.017
metaphase plate congression GO:0051310 1 0.016
neuron projection morphogenesis GO:0048812 122 0.016
catabolic process GO:0009056 351 0.016
peptide transport GO:0015833 97 0.016
regulation of neurogenesis GO:0050767 247 0.016
positive regulation of molecular function GO:0044093 230 0.016
negative regulation of developmental process GO:0051093 125 0.016
regulation of stem cell proliferation GO:0072091 14 0.016
nucleoside phosphate catabolic process GO:1901292 140 0.016
carbohydrate homeostasis GO:0033500 75 0.016
secretion GO:0046903 307 0.016
regulation of phosphate metabolic process GO:0019220 349 0.015
macromolecule localization GO:0033036 252 0.015
metal ion transport GO:0030001 289 0.015
regulation of secretion by cell GO:1903530 208 0.015
cellular response to organonitrogen compound GO:0071417 197 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
positive regulation of multicellular organismal process GO:0051240 387 0.015
metaphase anaphase transition of mitotic cell cycle GO:0007091 1 0.015
regulation of peptide transport GO:0090087 87 0.015
neuron differentiation GO:0030182 368 0.015
anion transport GO:0006820 178 0.015
response to monosaccharide GO:0034284 159 0.015
response to organophosphorus GO:0046683 102 0.015
activation of cysteine type endopeptidase activity GO:0097202 4 0.015
purine ribonucleoside catabolic process GO:0046130 124 0.014
establishment of protein localization GO:0045184 141 0.014
regulation of rna biosynthetic process GO:2001141 381 0.014
regulation of secretion GO:0051046 224 0.014
positive regulation of mitochondrion organization GO:0010822 4 0.014
regulation of catabolic process GO:0009894 113 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.014
guanosine containing compound metabolic process GO:1901068 74 0.014
positive regulation of protein dephosphorylation GO:0035307 4 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.014
response to alkaloid GO:0043279 132 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
hormone transport GO:0009914 121 0.014
aerobic respiration GO:0009060 13 0.014
regulation of phosphorus metabolic process GO:0051174 349 0.014
positive regulation of hydrolase activity GO:0051345 86 0.014
synaptic transmission GO:0007268 235 0.013
ribonucleoside monophosphate metabolic process GO:0009161 88 0.013
epithelium development GO:0060429 96 0.013
cellular response to hormone stimulus GO:0032870 247 0.013
cellular carbohydrate metabolic process GO:0044262 72 0.013
response to other organism GO:0051707 220 0.013
regulation of reactive oxygen species metabolic process GO:2000377 26 0.013
regulation of neuron projection development GO:0010975 161 0.013
positive regulation of phosphate metabolic process GO:0045937 262 0.013
circulatory system development GO:0072359 134 0.013
regulation of signal transduction GO:0009966 318 0.013
cation transport GO:0006812 382 0.013
positive regulation of transport GO:0051050 245 0.013
positive regulation of cell communication GO:0010647 271 0.013
secretion by cell GO:0032940 248 0.013
dicarboxylic acid catabolic process GO:0043649 1 0.013
inflammatory response GO:0006954 150 0.013
cellular chemical homeostasis GO:0055082 247 0.013
response to vitamin GO:0033273 131 0.013
cellular response to external stimulus GO:0071496 118 0.013
cellular response to peptide GO:1901653 133 0.013
cell projection organization GO:0030030 302 0.012
purine ribonucleotide catabolic process GO:0009154 136 0.012
behavior GO:0007610 205 0.012
negative regulation of hydrogen peroxide biosynthetic process GO:0010730 2 0.012
regulation of locomotion GO:0040012 148 0.012
regulation of transmembrane transport GO:0034762 122 0.012
regulation of hormone secretion GO:0046883 106 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
glial cell apoptotic process GO:0034349 8 0.012
protein transport GO:0015031 132 0.012
response to ethanol GO:0045471 162 0.012
cellular calcium ion homeostasis GO:0006874 160 0.012
positive regulation of cell development GO:0010720 176 0.012
calcium ion transport GO:0006816 131 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
cellular response to lipid GO:0071396 201 0.012
cell cell signaling GO:0007267 335 0.012
growth GO:0040007 165 0.012
anatomical structure morphogenesis GO:0009653 298 0.012
chromosome segregation GO:0007059 2 0.012
negative regulation of nucleic acid templated transcription GO:1903507 117 0.012
response to metal ion GO:0010038 253 0.012
regulation of ras protein signal transduction GO:0046578 45 0.012
multi multicellular organism process GO:0044706 138 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
glycosyl compound catabolic process GO:1901658 126 0.012
heart development GO:0007507 72 0.011
cellular ketone metabolic process GO:0042180 51 0.011
regulation of gtp catabolic process GO:0033124 58 0.011
single organism intracellular transport GO:1902582 166 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
response to hexose GO:0009746 144 0.011
positive regulation of cellular biosynthetic process GO:0031328 295 0.011
brain development GO:0007420 247 0.011
cation homeostasis GO:0055080 195 0.011
multi organism reproductive process GO:0044703 262 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
positive regulation of signaling GO:0023056 270 0.011
olfactory behavior GO:0042048 2 0.011
ion homeostasis GO:0050801 212 0.011
response to retinoic acid GO:0032526 63 0.011
signal release GO:0023061 145 0.011
regulation of transcription dna templated GO:0006355 374 0.011
response to growth factor GO:0070848 189 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
cell redox homeostasis GO:0045454 1 0.011
pyridine nucleotide metabolic process GO:0019362 28 0.011
regulation of anatomical structure size GO:0090066 135 0.011
cellular component biogenesis GO:0044085 368 0.011
cellular response to alcohol GO:0097306 87 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
response to biotic stimulus GO:0009607 226 0.011
regulation of cell projection organization GO:0031344 175 0.011
cellular response to nitrogen compound GO:1901699 210 0.011
response to estradiol GO:0032355 164 0.011
response to glucocorticoid GO:0051384 223 0.011
gtp metabolic process GO:0046039 72 0.011
guanosine containing compound catabolic process GO:1901069 71 0.011
interleukin 12 production GO:0032615 3 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
cellular protein localization GO:0034613 122 0.010
negative regulation of cell development GO:0010721 82 0.010
nad metabolic process GO:0019674 15 0.010
regulation of rna metabolic process GO:0051252 391 0.010
negative regulation of cell communication GO:0010648 158 0.010
central nervous system development GO:0007417 311 0.010
positive regulation of apoptotic process GO:0043065 154 0.010
single organism cellular localization GO:1902580 102 0.010
regulation of proteolysis GO:0030162 66 0.010
positive regulation of ion transport GO:0043270 94 0.010
regulation of cellular amine metabolic process GO:0033238 8 0.010
positive regulation of secretion by cell GO:1903532 128 0.010
divalent inorganic cation transport GO:0072511 134 0.010
divalent metal ion transport GO:0070838 132 0.010
antigen receptor mediated signaling pathway GO:0050851 1 0.010
cell morphogenesis GO:0000902 142 0.010

Dlat disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
central nervous system disease DOID:331 0 0.014
disease of metabolism DOID:0014667 0 0.013
inherited metabolic disorder DOID:655 0 0.013
amino acid metabolic disorder DOID:9252 0 0.012
organic acidemia DOID:0060159 0 0.012