|
|
positive regulation of excitatory postsynaptic membrane potential
|
GO:2000463 |
7 |
1.000
|
|
|
|
glutamate receptor signaling pathway
|
GO:0007215 |
43 |
0.999
|
|
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
25 |
0.990
|
|
|
|
positive regulation of membrane potential
|
GO:0045838 |
16 |
0.990
|
|
|
|
ionotropic glutamate receptor signaling pathway
|
GO:0035235 |
34 |
0.958
|
|
|
|
synaptic transmission
|
GO:0007268 |
235 |
0.952
|
|
|
|
single organism behavior
|
GO:0044708 |
130 |
0.951
|
Mouse Fly |
|
|
regulation of synaptic transmission
|
GO:0050804 |
141 |
0.941
|
|
|
|
cell cell signaling
|
GO:0007267 |
335 |
0.930
|
|
|
|
endocytosis
|
GO:0006897 |
84 |
0.901
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
1 |
0.895
|
Fly |
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
121 |
0.881
|
|
|
|
positive regulation of transport
|
GO:0051050 |
245 |
0.870
|
Rat |
|
|
receptor clustering
|
GO:0043113 |
13 |
0.858
|
|
|
|
postsynaptic membrane organization
|
GO:0001941 |
5 |
0.847
|
|
|
|
synapse organization
|
GO:0050808 |
46 |
0.837
|
|
|
|
single organism cellular localization
|
GO:1902580 |
102 |
0.827
|
|
|
|
synapse assembly
|
GO:0007416 |
29 |
0.822
|
|
|
|
neuron projection development
|
GO:0031175 |
273 |
0.803
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
19 |
0.790
|
|
|
|
behavior
|
GO:0007610 |
205 |
0.790
|
Mouse Fly |
|
|
synaptic vesicle exocytosis
|
GO:0016079 |
15 |
0.780
|
|
|
|
learning
|
GO:0007612 |
33 |
0.756
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
18 |
0.754
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
128 |
0.740
|
|
|
|
defecation
|
GO:0030421 |
1 |
0.736
|
|
|
|
neurotransmitter gated ion channel clustering
|
GO:0072578 |
3 |
0.730
|
|
|
|
regulation of cellular component organization
|
GO:0051128 |
368 |
0.728
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
134 |
0.722
|
|
|
|
protein localization to synapse
|
GO:0035418 |
5 |
0.719
|
|
|
|
cognition
|
GO:0050890 |
92 |
0.714
|
|
|
|
regulation of signal transduction
|
GO:0009966 |
318 |
0.710
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
19 |
0.705
|
|
|
|
rna metabolic process
|
GO:0016070 |
406 |
0.689
|
Fly |
|
|
regulation of rna metabolic process
|
GO:0051252 |
391 |
0.688
|
Fly |
|
|
neurological system process
|
GO:0050877 |
219 |
0.686
|
Mouse |
|
|
brain development
|
GO:0007420 |
247 |
0.684
|
|
|
|
single organism membrane organization
|
GO:0044802 |
74 |
0.682
|
|
|
|
regulation of ion transport
|
GO:0043269 |
245 |
0.682
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
122 |
0.669
|
|
|
|
dendritic spine morphogenesis
|
GO:0060997 |
9 |
0.645
|
|
|
|
secretion by cell
|
GO:0032940 |
248 |
0.645
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
48 |
0.632
|
|
|
|
rhythmic behavior
|
GO:0007622 |
24 |
0.632
|
Fly |
|
|
neuron projection morphogenesis
|
GO:0048812 |
122 |
0.631
|
|
|
|
regulation of n methyl d aspartate selective glutamate receptor activity
|
GO:2000310 |
6 |
0.603
|
|
|
|
associative learning
|
GO:0008306 |
19 |
0.602
|
|
|
|
regulation of inhibitory postsynaptic membrane potential
|
GO:0060080 |
6 |
0.590
|
|
|
|
response to fungicide
|
GO:0060992 |
20 |
0.589
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
123 |
0.582
|
|
|
|
neuron differentiation
|
GO:0030182 |
368 |
0.575
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
81 |
0.575
|
|
|
|
regulation of cellular localization
|
GO:0060341 |
263 |
0.574
|
|
|
|
neuron neuron synaptic transmission
|
GO:0007270 |
60 |
0.560
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
218 |
0.551
|
Fly |
|
|
ion transmembrane transport
|
GO:0034220 |
365 |
0.546
|
|
|
|
secretion
|
GO:0046903 |
307 |
0.539
|
|
|
|
regulation of glutamate receptor signaling pathway
|
GO:1900449 |
17 |
0.538
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
172 |
0.530
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
208 |
0.519
|
|
|
|
presynaptic membrane assembly
|
GO:0097105 |
3 |
0.512
|
|
|
|
regulation of synaptic vesicle endocytosis
|
GO:1900242 |
1 |
0.507
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
165 |
0.492
|
|
|
|
response to calcium ion
|
GO:0051592 |
59 |
0.478
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
1 |
0.474
|
Fly |
|
|
response to inorganic substance
|
GO:0010035 |
377 |
0.472
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
4 |
0.467
|
|
|
|
cellular component assembly
|
GO:0022607 |
360 |
0.465
|
|
|
|
cellular response to manganese ion
|
GO:0071287 |
5 |
0.456
|
|
|
|
postsynaptic density protein 95 clustering
|
GO:0097119 |
2 |
0.450
|
|
|
|
response to light stimulus
|
GO:0009416 |
52 |
0.439
|
Fly |
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
160 |
0.435
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
162 |
0.422
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
42 |
0.422
|
|
|
|
negative regulation of gamma aminobutyric acid secretion
|
GO:0014053 |
3 |
0.420
|
|
|
|
cell projection organization
|
GO:0030030 |
302 |
0.413
|
|
|
|
positive regulation of cell communication
|
GO:0010647 |
271 |
0.406
|
|
|
|
protein oligomerization
|
GO:0051259 |
191 |
0.394
|
|
|
|
receptor internalization
|
GO:0031623 |
14 |
0.387
|
|
|
|
negative regulation of vesicle fusion
|
GO:0031339 |
2 |
0.385
|
|
|
|
memory
|
GO:0007613 |
54 |
0.381
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
62 |
0.377
|
|
|
|
regulation of secretion
|
GO:0051046 |
224 |
0.376
|
|
|
|
neurotransmitter transport
|
GO:0006836 |
42 |
0.374
|
|
|
|
neuron development
|
GO:0048666 |
286 |
0.373
|
|
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
387 |
0.367
|
Fly |
|
|
phosphatidylinositol dephosphorylation
|
GO:0046856 |
4 |
0.364
|
|
|
|
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity
|
GO:2000311 |
11 |
0.361
|
|
|
|
organelle localization
|
GO:0051640 |
55 |
0.360
|
Mouse Fly |
|
|
chemosensory behavior
|
GO:0007635 |
2 |
0.360
|
|
|
|
neuromuscular process
|
GO:0050905 |
2 |
0.358
|
Mouse |
|
|
macromolecular complex assembly
|
GO:0065003 |
273 |
0.356
|
Human |
|
|
calcium ion transmembrane transport
|
GO:0070588 |
70 |
0.356
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
31 |
0.342
|
Mouse |
|
|
response to metal ion
|
GO:0010038 |
253 |
0.340
|
|
|
|
adult behavior
|
GO:0030534 |
16 |
0.338
|
|
|
|
central nervous system development
|
GO:0007417 |
311 |
0.336
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
89 |
0.334
|
|
|
|
forebrain development
|
GO:0030900 |
98 |
0.332
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
33 |
0.331
|
|
|
|
growth
|
GO:0040007 |
165 |
0.328
|
Fly |
|
|
cytoskeleton organization
|
GO:0007010 |
111 |
0.326
|
Fly |
|
|
telencephalon development
|
GO:0021537 |
62 |
0.318
|
|
|
|
membrane organization
|
GO:0061024 |
94 |
0.312
|
|
|
|
regulation of molecular function
|
GO:0065009 |
398 |
0.306
|
|
|
|
cation transport
|
GO:0006812 |
382 |
0.305
|
Rat |
|
|
regulation of developmental growth
|
GO:0048638 |
45 |
0.300
|
Fly |
|
|
metal ion homeostasis
|
GO:0055065 |
186 |
0.299
|
|
|
|
negative regulation of calcium ion dependent exocytosis
|
GO:0045955 |
5 |
0.296
|
|
|
|
response to manganese ion
|
GO:0010042 |
13 |
0.294
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
229 |
0.293
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.292
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
42 |
0.291
|
|
|
|
metal ion transport
|
GO:0030001 |
289 |
0.285
|
Rat |
|
|
macromolecular complex subunit organization
|
GO:0043933 |
339 |
0.285
|
Human |
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
106 |
0.283
|
|
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
346 |
0.282
|
|
|
|
positive regulation of glutamate secretion
|
GO:0014049 |
8 |
0.282
|
|
|
|
axon development
|
GO:0061564 |
96 |
0.281
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
123 |
0.274
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
29 |
0.274
|
|
|
|
synaptic transmission glutamatergic
|
GO:0035249 |
33 |
0.272
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
155 |
0.269
|
|
|
|
tissue development
|
GO:0009888 |
252 |
0.260
|
Fly |
|
|
positive regulation of synaptic vesicle endocytosis
|
GO:1900244 |
1 |
0.258
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
70 |
0.257
|
Mouse |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
200 |
0.253
|
Fly |
|
|
positive regulation of synaptic vesicle recycling
|
GO:1903423 |
1 |
0.249
|
|
|
|
regulation of synapse structure and activity
|
GO:0050803 |
21 |
0.249
|
Fly |
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
252 |
0.248
|
Fly |
|
|
regulation of phosphatidylinositol dephosphorylation
|
GO:0060304 |
1 |
0.242
|
|
|
|
exocytosis
|
GO:0006887 |
60 |
0.242
|
|
|
|
learning or memory
|
GO:0007611 |
90 |
0.241
|
|
|
|
regulation of growth
|
GO:0040008 |
105 |
0.240
|
Fly |
|
|
regulation of synaptic vesicle exocytosis
|
GO:2000300 |
6 |
0.238
|
|
|
|
nucleic acid templated transcription
|
GO:0097659 |
379 |
0.238
|
Fly |
|
|
cardiac muscle cell contraction
|
GO:0086003 |
10 |
0.237
|
|
|
|
regulation of synaptic vesicle transport
|
GO:1902803 |
6 |
0.236
|
|
|
|
protein localization
|
GO:0008104 |
191 |
0.233
|
|
|
|
response to ethanol
|
GO:0045471 |
162 |
0.231
|
|
|
|
locomotory exploration behavior
|
GO:0035641 |
1 |
0.227
|
Mouse |
|
|
protein complex biogenesis
|
GO:0070271 |
263 |
0.226
|
Human |
|
|
cellular protein localization
|
GO:0034613 |
122 |
0.226
|
|
|
|
membrane hyperpolarization
|
GO:0060081 |
11 |
0.222
|
|
|
|
cellular homeostasis
|
GO:0019725 |
252 |
0.219
|
|
|
|
protein tetramerization
|
GO:0051262 |
38 |
0.218
|
|
|
|
olfactory learning
|
GO:0008355 |
1 |
0.218
|
|
|
|
positive regulation of signaling
|
GO:0023056 |
270 |
0.217
|
|
|
|
protein complex subunit organization
|
GO:0071822 |
302 |
0.215
|
Human |
|
|
regulation of respiratory gaseous exchange
|
GO:0043576 |
2 |
0.213
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
140 |
0.209
|
|
|
|
regulation of synapse organization
|
GO:0050807 |
19 |
0.208
|
Fly |
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
62 |
0.207
|
|
|
|
n methyl d aspartate receptor clustering
|
GO:0097114 |
2 |
0.206
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
94 |
0.205
|
Rat |
|
|
positive regulation of response to stimulus
|
GO:0048584 |
285 |
0.204
|
|
|
|
sensory perception
|
GO:0007600 |
101 |
0.203
|
|
|
|
rhythmic synaptic transmission
|
GO:0060024 |
1 |
0.201
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
208 |
0.201
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
181 |
0.201
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
87 |
0.198
|
|
|
|
detection of calcium ion
|
GO:0005513 |
1 |
0.198
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
140 |
0.195
|
|
|
|
signal release
|
GO:0023061 |
145 |
0.195
|
|
|
|
protein complex assembly
|
GO:0006461 |
263 |
0.195
|
Human |
|
|
cellular cation homeostasis
|
GO:0030003 |
180 |
0.190
|
|
|
|
dendrite morphogenesis
|
GO:0048813 |
43 |
0.190
|
|
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
1 |
0.190
|
Fly |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
202 |
0.183
|
|
|
|
cgmp catabolic process
|
GO:0046069 |
6 |
0.183
|
|
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
197 |
0.182
|
|
|
|
response to radiation
|
GO:0009314 |
137 |
0.178
|
Fly |
|
|
regulation of catecholamine secretion
|
GO:0050433 |
32 |
0.178
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
119 |
0.176
|
|
|
|
macromolecule localization
|
GO:0033036 |
252 |
0.173
|
|
|
|
head development
|
GO:0060322 |
247 |
0.172
|
|
|
|
response to alkaloid
|
GO:0043279 |
132 |
0.169
|
|
|
|
negative regulation of epinephrine secretion
|
GO:0032811 |
6 |
0.168
|
|
|
|
regulation of amine transport
|
GO:0051952 |
54 |
0.168
|
|
|
|
locomotion
|
GO:0040011 |
237 |
0.167
|
Fly |
|
|
regulation of transporter activity
|
GO:0032409 |
50 |
0.166
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
80 |
0.164
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
106 |
0.159
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
162 |
0.157
|
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
381 |
0.157
|
Fly |
|
|
cellular component biogenesis
|
GO:0044085 |
368 |
0.157
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
134 |
0.155
|
|
|
|
embryonic pattern specification
|
GO:0009880 |
1 |
0.155
|
Fly |
|
|
cell growth
|
GO:0016049 |
104 |
0.153
|
|
|
|
negative regulation of nucleic acid templated transcription
|
GO:1903507 |
117 |
0.151
|
Fly |
|
|
anterior posterior pattern specification
|
GO:0009952 |
1 |
0.150
|
Fly |
|
|
regulation of synaptic vesicle recycling
|
GO:1903421 |
1 |
0.150
|
|
|
|
limbic system development
|
GO:0021761 |
38 |
0.150
|
|
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
234 |
0.149
|
Fly |
|
|
regulation of nervous system development
|
GO:0051960 |
264 |
0.148
|
Fly |
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
38 |
0.148
|
|
|
|
amine transport
|
GO:0015837 |
57 |
0.147
|
|
|
|
positive regulation of gene expression
|
GO:0010628 |
244 |
0.145
|
|
|
|
muscle system process
|
GO:0003012 |
115 |
0.144
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
319 |
0.144
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
184 |
0.141
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
229 |
0.140
|
|
|
|
developmental growth
|
GO:0048589 |
100 |
0.139
|
Fly |
|
|
regulation of neuron projection development
|
GO:0010975 |
161 |
0.134
|
|
|
|
positive regulation of long term synaptic potentiation
|
GO:1900273 |
4 |
0.134
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
334 |
0.133
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
349 |
0.133
|
|
|
|
membrane depolarization
|
GO:0051899 |
32 |
0.132
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
37 |
0.131
|
Mouse Fly |
|
|
negative regulation of cellular macromolecule biosynthetic process
|
GO:2000113 |
141 |
0.131
|
Fly |
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
17 |
0.130
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
117 |
0.130
|
|
|
|
camp metabolic process
|
GO:0046058 |
63 |
0.130
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
349 |
0.129
|
|
|
|
sensory perception of pain
|
GO:0019233 |
73 |
0.128
|
|
|
|
amino acid transport
|
GO:0006865 |
70 |
0.126
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
319 |
0.126
|
|
|
|
rhythmic process
|
GO:0048511 |
156 |
0.126
|
Fly |
|
|
negative regulation of response to stimulus
|
GO:0048585 |
155 |
0.125
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
380 |
0.125
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
37 |
0.125
|
|
|
|
dicarboxylic acid transport
|
GO:0006835 |
34 |
0.124
|
|
|
|
calcium ion transport
|
GO:0006816 |
131 |
0.124
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
157 |
0.123
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
249 |
0.120
|
|
|
|
response to toxic substance
|
GO:0009636 |
133 |
0.119
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.118
|
|
|
|
synaptic transmission gabaergic
|
GO:0051932 |
22 |
0.116
|
|
|
|
positive regulation of calcium ion dependent exocytosis
|
GO:0045956 |
6 |
0.116
|
|
|
|
regulation of long term neuronal synaptic plasticity
|
GO:0048169 |
15 |
0.116
|
Mouse |
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
197 |
0.114
|
|
|
|
response to cocaine
|
GO:0042220 |
39 |
0.114
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
279 |
0.112
|
|
|
|
detection of stimulus
|
GO:0051606 |
24 |
0.112
|
|
|
|
response to amphetamine
|
GO:0001975 |
25 |
0.112
|
|
|
|
transcription dna templated
|
GO:0006351 |
377 |
0.111
|
Fly |
|
|
regulation of cell differentiation
|
GO:0045595 |
320 |
0.111
|
|
|
|
reproductive process
|
GO:0022414 |
372 |
0.110
|
Worm Fly |
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
227 |
0.110
|
|
|
|
olfactory behavior
|
GO:0042048 |
2 |
0.110
|
|
|
|
response to cytokine
|
GO:0034097 |
215 |
0.109
|
|
|
|
cellular macromolecule localization
|
GO:0070727 |
122 |
0.109
|
|
|
|
regulation of protein localization
|
GO:0032880 |
81 |
0.109
|
Rat |
|
|
regulation of behavior
|
GO:0050795 |
61 |
0.108
|
Mouse |
|
|
ribonucleotide metabolic process
|
GO:0009259 |
231 |
0.107
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
178 |
0.106
|
Fly |
|
|
cell fate commitment involved in pattern specification
|
GO:0060581 |
2 |
0.105
|
Fly |
|
|
homeostatic process
|
GO:0042592 |
331 |
0.104
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
28 |
0.103
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
316 |
0.102
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
176 |
0.099
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
165 |
0.099
|
|
|
|
anatomical structure morphogenesis
|
GO:0009653 |
298 |
0.099
|
|
|
|
serotonin metabolic process
|
GO:0042428 |
3 |
0.098
|
|
|
|
endoplasmic reticulum membrane organization
|
GO:0090158 |
1 |
0.098
|
|
|
|
circadian behavior
|
GO:0048512 |
24 |
0.097
|
Fly |
|
|
protein localization to membrane
|
GO:0072657 |
36 |
0.097
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
187 |
0.097
|
|
|
|
pallium development
|
GO:0021543 |
42 |
0.097
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
110 |
0.096
|
|
|
|
synaptic vesicle localization
|
GO:0097479 |
24 |
0.095
|
Mouse |
|
|
response to ammonium ion
|
GO:0060359 |
71 |
0.094
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
125 |
0.091
|
|
|
|
glutamate secretion
|
GO:0014047 |
19 |
0.091
|
|
|
|
camera type eye development
|
GO:0043010 |
48 |
0.089
|
|
|
|
hippocampus development
|
GO:0021766 |
30 |
0.088
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
122 |
0.087
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
80 |
0.087
|
|
|
|
organic anion transport
|
GO:0015711 |
132 |
0.087
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
21 |
0.084
|
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
295 |
0.084
|
|
|
|
organophosphate metabolic process
|
GO:0019637 |
370 |
0.084
|
|
|
|
monoamine transport
|
GO:0015844 |
43 |
0.084
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
235 |
0.083
|
|
|
|
single organism organelle organization
|
GO:1902589 |
180 |
0.082
|
Mouse Fly |
|
|
regulation of heart contraction
|
GO:0008016 |
48 |
0.081
|
|
|
|
detection of abiotic stimulus
|
GO:0009582 |
13 |
0.081
|
|
|
|
negative regulation of gene expression
|
GO:0010629 |
199 |
0.081
|
Fly |
|
|
organelle organization
|
GO:0006996 |
266 |
0.081
|
Mouse Fly |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
377 |
0.079
|
|
|
|
response to peptide
|
GO:1901652 |
292 |
0.079
|
|
|
|
respiratory gaseous exchange
|
GO:0007585 |
4 |
0.079
|
|
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
203 |
0.078
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
115 |
0.078
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
98 |
0.078
|
|
|
|
response to histamine
|
GO:0034776 |
3 |
0.077
|
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
7 |
0.077
|
|
|
|
adenylate cyclase inhibiting g protein coupled receptor signaling pathway
|
GO:0007193 |
19 |
0.076
|
|
|
|
regulation of transcription dna templated
|
GO:0006355 |
374 |
0.076
|
Fly |
|
|
heart morphogenesis
|
GO:0003007 |
3 |
0.075
|
|
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
380 |
0.075
|
Fly |
|
|
negative regulation of adenylate cyclase activity
|
GO:0007194 |
7 |
0.075
|
|
|
|
blood circulation
|
GO:0008015 |
183 |
0.075
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
376 |
0.075
|
Fly |
|
|
macromolecule catabolic process
|
GO:0009057 |
58 |
0.074
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
87 |
0.074
|
|
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
197 |
0.074
|
|
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
262 |
0.074
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
49 |
0.074
|
|
|
|
locomotory behavior
|
GO:0007626 |
15 |
0.073
|
Mouse Fly |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
177 |
0.073
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
63 |
0.073
|
|
|
|
protein catabolic process
|
GO:0030163 |
30 |
0.073
|
|
|
|
cation homeostasis
|
GO:0055080 |
195 |
0.073
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
124 |
0.072
|
|
|
|
regulation of neurotransmitter transport
|
GO:0051588 |
21 |
0.072
|
|
|
|
male mating behavior
|
GO:0060179 |
3 |
0.072
|
Fly |
|
|
chemical homeostasis
|
GO:0048878 |
292 |
0.072
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
172 |
0.072
|
Rat |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
157 |
0.071
|
|
|
|
positive regulation of growth
|
GO:0045927 |
55 |
0.071
|
Fly |
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
126 |
0.071
|
|
|
|
presynaptic membrane organization
|
GO:0097090 |
4 |
0.071
|
|
|
|
response to nicotine
|
GO:0035094 |
51 |
0.070
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
262 |
0.070
|
Worm Fly |
|
|
positive regulation of signal transduction
|
GO:0009967 |
175 |
0.069
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
25 |
0.069
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
304 |
0.067
|
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
247 |
0.067
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
283 |
0.067
|
|
|
|
regulation of dendrite development
|
GO:0050773 |
59 |
0.067
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
116 |
0.066
|
Fly |
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
260 |
0.066
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
359 |
0.066
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
51 |
0.065
|
|
|
|
positive regulation of heart contraction
|
GO:0045823 |
15 |
0.065
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
4 |
0.065
|
|
|
|
cellular response to magnesium starvation
|
GO:0010350 |
1 |
0.065
|
|
|
|
eye development
|
GO:0001654 |
50 |
0.065
|
|
|
|
vesicle localization
|
GO:0051648 |
33 |
0.064
|
Mouse |
|
|
synaptic vesicle recycling
|
GO:0036465 |
5 |
0.064
|
Mouse |
|
|
positive regulation of cell projection organization
|
GO:0031346 |
111 |
0.064
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
154 |
0.064
|
|
|
|
desensitization of g protein coupled receptor protein signaling pathway
|
GO:0002029 |
10 |
0.064
|
|
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
161 |
0.064
|
Fly |
|
|
regulation of cell development
|
GO:0060284 |
263 |
0.064
|
|
|
|
sleep
|
GO:0030431 |
30 |
0.063
|
|
|
|
rna biosynthetic process
|
GO:0032774 |
380 |
0.063
|
Fly |
|
|
negative regulation of secretion by cell
|
GO:1903531 |
72 |
0.063
|
|
|
|
regulation of amino acid transport
|
GO:0051955 |
25 |
0.062
|
|
|
|
response to nutrient
|
GO:0007584 |
248 |
0.062
|
|
|
|
detection of chemical stimulus
|
GO:0009593 |
10 |
0.062
|
|
|
|
receptor metabolic process
|
GO:0043112 |
18 |
0.062
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
253 |
0.061
|
|
|
|
single organism reproductive process
|
GO:0044702 |
297 |
0.061
|
Worm Fly |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
136 |
0.061
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
118 |
0.061
|
Rat |
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
23 |
0.060
|
Fly |
|
|
protein heterooligomerization
|
GO:0051291 |
89 |
0.060
|
|
|
|
positive regulation of the force of heart contraction by epinephrine
|
GO:0003059 |
1 |
0.060
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
96 |
0.059
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
99 |
0.059
|
|
|
|
axonogenesis
|
GO:0007409 |
71 |
0.058
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
140 |
0.058
|
|
|
|
regulation of phosphorylation
|
GO:0042325 |
248 |
0.058
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
138 |
0.057
|
Fly |
|
|
retina morphogenesis in camera type eye
|
GO:0060042 |
1 |
0.057
|
|
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
123 |
0.057
|
Fly |
|
|
peptide transport
|
GO:0015833 |
97 |
0.057
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
49 |
0.057
|
Fly |
|
|
cell morphogenesis
|
GO:0000902 |
142 |
0.057
|
|
|
|
positive regulation of peptide hormone secretion
|
GO:0090277 |
50 |
0.056
|
|
|
|
hormone transport
|
GO:0009914 |
121 |
0.055
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
82 |
0.054
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
75 |
0.054
|
Fly |
|
|
establishment of protein localization
|
GO:0045184 |
141 |
0.053
|
Human |
|
|
response to transition metal nanoparticle
|
GO:1990267 |
122 |
0.053
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
31 |
0.053
|
Mouse |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
136 |
0.052
|
|
|
|
positive regulation of developmental growth
|
GO:0048639 |
29 |
0.052
|
Fly |
|
|
prepulse inhibition
|
GO:0060134 |
1 |
0.052
|
|
|
|
nucleobase containing compound catabolic process
|
GO:0034655 |
152 |
0.052
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
167 |
0.052
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
80 |
0.051
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
42 |
0.051
|
|
|
|
negative regulation of exocytosis
|
GO:0045920 |
7 |
0.051
|
|
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
161 |
0.050
|
Fly |
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
153 |
0.050
|
Fly |
|
|
negative adaptation of signaling pathway
|
GO:0022401 |
10 |
0.050
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
202 |
0.050
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
102 |
0.050
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
2 |
0.049
|
|
|
|
regulation of protein modification process
|
GO:0031399 |
194 |
0.049
|
|
|
|
axis specification
|
GO:0009798 |
4 |
0.049
|
Fly |
|
|
cellular response to magnesium ion
|
GO:0071286 |
4 |
0.048
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
138 |
0.048
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
51 |
0.048
|
|
|
|
spinal cord development
|
GO:0021510 |
27 |
0.048
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
43 |
0.048
|
|
|
|
positive regulation of phosphate metabolic process
|
GO:0045937 |
262 |
0.048
|
|
|
|
single organism intracellular transport
|
GO:1902582 |
166 |
0.048
|
|
|
|
intracellular transport
|
GO:0046907 |
185 |
0.047
|
|
|
|
regulation of insulin secretion
|
GO:0050796 |
65 |
0.047
|
|
|
|
regulation of vesicle fusion
|
GO:0031338 |
6 |
0.047
|
|
|
|
embryonic axis specification
|
GO:0000578 |
1 |
0.047
|
Fly |
|
|
detection of external stimulus
|
GO:0009581 |
13 |
0.047
|
|
|
|
amide transport
|
GO:0042886 |
105 |
0.047
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
184 |
0.047
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
84 |
0.047
|
|
|
|
dopamine transport
|
GO:0015872 |
18 |
0.047
|
|
|
|
positive regulation of synaptic vesicle exocytosis
|
GO:2000302 |
3 |
0.046
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
203 |
0.046
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
175 |
0.046
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
27 |
0.046
|
|
|
|
potassium ion transport
|
GO:0006813 |
97 |
0.046
|
Rat |
|
|
neuromuscular synaptic transmission
|
GO:0007274 |
2 |
0.045
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
115 |
0.045
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
55 |
0.045
|
|
|
|
actin filament based movement
|
GO:0030048 |
16 |
0.045
|
|
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
167 |
0.045
|
|
|
|
striated muscle contraction
|
GO:0006941 |
44 |
0.044
|
|
|
|
catecholamine transport
|
GO:0051937 |
37 |
0.044
|
|
|
|
calcium ion dependent exocytosis
|
GO:0017156 |
16 |
0.044
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
247 |
0.043
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
83 |
0.043
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
85 |
0.042
|
|
|
|
actin filament based process
|
GO:0030029 |
86 |
0.042
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
233 |
0.042
|
Worm Fly |
|
|
positive regulation of hormone secretion
|
GO:0046887 |
65 |
0.042
|
|
|
|
positive regulation of intracellular signal transduction
|
GO:1902533 |
138 |
0.042
|
|
|
|
positive regulation of vesicle fusion
|
GO:0031340 |
4 |
0.042
|
|
|
|
response to testosterone
|
GO:0033574 |
55 |
0.041
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
143 |
0.041
|
|
|
|
endoplasmic reticulum organization
|
GO:0007029 |
1 |
0.041
|
|
|
|
positive regulation of molecular function
|
GO:0044093 |
230 |
0.040
|
|
|
|
organic acid transport
|
GO:0015849 |
116 |
0.040
|
|
|
|
epinephrine secretion
|
GO:0048242 |
6 |
0.040
|
|
|
|
startle response
|
GO:0001964 |
2 |
0.039
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
135 |
0.039
|
|
|
|
cellular component movement
|
GO:0006928 |
248 |
0.039
|
|
|
|
positive regulation of blood pressure by epinephrine norepinephrine
|
GO:0003321 |
2 |
0.039
|
|
|
|
negative regulation of cardiac muscle tissue growth
|
GO:0055022 |
3 |
0.038
|
|
|
|
mapk cascade
|
GO:0000165 |
140 |
0.038
|
|
|
|
visual learning
|
GO:0008542 |
8 |
0.038
|
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
289 |
0.038
|
|
|
|
l glutamate import
|
GO:0051938 |
2 |
0.038
|
|
|
|
mating
|
GO:0007618 |
22 |
0.038
|
Fly |
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
242 |
0.038
|
|
|
|
positive regulation of synaptic vesicle transport
|
GO:1902805 |
3 |
0.038
|
|
|
|
response to estrogen
|
GO:0043627 |
232 |
0.038
|
|
|
|
long term memory
|
GO:0007616 |
15 |
0.037
|
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
1 |
0.037
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
281 |
0.037
|
|
|
|
cerebral cortex development
|
GO:0021987 |
18 |
0.037
|
|
|
|
dopamine secretion
|
GO:0014046 |
15 |
0.037
|
|
|
|
g protein coupled acetylcholine receptor signaling pathway
|
GO:0007213 |
5 |
0.036
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter
|
GO:0045944 |
148 |
0.036
|
|
|
|
regulation of locomotion
|
GO:0040012 |
148 |
0.036
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
144 |
0.036
|
|
|
|
vesicle organization
|
GO:0016050 |
29 |
0.036
|
Mouse |
|
|
negative regulation of purine nucleotide biosynthetic process
|
GO:1900372 |
12 |
0.036
|
|
|
|
regulation of receptor internalization
|
GO:0002090 |
6 |
0.036
|
|
|
|
negative regulation of camp biosynthetic process
|
GO:0030818 |
12 |
0.036
|
|
|
|
regulation of actin filament based movement
|
GO:1903115 |
12 |
0.035
|
|
|
|
dephosphorylation
|
GO:0016311 |
98 |
0.035
|
|
|
|
regulation of organic acid transport
|
GO:0032890 |
35 |
0.035
|
|
|
|
axon extension
|
GO:0048675 |
26 |
0.034
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
80 |
0.034
|
|
|
|
male germ line stem cell asymmetric division
|
GO:0048133 |
1 |
0.034
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
247 |
0.034
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
386 |
0.034
|
|
|
|
negative regulation of transport
|
GO:0051051 |
136 |
0.034
|
|
|
|
regulation of circadian sleep wake cycle sleep
|
GO:0045187 |
18 |
0.034
|
|
|
|
response to wounding
|
GO:0009611 |
254 |
0.034
|
|
|
|
negative regulation of cyclic nucleotide metabolic process
|
GO:0030800 |
15 |
0.034
|
|
|
|
regulation of protein transport
|
GO:0051223 |
68 |
0.033
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
124 |
0.033
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
46 |
0.033
|
|
|
|
positive regulation of ion transmembrane transport
|
GO:0034767 |
24 |
0.033
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
217 |
0.033
|
|
|
|
regulation of catabolic process
|
GO:0009894 |
113 |
0.033
|
|
|
|
regulation of anion transport
|
GO:0044070 |
43 |
0.033
|
|
|
|
intraspecies interaction between organisms
|
GO:0051703 |
15 |
0.033
|
Mouse |
|
|
g protein coupled glutamate receptor signaling pathway
|
GO:0007216 |
8 |
0.032
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
141 |
0.032
|
|
|
|
protein localization to organelle
|
GO:0033365 |
57 |
0.032
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
175 |
0.032
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
1 |
0.032
|
|
|
|
negative regulation of metabolic process
|
GO:0009892 |
331 |
0.031
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
147 |
0.031
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
75 |
0.031
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
267 |
0.031
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
82 |
0.031
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
168 |
0.031
|
|
|
|
apoptotic process
|
GO:0006915 |
381 |
0.031
|
|
|
|
feeding behavior
|
GO:0007631 |
53 |
0.031
|
|
|
|
locomotor rhythm
|
GO:0045475 |
1 |
0.030
|
Fly |
|
|
positive regulation of developmental process
|
GO:0051094 |
283 |
0.030
|
Fly |
|
|
negative regulation of cell communication
|
GO:0010648 |
158 |
0.030
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
91 |
0.030
|
|
|
|
cell activation
|
GO:0001775 |
97 |
0.029
|
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
168 |
0.029
|
Fly |
|
|
intracellular signal transduction
|
GO:0035556 |
314 |
0.029
|
Fly |
