Rattus norvegicus

8 known processes

Dlk1

delta-like 1 homolog (Drosophila)

(Aliases: Zog,Pref-1)

Dlk1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to endogenous stimulus GO:0071495 377 0.243
regulation of cell differentiation GO:0045595 320 0.234
Rat
response to peptide GO:1901652 292 0.208
response to peptide hormone GO:0043434 278 0.172
response to inorganic substance GO:0010035 377 0.152
regulation of cellular component organization GO:0051128 368 0.130
macromolecular complex subunit organization GO:0043933 339 0.129
neurological system process GO:0050877 219 0.126
regulation of transcription dna templated GO:0006355 374 0.112
g protein coupled receptor signaling pathway GO:0007186 242 0.110
multicellular organismal reproductive process GO:0048609 233 0.107
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.105
positive regulation of cellular biosynthetic process GO:0031328 295 0.103
vesicle mediated transport GO:0016192 181 0.094
cellular component biogenesis GO:0044085 368 0.094
response to bacterium GO:0009617 200 0.094
reproductive process GO:0022414 372 0.094
Rat
positive regulation of cell communication GO:0010647 271 0.092
negative regulation of cell death GO:0060548 229 0.091
response to other organism GO:0051707 220 0.089
intracellular signal transduction GO:0035556 314 0.088
response to extracellular stimulus GO:0009991 380 0.088
regulation of catalytic activity GO:0050790 304 0.088
lipid metabolic process GO:0006629 283 0.088
locomotion GO:0040011 237 0.086
response to estradiol GO:0032355 164 0.084
regulation of neurogenesis GO:0050767 247 0.083
Rat
regulation of phosphate metabolic process GO:0019220 349 0.080
single organism reproductive process GO:0044702 297 0.077
Rat
regulation of rna biosynthetic process GO:2001141 381 0.077
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.075
rhythmic process GO:0048511 156 0.072
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.070
reproduction GO:0000003 245 0.068
Rat
sexual reproduction GO:0019953 148 0.067
Rat
apoptotic process GO:0006915 381 0.066
cellular response to peptide GO:1901653 133 0.064
multicellular organism reproduction GO:0032504 233 0.063
Rat
reproductive system development GO:0061458 128 0.062
Rat
transcription dna templated GO:0006351 377 0.062
tissue development GO:0009888 252 0.062
Rat
organelle organization GO:0006996 266 0.061
regulation of multicellular organismal development GO:2000026 376 0.061
Rat
regulation of nervous system development GO:0051960 264 0.060
Rat
neuron death GO:0070997 127 0.060
positive regulation of transcription dna templated GO:0045893 197 0.059
positive regulation of gene expression GO:0010628 244 0.059
response to nutrient GO:0007584 248 0.058
positive regulation of signaling GO:0023056 270 0.058
positive regulation of biosynthetic process GO:0009891 319 0.056
response to biotic stimulus GO:0009607 226 0.056
nucleobase containing small molecule metabolic process GO:0055086 316 0.055
regulation of signal transduction GO:0009966 318 0.054
Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.054
inflammatory response GO:0006954 150 0.053
positive regulation of nervous system development GO:0051962 178 0.052
Rat
cellular response to oxygen containing compound GO:1901701 386 0.051
response to wounding GO:0009611 254 0.051
regulation of hormone levels GO:0010817 187 0.049
response to acid chemical GO:0001101 222 0.049
cell motility GO:0048870 202 0.049
cytoskeleton organization GO:0007010 111 0.049
positive regulation of rna metabolic process GO:0051254 203 0.049
cellular response to hormone stimulus GO:0032870 247 0.047
protein heterooligomerization GO:0051291 89 0.047
positive regulation of response to stimulus GO:0048584 285 0.046
growth GO:0040007 165 0.046
response to external biotic stimulus GO:0043207 221 0.045
reproductive structure development GO:0048608 128 0.045
Rat
regulation of cell development GO:0060284 263 0.045
Rat
cell cell signaling GO:0007267 335 0.045
positive regulation of hormone secretion GO:0046887 65 0.045
response to metal ion GO:0010038 253 0.044
regulation of apoptotic process GO:0042981 335 0.044
regulation of neuron differentiation GO:0045664 208 0.043
response to hydrogen peroxide GO:0042542 89 0.043
response to corticosteroid GO:0031960 235 0.043
epithelium development GO:0060429 96 0.042
Rat
response to nutrient levels GO:0031667 370 0.042
cellular response to peptide hormone stimulus GO:0071375 120 0.041
positive regulation of multicellular organismal process GO:0051240 387 0.040
Rat
positive regulation of nucleic acid templated transcription GO:1903508 197 0.040
regulation of intracellular signal transduction GO:1902531 218 0.040
regulation of cellular localization GO:0060341 263 0.040
response to light stimulus GO:0009416 52 0.038
cellular response to organonitrogen compound GO:0071417 197 0.038
cellular response to nitrogen compound GO:1901699 210 0.037
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.037
positive regulation of rna biosynthetic process GO:1902680 197 0.037
nucleic acid templated transcription GO:0097659 379 0.037
response to ethanol GO:0045471 162 0.037
regulation of cell proliferation GO:0042127 359 0.037
Rat
adult locomotory behavior GO:0008344 4 0.036
response to glucocorticoid GO:0051384 223 0.036
single organism biosynthetic process GO:0044711 342 0.035
protein complex subunit organization GO:0071822 302 0.034
rna metabolic process GO:0016070 406 0.034
positive regulation of signal transduction GO:0009967 175 0.034
regulation of phosphorylation GO:0042325 248 0.034
single organism intracellular transport GO:1902582 166 0.034
cellular response to organic cyclic compound GO:0071407 202 0.034
anatomical structure morphogenesis GO:0009653 298 0.033
positive regulation of cell proliferation GO:0008284 249 0.033
action potential GO:0001508 54 0.033
cellular component movement GO:0006928 248 0.033
immune system process GO:0002376 204 0.033
response to estrogen GO:0043627 232 0.032
programmed cell death GO:0012501 392 0.031
protein complex biogenesis GO:0070271 263 0.031
cellular component assembly GO:0022607 360 0.031
regulation of kinase activity GO:0043549 117 0.031
transcription from rna polymerase ii promoter GO:0006366 252 0.030
response to growth factor GO:0070848 189 0.030
multi organism reproductive process GO:0044703 262 0.030
Rat
cellular response to growth factor stimulus GO:0071363 162 0.030
spermatogenesis GO:0007283 99 0.030
Rat
regulation of muscle contraction GO:0006937 53 0.029
negative regulation of cellular metabolic process GO:0031324 281 0.029
multicellular organismal signaling GO:0035637 44 0.029
organophosphate metabolic process GO:0019637 370 0.029
cellular response to lipid GO:0071396 201 0.029
positive regulation of cell death GO:0010942 184 0.028
rna biosynthetic process GO:0032774 380 0.028
regulation of secretion GO:0051046 224 0.028
circadian rhythm GO:0007623 88 0.028
purine containing compound metabolic process GO:0072521 253 0.028
learning or memory GO:0007611 90 0.028
carbohydrate derivative metabolic process GO:1901135 346 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.027
intracellular transport GO:0046907 185 0.027
negative regulation of cell differentiation GO:0045596 99 0.027
Rat
negative regulation of cellular biosynthetic process GO:0031327 161 0.027
phospholipid metabolic process GO:0006644 61 0.027
positive regulation of developmental process GO:0051094 283 0.027
Rat
heart contraction GO:0060047 57 0.026
response to alkaloid GO:0043279 132 0.026
response to nicotine GO:0035094 51 0.026
defense response GO:0006952 194 0.026
positive regulation of intracellular signal transduction GO:1902533 138 0.026
nucleotide metabolic process GO:0009117 279 0.026
negative regulation of biosynthetic process GO:0009890 168 0.026
response to cytokine GO:0034097 215 0.025
cellular response to steroid hormone stimulus GO:0071383 93 0.025
response to radiation GO:0009314 137 0.025
response to hypoxia GO:0001666 231 0.025
Rat
regulation of neuron death GO:1901214 115 0.024
cation transport GO:0006812 382 0.024
regulation of neuron apoptotic process GO:0043523 83 0.024
gliogenesis GO:0042063 93 0.024
Rat
response to oxidative stress GO:0006979 186 0.024
response to ketone GO:1901654 182 0.024
negative regulation of developmental process GO:0051093 125 0.024
Rat
regulation of immune system process GO:0002682 123 0.024
secretion GO:0046903 307 0.024
positive regulation of phosphorus metabolic process GO:0010562 262 0.023
regulation of secretion by cell GO:1903530 208 0.023
learning GO:0007612 33 0.023
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.023
negative regulation of metabolic process GO:0009892 331 0.023
macromolecular complex assembly GO:0065003 273 0.023
single organism behavior GO:0044708 130 0.023
regulation of protein metabolic process GO:0051246 289 0.023
neuron projection morphogenesis GO:0048812 122 0.023
positive regulation of phosphorylation GO:0042327 177 0.023
negative regulation of transport GO:0051051 136 0.022
regulation of cellular protein metabolic process GO:0032268 267 0.022
sensory perception GO:0007600 101 0.022
purine ribonucleotide metabolic process GO:0009150 227 0.022
response to camp GO:0051591 91 0.022
regulation of lipid metabolic process GO:0019216 68 0.022
gland development GO:0048732 155 0.022
cyclic nucleotide metabolic process GO:0009187 80 0.022
response to molecule of fungal origin GO:0002238 3 0.022
cellular lipid metabolic process GO:0044255 208 0.022
positive regulation of neurogenesis GO:0050769 165 0.022
Rat
single organism catabolic process GO:0044712 283 0.021
response to lipopolysaccharide GO:0032496 191 0.021
brain development GO:0007420 247 0.021
Rat
glycerolipid metabolic process GO:0046486 67 0.021
regulation of rna metabolic process GO:0051252 391 0.021
positive regulation of kinase activity GO:0033674 77 0.021
cell morphogenesis involved in differentiation GO:0000904 119 0.021
development of primary sexual characteristics GO:0045137 107 0.021
Rat
actin filament based process GO:0030029 86 0.021
amino acid transmembrane transport GO:0003333 33 0.021
gamete generation GO:0007276 124 0.021
Rat
positive regulation of protein metabolic process GO:0051247 178 0.021
regulation of cell projection size GO:0032536 1 0.021
regulation of epithelial cell proliferation GO:0050678 49 0.021
negative regulation of cell development GO:0010721 82 0.020
Rat
hormone transport GO:0009914 121 0.020
positive regulation of programmed cell death GO:0043068 157 0.020
peptidyl amino acid modification GO:0018193 126 0.020
sensory perception of pain GO:0019233 73 0.020
regulation of nucleic acid templated transcription GO:1903506 380 0.020
epithelial cell proliferation GO:0050673 54 0.020
positive regulation of cell differentiation GO:0045597 217 0.020
Rat
neuropeptide signaling pathway GO:0007218 29 0.020
ossification GO:0001503 70 0.020
organ morphogenesis GO:0009887 75 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.019
response to retinoic acid GO:0032526 63 0.019
negative regulation of response to stimulus GO:0048585 155 0.019
Rat
positive regulation of secretion GO:0051047 140 0.019
negative regulation of macromolecule metabolic process GO:0010605 260 0.019
regulation of stem cell differentiation GO:2000736 2 0.019
localization of cell GO:0051674 202 0.019
response to toxic substance GO:0009636 133 0.019
glial cell differentiation GO:0010001 65 0.019
Rat
multi multicellular organism process GO:0044706 138 0.018
cardiac chamber development GO:0003205 1 0.018
lipid transport GO:0006869 61 0.018
negative regulation of neuron death GO:1901215 69 0.018
actin cytoskeleton organization GO:0030036 73 0.018
modified amino acid transport GO:0072337 12 0.018
cellular calcium ion homeostasis GO:0006874 160 0.018
neuron differentiation GO:0030182 368 0.018
Rat
response to reactive oxygen species GO:0000302 120 0.018
neuronal action potential GO:0019228 35 0.017
response to ammonium ion GO:0060359 71 0.017
hormone secretion GO:0046879 115 0.017
regulation of erk1 and erk2 cascade GO:0070372 41 0.017
transmembrane transport GO:0055085 412 0.017
nitrogen compound transport GO:0071705 229 0.017
response to insulin GO:0032868 133 0.017
response to monosaccharide GO:0034284 159 0.017
cytoplasmic transport GO:0016482 115 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.017
protein phosphorylation GO:0006468 345 0.017
chemosensory behavior GO:0007635 2 0.017
alpha amino acid metabolic process GO:1901605 71 0.017
regulation of defecation GO:2000292 1 0.017
response to cgmp GO:0070305 3 0.017
peptide hormone secretion GO:0030072 84 0.017
hormone metabolic process GO:0042445 69 0.017
muscle contraction GO:0006936 88 0.016
regulation of synaptic transmission GO:0050804 141 0.016
cell morphogenesis GO:0000902 142 0.016
female sex differentiation GO:0046660 59 0.016
organonitrogen compound biosynthetic process GO:1901566 167 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
cognition GO:0050890 92 0.016
aging GO:0007568 241 0.016
exocytosis GO:0006887 60 0.016
sex differentiation GO:0007548 113 0.016
Rat
synaptic growth at neuromuscular junction GO:0051124 1 0.016
cellular response to cgmp GO:0071321 2 0.016
lipid biosynthetic process GO:0008610 128 0.016
macromolecule localization GO:0033036 252 0.016
cellular amino acid metabolic process GO:0006520 107 0.015
cell junction organization GO:0034330 21 0.015
spindle organization GO:0007051 2 0.015
response to calcium ion GO:0051592 59 0.015
male gamete generation GO:0048232 99 0.015
Rat
negative regulation of apoptotic process GO:0043066 181 0.015
circulatory system process GO:0003013 183 0.015
heart process GO:0003015 57 0.015
negative regulation of neurogenesis GO:0050768 78 0.015
Rat
response to transition metal nanoparticle GO:1990267 122 0.015
embryo development GO:0009790 49 0.015
gastric motility GO:0035482 3 0.015
protein complex assembly GO:0006461 263 0.015
signal release GO:0023061 145 0.015
neuron fate commitment GO:0048663 4 0.015
biological adhesion GO:0022610 110 0.015
sequestering of calcium ion GO:0051208 8 0.015
regulation of programmed cell death GO:0043067 341 0.015
heart morphogenesis GO:0003007 3 0.015
maintenance of location GO:0051235 17 0.015
regulation of protein modification process GO:0031399 194 0.015
regulation of transferase activity GO:0051338 123 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
neuron projection development GO:0031175 273 0.015
regulation of cell motility GO:2000145 131 0.014
positive regulation of protein modification process GO:0031401 142 0.014
positive regulation of transferase activity GO:0051347 81 0.014
cellular response to hexose stimulus GO:0071331 65 0.014
divalent inorganic cation homeostasis GO:0072507 165 0.014
ribonucleotide metabolic process GO:0009259 231 0.014
metal ion homeostasis GO:0055065 186 0.014
negative regulation of cell proliferation GO:0008285 119 0.014
neuron development GO:0048666 286 0.014
regulation of molecular function GO:0065009 398 0.014
ensheathment of neurons GO:0007272 40 0.014
cell type specific apoptotic process GO:0097285 134 0.014
positive regulation of molecular function GO:0044093 230 0.014
protein oligomerization GO:0051259 191 0.014
wound healing GO:0042060 122 0.014
amine metabolic process GO:0009308 38 0.014
monocarboxylic acid transport GO:0015718 52 0.014
organic acid metabolic process GO:0006082 292 0.014
regulation of ion homeostasis GO:2000021 63 0.014
myelination GO:0042552 39 0.014
cellular component morphogenesis GO:0032989 155 0.014
positive regulation of epithelial cell proliferation GO:0050679 32 0.013
response to hexose GO:0009746 144 0.013
regulation of vesicle mediated transport GO:0060627 81 0.013
regulation of purine nucleotide metabolic process GO:1900542 115 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.013
regulation of growth GO:0040008 105 0.013
positive regulation of serotonin secretion GO:0014064 1 0.013
cell projection organization GO:0030030 302 0.013
forebrain development GO:0030900 98 0.013
regulation of system process GO:0044057 208 0.013
gonad development GO:0008406 104 0.013
Rat
regulation of membrane potential GO:0042391 110 0.013
cellular response to glucocorticoid stimulus GO:0071385 68 0.013
cell migration GO:0016477 197 0.013
nucleoside phosphate biosynthetic process GO:1901293 102 0.013
sequestering of metal ion GO:0051238 9 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.013
mechanoreceptor differentiation GO:0042490 2 0.013
Rat
homeostatic process GO:0042592 331 0.013
blood circulation GO:0008015 183 0.013
negative regulation of phosphate metabolic process GO:0045936 80 0.013
hormone biosynthetic process GO:0042446 25 0.013
regulation of smooth muscle cell proliferation GO:0048660 75 0.013
olfactory learning GO:0008355 1 0.012
cellular response to corticosteroid stimulus GO:0071384 69 0.012
response to glucose GO:0009749 136 0.012
odontogenesis GO:0042476 32 0.012
leukocyte differentiation GO:0002521 30 0.012
activation of protein kinase activity GO:0032147 47 0.012
secretion by cell GO:0032940 248 0.012
cellular amine metabolic process GO:0044106 38 0.012
respiratory tube development GO:0030323 43 0.012
head development GO:0060322 247 0.012
Rat
negative regulation of hormone secretion GO:0046888 46 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
regulation of blood pressure GO:0008217 83 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
regulation of blood circulation GO:1903522 110 0.012
cell adhesion GO:0007155 110 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
negative regulation of synaptic transmission dopaminergic GO:0032227 4 0.011
ion homeostasis GO:0050801 212 0.011
response to decreased oxygen levels GO:0036293 237 0.011
Rat
organic hydroxy compound transport GO:0015850 77 0.011
calcium ion homeostasis GO:0055074 162 0.011
insulin secretion GO:0030073 69 0.011
epithelial cell differentiation GO:0030855 71 0.011
Rat
catabolic process GO:0009056 351 0.011
negative regulation of defecation GO:2000293 1 0.011
positive regulation of cell development GO:0010720 176 0.011
Rat
regulation of cell projection organization GO:0031344 175 0.011
tube development GO:0035295 89 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.011
carbohydrate homeostasis GO:0033500 75 0.011
developmental process involved in reproduction GO:0003006 159 0.011
Rat
cellular response to stress GO:0033554 269 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.011
bmp signaling pathway GO:0030509 4 0.011
regulation of defense response GO:0031347 68 0.011
sex determination GO:0007530 2 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
organic hydroxy compound biosynthetic process GO:1901617 51 0.011
mitotic spindle organization GO:0007052 2 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
muscle cell proliferation GO:0033002 84 0.011
developmental maturation GO:0021700 25 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
response to fatty acid GO:0070542 65 0.011
protein localization GO:0008104 191 0.011
vasoconstriction GO:0042310 54 0.010
cellular response to mechanical stimulus GO:0071260 48 0.010
positive regulation of immune system process GO:0002684 90 0.010
receptor mediated endocytosis GO:0006898 42 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
cellular homeostasis GO:0019725 252 0.010
response to vitamin GO:0033273 131 0.010
synaptic transmission GO:0007268 235 0.010
dna metabolic process GO:0006259 96 0.010
organic acid transport GO:0015849 116 0.010
cellular response to glucagon stimulus GO:0071377 7 0.010
negative regulation of gene expression GO:0010629 199 0.010
enzyme linked receptor protein signaling pathway GO:0007167 116 0.010
nucleobase containing compound catabolic process GO:0034655 152 0.010
regulation of hormone secretion GO:0046883 106 0.010
response to isoquinoline alkaloid GO:0014072 28 0.010
regulation of intracellular transport GO:0032386 65 0.010
negative regulation of innate immune response GO:0045824 4 0.010
response to molecule of bacterial origin GO:0002237 194 0.010
regulation of cellular component biogenesis GO:0044087 86 0.010
negative regulation of amine transport GO:0051953 24 0.010
negative regulation of follicle stimulating hormone secretion GO:0046882 3 0.010

Dlk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 0 0.020
disease of anatomical entity DOID:7 0 0.020
connective tissue disease DOID:65 0 0.020