Rattus norvegicus

14 known processes

Dmrt1

doublesex and mab-3 related transcription factor 1

Dmrt1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to endogenous stimulus GO:0071495 377 0.405
tissue development GO:0009888 252 0.292
regulation of multicellular organismal development GO:2000026 376 0.190
neuron differentiation GO:0030182 368 0.159
response to external biotic stimulus GO:0043207 221 0.125
response to estrogen GO:0043627 232 0.122
negative regulation of cell death GO:0060548 229 0.110
nucleic acid templated transcription GO:0097659 379 0.101
regulation of cell proliferation GO:0042127 359 0.099
regulation of cell differentiation GO:0045595 320 0.092
regulation of programmed cell death GO:0043067 341 0.087
negative regulation of multicellular organismal process GO:0051241 203 0.084
negative regulation of cell proliferation GO:0008285 119 0.083
regulation of neurogenesis GO:0050767 247 0.082
sodium ion transport GO:0006814 82 0.082
rhythmic process GO:0048511 156 0.082
response to decreased oxygen levels GO:0036293 237 0.074
negative regulation of rna metabolic process GO:0051253 123 0.072
transcription dna templated GO:0006351 377 0.071
regulation of cellular component organization GO:0051128 368 0.070
regulation of rna biosynthetic process GO:2001141 381 0.066
regulation of apoptotic process GO:0042981 335 0.065
regeneration GO:0031099 163 0.064
regulation of nervous system development GO:0051960 264 0.061
neurological system process GO:0050877 219 0.061
response to reactive oxygen species GO:0000302 120 0.061
immune system process GO:0002376 204 0.061
regulation of membrane potential GO:0042391 110 0.059
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.058
positive regulation of cellular component organization GO:0051130 200 0.058
regulation of nucleic acid templated transcription GO:1903506 380 0.058
rna metabolic process GO:0016070 406 0.057
cellular response to stress GO:0033554 269 0.056
regulation of cell development GO:0060284 263 0.055
negative regulation of developmental process GO:0051093 125 0.053
positive regulation of programmed cell death GO:0043068 157 0.052
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.052
homeostatic process GO:0042592 331 0.052
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.051
regulation of transcription dna templated GO:0006355 374 0.051
regulation of system process GO:0044057 208 0.049
cellular protein localization GO:0034613 122 0.049
reproductive system development GO:0061458 128 0.048
amine metabolic process GO:0009308 38 0.048
programmed cell death GO:0012501 392 0.047
response to oxygen levels GO:0070482 265 0.047
intracellular signal transduction GO:0035556 314 0.047
cellular catabolic process GO:0044248 295 0.047
positive regulation of biosynthetic process GO:0009891 319 0.047
response to extracellular stimulus GO:0009991 380 0.046
positive regulation of multicellular organismal process GO:0051240 387 0.046
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.046
anatomical structure morphogenesis GO:0009653 298 0.046
central nervous system development GO:0007417 311 0.045
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.045
response to wounding GO:0009611 254 0.044
negative regulation of response to stimulus GO:0048585 155 0.044
rna biosynthetic process GO:0032774 380 0.043
positive regulation of molecular function GO:0044093 230 0.043
neuron development GO:0048666 286 0.043
locomotion GO:0040011 237 0.042
circulatory system process GO:0003013 183 0.041
response to nutrient levels GO:0031667 370 0.041
intracellular transport GO:0046907 185 0.040
multicellular organism reproduction GO:0032504 233 0.040
negative regulation of macromolecule metabolic process GO:0010605 260 0.039
cellular component assembly GO:0022607 360 0.038
cell morphogenesis GO:0000902 142 0.038
heart morphogenesis GO:0003007 3 0.038
neuron neuron synaptic transmission GO:0007270 60 0.036
positive regulation of cell development GO:0010720 176 0.036
organ regeneration GO:0031100 101 0.036
growth GO:0040007 165 0.036
cell morphogenesis involved in differentiation GO:0000904 119 0.035
positive regulation of apoptotic process GO:0043065 154 0.035
protein transport GO:0015031 132 0.034
positive regulation of cell proliferation GO:0008284 249 0.034
ovulation cycle GO:0042698 67 0.034
muscle tissue development GO:0060537 58 0.034
developmental growth GO:0048589 100 0.033
membrane organization GO:0061024 94 0.033
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.033
regulation of catalytic activity GO:0050790 304 0.033
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.032
head development GO:0060322 247 0.032
cellular amine metabolic process GO:0044106 38 0.032
anion transmembrane transport GO:0098656 77 0.032
biological adhesion GO:0022610 110 0.031
positive regulation of cell communication GO:0010647 271 0.031
response to other organism GO:0051707 220 0.030
positive regulation of gene expression GO:0010628 244 0.030
brain development GO:0007420 247 0.030
cognition GO:0050890 92 0.030
single organism organelle organization GO:1902589 180 0.029
cellular response to hormone stimulus GO:0032870 247 0.029
reproductive structure development GO:0048608 128 0.029
positive regulation of nervous system development GO:0051962 178 0.029
positive regulation of cell death GO:0010942 184 0.028
regulation of rna metabolic process GO:0051252 391 0.028
blood vessel morphogenesis GO:0048514 58 0.028
synaptic transmission GO:0007268 235 0.028
development of primary sexual characteristics GO:0045137 107 0.028
response to toxic substance GO:0009636 133 0.028
regulation of neuron differentiation GO:0045664 208 0.028
response to ketone GO:1901654 182 0.028
phospholipid metabolic process GO:0006644 61 0.027
cell cell signaling GO:0007267 335 0.027
organic acid transport GO:0015849 116 0.027
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.027
response to carbohydrate GO:0009743 183 0.026
negative regulation of gene expression GO:0010629 199 0.026
transcription from rna polymerase ii promoter GO:0006366 252 0.026
cellular homeostasis GO:0019725 252 0.026
positive regulation of nucleic acid templated transcription GO:1903508 197 0.026
secretion GO:0046903 307 0.026
negative regulation of cell differentiation GO:0045596 99 0.026
positive regulation of cell differentiation GO:0045597 217 0.025
striated muscle tissue development GO:0014706 58 0.025
cytoplasmic transport GO:0016482 115 0.025
synapse organization GO:0050808 46 0.025
positive regulation of signal transduction GO:0009967 175 0.025
response to biotic stimulus GO:0009607 226 0.025
positive regulation of rna metabolic process GO:0051254 203 0.024
apoptotic process GO:0006915 381 0.024
detection of temperature stimulus GO:0016048 4 0.024
metal ion transport GO:0030001 289 0.024
negative regulation of metabolic process GO:0009892 331 0.024
negative regulation of cellular metabolic process GO:0031324 281 0.024
cell motility GO:0048870 202 0.024
single organism intracellular transport GO:1902582 166 0.024
positive regulation of catalytic activity GO:0043085 184 0.024
sex differentiation GO:0007548 113 0.024
negative regulation of cellular biosynthetic process GO:0031327 161 0.024
positive regulation of protein modification process GO:0031401 142 0.024
regulation of cell migration GO:0030334 128 0.024
cellular ion homeostasis GO:0006873 184 0.024
developmental process involved in reproduction GO:0003006 159 0.023
negative regulation of programmed cell death GO:0043069 183 0.023
embryonic cranial skeleton morphogenesis GO:0048701 2 0.023
positive regulation of cellular amine metabolic process GO:0033240 3 0.023
localization of cell GO:0051674 202 0.023
cellular component movement GO:0006928 248 0.022
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.022
reproductive process GO:0022414 372 0.022
cellular amino acid metabolic process GO:0006520 107 0.022
sensory organ development GO:0007423 74 0.022
regulation of cellular localization GO:0060341 263 0.022
organ growth GO:0035265 24 0.022
muscle structure development GO:0061061 87 0.022
cellular response to oxygen containing compound GO:1901701 386 0.022
anion transport GO:0006820 178 0.022
negative regulation of transcription dna templated GO:0045892 116 0.021
development of primary female sexual characteristics GO:0046545 56 0.021
response to nutrient GO:0007584 248 0.021
protein oligomerization GO:0051259 191 0.021
organ morphogenesis GO:0009887 75 0.021
positive regulation of developmental process GO:0051094 283 0.020
hematopoietic progenitor cell differentiation GO:0002244 2 0.020
protein phosphorylation GO:0006468 345 0.020
enzyme linked receptor protein signaling pathway GO:0007167 116 0.020
regulation of ion homeostasis GO:2000021 63 0.019
positive regulation of phosphorus metabolic process GO:0010562 262 0.019
cellular response to growth factor stimulus GO:0071363 162 0.019
regulation of molecular function GO:0065009 398 0.019
cellular component biogenesis GO:0044085 368 0.019
protein localization GO:0008104 191 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
action potential GO:0001508 54 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
endocrine process GO:0050886 32 0.019
activation of protein kinase activity GO:0032147 47 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
mitotic spindle organization GO:0007052 2 0.018
female pregnancy GO:0007565 122 0.018
positive regulation of cell motility GO:2000147 97 0.018
response to purine containing compound GO:0014074 126 0.018
gliogenesis GO:0042063 93 0.018
positive regulation of neurogenesis GO:0050769 165 0.018
regulation of homotypic cell cell adhesion GO:0034110 4 0.018
response to hypoxia GO:0001666 231 0.018
single organism reproductive process GO:0044702 297 0.018
regulation of signal transduction GO:0009966 318 0.018
response to growth factor GO:0070848 189 0.018
response to transition metal nanoparticle GO:1990267 122 0.018
cellular divalent inorganic cation homeostasis GO:0072503 162 0.018
response to organophosphorus GO:0046683 102 0.017
neuron death GO:0070997 127 0.017
muscle system process GO:0003012 115 0.017
cell growth GO:0016049 104 0.017
cell projection organization GO:0030030 302 0.017
positive regulation of rna biosynthetic process GO:1902680 197 0.017
gastrulation GO:0007369 2 0.017
single organism cell adhesion GO:0098602 46 0.017
regulation of transferase activity GO:0051338 123 0.017
response to estradiol GO:0032355 164 0.017
negative regulation of biosynthetic process GO:0009890 168 0.017
retina development in camera type eye GO:0060041 27 0.017
regulation of protein metabolic process GO:0051246 289 0.017
limbic system development GO:0021761 38 0.017
female gonad development GO:0008585 53 0.016
reproduction GO:0000003 245 0.016
cytosolic calcium ion homeostasis GO:0051480 140 0.016
circulatory system development GO:0072359 134 0.016
ion homeostasis GO:0050801 212 0.016
response to retinoic acid GO:0032526 63 0.016
regulation of growth GO:0040008 105 0.016
cardiac muscle contraction GO:0060048 27 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.016
negative regulation of rna biosynthetic process GO:1902679 118 0.016
cation transport GO:0006812 382 0.016
cell activation GO:0001775 97 0.016
muscle cell proliferation GO:0033002 84 0.016
negative regulation of cell communication GO:0010648 158 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
cell cycle GO:0007049 101 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
embryo development GO:0009790 49 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
gonad development GO:0008406 104 0.016
tube development GO:0035295 89 0.016
transmission of nerve impulse GO:0019226 42 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
vesicle mediated transport GO:0016192 181 0.016
intracellular protein transport GO:0006886 79 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.015
muscle tissue morphogenesis GO:0060415 1 0.015
regulation of kinase activity GO:0043549 117 0.015
response to camp GO:0051591 91 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.015
mapk cascade GO:0000165 140 0.015
positive regulation of fibroblast proliferation GO:0048146 15 0.015
microtubule based process GO:0007017 36 0.015
negative regulation of nervous system development GO:0051961 79 0.015
cell adhesion GO:0007155 110 0.015
regulation of blood pressure GO:0008217 83 0.015
chemical homeostasis GO:0048878 292 0.015
organelle organization GO:0006996 266 0.015
embryonic skeletal system morphogenesis GO:0048704 3 0.015
olfactory behavior GO:0042048 2 0.014
cardiac muscle tissue development GO:0048738 26 0.014
blood circulation GO:0008015 183 0.014
multicellular organismal homeostasis GO:0048871 49 0.014
response to ethanol GO:0045471 162 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.014
negative regulation of signal transduction GO:0009968 83 0.014
response to inorganic substance GO:0010035 377 0.014
ossification GO:0001503 70 0.014
cellular ketone metabolic process GO:0042180 51 0.014
cardiac muscle tissue growth GO:0055017 20 0.014
regulation of phosphate metabolic process GO:0019220 349 0.014
muscle contraction GO:0006936 88 0.014
regulation of systemic arterial blood pressure by norepinephrine epinephrine GO:0001993 2 0.014
ovulation cycle process GO:0022602 50 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
sequestering of metal ion GO:0051238 9 0.013
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.013
proteolysis GO:0006508 175 0.013
response to fatty acid GO:0070542 65 0.013
cardiovascular system development GO:0072358 134 0.013
forebrain development GO:0030900 98 0.013
wnt signaling pathway GO:0016055 17 0.013
metal ion homeostasis GO:0055065 186 0.013
calcium ion homeostasis GO:0055074 162 0.013
cardiac chamber development GO:0003205 1 0.013
spindle organization GO:0007051 2 0.013
protein complex assembly GO:0006461 263 0.013
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.013
response to radiation GO:0009314 137 0.013
regulation of synaptic plasticity GO:0048167 70 0.013
response to lipopolysaccharide GO:0032496 191 0.013
single organism behavior GO:0044708 130 0.013
response to temperature stimulus GO:0009266 94 0.013
smooth muscle contraction GO:0006939 37 0.013
urinary bladder smooth muscle contraction GO:0014832 4 0.013
regulation of blood circulation GO:1903522 110 0.013
regulation of cellular ketone metabolic process GO:0010565 27 0.013
positive regulation of cell migration GO:0030335 96 0.013
negative regulation of epithelial cell proliferation GO:0050680 16 0.013
response to hyperoxia GO:0055093 45 0.012
urogenital system development GO:0001655 78 0.012
response to bacterium GO:0009617 200 0.012
inflammatory response GO:0006954 150 0.012
regulation of hydrolase activity GO:0051336 143 0.012
organonitrogen compound biosynthetic process GO:1901566 167 0.012
cellular macromolecule localization GO:0070727 122 0.012
regulation of stem cell differentiation GO:2000736 2 0.012
positive regulation of cellular biosynthetic process GO:0031328 295 0.012
neuron projection development GO:0031175 273 0.012
regulation of protein maturation GO:1903317 50 0.012
glial cell differentiation GO:0010001 65 0.012
multi multicellular organism process GO:0044706 138 0.012
embryonic skeletal system development GO:0048706 3 0.012
regulation of phosphorylation GO:0042325 248 0.012
t cell tolerance induction GO:0002517 3 0.012
regulation of smooth muscle contraction GO:0006940 29 0.012
neuron projection morphogenesis GO:0048812 122 0.012
secretion by cell GO:0032940 248 0.012
palate development GO:0060021 2 0.012
positive regulation of transport GO:0051050 245 0.012
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.012
regulation of defense response GO:0031347 68 0.012
sequestering of calcium ion GO:0051208 8 0.012
signal release GO:0023061 145 0.012
regulation of cell adhesion GO:0030155 52 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
regulation of systemic arterial blood pressure GO:0003073 30 0.012
regulation of response to external stimulus GO:0032101 106 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.011
regulation of intracellular signal transduction GO:1902531 218 0.011
regulation of organelle organization GO:0033043 80 0.011
regulation of secretion by cell GO:1903530 208 0.011
positive regulation of phosphate metabolic process GO:0045937 262 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
negative regulation of signaling GO:0023057 157 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
glycosaminoglycan biosynthetic process GO:0006024 4 0.011
nucleoside catabolic process GO:0009164 126 0.011
catabolic process GO:0009056 351 0.011
gland development GO:0048732 155 0.011
heart development GO:0007507 72 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
defense response GO:0006952 194 0.011
positive regulation of epithelial cell proliferation GO:0050679 32 0.011
ras protein signal transduction GO:0007265 29 0.011
neuron fate commitment GO:0048663 4 0.011
response to gonadotropin GO:0034698 34 0.011
regulation of cellular component movement GO:0051270 150 0.011
negative regulation of neurogenesis GO:0050768 78 0.011
regulation of response to wounding GO:1903034 69 0.011
nucleobase containing small molecule metabolic process GO:0055086 316 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
autophagic cell death GO:0048102 4 0.011
regulation of neuron apoptotic process GO:0043523 83 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
regulation of synaptic transmission GO:0050804 141 0.011
organophosphate catabolic process GO:0046434 148 0.011
salivary gland development GO:0007431 3 0.011
multi organism reproductive process GO:0044703 262 0.011
bmp signaling pathway GO:0030509 4 0.011
hormone metabolic process GO:0042445 69 0.010
inner ear development GO:0048839 21 0.010
macromolecule localization GO:0033036 252 0.010
saliva secretion GO:0046541 3 0.010
organophosphate metabolic process GO:0019637 370 0.010
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.010
regulation of cellular protein metabolic process GO:0032268 267 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
anterior posterior pattern specification GO:0009952 1 0.010
cation homeostasis GO:0055080 195 0.010
macromolecular complex assembly GO:0065003 273 0.010
aging GO:0007568 241 0.010
camera type eye development GO:0043010 48 0.010
male sex differentiation GO:0046661 64 0.010

Dmrt1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.056
nervous system disease DOID:863 0 0.056
sensory system disease DOID:0050155 0 0.028
cardiovascular system disease DOID:1287 0 0.013
disease of cellular proliferation DOID:14566 0 0.011