Rattus norvegicus

29 known processes

Dnase1

deoxyribonuclease I

(Aliases: MGC108543)

Dnase1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
linoleic acid metabolic process GO:0043651 4 0.486
positive regulation of transport GO:0051050 245 0.481
oxoacid metabolic process GO:0043436 290 0.343
carboxylic acid metabolic process GO:0019752 289 0.295
regulation of peptide hormone secretion GO:0090276 80 0.263
organic acid metabolic process GO:0006082 292 0.240
regulation of hormone levels GO:0010817 187 0.239
response to inorganic substance GO:0010035 377 0.199
hormone transport GO:0009914 121 0.197
positive regulation of peptide secretion GO:0002793 52 0.180
response to biotic stimulus GO:0009607 226 0.180
regulation of blood circulation GO:1903522 110 0.178
transcription from rna polymerase ii promoter GO:0006366 252 0.172
regulation of rna metabolic process GO:0051252 391 0.155
negative regulation of cellular biosynthetic process GO:0031327 161 0.148
positive regulation of secretion GO:0051047 140 0.144
catabolic process GO:0009056 351 0.144
chemical homeostasis GO:0048878 292 0.140
nitrogen compound transport GO:0071705 229 0.134
regulation of peptide secretion GO:0002791 82 0.131
homeostatic process GO:0042592 331 0.122
cellular ketone metabolic process GO:0042180 51 0.113
central nervous system development GO:0007417 311 0.112
regulation of rna biosynthetic process GO:2001141 381 0.109
blood circulation GO:0008015 183 0.108
response to external biotic stimulus GO:0043207 221 0.103
regulation of cellular ketone metabolic process GO:0010565 27 0.102
single organism biosynthetic process GO:0044711 342 0.101
transmembrane transport GO:0055085 412 0.101
positive regulation of immunoglobulin production GO:0002639 4 0.100
regulation of secretion GO:0051046 224 0.100
response to glucocorticoid GO:0051384 223 0.098
rna metabolic process GO:0016070 406 0.097
circulatory system process GO:0003013 183 0.097
response to metal ion GO:0010038 253 0.091
positive regulation of peptide hormone secretion GO:0090277 50 0.090
transcription dna templated GO:0006351 377 0.089
regulation of peptide transport GO:0090087 87 0.088
response to bacterium GO:0009617 200 0.086
unsaturated fatty acid metabolic process GO:0033559 39 0.086
monocarboxylic acid metabolic process GO:0032787 152 0.086
neurological system process GO:0050877 219 0.084
cellular catabolic process GO:0044248 295 0.080
cation homeostasis GO:0055080 195 0.080
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.079
cellular response to oxygen containing compound GO:1901701 386 0.076
positive regulation of insulin secretion GO:0032024 36 0.076
protein complex assembly GO:0006461 263 0.075
regulation of transcription dna templated GO:0006355 374 0.071
ion homeostasis GO:0050801 212 0.071
rna biosynthetic process GO:0032774 380 0.070
cellular chemical homeostasis GO:0055082 247 0.067
cellular homeostasis GO:0019725 252 0.065
negative regulation of nucleic acid templated transcription GO:1903507 117 0.064
amide transport GO:0042886 105 0.063
cell cell signaling GO:0007267 335 0.061
response to alkaloid GO:0043279 132 0.061
macromolecular complex subunit organization GO:0043933 339 0.060
odontogenesis GO:0042476 32 0.059
regulation of blood pressure GO:0008217 83 0.059
response to other organism GO:0051707 220 0.058
cellular response to stress GO:0033554 269 0.058
response to nutrient levels GO:0031667 370 0.057
secretion GO:0046903 307 0.057
ion transmembrane transport GO:0034220 365 0.057
response to monosaccharide GO:0034284 159 0.057
nucleic acid templated transcription GO:0097659 379 0.056
regulation of hormone secretion GO:0046883 106 0.056
positive regulation of hormone secretion GO:0046887 65 0.055
organic anion transport GO:0015711 132 0.054
pyruvate metabolic process GO:0006090 27 0.053
vitamin d receptor signaling pathway GO:0070561 1 0.053
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.053
steroid biosynthetic process GO:0006694 48 0.051
purine ribonucleoside metabolic process GO:0046128 168 0.051
vitamin d metabolic process GO:0042359 4 0.050
regulation of multicellular organismal development GO:2000026 376 0.050
protein complex subunit organization GO:0071822 302 0.050
cytosolic calcium ion homeostasis GO:0051480 140 0.050
response to cytokine GO:0034097 215 0.049
regulation of anion transport GO:0044070 43 0.049
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.048
organic acid biosynthetic process GO:0016053 83 0.048
regulation of catabolic process GO:0009894 113 0.047
negative regulation of cell communication GO:0010648 158 0.047
response to oxygen levels GO:0070482 265 0.046
heart morphogenesis GO:0003007 3 0.046
cellular response to lipid GO:0071396 201 0.046
regulation of secretion by cell GO:1903530 208 0.046
response to peptide hormone GO:0043434 278 0.046
positive regulation of rna biosynthetic process GO:1902680 197 0.046
response to decreased oxygen levels GO:0036293 237 0.045
regulation of insulin secretion GO:0050796 65 0.045
organic acid transport GO:0015849 116 0.044
single organism catabolic process GO:0044712 283 0.044
negative regulation of transcription dna templated GO:0045892 116 0.044
positive regulation of cell communication GO:0010647 271 0.043
cation transport GO:0006812 382 0.042
cellular response to organic cyclic compound GO:0071407 202 0.042
cellular response to hormone stimulus GO:0032870 247 0.041
insulin secretion GO:0030073 69 0.041
regulation of ion transport GO:0043269 245 0.041
regulation of tube size GO:0035150 89 0.041
response to osmotic stress GO:0006970 42 0.041
multi organism reproductive process GO:0044703 262 0.041
regulation of immunoglobulin production GO:0002637 4 0.040
regulation of nucleic acid templated transcription GO:1903506 380 0.039
regeneration GO:0031099 163 0.039
kidney development GO:0001822 67 0.039
organ regeneration GO:0031100 101 0.039
positive regulation of blood circulation GO:1903524 65 0.039
response to ketone GO:1901654 182 0.038
aromatic compound catabolic process GO:0019439 168 0.038
positive regulation of multicellular organismal process GO:0051240 387 0.038
protein complex biogenesis GO:0070271 263 0.038
organic substance catabolic process GO:1901575 316 0.038
peptide secretion GO:0002790 86 0.037
peptide hormone secretion GO:0030072 84 0.037
hormone metabolic process GO:0042445 69 0.037
anion transport GO:0006820 178 0.037
anatomical structure morphogenesis GO:0009653 298 0.036
positive regulation of gene expression GO:0010628 244 0.036
heterocycle catabolic process GO:0046700 167 0.036
potassium ion transmembrane transport GO:0071805 71 0.035
response to purine containing compound GO:0014074 126 0.035
negative regulation of rna biosynthetic process GO:1902679 118 0.035
nucleobase containing small molecule metabolic process GO:0055086 316 0.035
carbohydrate derivative metabolic process GO:1901135 346 0.035
peptide transport GO:0015833 97 0.035
regulation of norepinephrine secretion GO:0014061 15 0.035
response to peptide GO:1901652 292 0.035
negative regulation of cardiac muscle tissue growth GO:0055022 3 0.035
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.035
macromolecular complex assembly GO:0065003 273 0.034
positive regulation of defense response GO:0031349 37 0.034
cellular calcium ion homeostasis GO:0006874 160 0.034
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.034
negative regulation of collagen biosynthetic process GO:0032966 4 0.033
cellular response to glucocorticoid stimulus GO:0071385 68 0.033
cellular cation homeostasis GO:0030003 180 0.033
response to corticosteroid GO:0031960 235 0.033
negative regulation of metabolic process GO:0009892 331 0.033
negative regulation of signaling GO:0023057 157 0.033
response to hexose GO:0009746 144 0.033
nucleoside phosphate metabolic process GO:0006753 283 0.032
lipid biosynthetic process GO:0008610 128 0.032
response to extracellular stimulus GO:0009991 380 0.032
metal ion homeostasis GO:0055065 186 0.032
hormone secretion GO:0046879 115 0.032
response to acid chemical GO:0001101 222 0.032
c21 steroid hormone biosynthetic process GO:0006700 10 0.031
regulation of blood vessel size GO:0050880 89 0.031
defense response GO:0006952 194 0.031
sensory perception GO:0007600 101 0.031
response to estrogen GO:0043627 232 0.030
positive regulation of cellular biosynthetic process GO:0031328 295 0.030
response to oxidative stress GO:0006979 186 0.030
reproductive process GO:0022414 372 0.030
anterior posterior pattern specification GO:0009952 1 0.029
regulation of cellular amine metabolic process GO:0033238 8 0.029
vasoconstriction GO:0042310 54 0.029
positive regulation of transcription dna templated GO:0045893 197 0.029
response to glucose GO:0009749 136 0.029
muscle cell proliferation GO:0033002 84 0.028
potassium ion transport GO:0006813 97 0.028
cellular metal ion homeostasis GO:0006875 172 0.028
negative regulation of cellular metabolic process GO:0031324 281 0.028
regulation of response to stress GO:0080134 126 0.028
regulation of cell differentiation GO:0045595 320 0.028
positive regulation of phosphate metabolic process GO:0045937 262 0.028
positive regulation of signaling GO:0023056 270 0.027
positive regulation of secretion by cell GO:1903532 128 0.027
multi multicellular organism process GO:0044706 138 0.027
monovalent inorganic cation transport GO:0015672 172 0.027
neuron differentiation GO:0030182 368 0.027
cellular response to vitamin e GO:0071306 3 0.027
response to vitamin GO:0033273 131 0.027
response to starvation GO:0042594 59 0.027
organ formation GO:0048645 3 0.027
cellular amine metabolic process GO:0044106 38 0.026
regulation of protein phosphorylation GO:0001932 183 0.026
carbohydrate homeostasis GO:0033500 75 0.026
negative regulation of cardiac muscle tissue development GO:0055026 3 0.026
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
metal ion transport GO:0030001 289 0.026
carboxylic acid transport GO:0046942 115 0.026
positive regulation of phosphorus metabolic process GO:0010562 262 0.026
inorganic cation transmembrane transport GO:0098662 202 0.025
amine metabolic process GO:0009308 38 0.025
cellular component biogenesis GO:0044085 368 0.025
digestive system development GO:0055123 41 0.025
positive regulation of developmental process GO:0051094 283 0.024
reproduction GO:0000003 245 0.024
fatty acid metabolic process GO:0006631 99 0.024
regulation of cellular localization GO:0060341 263 0.024
response to amino acid GO:0043200 75 0.024
cell motility GO:0048870 202 0.024
regulation of catalytic activity GO:0050790 304 0.024
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.024
vascular process in circulatory system GO:0003018 96 0.023
fat soluble vitamin biosynthetic process GO:0042362 2 0.023
synaptic transmission glutamatergic GO:0035249 33 0.023
carbohydrate metabolic process GO:0005975 130 0.023
regulation of anatomical structure size GO:0090066 135 0.023
regulation of system process GO:0044057 208 0.023
negative regulation of programmed cell death GO:0043069 183 0.023
heart development GO:0007507 72 0.023
behavior GO:0007610 205 0.023
reproductive system development GO:0061458 128 0.023
cell communication by chemical coupling GO:0010643 2 0.022
hexose transport GO:0008645 29 0.022
head development GO:0060322 247 0.022
regulation of programmed cell death GO:0043067 341 0.022
negative regulation of gene expression GO:0010629 199 0.022
antibiotic transport GO:0042891 2 0.022
positive regulation of rna metabolic process GO:0051254 203 0.022
positive regulation of norepinephrine secretion GO:0010701 4 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.021
purine containing compound metabolic process GO:0072521 253 0.021
digestive tract development GO:0048565 39 0.021
positive regulation of ion transport GO:0043270 94 0.021
positive regulation of cell proliferation GO:0008284 249 0.021
acid secretion GO:0046717 48 0.021
response to carbohydrate GO:0009743 183 0.021
cofactor metabolic process GO:0051186 95 0.021
positive regulation of nucleic acid templated transcription GO:1903508 197 0.021
muscle system process GO:0003012 115 0.020
cardiovascular system development GO:0072358 134 0.020
response to lipopolysaccharide GO:0032496 191 0.020
negative regulation of multicellular organismal process GO:0051241 203 0.020
regulation of signal transduction GO:0009966 318 0.020
negative regulation of organ growth GO:0046621 3 0.020
neuromuscular process GO:0050905 2 0.020
brain development GO:0007420 247 0.020
negative regulation of rna metabolic process GO:0051253 123 0.020
response to insulin GO:0032868 133 0.020
aging GO:0007568 241 0.019
ribonucleotide catabolic process GO:0009261 136 0.019
programmed cell death GO:0012501 392 0.019
cellular response to cytokine stimulus GO:0071345 127 0.019
negative regulation of cell proliferation GO:0008285 119 0.019
excretion GO:0007588 24 0.019
purine ribonucleotide metabolic process GO:0009150 227 0.019
positive regulation of phagocytosis engulfment GO:0060100 4 0.019
g protein coupled receptor signaling pathway GO:0007186 242 0.019
nucleotide metabolic process GO:0009117 279 0.019
regulation of pancreatic stellate cell proliferation GO:2000229 2 0.019
angiogenesis GO:0001525 53 0.019
carboxylic acid biosynthetic process GO:0046394 83 0.018
small molecule biosynthetic process GO:0044283 124 0.018
regulation of phagocytosis engulfment GO:0060099 4 0.018
response to fatty acid GO:0070542 65 0.018
organophosphate metabolic process GO:0019637 370 0.018
lipid storage GO:0019915 1 0.018
vasculature development GO:0001944 70 0.018
cellular response to carbohydrate stimulus GO:0071322 72 0.018
regulation of systemic arterial blood pressure GO:0003073 30 0.018
divalent inorganic cation homeostasis GO:0072507 165 0.017
regulation of cell proliferation GO:0042127 359 0.017
signal release GO:0023061 145 0.017
apoptotic process GO:0006915 381 0.017
calcitriol biosynthetic process from calciol GO:0036378 2 0.017
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.017
cation transmembrane transport GO:0098655 263 0.017
sexual reproduction GO:0019953 148 0.017
negative regulation of macromolecule metabolic process GO:0010605 260 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
pancreatic stellate cell proliferation GO:0072343 2 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.017
monosaccharide transport GO:0015749 31 0.016
monoamine transport GO:0015844 43 0.016
cellular amino acid metabolic process GO:0006520 107 0.016
response to nutrient GO:0007584 248 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
regulation of dna metabolic process GO:0051052 60 0.016
regulation of phosphorus metabolic process GO:0051174 349 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
regulation of protein metabolic process GO:0051246 289 0.016
cardiac chamber development GO:0003205 1 0.016
glycosyl compound metabolic process GO:1901657 182 0.016
cellular response to abiotic stimulus GO:0071214 85 0.016
purine nucleotide metabolic process GO:0006163 229 0.016
regulation of phosphorylation GO:0042325 248 0.016
ribonucleoside metabolic process GO:0009119 174 0.016
gliogenesis GO:0042063 93 0.016
insecticide metabolic process GO:0017143 4 0.015
negative regulation of apoptotic process GO:0043066 181 0.015
icosanoid biosynthetic process GO:0046456 18 0.015
positive regulation of molecular function GO:0044093 230 0.015
response to testosterone GO:0033574 55 0.015
muscle tissue development GO:0060537 58 0.015
cellular response to peptide GO:1901653 133 0.015
fatty acid derivative metabolic process GO:1901568 38 0.015
exogenous drug catabolic process GO:0042738 1 0.015
glucose homeostasis GO:0042593 75 0.015
response to pain GO:0048265 11 0.015
response to wounding GO:0009611 254 0.015
cellular response to corticosteroid stimulus GO:0071384 69 0.015
locomotion GO:0040011 237 0.015
growth GO:0040007 165 0.014
membrane organization GO:0061024 94 0.014
icosanoid metabolic process GO:0006690 38 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
neural crest cell differentiation GO:0014033 2 0.014
glutamate secretion GO:0014047 19 0.014
cellular component assembly GO:0022607 360 0.014
anatomical structure formation involved in morphogenesis GO:0048646 83 0.014
regulation of defense response GO:0031347 68 0.014
negative regulation of biosynthetic process GO:0009890 168 0.014
regulation of body fluid levels GO:0050878 90 0.014
multicellular organism reproduction GO:0032504 233 0.014
cellular ion homeostasis GO:0006873 184 0.014
progesterone metabolic process GO:0042448 8 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
mesoderm development GO:0007498 2 0.014
organic hydroxy compound transport GO:0015850 77 0.014
epithelium development GO:0060429 96 0.014
regulation of cellular component movement GO:0051270 150 0.014
negative regulation of transcription regulatory region dna binding GO:2000678 2 0.014
positive regulation of biosynthetic process GO:0009891 319 0.014
positive regulation of catabolic process GO:0009896 78 0.014
exploration behavior GO:0035640 1 0.013
multicellular organismal reproductive process GO:0048609 233 0.013
regulation of cellular protein metabolic process GO:0032268 267 0.013
regulation of mononuclear cell proliferation GO:0032944 26 0.013
amino acid transport GO:0006865 70 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
androgen biosynthetic process GO:0006702 10 0.013
regulation of organic acid transport GO:0032890 35 0.013
mapk cascade GO:0000165 140 0.013
regulation of apoptotic process GO:0042981 335 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
tetrapyrrole metabolic process GO:0033013 11 0.013
regulation of calcium ion transport GO:0051924 77 0.013
cellular response to peptide hormone stimulus GO:0071375 120 0.013
negative regulation of transport GO:0051051 136 0.013
positive regulation of homeostatic process GO:0032846 49 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
organic cyclic compound catabolic process GO:1901361 175 0.013
inflammatory response GO:0006954 150 0.013
monocarboxylic acid biosynthetic process GO:0072330 48 0.013
cellular response to prostaglandin stimulus GO:0071379 7 0.013
response to fluid shear stress GO:0034405 16 0.013
response to interleukin 1 GO:0070555 55 0.013
cellular protein complex assembly GO:0043623 44 0.013
organic hydroxy compound metabolic process GO:1901615 115 0.012
cellular macromolecular complex assembly GO:0034622 58 0.012
fatty acid biosynthetic process GO:0006633 33 0.012
regulation of transcription regulatory region dna binding GO:2000677 4 0.012
positive regulation of protein modification process GO:0031401 142 0.012
protein oligomerization GO:0051259 191 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
regulation of cell motility GO:2000145 131 0.012
response to temperature stimulus GO:0009266 94 0.012
protein phosphorylation GO:0006468 345 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
carbohydrate biosynthetic process GO:0016051 42 0.012
cellular response to inorganic substance GO:0071241 65 0.012
regulation of ion homeostasis GO:2000021 63 0.012
renal system development GO:0072001 67 0.012
negative regulation of pancreatic stellate cell proliferation GO:2000230 1 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
nucleoside catabolic process GO:0009164 126 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.012
toxin transport GO:1901998 3 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.012
cofactor biosynthetic process GO:0051188 28 0.011
cellular response to hexose stimulus GO:0071331 65 0.011
positive regulation of calcium ion transport GO:0051928 36 0.011
nucleoside metabolic process GO:0009116 179 0.011
smooth muscle cell proliferation GO:0048659 77 0.011
steroid metabolic process GO:0008202 73 0.011
nucleotide catabolic process GO:0009166 139 0.011
estrogen biosynthetic process GO:0006703 6 0.011
regulation of lymphocyte proliferation GO:0050670 26 0.011
lipid metabolic process GO:0006629 283 0.011
positive regulation of cell differentiation GO:0045597 217 0.011
cellular potassium ion transport GO:0071804 72 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
negative regulation of collagen metabolic process GO:0010713 4 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 12 0.011
alcohol biosynthetic process GO:0046165 38 0.011
response to nicotine GO:0035094 51 0.011
cellular macromolecule localization GO:0070727 122 0.011
formation of primary germ layer GO:0001704 1 0.011
cell projection organization GO:0030030 302 0.011
embryo development GO:0009790 49 0.010
choline transport GO:0015871 4 0.010
vasodilation GO:0042311 44 0.010
regulation of ion transmembrane transport GO:0034765 121 0.010
regulation of nervous system development GO:0051960 264 0.010
negative regulation of phosphate metabolic process GO:0045936 80 0.010
regulation of metal ion transport GO:0010959 118 0.010
vitamin d biosynthetic process GO:0042368 2 0.010
chordate embryonic development GO:0043009 18 0.010
regulation of vasodilation GO:0042312 36 0.010
regulation of cell activation GO:0050865 50 0.010
behavioral response to nicotine GO:0035095 2 0.010
positive regulation of immunoglobulin mediated immune response GO:0002891 2 0.010
response to fungicide GO:0060992 20 0.010
heart process GO:0003015 57 0.010
cellular glucose homeostasis GO:0001678 66 0.010
cellular response to tumor necrosis factor GO:0071356 46 0.010
negative regulation of cardiac muscle cell proliferation GO:0060044 2 0.010
rho protein signal transduction GO:0007266 11 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
macromolecule localization GO:0033036 252 0.010
negative regulation of heart growth GO:0061117 3 0.010
negative regulation of multicellular organismal metabolic process GO:0044252 4 0.010
positive regulation of apoptotic process GO:0043065 154 0.010
odontogenesis of dentin containing tooth GO:0042475 18 0.010
regulation of purine nucleotide metabolic process GO:1900542 115 0.010
intracellular signal transduction GO:0035556 314 0.010
purine nucleoside triphosphate catabolic process GO:0009146 122 0.010

Dnase1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.048
disease of anatomical entity DOID:7 0 0.044
Human
urinary system disease DOID:18 0 0.044
kidney disease DOID:557 0 0.028
inherited metabolic disorder DOID:655 0 0.027
nervous system disease DOID:863 0 0.024
sensory system disease DOID:0050155 0 0.010