Rattus norvegicus

62 known processes

Doc2b

double C2-like domains, beta

Doc2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
behavior GO:0007610 205 0.287
regulation of muscle system process GO:0090257 79 0.253
cell cell signaling GO:0007267 335 0.222
transmembrane transport GO:0055085 412 0.181
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.166
positive regulation of cell differentiation GO:0045597 217 0.162
regulation of neuron differentiation GO:0045664 208 0.152
organic acid metabolic process GO:0006082 292 0.131
glycosyl compound metabolic process GO:1901657 182 0.129
cellular response to endogenous stimulus GO:0071495 377 0.126
secretion by cell GO:0032940 248 0.106
neuron differentiation GO:0030182 368 0.103
oxoacid metabolic process GO:0043436 290 0.102
cellular response to corticosteroid stimulus GO:0071384 69 0.095
inorganic ion transmembrane transport GO:0098660 229 0.092
regulation of multicellular organismal development GO:2000026 376 0.091
catabolic process GO:0009056 351 0.090
head development GO:0060322 247 0.085
neuron projection development GO:0031175 273 0.083
cellular response to oxygen containing compound GO:1901701 386 0.082
cellular response to organic cyclic compound GO:0071407 202 0.080
ion transmembrane transport GO:0034220 365 0.078
reproductive process GO:0022414 372 0.078
cellular response to lipid GO:0071396 201 0.077
nucleoside metabolic process GO:0009116 179 0.077
regulation of molecular function GO:0065009 398 0.077
positive regulation of developmental process GO:0051094 283 0.074
nucleobase containing small molecule metabolic process GO:0055086 316 0.074
regulation of cell proliferation GO:0042127 359 0.074
brain development GO:0007420 247 0.074
cellular nitrogen compound catabolic process GO:0044270 163 0.074
positive regulation of transport GO:0051050 245 0.072
positive regulation of neurogenesis GO:0050769 165 0.071
cellular homeostasis GO:0019725 252 0.071
regulation of rna metabolic process GO:0051252 391 0.070
response to growth factor GO:0070848 189 0.070
central nervous system development GO:0007417 311 0.070
regulation of ion transport GO:0043269 245 0.070
purine containing compound metabolic process GO:0072521 253 0.069
regulation of cellular localization GO:0060341 263 0.069
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.068
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.067
regulation of neurogenesis GO:0050767 247 0.067
response to corticosteroid GO:0031960 235 0.067
nucleotide catabolic process GO:0009166 139 0.066
developmental process involved in reproduction GO:0003006 159 0.066
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.066
carboxylic acid metabolic process GO:0019752 289 0.066
regulation of system process GO:0044057 208 0.065
carboxylic acid catabolic process GO:0046395 49 0.063
nucleoside phosphate metabolic process GO:0006753 283 0.063
regulation of nervous system development GO:0051960 264 0.063
vesicle mediated transport GO:0016192 181 0.061
positive regulation of neuron differentiation GO:0045666 126 0.060
response to carbohydrate GO:0009743 183 0.060
ribonucleotide metabolic process GO:0009259 231 0.060
response to nutrient levels GO:0031667 370 0.059
positive regulation of multicellular organismal process GO:0051240 387 0.059
muscle system process GO:0003012 115 0.058
regulation of cell differentiation GO:0045595 320 0.057
heterocycle catabolic process GO:0046700 167 0.057
synaptic transmission GO:0007268 235 0.057
positive regulation of nervous system development GO:0051962 178 0.056
organic acid catabolic process GO:0016054 49 0.055
organophosphate metabolic process GO:0019637 370 0.055
regulation of cell development GO:0060284 263 0.052
neuron development GO:0048666 286 0.052
regulation of rna biosynthetic process GO:2001141 381 0.052
regulation of secretion by cell GO:1903530 208 0.051
positive regulation of gene expression GO:0010628 244 0.049
purine nucleoside metabolic process GO:0042278 169 0.049
macromolecular complex subunit organization GO:0043933 339 0.049
purine nucleotide metabolic process GO:0006163 229 0.048
purine nucleotide catabolic process GO:0006195 136 0.048
signal release GO:0023061 145 0.048
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.047
transcription dna templated GO:0006351 377 0.047
positive regulation of rna biosynthetic process GO:1902680 197 0.046
ribonucleoside triphosphate catabolic process GO:0009203 122 0.046
rna metabolic process GO:0016070 406 0.045
cellular response to growth factor stimulus GO:0071363 162 0.045
aging GO:0007568 241 0.045
protein complex subunit organization GO:0071822 302 0.045
response to ammonium ion GO:0060359 71 0.045
cellular lipid metabolic process GO:0044255 208 0.044
nucleotide metabolic process GO:0009117 279 0.044
regulation of phosphorus metabolic process GO:0051174 349 0.044
carbohydrate derivative metabolic process GO:1901135 346 0.043
purine ribonucleotide metabolic process GO:0009150 227 0.043
metal ion transport GO:0030001 289 0.043
organophosphate biosynthetic process GO:0090407 143 0.042
cellular response to hormone stimulus GO:0032870 247 0.042
response to estrogen GO:0043627 232 0.042
cellular chemical homeostasis GO:0055082 247 0.042
response to toxic substance GO:0009636 133 0.041
ribonucleotide catabolic process GO:0009261 136 0.041
organonitrogen compound catabolic process GO:1901565 179 0.041
organic substance catabolic process GO:1901575 316 0.041
positive regulation of signaling GO:0023056 270 0.041
small molecule catabolic process GO:0044282 59 0.040
cellular catabolic process GO:0044248 295 0.040
organ morphogenesis GO:0009887 75 0.040
establishment of organelle localization GO:0051656 37 0.040
nitrogen compound transport GO:0071705 229 0.040
response to vitamin GO:0033273 131 0.039
regulation of phosphate metabolic process GO:0019220 349 0.039
anion transmembrane transport GO:0098656 77 0.039
regulation of catalytic activity GO:0050790 304 0.039
positive regulation of cell proliferation GO:0008284 249 0.038
organonitrogen compound biosynthetic process GO:1901566 167 0.038
neurological system process GO:0050877 219 0.037
positive regulation of molecular function GO:0044093 230 0.037
purine nucleoside triphosphate catabolic process GO:0009146 122 0.037
heart process GO:0003015 57 0.037
ribose phosphate metabolic process GO:0019693 235 0.036
positive regulation of cell development GO:0010720 176 0.036
rna biosynthetic process GO:0032774 380 0.036
regulation of neuron projection development GO:0010975 161 0.036
regulation of nucleic acid templated transcription GO:1903506 380 0.036
choline transport GO:0015871 4 0.036
organic cyclic compound catabolic process GO:1901361 175 0.035
g protein coupled receptor signaling pathway GO:0007186 242 0.034
secretion GO:0046903 307 0.034
potassium ion transport GO:0006813 97 0.033
positive regulation of cellular component organization GO:0051130 200 0.033
monovalent inorganic cation transport GO:0015672 172 0.033
purine ribonucleotide catabolic process GO:0009154 136 0.033
response to monosaccharide GO:0034284 159 0.033
circulatory system process GO:0003013 183 0.031
ribonucleoside metabolic process GO:0009119 174 0.031
response to peptide hormone GO:0043434 278 0.030
purine containing compound catabolic process GO:0072523 138 0.030
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.030
organic hydroxy compound metabolic process GO:1901615 115 0.030
ribonucleoside catabolic process GO:0042454 126 0.030
cell part morphogenesis GO:0032990 123 0.030
heart development GO:0007507 72 0.029
divalent inorganic cation homeostasis GO:0072507 165 0.028
cellular response to organonitrogen compound GO:0071417 197 0.028
regulation of nucleotide catabolic process GO:0030811 65 0.027
positive regulation of hydrolase activity GO:0051345 86 0.027
nucleoside catabolic process GO:0009164 126 0.027
regulation of muscle contraction GO:0006937 53 0.027
protein complex assembly GO:0006461 263 0.027
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.027
positive regulation of neuron projection development GO:0010976 99 0.027
oxidation reduction process GO:0055114 304 0.027
chemical homeostasis GO:0048878 292 0.027
purine nucleoside triphosphate metabolic process GO:0009144 141 0.026
homeostatic process GO:0042592 331 0.026
positive regulation of phosphate metabolic process GO:0045937 262 0.026
organ regeneration GO:0031100 101 0.026
single organism reproductive process GO:0044702 297 0.026
cellular divalent inorganic cation homeostasis GO:0072503 162 0.026
regulation of membrane potential GO:0042391 110 0.026
regulation of cell projection organization GO:0031344 175 0.026
glycosyl compound catabolic process GO:1901658 126 0.026
response to inorganic substance GO:0010035 377 0.026
single organism biosynthetic process GO:0044711 342 0.026
protein complex biogenesis GO:0070271 263 0.026
organic anion transport GO:0015711 132 0.025
cardiac chamber development GO:0003205 1 0.025
nucleobase containing compound catabolic process GO:0034655 152 0.025
regulation of cellular component organization GO:0051128 368 0.025
cell projection organization GO:0030030 302 0.025
purine ribonucleoside catabolic process GO:0046130 124 0.024
actin filament based process GO:0030029 86 0.024
inorganic cation transmembrane transport GO:0098662 202 0.024
negative regulation of metabolic process GO:0009892 331 0.024
protein homooligomerization GO:0051260 91 0.024
bmp signaling pathway GO:0030509 4 0.024
anion transport GO:0006820 178 0.024
circulatory system development GO:0072359 134 0.024
small molecule biosynthetic process GO:0044283 124 0.023
regulation of secretion GO:0051046 224 0.023
detection of visible light GO:0009584 3 0.023
rhythmic process GO:0048511 156 0.023
heart morphogenesis GO:0003007 3 0.023
positive regulation of cellular biosynthetic process GO:0031328 295 0.023
response to acid chemical GO:0001101 222 0.023
cardiovascular system development GO:0072358 134 0.022
dendrite development GO:0016358 72 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.022
aromatic compound catabolic process GO:0019439 168 0.022
anterior posterior pattern specification GO:0009952 1 0.022
cation transport GO:0006812 382 0.022
regulation of signal transduction GO:0009966 318 0.022
muscle contraction GO:0006936 88 0.021
response to extracellular stimulus GO:0009991 380 0.021
response to oxygen levels GO:0070482 265 0.021
cellular response to cytokine stimulus GO:0071345 127 0.021
positive regulation of transcription dna templated GO:0045893 197 0.021
response to uv c GO:0010225 2 0.020
multicellular organism reproduction GO:0032504 233 0.020
cell morphogenesis involved in differentiation GO:0000904 119 0.020
purine nucleoside catabolic process GO:0006152 124 0.020
calcium ion homeostasis GO:0055074 162 0.020
amino acid transport GO:0006865 70 0.020
positive regulation of cell communication GO:0010647 271 0.020
cation transmembrane transport GO:0098655 263 0.020
cell morphogenesis GO:0000902 142 0.019
cellular ion homeostasis GO:0006873 184 0.019
fatty acid metabolic process GO:0006631 99 0.019
regulation of cellular catabolic process GO:0031329 101 0.019
regulation of nucleotide metabolic process GO:0006140 117 0.019
regulation of potassium ion transport GO:0043266 29 0.019
phosphatidylinositol dephosphorylation GO:0046856 4 0.019
cellular response to glucocorticoid stimulus GO:0071385 68 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
response to glucocorticoid GO:0051384 223 0.019
cell projection morphogenesis GO:0048858 123 0.019
positive regulation of rna metabolic process GO:0051254 203 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.018
cellular amino acid biosynthetic process GO:0008652 32 0.018
protein transport GO:0015031 132 0.018
nucleic acid templated transcription GO:0097659 379 0.018
organophosphate catabolic process GO:0046434 148 0.018
regulation of programmed cell death GO:0043067 341 0.018
positive regulation of protein modification process GO:0031401 142 0.018
eye development GO:0001654 50 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.018
negative regulation of cellular component organization GO:0051129 83 0.018
positive regulation of protein metabolic process GO:0051247 178 0.018
action potential GO:0001508 54 0.018
response to hypoxia GO:0001666 231 0.017
positive regulation of cell projection organization GO:0031346 111 0.017
exocytosis GO:0006887 60 0.017
dna metabolic process GO:0006259 96 0.017
regulation of purine nucleotide metabolic process GO:1900542 115 0.017
response to insulin GO:0032868 133 0.017
positive regulation of ion transport GO:0043270 94 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.017
regulation of protein metabolic process GO:0051246 289 0.017
cellular calcium ion homeostasis GO:0006874 160 0.017
response to wounding GO:0009611 254 0.017
forebrain development GO:0030900 98 0.017
nucleoside triphosphate catabolic process GO:0009143 123 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.016
transcription from rna polymerase ii promoter GO:0006366 252 0.016
sex differentiation GO:0007548 113 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
ion homeostasis GO:0050801 212 0.016
regulation of hydrolase activity GO:0051336 143 0.016
regulation of dna metabolic process GO:0051052 60 0.016
positive regulation of biosynthetic process GO:0009891 319 0.016
vesicle organization GO:0016050 29 0.016
reproductive system development GO:0061458 128 0.016
metal ion homeostasis GO:0055065 186 0.016
telencephalon development GO:0021537 62 0.016
hematopoietic progenitor cell differentiation GO:0002244 2 0.016
fatty acid oxidation GO:0019395 29 0.016
glycerolipid metabolic process GO:0046486 67 0.015
cytoskeleton organization GO:0007010 111 0.015
cellular response to acid chemical GO:0071229 75 0.015
reproductive structure development GO:0048608 128 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
cellular amino acid metabolic process GO:0006520 107 0.015
apoptotic process GO:0006915 381 0.015
negative regulation of cell death GO:0060548 229 0.015
regulation of anatomical structure size GO:0090066 135 0.015
endocytosis GO:0006897 84 0.015
sodium ion transport GO:0006814 82 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
positive regulation of response to stimulus GO:0048584 285 0.015
cellular component morphogenesis GO:0032989 155 0.015
response to reactive oxygen species GO:0000302 120 0.015
positive regulation of secretion by cell GO:1903532 128 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
cellular amino acid catabolic process GO:0009063 21 0.015
ribonucleoside triphosphate metabolic process GO:0009199 141 0.015
gonad development GO:0008406 104 0.015
response to metal ion GO:0010038 253 0.014
positive regulation of signal transduction GO:0009967 175 0.014
cellular response to stress GO:0033554 269 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
cardiac ventricle development GO:0003231 1 0.014
purine nucleoside monophosphate metabolic process GO:0009126 84 0.014
response to other organism GO:0051707 220 0.014
anatomical structure morphogenesis GO:0009653 298 0.014
axon midline choice point recognition GO:0016199 2 0.014
guanosine containing compound metabolic process GO:1901068 74 0.014
synaptic vesicle localization GO:0097479 24 0.014
nucleoside monophosphate metabolic process GO:0009123 93 0.014
cellular component biogenesis GO:0044085 368 0.014
cardiac conduction GO:0061337 2 0.014
response to radiation GO:0009314 137 0.014
hormone transport GO:0009914 121 0.014
motor neuron axon guidance GO:0008045 1 0.014
asymmetric protein localization GO:0008105 2 0.014
cardiac muscle cell contraction GO:0086003 10 0.014
response to histamine GO:0034776 3 0.014
divalent inorganic cation transport GO:0072511 134 0.014
macromolecular complex assembly GO:0065003 273 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
dopamine transport GO:0015872 18 0.013
regulation of organelle organization GO:0033043 80 0.013
synaptic transmission glycinergic GO:0060012 2 0.013
cation homeostasis GO:0055080 195 0.013
regulation of g protein coupled receptor protein signaling pathway GO:0008277 28 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
regulation of ion transmembrane transport GO:0034765 121 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
regulation of response to stress GO:0080134 126 0.013
tissue development GO:0009888 252 0.013
protein phosphorylation GO:0006468 345 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
regulation of nucleoside metabolic process GO:0009118 66 0.013
regulation of cellular amino acid metabolic process GO:0006521 2 0.013
gtp metabolic process GO:0046039 72 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
positive regulation of catabolic process GO:0009896 78 0.012
response to dexamethasone GO:0071548 49 0.012
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
regulation of protein transport GO:0051223 68 0.012
axis specification GO:0009798 4 0.012
neuron projection morphogenesis GO:0048812 122 0.012
adult locomotory behavior GO:0008344 4 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
negative regulation of cell cycle phase transition GO:1901988 4 0.012
regulation of blood circulation GO:1903522 110 0.012
release of cytochrome c from mitochondria GO:0001836 8 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
macromolecule localization GO:0033036 252 0.012
response to oxidative stress GO:0006979 186 0.012
vesicle localization GO:0051648 33 0.012
organ formation GO:0048645 3 0.012
dorsal ventral axon guidance GO:0033563 1 0.012
regulation of neurotransmitter levels GO:0001505 42 0.012
neuromuscular synaptic transmission GO:0007274 2 0.012
alcohol metabolic process GO:0006066 77 0.012
immune response GO:0006955 104 0.012
positive regulation of nucleoside metabolic process GO:0045979 55 0.012
lipid metabolic process GO:0006629 283 0.012
sodium ion transmembrane transport GO:0035725 67 0.012
synaptic vesicle exocytosis GO:0016079 15 0.012
negative regulation of signaling GO:0023057 157 0.012
regulation of tube size GO:0035150 89 0.012
blood circulation GO:0008015 183 0.012
positive regulation of nucleic acid templated transcription GO:1903508 197 0.012
vascular process in circulatory system GO:0003018 96 0.011
amide transport GO:0042886 105 0.011
eye morphogenesis GO:0048592 4 0.011
gastrulation GO:0007369 2 0.011
response to fibroblast growth factor GO:0071774 29 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
multi organism reproductive process GO:0044703 262 0.011
catecholamine transport GO:0051937 37 0.011
sensory perception GO:0007600 101 0.011
embryonic pattern specification GO:0009880 1 0.011
cell cycle GO:0007049 101 0.011
cell communication involved in cardiac conduction GO:0086065 2 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
actin filament based movement GO:0030048 16 0.011
pallium development GO:0021543 42 0.011
cellular component maintenance GO:0043954 4 0.011
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
divalent metal ion transport GO:0070838 132 0.011
response to decreased oxygen levels GO:0036293 237 0.011
male gonad development GO:0008584 59 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
regulation of dendrite morphogenesis GO:0048814 33 0.010
negative regulation of macromolecule metabolic process GO:0010605 260 0.010
protein oligomerization GO:0051259 191 0.010
cellular modified amino acid biosynthetic process GO:0042398 18 0.010
exploration behavior GO:0035640 1 0.010
cellular ketone metabolic process GO:0042180 51 0.010
protein localization to organelle GO:0033365 57 0.010
regulation of transmembrane transport GO:0034762 122 0.010
cellular amine metabolic process GO:0044106 38 0.010
response to organophosphorus GO:0046683 102 0.010
sensory organ development GO:0007423 74 0.010
establishment of synaptic vesicle localization GO:0097480 23 0.010
tongue morphogenesis GO:0043587 3 0.010
response to nutrient GO:0007584 248 0.010
unsaturated fatty acid metabolic process GO:0033559 39 0.010

Doc2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.038
inherited metabolic disorder DOID:655 0 0.026
nervous system disease DOID:863 0 0.018
disease of anatomical entity DOID:7 0 0.018