Rattus norvegicus

54 known processes

Dpys

dihydropyrimidinase

Dpys biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
alpha amino acid metabolic process GO:1901605 71 0.749
halogenated hydrocarbon metabolic process GO:0042197 4 0.616
carboxylic acid metabolic process GO:0019752 289 0.614
chlorinated hydrocarbon metabolic process GO:0042196 4 0.559
organic acid catabolic process GO:0016054 49 0.471
oxoacid metabolic process GO:0043436 290 0.454
trichloroethylene metabolic process GO:0018979 1 0.431
response to cesium ion GO:0010164 2 0.425
epoxygenase p450 pathway GO:0019373 1 0.388
alkaloid metabolic process GO:0009820 3 0.378
cofactor metabolic process GO:0051186 95 0.322
nicotine metabolic process GO:0018933 1 0.243
phenylpropanoid metabolic process GO:0009698 5 0.235
organic acid biosynthetic process GO:0016053 83 0.219
protein complex biogenesis GO:0070271 263 0.218
fatty acid metabolic process GO:0006631 99 0.202
catabolic process GO:0009056 351 0.192
naphthalene containing compound metabolic process GO:0090420 2 0.180
aromatic amino acid family catabolic process GO:0009074 7 0.172
monocarboxylic acid metabolic process GO:0032787 152 0.171
organic acid metabolic process GO:0006082 292 0.169
catechol containing compound biosynthetic process GO:0009713 9 0.168
coenzyme metabolic process GO:0006732 86 0.167
carboxylic acid catabolic process GO:0046395 49 0.162
response to corticosteroid GO:0031960 235 0.151
cellular catabolic process GO:0044248 295 0.142
negative regulation of serine type endopeptidase activity GO:1900004 1 0.141
coumarin metabolic process GO:0009804 5 0.137
carboxylic acid biosynthetic process GO:0046394 83 0.136
liver development GO:0001889 90 0.135
catecholamine biosynthetic process GO:0042423 9 0.134
cellular amino acid metabolic process GO:0006520 107 0.131
response to xenobiotic stimulus GO:0009410 23 0.126
hepaticobiliary system development GO:0061008 90 0.123
small molecule catabolic process GO:0044282 59 0.121
single organism biosynthetic process GO:0044711 342 0.116
serine family amino acid metabolic process GO:0009069 12 0.114
glycine metabolic process GO:0006544 7 0.110
drug catabolic process GO:0042737 1 0.109
alpha amino acid catabolic process GO:1901606 20 0.106
neutral lipid metabolic process GO:0006638 21 0.100
alpha amino acid biosynthetic process GO:1901607 23 0.098
response to nicotine GO:0035094 51 0.093
cellular response to glucocorticoid stimulus GO:0071385 68 0.092
single organism catabolic process GO:0044712 283 0.091
regulation of cellular ketone metabolic process GO:0010565 27 0.088
sulfur compound metabolic process GO:0006790 70 0.087
hormone transport GO:0009914 121 0.086
cellular response to xenobiotic stimulus GO:0071466 19 0.085
heart morphogenesis GO:0003007 3 0.085
defecation GO:0030421 1 0.085
response to ethanol GO:0045471 162 0.084
cation transmembrane transport GO:0098655 263 0.083
response to sulfur dioxide GO:0010477 3 0.083
organonitrogen compound biosynthetic process GO:1901566 167 0.082
amine metabolic process GO:0009308 38 0.081
aromatic amino acid family metabolic process GO:0009072 9 0.080
pyridine containing compound metabolic process GO:0072524 32 0.080
unsaturated fatty acid metabolic process GO:0033559 39 0.071
ion homeostasis GO:0050801 212 0.071
cellular amino acid catabolic process GO:0009063 21 0.071
protein oligomerization GO:0051259 191 0.069
regulation of cellular localization GO:0060341 263 0.069
Rat
macromolecular complex assembly GO:0065003 273 0.069
response to inorganic substance GO:0010035 377 0.067
metal ion homeostasis GO:0055065 186 0.067
small molecule biosynthetic process GO:0044283 124 0.066
behavior GO:0007610 205 0.064
exogenous drug catabolic process GO:0042738 1 0.063
ion transmembrane transport GO:0034220 365 0.063
triglyceride metabolic process GO:0006641 21 0.062
drug metabolic process GO:0017144 11 0.062
cellular ion homeostasis GO:0006873 184 0.060
acylglycerol metabolic process GO:0006639 21 0.059
aromatic compound catabolic process GO:0019439 168 0.059
protein complex subunit organization GO:0071822 302 0.058
circulatory system process GO:0003013 183 0.057
phenol containing compound biosynthetic process GO:0046189 9 0.056
metal ion transport GO:0030001 289 0.056
cellular amine metabolic process GO:0044106 38 0.055
cation homeostasis GO:0055080 195 0.054
cellular metal ion homeostasis GO:0006875 172 0.054
cellular response to steroid hormone stimulus GO:0071383 93 0.054
cellular homeostasis GO:0019725 252 0.053
regulation of cellular component organization GO:0051128 368 0.052
Rat
indolalkylamine metabolic process GO:0006586 5 0.052
cellular chemical homeostasis GO:0055082 247 0.051
locomotion GO:0040011 237 0.051
Rat
circulatory system development GO:0072359 134 0.050
response to estrogen GO:0043627 232 0.050
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.048
cellular component assembly GO:0022607 360 0.047
response to metal ion GO:0010038 253 0.046
response to estradiol GO:0032355 164 0.046
single organism carbohydrate metabolic process GO:0044723 118 0.046
dopamine metabolic process GO:0042417 12 0.045
isoprenoid metabolic process GO:0006720 45 0.044
cell cell signaling GO:0007267 335 0.044
Rat
divalent inorganic cation transport GO:0072511 134 0.044
secretion GO:0046903 307 0.043
Rat
response to alkaloid GO:0043279 132 0.043
Rat
long chain fatty acid metabolic process GO:0001676 32 0.041
regulation of cellular amino acid metabolic process GO:0006521 2 0.041
response to insulin GO:0032868 133 0.041
arachidonic acid metabolic process GO:0019369 20 0.039
carbohydrate metabolic process GO:0005975 130 0.039
oligopeptide transport GO:0006857 4 0.039
thioester metabolic process GO:0035383 28 0.038
cellular cation homeostasis GO:0030003 180 0.038
protein complex assembly GO:0006461 263 0.038
regulation of extracellular matrix constituent secretion GO:0003330 2 0.038
catecholamine secretion GO:0050432 33 0.038
organic hydroxy compound biosynthetic process GO:1901617 51 0.038
lipid metabolic process GO:0006629 283 0.038
response to oxidative stress GO:0006979 186 0.037
regulation of multicellular organismal development GO:2000026 376 0.037
Rat
nitrogen compound transport GO:0071705 229 0.037
Rat
multi organism reproductive process GO:0044703 262 0.036
nucleoside phosphate metabolic process GO:0006753 283 0.036
cellular response to oxygen containing compound GO:1901701 386 0.035
response to peptide GO:1901652 292 0.035
organonitrogen compound catabolic process GO:1901565 179 0.034
response to acid chemical GO:0001101 222 0.034
antibiotic transport GO:0042891 2 0.034
glycogen metabolic process GO:0005977 23 0.033
naphthalene metabolic process GO:0018931 2 0.033
response to muscle activity involved in regulation of muscle adaptation GO:0014873 2 0.033
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.033
benzene containing compound metabolic process GO:0042537 22 0.031
cellular ketone metabolic process GO:0042180 51 0.031
response to camp GO:0051591 91 0.030
inorganic cation transmembrane transport GO:0098662 202 0.030
glutamine family amino acid metabolic process GO:0009064 15 0.030
organic substance catabolic process GO:1901575 316 0.030
glycerolipid metabolic process GO:0046486 67 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.029
serine family amino acid biosynthetic process GO:0009070 4 0.029
cation transport GO:0006812 382 0.029
chemical homeostasis GO:0048878 292 0.029
gland development GO:0048732 155 0.029
cognition GO:0050890 92 0.028
response to corticosterone GO:0051412 40 0.028
positive regulation of secretion by cell GO:1903532 128 0.028
Rat
negative regulation of metabolic process GO:0009892 331 0.028
reactive nitrogen species metabolic process GO:2001057 1 0.028
organic cyclic compound catabolic process GO:1901361 175 0.027
xenobiotic metabolic process GO:0006805 19 0.027
cellular lipid metabolic process GO:0044255 208 0.027
regulation of secretion GO:0051046 224 0.027
Rat
negative regulation of cellular metabolic process GO:0031324 281 0.027
regulation of ion transport GO:0043269 245 0.027
Rat
intracellular signal transduction GO:0035556 314 0.027
muscle cell differentiation GO:0042692 52 0.026
regulation of cellular amine metabolic process GO:0033238 8 0.026
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.026
organic hydroxy compound metabolic process GO:1901615 115 0.025
response to peptide hormone GO:0043434 278 0.025
cellular component biogenesis GO:0044085 368 0.024
negative regulation of macromolecule metabolic process GO:0010605 260 0.024
response to testosterone GO:0033574 55 0.024
dicarboxylic acid metabolic process GO:0043648 42 0.024
serine family amino acid catabolic process GO:0009071 3 0.024
organic hydroxy compound transport GO:0015850 77 0.023
acetyl coa metabolic process GO:0006084 17 0.023
carbohydrate derivative metabolic process GO:1901135 346 0.023
indole containing compound metabolic process GO:0042430 11 0.023
response to extracellular stimulus GO:0009991 380 0.023
icosanoid metabolic process GO:0006690 38 0.023
catechol containing compound metabolic process GO:0009712 19 0.022
homeostatic process GO:0042592 331 0.022
muscle system process GO:0003012 115 0.022
multi multicellular organism process GO:0044706 138 0.022
cellular divalent inorganic cation homeostasis GO:0072503 162 0.022
cell motility GO:0048870 202 0.022
Rat
anatomical structure morphogenesis GO:0009653 298 0.022
pancreatic stellate cell proliferation GO:0072343 2 0.022
response to mineralocorticoid GO:0051385 49 0.021
cellular modified amino acid metabolic process GO:0006575 61 0.021
oxidation reduction process GO:0055114 304 0.021
locomotory behavior GO:0007626 15 0.021
generation of precursor metabolites and energy GO:0006091 62 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
response to epidermal growth factor GO:0070849 18 0.021
positive regulation of multicellular organismal process GO:0051240 387 0.021
Rat
protein tetramerization GO:0051262 38 0.020
negative regulation of cellular protein metabolic process GO:0032269 106 0.020
catecholamine metabolic process GO:0006584 19 0.020
reproductive process GO:0022414 372 0.020
calcium ion homeostasis GO:0055074 162 0.020
organic anion transport GO:0015711 132 0.020
Rat
response to ketone GO:1901654 182 0.020
fatty acid derivative metabolic process GO:1901568 38 0.020
cellular response to alcohol GO:0097306 87 0.019
transmembrane transport GO:0055085 412 0.019
renal sodium excretion GO:0035812 20 0.019
angiotensin mediated drinking behavior GO:0003051 2 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
amide transport GO:0042886 105 0.019
regulation of serine type endopeptidase activity GO:1900003 1 0.019
response to chromate GO:0046687 3 0.019
calcium ion transport GO:0006816 131 0.019
bone development GO:0060348 25 0.018
heterocycle catabolic process GO:0046700 167 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
isoquinoline alkaloid metabolic process GO:0033076 2 0.018
aging GO:0007568 241 0.018
choline transport GO:0015871 4 0.018
response to zinc ion GO:0010043 39 0.018
positive regulation of ion transport GO:0043270 94 0.018
Rat
inflammatory response GO:0006954 150 0.018
establishment or maintenance of transmembrane electrochemical gradient GO:0010248 1 0.018
response to vitamin b6 GO:0034516 1 0.018
reactive oxygen species metabolic process GO:0072593 37 0.017
regulation of blood circulation GO:1903522 110 0.017
cellular amino acid biosynthetic process GO:0008652 32 0.017
regulation of excretion GO:0044062 21 0.017
response to triglyceride GO:0034014 3 0.017
neuron projection development GO:0031175 273 0.017
Rat
cellular response to oxidative stress GO:0034599 76 0.017
blood circulation GO:0008015 183 0.017
renin angiotensin regulation of aldosterone production GO:0002018 3 0.016
nucleobase containing small molecule metabolic process GO:0055086 316 0.016
response to decreased oxygen levels GO:0036293 237 0.016
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.016
regulation of transcription dna templated GO:0006355 374 0.016
response to prostaglandin f GO:0034696 4 0.016
response to growth factor GO:0070848 189 0.016
protein homotetramerization GO:0051289 25 0.015
glutathione transport GO:0034635 2 0.015
spermatogenesis GO:0007283 99 0.015
heart development GO:0007507 72 0.015
negative regulation of gene expression GO:0010629 199 0.015
monocarboxylic acid biosynthetic process GO:0072330 48 0.015
regulation of reactive oxygen species metabolic process GO:2000377 26 0.015
positive regulation of rna biosynthetic process GO:1902680 197 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
Rat
single organism behavior GO:0044708 130 0.015
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.015
negative regulation of molecular function GO:0044092 133 0.015
response to food GO:0032094 27 0.015
skeletal system development GO:0001501 41 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.015
cellular response to organic cyclic compound GO:0071407 202 0.015
pteridine containing compound metabolic process GO:0042558 14 0.015
cellular sodium ion homeostasis GO:0006883 4 0.015
lipid storage GO:0019915 1 0.014
cardiovascular system development GO:0072358 134 0.014
negative regulation of cell communication GO:0010648 158 0.014
synaptic transmission GO:0007268 235 0.014
Rat
organ regeneration GO:0031100 101 0.014
response to herbicide GO:0009635 16 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
regulation of systemic arterial blood pressure GO:0003073 30 0.014
phenol containing compound metabolic process GO:0018958 30 0.014
divalent metal ion transport GO:0070838 132 0.014
response to hypoxia GO:0001666 231 0.014
toxin transport GO:1901998 3 0.014
negative regulation of transport GO:0051051 136 0.014
cardiac chamber development GO:0003205 1 0.014
indolalkylamine catabolic process GO:0046218 5 0.014
nucleotide metabolic process GO:0009117 279 0.014
response to glucocorticoid GO:0051384 223 0.014
regulation of wound healing GO:0061041 14 0.014
monocarboxylic acid catabolic process GO:0072329 28 0.014
transcription from rna polymerase ii promoter GO:0006366 252 0.013
cellular component movement GO:0006928 248 0.013
Rat
positive regulation of molecular function GO:0044093 230 0.013
neurological system process GO:0050877 219 0.013
response to amphetamine GO:0001975 25 0.013
Rat
acyl coa metabolic process GO:0006637 28 0.013
cellular response to mechanical stimulus GO:0071260 48 0.013
actin filament based process GO:0030029 86 0.013
Rat
peptide secretion GO:0002790 86 0.013
response to radiation GO:0009314 137 0.013
positive regulation of biosynthetic process GO:0009891 319 0.013
retinoid metabolic process GO:0001523 24 0.013
pancreatic a cell differentiation GO:0003310 1 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
positive regulation of rna metabolic process GO:0051254 203 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
response to mechanical stimulus GO:0009612 134 0.013
carbohydrate biosynthetic process GO:0016051 42 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
Rat
neuron differentiation GO:0030182 368 0.012
Rat
regulation of peptide transport GO:0090087 87 0.012
tryptophan metabolic process GO:0006568 5 0.012
nucleic acid templated transcription GO:0097659 379 0.012
regulation of hormone levels GO:0010817 187 0.012
localization of cell GO:0051674 202 0.012
Rat
tripeptide transport GO:0042939 2 0.012
rna biosynthetic process GO:0032774 380 0.012
macromolecular complex subunit organization GO:0043933 339 0.012
cell projection organization GO:0030030 302 0.012
Rat
regulation of ion homeostasis GO:2000021 63 0.012
regulation of response to stress GO:0080134 126 0.012
regulation of hormone secretion GO:0046883 106 0.012
positive regulation of developmental process GO:0051094 283 0.012
Rat
regulation of protein phosphorylation GO:0001932 183 0.012
regulation of tube size GO:0035150 89 0.012
single organism intracellular transport GO:1902582 166 0.012
norepinephrine secretion GO:0048243 16 0.012
regulation of secretion by cell GO:1903530 208 0.012
Rat
diterpenoid metabolic process GO:0016101 33 0.012
cellular response to endogenous stimulus GO:0071495 377 0.012
gamete generation GO:0007276 124 0.012
positive regulation of cellular component organization GO:0051130 200 0.011
Rat
male gamete generation GO:0048232 99 0.011
catenin import into nucleus GO:0035411 1 0.011
catecholamine transport GO:0051937 37 0.011
growth GO:0040007 165 0.011
excretion GO:0007588 24 0.011
sodium ion homeostasis GO:0055078 23 0.011
striated muscle tissue development GO:0014706 58 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
Rat
regulation of anatomical structure size GO:0090066 135 0.011
insulin secretion GO:0030073 69 0.011
regulation of transferase activity GO:0051338 123 0.011
reproduction GO:0000003 245 0.011
regulation of body fluid levels GO:0050878 90 0.011
sulfur compound transport GO:0072348 8 0.011
brain renin angiotensin system GO:0002035 3 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.011
response to molecule of fungal origin GO:0002238 3 0.011
cholesterol homeostasis GO:0042632 3 0.011
protein phosphorylation GO:0006468 345 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
tryptophan catabolic process GO:0006569 5 0.011
protein homooligomerization GO:0051260 91 0.011
cellular response to lipid GO:0071396 201 0.011
amine catabolic process GO:0009310 9 0.011
response to wounding GO:0009611 254 0.011
Rat
defense response GO:0006952 194 0.011
positive regulation of cellular biosynthetic process GO:0031328 295 0.011
response to purine containing compound GO:0014074 126 0.011
brain development GO:0007420 247 0.010
Rat
regulation of blood vessel size GO:0050880 89 0.010
regulation of insulin secretion GO:0050796 65 0.010
sodium independent organic anion transport GO:0043252 2 0.010
secondary metabolic process GO:0019748 15 0.010
cellular macromolecular complex assembly GO:0034622 58 0.010
cellular nitrogen compound catabolic process GO:0044270 163 0.010
serotonin metabolic process GO:0042428 3 0.010
positive regulation of homeostatic process GO:0032846 49 0.010
secretion by cell GO:0032940 248 0.010
Rat
response to lead ion GO:0010288 33 0.010
regulation of catalytic activity GO:0050790 304 0.010
phenylpropanoid catabolic process GO:0046271 3 0.010
cellular response to peptide hormone stimulus GO:0071375 120 0.010
anion transport GO:0006820 178 0.010
Rat
muscle structure development GO:0061061 87 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
heart process GO:0003015 57 0.010
linoleic acid metabolic process GO:0043651 4 0.010
negative regulation of multicellular organismal process GO:0051241 203 0.010
Rat

Dpys disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
congenital hypothyroidism DOID:0050328 0 0.016
hypothyroidism DOID:1459 0 0.016
endocrine system disease DOID:28 0 0.016
disease of anatomical entity DOID:7 0 0.016
thyroid gland disease DOID:50 0 0.016
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011
disease of cellular proliferation DOID:14566 0 0.011