Rattus norvegicus

0 known processes

Efemp1

EGF-containing fibulin-like extracellular matrix protein 1

(Aliases: T16)

Efemp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
tissue development GO:0009888 252 0.281
Human
non canonical wnt signaling pathway GO:0035567 3 0.248
positive regulation of non canonical wnt signaling pathway GO:2000052 1 0.223
response to molecule of bacterial origin GO:0002237 194 0.191
wound healing GO:0042060 122 0.157
response to inorganic substance GO:0010035 377 0.151
negative regulation of cell death GO:0060548 229 0.148
cellular response to oxygen containing compound GO:1901701 386 0.140
immune system process GO:0002376 204 0.140
anatomical structure morphogenesis GO:0009653 298 0.137
rna biosynthetic process GO:0032774 380 0.136
Human
regulation of multicellular organismal development GO:2000026 376 0.136
Human
response to nutrient levels GO:0031667 370 0.135
regulation of rna metabolic process GO:0051252 391 0.134
Human
regulation of cell development GO:0060284 263 0.127
regulation of establishment of planar polarity GO:0090175 2 0.122
negative regulation of response to stimulus GO:0048585 155 0.120
response to wounding GO:0009611 254 0.115
regulation of cell proliferation GO:0042127 359 0.113
response to lipopolysaccharide GO:0032496 191 0.113
reproductive process GO:0022414 372 0.112
Rat
response to cytokine GO:0034097 215 0.109
muscle structure development GO:0061061 87 0.106
intracellular signal transduction GO:0035556 314 0.104
regulation of response to stress GO:0080134 126 0.099
regulation of protein metabolic process GO:0051246 289 0.099
response to metal ion GO:0010038 253 0.098
response to growth factor GO:0070848 189 0.093
response to oxidative stress GO:0006979 186 0.093
negative regulation of neurogenesis GO:0050768 78 0.090
cellular component movement GO:0006928 248 0.090
negative regulation of multicellular organismal process GO:0051241 203 0.090
Human
locomotion GO:0040011 237 0.088
Worm
cellular response to endogenous stimulus GO:0071495 377 0.083
response to corticosteroid GO:0031960 235 0.081
regulation of programmed cell death GO:0043067 341 0.081
negative regulation of signaling GO:0023057 157 0.079
organic acid metabolic process GO:0006082 292 0.079
regulation of neurogenesis GO:0050767 247 0.078
inflammatory response GO:0006954 150 0.077
transcription dna templated GO:0006351 377 0.076
Human
negative regulation of macromolecule metabolic process GO:0010605 260 0.075
regulation of molecular function GO:0065009 398 0.075
response to camp GO:0051591 91 0.072
response to external biotic stimulus GO:0043207 221 0.072
aging GO:0007568 241 0.071
regulation of apoptotic process GO:0042981 335 0.070
positive regulation of response to stimulus GO:0048584 285 0.070
negative regulation of cellular metabolic process GO:0031324 281 0.069
positive regulation of developmental process GO:0051094 283 0.066
regulation of body fluid levels GO:0050878 90 0.066
cell motility GO:0048870 202 0.066
regulation of nervous system development GO:0051960 264 0.065
cellular response to lipid GO:0071396 201 0.065
positive regulation of cell proliferation GO:0008284 249 0.064
response to nutrient GO:0007584 248 0.064
response to mechanical stimulus GO:0009612 134 0.062
positive regulation of cell differentiation GO:0045597 217 0.059
regulation of neuron differentiation GO:0045664 208 0.058
negative regulation of metabolic process GO:0009892 331 0.058
anatomical structure formation involved in morphogenesis GO:0048646 83 0.058
response to glucocorticoid GO:0051384 223 0.055
lipid transport GO:0006869 61 0.053
carboxylic acid metabolic process GO:0019752 289 0.053
transcription from rna polymerase ii promoter GO:0006366 252 0.053
negative regulation of cell development GO:0010721 82 0.052
cardiac chamber development GO:0003205 1 0.052
small molecule biosynthetic process GO:0044283 124 0.052
urogenital system development GO:0001655 78 0.051
positive regulation of immune system process GO:0002684 90 0.051
response to other organism GO:0051707 220 0.050
nucleic acid templated transcription GO:0097659 379 0.050
Human
single organism reproductive process GO:0044702 297 0.050
Rat
negative regulation of cell differentiation GO:0045596 99 0.050
Human
regulation of transcription dna templated GO:0006355 374 0.049
Human
regulation of cell motility GO:2000145 131 0.048
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.047
negative regulation of cell proliferation GO:0008285 119 0.046
apoptotic process GO:0006915 381 0.046
cellular ketone metabolic process GO:0042180 51 0.046
cell migration GO:0016477 197 0.045
regulation of phosphorylation GO:0042325 248 0.045
oxoacid metabolic process GO:0043436 290 0.045
cellular response to growth factor stimulus GO:0071363 162 0.044
regulation of cellular protein metabolic process GO:0032268 267 0.044
chemical homeostasis GO:0048878 292 0.043
regulation of phosphate metabolic process GO:0019220 349 0.042
response to radiation GO:0009314 137 0.041
protein phosphorylation GO:0006468 345 0.041
Human
cardiovascular system development GO:0072358 134 0.041
cell cell signaling GO:0007267 335 0.041
regulation of nucleic acid templated transcription GO:1903506 380 0.041
Human
positive regulation of phosphorylation GO:0042327 177 0.041
negative regulation of molecular function GO:0044092 133 0.041
ensheathment of neurons GO:0007272 40 0.041
negative regulation of gene expression GO:0010629 199 0.040
cellular response to cytokine stimulus GO:0071345 127 0.040
regulation of membrane potential GO:0042391 110 0.040
rna metabolic process GO:0016070 406 0.040
Human
regulation of cell differentiation GO:0045595 320 0.040
Human
action potential GO:0001508 54 0.039
central nervous system development GO:0007417 311 0.039
growth GO:0040007 165 0.038
regulation of phosphorus metabolic process GO:0051174 349 0.037
cation transport GO:0006812 382 0.037
response to estradiol GO:0032355 164 0.037
establishment of tissue polarity GO:0007164 2 0.037
lipid localization GO:0010876 62 0.037
negative regulation of programmed cell death GO:0043069 183 0.036
negative regulation of apoptotic process GO:0043066 181 0.036
programmed cell death GO:0012501 392 0.036
positive regulation of phosphate metabolic process GO:0045937 262 0.036
regeneration GO:0031099 163 0.036
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.036
negative regulation of organ growth GO:0046621 3 0.036
negative regulation of cell communication GO:0010648 158 0.036
acute inflammatory response GO:0002526 58 0.035
germ cell migration GO:0008354 1 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.035
multicellular organismal signaling GO:0035637 44 0.035
gland development GO:0048732 155 0.035
brain development GO:0007420 247 0.034
defense response GO:0006952 194 0.034
coagulation GO:0050817 28 0.033
organic acid biosynthetic process GO:0016053 83 0.033
regulation of catalytic activity GO:0050790 304 0.033
negative regulation of cardiac muscle tissue growth GO:0055022 3 0.033
negative regulation of signal transduction GO:0009968 83 0.033
response to glucose GO:0009749 136 0.033
regulation of hormone levels GO:0010817 187 0.032
cell activation GO:0001775 97 0.031
cellular component assembly GO:0022607 360 0.031
positive regulation of multicellular organismal process GO:0051240 387 0.031
myelination GO:0042552 39 0.031
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.031
neuronal action potential GO:0019228 35 0.030
positive regulation of cell death GO:0010942 184 0.030
regulation of rna biosynthetic process GO:2001141 381 0.030
Human
response to extracellular stimulus GO:0009991 380 0.030
muscle tissue development GO:0060537 58 0.030
cellular response to stress GO:0033554 269 0.029
positive regulation of signaling GO:0023056 270 0.029
regulation of cellular ketone metabolic process GO:0010565 27 0.029
organ regeneration GO:0031100 101 0.028
cellular homeostasis GO:0019725 252 0.028
regulation of canonical wnt signaling pathway GO:0060828 4 0.028
regulation of smooth muscle cell proliferation GO:0048660 75 0.028
blood coagulation GO:0007596 26 0.028
ventricular cardiac muscle cell action potential GO:0086005 2 0.028
regulation of system process GO:0044057 208 0.028
placenta development GO:0001890 22 0.027
neuron projection development GO:0031175 273 0.027
multi organism reproductive process GO:0044703 262 0.027
Rat
regulation of neuron projection development GO:0010975 161 0.027
immune response GO:0006955 104 0.027
female pregnancy GO:0007565 122 0.027
Rat
positive regulation of protein modification process GO:0031401 142 0.027
catabolic process GO:0009056 351 0.027
cell projection organization GO:0030030 302 0.026
carboxylic acid biosynthetic process GO:0046394 83 0.026
lipid metabolic process GO:0006629 283 0.026
reproductive structure development GO:0048608 128 0.026
regulation of protein modification process GO:0031399 194 0.026
hepaticobiliary system development GO:0061008 90 0.026
muscle organ development GO:0007517 50 0.026
organ morphogenesis GO:0009887 75 0.025
hormone metabolic process GO:0042445 69 0.025
head development GO:0060322 247 0.025
positive regulation of immune response GO:0050778 42 0.025
organophosphate metabolic process GO:0019637 370 0.025
localization of cell GO:0051674 202 0.025
gliogenesis GO:0042063 93 0.025
camera type eye morphogenesis GO:0048593 2 0.025
monovalent inorganic cation transport GO:0015672 172 0.024
tube development GO:0035295 89 0.024
homeostatic process GO:0042592 331 0.024
response to peptide GO:1901652 292 0.024
neurological system process GO:0050877 219 0.024
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.024
inorganic cation transmembrane transport GO:0098662 202 0.024
positive regulation of molecular function GO:0044093 230 0.024
transmission of nerve impulse GO:0019226 42 0.024
monocarboxylic acid metabolic process GO:0032787 152 0.024
regulation of cell projection organization GO:0031344 175 0.024
liver development GO:0001889 90 0.024
response to ionizing radiation GO:0010212 59 0.024
positive regulation of phosphorus metabolic process GO:0010562 262 0.024
positive regulation of cell development GO:0010720 176 0.023
response to peptide hormone GO:0043434 278 0.023
epithelium development GO:0060429 96 0.023
protein processing GO:0016485 68 0.023
blood vessel development GO:0001568 69 0.023
cellular response to molecule of bacterial origin GO:0071219 56 0.023
metal ion homeostasis GO:0055065 186 0.023
cellular chemical homeostasis GO:0055082 247 0.023
response to transition metal nanoparticle GO:1990267 122 0.023
kidney development GO:0001822 67 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.023
negative regulation of developmental process GO:0051093 125 0.023
Human
regulation of immune system process GO:0002682 123 0.023
hemostasis GO:0007599 26 0.023
regulation of immune response GO:0050776 55 0.022
vesicle mediated transport GO:0016192 181 0.022
multi multicellular organism process GO:0044706 138 0.022
Rat
positive regulation of neuron projection development GO:0010976 99 0.022
renal system development GO:0072001 67 0.022
cellular component biogenesis GO:0044085 368 0.022
striated muscle tissue development GO:0014706 58 0.022
neuron differentiation GO:0030182 368 0.021
peptidyl amino acid modification GO:0018193 126 0.021
Human
potassium ion transport GO:0006813 97 0.021
glial cell differentiation GO:0010001 65 0.021
positive regulation of protein metabolic process GO:0051247 178 0.021
taxis GO:0042330 67 0.021
cellular amine metabolic process GO:0044106 38 0.021
protein complex subunit organization GO:0071822 302 0.021
cellular amide metabolic process GO:0043603 44 0.020
eye morphogenesis GO:0048592 4 0.020
regulation of cellular component movement GO:0051270 150 0.020
positive regulation of gene expression GO:0010628 244 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
epithelial cell differentiation GO:0030855 71 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
regulation of cell growth GO:0001558 85 0.020
ion transmembrane transport GO:0034220 365 0.020
cardiac muscle cell action potential involved in contraction GO:0086002 2 0.020
tissue regeneration GO:0042246 36 0.019
response to ethanol GO:0045471 162 0.019
forebrain development GO:0030900 98 0.019
cellular amino acid metabolic process GO:0006520 107 0.019
axon ensheathment GO:0008366 40 0.019
amine metabolic process GO:0009308 38 0.019
metal ion transport GO:0030001 289 0.019
complement activation GO:0006956 11 0.019
coenzyme metabolic process GO:0006732 86 0.019
organic substance catabolic process GO:1901575 316 0.018
organonitrogen compound catabolic process GO:1901565 179 0.018
regulation of kinase activity GO:0043549 117 0.018
macromolecular complex subunit organization GO:0043933 339 0.018
cellular cation homeostasis GO:0030003 180 0.018
cellular response to organonitrogen compound GO:0071417 197 0.018
regulation of osteoblast differentiation GO:0045667 14 0.018
cellular ion homeostasis GO:0006873 184 0.018
response to hexose GO:0009746 144 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
inorganic ion transmembrane transport GO:0098660 229 0.018
multicellular organism reproduction GO:0032504 233 0.017
cation homeostasis GO:0055080 195 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.017
telencephalon development GO:0021537 62 0.017
regulation of protein phosphorylation GO:0001932 183 0.017
establishment of planar polarity GO:0001736 1 0.017
response to bacterium GO:0009617 200 0.017
negative regulation of biosynthetic process GO:0009890 168 0.017
negative regulation of transport GO:0051051 136 0.017
nucleotide metabolic process GO:0009117 279 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
estrous cycle phase GO:0060206 15 0.017
synaptic transmission GO:0007268 235 0.017
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.016
organic hydroxy compound transport GO:0015850 77 0.016
carbohydrate derivative metabolic process GO:1901135 346 0.016
divalent inorganic cation homeostasis GO:0072507 165 0.016
response to carbohydrate GO:0009743 183 0.016
regulation of apoptotic signaling pathway GO:2001233 13 0.016
negative regulation of cellular protein metabolic process GO:0032269 106 0.016
protein complex assembly GO:0006461 263 0.016
oxidation reduction process GO:0055114 304 0.016
response to organophosphorus GO:0046683 102 0.016
negative regulation of protein metabolic process GO:0051248 114 0.016
cellular catabolic process GO:0044248 295 0.016
regulation of growth GO:0040008 105 0.016
positive regulation of cellular component movement GO:0051272 102 0.016
immune effector process GO:0002252 53 0.016
circulatory system development GO:0072359 134 0.016
positive regulation of nervous system development GO:0051962 178 0.016
unsaturated fatty acid metabolic process GO:0033559 39 0.016
protein activation cascade GO:0072376 12 0.016
negative regulation of heart growth GO:0061117 3 0.016
transmembrane transport GO:0055085 412 0.016
response to alkaloid GO:0043279 132 0.015
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
morphogenesis of a polarized epithelium GO:0001738 1 0.015
cation transmembrane transport GO:0098655 263 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
immune response regulating signaling pathway GO:0002764 19 0.015
positive regulation of locomotion GO:0040017 102 0.015
Worm
response to vitamin GO:0033273 131 0.015
response to estrogen GO:0043627 232 0.015
sensory organ development GO:0007423 74 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.015
nucleoside phosphate metabolic process GO:0006753 283 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
positive regulation of catabolic process GO:0009896 78 0.015
regulation of locomotion GO:0040012 148 0.015
Worm
positive regulation of transport GO:0051050 245 0.015
cellular response to biotic stimulus GO:0071216 59 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
gastrulation GO:0007369 2 0.014
negative regulation of phosphorus metabolic process GO:0010563 80 0.014
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 1 0.014
potassium ion transmembrane transport GO:0071805 71 0.014
secretion GO:0046903 307 0.014
monocarboxylic acid biosynthetic process GO:0072330 48 0.014
negative regulation of neuron differentiation GO:0045665 62 0.014
ossification GO:0001503 70 0.014
activation of protein kinase activity GO:0032147 47 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
muscle system process GO:0003012 115 0.014
cellular response to steroid hormone stimulus GO:0071383 93 0.014
fatty acid derivative metabolic process GO:1901568 38 0.014
response to zinc ion GO:0010043 39 0.013
negative regulation of catalytic activity GO:0043086 103 0.013
cellular potassium ion transport GO:0071804 72 0.013
ion homeostasis GO:0050801 212 0.013
cell growth GO:0016049 104 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
positive regulation of biosynthetic process GO:0009891 319 0.013
oligodendrocyte differentiation GO:0048709 32 0.013
negative regulation of protein processing GO:0010955 47 0.013
inner ear receptor cell differentiation GO:0060113 2 0.013
protein complex biogenesis GO:0070271 263 0.013
response to monosaccharide GO:0034284 159 0.013
heart morphogenesis GO:0003007 3 0.013
dna metabolic process GO:0006259 96 0.013
single organism biosynthetic process GO:0044711 342 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
acid secretion GO:0046717 48 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
activation of immune response GO:0002253 26 0.013
cellular response to organic cyclic compound GO:0071407 202 0.013
regulation of potassium ion transport GO:0043266 29 0.013
regulation of signal transduction GO:0009966 318 0.012
endocytosis GO:0006897 84 0.012
secretion by cell GO:0032940 248 0.012
cellular response to acid chemical GO:0071229 75 0.012
single fertilization GO:0007338 3 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
organic hydroxy compound metabolic process GO:1901615 115 0.012
cellular response to oxidative stress GO:0034599 76 0.012
dna rewinding GO:0036292 1 0.012
positive regulation of cellular catabolic process GO:0031331 71 0.012
fatty acid metabolic process GO:0006631 99 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
fertilization GO:0009566 3 0.012
peptide transport GO:0015833 97 0.012
regulation of mapk cascade GO:0043408 116 0.012
hormone transport GO:0009914 121 0.012
cell type specific apoptotic process GO:0097285 134 0.012
negative regulation of nervous system development GO:0051961 79 0.012
cellular response to corticosteroid stimulus GO:0071384 69 0.011
regulation of cell migration GO:0030334 128 0.011
neuron development GO:0048666 286 0.011
mapk cascade GO:0000165 140 0.011
negative regulation of phosphate metabolic process GO:0045936 80 0.011
cellular response to hormone stimulus GO:0032870 247 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
regulation of secretion GO:0051046 224 0.011
amide transport GO:0042886 105 0.011
response to reactive oxygen species GO:0000302 120 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
smooth muscle cell proliferation GO:0048659 77 0.011
response to calcium ion GO:0051592 59 0.011
gonad development GO:0008406 104 0.010
male gamete generation GO:0048232 99 0.010
regulation of cellular response to stress GO:0080135 49 0.010
positive regulation of cell communication GO:0010647 271 0.010
macromolecular complex assembly GO:0065003 273 0.010
positive regulation of transferase activity GO:0051347 81 0.010
single organism intracellular transport GO:1902582 166 0.010
pyridine containing compound metabolic process GO:0072524 32 0.010
purine nucleotide metabolic process GO:0006163 229 0.010
positive regulation of programmed cell death GO:0043068 157 0.010
apoptotic signaling pathway GO:0097190 27 0.010
calcium ion homeostasis GO:0055074 162 0.010
response to acid chemical GO:0001101 222 0.010
response to purine containing compound GO:0014074 126 0.010

Efemp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
sensory system disease DOID:0050155 0 0.015
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
integumentary system disease DOID:16 0 0.011
gastrointestinal system disease DOID:77 0 0.011