Rattus norvegicus

0 known processes

Efemp2

EGF-containing fibulin-like extracellular matrix protein 2

(Aliases: MGC94840)

Efemp2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna biosynthetic process GO:0032774 380 0.147
regulation of nucleic acid templated transcription GO:1903506 380 0.132
regulation of cell differentiation GO:0045595 320 0.119
regulation of multicellular organismal development GO:2000026 376 0.118
nucleic acid templated transcription GO:0097659 379 0.111
negative regulation of macromolecule metabolic process GO:0010605 260 0.095
oxoacid metabolic process GO:0043436 290 0.091
regulation of rna metabolic process GO:0051252 391 0.080
ossification GO:0001503 70 0.068
rna metabolic process GO:0016070 406 0.068
negative regulation of cellular metabolic process GO:0031324 281 0.061
positive regulation of developmental process GO:0051094 283 0.059
regulation of rna biosynthetic process GO:2001141 381 0.059
cellular response to hormone stimulus GO:0032870 247 0.057
regulation of transcription dna templated GO:0006355 374 0.056
cellular response to oxygen containing compound GO:1901701 386 0.055
negative regulation of metabolic process GO:0009892 331 0.055
cellular response to endogenous stimulus GO:0071495 377 0.050
intracellular signal transduction GO:0035556 314 0.049
organic acid metabolic process GO:0006082 292 0.047
tissue development GO:0009888 252 0.046
regeneration GO:0031099 163 0.045
regulation of signal transduction GO:0009966 318 0.044
positive regulation of cell differentiation GO:0045597 217 0.044
transcription dna templated GO:0006351 377 0.044
positive regulation of response to stimulus GO:0048584 285 0.042
carboxylic acid metabolic process GO:0019752 289 0.038
growth GO:0040007 165 0.038
positive regulation of signal transduction GO:0009967 175 0.037
negative regulation of gene expression GO:0010629 199 0.037
regulation of cell development GO:0060284 263 0.037
response to nutrient GO:0007584 248 0.036
enzyme linked receptor protein signaling pathway GO:0007167 116 0.034
positive regulation of multicellular organismal process GO:0051240 387 0.034
single organism biosynthetic process GO:0044711 342 0.033
reproduction GO:0000003 245 0.033
response to corticosteroid GO:0031960 235 0.033
aging GO:0007568 241 0.033
nucleoside phosphate metabolic process GO:0006753 283 0.031
negative regulation of rna biosynthetic process GO:1902679 118 0.031
response to peptide hormone GO:0043434 278 0.031
cellular component assembly GO:0022607 360 0.031
cellular amino acid metabolic process GO:0006520 107 0.030
negative regulation of developmental process GO:0051093 125 0.030
response to monosaccharide GO:0034284 159 0.029
osteoblast differentiation GO:0001649 26 0.029
negative regulation of multicellular organismal process GO:0051241 203 0.029
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.029
positive regulation of signaling GO:0023056 270 0.028
oxidation reduction process GO:0055114 304 0.028
regulation of nervous system development GO:0051960 264 0.028
organonitrogen compound biosynthetic process GO:1901566 167 0.028
ion transmembrane transport GO:0034220 365 0.028
catabolic process GO:0009056 351 0.027
response to other organism GO:0051707 220 0.027
male sex differentiation GO:0046661 64 0.027
response to nutrient levels GO:0031667 370 0.026
transcription from rna polymerase ii promoter GO:0006366 252 0.026
organelle organization GO:0006996 266 0.026
response to oxygen levels GO:0070482 265 0.025
anatomical structure formation involved in morphogenesis GO:0048646 83 0.025
multicellular organism growth GO:0035264 1 0.025
negative regulation of cell differentiation GO:0045596 99 0.025
cell morphogenesis involved in differentiation GO:0000904 119 0.025
vasculature development GO:0001944 70 0.024
male gonad development GO:0008584 59 0.024
development of primary sexual characteristics GO:0045137 107 0.024
carbohydrate derivative metabolic process GO:1901135 346 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.024
cellular catabolic process GO:0044248 295 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.024
cellular component movement GO:0006928 248 0.023
positive regulation of bone mineralization GO:0030501 4 0.023
proteolysis GO:0006508 175 0.023
regulation of osteoblast differentiation GO:0045667 14 0.023
elastic fiber assembly GO:0048251 1 0.022
response to peptide GO:1901652 292 0.022
cell growth GO:0016049 104 0.022
central nervous system development GO:0007417 311 0.022
cellular amine metabolic process GO:0044106 38 0.022
response to glucocorticoid GO:0051384 223 0.021
negative regulation of biosynthetic process GO:0009890 168 0.021
cellular amino acid biosynthetic process GO:0008652 32 0.021
positive regulation of cell proliferation GO:0008284 249 0.020
regulation of response to stress GO:0080134 126 0.020
reproductive process GO:0022414 372 0.020
Rat
cellular component morphogenesis GO:0032989 155 0.020
regulation of cellular component organization GO:0051128 368 0.020
female pregnancy GO:0007565 122 0.020
Rat
ribose phosphate metabolic process GO:0019693 235 0.020
nucleotide metabolic process GO:0009117 279 0.020
regulation of molecular function GO:0065009 398 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.018
cellular response to nitrogen compound GO:1901699 210 0.018
negative regulation of cell communication GO:0010648 158 0.018
negative regulation of cellular component organization GO:0051129 83 0.018
regulation of cellular ketone metabolic process GO:0010565 27 0.018
negative regulation of rna metabolic process GO:0051253 123 0.018
negative regulation of nervous system development GO:0051961 79 0.018
response to estrogen GO:0043627 232 0.018
immune system process GO:0002376 204 0.018
response to extracellular stimulus GO:0009991 380 0.018
cellular response to stress GO:0033554 269 0.017
multicellular organism reproduction GO:0032504 233 0.017
gonad development GO:0008406 104 0.017
amine metabolic process GO:0009308 38 0.017
male gamete generation GO:0048232 99 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.017
single organism reproductive process GO:0044702 297 0.017
Rat
lipid metabolic process GO:0006629 283 0.017
negative regulation of response to stimulus GO:0048585 155 0.017
response to metal ion GO:0010038 253 0.017
response to ketone GO:1901654 182 0.017
negative regulation of transcription dna templated GO:0045892 116 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
aorta development GO:0035904 2 0.017
negative regulation of molecular function GO:0044092 133 0.017
secretion GO:0046903 307 0.016
response to glucose GO:0009749 136 0.016
positive regulation of biomineral tissue development GO:0070169 4 0.016
neuron projection development GO:0031175 273 0.016
cardiovascular system development GO:0072358 134 0.016
ras protein signal transduction GO:0007265 29 0.016
response to hexose GO:0009746 144 0.016
blood vessel development GO:0001568 69 0.016
multi organism reproductive process GO:0044703 262 0.016
Rat
nucleobase containing small molecule metabolic process GO:0055086 316 0.016
response to growth factor GO:0070848 189 0.016
sex differentiation GO:0007548 113 0.016
regulation of phosphorylation GO:0042325 248 0.016
rho protein signal transduction GO:0007266 11 0.016
organic acid biosynthetic process GO:0016053 83 0.015
single organism catabolic process GO:0044712 283 0.015
negative regulation of protein metabolic process GO:0051248 114 0.015
regulation of bmp signaling pathway GO:0030510 2 0.015
axonogenesis GO:0007409 71 0.015
cellular response to external stimulus GO:0071496 118 0.015
cell migration GO:0016477 197 0.015
transmembrane transport GO:0055085 412 0.015
positive regulation of transcription dna templated GO:0045893 197 0.015
regulation of anatomical structure morphogenesis GO:0022603 141 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
angiogenesis GO:0001525 53 0.014
epithelium development GO:0060429 96 0.014
positive regulation of molecular function GO:0044093 230 0.014
axon development GO:0061564 96 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
response to carbohydrate GO:0009743 183 0.014
regulation of apoptotic process GO:0042981 335 0.014
reproductive structure development GO:0048608 128 0.014
gastrulation GO:0007369 2 0.013
negative regulation of nucleic acid templated transcription GO:1903507 117 0.013
programmed cell death GO:0012501 392 0.013
neuron development GO:0048666 286 0.013
protein oligomerization GO:0051259 191 0.013
organophosphate metabolic process GO:0019637 370 0.013
positive regulation of cell communication GO:0010647 271 0.013
positive regulation of gene expression GO:0010628 244 0.013
developmental process involved in reproduction GO:0003006 159 0.013
secretion by cell GO:0032940 248 0.013
cellular response to peptide hormone stimulus GO:0071375 120 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
negative regulation of catalytic activity GO:0043086 103 0.013
cellular component biogenesis GO:0044085 368 0.013
response to oxidative stress GO:0006979 186 0.013
development of primary male sexual characteristics GO:0046546 59 0.013
response to inorganic substance GO:0010035 377 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
response to cytokine GO:0034097 215 0.012
cell projection organization GO:0030030 302 0.012
response to decreased oxygen levels GO:0036293 237 0.012
regulation of cell projection organization GO:0031344 175 0.012
positive regulation of nervous system development GO:0051962 178 0.012
response to wounding GO:0009611 254 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
lipid biosynthetic process GO:0008610 128 0.012
regulation of interferon gamma production GO:0032649 3 0.012
spermatogenesis GO:0007283 99 0.012
localization of cell GO:0051674 202 0.012
protein phosphorylation GO:0006468 345 0.012
protein complex subunit organization GO:0071822 302 0.012
cell morphogenesis GO:0000902 142 0.012
regulation of cellular localization GO:0060341 263 0.012
regulation of catalytic activity GO:0050790 304 0.012
homeostatic process GO:0042592 331 0.012
regulation of intracellular signal transduction GO:1902531 218 0.012
connective tissue development GO:0061448 33 0.012
macromolecule localization GO:0033036 252 0.012
regulation of neuron differentiation GO:0045664 208 0.012
negative regulation of signal transduction GO:0009968 83 0.012
neuronal action potential GO:0019228 35 0.011
tube development GO:0035295 89 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.011
intracellular transport GO:0046907 185 0.011
positive regulation of cell death GO:0010942 184 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.011
epithelial cell differentiation GO:0030855 71 0.011
bmp signaling pathway GO:0030509 4 0.011
membrane organization GO:0061024 94 0.011
collagen fibril organization GO:0030199 1 0.011
regulation of neuron projection development GO:0010975 161 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
locomotion GO:0040011 237 0.011
response to vitamin d GO:0033280 34 0.010
response to ionizing radiation GO:0010212 59 0.010
regulation of programmed cell death GO:0043067 341 0.010
positive regulation of cellular amine metabolic process GO:0033240 3 0.010
carbohydrate derivative catabolic process GO:1901136 147 0.010
cytokine biosynthetic process GO:0042089 3 0.010
artery development GO:0060840 3 0.010
regulation of ossification GO:0030278 32 0.010
cell motility GO:0048870 202 0.010
response to fluoride GO:1902617 3 0.010
single organism organelle organization GO:1902589 180 0.010
cell cycle GO:0007049 101 0.010

Efemp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.112
musculoskeletal system disease DOID:17 0 0.112
nervous system disease DOID:863 0 0.041
connective tissue disease DOID:65 0 0.029
muscular disease DOID:0080000 0 0.021
bone development disease DOID:0080006 0 0.020
bone disease DOID:0080001 0 0.020
osteochondrodysplasia DOID:2256 0 0.017
central nervous system disease DOID:331 0 0.012