Rattus norvegicus

299 known processes

Egfr

epidermal growth factor receptor

(Aliases: ErbB-1,ERBB1,Errp)

Egfr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to peptide hormone stimulus GO:0071375 120 0.944
Rat
response to insulin GO:0032868 133 0.787
Rat
response to glucocorticoid GO:0051384 223 0.643
enzyme linked receptor protein signaling pathway GO:0007167 116 0.591
cellular response to peptide GO:1901653 133 0.578
Rat
cellular response to endogenous stimulus GO:0071495 377 0.569
cellular response to hormone stimulus GO:0032870 247 0.565
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.539
oxoacid metabolic process GO:0043436 290 0.528
cellular response to insulin stimulus GO:0032869 81 0.526
Rat
organic acid metabolic process GO:0006082 292 0.523
cellular response to nitrogen compound GO:1901699 210 0.459
Mouse Rat
cellular response to organonitrogen compound GO:0071417 197 0.445
Mouse Rat
positive regulation of response to stimulus GO:0048584 285 0.435
response to peptide GO:1901652 292 0.414
Rat
carboxylic acid metabolic process GO:0019752 289 0.412
immune system process GO:0002376 204 0.405
Fly
positive regulation of cell communication GO:0010647 271 0.401
response to peptide hormone GO:0043434 278 0.400
Rat
regulation of cell proliferation GO:0042127 359 0.378
olfactory learning GO:0008355 1 0.371
Fly
cellular lipid metabolic process GO:0044255 208 0.312
positive regulation of multicellular organismal process GO:0051240 387 0.308
signal transduction by phosphorylation GO:0023014 144 0.308
regulation of intracellular signal transduction GO:1902531 218 0.266
intracellular signal transduction GO:0035556 314 0.265
positive regulation of signaling GO:0023056 270 0.264
positive regulation of intracellular signal transduction GO:1902533 138 0.257
cellular amino acid metabolic process GO:0006520 107 0.257
regulation of cellular protein metabolic process GO:0032268 267 0.254
regulation of mapk cascade GO:0043408 116 0.252
monocarboxylic acid metabolic process GO:0032787 152 0.230
insulin receptor signaling pathway GO:0008286 24 0.220
wound healing GO:0042060 122 0.213
Fly
regulation of molecular function GO:0065009 398 0.213
regulation of phosphorylation GO:0042325 248 0.202
apoptotic process GO:0006915 381 0.202
response to oxidative stress GO:0006979 186 0.198
regulation of protein kinase activity GO:0045859 105 0.197
cellular response to oxygen containing compound GO:1901701 386 0.193
regulation of protein phosphorylation GO:0001932 183 0.186
aging GO:0007568 241 0.184
regulation of phosphate metabolic process GO:0019220 349 0.177
positive regulation of signal transduction GO:0009967 175 0.175
programmed cell death GO:0012501 392 0.171
cellular component morphogenesis GO:0032989 155 0.164
reproductive system development GO:0061458 128 0.163
Mouse Fly
positive regulation of apoptotic process GO:0043065 154 0.161
mapk cascade GO:0000165 140 0.156
cellular amine metabolic process GO:0044106 38 0.156
gland development GO:0048732 155 0.154
lipid metabolic process GO:0006629 283 0.154
cellular response to stress GO:0033554 269 0.153
single organism biosynthetic process GO:0044711 342 0.151
regulation of protein modification process GO:0031399 194 0.146
positive regulation of protein metabolic process GO:0051247 178 0.145
oxidation reduction process GO:0055114 304 0.144
positive regulation of cell proliferation GO:0008284 249 0.144
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.143
cellular ketone metabolic process GO:0042180 51 0.142
protein phosphorylation GO:0006468 345 0.141
regulation of programmed cell death GO:0043067 341 0.137
protein complex assembly GO:0006461 263 0.135
regulation of multicellular organismal development GO:2000026 376 0.135
Fly
positive regulation of protein phosphorylation GO:0001934 135 0.133
response to molecule of bacterial origin GO:0002237 194 0.132
regeneration GO:0031099 163 0.127
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.125
erbb signaling pathway GO:0038127 23 0.125
positive regulation of mapk cascade GO:0043410 92 0.123
regulation of rna biosynthetic process GO:2001141 381 0.121
positive regulation of phosphate metabolic process GO:0045937 262 0.120
positive regulation of cellular protein metabolic process GO:0032270 167 0.120
response to nutrient GO:0007584 248 0.119
negative regulation of metabolic process GO:0009892 331 0.119
rhythmic process GO:0048511 156 0.118
regulation of signal transduction GO:0009966 318 0.118
positive regulation of cellular biosynthetic process GO:0031328 295 0.116
cellular component assembly GO:0022607 360 0.114
Fly
rna metabolic process GO:0016070 406 0.114
response to toxic substance GO:0009636 133 0.113
response to estrogen GO:0043627 232 0.113
response to decreased oxygen levels GO:0036293 237 0.112
positive regulation of cell death GO:0010942 184 0.112
positive regulation of phosphorus metabolic process GO:0010562 262 0.111
inflammatory response GO:0006954 150 0.110
anatomical structure morphogenesis GO:0009653 298 0.110
response to corticosteroid GO:0031960 235 0.110
response to wounding GO:0009611 254 0.107
regulation of protein metabolic process GO:0051246 289 0.105
organ regeneration GO:0031100 101 0.104
developmental process involved in reproduction GO:0003006 159 0.103
Mouse Fly
negative regulation of programmed cell death GO:0043069 183 0.102
response to nutrient levels GO:0031667 370 0.100
response to extracellular stimulus GO:0009991 380 0.100
defense response GO:0006952 194 0.100
positive regulation of biosynthetic process GO:0009891 319 0.099
rna biosynthetic process GO:0032774 380 0.098
central nervous system development GO:0007417 311 0.098
response to reactive oxygen species GO:0000302 120 0.097
small molecule biosynthetic process GO:0044283 124 0.096
response to radiation GO:0009314 137 0.096
response to oxygen levels GO:0070482 265 0.095
protein complex biogenesis GO:0070271 263 0.094
activation of protein kinase activity GO:0032147 47 0.094
amine metabolic process GO:0009308 38 0.093
response to cytokine GO:0034097 215 0.093
muscle cell proliferation GO:0033002 84 0.093
positive regulation of developmental process GO:0051094 283 0.092
positive regulation of cell differentiation GO:0045597 217 0.091
cytoskeleton organization GO:0007010 111 0.091
tissue development GO:0009888 252 0.090
Mouse Rat Fly
neurological system process GO:0050877 219 0.090
homeostatic process GO:0042592 331 0.090
macromolecular complex subunit organization GO:0043933 339 0.089
response to ethanol GO:0045471 162 0.089
Fly
cognition GO:0050890 92 0.088
reproductive process GO:0022414 372 0.088
regulation of cellular amine metabolic process GO:0033238 8 0.088
positive regulation of protein transport GO:0051222 41 0.087
response to lipopolysaccharide GO:0032496 191 0.087
negative regulation of signal transduction GO:0009968 83 0.086
Fly
negative regulation of cell communication GO:0010648 158 0.084
Fly
regulation of secretion GO:0051046 224 0.084
regulation of cellular component organization GO:0051128 368 0.083
organic hydroxy compound metabolic process GO:1901615 115 0.083
protein complex subunit organization GO:0071822 302 0.082
regulation of cellular ketone metabolic process GO:0010565 27 0.079
response to amino acid GO:0043200 75 0.078
Mouse
nitrogen compound transport GO:0071705 229 0.078
catabolic process GO:0009056 351 0.078
regulation of kinase activity GO:0043549 117 0.077
negative regulation of response to stimulus GO:0048585 155 0.077
Fly
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.077
behavior GO:0007610 205 0.075
fatty acid metabolic process GO:0006631 99 0.075
lipid localization GO:0010876 62 0.075
positive regulation of transport GO:0051050 245 0.075
Rat
vesicle mediated transport GO:0016192 181 0.074
anatomical structure formation involved in morphogenesis GO:0048646 83 0.074
Fly
carboxylic acid biosynthetic process GO:0046394 83 0.073
macromolecule localization GO:0033036 252 0.073
cellular catabolic process GO:0044248 295 0.073
regulation of rna metabolic process GO:0051252 391 0.073
response to hypoxia GO:0001666 231 0.072
regulation of nucleic acid templated transcription GO:1903506 380 0.071
peptidyl amino acid modification GO:0018193 126 0.071
response to growth factor GO:0070848 189 0.070
regulation of hormone levels GO:0010817 187 0.070
negative regulation of cellular metabolic process GO:0031324 281 0.070
positive regulation of transferase activity GO:0051347 81 0.070
negative regulation of macromolecule metabolic process GO:0010605 260 0.069
neuron projection development GO:0031175 273 0.069
cellular response to organic cyclic compound GO:0071407 202 0.068
protein localization GO:0008104 191 0.067
steroid metabolic process GO:0008202 73 0.067
negative regulation of signaling GO:0023057 157 0.067
Fly
response to estradiol GO:0032355 164 0.067
protein heterooligomerization GO:0051291 89 0.067
neuron apoptotic process GO:0051402 88 0.066
response to hydrogen peroxide GO:0042542 89 0.066
positive regulation of transcription dna templated GO:0045893 197 0.066
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.066
cellular response to lipid GO:0071396 201 0.065
response to vitamin GO:0033273 131 0.064
positive regulation of protein kinase activity GO:0045860 73 0.064
response to other organism GO:0051707 220 0.064
positive regulation of rna biosynthetic process GO:1902680 197 0.063
macromolecular complex assembly GO:0065003 273 0.063
transcription dna templated GO:0006351 377 0.062
regulation of cell differentiation GO:0045595 320 0.062
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.061
positive regulation of catalytic activity GO:0043085 184 0.061
cell morphogenesis GO:0000902 142 0.061
regulation of anatomical structure morphogenesis GO:0022603 141 0.060
Fly
positive regulation of phosphorylation GO:0042327 177 0.060
response to ketone GO:1901654 182 0.059
negative regulation of apoptotic process GO:0043066 181 0.059
organic acid biosynthetic process GO:0016053 83 0.059
secretion by cell GO:0032940 248 0.059
liver development GO:0001889 90 0.058
regulation of cellular amino acid metabolic process GO:0006521 2 0.058
regulation of protein secretion GO:0050708 28 0.058
learning or memory GO:0007611 90 0.057
positive regulation of programmed cell death GO:0043068 157 0.057
regulation of response to stress GO:0080134 126 0.057
carbohydrate derivative metabolic process GO:1901135 346 0.056
negative regulation of phosphate metabolic process GO:0045936 80 0.056
regulation of nervous system development GO:0051960 264 0.056
organonitrogen compound biosynthetic process GO:1901566 167 0.055
cellular component biogenesis GO:0044085 368 0.055
Fly
regulation of phosphorus metabolic process GO:0051174 349 0.055
positive regulation of nucleic acid templated transcription GO:1903508 197 0.055
response to organophosphorus GO:0046683 102 0.055
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.055
memory GO:0007613 54 0.055
single organism catabolic process GO:0044712 283 0.054
single organism reproductive process GO:0044702 297 0.054
hepaticobiliary system development GO:0061008 90 0.054
circulatory system development GO:0072359 134 0.054
neuron development GO:0048666 286 0.054
response to ionizing radiation GO:0010212 59 0.054
lipid biosynthetic process GO:0008610 128 0.053
cellular response to steroid hormone stimulus GO:0071383 93 0.053
biphenyl catabolic process GO:0070980 2 0.052
regulation of cellular localization GO:0060341 263 0.052
negative regulation of phosphorus metabolic process GO:0010563 80 0.051
regulation of system process GO:0044057 208 0.051
regulation of apoptotic process GO:0042981 335 0.051
response to transition metal nanoparticle GO:1990267 122 0.051
organic substance catabolic process GO:1901575 316 0.051
urogenital system development GO:0001655 78 0.051
Fly
immune response GO:0006955 104 0.051
ion transmembrane transport GO:0034220 365 0.050
regulation of cell development GO:0060284 263 0.050
Fly
cellular component movement GO:0006928 248 0.050
Mouse Fly
hormone metabolic process GO:0042445 69 0.050
positive regulation of cellular component organization GO:0051130 200 0.049
single organism organelle organization GO:1902589 180 0.049
positive regulation of rna metabolic process GO:0051254 203 0.049
olfactory behavior GO:0042048 2 0.048
Fly
positive regulation of secretion by cell GO:1903532 128 0.048
cell cycle GO:0007049 101 0.048
cellular response to abiotic stimulus GO:0071214 85 0.048
single organism carbohydrate metabolic process GO:0044723 118 0.048
cytokine production GO:0001816 61 0.047
multicellular organism reproduction GO:0032504 233 0.047
small gtpase mediated signal transduction GO:0007264 36 0.047
multicellular organismal reproductive process GO:0048609 233 0.047
cell projection organization GO:0030030 302 0.047
negative regulation of cell death GO:0060548 229 0.047
response to biotic stimulus GO:0009607 226 0.047
epidermal growth factor receptor signaling pathway GO:0007173 23 0.047
cardiovascular system development GO:0072358 134 0.046
response to bacterium GO:0009617 200 0.046
regulation of neuron death GO:1901214 115 0.046
nucleic acid templated transcription GO:0097659 379 0.046
regulation of cell motility GO:2000145 131 0.046
regulation of protein transport GO:0051223 68 0.046
organic anion transport GO:0015711 132 0.045
regulation of smooth muscle cell proliferation GO:0048660 75 0.045
regulation of secretion by cell GO:1903530 208 0.045
secretion GO:0046903 307 0.045
positive regulation of cellular amine metabolic process GO:0033240 3 0.045
nucleoside phosphate metabolic process GO:0006753 283 0.044
negative regulation of gene expression GO:0010629 199 0.044
neuron differentiation GO:0030182 368 0.044
regulation of anatomical structure size GO:0090066 135 0.044
cell type specific apoptotic process GO:0097285 134 0.043
nucleobase containing small molecule metabolic process GO:0055086 316 0.043
proteolysis GO:0006508 175 0.043
growth GO:0040007 165 0.043
negative regulation of biosynthetic process GO:0009890 168 0.043
cellular hormone metabolic process GO:0034754 49 0.043
axonogenesis GO:0007409 71 0.043
Rat
heart morphogenesis GO:0003007 3 0.042
transcription from rna polymerase ii promoter GO:0006366 252 0.042
protein autophosphorylation GO:0046777 66 0.042
cell migration GO:0016477 197 0.041
Mouse Fly
regulation of map kinase activity GO:0043405 53 0.041
organophosphate metabolic process GO:0019637 370 0.041
single organism behavior GO:0044708 130 0.040
nucleotide metabolic process GO:0009117 279 0.040
response to external biotic stimulus GO:0043207 221 0.040
cell projection morphogenesis GO:0048858 123 0.040
negative regulation of molecular function GO:0044092 133 0.040
chemosensory behavior GO:0007635 2 0.040
Fly
regulation of neurogenesis GO:0050767 247 0.040
response to monosaccharide GO:0034284 159 0.039
cell adhesion GO:0007155 110 0.039
Fly
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.039
positive regulation of protein modification process GO:0031401 142 0.038
vasculature development GO:0001944 70 0.038
ras protein signal transduction GO:0007265 29 0.038
response to starvation GO:0042594 59 0.038
regulation of neuron apoptotic process GO:0043523 83 0.038
response to purine containing compound GO:0014074 126 0.038
acute inflammatory response GO:0002526 58 0.037
aromatic compound catabolic process GO:0019439 168 0.037
response to alkaloid GO:0043279 132 0.037
regulation of transcription dna templated GO:0006355 374 0.037
actin cytoskeleton organization GO:0030036 73 0.036
cellular response to corticosteroid stimulus GO:0071384 69 0.036
regulation of transferase activity GO:0051338 123 0.036
metal ion transport GO:0030001 289 0.036
response to mechanical stimulus GO:0009612 134 0.036
cellular response to growth factor stimulus GO:0071363 162 0.035
positive regulation of cell motility GO:2000147 97 0.035
response to carbohydrate GO:0009743 183 0.034
receptor mediated endocytosis GO:0006898 42 0.034
response to metal ion GO:0010038 253 0.034
ovulation cycle GO:0042698 67 0.034
localization of cell GO:0051674 202 0.034
Mouse Fly
regulation of hydrolase activity GO:0051336 143 0.034
amide transport GO:0042886 105 0.034
placenta development GO:0001890 22 0.034
Mouse
ribose phosphate metabolic process GO:0019693 235 0.033
phenylpropanoid catabolic process GO:0046271 3 0.033
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.033
dna metabolic process GO:0006259 96 0.033
blood circulation GO:0008015 183 0.033
cellular response to cytokine stimulus GO:0071345 127 0.033
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.033
Rat
regulation of cell migration GO:0030334 128 0.033
glycosyl compound metabolic process GO:1901657 182 0.033
cation transport GO:0006812 382 0.033
establishment of protein localization GO:0045184 141 0.032
hormone secretion GO:0046879 115 0.032
neuron death GO:0070997 127 0.032
negative regulation of transcription dna templated GO:0045892 116 0.032
glycerolipid metabolic process GO:0046486 67 0.032
gonad development GO:0008406 104 0.032
Fly
generation of precursor metabolites and energy GO:0006091 62 0.032
chemotaxis GO:0006935 66 0.032
hemopoiesis GO:0030097 34 0.032
transmembrane transport GO:0055085 412 0.032
cell motility GO:0048870 202 0.032
Mouse Fly
unsaturated fatty acid metabolic process GO:0033559 39 0.032
learning GO:0007612 33 0.031
Fly
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.031
female pregnancy GO:0007565 122 0.031
regulation of catalytic activity GO:0050790 304 0.031
response to inorganic substance GO:0010035 377 0.030
protein transport GO:0015031 132 0.030
reproduction GO:0000003 245 0.030
organic acid transport GO:0015849 116 0.030
innate immune response GO:0045087 35 0.030
regulation of membrane potential GO:0042391 110 0.030
regulation of growth GO:0040008 105 0.030
protein secretion GO:0009306 34 0.030
negative regulation of cell proliferation GO:0008285 119 0.030
development of primary sexual characteristics GO:0045137 107 0.030
Fly
response to heat GO:0009408 60 0.029
actin filament based process GO:0030029 86 0.029
regulation of protein localization GO:0032880 81 0.029
response to hexose GO:0009746 144 0.029
muscle system process GO:0003012 115 0.029
positive regulation of immune system process GO:0002684 90 0.029
organ morphogenesis GO:0009887 75 0.029
Mouse Rat Fly
regulation of cell morphogenesis GO:0022604 77 0.029
regulation of response to external stimulus GO:0032101 106 0.029
positive regulation of nervous system development GO:0051962 178 0.029
regulation of cellular response to stress GO:0080135 49 0.029
sex differentiation GO:0007548 113 0.028
Fly
negative regulation of cellular biosynthetic process GO:0031327 161 0.028
regulation of metal ion transport GO:0010959 118 0.028
ribonucleoside metabolic process GO:0009119 174 0.028
neuron projection morphogenesis GO:0048812 122 0.028
protein oligomerization GO:0051259 191 0.028
sensory perception GO:0007600 101 0.028
axon development GO:0061564 96 0.028
Rat
cellular response to external stimulus GO:0071496 118 0.028
negative regulation of cellular protein metabolic process GO:0032269 106 0.028
female gonad development GO:0008585 53 0.028
icosanoid metabolic process GO:0006690 38 0.028
multi organism reproductive process GO:0044703 262 0.027
Fly
renal system development GO:0072001 67 0.027
Fly
cell cell signaling GO:0007267 335 0.027
monosaccharide metabolic process GO:0005996 61 0.027
female sex differentiation GO:0046660 59 0.027
digestive system development GO:0055123 41 0.027
Mouse Fly
chemical homeostasis GO:0048878 292 0.027
blood vessel morphogenesis GO:0048514 58 0.026
nucleoside metabolic process GO:0009116 179 0.026
organic cyclic compound catabolic process GO:1901361 175 0.026
positive regulation of kinase activity GO:0033674 77 0.026
response to temperature stimulus GO:0009266 94 0.026
negative regulation of rna biosynthetic process GO:1902679 118 0.026
negative regulation of protein metabolic process GO:0051248 114 0.026
regulation of peptide transport GO:0090087 87 0.026
smooth muscle cell proliferation GO:0048659 77 0.026
regulation of cellular catabolic process GO:0031329 101 0.026
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.026
metal ion homeostasis GO:0055065 186 0.025
response to glucose GO:0009749 136 0.025
lipid transport GO:0006869 61 0.025
estrogen catabolic process GO:0006711 1 0.025
positive regulation of map kinase activity GO:0043406 46 0.025
carboxylic acid transport GO:0046942 115 0.025
development of primary female sexual characteristics GO:0046545 56 0.025
positive regulation of secretion GO:0051047 140 0.025
single organism cell adhesion GO:0098602 46 0.025
Fly
heart development GO:0007507 72 0.025
regulation of homeostatic process GO:0032844 101 0.025
circadian rhythm GO:0007623 88 0.025
peptide transport GO:0015833 97 0.025
chordate embryonic development GO:0043009 18 0.024
Mouse
alcohol metabolic process GO:0006066 77 0.024
regulation of immune system process GO:0002682 123 0.024
Fly
biological adhesion GO:0022610 110 0.024
Fly
regulation of protein serine threonine kinase activity GO:0071900 64 0.024
regulation of cellular component movement GO:0051270 150 0.024
negative regulation of nucleic acid templated transcription GO:1903507 117 0.024
fatty acid derivative metabolic process GO:1901568 38 0.024
regulation of cell cycle GO:0051726 73 0.024
ion homeostasis GO:0050801 212 0.024
nucleoside triphosphate metabolic process GO:0009141 144 0.024
positive regulation of response to external stimulus GO:0032103 51 0.024
peptidyl tyrosine modification GO:0018212 72 0.024
gamete generation GO:0007276 124 0.024
Fly
purine containing compound metabolic process GO:0072521 253 0.024
response to acid chemical GO:0001101 222 0.023
Mouse
regulation of reactive oxygen species metabolic process GO:2000377 26 0.023
heterocycle catabolic process GO:0046700 167 0.023
locomotion GO:0040011 237 0.023
Mouse Fly
cardiac chamber development GO:0003205 1 0.023
cellular response to ketone GO:1901655 51 0.023
phospholipid metabolic process GO:0006644 61 0.022
positive regulation of protein secretion GO:0050714 19 0.022
receptor metabolic process GO:0043112 18 0.022
positive regulation of gene expression GO:0010628 244 0.022
ovulation cycle process GO:0022602 50 0.022
b cell differentiation GO:0030183 2 0.022
purine nucleoside metabolic process GO:0042278 169 0.022
synaptic transmission GO:0007268 235 0.022
positive regulation of cell migration GO:0030335 96 0.022
cation homeostasis GO:0055080 195 0.022
digestive tract development GO:0048565 39 0.021
Mouse Fly
intracellular transport GO:0046907 185 0.021
positive regulation of locomotion GO:0040017 102 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.021
g protein coupled receptor signaling pathway GO:0007186 242 0.021
positive regulation of leukocyte differentiation GO:1902107 13 0.021
organophosphate biosynthetic process GO:0090407 143 0.021
multicellular organism growth GO:0035264 1 0.021
regulation of erk1 and erk2 cascade GO:0070372 41 0.021
organelle organization GO:0006996 266 0.021
regulation of organelle organization GO:0033043 80 0.021
regulation of receptor activity GO:0010469 29 0.021
cell morphogenesis involved in differentiation GO:0000904 119 0.021
Rat
eye morphogenesis GO:0048592 4 0.021
Fly
cell activation GO:0001775 97 0.021
glial cell differentiation GO:0010001 65 0.021
purine nucleoside triphosphate metabolic process GO:0009144 141 0.021
response to zinc ion GO:0010043 39 0.021
regulation of hormone secretion GO:0046883 106 0.021
dna replication GO:0006260 37 0.021
apoptotic signaling pathway GO:0097190 27 0.021
Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.020
negative regulation of cell differentiation GO:0045596 99 0.020
Fly
cellular ion homeostasis GO:0006873 184 0.020
response to vitamin d GO:0033280 34 0.020
cellular response to lipopolysaccharide GO:0071222 55 0.020
nucleoside phosphate catabolic process GO:1901292 140 0.020
muscle structure development GO:0061061 87 0.020
Rat
carbohydrate metabolic process GO:0005975 130 0.020
monovalent inorganic cation transport GO:0015672 172 0.020
positive regulation of organelle organization GO:0010638 48 0.020
terpenoid metabolic process GO:0006721 37 0.020
regulation of cell projection organization GO:0031344 175 0.020
muscle contraction GO:0006936 88 0.020
multicellular organismal homeostasis GO:0048871 49 0.020
Fly
organonitrogen compound catabolic process GO:1901565 179 0.019
anion transport GO:0006820 178 0.019
circulatory system process GO:0003013 183 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.019
negative regulation of transport GO:0051051 136 0.019
blood vessel development GO:0001568 69 0.019
immune system development GO:0002520 41 0.019
cellular response to acid chemical GO:0071229 75 0.019
Mouse
purine ribonucleotide metabolic process GO:0009150 227 0.019
cellular response to glucocorticoid stimulus GO:0071385 68 0.019
reactive oxygen species metabolic process GO:0072593 37 0.019
organic hydroxy compound biosynthetic process GO:1901617 51 0.019
halogenated hydrocarbon metabolic process GO:0042197 4 0.019
regulation of peptide secretion GO:0002791 82 0.019
positive regulation of cytokine production GO:0001819 42 0.019
inorganic ion transmembrane transport GO:0098660 229 0.019
regulation of ion transport GO:0043269 245 0.019
salivary gland development GO:0007431 3 0.019
Mouse Fly
negative regulation of neuron apoptotic process GO:0043524 45 0.019
axis specification GO:0009798 4 0.019
Fly
regulation of neuron differentiation GO:0045664 208 0.018
regulation of inflammatory response GO:0050727 48 0.018
single organism intracellular transport GO:1902582 166 0.018
cellular metal ion homeostasis GO:0006875 172 0.018
alpha amino acid metabolic process GO:1901605 71 0.018
protein maturation GO:0051604 68 0.018
small molecule catabolic process GO:0044282 59 0.018
tube development GO:0035295 89 0.018
purine nucleotide metabolic process GO:0006163 229 0.018
epithelial cell differentiation GO:0030855 71 0.018
Fly
regulation of neuron projection development GO:0010975 161 0.018
glucan metabolic process GO:0044042 23 0.018
negative regulation of multicellular organismal process GO:0051241 203 0.018
Fly
regulation of blood vessel size GO:0050880 89 0.018
signal release GO:0023061 145 0.018
cellular response to mechanical stimulus GO:0071260 48 0.018
cellular response to alcohol GO:0097306 87 0.018
positive regulation of molecular function GO:0044093 230 0.017
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.017
regulation of transporter activity GO:0032409 50 0.017
regulation of immunoglobulin production GO:0002637 4 0.017
carbohydrate derivative biosynthetic process GO:1901137 124 0.017
negative regulation of neuron death GO:1901215 69 0.017

Egfr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.037
disease of anatomical entity DOID:7 0 0.032
nervous system disease DOID:863 0 0.032