Rattus norvegicus

109 known processes

Eif2b1

eukaryotic translation initiation factor 2B, subunit 1 alpha

(Aliases: eIF-2a)

Eif2b1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of translational initiation GO:0045947 5 0.266
translation GO:0006412 35 0.253
ribonucleoside metabolic process GO:0009119 174 0.117
response to peptide GO:1901652 292 0.086
negative regulation of metabolic process GO:0009892 331 0.076
ribonucleotide catabolic process GO:0009261 136 0.070
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.068
ensheathment of neurons GO:0007272 40 0.068
ribonucleoside triphosphate catabolic process GO:0009203 122 0.067
purine nucleotide metabolic process GO:0006163 229 0.064
carbohydrate derivative metabolic process GO:1901135 346 0.063
purine nucleoside triphosphate catabolic process GO:0009146 122 0.061
female sex differentiation GO:0046660 59 0.059
nucleotide metabolic process GO:0009117 279 0.059
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.059
reproductive process GO:0022414 372 0.058
nucleobase containing small molecule metabolic process GO:0055086 316 0.057
organophosphate metabolic process GO:0019637 370 0.057
aging GO:0007568 241 0.054
carbohydrate derivative catabolic process GO:1901136 147 0.053
purine containing compound metabolic process GO:0072521 253 0.053
purine ribonucleoside catabolic process GO:0046130 124 0.052
response to glucose GO:0009749 136 0.051
nucleoside phosphate metabolic process GO:0006753 283 0.049
response to carbohydrate GO:0009743 183 0.049
purine nucleoside catabolic process GO:0006152 124 0.049
ribonucleotide metabolic process GO:0009259 231 0.048
ribose phosphate metabolic process GO:0019693 235 0.048
nucleoside catabolic process GO:0009164 126 0.045
organonitrogen compound catabolic process GO:1901565 179 0.044
ribonucleoside triphosphate metabolic process GO:0009199 141 0.044
rna biosynthetic process GO:0032774 380 0.044
purine containing compound catabolic process GO:0072523 138 0.044
regulation of cellular protein metabolic process GO:0032268 267 0.043
neuronal action potential GO:0019228 35 0.043
axon ensheathment GO:0008366 40 0.040
regulation of translation GO:0006417 27 0.040
development of primary sexual characteristics GO:0045137 107 0.039
purine nucleotide catabolic process GO:0006195 136 0.039
nucleoside triphosphate metabolic process GO:0009141 144 0.038
positive regulation of phosphate metabolic process GO:0045937 262 0.037
response to monosaccharide GO:0034284 159 0.037
regulation of translation in response to stress GO:0043555 5 0.036
organophosphate catabolic process GO:0046434 148 0.036
aromatic compound catabolic process GO:0019439 168 0.035
response to peptide hormone GO:0043434 278 0.034
gonad development GO:0008406 104 0.033
transmission of nerve impulse GO:0019226 42 0.033
multicellular organism reproduction GO:0032504 233 0.033
nucleobase containing compound catabolic process GO:0034655 152 0.032
response to hexose GO:0009746 144 0.032
sex differentiation GO:0007548 113 0.031
regulation of nucleotide metabolic process GO:0006140 117 0.031
regulation of phosphorus metabolic process GO:0051174 349 0.031
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.031
development of primary female sexual characteristics GO:0046545 56 0.031
rhythmic process GO:0048511 156 0.030
vesicle mediated transport GO:0016192 181 0.029
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.029
reproduction GO:0000003 245 0.028
nucleotide catabolic process GO:0009166 139 0.028
regulation of rna biosynthetic process GO:2001141 381 0.028
nucleoside triphosphate catabolic process GO:0009143 123 0.028
regulation of phosphate metabolic process GO:0019220 349 0.027
regulation of protein metabolic process GO:0051246 289 0.026
regulation of cell cycle GO:0051726 73 0.026
gtp metabolic process GO:0046039 72 0.026
cellular amine metabolic process GO:0044106 38 0.026
multicellular organismal reproductive process GO:0048609 233 0.025
developmental process involved in reproduction GO:0003006 159 0.025
negative regulation of protein metabolic process GO:0051248 114 0.025
positive regulation of phosphorus metabolic process GO:0010562 262 0.025
female gonad development GO:0008585 53 0.025
regulation of catalytic activity GO:0050790 304 0.024
positive regulation of nucleotide metabolic process GO:0045981 91 0.024
positive regulation of hydrolase activity GO:0051345 86 0.024
regulation of purine nucleotide metabolic process GO:1900542 115 0.023
purine ribonucleotide metabolic process GO:0009150 227 0.023
heterocycle catabolic process GO:0046700 167 0.023
glycosyl compound metabolic process GO:1901657 182 0.023
apoptotic process GO:0006915 381 0.023
purine ribonucleoside metabolic process GO:0046128 168 0.023
nucleoside metabolic process GO:0009116 179 0.022
organic cyclic compound catabolic process GO:1901361 175 0.022
transcription dna templated GO:0006351 377 0.022
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.022
purine nucleoside triphosphate metabolic process GO:0009144 141 0.022
ribonucleoside catabolic process GO:0042454 126 0.022
reproductive structure development GO:0048608 128 0.021
guanosine containing compound catabolic process GO:1901069 71 0.021
eye morphogenesis GO:0048592 4 0.020
negative regulation of gene expression GO:0010629 199 0.020
positive regulation of gene expression GO:0010628 244 0.020
translational initiation GO:0006413 8 0.020
negative regulation of cellular metabolic process GO:0031324 281 0.020
single organism catabolic process GO:0044712 283 0.020
multicellular organismal signaling GO:0035637 44 0.020
negative regulation of biosynthetic process GO:0009890 168 0.019
regulation of nucleotide catabolic process GO:0030811 65 0.019
ovulation cycle process GO:0022602 50 0.019
regulation of membrane potential GO:0042391 110 0.019
amine metabolic process GO:0009308 38 0.019
rna metabolic process GO:0016070 406 0.019
positive regulation of cellular catabolic process GO:0031331 71 0.019
reproductive system development GO:0061458 128 0.019
cellular response to stress GO:0033554 269 0.019
action potential GO:0001508 54 0.018
nucleic acid templated transcription GO:0097659 379 0.018
cellular catabolic process GO:0044248 295 0.018
organelle organization GO:0006996 266 0.018
negative regulation of macromolecule metabolic process GO:0010605 260 0.018
gtp catabolic process GO:0006184 71 0.018
regulation of cell proliferation GO:0042127 359 0.018
positive regulation of gtp catabolic process GO:0033126 48 0.017
cellular nitrogen compound catabolic process GO:0044270 163 0.017
cellular component assembly GO:0022607 360 0.017
maintenance of location GO:0051235 17 0.017
positive regulation of catalytic activity GO:0043085 184 0.017
negative regulation of cellular protein metabolic process GO:0032269 106 0.017
purine nucleoside monophosphate metabolic process GO:0009126 84 0.016
regulation of rna metabolic process GO:0051252 391 0.016
oligodendrocyte differentiation GO:0048709 32 0.016
positive regulation of nucleotide catabolic process GO:0030813 53 0.016
regulation of catabolic process GO:0009894 113 0.016
regulation of gtpase activity GO:0043087 57 0.016
nucleoside phosphate catabolic process GO:1901292 140 0.016
positive regulation of molecular function GO:0044093 230 0.016
astrocyte development GO:0014002 4 0.015
cation transport GO:0006812 382 0.015
central nervous system development GO:0007417 311 0.015
nitrogen compound transport GO:0071705 229 0.015
regulation of molecular function GO:0065009 398 0.015
organonitrogen compound biosynthetic process GO:1901566 167 0.015
purine nucleoside metabolic process GO:0042278 169 0.015
macromolecular complex subunit organization GO:0043933 339 0.015
response to heat GO:0009408 60 0.014
catabolic process GO:0009056 351 0.014
intracellular transport GO:0046907 185 0.014
ovulation cycle GO:0042698 67 0.014
positive regulation of biosynthetic process GO:0009891 319 0.014
positive regulation of gtpase activity GO:0043547 47 0.014
oxoacid metabolic process GO:0043436 290 0.014
histone methylation GO:0016571 3 0.014
regulation of purine nucleotide catabolic process GO:0033121 65 0.013
negative regulation of cell death GO:0060548 229 0.013
glial cell differentiation GO:0010001 65 0.013
single organism intracellular transport GO:1902582 166 0.013
transcription from rna polymerase ii promoter GO:0006366 252 0.012
embryo development GO:0009790 49 0.012
regulation of nucleic acid templated transcription GO:1903506 380 0.012
myelination GO:0042552 39 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
single organism reproductive process GO:0044702 297 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
regulation of gtp catabolic process GO:0033124 58 0.012
response to acid chemical GO:0001101 222 0.012
nucleoside monophosphate metabolic process GO:0009123 93 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
secretion GO:0046903 307 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
synaptic vesicle endocytosis GO:0048488 4 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
regulation of synaptic vesicle endocytosis GO:1900242 1 0.011
positive regulation of rna biosynthetic process GO:1902680 197 0.011
glial cell development GO:0021782 19 0.011
response to temperature stimulus GO:0009266 94 0.010
head development GO:0060322 247 0.010
macromolecular complex assembly GO:0065003 273 0.010
organic substance catabolic process GO:1901575 316 0.010
single organism cellular localization GO:1902580 102 0.010
regulation of cellular component organization GO:0051128 368 0.010
positive regulation of nucleoside metabolic process GO:0045979 55 0.010
regulation of nucleoside metabolic process GO:0009118 66 0.010

Eif2b1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
nervous system disease DOID:863 0 0.031
central nervous system disease DOID:331 0 0.018
brain disease DOID:936 0 0.012