Rattus norvegicus

12 known processes

Eif4a1

eukaryotic translation initiation factor 4A, isoform 1

Eif4a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein complex biogenesis GO:0070271 263 0.208
nucleoside phosphate metabolic process GO:0006753 283 0.137
Yeast
reproductive process GO:0022414 372 0.134
nucleic acid templated transcription GO:0097659 379 0.133
rna biosynthetic process GO:0032774 380 0.131
anatomical structure morphogenesis GO:0009653 298 0.115
regulation of rna metabolic process GO:0051252 391 0.096
regulation of molecular function GO:0065009 398 0.086
rna metabolic process GO:0016070 406 0.084
regulation of nucleic acid templated transcription GO:1903506 380 0.080
multi organism reproductive process GO:0044703 262 0.080
macromolecular complex subunit organization GO:0043933 339 0.072
organelle organization GO:0006996 266 0.070
positive regulation of nucleic acid templated transcription GO:1903508 197 0.069
nucleotide metabolic process GO:0009117 279 0.068
Yeast
reproduction GO:0000003 245 0.065
transcription from rna polymerase ii promoter GO:0006366 252 0.064
multicellular organismal reproductive process GO:0048609 233 0.064
macromolecular complex assembly GO:0065003 273 0.064
carbohydrate derivative metabolic process GO:1901135 346 0.064
Yeast
transcription dna templated GO:0006351 377 0.064
cell cycle GO:0007049 101 0.061
protein complex assembly GO:0006461 263 0.058
cellular component biogenesis GO:0044085 368 0.055
cellular amino acid metabolic process GO:0006520 107 0.054
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.051
multicellular organism reproduction GO:0032504 233 0.050
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.050
regulation of rna biosynthetic process GO:2001141 381 0.049
positive regulation of gene expression GO:0010628 244 0.049
chromosome organization GO:0051276 36 0.048
purine containing compound metabolic process GO:0072521 253 0.048
Yeast
meiotic cell cycle process GO:1903046 3 0.047
regulation of organelle organization GO:0033043 80 0.047
regulation of transcription dna templated GO:0006355 374 0.046
response to purine containing compound GO:0014074 126 0.046
positive regulation of biosynthetic process GO:0009891 319 0.046
cellular homeostasis GO:0019725 252 0.045
protein complex subunit organization GO:0071822 302 0.045
cellular component assembly GO:0022607 360 0.044
cellular catabolic process GO:0044248 295 0.044
Yeast
tissue development GO:0009888 252 0.042
head development GO:0060322 247 0.042
regulation of cellular component organization GO:0051128 368 0.040
single organism reproductive process GO:0044702 297 0.039
negative regulation of cell death GO:0060548 229 0.039
positive regulation of cellular component organization GO:0051130 200 0.038
negative regulation of cellular metabolic process GO:0031324 281 0.038
anterior posterior pattern specification GO:0009952 1 0.037
single organism biosynthetic process GO:0044711 342 0.036
response to peptide hormone GO:0043434 278 0.035
organophosphate metabolic process GO:0019637 370 0.034
Yeast
axis specification GO:0009798 4 0.034
oxoacid metabolic process GO:0043436 290 0.034
liver development GO:0001889 90 0.034
chemical homeostasis GO:0048878 292 0.034
sexual reproduction GO:0019953 148 0.033
organic substance catabolic process GO:1901575 316 0.033
Yeast
negative regulation of apoptotic process GO:0043066 181 0.033
nucleobase containing small molecule metabolic process GO:0055086 316 0.032
Yeast
positive regulation of cellular biosynthetic process GO:0031328 295 0.031
positive regulation of rna metabolic process GO:0051254 203 0.031
gland development GO:0048732 155 0.031
negative regulation of gene expression GO:0010629 199 0.031
organ regeneration GO:0031100 101 0.031
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.030
regulation of cellular protein metabolic process GO:0032268 267 0.030
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.030
organic acid metabolic process GO:0006082 292 0.029
carboxylic acid metabolic process GO:0019752 289 0.029
response to nutrient levels GO:0031667 370 0.029
positive regulation of rna biosynthetic process GO:1902680 197 0.029
locomotion GO:0040011 237 0.029
neuron projection development GO:0031175 273 0.029
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.029
programmed cell death GO:0012501 392 0.029
cellular amine metabolic process GO:0044106 38 0.029
cellular response to oxidative stress GO:0034599 76 0.028
response to organophosphorus GO:0046683 102 0.028
nucleoside metabolic process GO:0009116 179 0.028
Yeast
homeostatic process GO:0042592 331 0.028
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.028
response to extracellular stimulus GO:0009991 380 0.028
negative regulation of metabolic process GO:0009892 331 0.027
protein localization GO:0008104 191 0.027
cellular response to oxygen containing compound GO:1901701 386 0.027
gamete generation GO:0007276 124 0.027
cellular response to stress GO:0033554 269 0.027
single organism organelle organization GO:1902589 180 0.026
aromatic compound catabolic process GO:0019439 168 0.026
Yeast
response to oxidative stress GO:0006979 186 0.026
regulation of phosphate metabolic process GO:0019220 349 0.026
oxidation reduction process GO:0055114 304 0.025
protein transport GO:0015031 132 0.025
response to cytokine GO:0034097 215 0.025
purine nucleotide metabolic process GO:0006163 229 0.025
Yeast
ribose phosphate metabolic process GO:0019693 235 0.025
Yeast
positive regulation of cellular protein metabolic process GO:0032270 167 0.025
regulation of catalytic activity GO:0050790 304 0.024
hepaticobiliary system development GO:0061008 90 0.024
negative regulation of macromolecule metabolic process GO:0010605 260 0.024
intracellular transport GO:0046907 185 0.024
brain development GO:0007420 247 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.024
negative regulation of cell communication GO:0010648 158 0.023
cellular response to endogenous stimulus GO:0071495 377 0.023
regulation of meiotic cell cycle GO:0051445 3 0.023
regulation of secretion GO:0051046 224 0.023
positive regulation of protein metabolic process GO:0051247 178 0.022
catabolic process GO:0009056 351 0.022
Yeast
negative regulation of cellular biosynthetic process GO:0031327 161 0.022
cell projection organization GO:0030030 302 0.022
carbohydrate derivative biosynthetic process GO:1901137 124 0.022
positive regulation of phosphate metabolic process GO:0045937 262 0.022
dna metabolic process GO:0006259 96 0.022
regulation of neuron differentiation GO:0045664 208 0.021
neuron differentiation GO:0030182 368 0.021
regulation of cellular catabolic process GO:0031329 101 0.021
central nervous system development GO:0007417 311 0.021
cellular response to peptide hormone stimulus GO:0071375 120 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.021
growth GO:0040007 165 0.021
secretion by cell GO:0032940 248 0.021
regulation of multicellular organismal development GO:2000026 376 0.021
response to peptide GO:1901652 292 0.021
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.021
negative regulation of rna metabolic process GO:0051253 123 0.021
cellular response to nitrogen compound GO:1901699 210 0.021
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
glycosyl compound metabolic process GO:1901657 182 0.020
Yeast
single organism catabolic process GO:0044712 283 0.020
Yeast
cell cell signaling GO:0007267 335 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.020
positive regulation of molecular function GO:0044093 230 0.020
embryonic pattern specification GO:0009880 1 0.020
translation GO:0006412 35 0.020
Yeast
nucleocytoplasmic transport GO:0006913 48 0.019
spermatogenesis GO:0007283 99 0.019
apoptotic process GO:0006915 381 0.019
purine ribonucleoside metabolic process GO:0046128 168 0.019
Yeast
regulation of cell development GO:0060284 263 0.019
response to inorganic substance GO:0010035 377 0.019
cellular macromolecule localization GO:0070727 122 0.019
nucleoside phosphate catabolic process GO:1901292 140 0.019
Yeast
positive regulation of transport GO:0051050 245 0.019
positive regulation of response to stimulus GO:0048584 285 0.019
metal ion homeostasis GO:0055065 186 0.019
embryonic axis specification GO:0000578 1 0.019
ribonucleotide metabolic process GO:0009259 231 0.019
Yeast
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
defense response GO:0006952 194 0.018
organonitrogen compound biosynthetic process GO:1901566 167 0.018
response to nutrient GO:0007584 248 0.018
protein phosphorylation GO:0006468 345 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
negative regulation of biosynthetic process GO:0009890 168 0.018
chromosome segregation GO:0007059 2 0.018
negative regulation of rna biosynthetic process GO:1902679 118 0.018
regulation of immune system process GO:0002682 123 0.018
response to glucocorticoid GO:0051384 223 0.018
regulation of anatomical structure size GO:0090066 135 0.018
regulation of cellular localization GO:0060341 263 0.018
cellular macromolecular complex assembly GO:0034622 58 0.018
cellular response to insulin stimulus GO:0032869 81 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.018
Yeast
forebrain development GO:0030900 98 0.017
cellular response to cytokine stimulus GO:0071345 127 0.017
negative regulation of nucleic acid templated transcription GO:1903507 117 0.017
purine containing compound biosynthetic process GO:0072522 85 0.017
cellular component movement GO:0006928 248 0.017
regulation of cell differentiation GO:0045595 320 0.017
nucleoside monophosphate metabolic process GO:0009123 93 0.017
Yeast
nucleotide catabolic process GO:0009166 139 0.017
Yeast
ncrna processing GO:0034470 3 0.017
negative regulation of innate immune response GO:0045824 4 0.017
cellular response to external stimulus GO:0071496 118 0.017
response to growth factor GO:0070848 189 0.016
male gamete generation GO:0048232 99 0.016
cellular nitrogen compound catabolic process GO:0044270 163 0.016
Yeast
response to estrogen GO:0043627 232 0.016
regulation of programmed cell death GO:0043067 341 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.016
regulation of dna metabolic process GO:0051052 60 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
sensory organ development GO:0007423 74 0.016
cytoplasmic transport GO:0016482 115 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
purine nucleoside metabolic process GO:0042278 169 0.016
Yeast
ras protein signal transduction GO:0007265 29 0.016
gastrulation GO:0007369 2 0.016
regulation of cell motility GO:2000145 131 0.016
nucleobase containing compound catabolic process GO:0034655 152 0.016
Yeast
response to corticosteroid GO:0031960 235 0.016
heterocycle catabolic process GO:0046700 167 0.016
Yeast
circulatory system development GO:0072359 134 0.016
positive regulation of transcription dna templated GO:0045893 197 0.015
regulation of protein metabolic process GO:0051246 289 0.015
cellular response to hormone stimulus GO:0032870 247 0.015
purine nucleotide catabolic process GO:0006195 136 0.015
Yeast
cellular ketone metabolic process GO:0042180 51 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
proteolysis GO:0006508 175 0.015
regulation of cell proliferation GO:0042127 359 0.015
response to temperature stimulus GO:0009266 94 0.015
multi multicellular organism process GO:0044706 138 0.015
regeneration GO:0031099 163 0.015
neuron development GO:0048666 286 0.015
negative regulation of signaling GO:0023057 157 0.015
cellular protein complex assembly GO:0043623 44 0.015
ribonucleoside metabolic process GO:0009119 174 0.014
Yeast
aging GO:0007568 241 0.014
single organism carbohydrate metabolic process GO:0044723 118 0.014
positive regulation of nucleotide catabolic process GO:0030813 53 0.014
carbohydrate metabolic process GO:0005975 130 0.014
positive regulation of nucleoside metabolic process GO:0045979 55 0.014
ribonucleoside triphosphate metabolic process GO:0009199 141 0.014
Yeast
regulation of nucleotide metabolic process GO:0006140 117 0.014
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
cardiovascular system development GO:0072358 134 0.014
regulation of catabolic process GO:0009894 113 0.014
response to metal ion GO:0010038 253 0.014
tolerance induction dependent upon immune response GO:0002461 2 0.014
positive regulation of nervous system development GO:0051962 178 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
Yeast
response to radiation GO:0009314 137 0.014
multicellular organism growth GO:0035264 1 0.013
cellular chemical homeostasis GO:0055082 247 0.013
enzyme linked receptor protein signaling pathway GO:0007167 116 0.013
muscle organ morphogenesis GO:0048644 1 0.013
intracellular signal transduction GO:0035556 314 0.013
hematopoietic progenitor cell differentiation GO:0002244 2 0.013
regulation of secretion by cell GO:1903530 208 0.013
behavior GO:0007610 205 0.013
cytoskeleton dependent cytokinesis GO:0061640 2 0.013
positive regulation of protein modification process GO:0031401 142 0.013
positive regulation of nucleotide metabolic process GO:0045981 91 0.013
positive regulation of developmental process GO:0051094 283 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
positive regulation of catabolic process GO:0009896 78 0.013
positive regulation of transferase activity GO:0051347 81 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.013
cellular response to nutrient levels GO:0031669 60 0.013
response to estradiol GO:0032355 164 0.013
ncrna metabolic process GO:0034660 8 0.013
secretion GO:0046903 307 0.013
tongue morphogenesis GO:0043587 3 0.013
regulation of purine nucleotide metabolic process GO:1900542 115 0.013
mitotic spindle organization GO:0007052 2 0.013
response to hexose GO:0009746 144 0.012
positive regulation of growth GO:0045927 55 0.012
cellular response to extracellular stimulus GO:0031668 73 0.012
cation transport GO:0006812 382 0.012
cellular response to peptide GO:1901653 133 0.012
regulation of neurogenesis GO:0050767 247 0.012
positive regulation of multicellular organismal process GO:0051240 387 0.012
synaptic transmission GO:0007268 235 0.012
amine metabolic process GO:0009308 38 0.012
eye morphogenesis GO:0048592 4 0.012
protein oligomerization GO:0051259 191 0.012
regulation of hydrolase activity GO:0051336 143 0.012
regulation of response to stress GO:0080134 126 0.012
alpha amino acid metabolic process GO:1901605 71 0.012
dephosphorylation GO:0016311 98 0.012
lipid storage GO:0019915 1 0.012
macromolecule localization GO:0033036 252 0.012
regulation of apoptotic process GO:0042981 335 0.012
positive regulation of organelle organization GO:0010638 48 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
developmental process involved in reproduction GO:0003006 159 0.011
cell motility GO:0048870 202 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
regulation of transferase activity GO:0051338 123 0.011
cell cycle process GO:0022402 57 0.011
ion homeostasis GO:0050801 212 0.011
fertilization GO:0009566 3 0.011
response to wounding GO:0009611 254 0.011
cell morphogenesis GO:0000902 142 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
actin nucleation GO:0045010 2 0.011
positive regulation of dna metabolic process GO:0051054 39 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
Yeast
cell part morphogenesis GO:0032990 123 0.011
sulfur compound metabolic process GO:0006790 70 0.011
regulation of protein modification process GO:0031399 194 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
mesenchymal cell proliferation GO:0010463 4 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
Yeast
regulation of protein complex assembly GO:0043254 33 0.011
response to glucose GO:0009749 136 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.011
biological adhesion GO:0022610 110 0.011
protein polymerization GO:0051258 22 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
Yeast
mitotic cell cycle GO:0000278 49 0.011
neuron death GO:0070997 127 0.011
immune system process GO:0002376 204 0.011
circadian rhythm GO:0007623 88 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
circulatory system process GO:0003013 183 0.011
posttranscriptional regulation of gene expression GO:0010608 37 0.011
ribonucleoside monophosphate metabolic process GO:0009161 88 0.010
Yeast
cellular protein localization GO:0034613 122 0.010
regulation of nucleotide catabolic process GO:0030811 65 0.010
carbohydrate derivative catabolic process GO:1901136 147 0.010
Yeast
heart morphogenesis GO:0003007 3 0.010
regulation of signal transduction GO:0009966 318 0.010
cellular modified amino acid metabolic process GO:0006575 61 0.010
response to interleukin 1 GO:0070555 55 0.010
positive regulation of cellular catabolic process GO:0031331 71 0.010
localization of cell GO:0051674 202 0.010
negative regulation of transcription dna templated GO:0045892 116 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
regulation of cellular component biogenesis GO:0044087 86 0.010
regulation of cell projection organization GO:0031344 175 0.010
lipid metabolic process GO:0006629 283 0.010

Eif4a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.011
cancer DOID:162 0 0.011
nervous system disease DOID:863 0 0.011
disease of anatomical entity DOID:7 0 0.011
organ system cancer DOID:0050686 0 0.010