Rattus norvegicus

0 known processes

Eif4b

eukaryotic translation initiation factor 4B

(Aliases: MGC94923)

Eif4b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.203
positive regulation of biosynthetic process GO:0009891 319 0.198
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.182
positive regulation of cellular biosynthetic process GO:0031328 295 0.173
cell type specific apoptotic process GO:0097285 134 0.143
regulation of signal transduction GO:0009966 318 0.140
Fly
regulation of apoptotic process GO:0042981 335 0.136
intracellular signal transduction GO:0035556 314 0.132
Fly
regulation of rna biosynthetic process GO:2001141 381 0.123
protein complex subunit organization GO:0071822 302 0.114
protein complex assembly GO:0006461 263 0.109
regulation of protein metabolic process GO:0051246 289 0.104
nucleic acid templated transcription GO:0097659 379 0.100
regulation of cellular protein metabolic process GO:0032268 267 0.097
positive regulation of gene expression GO:0010628 244 0.095
positive regulation of transcription dna templated GO:0045893 197 0.088
cellular response to oxygen containing compound GO:1901701 386 0.084
neuron apoptotic process GO:0051402 88 0.083
negative regulation of metabolic process GO:0009892 331 0.080
apoptotic process GO:0006915 381 0.079
positive regulation of nucleic acid templated transcription GO:1903508 197 0.078
rna metabolic process GO:0016070 406 0.077
positive regulation of rna biosynthetic process GO:1902680 197 0.076
positive regulation of rna metabolic process GO:0051254 203 0.076
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.076
regulation of programmed cell death GO:0043067 341 0.076
regulation of rna metabolic process GO:0051252 391 0.075
negative regulation of macromolecule metabolic process GO:0010605 260 0.075
negative regulation of cellular metabolic process GO:0031324 281 0.075
macromolecular complex assembly GO:0065003 273 0.073
programmed cell death GO:0012501 392 0.073
response to extracellular stimulus GO:0009991 380 0.070
regulation of nucleic acid templated transcription GO:1903506 380 0.070
transcription dna templated GO:0006351 377 0.069
macromolecular complex subunit organization GO:0043933 339 0.069
protein complex biogenesis GO:0070271 263 0.067
protein oligomerization GO:0051259 191 0.067
single organism reproductive process GO:0044702 297 0.066
cellular protein localization GO:0034613 122 0.065
cellular component movement GO:0006928 248 0.065
regulation of phosphate metabolic process GO:0019220 349 0.064
regulation of transcription dna templated GO:0006355 374 0.063
negative regulation of apoptotic process GO:0043066 181 0.062
cellular component biogenesis GO:0044085 368 0.062
reproductive process GO:0022414 372 0.062
negative regulation of cell death GO:0060548 229 0.059
regulation of cell proliferation GO:0042127 359 0.059
nucleotide metabolic process GO:0009117 279 0.058
neuron death GO:0070997 127 0.056
response to cytokine GO:0034097 215 0.054
multi organism reproductive process GO:0044703 262 0.051
rna biosynthetic process GO:0032774 380 0.051
negative regulation of neuron death GO:1901215 69 0.050
regulation of cellular localization GO:0060341 263 0.050
negative regulation of signaling GO:0023057 157 0.049
response to nutrient levels GO:0031667 370 0.049
cellular response to peptide GO:1901653 133 0.049
multicellular organism reproduction GO:0032504 233 0.049
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.049
regulation of molecular function GO:0065009 398 0.048
cellular response to hormone stimulus GO:0032870 247 0.048
regulation of neuron death GO:1901214 115 0.048
nucleobase containing small molecule metabolic process GO:0055086 316 0.048
protein localization GO:0008104 191 0.048
positive regulation of signal transduction GO:0009967 175 0.048
Fly
protein localization to organelle GO:0033365 57 0.047
regulation of protein modification process GO:0031399 194 0.047
response to peptide hormone GO:0043434 278 0.047
cellular response to endogenous stimulus GO:0071495 377 0.047
regulation of establishment of protein localization GO:0070201 69 0.046
regulation of phosphorus metabolic process GO:0051174 349 0.046
positive regulation of cell proliferation GO:0008284 249 0.046
organophosphate metabolic process GO:0019637 370 0.046
response to peptide GO:1901652 292 0.045
negative regulation of programmed cell death GO:0043069 183 0.044
cellular macromolecule localization GO:0070727 122 0.042
carboxylic acid metabolic process GO:0019752 289 0.042
regulation of cellular component organization GO:0051128 368 0.041
regulation of phosphorylation GO:0042325 248 0.041
proteolysis GO:0006508 175 0.040
regulation of response to stress GO:0080134 126 0.039
negative regulation of response to stimulus GO:0048585 155 0.039
protein phosphorylation GO:0006468 345 0.039
positive regulation of programmed cell death GO:0043068 157 0.039
cellular response to cytokine stimulus GO:0071345 127 0.039
positive regulation of phosphate metabolic process GO:0045937 262 0.038
establishment of protein localization GO:0045184 141 0.038
cellular response to nitrogen compound GO:1901699 210 0.038
cellular component assembly GO:0022607 360 0.038
single organism biosynthetic process GO:0044711 342 0.038
organonitrogen compound catabolic process GO:1901565 179 0.038
positive regulation of protein metabolic process GO:0051247 178 0.037
positive regulation of response to stimulus GO:0048584 285 0.037
Fly
positive regulation of apoptotic process GO:0043065 154 0.036
negative regulation of signal transduction GO:0009968 83 0.036
regulation of catabolic process GO:0009894 113 0.036
macromolecule localization GO:0033036 252 0.035
negative regulation of cellular biosynthetic process GO:0031327 161 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.035
regulation of neuron apoptotic process GO:0043523 83 0.035
reproductive system development GO:0061458 128 0.034
positive regulation of intracellular signal transduction GO:1902533 138 0.034
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.033
ribonucleotide metabolic process GO:0009259 231 0.033
regulation of locomotion GO:0040012 148 0.032
positive regulation of cell death GO:0010942 184 0.032
multi multicellular organism process GO:0044706 138 0.032
cellular response to stress GO:0033554 269 0.032
tissue development GO:0009888 252 0.031
purine nucleotide metabolic process GO:0006163 229 0.031
regulation of intracellular signal transduction GO:1902531 218 0.031
Fly
purine containing compound metabolic process GO:0072521 253 0.031
purine ribonucleotide metabolic process GO:0009150 227 0.031
negative regulation of multicellular organismal process GO:0051241 203 0.031
nucleoside phosphate metabolic process GO:0006753 283 0.031
cellular ketone metabolic process GO:0042180 51 0.031
negative regulation of gene expression GO:0010629 199 0.030
positive regulation of signaling GO:0023056 270 0.030
Fly
neuron differentiation GO:0030182 368 0.030
regulation of cell motility GO:2000145 131 0.030
catabolic process GO:0009056 351 0.030
multicellular organismal reproductive process GO:0048609 233 0.030
homeostatic process GO:0042592 331 0.029
rhythmic process GO:0048511 156 0.029
negative regulation of protein metabolic process GO:0051248 114 0.029
negative regulation of cellular protein metabolic process GO:0032269 106 0.029
negative regulation of neuron apoptotic process GO:0043524 45 0.029
cell projection organization GO:0030030 302 0.029
response to inorganic substance GO:0010035 377 0.029
cation transport GO:0006812 382 0.028
cellular amine metabolic process GO:0044106 38 0.028
enzyme linked receptor protein signaling pathway GO:0007167 116 0.028
positive regulation of cell development GO:0010720 176 0.027
response to decreased oxygen levels GO:0036293 237 0.027
regulation of catalytic activity GO:0050790 304 0.027
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.027
ribose phosphate metabolic process GO:0019693 235 0.026
positive regulation of cellular component organization GO:0051130 200 0.026
cellular response to organonitrogen compound GO:0071417 197 0.026
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.026
organelle organization GO:0006996 266 0.026
regulation of cell differentiation GO:0045595 320 0.026
regulation of cellular amine metabolic process GO:0033238 8 0.026
response to biotic stimulus GO:0009607 226 0.026
negative regulation of molecular function GO:0044092 133 0.026
regulation of protein transport GO:0051223 68 0.025
positive regulation of locomotion GO:0040017 102 0.025
regulation of cellular ketone metabolic process GO:0010565 27 0.025
translation GO:0006412 35 0.025
Fly
carbohydrate derivative metabolic process GO:1901135 346 0.025
positive regulation of molecular function GO:0044093 230 0.025
neurological system process GO:0050877 219 0.025
positive regulation of transport GO:0051050 245 0.025
gamete generation GO:0007276 124 0.025
positive regulation of phosphorus metabolic process GO:0010562 262 0.024
positive regulation of cellular protein metabolic process GO:0032270 167 0.024
immune system process GO:0002376 204 0.024
protein transport GO:0015031 132 0.024
central nervous system development GO:0007417 311 0.024
purine ribonucleoside metabolic process GO:0046128 168 0.024
organophosphate biosynthetic process GO:0090407 143 0.023
circulatory system development GO:0072359 134 0.023
regulation of membrane potential GO:0042391 110 0.023
cell morphogenesis involved in differentiation GO:0000904 119 0.023
cellular response to oxidative stress GO:0034599 76 0.022
head development GO:0060322 247 0.022
positive regulation of phosphorylation GO:0042327 177 0.022
growth GO:0040007 165 0.022
regulation of protein targeting GO:1903533 28 0.022
regulation of homeostatic process GO:0032844 101 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.022
amine metabolic process GO:0009308 38 0.022
apoptotic signaling pathway GO:0097190 27 0.022
positive regulation of cell differentiation GO:0045597 217 0.021
regulation of peptide transport GO:0090087 87 0.021
negative regulation of biosynthetic process GO:0009890 168 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
negative regulation of cell communication GO:0010648 158 0.021
negative regulation of nucleic acid templated transcription GO:1903507 117 0.021
response to molecule of bacterial origin GO:0002237 194 0.021
positive regulation of cell migration GO:0030335 96 0.021
neuron projection development GO:0031175 273 0.021
female pregnancy GO:0007565 122 0.021
cellular component morphogenesis GO:0032989 155 0.020
nucleotide biosynthetic process GO:0009165 98 0.020
positive regulation of multicellular organismal process GO:0051240 387 0.020
cell growth GO:0016049 104 0.020
peptidyl amino acid modification GO:0018193 126 0.020
transcription from rna polymerase ii promoter GO:0006366 252 0.020
regulation of cellular response to stress GO:0080135 49 0.020
cellular response to growth factor stimulus GO:0071363 162 0.020
regulation of cell migration GO:0030334 128 0.020
nucleoside phosphate biosynthetic process GO:1901293 102 0.020
response to oxidative stress GO:0006979 186 0.020
sexual reproduction GO:0019953 148 0.020
protein maturation GO:0051604 68 0.019
protein homooligomerization GO:0051260 91 0.019
gland development GO:0048732 155 0.019
regulation of kinase activity GO:0043549 117 0.019
response to nutrient GO:0007584 248 0.019
regulation of nucleocytoplasmic transport GO:0046822 28 0.019
regulation of cell development GO:0060284 263 0.019
negative regulation of cellular component organization GO:0051129 83 0.019
vesicle mediated transport GO:0016192 181 0.019
positive regulation of cell projection organization GO:0031346 111 0.019
cellular response to organic cyclic compound GO:0071407 202 0.019
regulation of nucleotide metabolic process GO:0006140 117 0.019
positive regulation of developmental process GO:0051094 283 0.019
regulation of neurogenesis GO:0050767 247 0.018
mapk cascade GO:0000165 140 0.018
regulation of ion transport GO:0043269 245 0.018
reproductive structure development GO:0048608 128 0.018
carbohydrate metabolic process GO:0005975 130 0.018
cellular response to lipid GO:0071396 201 0.018
locomotion GO:0040011 237 0.018
axon development GO:0061564 96 0.018
cellular chemical homeostasis GO:0055082 247 0.018
axonogenesis GO:0007409 71 0.018
cell morphogenesis GO:0000902 142 0.018
dna metabolic process GO:0006259 96 0.018
purine containing compound biosynthetic process GO:0072522 85 0.018
regulation of hydrolase activity GO:0051336 143 0.018
response to growth factor GO:0070848 189 0.017
cellular homeostasis GO:0019725 252 0.017
signal transduction by phosphorylation GO:0023014 144 0.017
macroautophagy GO:0016236 4 0.017
regulation of immune system process GO:0002682 123 0.017
anatomical structure morphogenesis GO:0009653 298 0.017
single organism catabolic process GO:0044712 283 0.017
cellular response to external stimulus GO:0071496 118 0.017
regulation of metal ion transport GO:0010959 118 0.017
localization of cell GO:0051674 202 0.017
regulation of hormone levels GO:0010817 187 0.017
gonad development GO:0008406 104 0.017
negative regulation of developmental process GO:0051093 125 0.017
cellular catabolic process GO:0044248 295 0.017
ribonucleoside metabolic process GO:0009119 174 0.017
cell cycle GO:0007049 101 0.017
positive regulation of cell communication GO:0010647 271 0.017
Fly
organic substance catabolic process GO:1901575 316 0.017
negative regulation of rna metabolic process GO:0051253 123 0.017
cell migration GO:0016477 197 0.017
positive regulation of cellular component movement GO:0051272 102 0.016
cellular lipid metabolic process GO:0044255 208 0.016
cellular carbohydrate metabolic process GO:0044262 72 0.016
response to carbohydrate GO:0009743 183 0.016
regulation of protein localization GO:0032880 81 0.016
single organism organelle organization GO:1902589 180 0.016
wnt signaling pathway GO:0016055 17 0.016
negative regulation of transcription dna templated GO:0045892 116 0.016
response to hypoxia GO:0001666 231 0.016
response to reactive oxygen species GO:0000302 120 0.016
developmental process involved in reproduction GO:0003006 159 0.016
cellular response to biotic stimulus GO:0071216 59 0.016
regulation of cellular catabolic process GO:0031329 101 0.016
regulation of system process GO:0044057 208 0.016
positive regulation of cytoplasmic transport GO:1903651 32 0.015
response to temperature stimulus GO:0009266 94 0.015
inflammatory response GO:0006954 150 0.015
muscle cell apoptotic process GO:0010657 30 0.015
response to bacterium GO:0009617 200 0.015
purine nucleoside metabolic process GO:0042278 169 0.015
response to ketone GO:1901654 182 0.015
guanosine containing compound metabolic process GO:1901068 74 0.015
organic acid metabolic process GO:0006082 292 0.015
positive regulation of response to external stimulus GO:0032103 51 0.015
regulation of mapk cascade GO:0043408 116 0.015
purine nucleotide biosynthetic process GO:0006164 83 0.015
neuron projection morphogenesis GO:0048812 122 0.015
negative regulation of phosphorus metabolic process GO:0010563 80 0.015
negative regulation of transport GO:0051051 136 0.015
response to radiation GO:0009314 137 0.015
single organism cellular localization GO:1902580 102 0.015
regulation of neuron differentiation GO:0045664 208 0.015
guanosine containing compound catabolic process GO:1901069 71 0.015
cellular amino acid metabolic process GO:0006520 107 0.015
lipid metabolic process GO:0006629 283 0.015
response to other organism GO:0051707 220 0.015
cytoplasmic transport GO:0016482 115 0.014
intracellular protein transport GO:0006886 79 0.014
nucleoside triphosphate metabolic process GO:0009141 144 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
cellular response to extracellular stimulus GO:0031668 73 0.014
muscle system process GO:0003012 115 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
regeneration GO:0031099 163 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
reproduction GO:0000003 245 0.014
calcium ion homeostasis GO:0055074 162 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
regulation of translation GO:0006417 27 0.014
regulation of multicellular organismal development GO:2000026 376 0.014
purine nucleoside triphosphate metabolic process GO:0009144 141 0.014
regulation of nervous system development GO:0051960 264 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.014
negative regulation of cell cycle phase transition GO:1901988 4 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
protein processing GO:0016485 68 0.014
single organism carbohydrate metabolic process GO:0044723 118 0.014
gastrulation GO:0007369 2 0.014
regulation of protein kinase activity GO:0045859 105 0.014
development of primary sexual characteristics GO:0045137 107 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
regulation of transferase activity GO:0051338 123 0.013
regulation of dna metabolic process GO:0051052 60 0.013
behavior GO:0007610 205 0.013
response to wounding GO:0009611 254 0.013
defense response GO:0006952 194 0.013
dephosphorylation GO:0016311 98 0.013
regulation of protein processing GO:0070613 50 0.013
cellular response to reactive oxygen species GO:0034614 55 0.013
positive regulation of neuron projection development GO:0010976 99 0.013
response to estrogen GO:0043627 232 0.013
organ regeneration GO:0031100 101 0.013
cellular response to peptide hormone stimulus GO:0071375 120 0.013
regulation of cell projection organization GO:0031344 175 0.013
regulation of intracellular transport GO:0032386 65 0.013
learning or memory GO:0007611 90 0.013
calcium ion transport GO:0006816 131 0.013
cell activation GO:0001775 97 0.013
spindle organization GO:0007051 2 0.013
nucleocytoplasmic transport GO:0006913 48 0.013
positive regulation of cell motility GO:2000147 97 0.013
regulation of cellular component movement GO:0051270 150 0.013
glycosyl compound catabolic process GO:1901658 126 0.013
immune response GO:0006955 104 0.013
regulation of cellular component biogenesis GO:0044087 86 0.013
aromatic compound catabolic process GO:0019439 168 0.013
positive regulation of immune system process GO:0002684 90 0.013
positive regulation of intracellular transport GO:0032388 39 0.013
purine ribonucleoside catabolic process GO:0046130 124 0.013
response to external biotic stimulus GO:0043207 221 0.013
ribonucleoside catabolic process GO:0042454 126 0.013
cellular response to nutrient levels GO:0031669 60 0.013
motor neuron axon guidance GO:0008045 1 0.013
positive regulation of protein phosphorylation GO:0001934 135 0.012
brain development GO:0007420 247 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.012
negative regulation of intracellular signal transduction GO:1902532 38 0.012
organonitrogen compound biosynthetic process GO:1901566 167 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
osteoblast differentiation GO:0001649 26 0.012
amide transport GO:0042886 105 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.012
single organism intracellular transport GO:1902582 166 0.012
regulation of neuron projection development GO:0010975 161 0.012
single organism behavior GO:0044708 130 0.012
glycogen metabolic process GO:0005977 23 0.012
positive regulation of dna metabolic process GO:0051054 39 0.012
ion transmembrane transport GO:0034220 365 0.012
neuronal action potential GO:0019228 35 0.012
protein targeting GO:0006605 61 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
cellular response to starvation GO:0009267 27 0.012
positive regulation of nervous system development GO:0051962 178 0.012
chemotaxis GO:0006935 66 0.012
multicellular organismal signaling GO:0035637 44 0.012
embryonic pattern specification GO:0009880 1 0.012
cell motility GO:0048870 202 0.012
posttranscriptional regulation of gene expression GO:0010608 37 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
regulation of proteolysis GO:0030162 66 0.011
negative regulation of innate immune response GO:0045824 4 0.011
cell projection morphogenesis GO:0048858 123 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
regulation of cell activation GO:0050865 50 0.011
regulation of proteasomal protein catabolic process GO:0061136 4 0.011
sex differentiation GO:0007548 113 0.011
negative regulation of nf kappab transcription factor activity GO:0032088 4 0.011
cellular response to alcohol GO:0097306 87 0.011
nucleotide catabolic process GO:0009166 139 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
regulation of response to external stimulus GO:0032101 106 0.011
response to glucocorticoid GO:0051384 223 0.011
peptide transport GO:0015833 97 0.011
renal system development GO:0072001 67 0.011
response to hexose GO:0009746 144 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
negative regulation of phosphate metabolic process GO:0045936 80 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
purine containing compound catabolic process GO:0072523 138 0.011
neuron development GO:0048666 286 0.011
ossification GO:0001503 70 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
action potential GO:0001508 54 0.011
multicellular organism growth GO:0035264 1 0.011
male gamete generation GO:0048232 99 0.011
organophosphate catabolic process GO:0046434 148 0.011
chemical homeostasis GO:0048878 292 0.011
epithelium development GO:0060429 96 0.011
cardiovascular system development GO:0072358 134 0.011
mitotic cell cycle GO:0000278 49 0.011
non canonical wnt signaling pathway GO:0035567 3 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
positive regulation of protein modification process GO:0031401 142 0.011
positive regulation of intracellular protein transport GO:0090316 20 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
nuclear transport GO:0051169 49 0.011
positive regulation of hydrolase activity GO:0051345 86 0.011
intracellular transport GO:0046907 185 0.011
cellular response to molecule of bacterial origin GO:0071219 56 0.011
necroptotic process GO:0070266 2 0.010
response to corticosteroid GO:0031960 235 0.010
response to estradiol GO:0032355 164 0.010
positive regulation of ion transport GO:0043270 94 0.010
leukocyte activation GO:0045321 76 0.010
lipid storage GO:0019915 1 0.010
epithelial cell differentiation GO:0030855 71 0.010
negative regulation of cytokine production GO:0001818 16 0.010
positive regulation of nucleotide metabolic process GO:0045981 91 0.010
blood circulation GO:0008015 183 0.010
nucleosome organization GO:0034728 1 0.010
response to ethanol GO:0045471 162 0.010
oxoacid metabolic process GO:0043436 290 0.010

Eif4b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.013