Rattus norvegicus

0 known processes

Eif4b

eukaryotic translation initiation factor 4B

(Aliases: MGC94923)

Eif4b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.203
positive regulation of biosynthetic process GO:0009891 319 0.198
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.182
positive regulation of cellular biosynthetic process GO:0031328 295 0.173
cell type specific apoptotic process GO:0097285 134 0.143
regulation of signal transduction GO:0009966 318 0.140
Fly
regulation of apoptotic process GO:0042981 335 0.136
intracellular signal transduction GO:0035556 314 0.132
Fly
regulation of rna biosynthetic process GO:2001141 381 0.123
protein complex subunit organization GO:0071822 302 0.114
protein complex assembly GO:0006461 263 0.109
regulation of protein metabolic process GO:0051246 289 0.104
nucleic acid templated transcription GO:0097659 379 0.100
regulation of cellular protein metabolic process GO:0032268 267 0.097
positive regulation of gene expression GO:0010628 244 0.095
positive regulation of transcription dna templated GO:0045893 197 0.088
cellular response to oxygen containing compound GO:1901701 386 0.084
neuron apoptotic process GO:0051402 88 0.083
negative regulation of metabolic process GO:0009892 331 0.080
apoptotic process GO:0006915 381 0.079
positive regulation of nucleic acid templated transcription GO:1903508 197 0.078
rna metabolic process GO:0016070 406 0.077
positive regulation of rna biosynthetic process GO:1902680 197 0.076
positive regulation of rna metabolic process GO:0051254 203 0.076
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.076
regulation of programmed cell death GO:0043067 341 0.076
regulation of rna metabolic process GO:0051252 391 0.075
negative regulation of macromolecule metabolic process GO:0010605 260 0.075
negative regulation of cellular metabolic process GO:0031324 281 0.075
macromolecular complex assembly GO:0065003 273 0.073
programmed cell death GO:0012501 392 0.073
response to extracellular stimulus GO:0009991 380 0.070
regulation of nucleic acid templated transcription GO:1903506 380 0.070
transcription dna templated GO:0006351 377 0.069
macromolecular complex subunit organization GO:0043933 339 0.069
protein complex biogenesis GO:0070271 263 0.067
protein oligomerization GO:0051259 191 0.067
single organism reproductive process GO:0044702 297 0.066
cellular protein localization GO:0034613 122 0.065
cellular component movement GO:0006928 248 0.065
regulation of phosphate metabolic process GO:0019220 349 0.064
regulation of transcription dna templated GO:0006355 374 0.063
negative regulation of apoptotic process GO:0043066 181 0.062
cellular component biogenesis GO:0044085 368 0.062
reproductive process GO:0022414 372 0.062
negative regulation of cell death GO:0060548 229 0.059
regulation of cell proliferation GO:0042127 359 0.059
nucleotide metabolic process GO:0009117 279 0.058
neuron death GO:0070997 127 0.056
response to cytokine GO:0034097 215 0.054
multi organism reproductive process GO:0044703 262 0.051
rna biosynthetic process GO:0032774 380 0.051
negative regulation of neuron death GO:1901215 69 0.050
regulation of cellular localization GO:0060341 263 0.050
negative regulation of signaling GO:0023057 157 0.049
response to nutrient levels GO:0031667 370 0.049
cellular response to peptide GO:1901653 133 0.049
multicellular organism reproduction GO:0032504 233 0.049
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.049
regulation of molecular function GO:0065009 398 0.048
cellular response to hormone stimulus GO:0032870 247 0.048
regulation of neuron death GO:1901214 115 0.048
nucleobase containing small molecule metabolic process GO:0055086 316 0.048
protein localization GO:0008104 191 0.048
positive regulation of signal transduction GO:0009967 175 0.048
Fly
protein localization to organelle GO:0033365 57 0.047
regulation of protein modification process GO:0031399 194 0.047
response to peptide hormone GO:0043434 278 0.047
cellular response to endogenous stimulus GO:0071495 377 0.047
regulation of establishment of protein localization GO:0070201 69 0.046
regulation of phosphorus metabolic process GO:0051174 349 0.046
positive regulation of cell proliferation GO:0008284 249 0.046
organophosphate metabolic process GO:0019637 370 0.046
response to peptide GO:1901652 292 0.045
negative regulation of programmed cell death GO:0043069 183 0.044
cellular macromolecule localization GO:0070727 122 0.042
carboxylic acid metabolic process GO:0019752 289 0.042
regulation of cellular component organization GO:0051128 368 0.041
regulation of phosphorylation GO:0042325 248 0.041
proteolysis GO:0006508 175 0.040
regulation of response to stress GO:0080134 126 0.039
negative regulation of response to stimulus GO:0048585 155 0.039
protein phosphorylation GO:0006468 345 0.039
positive regulation of programmed cell death GO:0043068 157 0.039
cellular response to cytokine stimulus GO:0071345 127 0.039
positive regulation of phosphate metabolic process GO:0045937 262 0.038
establishment of protein localization GO:0045184 141 0.038
cellular response to nitrogen compound GO:1901699 210 0.038
cellular component assembly GO:0022607 360 0.038
single organism biosynthetic process GO:0044711 342 0.038
organonitrogen compound catabolic process GO:1901565 179 0.038
positive regulation of protein metabolic process GO:0051247 178 0.037
positive regulation of response to stimulus GO:0048584 285 0.037
Fly
positive regulation of apoptotic process GO:0043065 154 0.036
negative regulation of signal transduction GO:0009968 83 0.036
regulation of catabolic process GO:0009894 113 0.036
macromolecule localization GO:0033036 252 0.035
negative regulation of cellular biosynthetic process GO:0031327 161 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.035
regulation of neuron apoptotic process GO:0043523 83 0.035
reproductive system development GO:0061458 128 0.034
positive regulation of intracellular signal transduction GO:1902533 138 0.034
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.033
ribonucleotide metabolic process GO:0009259 231 0.033
regulation of locomotion GO:0040012 148 0.032
positive regulation of cell death GO:0010942 184 0.032
multi multicellular organism process GO:0044706 138 0.032
cellular response to stress GO:0033554 269 0.032
tissue development GO:0009888 252 0.031
purine nucleotide metabolic process GO:0006163 229 0.031
regulation of intracellular signal transduction GO:1902531 218 0.031
Fly
purine containing compound metabolic process GO:0072521 253 0.031
purine ribonucleotide metabolic process GO:0009150 227 0.031
negative regulation of multicellular organismal process GO:0051241 203 0.031
nucleoside phosphate metabolic process GO:0006753 283 0.031
cellular ketone metabolic process GO:0042180 51 0.031
negative regulation of gene expression GO:0010629 199 0.030
positive regulation of signaling GO:0023056 270 0.030
Fly
neuron differentiation GO:0030182 368 0.030
regulation of cell motility GO:2000145 131 0.030
catabolic process GO:0009056 351 0.030
multicellular organismal reproductive process GO:0048609 233 0.030
homeostatic process GO:0042592 331 0.029
rhythmic process GO:0048511 156 0.029
negative regulation of protein metabolic process GO:0051248 114 0.029
negative regulation of cellular protein metabolic process GO:0032269 106 0.029
negative regulation of neuron apoptotic process GO:0043524 45 0.029
cell projection organization GO:0030030 302 0.029
response to inorganic substance GO:0010035 377 0.029
cation transport GO:0006812 382 0.028
cellular amine metabolic process GO:0044106 38 0.028
enzyme linked receptor protein signaling pathway GO:0007167 116 0.028
positive regulation of cell development GO:0010720 176 0.027
response to decreased oxygen levels GO:0036293 237 0.027
regulation of catalytic activity GO:0050790 304 0.027
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.027
ribose phosphate metabolic process GO:0019693 235 0.026
positive regulation of cellular component organization GO:0051130 200 0.026
cellular response to organonitrogen compound GO:0071417 197 0.026
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.026
organelle organization GO:0006996 266 0.026
regulation of cell differentiation GO:0045595 320 0.026
regulation of cellular amine metabolic process GO:0033238 8 0.026
response to biotic stimulus GO:0009607 226 0.026
negative regulation of molecular function GO:0044092 133 0.026
regulation of protein transport GO:0051223 68 0.025
positive regulation of locomotion GO:0040017 102 0.025
regulation of cellular ketone metabolic process GO:0010565 27 0.025
translation GO:0006412 35 0.025
Fly
carbohydrate derivative metabolic process GO:1901135 346 0.025
positive regulation of molecular function GO:0044093 230 0.025
neurological system process GO:0050877 219 0.025
positive regulation of transport GO:0051050 245 0.025
gamete generation GO:0007276 124 0.025
positive regulation of phosphorus metabolic process GO:0010562 262 0.024
positive regulation of cellular protein metabolic process GO:0032270 167 0.024
immune system process GO:0002376 204 0.024
protein transport GO:0015031 132 0.024
central nervous system development GO:0007417 311 0.024
purine ribonucleoside metabolic process GO:0046128 168 0.024
organophosphate biosynthetic process GO:0090407 143 0.023
circulatory system development GO:0072359 134 0.023
regulation of membrane potential GO:0042391 110 0.023
cell morphogenesis involved in differentiation GO:0000904 119 0.023
cellular response to oxidative stress GO:0034599 76 0.022
head development GO:0060322 247 0.022
positive regulation of phosphorylation GO:0042327 177 0.022
growth GO:0040007 165 0.022
regulation of protein targeting GO:1903533 28 0.022
regulation of homeostatic process GO:0032844 101 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.022
amine metabolic process GO:0009308 38 0.022
apoptotic signaling pathway GO:0097190 27 0.022
positive regulation of cell differentiation GO:0045597 217 0.021
regulation of peptide transport GO:0090087 87 0.021
negative regulation of biosynthetic process GO:0009890 168 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
negative regulation of cell communication GO:0010648 158 0.021
negative regulation of nucleic acid templated transcription GO:1903507 117 0.021
response to molecule of bacterial origin GO:0002237 194 0.021
positive regulation of cell migration GO:0030335 96 0.021
neuron projection development GO:0031175 273 0.021
female pregnancy GO:0007565 122 0.021
cellular component morphogenesis GO:0032989 155 0.020
nucleotide biosynthetic process GO:0009165 98 0.020
positive regulation of multicellular organismal process GO:0051240 387 0.020
cell growth GO:0016049 104 0.020
peptidyl amino acid modification GO:0018193 126 0.020
transcription from rna polymerase ii promoter GO:0006366 252 0.020
regulation of cellular response to stress GO:0080135 49 0.020
cellular response to growth factor stimulus GO:0071363 162 0.020
regulation of cell migration GO:0030334 128 0.020
nucleoside phosphate biosynthetic process GO:1901293 102 0.020
response to oxidative stress GO:0006979 186 0.020
sexual reproduction GO:0019953 148 0.020
protein maturation GO:0051604 68 0.019
protein homooligomerization GO:0051260 91 0.019
gland development GO:0048732 155 0.019
regulation of kinase activity GO:0043549 117 0.019
response to nutrient GO:0007584 248 0.019
regulation of nucleocytoplasmic transport GO:0046822 28 0.019
regulation of cell development GO:0060284 263 0.019
negative regulation of cellular component organization GO:0051129 83 0.019
vesicle mediated transport GO:0016192 181 0.019
positive regulation of cell projection organization GO:0031346 111 0.019
cellular response to organic cyclic compound GO:0071407 202 0.019
regulation of nucleotide metabolic process GO:0006140 117 0.019
positive regulation of developmental process GO:0051094 283 0.019
regulation of neurogenesis GO:0050767 247 0.018
mapk cascade GO:0000165 140 0.018
regulation of ion transport GO:0043269 245 0.018
reproductive structure development GO:0048608 128 0.018
carbohydrate metabolic process GO:0005975 130 0.018
cellular response to lipid GO:0071396 201 0.018
locomotion GO:0040011 237 0.018
axon development GO:0061564 96 0.018
cellular chemical homeostasis GO:0055082 247 0.018
axonogenesis GO:0007409 71 0.018
cell morphogenesis GO:0000902 142 0.018
dna metabolic process GO:0006259 96 0.018
purine containing compound biosynthetic process GO:0072522 85 0.018
regulation of hydrolase activity GO:0051336 143 0.018
response to growth factor GO:0070848 189 0.017
cellular homeostasis GO:0019725 252 0.017
signal transduction by phosphorylation GO:0023014 144 0.017
macroautophagy GO:0016236 4 0.017
regulation of immune system process GO:0002682 123 0.017
anatomical structure morphogenesis GO:0009653 298 0.017
single organism catabolic process GO:0044712 283 0.017
cellular response to external stimulus GO:0071496 118 0.017
regulation of metal ion transport GO:0010959 118 0.017
localization of cell GO:0051674 202 0.017
regulation of hormone levels GO:0010817 187 0.017
gonad development GO:0008406 104 0.017
negative regulation of developmental process GO:0051093 125 0.017
cellular catabolic process GO:0044248 295 0.017
ribonucleoside metabolic process GO:0009119 174 0.017
cell cycle GO:0007049 101 0.017
positive regulation of cell communication GO:0010647 271 0.017
Fly
organic substance catabolic process GO:1901575 316 0.017
negative regulation of rna metabolic process GO:0051253 123 0.017
cell migration GO:0016477 197 0.017
positive regulation of cellular component movement GO:0051272 102 0.016
cellular lipid metabolic process GO:0044255 208 0.016
cellular carbohydrate metabolic process GO:0044262 72 0.016
response to carbohydrate GO:0009743 183 0.016
regulation of protein localization GO:0032880 81 0.016
single organism organelle organization GO:1902589 180 0.016
wnt signaling pathway GO:0016055 17 0.016
negative regulation of transcription dna templated GO:0045892 116 0.016
response to hypoxia GO:0001666 231 0.016
response to reactive oxygen species GO:0000302 120 0.016
developmental process involved in reproduction GO:0003006 159 0.016
cellular response to biotic stimulus GO:0071216 59 0.016
regulation of cellular catabolic process GO:0031329 101 0.016
regulation of system process GO:0044057 208 0.016
positive regulation of cytoplasmic transport GO:1903651 32 0.015
response to temperature stimulus GO:0009266 94 0.015
inflammatory response GO:0006954 150 0.015
muscle cell apoptotic process GO:0010657 30 0.015
response to bacterium GO:0009617 200 0.015
purine nucleoside metabolic process GO:0042278 169 0.015
response to ketone GO:1901654 182 0.015
guanosine containing compound metabolic process GO:1901068 74 0.015
organic acid metabolic process GO:0006082 292 0.015
positive regulation of response to external stimulus GO:0032103 51 0.015
regulation of mapk cascade GO:0043408 116 0.015
purine nucleotide biosynthetic process GO:0006164 83 0.015
neuron projection morphogenesis GO:0048812 122 0.015
negative regulation of phosphorus metabolic process GO:0010563 80 0.015
negative regulation of transport GO:0051051 136 0.015
response to radiation GO:0009314 137 0.015
single organism cellular localization GO:1902580 102 0.015
regulation of neuron differentiation GO:0045664 208 0.015
guanosine containing compound catabolic process GO:1901069 71 0.015
cellular amino acid metabolic process GO:0006520 107 0.015
lipid metabolic process GO:0006629 283 0.015
response to other organism GO:0051707 220 0.015
cytoplasmic transport GO:0016482 115 0.014
intracellular protein transport GO:0006886 79 0.014
nucleoside triphosphate metabolic process GO:0009141 144 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
cellular response to extracellular stimulus GO:0031668 73 0.014
muscle system process GO:0003012 115 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
regeneration GO:0031099 163 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
reproduction GO:0000003 245 0.014
calcium ion homeostasis GO:0055074 162 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
regulation of translation GO:0006417 27 0.014
regulation of multicellular organismal development GO:2000026 376 0.014
purine nucleoside triphosphate metabolic process GO:0009144 141 0.014
regulation of nervous system development GO:0051960 264 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.014
negative regulation of cell cycle phase transition GO:1901988 4 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
protein processing GO:0016485 68 0.014
single organism carbohydrate metabolic process GO:0044723 118 0.014
gastrulation GO:0007369 2 0.014
regulation of protein kinase activity GO:0045859 105 0.014
development of primary sexual characteristics GO:0045137 107 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
regulation of transferase activity GO:0051338 123 0.013
regulation of dna metabolic process GO:0051052 60 0.013
behavior GO:0007610 205 0.013
response to wounding GO:0009611 254 0.013
defense response GO:0006952 194 0.013
dephosphorylation GO:0016311 98 0.013
regulation of protein processing GO:0070613 50 0.013
cellular response to reactive oxygen species GO:0034614 55 0.013
positive regulation of neuron projection development GO:0010976 99 0.013
response to estrogen GO:0043627 232 0.013
organ regeneration GO:0031100 101 0.013
cellular response to peptide hormone stimulus GO:0071375 120 0.013
regulation of cell projection organization GO:0031344 175 0.013
regulation of intracellular transport GO:0032386 65 0.013
learning or memory GO:0007611 90 0.013
calcium ion transport GO:0006816 131 0.013
cell activation GO:0001775 97 0.013
spindle organization GO:0007051 2 0.013
nucleocytoplasmic transport GO:0006913 48 0.013
positive regulation of cell motility GO:2000147 97 0.013
regulation of cellular component movement GO:0051270 150 0.013
glycosyl compound catabolic process GO:1901658 126 0.013
immune response GO:0006955 104 0.013
regulation of cellular component biogenesis GO:0044087 86 0.013
aromatic compound catabolic process GO:0019439 168 0.013
positive regulation of immune system process GO:0002684 90 0.013
positive regulation of intracellular transport GO:0032388 39 0.013
purine ribonucleoside catabolic process GO:0046130 124 0.013
response to external biotic stimulus GO:0043207 221 0.013
ribonucleoside catabolic process GO:0042454 126 0.013
cellular response to nutrient levels GO:0031669 60 0.013
motor neuron axon guidance GO:0008045 1 0.013
positive regulation of protein phosphorylation GO:0001934 135 0.012
brain development GO:0007420 247 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.012
negative regulation of intracellular signal transduction GO:1902532 38 0.012
organonitrogen compound biosynthetic process GO:1901566 167 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
osteoblast differentiation GO:0001649 26 0.012
amide transport GO:0042886 105 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.012
single organism intracellular transport GO:1902582 166 0.012
regulation of neuron projection development GO:0010975 161 0.012
single organism behavior GO:0044708 130 0.012
glycogen metabolic process GO:0005977 23 0.012
positive regulation of dna metabolic process GO:0051054 39 0.012
ion transmembrane transport GO:0034220 365 0.012
neuronal action potential GO:0019228 35 0.012
protein targeting GO:0006605 61 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
cellular response to starvation GO:0009267 27 0.012
positive regulation of nervous system development GO:0051962 178 0.012
chemotaxis GO:0006935 66 0.012
multicellular organismal signaling GO:0035637 44 0.012
embryonic pattern specification GO:0009880 1 0.012
cell motility GO:0048870 202 0.012
posttranscriptional regulation of gene expression GO:0010608 37 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
regulation of proteolysis GO:0030162 66 0.011
negative regulation of innate immune response GO:0045824 4 0.011
cell projection morphogenesis GO:0048858 123 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
regulation of cell activation GO:0050865 50 0.011
regulation of proteasomal protein catabolic process GO:0061136 4 0.011
sex differentiation GO:0007548 113 0.011
negative regulation of nf kappab transcription factor activity GO:0032088 4 0.011
cellular response to alcohol GO:0097306 87 0.011
nucleotide catabolic process GO:0009166 139 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
regulation of response to external stimulus GO:0032101 106 0.011
response to glucocorticoid GO:0051384 223 0.011
peptide transport GO:0015833 97 0.011
renal system development GO:0072001 67 0.011
response to hexose GO:0009746 144 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
negative regulation of phosphate metabolic process GO:0045936 80 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
purine containing compound catabolic process GO:0072523 138 0.011
neuron development GO:0048666 286 0.011
ossification GO:0001503 70 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
action potential GO:0001508 54 0.011
multicellular organism growth GO:0035264 1 0.011
male gamete generation GO:0048232 99 0.011
organophosphate catabolic process GO:0046434 148 0.011
chemical homeostasis GO:0048878 292 0.011
epithelium development GO:0060429 96 0.011
cardiovascular system development GO:0072358 134 0.011
mitotic cell cycle GO:0000278 49 0.011
non canonical wnt signaling pathway GO:0035567 3 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
positive regulation of protein modification process GO:0031401 142 0.011
positive regulation of intracellular protein transport GO:0090316 20 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
nuclear transport GO:0051169 49 0.011
positive regulation of hydrolase activity GO:0051345 86 0.011
intracellular transport GO:0046907 185 0.011
cellular response to molecule of bacterial origin GO:0071219 56 0.011
necroptotic process GO:0070266 2 0.010
response to corticosteroid GO:0031960 235 0.010
response to estradiol GO:0032355 164 0.010
positive regulation of ion transport GO:0043270 94 0.010
leukocyte activation GO:0045321 76 0.010
lipid storage GO:0019915 1 0.010
epithelial cell differentiation GO:0030855 71 0.010
negative regulation of cytokine production GO:0001818 16 0.010
positive regulation of nucleotide metabolic process GO:0045981 91 0.010
blood circulation GO:0008015 183 0.010
nucleosome organization GO:0034728 1 0.010
response to ethanol GO:0045471 162 0.010
oxoacid metabolic process GO:0043436 290 0.010

Eif4b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.014
cancer DOID:162 0 0.014
organ system cancer DOID:0050686 0 0.013