|
|
regulation of transcription dna templated
|
GO:0006355 |
374 |
0.853
|
Human Mouse |
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
381 |
0.737
|
Human Mouse |
|
|
secretion by cell
|
GO:0032940 |
248 |
0.630
|
|
|
|
regulation of rna metabolic process
|
GO:0051252 |
391 |
0.624
|
Human Mouse |
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
247 |
0.598
|
Human Mouse |
|
|
rna biosynthetic process
|
GO:0032774 |
380 |
0.595
|
Human Mouse |
|
|
biological adhesion
|
GO:0022610 |
110 |
0.585
|
Fly |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
116 |
0.575
|
Human Rat |
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
380 |
0.559
|
Human Mouse |
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
267 |
0.540
|
Human Mouse |
|
|
positive regulation of signaling
|
GO:0023056 |
270 |
0.535
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
376 |
0.516
|
Mouse Worm Fly |
|
|
intracellular signal transduction
|
GO:0035556 |
314 |
0.502
|
Human Mouse Rat |
|
|
response to extracellular stimulus
|
GO:0009991 |
380 |
0.491
|
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
252 |
0.461
|
|
|
|
cell motility
|
GO:0048870 |
202 |
0.458
|
|
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
234 |
0.455
|
|
|
|
positive regulation of response to stimulus
|
GO:0048584 |
285 |
0.452
|
Human Mouse Rat Fly |
|
|
regulation of signal transduction
|
GO:0009966 |
318 |
0.439
|
Human Mouse Rat Fly |
|
|
rna metabolic process
|
GO:0016070 |
406 |
0.428
|
Human Mouse |
|
|
response to nutrient
|
GO:0007584 |
248 |
0.409
|
|
|
|
nucleic acid templated transcription
|
GO:0097659 |
379 |
0.403
|
Human Mouse |
|
|
cellular component movement
|
GO:0006928 |
248 |
0.395
|
|
|
|
positive regulation of cell communication
|
GO:0010647 |
271 |
0.391
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
320 |
0.380
|
Fly |
|
|
response to nutrient levels
|
GO:0031667 |
370 |
0.372
|
|
|
|
head development
|
GO:0060322 |
247 |
0.370
|
|
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
197 |
0.363
|
Human Mouse |
|
|
regulation of cellular localization
|
GO:0060341 |
263 |
0.349
|
Human Mouse |
|
|
cation transport
|
GO:0006812 |
382 |
0.327
|
|
|
|
localization of cell
|
GO:0051674 |
202 |
0.322
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
334 |
0.320
|
Human Mouse |
|
|
gland development
|
GO:0048732 |
155 |
0.315
|
|
|
|
regulation of cell development
|
GO:0060284 |
263 |
0.306
|
Fly |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
377 |
0.305
|
Rat |
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
140 |
0.302
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
319 |
0.302
|
Human Mouse |
|
|
cell cell signaling
|
GO:0007267 |
335 |
0.297
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
159 |
0.294
|
Worm Fly |
|
|
tissue development
|
GO:0009888 |
252 |
0.293
|
Mouse Rat Fly |
|
|
tube development
|
GO:0035295 |
89 |
0.293
|
Fly |
|
|
reproductive system development
|
GO:0061458 |
128 |
0.292
|
Worm Fly |
|
|
regulation of molecular function
|
GO:0065009 |
398 |
0.290
|
Human |
|
|
reproductive process
|
GO:0022414 |
372 |
0.287
|
Worm Fly |
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
197 |
0.287
|
Human Mouse |
|
|
regulation of cellular component organization
|
GO:0051128 |
368 |
0.284
|
|
|
|
regulation of phosphorylation
|
GO:0042325 |
248 |
0.281
|
Human Mouse Rat |
|
|
negative regulation of cell death
|
GO:0060548 |
229 |
0.263
|
|
|
|
camp metabolic process
|
GO:0046058 |
63 |
0.258
|
|
|
|
metal ion transport
|
GO:0030001 |
289 |
0.252
|
|
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
387 |
0.246
|
Mouse Worm |
|
|
transcription dna templated
|
GO:0006351 |
377 |
0.241
|
Human Mouse |
|
|
cell part morphogenesis
|
GO:0032990 |
123 |
0.241
|
Rat |
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
242 |
0.240
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
283 |
0.240
|
Mouse Worm |
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
319 |
0.238
|
Human Mouse |
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
262 |
0.235
|
Human Mouse Rat |
|
|
negative regulation of cell communication
|
GO:0010648 |
158 |
0.234
|
Fly |
|
|
circadian rhythm
|
GO:0007623 |
88 |
0.231
|
Rat |
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
203 |
0.230
|
Human Mouse |
|
|
development of primary sexual characteristics
|
GO:0045137 |
107 |
0.226
|
Fly |
|
|
cation transmembrane transport
|
GO:0098655 |
263 |
0.224
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
359 |
0.220
|
|
|
|
behavior
|
GO:0007610 |
205 |
0.220
|
Fly |
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
218 |
0.220
|
Human Mouse Rat |
|
|
sodium ion transport
|
GO:0006814 |
82 |
0.213
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
162 |
0.211
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
208 |
0.210
|
|
|
|
gonad development
|
GO:0008406 |
104 |
0.210
|
Fly |
|
|
positive regulation of transcription from rna polymerase ii promoter
|
GO:0045944 |
148 |
0.208
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
2 |
0.206
|
|
|
|
forebrain development
|
GO:0030900 |
98 |
0.205
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
175 |
0.205
|
Human Mouse Rat |
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
161 |
0.203
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
341 |
0.200
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
142 |
0.199
|
Human Mouse |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
217 |
0.197
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
157 |
0.196
|
Fly |
|
|
positive regulation of neurogenesis
|
GO:0050769 |
165 |
0.194
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
119 |
0.192
|
Rat |
|
|
regulation of nervous system development
|
GO:0051960 |
264 |
0.191
|
|
|
|
oxoacid metabolic process
|
GO:0043436 |
290 |
0.188
|
|
|
|
reproductive structure development
|
GO:0048608 |
128 |
0.186
|
Worm Fly |
|
|
cellular ketone metabolic process
|
GO:0042180 |
51 |
0.185
|
|
|
|
programmed cell death
|
GO:0012501 |
392 |
0.184
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
249 |
0.183
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
229 |
0.183
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
27 |
0.182
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
386 |
0.181
|
Rat |
|
|
nucleotide metabolic process
|
GO:0009117 |
279 |
0.181
|
|
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
161 |
0.173
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
162 |
0.172
|
|
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
346 |
0.172
|
|
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
123 |
0.171
|
|
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
153 |
0.170
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
349 |
0.170
|
Human Mouse Rat |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
177 |
0.170
|
Human Mouse Rat |
|
|
regulation of protein modification process
|
GO:0031399 |
194 |
0.169
|
Human Mouse |
|
|
negative regulation of cellular macromolecule biosynthetic process
|
GO:2000113 |
141 |
0.167
|
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
168 |
0.165
|
|
|
|
organelle organization
|
GO:0006996 |
266 |
0.163
|
Human |
|
|
positive regulation of cell development
|
GO:0010720 |
176 |
0.162
|
|
|
|
single organism catabolic process
|
GO:0044712 |
283 |
0.162
|
|
|
|
central nervous system development
|
GO:0007417 |
311 |
0.162
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
175 |
0.160
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
123 |
0.159
|
Rat |
|
|
negative regulation of response to stimulus
|
GO:0048585 |
155 |
0.158
|
Fly |
|
|
response to wounding
|
GO:0009611 |
254 |
0.158
|
Mouse Rat Fly |
|
|
ribonucleotide metabolic process
|
GO:0009259 |
231 |
0.158
|
|
|
|
heart morphogenesis
|
GO:0003007 |
3 |
0.156
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
247 |
0.155
|
|
|
|
positive regulation of renin secretion into blood stream
|
GO:1900135 |
1 |
0.154
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
155 |
0.153
|
Rat Fly |
|
|
anatomical structure morphogenesis
|
GO:0009653 |
298 |
0.149
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
208 |
0.149
|
|
|
|
regeneration
|
GO:0031099 |
163 |
0.148
|
Mouse |
|
|
positive regulation of muscle organ development
|
GO:0048636 |
13 |
0.147
|
Mouse |
|
|
epithelium development
|
GO:0060429 |
96 |
0.146
|
Mouse Fly |
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
281 |
0.146
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
168 |
0.146
|
|
|
|
cell adhesion
|
GO:0007155 |
110 |
0.145
|
Fly |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
85 |
0.144
|
Human Rat |
|
|
negative regulation of metabolic process
|
GO:0009892 |
331 |
0.143
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
138 |
0.143
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
122 |
0.143
|
Rat |
|
|
regulation of sodium ion transmembrane transporter activity
|
GO:2000649 |
4 |
0.143
|
|
|
|
brain development
|
GO:0007420 |
247 |
0.143
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
97 |
0.141
|
|
|
|
protein phosphorylation
|
GO:0006468 |
345 |
0.138
|
Human Mouse Rat |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
141 |
0.137
|
Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
8 |
0.137
|
|
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
197 |
0.137
|
Human Mouse |
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
295 |
0.134
|
Human Mouse |
|
|
neuron development
|
GO:0048666 |
286 |
0.134
|
Rat |
|
|
cell morphogenesis
|
GO:0000902 |
142 |
0.133
|
Rat |
|
|
single organism cell adhesion
|
GO:0098602 |
46 |
0.132
|
Fly |
|
|
positive regulation of nervous system development
|
GO:0051962 |
178 |
0.131
|
|
|
|
defense response
|
GO:0006952 |
194 |
0.131
|
|
|
|
response to growth factor
|
GO:0070848 |
189 |
0.131
|
|
|
|
taxis
|
GO:0042330 |
67 |
0.131
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
106 |
0.130
|
Rat |
|
|
regulation of protein phosphorylation
|
GO:0001932 |
183 |
0.128
|
Human Mouse |
|
|
locomotion
|
GO:0040011 |
237 |
0.126
|
|
|
|
regulation of secretion
|
GO:0051046 |
224 |
0.125
|
|
|
|
negative regulation of nucleic acid templated transcription
|
GO:1903507 |
117 |
0.125
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
118 |
0.124
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
110 |
0.124
|
|
|
|
regulation of system process
|
GO:0044057 |
208 |
0.123
|
|
|
|
lipid metabolic process
|
GO:0006629 |
283 |
0.122
|
Human |
|
|
cellular homeostasis
|
GO:0019725 |
252 |
0.119
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
210 |
0.119
|
Rat |
|
|
regulation of hydrolase activity
|
GO:0051336 |
143 |
0.118
|
|
|
|
positive regulation of gene expression
|
GO:0010628 |
244 |
0.117
|
Human Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
107 |
0.117
|
|
|
|
female gonad development
|
GO:0008585 |
53 |
0.116
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
80 |
0.116
|
|
|
|
neuron projection development
|
GO:0031175 |
273 |
0.113
|
Rat |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
181 |
0.113
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
161 |
0.112
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
144 |
0.111
|
Human Rat |
|
|
forebrain generation of neurons
|
GO:0021872 |
8 |
0.111
|
Mouse |
|
|
sex differentiation
|
GO:0007548 |
113 |
0.110
|
Worm Fly |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
119 |
0.110
|
Human |
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
178 |
0.109
|
Human Mouse |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
200 |
0.109
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
349 |
0.109
|
Human Mouse Rat |
|
|
male sex differentiation
|
GO:0046661 |
64 |
0.108
|
Worm |
|
|
positive regulation of intracellular signal transduction
|
GO:1902533 |
138 |
0.108
|
Human Mouse Rat |
|
|
monovalent inorganic cation transport
|
GO:0015672 |
172 |
0.107
|
|
|
|
heart process
|
GO:0003015 |
57 |
0.107
|
Fly |
|
|
response to estrogen
|
GO:0043627 |
232 |
0.106
|
|
|
|
regulation of ion transport
|
GO:0043269 |
245 |
0.106
|
|
|
|
mapk cascade
|
GO:0000165 |
140 |
0.105
|
Human Rat |
|
|
response to ethanol
|
GO:0045471 |
162 |
0.105
|
Fly |
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
202 |
0.104
|
|
|
|
muscle structure development
|
GO:0061061 |
87 |
0.104
|
Mouse Rat |
|
|
cellular amine metabolic process
|
GO:0044106 |
38 |
0.102
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
160 |
0.102
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
1 |
0.101
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
68 |
0.101
|
Human |
|
|
developmental growth
|
GO:0048589 |
100 |
0.101
|
Mouse |
|
|
regulation of protein metabolic process
|
GO:0051246 |
289 |
0.100
|
Human Mouse |
|
|
negative regulation of rna biosynthetic process
|
GO:1902679 |
118 |
0.100
|
|
|
|
positive regulation of molecular function
|
GO:0044093 |
230 |
0.100
|
Human |
|
|
amine metabolic process
|
GO:0009308 |
38 |
0.100
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
183 |
0.097
|
|
|
|
secretion
|
GO:0046903 |
307 |
0.097
|
Human Mouse |
|
|
cellular ion homeostasis
|
GO:0006873 |
184 |
0.096
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
47 |
0.096
|
|
|
|
skeletal muscle tissue development
|
GO:0007519 |
31 |
0.096
|
Rat |
|
|
circulatory system process
|
GO:0003013 |
183 |
0.096
|
Fly |
|
|
regulation of organ growth
|
GO:0046620 |
13 |
0.095
|
Mouse |
|
|
negative regulation of macromolecule biosynthetic process
|
GO:0010558 |
148 |
0.095
|
|
|
|
embryo development
|
GO:0009790 |
49 |
0.095
|
Mouse Fly |
|
|
carboxylic acid metabolic process
|
GO:0019752 |
289 |
0.094
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
48 |
0.093
|
|
|
|
neuron differentiation
|
GO:0030182 |
368 |
0.093
|
Mouse Rat Fly |
|
|
positive regulation of phosphate metabolic process
|
GO:0045937 |
262 |
0.092
|
Human Mouse Rat |
|
|
regulation of ossification
|
GO:0030278 |
32 |
0.091
|
|
|
|
ion homeostasis
|
GO:0050801 |
212 |
0.091
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
21 |
0.091
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
25 |
0.091
|
Mouse |
|
|
negative regulation of gene expression
|
GO:0010629 |
199 |
0.090
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
50 |
0.090
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
54 |
0.089
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
365 |
0.089
|
|
|
|
negative regulation of transcription dna templated
|
GO:0045892 |
116 |
0.089
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
127 |
0.088
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
186 |
0.088
|
|
|
|
protein transport
|
GO:0015031 |
132 |
0.088
|
Human Mouse |
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
80 |
0.086
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
247 |
0.086
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
197 |
0.086
|
Rat |
|
|
cell type specific apoptotic process
|
GO:0097285 |
134 |
0.086
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
125 |
0.085
|
Fly |
|
|
regulation of transferase activity
|
GO:0051338 |
123 |
0.085
|
Human |
|
|
positive regulation of secretion
|
GO:0051047 |
140 |
0.084
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
26 |
0.084
|
Mouse Fly |
|
|
regulation of catalytic activity
|
GO:0050790 |
304 |
0.084
|
Human |
|
|
cation homeostasis
|
GO:0055080 |
195 |
0.083
|
|
|
|
muscle system process
|
GO:0003012 |
115 |
0.082
|
|
|
|
organic acid metabolic process
|
GO:0006082 |
292 |
0.081
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
19 |
0.081
|
|
|
|
rhythmic process
|
GO:0048511 |
156 |
0.081
|
Rat |
|
|
organ formation
|
GO:0048645 |
3 |
0.081
|
|
|
|
apoptotic process
|
GO:0006915 |
381 |
0.080
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
335 |
0.079
|
|
|
|
regulation of growth
|
GO:0040008 |
105 |
0.078
|
Mouse |
|
|
muscle contraction
|
GO:0006936 |
88 |
0.078
|
|
|
|
response to hypoxia
|
GO:0001666 |
231 |
0.077
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
61 |
0.077
|
Human |
|
|
mesonephric tubule development
|
GO:0072164 |
14 |
0.077
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
180 |
0.077
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
87 |
0.076
|
|
|
|
telencephalon development
|
GO:0021537 |
62 |
0.076
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
247 |
0.076
|
Rat |
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
81 |
0.075
|
|
|
|
circulatory system development
|
GO:0072359 |
134 |
0.075
|
Mouse |
|
|
single organism reproductive process
|
GO:0044702 |
297 |
0.074
|
Worm Fly |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
172 |
0.074
|
|
|
|
cellular component biogenesis
|
GO:0044085 |
368 |
0.074
|
Fly |
|
|
cell growth
|
GO:0016049 |
104 |
0.074
|
|
|
|
hormone transport
|
GO:0009914 |
121 |
0.073
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
316 |
0.073
|
|
|
|
growth
|
GO:0040007 |
165 |
0.072
|
Mouse |
|
|
purine nucleotide metabolic process
|
GO:0006163 |
229 |
0.072
|
|
|
|
response to cytokine
|
GO:0034097 |
215 |
0.072
|
|
|
|
hormone secretion
|
GO:0046879 |
115 |
0.072
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.071
|
|
|
|
response to starvation
|
GO:0042594 |
59 |
0.071
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
106 |
0.070
|
|
|
|
inflammatory response
|
GO:0006954 |
150 |
0.070
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
115 |
0.069
|
|
|
|
single organism biosynthetic process
|
GO:0044711 |
342 |
0.068
|
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
260 |
0.068
|
|
|
|
axon development
|
GO:0061564 |
96 |
0.067
|
Rat |
|
|
negative regulation of transport
|
GO:0051051 |
136 |
0.066
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
45 |
0.066
|
Mouse |
|
|
regulation of camp metabolic process
|
GO:0030814 |
43 |
0.066
|
|
|
|
adult behavior
|
GO:0030534 |
16 |
0.066
|
Fly |
|
|
cell projection organization
|
GO:0030030 |
302 |
0.066
|
Rat Fly |
|
|
heart contraction
|
GO:0060047 |
57 |
0.066
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
62 |
0.065
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
36 |
0.065
|
Rat |
|
|
oxidation reduction process
|
GO:0055114 |
304 |
0.065
|
|
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
93 |
0.065
|
|
|
|
n methyl d aspartate receptor clustering
|
GO:0097114 |
2 |
0.064
|
|
|
|
negative regulation of uterine smooth muscle contraction
|
GO:0070473 |
2 |
0.063
|
|
|
|
dorsal ventral axon guidance
|
GO:0033563 |
1 |
0.063
|
|
|
|
homeostatic process
|
GO:0042592 |
331 |
0.063
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
83 |
0.062
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
56 |
0.061
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
3 |
0.061
|
|
|
|
response to estradiol
|
GO:0032355 |
164 |
0.061
|
|
|
|
salivary gland development
|
GO:0007431 |
3 |
0.061
|
Fly |
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
87 |
0.060
|
|
|
|
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure
|
GO:0001999 |
1 |
0.060
|
|
|
|
chemotaxis
|
GO:0006935 |
66 |
0.059
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
229 |
0.059
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
51 |
0.059
|
|
|
|
chemical homeostasis
|
GO:0048878 |
292 |
0.059
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
283 |
0.059
|
|
|
|
response to inorganic substance
|
GO:0010035 |
377 |
0.058
|
|
|
|
single organism behavior
|
GO:0044708 |
130 |
0.058
|
Fly |
|
|
organophosphate biosynthetic process
|
GO:0090407 |
143 |
0.058
|
|
|
|
regulation of neuron death
|
GO:1901214 |
115 |
0.058
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
80 |
0.057
|
|
|
|
eye development
|
GO:0001654 |
50 |
0.057
|
Fly |
|
|
positive regulation of blood pressure by epinephrine norepinephrine
|
GO:0003321 |
2 |
0.057
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
122 |
0.057
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
4 |
0.057
|
|
|
|
regulation of striated muscle contraction
|
GO:0006942 |
21 |
0.057
|
|
|
|
sensory organ development
|
GO:0007423 |
74 |
0.057
|
Rat Fly |
|
|
neural crest cell migration
|
GO:0001755 |
1 |
0.057
|
Mouse |
|
|
blood circulation
|
GO:0008015 |
183 |
0.056
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.055
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
203 |
0.055
|
Fly |
|
|
calcium ion homeostasis
|
GO:0055074 |
162 |
0.055
|
|
|
|
organophosphate metabolic process
|
GO:0019637 |
370 |
0.054
|
Human |
|
|
axonogenesis
|
GO:0007409 |
71 |
0.054
|
Rat |
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
167 |
0.054
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
67 |
0.054
|
Human |
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
227 |
0.054
|
|
|
|
positive regulation of cardiac muscle cell proliferation
|
GO:0060045 |
4 |
0.054
|
Mouse |
|
|
glycosyl compound metabolic process
|
GO:1901657 |
182 |
0.053
|
|
|
|
reproduction
|
GO:0000003 |
245 |
0.053
|
Worm Fly |
|
|
cardiac chamber development
|
GO:0003205 |
1 |
0.053
|
|
|
|
signal release
|
GO:0023061 |
145 |
0.053
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
5 |
0.053
|
|
|
|
dendrite morphogenesis
|
GO:0048813 |
43 |
0.052
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
73 |
0.052
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
101 |
0.052
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
106 |
0.052
|
|
|
|
wound healing
|
GO:0042060 |
122 |
0.051
|
Mouse Fly |
|
|
sequestering of calcium ion
|
GO:0051208 |
8 |
0.051
|
|
|
|
regulation of synaptic transmission
|
GO:0050804 |
141 |
0.051
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
133 |
0.051
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
44 |
0.051
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
46 |
0.050
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
140 |
0.050
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
4 |
0.050
|
|
|
|
cellular component assembly
|
GO:0022607 |
360 |
0.050
|
Fly |
|
|
regulation of response to stress
|
GO:0080134 |
126 |
0.049
|
Fly |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
92 |
0.049
|
Human Rat |
|
|
catabolic process
|
GO:0009056 |
351 |
0.049
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
86 |
0.049
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
62 |
0.049
|
|
|
|
response to radiation
|
GO:0009314 |
137 |
0.048
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
79 |
0.048
|
|
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
167 |
0.048
|
Human Mouse |
|
|
negative regulation of secretion
|
GO:0051048 |
82 |
0.048
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
1 |
0.048
|
|
|
|
specification of organ identity
|
GO:0010092 |
2 |
0.048
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
202 |
0.048
|
|
|
|
cardiac ventricle development
|
GO:0003231 |
1 |
0.047
|
|
|
|
cellular response to stress
|
GO:0033554 |
269 |
0.047
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
48 |
0.047
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
147 |
0.047
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
126 |
0.047
|
|
|
|
olfactory bulb interneuron differentiation
|
GO:0021889 |
1 |
0.046
|
Mouse |
|
|
nephric duct development
|
GO:0072176 |
1 |
0.046
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
135 |
0.046
|
Human Mouse |
|
|
respiratory gaseous exchange
|
GO:0007585 |
4 |
0.046
|
|
|
|
cytokine production
|
GO:0001816 |
61 |
0.046
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
41 |
0.045
|
Human |
|
|
regulation of homeostatic process
|
GO:0032844 |
101 |
0.045
|
|
|
|
neurological system process
|
GO:0050877 |
219 |
0.045
|
Fly |
|
|
purine containing compound metabolic process
|
GO:0072521 |
253 |
0.045
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
49 |
0.045
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
63 |
0.044
|
|
|
|
organic substance catabolic process
|
GO:1901575 |
316 |
0.044
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
111 |
0.044
|
|
|
|
negative regulation of signal transduction
|
GO:0009968 |
83 |
0.043
|
Fly |
|
|
muscle tissue development
|
GO:0060537 |
58 |
0.043
|
Mouse Rat |
|
|
dendrite development
|
GO:0016358 |
72 |
0.043
|
|
|
|
response to corticosteroid
|
GO:0031960 |
235 |
0.042
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
233 |
0.042
|
Worm Fly |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
117 |
0.042
|
|
|
|
response to vitamin
|
GO:0033273 |
131 |
0.042
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
58 |
0.042
|
Mouse Rat |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
75 |
0.041
|
|
|
|
regulation of brown fat cell proliferation
|
GO:0070347 |
1 |
0.041
|
|
|
|
cellular response to lipid
|
GO:0071396 |
201 |
0.041
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
82 |
0.041
|
|
|
|
muscle tissue morphogenesis
|
GO:0060415 |
1 |
0.041
|
|
|
|
cerebral cortex tangential migration
|
GO:0021800 |
1 |
0.041
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
93 |
0.040
|
|
|
|
ovulation cycle process
|
GO:0022602 |
50 |
0.040
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
124 |
0.040
|
|
|
|
cell migration
|
GO:0016477 |
197 |
0.040
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
49 |
0.040
|
|
|
|
positive regulation of the force of heart contraction by norepinephrine
|
GO:0003061 |
1 |
0.039
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
99 |
0.039
|
|
|
|
response to light stimulus
|
GO:0009416 |
52 |
0.039
|
|
|
|
response to oxygen levels
|
GO:0070482 |
265 |
0.039
|
|
|
|
regulation of locomotion
|
GO:0040012 |
148 |
0.039
|
|
|
|
female pregnancy
|
GO:0007565 |
122 |
0.039
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
51 |
0.039
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
73 |
0.038
|
|
|
|
regulation of cell growth
|
GO:0001558 |
85 |
0.038
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
98 |
0.038
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
126 |
0.038
|
Human Mouse Rat |
|
|
positive regulation of secretion by cell
|
GO:1903532 |
128 |
0.038
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
22 |
0.038
|
Fly |
|
|
sensory perception of pain
|
GO:0019233 |
73 |
0.038
|
|
|
|
adrenergic receptor signaling pathway
|
GO:0071875 |
9 |
0.037
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
235 |
0.037
|
|
|
|
potassium ion transport
|
GO:0006813 |
97 |
0.037
|
|
|
|
response to glucose
|
GO:0009749 |
136 |
0.037
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
48 |
0.037
|
|
|
|
regulation of glucose transport
|
GO:0010827 |
18 |
0.036
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
184 |
0.036
|
|
|
|
positive regulation of catalytic activity
|
GO:0043085 |
184 |
0.036
|
Human |
|
|
regulation of cell adhesion
|
GO:0030155 |
52 |
0.036
|
|
|
|
atp metabolic process
|
GO:0046034 |
72 |
0.036
|
|
|
|
neurotransmitter gated ion channel clustering
|
GO:0072578 |
3 |
0.036
|
|
|
|
cardiac muscle tissue morphogenesis
|
GO:0055008 |
1 |
0.036
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
38 |
0.036
|
|
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
17 |
0.036
|
|
|
|
response to testosterone
|
GO:0033574 |
55 |
0.036
|
|
|
|
mesonephric epithelium development
|
GO:0072163 |
14 |
0.036
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
105 |
0.035
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
94 |
0.035
|
|
|
|
tangential migration from the subventricular zone to the olfactory bulb
|
GO:0022028 |
1 |
0.035
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
102 |
0.035
|
|
|
|
embryonic pattern specification
|
GO:0009880 |
1 |
0.035
|
Mouse Fly |
|
|
sodium ion transmembrane transport
|
GO:0035725 |
67 |
0.035
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
154 |
0.034
|
|
|
|
positive regulation of long term synaptic potentiation
|
GO:1900273 |
4 |
0.034
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
187 |
0.034
|
|
|
|
cellular catabolic process
|
GO:0044248 |
295 |
0.034
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
79 |
0.034
|
|
|
|
response to nicotine
|
GO:0035094 |
51 |
0.034
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
85 |
0.034
|
|
|
|
response to purine containing compound
|
GO:0014074 |
126 |
0.034
|
|
|
|
macromolecular complex assembly
|
GO:0065003 |
273 |
0.034
|
|
|
|
muscle organ development
|
GO:0007517 |
50 |
0.033
|
Mouse Rat |
|
|
cytoskeleton organization
|
GO:0007010 |
111 |
0.033
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
51 |
0.033
|
|
|
|
positive regulation of the force of heart contraction by epinephrine norepinephrine
|
GO:0001997 |
2 |
0.033
|
|
|
|
immune response
|
GO:0006955 |
104 |
0.033
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
233 |
0.033
|
Worm Fly |
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
102 |
0.033
|
|
|
|
liver development
|
GO:0001889 |
90 |
0.033
|
Rat |
|
|
macromolecular complex subunit organization
|
GO:0043933 |
339 |
0.033
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
122 |
0.033
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
136 |
0.033
|
|
|
|
cellular response to alcohol
|
GO:0097306 |
87 |
0.032
|
|
|
|
response to ketone
|
GO:1901654 |
182 |
0.032
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
136 |
0.032
|
|
|
|
digestive system development
|
GO:0055123 |
41 |
0.032
|
Fly |
|
|
negative regulation of nucleotide metabolic process
|
GO:0045980 |
23 |
0.032
|
|
|
|
organ induction
|
GO:0001759 |
1 |
0.032
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
94 |
0.032
|
|
|
|
peptide secretion
|
GO:0002790 |
86 |
0.032
|
|
|
|
negative regulation of neurogenesis
|
GO:0050768 |
78 |
0.032
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
65 |
0.032
|
|
|
|
regulation of protein localization
|
GO:0032880 |
81 |
0.031
|
Human Mouse |
|
|
heart development
|
GO:0007507 |
72 |
0.031
|
Mouse |
|
|
male gonad development
|
GO:0008584 |
59 |
0.031
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
157 |
0.031
|
|
|
|
neuron death
|
GO:0070997 |
127 |
0.031
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
117 |
0.031
|
Human |
|
|
regulation of muscle contraction
|
GO:0006937 |
53 |
0.031
|
|
|
|
response to hexose
|
GO:0009746 |
144 |
0.031
|
|
|
|
cellular potassium ion transport
|
GO:0071804 |
72 |
0.030
|
|
|
|
response to monosaccharide
|
GO:0034284 |
159 |
0.030
|
|
|
|
neuron neuron synaptic transmission
|
GO:0007270 |
60 |
0.030
|
|
|
|
developmental induction
|
GO:0031128 |
2 |
0.030
|
|
|
|
response to acid chemical
|
GO:0001101 |
222 |
0.030
|
|
|
|
protein complex subunit organization
|
GO:0071822 |
302 |
0.030
|
|
|
|
response to monoamine
|
GO:0071867 |
17 |
0.029
|
|
|
|
forebrain neuron development
|
GO:0021884 |
3 |
0.029
|
|
|
|
detection of stimulus
|
GO:0051606 |
24 |
0.029
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
42 |
0.029
|
Fly |
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
45 |
0.029
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
124 |
0.029
|
|
|
|
regulation of cell migration
|
GO:0030334 |
128 |
0.029
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
42 |
0.029
|
|
|
|
response to alkaloid
|
GO:0043279 |
132 |
0.029
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
85 |
0.029
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
69 |
0.029
|
Human Mouse |
|
|
calcium mediated signaling
|
GO:0019722 |
23 |
0.029
|
|
|
|
positive regulation of the force of heart contraction by epinephrine
|
GO:0003059 |
1 |
0.029
|
|
|
|
regulation of cell motility
|
GO:2000145 |
131 |
0.029
|
|
|
|
ureteric bud development
|
GO:0001657 |
14 |
0.028
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
110 |
0.028
|
|
|
|
regulation of heart growth
|
GO:0060420 |
12 |
0.028
|
Mouse |
|
|
regulation of mapk cascade
|
GO:0043408 |
116 |
0.028
|
Human Rat |
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
55 |
0.028
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
122 |
0.028
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
141 |
0.028
|
|
|
|
female sex differentiation
|
GO:0046660 |
59 |
0.027
|
|
|
|
membrane depolarization
|
GO:0051899 |
32 |
0.027
|
|
|
|
response to carbohydrate
|
GO:0009743 |
183 |
0.027
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
121 |
0.027
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
9 |
0.027
|
|
|
|
embryonic cranial skeleton morphogenesis
|
GO:0048701 |
2 |
0.027
|
|
|
|
ossification
|
GO:0001503 |
70 |
0.027
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
3 |
0.027
|
|
|
|
protein complex biogenesis
|
GO:0070271 |
263 |
0.027
|
|
|
|
phospholipase c activating serotonin receptor signaling pathway
|
GO:0007208 |
2 |
0.027
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
134 |
0.027
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
27 |
0.027
|
|
|
|
ovulation cycle
|
GO:0042698 |
67 |
0.027
|
|
|
|
axon midline choice point recognition
|
GO:0016199 |
2 |
0.027
|
|
|
|
immune system process
|
GO:0002376 |
204 |
0.026
|
Fly |
|
|
response to mechanical stimulus
|
GO:0009612 |
134 |
0.026
|
|
|
|
positive regulation of transport
|
GO:0051050 |
245 |
0.026
|
|
|
|
response to glucocorticoid
|
GO:0051384 |
223 |
0.026
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
61 |
0.026
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
174 |
0.026
|
|
|
|
regulation of skeletal muscle tissue growth
|
GO:0048631 |
3 |
0.026
|
|
|
|
insulin secretion
|
GO:0030073 |
69 |
0.026
|
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
27 |
0.026
|
|
|
|
gliogenesis
|
GO:0042063 |
93 |
0.026
|
Rat |
